Result of FASTA (omim) for
pF1KB8951
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8951, 326 aa
1>>>pF1KB8951 326 - 326 aa - 326 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6767+/-0.000402; mu= 19.1347+/- 0.025
mean_var=87.5994+/-23.948, 0's: 0 Z-trim(111.5): 526 B-trim: 2128 in 2/48
Lambda= 0.137033
statistics sampled from 19329 (20086) to 19329 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.236), width: 16
Scan time: 7.160
The best scores are: opt bits E(85289)
NP_000665 (OMIM: 102775) adenosine receptor A1 [Ho ( 326) 2171 439.7 4e-123
NP_001041695 (OMIM: 102775) adenosine receptor A1 ( 326) 2171 439.7 4e-123
XP_005244958 (OMIM: 102775) PREDICTED: adenosine r ( 258) 1463 299.6 4.7e-81
XP_016855831 (OMIM: 102775) PREDICTED: adenosine r ( 258) 1463 299.6 4.7e-81
XP_005244959 (OMIM: 102775) PREDICTED: adenosine r ( 258) 1463 299.6 4.7e-81
NP_001265426 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_001265429 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_000666 (OMIM: 102776) adenosine receptor A2a [H ( 412) 1015 211.3 2.9e-54
NP_001265427 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_001265428 (OMIM: 102776) adenosine receptor A2a ( 412) 1015 211.3 2.9e-54
NP_000667 (OMIM: 600446) adenosine receptor A2b [H ( 332) 903 189.0 1.2e-47
NP_000668 (OMIM: 600445) adenosine receptor A3 iso ( 318) 859 180.3 4.7e-45
XP_011521961 (OMIM: 600446) PREDICTED: adenosine r ( 229) 566 122.2 1e-27
XP_016879686 (OMIM: 600446) PREDICTED: adenosine r ( 231) 554 119.8 5.4e-27
NP_001289608 (OMIM: 600445) adenosine receptor A3 ( 173) 514 111.8 1.1e-24
NP_001289607 (OMIM: 600445) adenosine receptor A3 ( 123) 377 84.5 1.2e-16
XP_011521963 (OMIM: 600446) PREDICTED: adenosine r ( 116) 349 78.9 5.5e-15
NP_150598 (OMIM: 606665) melanopsin isoform 1 [Hom ( 478) 355 80.9 6e-15
XP_016872445 (OMIM: 606665) PREDICTED: melanopsin ( 528) 355 80.9 6.4e-15
NP_071640 (OMIM: 142703) histamine H2 receptor iso ( 359) 346 78.9 1.7e-14
XP_006714928 (OMIM: 142703) PREDICTED: histamine H ( 362) 346 78.9 1.7e-14
NP_001124527 (OMIM: 142703) histamine H2 receptor ( 397) 346 79.0 1.8e-14
XP_005265961 (OMIM: 142703) PREDICTED: histamine H ( 422) 346 79.0 1.9e-14
XP_011532850 (OMIM: 142703) PREDICTED: histamine H ( 422) 346 79.0 1.9e-14
XP_006714927 (OMIM: 142703) PREDICTED: histamine H ( 422) 346 79.0 1.9e-14
XP_016864915 (OMIM: 142703) PREDICTED: histamine H ( 422) 346 79.0 1.9e-14
XP_011532851 (OMIM: 142703) PREDICTED: histamine H ( 422) 346 79.0 1.9e-14
NP_444508 (OMIM: 606927) trace amine-associated re ( 342) 342 78.1 2.9e-14
NP_778237 (OMIM: 608923) trace amine-associated re ( 345) 333 76.3 1e-13
NP_778227 (OMIM: 608282) trace amine-associated re ( 348) 331 76.0 1.3e-13
NP_071429 (OMIM: 607448) neuropeptide FF receptor ( 430) 329 75.7 2e-13
NP_937822 (OMIM: 606925) pyroglutamylated RFamide ( 431) 327 75.3 2.6e-13
XP_016872446 (OMIM: 606665) PREDICTED: melanopsin ( 405) 322 74.3 5e-13
NP_001025186 (OMIM: 606665) melanopsin isoform 2 [ ( 489) 322 74.4 5.6e-13
XP_016872444 (OMIM: 606665) PREDICTED: melanopsin ( 539) 322 74.4 6e-13
NP_848566 (OMIM: 300513) glucose-dependent insulin ( 335) 317 73.2 8.8e-13
NP_064552 (OMIM: 605108) neuromedin-U receptor 2 [ ( 415) 312 72.3 2e-12
NP_612200 (OMIM: 609333) trace amine-associated re ( 339) 309 71.6 2.6e-12
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 308 71.5 3.4e-12
NP_001035262 (OMIM: 602164) 5-hydroxytryptamine re ( 360) 306 71.0 4.2e-12
NP_955525 (OMIM: 602164) 5-hydroxytryptamine recep ( 378) 306 71.1 4.3e-12
NP_001035259 (OMIM: 602164) 5-hydroxytryptamine re ( 387) 306 71.1 4.3e-12
NP_000861 (OMIM: 602164) 5-hydroxytryptamine recep ( 388) 306 71.1 4.4e-12
NP_000016 (OMIM: 109691,601665) beta-3 adrenergic ( 408) 306 71.1 4.5e-12
NP_001273339 (OMIM: 602164) 5-hydroxytryptamine re ( 411) 306 71.1 4.5e-12
NP_001035263 (OMIM: 602164) 5-hydroxytryptamine re ( 428) 306 71.1 4.6e-12
NP_003958 (OMIM: 607405) trace amine-associated re ( 337) 303 70.4 6e-12
NP_000672 (OMIM: 104210) alpha-2A adrenergic recep ( 465) 303 70.6 7.4e-12
XP_011542714 (OMIM: 104221) PREDICTED: alpha-1A ad ( 308) 294 68.6 1.9e-11
NP_000675 (OMIM: 109630,607276) beta-1 adrenergic ( 477) 296 69.2 2e-11
>>NP_000665 (OMIM: 102775) adenosine receptor A1 [Homo s (326 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 2331.5 bits: 439.7 E(85289): 4e-123
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)
10 20 30 40 50 60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
250 260 270 280 290 300
310 320
pF1KB8 KIWNDHFRCQPAPPIDEDLPEERPDD
::::::::::::::::::::::::::
NP_000 KIWNDHFRCQPAPPIDEDLPEERPDD
310 320
>>NP_001041695 (OMIM: 102775) adenosine receptor A1 [Hom (326 aa)
initn: 2171 init1: 2171 opt: 2171 Z-score: 2331.5 bits: 439.7 E(85289): 4e-123
Smith-Waterman score: 2171; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326)
10 20 30 40 50 60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
250 260 270 280 290 300
310 320
pF1KB8 KIWNDHFRCQPAPPIDEDLPEERPDD
::::::::::::::::::::::::::
NP_001 KIWNDHFRCQPAPPIDEDLPEERPDD
310 320
>>XP_005244958 (OMIM: 102775) PREDICTED: adenosine recep (258 aa)
initn: 1463 init1: 1463 opt: 1463 Z-score: 1576.2 bits: 299.6 E(85289): 4.7e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 213 aa overlap (114-326:46-258)
90 100 110 120 130 140
pF1KB8 ACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
::::::::::::::::::::::::::::::
XP_005 LRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB8 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB8 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB8 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
200 210 220 230 240 250
pF1KB8 PDD
:::
XP_005 PDD
>>XP_016855831 (OMIM: 102775) PREDICTED: adenosine recep (258 aa)
initn: 1463 init1: 1463 opt: 1463 Z-score: 1576.2 bits: 299.6 E(85289): 4.7e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 213 aa overlap (114-326:46-258)
90 100 110 120 130 140
pF1KB8 ACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
::::::::::::::::::::::::::::::
XP_016 LRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB8 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB8 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB8 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
200 210 220 230 240 250
pF1KB8 PDD
:::
XP_016 PDD
>>XP_005244959 (OMIM: 102775) PREDICTED: adenosine recep (258 aa)
initn: 1463 init1: 1463 opt: 1463 Z-score: 1576.2 bits: 299.6 E(85289): 4.7e-81
Smith-Waterman score: 1463; 100.0% identity (100.0% similar) in 213 aa overlap (114-326:46-258)
90 100 110 120 130 140
pF1KB8 ACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
::::::::::::::::::::::::::::::
XP_005 LRGPWRPGVPQRGLSRQLGGRSSHSALLSPRYKMVVTPRRAAVAIAGCWILSFVVGLTPM
20 30 40 50 60 70
150 160 170 180 190 200
pF1KB8 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEV
80 90 100 110 120 130
210 220 230 240 250 260
pF1KB8 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSC
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB8 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEER
200 210 220 230 240 250
pF1KB8 PDD
:::
XP_005 PDD
>>NP_001265426 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1007 init1: 700 opt: 1015 Z-score: 1095.2 bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)
10 20 30 40 50 60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
..:: .:. ::.... ::::: ::: .:. :...: :.::::.::.:::.
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
:.::.:: :. : . : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
:: :: ::.:::..:::::.:::: . ... . . :: . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
::::::. :: :::::. .::..: :.::.. : :. .. ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
:. :::: ::::::.::.:.:::.: : : : :.:: :.: ::..::..::.::..::
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
240 250 260 270 280 290
300 310 320
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
:: :: .: : :
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
300 310 320 330 340 350
>>NP_001265429 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1007 init1: 700 opt: 1015 Z-score: 1095.2 bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)
10 20 30 40 50 60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
..:: .:. ::.... ::::: ::: .:. :...: :.::::.::.:::.
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
:.::.:: :. : . : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
:: :: ::.:::..:::::.:::: . ... . . :: . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
::::::. :: :::::. .::..: :.::.. : :. .. ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
:. :::: ::::::.::.:.:::.: : : : :.:: :.: ::..::..::.::..::
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
240 250 260 270 280 290
300 310 320
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
:: :: .: : :
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
300 310 320 330 340 350
>>NP_000666 (OMIM: 102776) adenosine receptor A2a [Homo (412 aa)
initn: 1007 init1: 700 opt: 1015 Z-score: 1095.2 bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)
10 20 30 40 50 60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
..:: .:. ::.... ::::: ::: .:. :...: :.::::.::.:::.
NP_000 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
:.::.:: :. : . : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_000 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
:: :: ::.:::..:::::.:::: . ... . . :: . : :: :. :.::
NP_000 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
::::::. :: :::::. .::..: :.::.. : :. .. ::.. :::::.
NP_000 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
:. :::: ::::::.::.:.:::.: : : : :.:: :.: ::..::..::.::..::
NP_000 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
240 250 260 270 280 290
300 310 320
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
:: :: .: : :
NP_000 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
300 310 320 330 340 350
>>NP_001265427 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1007 init1: 700 opt: 1015 Z-score: 1095.2 bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)
10 20 30 40 50 60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
..:: .:. ::.... ::::: ::: .:. :...: :.::::.::.:::.
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
:.::.:: :. : . : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
:: :: ::.:::..:::::.:::: . ... . . :: . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
::::::. :: :::::. .::..: :.::.. : :. .. ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
:. :::: ::::::.::.:.:::.: : : : :.:: :.: ::..::..::.::..::
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
240 250 260 270 280 290
300 310 320
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
:: :: .: : :
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
300 310 320 330 340 350
>>NP_001265428 (OMIM: 102776) adenosine receptor A2a [Ho (412 aa)
initn: 1007 init1: 700 opt: 1015 Z-score: 1095.2 bits: 211.3 E(85289): 2.9e-54
Smith-Waterman score: 1015; 51.8% identity (75.9% similar) in 307 aa overlap (10-313:7-313)
10 20 30 40 50 60
pF1KB8 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
..:: .:. ::.... ::::: ::: .:. :...: :.::::.::.:::.
NP_001 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
:.::.:: :. : . : ::..:: ::.::::::..:::::.:::. ..:::::. .::
NP_001 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
:: :: ::.:::..:::::.:::: . ... . . :: . : :: :. :.::
NP_001 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM
120 130 140 150 160 170
190 200 210 220 230
pF1KB8 VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSAS-SGD-PQKYYGKELKIAKSLAL
::::::. :: :::::. .::..: :.::.. : :. .. ::.. :::::.
NP_001 VYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAI
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 ILFLFALSWLPLHILNCITLFCPSC-HKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRV
:. :::: ::::::.::.:.:::.: : : : :.:: :.: ::..::..::.::..::
NP_001 IVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQ
240 250 260 270 280 290
300 310 320
pF1KB8 TFLKIWNDHFRCQPAPPIDEDLPEERPDD
:: :: .: : :
NP_001 TFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERR
300 310 320 330 340 350
326 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:38:35 2016 done: Fri Nov 4 16:38:36 2016
Total Scan time: 7.160 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]