FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8961, 342 aa 1>>>pF1KB8961 342 - 342 aa - 342 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0699+/-0.000395; mu= -1.1501+/- 0.025 mean_var=449.4317+/-89.631, 0's: 0 Z-trim(125.4): 112 B-trim: 0 in 0/60 Lambda= 0.060498 statistics sampled from 48982 (49115) to 48982 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.832), E-opt: 0.2 (0.576), width: 16 Scan time: 9.200 The best scores are: opt bits E(85289) NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [ ( 352) 2363 219.7 7.5e-57 NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [ ( 260) 531 59.6 8.5e-09 NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [ ( 272) 510 57.8 3.1e-08 NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [ ( 250) 475 54.7 2.5e-07 NP_002139 (OMIM: 142984,192950) homeobox protein H ( 340) 439 51.7 2.6e-06 NP_061824 (OMIM: 142957) homeobox protein Hox-A10 ( 410) 422 50.4 8.2e-06 NP_059105 (OMIM: 605560) homeobox protein Hox-C10 ( 342) 404 48.7 2.2e-05 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 364 45.1 0.00021 NP_005514 (OMIM: 142958,605432) homeobox protein H ( 313) 349 43.8 0.00058 NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [ ( 230) 340 42.9 0.00082 NP_067015 (OMIM: 142986) homeobox protein Hox-D11 ( 338) 343 43.4 0.00087 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 338 42.7 0.00094 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 332 42.3 0.0015 NP_055027 (OMIM: 605559) homeobox protein Hox-C11 ( 304) 330 42.2 0.0018 NP_005506 (OMIM: 142994,176450) motor neuron and p ( 401) 321 41.5 0.0036 XP_005257343 (OMIM: 142963) PREDICTED: homeobox pr ( 242) 314 40.6 0.0041 XP_016880053 (OMIM: 142963) PREDICTED: homeobox pr ( 243) 313 40.6 0.0044 NP_076921 (OMIM: 142963) homeobox protein Hox-B8 [ ( 243) 313 40.6 0.0044 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 312 40.4 0.0044 NP_073149 (OMIM: 142970) homeobox protein Hox-C8 [ ( 242) 311 40.4 0.0049 NP_000513 (OMIM: 140000,142959,176305) homeobox pr ( 388) 309 40.5 0.0074 XP_011533177 (OMIM: 600297) PREDICTED: homeobox pr ( 321) 304 39.9 0.0089 XP_005257340 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 300 39.4 0.0091 NP_061825 (OMIM: 142961) homeobox protein Hox-B6 [ ( 224) 300 39.4 0.0091 XP_005257341 (OMIM: 142961) PREDICTED: homeobox pr ( 224) 300 39.4 0.0091 NP_004518 (OMIM: 214300,600147) homeobox protein M ( 254) 301 39.5 0.0093 >>NP_055028 (OMIM: 142982) homeobox protein Hox-D9 [Homo (352 aa) initn: 2363 init1: 2363 opt: 2363 Z-score: 1141.6 bits: 219.7 E(85289): 7.5e-57 Smith-Waterman score: 2363; 100.0% identity (100.0% similar) in 342 aa overlap (1-342:11-352) 10 20 30 40 50 pF1KB8 MSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATA :::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 MLGGSAGRLKMSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATA 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB8 AEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 AEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWM 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB8 EPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB8 STSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 STSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSS 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB8 EPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLEL 250 260 270 280 290 300 300 310 320 330 340 pF1KB8 EKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_055 EKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD 310 320 330 340 350 >>NP_008828 (OMIM: 142971) homeobox protein Hox-C9 [Homo (260 aa) initn: 827 init1: 515 opt: 531 Z-score: 278.9 bits: 59.6 E(85289): 8.5e-09 Smith-Waterman score: 823; 46.9% identity (62.1% similar) in 343 aa overlap (1-340:1-257) 10 20 30 40 50 pF1KB8 MSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQ---GRPAGVADGPAATAAEFASCS ::..: .:::::::::.:......:.:: :. ::. .::.:.. : . .: ::: NP_008 MSATGPISNYYVDSLISHDNEDLLASRF--PATGAHPAAARPSGLV--PDCS--DFPSCS 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 FAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFP :::. ::::.::. :::: : .:::: : : :.:.. ::.:.:.::: : NP_008 FAPKPAVFSTSWAPVPSQS------SVVYHPYGPQPHLGADT----RYMRTWLEPLSG-- 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 GGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSS :: ::.::::..::. : :. NP_008 -----------------AVSFPSFPAGGRHYALKPD--AYPG------------------ 110 120 180 190 200 210 220 230 pF1KB8 SKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSD .:..:. ..: : :.. .: :: : : : : .: NP_008 -RRADCG---PGEGRSYPDYMYGS--------------PGELRDRAPQTLPSPEADA--- 130 140 150 160 240 250 260 270 280 290 pF1KB8 HPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFN . : . ::: . .:::.::.::::::::::::::::::::::::::::::: NP_008 --LAGSKHKEE--------KADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFN 170 180 190 200 210 300 310 320 330 340 pF1KB8 MYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD :::::::::::::.::::::::::::::::::::::.::: : NP_008 MYLTRDRRYEVARVLNLTERQVKIWFQNRRMKMKKMNKEKTDKEQS 220 230 240 250 260 >>NP_689952 (OMIM: 142956) homeobox protein Hox-A9 [Homo (272 aa) initn: 688 init1: 494 opt: 510 Z-score: 268.8 bits: 57.8 E(85289): 3.1e-08 Smith-Waterman score: 719; 43.1% identity (58.7% similar) in 346 aa overlap (1-337:1-268) 10 20 30 40 50 pF1KB8 MSSSGTLSNYYVDS-LIGHEG-DEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSF :...:.:.:::::: :.: .. ::. ..:. .::. :.: : . : .:. ::: NP_689 MATTGALGNYYVDSFLLGADAADELSVGRY---APGTLGQPPRQA-ATLAEHPDFSPCSF 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 APRSAVFSASWSAVPSQP----PAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLP ...::.:::. : . :::. .:::: : .:.:. :::.:::.:: : NP_689 QSKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQAPVAAAAPDGRYMRSWLEPTP 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 GFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSL : . :: :: : :::::: : : .. . .. .: NP_689 GALSFAGL------------PSSRP--------YGIKPE----PLSARRGDCPTLDTHTL 120 130 140 150 180 190 200 210 220 230 pF1KB8 SSSSKRTECS---VARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSE : .. :. : ::.: : : .: ...: .:: : NP_689 SLTD--YACGSPPVDREKQPSEG------AFSENNAENESGGDKP--------------- 160 170 180 240 250 260 270 280 290 pF1KB8 PSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELE :: :::::::::.::::::::::::::.:::::: NP_689 -------PI--------------------DPNNPAANWLHARSTRKKRCPYTKHQTLELE 190 200 210 220 300 310 320 330 340 pF1KB8 KEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD :::::::::::::::::::.:::::::::::::::::::::..:.. NP_689 KEFLFNMYLTRDRRYEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE 230 240 250 260 270 >>NP_076922 (OMIM: 142964) homeobox protein Hox-B9 [Homo (250 aa) initn: 674 init1: 467 opt: 475 Z-score: 252.7 bits: 54.7 E(85289): 2.5e-07 Smith-Waterman score: 687; 41.8% identity (58.5% similar) in 337 aa overlap (1-337:1-247) 10 20 30 40 50 60 pF1KB8 MSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAP :: :::::.:::::.:.::.... :.: : : :..: : :. :: :::: : NP_076 MSISGTLSSYYVDSIISHESEDAPPAKF-PSGQYASSRQPGHAEH-----LEFPSCSFQP 10 20 30 40 50 70 80 90 100 110 120 pF1KB8 RSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPLPGFPGGA .. ::.:::. : .: :.... ..::::. : . . : ::.:.:.:: : NP_076 KAPVFGASWA--PLSPHASGSLPSVYHPYIQPQGVPPAES---RYLRTWLEPAPR----- 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 GGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKR : ..::.: . . : : ::. .: : NP_076 ------GEAAPGQGQAAVKAEPLLG-----------APGELLKQGTPEYS---------- 110 120 130 190 200 210 220 230 240 pF1KB8 TECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPI : :..:: :. .. :: : :. : NP_076 LETSAGRE--------------------AVLSNQRPGYG-----------------DNKI 140 150 160 250 260 270 280 290 300 pF1KB8 PGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYL : .:.... :.: .::.:::.::::.::::::::::::::::::::::::: NP_076 --CEGSEDKER---PDQ-----TNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYL 170 180 190 200 210 310 320 330 340 pF1KB8 TRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD :::::.::::.:::.::::::::::::::::::.::. NP_076 TRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE 220 230 240 250 >>NP_002139 (OMIM: 142984,192950) homeobox protein Hox-D (340 aa) initn: 468 init1: 385 opt: 439 Z-score: 234.2 bits: 51.7 E(85289): 2.6e-06 Smith-Waterman score: 443; 30.9% identity (57.2% similar) in 353 aa overlap (2-336:5-327) 10 20 30 40 50 pF1KB8 MSSSGTLSNYYVDSLIGHEGDEVF----AARFGPPGPGAQGRPAGVADGPAATAAEF .:: . ... :::::. .. : :. . :: :.:. :. NP_002 MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPP-PSADMGTYGMQ---------- 10 20 30 40 60 70 80 90 100 pF1KB8 ASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVR-----S .:.. : : . : : :. :::.: . : ..:.: : . NP_002 -TCGLLP-----SLAKREVNHQ-----NMGMNVHPYIPQ---VDSWTDPNRSCRIEQPVT 50 60 70 80 90 110 120 130 140 150 160 pF1KB8 WMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIK-P-ETRAAPAPA--TAA . : .: . .. . :. . :. : . : :. .:.:. . NP_002 QQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLS 100 110 120 130 140 150 170 180 190 200 210 pF1KB8 STTSSSSTSLSSSSKRTECSVARE--SQGSSGPEFSCNSF-LQEKAAAATGGTGPG--AG .: ....:. ..: . .: . .:.. :..: .. ...: ..: : . NP_002 QTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQ 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB8 IGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKR . . . :: : .: . :.. : :... ..... ..:..::. :.: :::: NP_002 VESPEAKGGLPEERSC----LAEVSVSSPEVQEKE-SKEEIKSDTPTSNWLTAKSGRKKR 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB8 CPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCP :::::.:::::::::::::::::.:: :... .:::.:::::::::::::.::::.: NP_002 CPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRI 280 290 300 310 320 330 340 pF1KB8 KGD NP_002 RELTANLTFS 340 >>NP_061824 (OMIM: 142957) homeobox protein Hox-A10 [Hom (410 aa) initn: 607 init1: 389 opt: 422 Z-score: 225.3 bits: 50.4 E(85289): 8.2e-06 Smith-Waterman score: 514; 37.5% identity (56.2% similar) in 315 aa overlap (29-336:132-397) 10 20 30 40 50 pF1KB8 MSSSGTLSNYYVDSLIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSF ::: : : : : : . .:::: NP_061 GLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPP--PPQPPQPAPQATSCSF 110 120 130 140 150 60 70 80 90 100 110 pF1KB8 APR-----SAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWMEPL : : . : . :. .:: .. . : ::: : .. : : .... : NP_061 AQNIKEESSYCLYDSADKCPKVSATAAELAPF--PRGPPPDGCALGTSSGVPVPGYFR-L 160 170 180 190 200 210 120 130 140 150 160 170 pF1KB8 PGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTS : : : :.::::. : .: :. : :: . . : :: : : NP_061 SQAYGTAKGYGSGGGGAQQLGAGPFPAQPP-GRGFDL-P-------PALA---------S 220 230 240 250 180 190 200 210 220 230 pF1KB8 LSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPS :... : : : .. : ..: :.: :.. : . ..:: NP_061 GSADAARKE----RALDSPPPPTLAC-------------GSG-GGSQGDEEAHASSSAAE 260 270 280 290 300 240 250 260 270 280 290 pF1KB8 ACSDHPIPGCSLKEEEKQHSQPQQQQL--DPNNPAANWIHARSTRKKRCPYTKYQTLELE : : :. :.....:....: . .. ::::. :.: :::::::::.:::::: NP_061 ELS--PAPS------ESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELE 310 320 330 340 350 300 310 320 330 340 pF1KB8 KEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD :::::::::::.:: :..: ..::.:::::::::::::.:::..: NP_061 KEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRIRELTANFNFS 360 370 380 390 400 410 >>NP_059105 (OMIM: 605560) homeobox protein Hox-C10 [Hom (342 aa) initn: 437 init1: 384 opt: 404 Z-score: 217.7 bits: 48.7 E(85289): 2.2e-05 Smith-Waterman score: 422; 38.5% identity (61.5% similar) in 213 aa overlap (140-336:122-329) 110 120 130 140 150 160 pF1KB8 MEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPET----RAAPAPATAAS ::: . . ::. . .:.: NP_059 VGRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESCLGEHEVPVP----- 100 110 120 130 140 170 180 190 200 210 220 pF1KB8 TTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGT-----GPGAGI . .: : :. .: .:: : . .. . : : .. . :: : . NP_059 SYYRASPSYSALDKTPHCSGANDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDS 150 160 170 180 190 200 230 240 250 260 270 pF1KB8 GAATGTGGSSEPSACSDHPIPGCSLKEEEKQ-HSQPQ------QQQLDPNNPAANWIHAR . . . ..: : . . :. : ::. : :.:. .... .: ..::. :. NP_059 QTPSPNEIKTEQSLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWLTAK 210 220 230 240 250 260 280 290 300 310 320 330 pF1KB8 STRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKM : :::::::::.:::::::::::::::::.:: :... .:::.:::::::::::::.::: NP_059 SGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKM 270 280 290 300 310 320 340 pF1KB8 SKEKCPKGD ..: NP_059 NRENRIRELTSNFNFT 330 340 >>NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [Homo (270 aa) initn: 332 init1: 264 opt: 364 Z-score: 200.0 bits: 45.1 E(85289): 0.00021 Smith-Waterman score: 364; 36.4% identity (60.0% similar) in 225 aa overlap (124-337:43-257) 100 110 120 130 140 150 pF1KB8 PLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYGIKPE : : : : : : :: . :.: . NP_061 YPNGPDYQLHNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSG---HFGSGER 20 30 40 50 60 160 170 180 190 200 pF1KB8 TRAAPAPATAASTTSS-SSTSLSSSSKRTE---CSVARESQGSSGPEFSCNSFLQEKAAA .:. : :.:: . :. . :. : . . ::.. : ::.. . . ::. . ..:. NP_061 ARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSSGAS 70 80 90 100 110 120 210 220 230 240 250 260 pF1KB8 ATGGT---GPGAGIGAATGT----GGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDP : .:. . :.:.:.:. .::: .. ...: :. . . : ...: NP_061 ADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPA----PPAQPQIYPWMRKLHI 130 140 150 160 170 180 270 280 290 300 310 320 pF1KB8 NNPAANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIW .. : . .. : ::.:::::::::: :: :::: :: :.:. : :.:::.::: NP_061 SHDN---IGGPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIW 190 200 210 220 230 240 330 340 pF1KB8 FQNRRMKMKKMSKEKCPKGD ::::::: :: .: : NP_061 FQNRRMKWKKDNKLKSMSMAAAGGAFRP 250 260 270 >>NP_005514 (OMIM: 142958,605432) homeobox protein Hox-A (313 aa) initn: 441 init1: 305 opt: 349 Z-score: 192.2 bits: 43.8 E(85289): 0.00058 Smith-Waterman score: 360; 28.8% identity (57.1% similar) in 312 aa overlap (45-337:7-303) 20 30 40 50 60 70 pF1KB8 LIGHEGDEVFAARFGPPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPS :: .. . ::.. . ::. : .: NP_005 MDFDERGPCSSNMYLPSCTYYVSGPDFSSLPSFLP- 10 20 30 80 90 100 110 120 130 pF1KB8 QPPAAAAMSGLYHPYVPPPPLAASASEPGRYV--RSW-MEPLPGF-PGGAGGGGGGGGGG : :.. :. : .: .: : : : . .:: . : : . .. NP_005 QTPSSRPMTYSYSSNLP-------QVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEEL 40 50 60 70 80 140 150 160 170 pF1KB8 PGRGPSPGPSGPANGRHYGIKPETRAA----PAPATAASTTSSSSTS----------LSS : .:: : : . .. : :.::.... :. . . . . NP_005 VHRDCLQAPS--AAGVPGDVLAKSSANVYHHPTPAVSSNFYSTVGRNGVLPQAFDQFFET 90 100 110 120 130 140 180 190 200 210 220 230 pF1KB8 SSKRTECSVARESQGSSGPEFSCNSFLQEKAAAATGGTG-PGAGIGAATGTGGSSEPSAC . : .. . :... : . . .::::...:: :... . . : :: : .: NP_005 AYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAA 150 160 170 180 190 200 240 250 260 270 280 290 pF1KB8 SDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTKYQTLELEKEFL ... ... .. :.:.... .. :.. : :::::::::::: :::.::. NP_005 AEEK----ERRRRPESSSSPESSSGHTEDKAGGSSGQR-TRKKRCPYTKYQIRELEREFF 210 220 230 240 250 260 300 310 320 330 340 pF1KB8 FNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD :..:.....: ...:.::::.::::::::::::: ::..... NP_005 FSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKINRDRLQYYSANPLL 270 280 290 300 310 >>NP_008827 (OMIM: 142950) homeobox protein Hox-A7 [Homo (230 aa) initn: 368 init1: 274 opt: 340 Z-score: 189.4 bits: 42.9 E(85289): 0.00082 Smith-Waterman score: 340; 36.8% identity (61.6% similar) in 185 aa overlap (159-339:16-194) 130 140 150 160 170 180 pF1KB8 GGPGRGPSPGPSGPANGRHYGIKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARE : :. ... .: :.. .:.:. ... NP_008 MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGAGAG 10 20 30 40 190 200 210 220 230 240 pF1KB8 SQGSSGPE-FSCNSFLQEKAAAATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKE . .:. : .. :: : .. :. : : : . .. .. :. ::: .:. . NP_008 AFASTVPGLYNVNSPLYQSPFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKTD 50 60 70 80 90 100 250 260 270 280 290 300 pF1KB8 EEKQHSQPQQQ-QLDPNNPAANWIHARSTRKKRC--PYTKYQTLELEKEFLFNMYLTRDR : :. . . .. : :... . .:: ::.:::::::::: :: :::: : NP_008 EGALHGAAEANFRIYP------WMRSSGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRR 110 120 130 140 150 310 320 330 340 pF1KB8 RYEVARILNLTERQVKIWFQNRRMKMKKMSKEKCPKGD : :.:. : :::::.:::::::::: :: :.. : NP_008 RIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEGPTAAAAPEGAVPSAAATAAADKADEE 160 170 180 190 200 210 NP_008 DDDEEEEDEEE 220 230 342 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:49:06 2016 done: Sat Nov 5 00:49:08 2016 Total Scan time: 9.200 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]