FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8955, 332 aa 1>>>pF1KB8955 332 - 332 aa - 332 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3983+/-0.00111; mu= 15.3968+/- 0.066 mean_var=228.1571+/-116.004, 0's: 0 Z-trim(103.5): 360 B-trim: 872 in 2/50 Lambda= 0.084910 statistics sampled from 6868 (7441) to 6868 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.578), E-opt: 0.2 (0.229), width: 16 Scan time: 2.120 The best scores are: opt bits E(32554) CCDS11173.1 ADORA2B gene_id:136|Hs108|chr17 ( 332) 2200 283.5 1.7e-76 CCDS13826.1 ADORA2A gene_id:135|Hs108|chr22 ( 412) 1274 170.2 2.6e-42 CCDS1434.1 ADORA1 gene_id:134|Hs108|chr1 ( 326) 903 124.6 1.1e-28 CCDS839.1 ADORA3 gene_id:140|Hs108|chr1 ( 318) 462 70.5 2e-12 >>CCDS11173.1 ADORA2B gene_id:136|Hs108|chr17 (332 aa) initn: 2200 init1: 2200 opt: 2200 Z-score: 1487.1 bits: 283.5 E(32554): 1.7e-76 Smith-Waterman score: 2200; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332) 10 20 30 40 50 60 pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT 250 260 270 280 290 300 310 320 330 pF1KB8 FHKIISRYLLCQADVKSGNGQAGVQPALGVGL :::::::::::::::::::::::::::::::: CCDS11 FHKIISRYLLCQADVKSGNGQAGVQPALGVGL 310 320 330 >>CCDS13826.1 ADORA2A gene_id:135|Hs108|chr22 (412 aa) initn: 1234 init1: 824 opt: 1274 Z-score: 873.2 bits: 170.2 E(32554): 2.6e-42 Smith-Waterman score: 1274; 59.4% identity (82.1% similar) in 330 aa overlap (8-329:7-328) 10 20 30 40 50 60 pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA ..:...::.::.:.. :::::: :: ..::. ::::.:::::::.:::..: CCDS13 MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLA 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT :::::::: :::. .::::.:::::::::::::::::.:.:::.:: .::::..::::: CCDS13 IPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGT 60 70 80 90 100 110 130 140 150 160 170 pF1KB8 RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCC---LVKCLFENVV ::.:.::. :::.:.:::::.:::: :: .: .: .. . : : ::::.:: CCDS13 RAKGIIAICWVLSFAIGLTPMLGWN-------NCGQPKEGKNHSQGCGEGQVACLFEDVV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELM----DHSRTTLQREIHAA ::.::::::::.::: :::.:: .:..:::.: :::.. : . ...:.:::.:.::: CCDS13 PMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAA 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 KSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYR ::::.:::.:::::::.: .:: :.: : . .. : : : .::.:::.::::::..:::: CCDS13 KSLAIIVGLFALCWLPLHIINCFTFFCP-DCSHAPLWLMYLAIVLSHTNSVVNPFIYAYR 240 250 260 270 280 290 300 310 320 330 pF1KB8 NRDFRYTFHKIISRYLLCQAD-VKSGNGQAGVQPALGVGL :.:: ::.::: ..: : . :... .: : : : CCDS13 IREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSA 300 310 320 330 340 350 CCDS13 PHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGV 360 370 380 390 400 410 >>CCDS1434.1 ADORA1 gene_id:134|Hs108|chr1 (326 aa) initn: 740 init1: 472 opt: 903 Z-score: 628.5 bits: 124.6 E(32554): 1.1e-28 Smith-Waterman score: 903; 48.5% identity (74.6% similar) in 307 aa overlap (8-312:10-310) 10 20 30 40 50 pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGL : :...:..:: .:: ::::: :: . ..:. : :.::::.:::::: CCDS14 MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 FAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVT ..::.:: :..: : :. ::..:: ::.::::::..:::.:::::: . .::::: .:: CCDS14 LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 GTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVP :: .:: :.:.: .::::..:::. ::.. . : .. . . ..:: ::.:. CCDS14 PRRAAVAIAGCWILSFVVGLTPMFGWNNL-SAVE---RAWAANGSMGEPVIKCEFEKVIS 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 MSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQR--TELMDHSRTTLQREIHAAKSL : :::::::: ::::::.:..::...: . .::.. . . .:.. :::: CCDS14 MEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSL 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 AMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRD :.:. .::: :::.: .::.::: :. .::. .::.:.:.::..::::::.: . CCDS14 ALILFLFALSWLPLHILNCITLFCPSC--HKPSILTYIAIFLTHGNSAMNPIVYAFRIQK 240 250 260 270 280 290 300 310 320 330 pF1KB8 FRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL :: :: :: . .. :: CCDS14 FRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD 300 310 320 >>CCDS839.1 ADORA3 gene_id:140|Hs108|chr1 (318 aa) initn: 740 init1: 452 opt: 462 Z-score: 336.6 bits: 70.5 E(32554): 2e-12 Smith-Waterman score: 766; 39.3% identity (71.9% similar) in 313 aa overlap (3-312:8-304) 10 20 30 40 50 pF1KB8 MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVA : .. :...:. :. ...::::: .: .::: : ::.:::: ::.: CCDS83 MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 VGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKS ::....:.::..:::. ::.:::..:..:..:..::.::::.:::::: . . .::: CCDS83 VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 LVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFEN ..: : .... :...: .::::..::: : .. . .. ...: : . CCDS83 VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYH----------RNVTFLSCQFVS 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 VVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTT---LQREIHA :. :.:::::.:. .. ::..: .::. :: . .:. . ...:. : ::... CCDS83 VMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLN--LSNSKETGAFYGREFKT 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 AKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAY :::: ... .::: :::. .::. :. :. :. .. :.::::::::..::::::: CCDS83 AKSLFLVLFLFALSWLPLSIINCIIYFN---GEV-PQLVLYMGILLSHANSMMNPIVYAY 230 240 250 260 270 280 300 310 320 330 pF1KB8 RNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL . . :. :. :.. ..:. CCDS83 KIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE 290 300 310 332 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:40:17 2016 done: Fri Nov 4 16:40:17 2016 Total Scan time: 2.120 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]