FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8958, 335 aa 1>>>pF1KB8958 335 - 335 aa - 335 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5476+/-0.000322; mu= 12.5662+/- 0.020 mean_var=165.7736+/-33.816, 0's: 0 Z-trim(120.9): 273 B-trim: 28 in 1/58 Lambda= 0.099613 statistics sampled from 36346 (36666) to 36346 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.43), width: 16 Scan time: 8.850 The best scores are: opt bits E(85289) NP_005513 (OMIM: 142955,601536) homeobox protein H ( 335) 2317 344.5 1.9e-94 NP_705873 (OMIM: 142955,601536) homeobox protein H ( 137) 846 132.7 4.5e-31 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 625 101.3 2.7e-21 NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [ ( 328) 525 87.0 6.1e-17 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 338 60.0 6.5e-09 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 338 60.0 6.5e-09 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 331 59.0 1.3e-08 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 323 57.8 2.8e-08 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 321 57.5 3.4e-08 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 317 57.1 6.4e-08 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 313 56.5 8.9e-08 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 309 55.9 1.3e-07 NP_001256 (OMIM: 600297) homeobox protein CDX-2 [H ( 313) 304 55.2 2.2e-07 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 295 53.8 4.8e-07 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 289 52.9 7.7e-07 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 289 52.9 8.3e-07 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 287 52.6 9.7e-07 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 290 53.4 1.1e-06 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 285 52.3 1.1e-06 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 285 52.3 1.1e-06 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 285 52.3 1.1e-06 NP_000200 (OMIM: 125853,260370,600733,606176,60639 ( 283) 285 52.4 1.3e-06 XP_011523029 (OMIM: 142961) PREDICTED: homeobox pr ( 288) 285 52.4 1.4e-06 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 52.9 1.5e-06 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 52.9 1.5e-06 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 287 52.9 1.5e-06 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 52.9 1.5e-06 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 287 52.9 1.5e-06 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 52.9 1.5e-06 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 287 52.9 1.5e-06 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 286 52.7 1.5e-06 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 285 52.6 1.8e-06 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 285 52.6 1.8e-06 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 285 52.6 1.8e-06 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 285 52.6 1.8e-06 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 285 52.6 1.8e-06 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 285 52.6 1.8e-06 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 285 52.6 1.8e-06 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 285 52.6 1.8e-06 NP_004494 (OMIM: 142972) homeobox protein Hox-C6 i ( 235) 280 51.6 2e-06 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 278 51.3 2.3e-06 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 279 51.6 2.5e-06 NP_710160 (OMIM: 142972) homeobox protein Hox-C6 i ( 153) 274 50.5 2.7e-06 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 279 51.7 2.8e-06 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 279 51.7 2.8e-06 NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 279 51.7 2.9e-06 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 279 51.8 3.2e-06 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 279 51.8 3.2e-06 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 279 51.8 3.2e-06 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 279 51.8 3.2e-06 >>NP_005513 (OMIM: 142955,601536) homeobox protein Hox-A (335 aa) initn: 2317 init1: 2317 opt: 2317 Z-score: 1816.8 bits: 344.5 E(85289): 1.9e-94 Smith-Waterman score: 2317; 100.0% identity (100.0% similar) in 335 aa overlap (1-335:1-335) 10 20 30 40 50 60 pF1KB8 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 SPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 SPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 LTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATP 250 260 270 280 290 300 310 320 330 pF1KB8 PGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH ::::::::::::::::::::::::::::::::::: NP_005 PGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH 310 320 330 >>NP_705873 (OMIM: 142955,601536) homeobox protein Hox-A (137 aa) initn: 846 init1: 846 opt: 846 Z-score: 678.9 bits: 132.7 E(85289): 4.5e-31 Smith-Waterman score: 846; 100.0% identity (100.0% similar) in 118 aa overlap (1-118:1-118) 10 20 30 40 50 60 pF1KB8 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLVGRGVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_705 IGSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADPP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 GGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSL NP_705 RSLSLPRIGDIFSSADF 130 >>NP_002135 (OMIM: 142968,614744) homeobox protein Hox-B (301 aa) initn: 614 init1: 377 opt: 625 Z-score: 503.2 bits: 101.3 E(85289): 2.7e-21 Smith-Waterman score: 731; 45.9% identity (67.1% similar) in 340 aa overlap (1-328:1-301) 10 20 30 40 50 pF1KB8 MDNARMNSFLEYPILSSGDSGTCSARAYPSDHRITTFQ-SCAVSANSCGGDDRFLVGRGV :: :::::::::. . : :. ::.. : :.: : : ...: ... :. : : NP_002 MDYNRMNSFLEYPLCNRGPSAY-SAHSAP-----TSFPPSSAQAVDSYASEGRY--GGG- 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 QIGSPHHHHHHHHHHPQPAT-----YQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALN ..:: ... . :: . . .:. : :. ..:.:::: : . : :. NP_002 -LSSPAFQQNSGYPAQQPPSTLGVPFPSSAPSG--YAPAACSPSYG------PSQYYPLG 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 Q-EADVSGGYPQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYI--HHSYGQEHQSL : :.: ::: . :. :...:.. .::..:..: : : ::.:. . NP_002 QSEGD--GGYFH--PSSYGAQLGG-------LSDGYGAGGAGPGPYPPQHPPYGNEQTAS 110 120 130 140 150 180 190 200 210 220 230 pF1KB8 ALATYNNSLSPLHASHQEACRSPASETSSP-AQTFDWMKVKRNPPKTGKVGEYGYLGQPN .: . :: ... : : :: ..: :.::::::::::::::.::.: : ::.:. NP_002 FAPAYADLLS---EDKETPC--P-SEPNTPTARTFDWMKVKRNPPKTAKVSEPG-LGSPS 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 AVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE ..::::::.:::::::::::::::.:::::::::.:.:::::::::::::::::::::.: NP_002 GLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKRERE 210 220 230 240 250 260 300 310 320 330 pF1KB8 -GLLPISPATPPGND-EKAEESSEKSSSSPCVPSPGSSTSDTLTTSH : .: :: ::: : : ..:..:. . ::.: :: NP_002 EGRVP--PA-PPGCPKEAAGDASDQSTCTSPEASPSSVTS 270 280 290 300 >>NP_078777 (OMIM: 142987) homeobox protein Hox-D1 [Homo (328 aa) initn: 535 init1: 499 opt: 525 Z-score: 425.1 bits: 87.0 E(85289): 6.1e-17 Smith-Waterman score: 535; 37.0% identity (58.7% similar) in 341 aa overlap (6-328:1-328) 10 20 30 40 50 pF1KB8 MDNARMNSFLEYPILSS-----GDSGTCSARAYPSDHRITTFQSCAVSANSCGGDDRFLV :.:.::: :: :: . . . :: : ...: .: :: :. NP_078 MSSYLEYVSCSSSGGVGGDVLSLAPKFCRSDARPVALQPAFPLGN---GDGAFVS 10 20 30 40 50 60 70 80 90 100 pF1KB8 GRGVQIGSPHHHHHHHHHHPQ---PATYQTS-----GNL--GVSYSHSSCGPSYGSQNFS . . : .:. ::. : . : :.. . .. : .:: . . NP_078 CLPLAAARPSPSPPAAPARPSVPPPAAPQYAQCTLEGAYEPGAAPAAAAGGADYGFLGSG 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 APYS-PYALNQEADVSGGYPQCAP-AVYSGNLSSPMVQHHHHHQGYAGGAVGS-PQYIHH :. : .:.. :: .:.. . : ::.::. .: ... . . .. : : : .. NP_078 PAYDFPGVLGRAADDGGSHVHYATSAVFSGG-GSFLLSGQVDYAAF--GEPGPFPACLKA 120 130 140 150 160 170 180 190 200 210 220 pF1KB8 SYGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGE : . .. : :: ... .. :::: . .::.::::::: : ::..: NP_078 SADGHPGAFQTA------SPAPGTYPKSV-SPASGLPAAFSTFEWMKVKRNASKKGKLAE 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB8 YGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRM :: . .:.::::.::::::::::::::::::::::.::: :.::.:::::::::::: NP_078 YGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRM 230 240 250 260 270 280 290 300 310 320 330 pF1KB8 KQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH ::::::.:::: . . : . . . : ..: :: .. : NP_078 KQKKREREGLLATAIPVAPLQLPLSGTTPTKFIKNPGSPSQSQEPS 290 300 310 320 >>NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 397 init1: 260 opt: 338 Z-score: 281.0 bits: 60.0 E(85289): 6.5e-09 Smith-Waterman score: 338; 36.3% identity (53.5% similar) in 215 aa overlap (101-302:24-229) 80 90 100 110 120 pF1KB8 HHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAP-YSP--YALNQEADVSGGYPQCA ::: : .:: :. ..:. . . . NP_055 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELY 10 20 30 40 50 130 140 150 160 170 180 pF1KB8 PAVYSGNLSSPMVQHHHHHQGYAGGAVG-SPQYIHHSYGQEHQSLA----LATYNNSLSP : : : :. :.. : .: : . .. ::: :. . : :: NP_055 PPP-PPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSP 60 70 80 90 100 110 190 200 210 220 230 pF1KB8 LH-ASHQEACRSPASETSSPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTNFT : : : :.: .:. .. ::: . :: .: :.:. :: .: NP_055 APPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNG--------GEPKRSRTAYT 120 130 140 150 160 240 250 260 270 280 290 pF1KB8 TKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISP .:. :::::::.:.:::: ::.::: :: :.: :.:::::::::: :: .. . NP_055 RQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRS 170 180 190 200 210 220 300 310 320 330 pF1KB8 ATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH : : : NP_055 APPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 230 240 250 260 >>NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [Homo (264 aa) initn: 397 init1: 260 opt: 338 Z-score: 281.0 bits: 60.0 E(85289): 6.5e-09 Smith-Waterman score: 338; 36.3% identity (53.5% similar) in 215 aa overlap (101-302:24-229) 80 90 100 110 120 pF1KB8 HHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAP-YSP--YALNQEADVSGGYPQCA ::: : .:: :. ..:. . . . NP_705 MIMSSYLMDSNYIDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELY 10 20 30 40 50 130 140 150 160 170 180 pF1KB8 PAVYSGNLSSPMVQHHHHHQGYAGGAVG-SPQYIHHSYGQEHQSLA----LATYNNSLSP : : : :. :.. : .: : . .. ::: :. . : :: NP_705 PPP-PPRPSYPERQYSCTSLQGPGNSRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSP 60 70 80 90 100 110 190 200 210 220 230 pF1KB8 LH-ASHQEACRSPASETSSPAQTFDWMKVKR----NPPKTGKVGEYGYLGQPNAVRTNFT : : : :.: .:. .. ::: . :: .: :.:. :: .: NP_705 APPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNG--------GEPKRSRTAYT 120 130 140 150 160 240 250 260 270 280 290 pF1KB8 TKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISP .:. :::::::.:.:::: ::.::: :: :.: :.:::::::::: :: .. . NP_705 RQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPNTKVRS 170 180 190 200 210 220 300 310 320 330 pF1KB8 ATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH : : : NP_705 APPAGAAPSTLSAATPGTSEDHSQSATPPEQQRAEDITRL 230 240 250 260 >>NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [Homo (270 aa) initn: 323 init1: 257 opt: 331 Z-score: 275.4 bits: 59.0 E(85289): 1.3e-08 Smith-Waterman score: 331; 30.8% identity (52.9% similar) in 263 aa overlap (47-298:10-264) 20 30 40 50 60 70 pF1KB8 SGDSGTCSARAYPSDHRITTFQSCAVSANSCG----GDDRFLVGRGVQIGSPHHHHHHHH :: : : : . : . . .. . NP_061 MSSYFVNSFCGRYPNGPDYQLHNYGDHSSVSEQFRDSAS 10 20 30 80 90 100 110 120 pF1KB8 HHPQPATYQTSG-NLGVSYS---HSSCGP---SYGSQNFSAPYSPYALNQEADVSGGYPQ : : .: .:.:. : : . : ::... .:: : .: : .: :: NP_061 MHSGRYGYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPR-YSQPA-TSTHSPQ 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 CAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHA : :. :: . :: .. ... :. .. . ..... :. . .: . NP_061 PDPLPCSAVAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 SHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE . : :. . : . ::. . . ..: : :. .:: .: : ::: NP_061 EQASAQSEPSPAPPAQPQIYPWMR--KLHISHDNIG--GPEGK--RARTAYTRYQTLELE 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE ::::::.:::: ::.::: .: :.: :.:::::::::: :: .: . .. : NP_061 KEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGAFRP 220 230 240 250 260 270 310 320 330 pF1KB8 KAEESSEKSSSSPCVPSPGSSTSDTLTTSH >>NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [Homo (255 aa) initn: 315 init1: 264 opt: 323 Z-score: 269.5 bits: 57.8 E(85289): 2.8e-08 Smith-Waterman score: 332; 34.8% identity (54.2% similar) in 227 aa overlap (99-322:37-238) 70 80 90 100 110 120 pF1KB8 HHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQCAP ::. .: ..: .: . : : : NP_055 MVNSKYVDPKFPPCEEYLQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDF-GEQP---- 10 20 30 40 50 60 130 140 150 160 170 180 pF1KB8 AVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHASHQ ..:. .: . .: :. :. :.. : : : .: : NP_055 --FGGSGPGPGSALPARGHGQEPGGPGG----HYAAPGEPCPAPPAPPPAPLPGARAYSQ 70 80 90 100 110 190 200 210 220 230 240 pF1KB8 EACRSPASETS--SPAQTFDWMK-VKRNPPKTGKVGEYGYLGQPNAVRTNFTTKQLTELE ..: : :. .:: .. ::: :. : . . .: :.:. :: .: .:. ::: NP_055 SDPKQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTG-----GEPKRSRTAYTRQQVLELE 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB8 KEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDE ::::::.:::: ::.::: .: :.: :.:::::::::: :: .: : . . NP_055 KEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHK---------LPNTKGR 180 190 200 210 220 310 320 330 pF1KB8 KAEESSEKSSSSPCVPSPGSSTSDTLTTSH .. :: .: :: .:: NP_055 SSSSSSSSSCSSSVAPSQHLQPMAKDHHTDLTTL 230 240 250 >>XP_005257332 (OMIM: 142967) PREDICTED: homeobox protei (247 aa) initn: 304 init1: 304 opt: 321 Z-score: 268.1 bits: 57.5 E(85289): 3.4e-08 Smith-Waterman score: 321; 47.9% identity (68.4% similar) in 117 aa overlap (208-322:12-127) 180 190 200 210 220 230 pF1KB8 NSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRNPPKTGKVG--EYGYLGQPNAVRTN .. .: ::.. .: : : : .:: XP_005 MLCPDPGRGCRLERERRKPKSNGLGLPEAGG-GGARRLRTA 10 20 30 40 240 250 260 270 280 290 pF1KB8 FTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPI .:. :: :::::::::::: : ::::::: :.:.: :::.::::::::.:.. .. : XP_005 YTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPD 50 60 70 80 90 100 300 310 320 330 pF1KB8 SPATPPGNDEKAEESSEKSSSSPCVPSPGSSTSDTLTTSH . . :: : . .:. ..:: :: XP_005 GEPACPGALEDICDPAEEPAASPGGPSASRAAWEACCHPPEVVPGALSADPRPLAVRLEG 110 120 130 140 150 160 >>NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [Homo (356 aa) initn: 350 init1: 304 opt: 317 Z-score: 263.2 bits: 57.1 E(85289): 6.4e-08 Smith-Waterman score: 327; 42.5% identity (58.8% similar) in 153 aa overlap (194-322:84-236) 170 180 190 200 210 pF1KB8 YGQEHQSLALATYNNSLSPLHASHQEACRSPASETSSPAQTFDWMKVKRN---P------ : .. :: : ::: :.. : NP_002 PSLQPGASTLQRPRSQKRAEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATS 60 70 80 90 100 110 220 230 240 250 pF1KB8 --PKTGKVGEYGY------LGQPNA-------VRTNFTTKQLTELEKEFHFNKYLTRARR : .. : : :: :.: .:: .:. :: :::::::::::: : :: NP_002 PSPAASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRR 120 130 140 150 160 170 260 270 280 290 300 310 pF1KB8 VEIAASLQLNETQVKIWFQNRRMKQKKREKEGLLPISPATPPGNDEKAEESSEKSSSSPC ::::: :.:.: :::.::::::::.:.. .. : . . :: : . .:. ..:: NP_002 VEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALEDICDPAEEPAASPG 180 190 200 210 220 230 320 330 pF1KB8 VPSPGSSTSDTLTTSH :: NP_002 GPSASRAAWEACCHPPEVVPGALSADPRPLAVRLEGAGASSPGCALRGAGGLEPGPLPED 240 250 260 270 280 290 335 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:40:54 2016 done: Fri Nov 4 16:40:56 2016 Total Scan time: 8.850 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]