FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8953, 328 aa 1>>>pF1KB8953 328 - 328 aa - 328 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.8741+/-0.000358; mu= 3.2125+/- 0.023 mean_var=291.9929+/-59.998, 0's: 0 Z-trim(123.9): 165 B-trim: 768 in 1/57 Lambda= 0.075056 statistics sampled from 44242 (44443) to 44242 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.521), width: 16 Scan time: 9.350 The best scores are: opt bits E(85289) NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328) 2225 253.5 4.5e-67 XP_005246564 (OMIM: 142987) PREDICTED: homeobox pr ( 270) 1506 175.6 1.1e-43 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 533 70.2 6e-12 NP_005513 (OMIM: 142955,601536) homeobox protein H ( 335) 526 69.5 1.1e-11 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 353 50.9 5.6e-06 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 353 50.9 5.6e-06 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 353 50.9 5.6e-06 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 353 50.9 5.6e-06 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 353 50.9 5.6e-06 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 353 50.9 5.6e-06 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 353 50.9 5.6e-06 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 353 50.9 5.6e-06 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 321 47.2 4.5e-05 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 321 47.2 4.5e-05 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 312 46.3 9.3e-05 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 312 46.3 0.0001 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 309 45.9 0.00011 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 311 46.3 0.00013 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 308 45.9 0.00013 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 307 45.8 0.00015 NP_001795 (OMIM: 600746) homeobox protein CDX-1 [H ( 265) 301 45.1 0.0002 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 297 44.9 0.00038 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 297 44.9 0.00038 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 297 44.9 0.00038 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 297 44.9 0.00038 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 297 44.9 0.00038 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 297 44.9 0.00038 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 297 44.9 0.00038 NP_005512 (OMIM: 186770) T-cell leukemia homeobox ( 330) 293 44.3 0.00043 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 287 43.5 0.00052 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 287 43.5 0.00052 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 287 43.5 0.00052 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 287 43.5 0.00056 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 290 44.0 0.00056 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 287 43.6 0.0006 NP_001182446 (OMIM: 186770) T-cell leukemia homeob ( 257) 285 43.3 0.00066 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 285 43.5 0.00085 NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 284 43.4 0.00097 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 281 43.0 0.00098 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 278 42.5 0.0011 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 281 43.0 0.0011 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 281 43.0 0.0011 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 277 42.4 0.0011 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 281 43.1 0.0012 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 281 43.1 0.0013 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 281 43.1 0.0013 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 281 43.1 0.0013 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 281 43.1 0.0013 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 281 43.1 0.0013 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 281 43.1 0.0013 >>NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [Homo (328 aa) initn: 2225 init1: 2225 opt: 2225 Z-score: 1325.2 bits: 253.5 E(85289): 4.5e-67 Smith-Waterman score: 2225; 99.7% identity (100.0% similar) in 328 aa overlap (1-328:1-328) 10 20 30 40 50 60 pF1KB8 MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 PSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 LGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_078 ASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATTIPVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::.:::: NP_078 LTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATAIPVA 250 260 270 280 290 300 310 320 pF1KB8 PLQLPLSGTTPTKFIKNPGSPSQSQEPS :::::::::::::::::::::::::::: NP_078 PLQLPLSGTTPTKFIKNPGSPSQSQEPS 310 320 >>XP_005246564 (OMIM: 142987) PREDICTED: homeobox protei (270 aa) initn: 1506 init1: 1506 opt: 1506 Z-score: 905.5 bits: 175.6 E(85289): 1.1e-43 Smith-Waterman score: 1506; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217) 10 20 30 40 50 60 pF1KB8 MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAAR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAYDFPGV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQ ::::::::::::::::::::::::::::::::::::: XP_005 ASPAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKDSGLGFVEETRSRANSMESASST 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREGLLATTIPVA XP_005 DSENVPGIEKISGRSSPWNFSWQTRRVWGR 250 260 270 >>NP_002135 (OMIM: 142968,614744) homeobox protein Hox-B (301 aa) initn: 431 init1: 344 opt: 533 Z-score: 335.5 bits: 70.2 E(85289): 6e-12 Smith-Waterman score: 555; 39.9% identity (58.3% similar) in 333 aa overlap (1-322:6-297) 10 20 30 40 50 pF1KB8 MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLP :.:.::: :. : . .. : .: :.:. : . : : : . NP_002 MDYNRMNSFLEYPLCNR-GPSAYSAHSAPTSFPPSSAQAVD-SYASEGRYGGGLSSPAFQ 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSGPAY .. :. .::.. . : : .::. : :::: . .:: :. NP_002 QNSGYPAQQPPSTLGVPF--PSSAPS------------GYAPAACS--PSYG-----PSQ 60 70 80 90 120 130 140 150 160 170 pF1KB8 DFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGE-PGPFPACLKASADGH .: ::.. ::: . : .. .. :: : .: :.: : :::.: : NP_002 YYP--LGQSEGDGG-YFHPSSYGAQLGG---LSDG---YGAGGAGPGPYP-------PQH 100 110 120 130 140 180 190 200 210 220 pF1KB8 P--GAFQTASPAPGTYPKSVS-----PASGLPAAFS--TFEWMKVKRNASKKGKLAEYGA : : :::: ::. : .: : . : . . ::.::::::: : .:..: : NP_002 PPYGNEQTASFAPA-YADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKVSEPGL 150 160 170 180 190 200 230 240 250 260 270 280 pF1KB8 ASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQK .:::. .::::.:.:::::::::::::::.::::.::: :.::.::::::::::::::: NP_002 GSPSG-LRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQK 210 220 230 240 250 290 300 310 320 pF1KB8 KRERE-GLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQSQEPS ::::: : . . : : . ... . . .::: NP_002 KREREEGRVPPAPPGCPKEAAGDASDQSTCTSPEASPSSVTS 260 270 280 290 300 >>NP_005513 (OMIM: 142955,601536) homeobox protein Hox-A (335 aa) initn: 578 init1: 500 opt: 526 Z-score: 330.8 bits: 69.5 E(85289): 1.1e-11 Smith-Waterman score: 536; 37.0% identity (58.7% similar) in 341 aa overlap (1-328:6-328) 10 20 30 40 50 pF1KB8 MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGN---GDGAFVS :.:.::: :: :: . . . :: : ...: .: :: :. NP_005 MDNARMNSFLEYPILSS-----GDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLV 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 CLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSG . . : .:. ::. : . : :.. . .. : .:: . . NP_005 GRGVQIGSPHHHHHHHHHHPQ---PATYQTS-----GNL--GVSYSHSSCGPSYGSQNFS 60 70 80 90 100 120 130 140 150 160 pF1KB8 PAYDFPGVLGRAADDGGSHVHYATSAVFSGG-GSFLLSGQVDYAAF--GEPGPFPACLKA :. : .:.. :: .:.. . : ::.::. .: ... . . .. : : : .. NP_005 APYS-PYALNQEADVSGGYPQCAP-AVYSGNLSSPMVQHHHHHQGYAGGAVGS-PQYIHH 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 SADGHPGAFQTA------SPAPGTYPKSV-SPASGLPAAFSTFEWMKVKRNASKKGKLAE : . .. : :: ... .. :::: . .::.::::::: : ::..: NP_005 SYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGE 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB8 YGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRM :: . .:.::::.::::::::::::::::::::::.::: :.::.:::::::::::: NP_005 YGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRM 230 240 250 260 270 280 290 300 310 320 pF1KB8 KQKKREREGLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQSQEPS ::::::.:::: . . : . . . : ..: :: .. : NP_005 KQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH 290 300 310 320 330 >>XP_005246567 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 371 init1: 261 opt: 353 Z-score: 228.3 bits: 50.9 E(85289): 5.6e-06 Smith-Waterman score: 392; 35.8% identity (58.7% similar) in 254 aa overlap (67-308:44-274) 40 50 60 70 80 90 pF1KB8 LQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAA ..: .: ::::: . .:. : ::.: XP_005 ECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQP-YPPPAAAS----SLDTDY-PGSA 20 30 40 50 60 100 110 120 130 140 150 pF1KB8 PAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAA . ..: .::. ..:. .:: .. .:. .:::. : . XP_005 -CSIQSSAPL----RAPAH-------KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQ 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 FGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFST--FEWMKVKRNA .: : : : :. .::. .:. ::. ::. :..: : ::: .:. XP_005 PPQPPPPPPTLPPSSPTNPGG-----GVPAKKPKGGPNASSSSATISKQIFPWMKESRQN 120 130 140 150 160 170 220 230 240 250 260 pF1KB8 SK-KGKLAEYGAA----SP----SSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANC :: :.. : : . :: :. .:: ... ::.:::::::::.:: : ::.:.:: XP_005 SKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB8 LHLNDTQVKIWFQNRRMKQKKRER-EGLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQS :.:.. :.:::::::::: :: .. .:.: . .: . : : XP_005 LNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVP 240 250 260 270 280 290 pF1KB8 QEPS XP_005 GLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASAN 300 310 320 330 340 350 >>NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [Homo (432 aa) initn: 371 init1: 261 opt: 353 Z-score: 228.3 bits: 50.9 E(85289): 5.6e-06 Smith-Waterman score: 392; 35.8% identity (58.7% similar) in 254 aa overlap (67-308:44-274) 40 50 60 70 80 90 pF1KB8 LQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAA ..: .: ::::: . .:. : ::.: NP_008 ECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQP-YPPPAAAS----SLDTDY-PGSA 20 30 40 50 60 100 110 120 130 140 150 pF1KB8 PAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAA . ..: .::. ..:. .:: .. .:. .:::. : . NP_008 -CSIQSSAPL----RAPAH-------KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQ 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 FGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFST--FEWMKVKRNA .: : : : :. .::. .:. ::. ::. :..: : ::: .:. NP_008 PPQPPPPPPTLPPSSPTNPGG-----GVPAKKPKGGPNASSSSATISKQIFPWMKESRQN 120 130 140 150 160 170 220 230 240 250 260 pF1KB8 SK-KGKLAEYGAA----SP----SSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANC :: :.. : : . :: :. .:: ... ::.:::::::::.:: : ::.:.:: NP_008 SKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB8 LHLNDTQVKIWFQNRRMKQKKRER-EGLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQS :.:.. :.:::::::::: :: .. .:.: . .: . : : NP_008 LNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVP 240 250 260 270 280 290 pF1KB8 QEPS NP_008 GLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASAN 300 310 320 330 340 350 >>XP_011509367 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 371 init1: 261 opt: 353 Z-score: 228.3 bits: 50.9 E(85289): 5.6e-06 Smith-Waterman score: 392; 35.8% identity (58.7% similar) in 254 aa overlap (67-308:44-274) 40 50 60 70 80 90 pF1KB8 LQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAA ..: .: ::::: . .:. : ::.: XP_011 ECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQP-YPPPAAAS----SLDTDY-PGSA 20 30 40 50 60 100 110 120 130 140 150 pF1KB8 PAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAA . ..: .::. ..:. .:: .. .:. .:::. : . XP_011 -CSIQSSAPL----RAPAH-------KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQ 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 FGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFST--FEWMKVKRNA .: : : : :. .::. .:. ::. ::. :..: : ::: .:. XP_011 PPQPPPPPPTLPPSSPTNPGG-----GVPAKKPKGGPNASSSSATISKQIFPWMKESRQN 120 130 140 150 160 170 220 230 240 250 260 pF1KB8 SK-KGKLAEYGAA----SP----SSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANC :: :.. : : . :: :. .:: ... ::.:::::::::.:: : ::.:.:: XP_011 SKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB8 LHLNDTQVKIWFQNRRMKQKKRER-EGLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQS :.:.. :.:::::::::: :: .. .:.: . .: . : : XP_011 LNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVP 240 250 260 270 280 290 pF1KB8 QEPS XP_011 GLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASAN 300 310 320 330 340 350 >>XP_005246566 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 371 init1: 261 opt: 353 Z-score: 228.3 bits: 50.9 E(85289): 5.6e-06 Smith-Waterman score: 392; 35.8% identity (58.7% similar) in 254 aa overlap (67-308:44-274) 40 50 60 70 80 90 pF1KB8 LQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAA ..: .: ::::: . .:. : ::.: XP_005 ECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQP-YPPPAAAS----SLDTDY-PGSA 20 30 40 50 60 100 110 120 130 140 150 pF1KB8 PAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAA . ..: .::. ..:. .:: .. .:. .:::. : . XP_005 -CSIQSSAPL----RAPAH-------KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQ 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 FGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFST--FEWMKVKRNA .: : : : :. .::. .:. ::. ::. :..: : ::: .:. XP_005 PPQPPPPPPTLPPSSPTNPGG-----GVPAKKPKGGPNASSSSATISKQIFPWMKESRQN 120 130 140 150 160 170 220 230 240 250 260 pF1KB8 SK-KGKLAEYGAA----SP----SSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANC :: :.. : : . :: :. .:: ... ::.:::::::::.:: : ::.:.:: XP_005 SKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB8 LHLNDTQVKIWFQNRRMKQKKRER-EGLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQS :.:.. :.:::::::::: :: .. .:.: . .: . : : XP_005 LNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVP 240 250 260 270 280 290 pF1KB8 QEPS XP_005 GLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASAN 300 310 320 330 340 350 >>XP_005246570 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 371 init1: 261 opt: 353 Z-score: 228.3 bits: 50.9 E(85289): 5.6e-06 Smith-Waterman score: 392; 35.8% identity (58.7% similar) in 254 aa overlap (67-308:44-274) 40 50 60 70 80 90 pF1KB8 LQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAA ..: .: ::::: . .:. : ::.: XP_005 ECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQP-YPPPAAAS----SLDTDY-PGSA 20 30 40 50 60 100 110 120 130 140 150 pF1KB8 PAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAA . ..: .::. ..:. .:: .. .:. .:::. : . XP_005 -CSIQSSAPL----RAPAH-------KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQ 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 FGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFST--FEWMKVKRNA .: : : : :. .::. .:. ::. ::. :..: : ::: .:. XP_005 PPQPPPPPPTLPPSSPTNPGG-----GVPAKKPKGGPNASSSSATISKQIFPWMKESRQN 120 130 140 150 160 170 220 230 240 250 260 pF1KB8 SK-KGKLAEYGAA----SP----SSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANC :: :.. : : . :: :. .:: ... ::.:::::::::.:: : ::.:.:: XP_005 SKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB8 LHLNDTQVKIWFQNRRMKQKKRER-EGLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQS :.:.. :.:::::::::: :: .. .:.: . .: . : : XP_005 LNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVP 240 250 260 270 280 290 pF1KB8 QEPS XP_005 GLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASAN 300 310 320 330 340 350 >>XP_011509368 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 371 init1: 261 opt: 353 Z-score: 228.3 bits: 50.9 E(85289): 5.6e-06 Smith-Waterman score: 392; 35.8% identity (58.7% similar) in 254 aa overlap (67-308:44-274) 40 50 60 70 80 90 pF1KB8 LQPAFPLGNGDGAFVSCLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAA ..: .: ::::: . .:. : ::.: XP_011 ECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQP-YPPPAAAS----SLDTDY-PGSA 20 30 40 50 60 100 110 120 130 140 150 pF1KB8 PAAAAGGADYGFLGSGPAYDFPGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAA . ..: .::. ..:. .:: .. .:. .:::. : . XP_011 -CSIQSSAPL----RAPAH-------KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQ 70 80 90 100 110 160 170 180 190 200 210 pF1KB8 FGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFST--FEWMKVKRNA .: : : : :. .::. .:. ::. ::. :..: : ::: .:. XP_011 PPQPPPPPPTLPPSSPTNPGG-----GVPAKKPKGGPNASSSSATISKQIFPWMKESRQN 120 130 140 150 160 170 220 230 240 250 260 pF1KB8 SK-KGKLAEYGAA----SP----SSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANC :: :.. : : . :: :. .:: ... ::.:::::::::.:: : ::.:.:: XP_011 SKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB8 LHLNDTQVKIWFQNRRMKQKKRER-EGLLATTIPVAPLQLPLSGTTPTKFIKNPGSPSQS :.:.. :.:::::::::: :: .. .:.: . .: . : : XP_011 LNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVP 240 250 260 270 280 290 pF1KB8 QEPS XP_011 GLAYDAPSPPAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASAN 300 310 320 330 340 350 328 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:39:45 2016 done: Fri Nov 4 16:39:46 2016 Total Scan time: 9.350 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]