FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8956, 333 aa 1>>>pF1KB8956 333 - 333 aa - 333 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1248+/-0.000724; mu= 9.6800+/- 0.044 mean_var=155.4916+/-32.222, 0's: 0 Z-trim(114.8): 167 B-trim: 853 in 1/49 Lambda= 0.102854 statistics sampled from 15163 (15338) to 15163 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.787), E-opt: 0.2 (0.471), width: 16 Scan time: 2.340 The best scores are: opt bits E(32554) CCDS3410.1 2 gene_id:579|Hs108|chr4 ( 333) 2213 339.5 2.3e-93 CCDS41558.1 3 gene_id:159296|Hs108|chr10 ( 364) 384 68.1 1.2e-11 CCDS59095.1 1 gene_id:4824|Hs108|chr8 ( 159) 367 65.3 3.9e-11 CCDS6042.1 1 gene_id:4824|Hs108|chr8 ( 234) 367 65.4 5.1e-11 CCDS41575.1 HMX3 gene_id:340784|Hs108|chr10 ( 357) 368 65.7 6.3e-11 CCDS4387.1 5 gene_id:1482|Hs108|chr5 ( 324) 364 65.1 8.9e-11 >>CCDS3410.1 2 gene_id:579|Hs108|chr4 (333 aa) initn: 2213 init1: 2213 opt: 2213 Z-score: 1789.6 bits: 339.5 E(32554): 2.3e-93 Smith-Waterman score: 2213; 100.0% identity (100.0% similar) in 333 aa overlap (1-333:1-333) 10 20 30 40 50 60 pF1KB8 MAVRGANTLTSFSIQAILNKKEERGGLAAPEGRPAPGGTAASVAAAPAVCCWRLFGERDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 MAVRGANTLTSFSIQAILNKKEERGGLAAPEGRPAPGGTAASVAAAPAVCCWRLFGERDA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 GALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENESRRRCADARGASGAGLAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 GSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDDGVGPRGAHVSALCSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 AGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 AGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLA 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 ASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS34 ASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLR 250 260 270 280 290 300 310 320 330 pF1KB8 PPSLLPLQPSYYYPYYCLPGWALSTCAAAAGTQ ::::::::::::::::::::::::::::::::: CCDS34 PPSLLPLQPSYYYPYYCLPGWALSTCAAAAGTQ 310 320 330 >>CCDS41558.1 3 gene_id:159296|Hs108|chr10 (364 aa) initn: 295 init1: 295 opt: 384 Z-score: 322.4 bits: 68.1 E(32554): 1.2e-11 Smith-Waterman score: 384; 49.0% identity (68.7% similar) in 147 aa overlap (190-330:131-274) 160 170 180 190 200 210 pF1KB8 PRTEDDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRS-RAAFSHAQV :: . :: ::::..:. :. ::.::: CCDS41 CSEPKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQV 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB8 FELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASA---- :::::::..:::::.::: ::.::::: ::::::::::::: ::... .: .: CCDS41 FELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPP 170 180 190 200 210 220 280 290 300 310 320 330 pF1KB8 PAAKKVAVKVLVRDDQRQYLPG-EVLRPPSLLPLQPSYYYPYYCLPGWALSTCAAAAGTQ : ..::: ::::: . :. .. : . . : : .:... .. :::: CCDS41 PPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASA---YSYNSFPAYGYGNSAAAAAAA 230 240 250 260 270 CCDS41 AAAAAAAAAYSSSYGCAYPAGGGGGGGGTSAATTAMQPACSAAGGGPFVNVSNLGGFGSG 280 290 300 310 320 330 >>CCDS59095.1 1 gene_id:4824|Hs108|chr8 (159 aa) initn: 440 init1: 355 opt: 367 Z-score: 313.5 bits: 65.3 E(32554): 3.9e-11 Smith-Waterman score: 392; 53.2% identity (72.2% similar) in 126 aa overlap (199-322:42-155) 170 180 190 200 210 220 pF1KB8 PRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQ : .:: .:::::::::.::.::::.:.:: CCDS59 AETLAETEPERHLGSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQ 20 30 40 50 60 70 230 240 250 260 270 280 pF1KB8 RYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAADLLASAPAAKKVAVKVLVRD .:::.:::: :: .:::::::::::::::::::::.:....: : . CCDS59 KYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGD------------LEKH 80 90 100 110 290 300 310 320 330 pF1KB8 DQRQYLPGEVLRPPSLLPLQPSY-YYPY-YCLPGWALSTCAAAAGTQ .. : :.. ::. . :: :::: ::. .:. CCDS59 SSLPALKEEAFSRASLVSVYNSYPYYPYLYCVGSWSPAFW 120 130 140 150 >>CCDS6042.1 1 gene_id:4824|Hs108|chr8 (234 aa) initn: 480 init1: 355 opt: 367 Z-score: 311.2 bits: 65.4 E(32554): 5.1e-11 Smith-Waterman score: 396; 39.6% identity (62.3% similar) in 212 aa overlap (136-322:32-230) 110 120 130 140 150 160 pF1KB8 RCADARGASGAGLAGGSLSLGQPVCELAASKDLEEEAAGRSDSEMSASVSGDRSPRTEDD .:. ...: :. .. :.. . : :. : . CCDS60 LRVPEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPE 10 20 30 40 50 60 170 180 190 200 pF1KB8 GVGPR---GAHVSALCSGAGGGGGSGPAGVAEEEEE--------------------PAAP : : ::. . : .: .. . . .:: : : : .: CCDS60 PEGGRSRAGAQNDQLSTGPRAAPEEAET-LAETEPERHLGSYLLDSENTSGALPRLPQTP 70 80 90 100 110 120 210 220 230 240 250 260 pF1KB8 KPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTK : .:::::::::.::.::::.:.::.:::.:::: :: .:::::::::::::::::::: CCDS60 KQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTK 130 140 150 160 170 180 270 280 290 300 310 320 pF1KB8 RRQMAADLLASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSY-YYPY-YCLPG :.:....: . :. .. .: . :.. ::. . :: :::: ::. . CCDS60 RKQLSSEL---GDLEKHSSLPALKE---------EAFSRASLVSVYNSYPYYPYLYCVGS 190 200 210 220 330 pF1KB8 WALSTCAAAAGTQ :. CCDS60 WSPAFW 230 >>CCDS41575.1 HMX3 gene_id:340784|Hs108|chr10 (357 aa) initn: 375 init1: 271 opt: 368 Z-score: 309.6 bits: 65.7 E(32554): 6.3e-11 Smith-Waterman score: 368; 33.0% identity (55.5% similar) in 330 aa overlap (10-319:29-346) 10 20 30 pF1KB8 MAVRGANTLTSFSIQAILNKKEERGGLAAPEGRPAP----- . :::. .:: ..: :. .: : CCDS41 MPEPGPDAAGTASAQPQPPPPPPPAPKESPFSIKNLLNGDHHR---PPPKPQPPPRTLFA 10 20 30 40 50 40 50 60 70 80 pF1KB8 GGTAASVAAAPAVCCWRLFGERDAG-ALGGAEDSLLASP----AGTRTA--AGRTAESPE ..::..::: :. . : :: ::. . : :: : . : : : .:: CCDS41 PASAAAAAAAAAAAAAKGALEGAAGFALSQVGD--LAFPRFEIPAQRFALPAHYLERSPA 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB8 GWDSDSALSEENESRRRCADARGASGAGLAGGSLSLGQPVCELAASKDLEEEAAGRSDSE : . .. : :. .. . ... . .: : :. : ..: ..: .: CCDS41 WWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPD-HKELDSKSPDE 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB8 MSASVSGDRSPRTEDDGV-GPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKR . : .. . : ... : :: :.: ..: :. . :. :..:: :::. CCDS41 IILEESDSEESKKEGEAAPGAAGASVGA--AAATPGAEDWKKGAESPEKKPAC---RKKK 180 190 200 210 220 210 220 230 240 250 260 pF1KB8 SRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKRRQMAA .:..::..:::.:: :. .::::. ::: :::::.:::::::::::::: : :: :.:: CCDS41 TRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKR-QLAA 230 240 250 260 270 280 270 280 290 300 310 320 pF1KB8 DL----LASAPAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYYYP---YYCLPGW .: :. : : . : : .: .... . . . :: .: :: : CCDS41 ELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQPLLTFPHPVYYSHPVV 290 300 310 320 330 340 330 pF1KB8 ALSTCAAAAGTQ CCDS41 SSVPLLRPV 350 >>CCDS4387.1 5 gene_id:1482|Hs108|chr5 (324 aa) initn: 364 init1: 265 opt: 364 Z-score: 307.0 bits: 65.1 E(32554): 8.9e-11 Smith-Waterman score: 364; 46.9% identity (65.7% similar) in 143 aa overlap (194-327:123-265) 170 180 190 200 210 220 pF1KB8 DDGVGPRGAHVSALCSGAGGGGGSGPAGVAEEEEEPAAPKPRKKRSRAA---FSHAQVFE :. : : .:: .: : ::.:::.: CCDS43 YPRAYSDPDPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYE 100 110 120 130 140 150 230 240 250 260 270 pF1KB8 LERRFNHQRYLSGPERADLAASLKLTETQVKIWFQNRRYKTKR-RQ-MAADLLA----SA :::::..:::::.::: .::. :::: ::::::::::::: :: :: .. .:.. CCDS43 LERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKRQRQDQTLELVGLPPPPP 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB8 PAAKKVAVKVLVRDDQRQYLPGEVLRPPSLLPLQPSYYYPYYCLPGWALSTCAAAAGTQ : :...:: ::::: . . : . :.: : : ::.. ..:. CCDS43 PPARRIAVPVLVRDGKPCLGDSAPYAPAYGVGLNPYGYNAYPAYPGYGGAACSPGYSCTA 220 230 240 250 260 270 CCDS43 AYPAGPSPAQPATAAANNNFVNFGVGDLNAVQSPGIPQSNSGVSTLHGIRAW 280 290 300 310 320 333 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:48:30 2016 done: Sat Nov 5 00:48:30 2016 Total Scan time: 2.340 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]