Result of FASTA (omim) for
pF1KB8946
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8946, 313 aa
1>>>pF1KB8946 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1782+/-0.000318; mu= 10.7491+/- 0.020
mean_var=206.1712+/-41.422, 0's: 0 Z-trim(122.8): 196 B-trim: 36 in 1/57
Lambda= 0.089322
statistics sampled from 41181 (41423) to 41181 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.486), width: 16
Scan time: 9.180
The best scores are: opt bits E(85289)
NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313) 2110 283.7 3.4e-76
NP_067015 (OMIM: 142986) homeobox protein Hox-D11 ( 338) 547 82.3 1.5e-15
NP_055027 (OMIM: 605559) homeobox protein Hox-C11 ( 304) 518 78.5 1.9e-14
NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 372 59.8 1.1e-08
NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 367 59.1 1.5e-08
NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 349 56.8 7.5e-08
NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 346 56.2 7.9e-08
NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 328 54.1 4.8e-07
NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 324 53.4 5.8e-07
NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 319 52.8 9.3e-07
NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 297 50.0 6.6e-06
XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 48.9 2.2e-05
XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 48.9 2.2e-05
XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 48.9 2.2e-05
XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 48.9 2.2e-05
NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 287 48.9 2.2e-05
NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 287 48.9 2.2e-05
XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 48.9 2.2e-05
NP_004518 (OMIM: 214300,600147) homeobox protein M ( 254) 278 47.5 3.5e-05
XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 280 48.0 4.1e-05
XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 280 48.0 4.1e-05
XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 280 48.0 4.1e-05
XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 280 48.0 4.1e-05
NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 280 48.0 4.1e-05
XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 280 48.0 4.1e-05
XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 280 48.0 4.1e-05
XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 280 48.0 4.1e-05
NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 277 47.5 4.7e-05
NP_067016 (OMIM: 142988) homeobox protein Hox-D12 ( 270) 275 47.1 4.7e-05
XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 276 47.3 4.8e-05
NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 271 46.6 6.7e-05
NP_001035091 (OMIM: 214300,600147) homeobox protei ( 139) 264 45.4 8.2e-05
NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 267 46.1 9.5e-05
NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 264 45.6 0.00011
NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 265 45.9 0.00013
NP_000513 (OMIM: 140000,142959,176305) homeobox pr ( 388) 265 46.0 0.00015
NP_001186675 (OMIM: 142985) homeobox protein Hox-D ( 289) 262 45.5 0.00016
NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 261 45.3 0.00017
NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 257 44.7 0.00021
NP_062458 (OMIM: 142985) homeobox protein Hox-D8 i ( 290) 258 45.0 0.00023
NP_059106 (OMIM: 142976,614931) homeobox protein H ( 330) 258 45.0 0.00025
NP_005915 (OMIM: 600535) homeobox protein MOX-2 [H ( 304) 257 44.9 0.00025
XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 252 44.1 0.00034
NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 253 44.4 0.00038
NP_776272 (OMIM: 142975) homeobox protein Hox-C12 ( 282) 251 44.0 0.00041
XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 250 43.9 0.00046
NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 248 43.6 0.00049
XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 248 43.6 0.00049
XP_011533181 (OMIM: 600297) PREDICTED: homeobox pr ( 196) 246 43.2 0.00051
NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 245 43.2 0.00063
>>NP_005514 (OMIM: 142958,605432) homeobox protein Hox-A (313 aa)
initn: 2110 init1: 2110 opt: 2110 Z-score: 1488.9 bits: 283.7 E(85289): 3.4e-76
Smith-Waterman score: 2110; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)
10 20 30 40 50 60
pF1KB8 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 AAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKIN
250 260 270 280 290 300
310
pF1KB8 RDRLQYYSANPLL
:::::::::::::
NP_005 RDRLQYYSANPLL
310
>>NP_067015 (OMIM: 142986) homeobox protein Hox-D11 [Hom (338 aa)
initn: 871 init1: 507 opt: 547 Z-score: 400.0 bits: 82.3 E(85289): 1.5e-15
Smith-Waterman score: 900; 48.5% identity (63.1% similar) in 355 aa overlap (2-313:3-338)
10 20 30 40 50
pF1KB8 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNL-PQVQPVR
:::: : ...::::.:.:::. ::.: :::: : ::: ::. ::::: :.:::::
NP_067 MNDFDECGQSAASMYLPGCAYYVAPSDFASKPSFLSQ-PSSCQMTFPYSSNLAPHVQPVR
10 20 30 40 50
60 70 80
pF1KB8 EVTFREYAIEPATKWHPRGN-----------------------------------LAHCY
::.::.:..: : :: ::. :
NP_067 EVAFRDYGLERA-KWPYRGGGGGGSAGGGSSGGGPGGGGGGAGGYAPYYAAAAAAAAAAA
60 70 80 90 100 110
90 100 110 120 130
pF1KB8 SAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHPTP-----AVSSNFYSTVGRNGVLPQ
.::: . . : : :: ::: :. : : : ...:::::.:::::.:::
NP_067 AAEEAAMQRELLPP--AGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQ
120 130 140 150 160 170
140 150 160 170 180 190
pF1KB8 AFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGG
.::::.:.: : : . : . :: : .:: : : :.. ::::
NP_067 GFDQFYEAAPGPP-------FAGPQ-----PPPPPAPPQPEGAADKGDPRTGA---GGGG
180 190 200 210 220
200 210 220 230 240 250
pF1KB8 GCRETAAAAEEKERRRRPESSSSPESSSGHT--EDKAGGSSGQRTRKKRCPYTKYQIREL
: : :. . . :... :. :.. : .... . ::.:::::::::::::::
NP_067 GSPCTKATPGSEPKGAAEGSGGDGEGPPGEAGAEKSSSAVAPQRSRKKRCPYTKYQIREL
230 240 250 260 270 280
260 270 280 290 300 310
pF1KB8 EREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
::::::.:::::::::::::::::::::::::::::::::::.:::::::...:::.
NP_067 EREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYFTGNPLF
290 300 310 320 330
>>NP_055027 (OMIM: 605559) homeobox protein Hox-C11 [Hom (304 aa)
initn: 769 init1: 480 opt: 518 Z-score: 380.3 bits: 78.5 E(85289): 1.9e-14
Smith-Waterman score: 959; 52.5% identity (72.6% similar) in 318 aa overlap (2-313:21-304)
10 20 30 40
pF1KB8 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSR
:: ::: :.::.::::::::. :.::.. :::::.:: :
NP_055 MFNSVNLGNFCSPSRKERGADFGERGSCASNLYLPSCTYYM--PEFSTVSSFLPQAPS-R
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 PMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSA-EELVHRDCLQAPSAA
..: ::. :: :::::. :..::. ::: :.. . ::.: .::.::.:: ::..
NP_055 QISYPYSA---QVPPVREVS---YGLEPSGKWHHRNSYSSCYAAADELMHRECLP-PSTV
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 GVPGDVLAKSSANV--YHHPT-P-AVSSNFYSTVGRNGVLPQAFDQFFETAY-GTPENLA
..: :. .. .:::. : :. ..:::.:..:.:::::::.::..:: : . :
NP_055 ---TEILMKNEGSYGGHHHPSAPHATPAGFYSSVNKNSVLPQAFDRFFDNAYCGGGDPPA
120 130 140 150 160
160 170 180 190 200 210
pF1KB8 SSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRR
: :. :: : : .:. :. : .:: : : .:.
NP_055 EPPCSG-KGEAKGEPEAPPASGLASRAEAGAEA-------------------EAEEENTN
170 180 190 200
220 230 240 250 260 270
pF1KB8 PESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLS
: ::.: .: . . :... .. :::::::::.:.:::::::::::.::::::::::::
NP_055 PSSSGSAHSVAKEPA-KGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKEKRLQLS
210 220 230 240 250 260
280 290 300 310
pF1KB8 RMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
:::::::::::::::::::::::..::::::.:.::::
NP_055 RMLNLTDRQVKIWFQNRRMKEKKLSRDRLQYFSGNPLL
270 280 290 300
>>NP_061824 (OMIM: 142957) homeobox protein Hox-A10 [Hom (410 aa)
initn: 370 init1: 307 opt: 372 Z-score: 277.1 bits: 59.8 E(85289): 1.1e-08
Smith-Waterman score: 413; 33.4% identity (57.4% similar) in 326 aa overlap (7-310:111-406)
10 20 30
pF1KB8 MDFDERGPCSSNMYL--P-SCTYYV-SGPDFSSLPS
:: ...: : :: . .:: :.
NP_061 FPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGP--PPPPQ
90 100 110 120 130
40 50 60 70 80 90
pF1KB8 FLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRD
: : . :. ... .: ..: . : . .. :. . .: ::
NP_061 QQPPPPPQPPQPAPQATSCSFAQNIKEES--SYCLYDSADKCPKVS----ATAAEL----
140 150 160 170 180
100 110 120 130 140
pF1KB8 CLQAPSAAGVPGDVLA-KSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFD--QFFETAYG
:: : : : : .:..: :.: ... : ::. . . .. :
NP_061 ---APFPRGPPPDGCALGTSSGV---PVP----GYFR-------LSQAYGTAKGYGSGGG
190 200 210 220 230
150 160 170 180 190 200
pF1KB8 TPENLASSDYPGDKSAEKG---PPAATATSAAAA----AAATGAPATSSSDSGGGGGCRE
..:... .:.. . .: ::: .. :: :: : . : : . ::::. :
NP_061 GAQQLGAGPFPAQPPG-RGFDLPPALASGSADAARKERALDSPPPPTLACGSGGGSQGDE
240 250 260 270 280 290
210 220 230 240 250
pF1KB8 TA----AAAEEKERRRRPESSSSPESSS-GHT--EDKAGGSSGQRTRKKRCPYTKYQIRE
: .:::: :..:::..: :.. :. :. ... :::::::::.: :
NP_061 EAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLE
300 310 320 330 340 350
260 270 280 290 300 310
pF1KB8 LEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRD-RLQYYSANPLL
::.::.:..:...:.::..:: ..:::::::::::::::: ::.::. :.. .::
NP_061 LEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS
360 370 380 390 400 410
>>NP_059105 (OMIM: 605560) homeobox protein Hox-C10 [Hom (342 aa)
initn: 403 init1: 311 opt: 367 Z-score: 274.6 bits: 59.1 E(85289): 1.5e-08
Smith-Waterman score: 387; 32.3% identity (57.4% similar) in 303 aa overlap (23-310:60-338)
10 20 30 40 50
pF1KB8 MDFDERGPCSSNMYLPSCTYYVSGPDFS--SLPSFLPQTPSSRPMTYSYSSN
:.:... . ::.: : : .: .
NP_059 GMYMQSGSDFNCGVMRGCGLAPSLSKRDEGSSPSLALNTYPSYLSQLDSWGDPKAAYRLE
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB8 LPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKS
: .:. .. :..: . :. ::::. .. ..: :: . . : .:
NP_059 QPVGRPLSSCSY-----PPSVK---EENVCCMYSAEKRAK----SGPEAA-LYSHPLPES
90 100 110 120 130
120 130 140 150 160
pF1KB8 SANVYHHPTPAV--SSNFYSTVGRNGVLPQAFD---QFFETAYGTP--ENLASSDYPGDK
. .. :.:. .: ::.. .. : : : . : .: :.: : . :
NP_059 CLGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKV
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB8 SAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPE
: . : . . : . : .: .: :. :. :::: . .:: .
NP_059 SFPETPKSDSQTPSPNEIK------TEQSLAGPKGSPSES-----EKERAKAADSSPDTS
200 210 220 230 240
230 240 250 260 270
pF1KB8 SSSGHTEDKAGGSSG-----QRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRML
.. .. : :: ...: . :::::::::.: :::.::.:..:...:.::..:. .
NP_059 DNEAKEEIKAENTTGNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTI
250 260 270 280 290 300
280 290 300 310
pF1KB8 NLTDRQVKIWFQNRRMKEKKINRD-RLQYYSANPLL
::::::::::::::::: ::.::. :.. ..:
NP_059 NLTDRQVKIWFQNRRMKLKKMNRENRIRELTSNFNFT
310 320 330 340
>>NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [Homo (352 aa)
initn: 441 init1: 305 opt: 349 Z-score: 261.9 bits: 56.8 E(85289): 7.5e-08
Smith-Waterman score: 360; 28.8% identity (57.1% similar) in 312 aa overlap (7-303:55-347)
10 20 30
pF1KB8 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLP-
:: .. . ::.. . ::. : .:
NP_055 LIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPS
30 40 50 60 70 80
40 50 60 70 80
pF1KB8 QTPSSRPMTYSYSSNLPQ-------VQPVREVTFREYAIEPATKWHPRGNLAHCYSAEEL
: :.. :. : .: .: : : : . .:: . : : . ..
NP_055 QPPAAAAMSGLYHPYVPPPPLAASASEPGRYV--RSW-MEPLPGF-PGGAGGGGGGGGGG
90 100 110 120 130 140
90 100 110 120 130 140
pF1KB8 VHRDCLQAPS--AAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFET
: .:: : : . .. : :.::.... :. . . . .
NP_055 PGRGPSPGPSGPANGRHYGIKPETRAA----PAPATAASTTSSSSTS----------LSS
150 160 170 180
150 160 170 180 190 200
pF1KB8 AYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAA
. : .. . :... : . . .::::...:: :... . . : :: : .:
NP_055 SSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTG-PGAGIGAATGTGGSSEPSAC
190 200 210 220 230 240
210 220 230 240 250 260
pF1KB8 AEEK----ERRRRPESSSSPESSSGHTEDKAGGSSGQR-TRKKRCPYTKYQIRELEREFF
... ... .. :.:.... .. :.. : :::::::::::: :::.::.
NP_055 SDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFL
250 260 270 280 290 300
270 280 290 300 310
pF1KB8 FSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
:..:.....: ...:.::::.::::::::::::: ::.....
NP_055 FNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD
310 320 330 340 350
>>NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [Homo (250 aa)
initn: 370 init1: 300 opt: 346 Z-score: 261.5 bits: 56.2 E(85289): 7.9e-08
Smith-Waterman score: 357; 33.1% identity (61.3% similar) in 248 aa overlap (69-303:24-247)
40 50 60 70 80 90
pF1KB8 SSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPS
: .:. : :. : :... : . :. ::
NP_076 MSISGTLSSYYVDSIISHESEDAPPAKF-PSGQYA---SSRQPGHAEHLEFPS
10 20 30 40
100 110 120 130 140 150
pF1KB8 AAGVP-GDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAY-GTPENLAS
. : . :.. : : . : . .. : .. . .:: : : .....: .:.. :.
NP_076 CSFQPKAPVFGASWAPLSPHASGSLPSVYHPYIQPQGV-PPAESRYLRTWLEPAPRGEAA
50 60 70 80 90 100
160 170 180 190 200
pF1KB8 SDYPGD-KSAEKGPPAATATSAAAAAAATGAPATSSSDSGG----------GGGCRETAA
::. ..: :. : .: . :.: : :.: : : .
NP_076 ---PGQGQAAVKAEP---LLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICE
110 120 130 140 150 160
210 220 230 240 250 260
pF1KB8 AAEEKERRRRPESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVY
..:.:: ::.... : .. :... .::::::::::: :::.::.:..:
NP_076 GSEDKE---RPDQTN-PSANWLHARS---------SRKKRCPYTKYQTLELEKEFLFNMY
170 180 190 200
270 280 290 300 310
pF1KB8 INKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
.....: ...:.:::..::::::::::::: ::.:...
NP_076 LTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE
210 220 230 240 250
>>NP_002139 (OMIM: 142984,192950) homeobox protein Hox-D (340 aa)
initn: 374 init1: 303 opt: 328 Z-score: 247.4 bits: 54.1 E(85289): 4.8e-07
Smith-Waterman score: 328; 28.0% identity (54.8% similar) in 314 aa overlap (10-310:31-336)
10 20 30
pF1KB8 MDFDERGPCSSNMYLP--SCTYYVSGPDFSSL-PSFLPQ
:..::.: : . . : . .: ::. .
NP_002 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 TPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEE--LVHRDCL
. . : .. .:::. . . .:.:. : ... . : .. :
NP_002 EVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 QAPSAAGVPG-DVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPEN
. .: ::. . :. : : ..: : . : . : ... : . . .
NP_002 NKLISAEVPSYQRLVPESCPV-ENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQ
130 140 150 160 170
160 170 180 190 200
pF1KB8 LASSDYPGDK-SAEKGPPAATATSAAAAAAATGAPATSSSDSGGG----GGC-RETAAAA
: . :: . . ... : . . : .. :: .: :.....
NP_002 LNPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSS
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 EEKERRRRPESSSSPESSSGHTEDKAGGSSGQRTRKKRCPYTKYQIRELEREFFFSVYIN
: .... : .: .:. :.: :::::::::.: :::.::.:..:..
NP_002 PEVQEKESKEEIKSDTPTSNWLTAKSG-------RKKRCPYTKHQTLELEKEFLFNMYLT
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 KEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRD-RLQYYSANPLL
.:.::..:. .::::::::::::::::: ::..:. :.. .::
NP_002 RERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
300 310 320 330 340
>>NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [Homo (260 aa)
initn: 355 init1: 310 opt: 324 Z-score: 246.0 bits: 53.4 E(85289): 5.8e-07
Smith-Waterman score: 350; 34.8% identity (53.4% similar) in 253 aa overlap (69-303:29-254)
40 50 60 70 80 90
pF1KB8 SSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPS
::: :: . :: :: . ::
NP_008 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAA-----RPSGLVP-DCSDFPS
10 20 30 40 50
100 110 120 130 140 150
pF1KB8 AAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAF---DQFFETAYGTPENLA
. .: .. ..: :.:. :: : : :: : . .. : . :
NP_008 CSFAPKPAVFSTSWA----PVPSQSSVVYHPYG-----PQPHLGADTRYMRTWLEPLSGA
60 70 80 90 100
160 170 180 190 200 210
pF1KB8 SSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCR--ETAAAAEEKERR
: .:. ::. : : : : : : : : . .. . :
NP_008 VS-FPS-------FPAGGRHYALKPDAYPGRRA----DCGPGEGRSYPDYMYGSPGELRD
110 120 130 140 150
220 230 240 250 260
pF1KB8 RRPESSSSPESS----SGHTEDKAGGSSG---------QRTRKKRCPYTKYQIRELEREF
: :.. :::.. : : :.:: . . . :::::::::::: :::.::
NP_008 RAPQTLPSPEADALAGSKHKEEKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEF
160 170 180 190 200 210
270 280 290 300 310
pF1KB8 FFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL
.:..:.....: ...:.::::.::::::::::::: ::.:...
NP_008 LFNMYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS
220 230 240 250 260
>>NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [Homo (272 aa)
initn: 385 init1: 319 opt: 319 Z-score: 242.3 bits: 52.8 E(85289): 9.3e-07
Smith-Waterman score: 376; 29.9% identity (55.8% similar) in 294 aa overlap (12-303:9-268)
10 20 30 40 50 60
pF1KB8 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLPQTPSSRPMTYSYSSNLPQVQPVREV
:.:. : ... : :. . : : .. : . .. :. .:
NP_689 MATTGALGNYYVDSFLLGADAADELSVGRYAPGTLGQPPRQAATLAEHPDFSPC---
10 20 30 40 50
70 80 90 100 110
pF1KB8 TFREYAIEPATKWHPRGNLAHCYSAEELVHRDCLQAPSAAGVPGDVLAKSSANVYHHP-T
.:. : ...:.: :: : .: .::. : . . : :: .
NP_689 SFQSKATVFGASWNP-------------VH-----AAGANAVPAAVYHHHHHHPYVHPQA
60 70 80 90
120 130 140 150 160 170
pF1KB8 PAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPGDKSAEKGP-PAATATSAA
:.... . :. . : : : : . . : ::..: :. . . .
NP_689 PVAAAAPDGRYMRSWLEPTPGALSFA---GLPSSRPYGIKPEPLSARRGDCPTLDTHTLS
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 AAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPESSSGHTEDKAGGSSG
. : :.: .. . . :. :. : .:. . : . ..: .. :...
NP_689 LTDYACGSPPVDREKQPSEGAFSENNAE-NESGGDKPPIDPNNPAANWLHARS-------
160 170 180 190 200
240 250 260 270 280 290
pF1KB8 QRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK
::::::::::.: :::.::.:..:.....: ...:.::::.::::::::::::: ::
NP_689 --TRKKRCPYTKHQTLELEKEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKK
210 220 230 240 250 260
300 310
pF1KB8 INRDRLQYYSANPLL
::.::
NP_689 INKDRAKDE
270
313 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:37:28 2016 done: Fri Nov 4 16:37:30 2016
Total Scan time: 9.180 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]