Result of FASTA (omim) for pF1KB8963
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8963, 350 aa
  1>>>pF1KB8963 350 - 350 aa - 350 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.5207+/-0.000472; mu= 20.9235+/- 0.029
 mean_var=109.8579+/-26.458, 0's: 0 Z-trim(110.0): 708  B-trim: 864 in 1/48
 Lambda= 0.122365
 statistics sampled from 17505 (18319) to 17505 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.566), E-opt: 0.2 (0.215), width:  16
 Scan time:  7.480

The best scores are:                                      opt bits E(85289)
NP_005949 (OMIM: 600665) melatonin receptor type 1 ( 350) 2315 420.3 3.2e-117
XP_011530304 (OMIM: 600665) PREDICTED: melatonin r ( 265) 1777 325.1 1.1e-88
NP_005950 (OMIM: 125853,600804) melatonin receptor ( 362) 1392 257.3 3.7e-68
XP_011541141 (OMIM: 125853,600804) PREDICTED: mela ( 362) 1392 257.3 3.7e-68
XP_016873266 (OMIM: 125853,600804) PREDICTED: mela ( 320) 1212 225.5 1.3e-58
NP_004215 (OMIM: 300207) melatonin-related recepto ( 617) 1142 213.6 9.5e-55
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349)  451 91.2 3.7e-18
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389)  451 91.3 3.9e-18
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392)  451 91.3 3.9e-18
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397)  451 91.3 3.9e-18
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400)  451 91.3 3.9e-18
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403)  451 91.3   4e-18
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406)  451 91.3   4e-18
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414)  451 91.3   4e-18
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418)  451 91.3   4e-18
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420)  451 91.3 4.1e-18
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446)  451 91.4 4.2e-18
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493)  451 91.4 4.4e-18
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493)  451 91.4 4.4e-18
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370)  431 87.7 4.4e-17
NP_001043 (OMIM: 182454) somatostatin receptor typ ( 388)  417 85.3 2.5e-16
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372)  416 85.1 2.7e-16
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369)  412 84.4 4.5e-16
NP_003848 (OMIM: 603691) galanin receptor type 2 [ ( 387)  407 83.5 8.4e-16
NP_001138753 (OMIM: 600018) mu-type opioid recepto ( 319)  401 82.3 1.6e-15
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380)  399 82.1 2.2e-15
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409)  399 82.1 2.3e-15
NP_001044 (OMIM: 182455) somatostatin receptor typ ( 364)  397 81.7 2.8e-15
NP_001166031 (OMIM: 182455) somatostatin receptor  ( 364)  397 81.7 2.8e-15
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370)  394 81.2   4e-15
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370)  394 81.2   4e-15
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370)  394 81.2   4e-15
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin  ( 370)  394 81.2   4e-15
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin  ( 388)  394 81.2 4.1e-15
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin  ( 388)  394 81.2 4.1e-15
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin  ( 388)  394 81.2 4.1e-15
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399)  394 81.2 4.2e-15
NP_001272456 (OMIM: 600018) mu-type opioid recepto ( 292)  391 80.5 5.1e-15
NP_001138752 (OMIM: 600018) mu-type opioid recepto ( 300)  391 80.5 5.2e-15
NP_001138759 (OMIM: 600018) mu-type opioid recepto ( 300)  391 80.5 5.2e-15
XP_016866395 (OMIM: 600018) PREDICTED: mu-type opi ( 300)  391 80.5 5.2e-15
NP_001272455 (OMIM: 600018) mu-type opioid recepto ( 300)  391 80.5 5.2e-15
NP_001272457 (OMIM: 600018) mu-type opioid recepto ( 314)  391 80.5 5.3e-15
XP_016866394 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  391 80.6 5.6e-15
XP_011534158 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  391 80.6 5.6e-15
XP_011534164 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  391 80.6 5.6e-15
XP_011534155 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  391 80.6 5.6e-15
XP_016866393 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  391 80.6 5.6e-15
XP_016866392 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  391 80.6 5.6e-15
XP_011534153 (OMIM: 600018) PREDICTED: mu-type opi ( 346)  391 80.6 5.6e-15


>>NP_005949 (OMIM: 600665) melatonin receptor type 1A [H  (350 aa)
 initn: 2315 init1: 2315 opt: 2315  Z-score: 2225.5  bits: 420.3 E(85289): 3.2e-117
Smith-Waterman score: 2315; 99.7% identity (99.7% similar) in 350 aa overlap (1-350:1-350)

               10        20        30        40        50        60
pF1KB8 MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETLQYDPRIYSCTFA
       ::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_005 IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
              250       260       270       280       290       300

              310       320       330       340       350
pF1KB8 NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
              310       320       330       340       350

>>XP_011530304 (OMIM: 600665) PREDICTED: melatonin recep  (265 aa)
 initn: 1777 init1: 1777 opt: 1777  Z-score: 1713.4  bits: 325.1 E(85289): 1.1e-88
Smith-Waterman score: 1777; 99.6% identity (99.6% similar) in 265 aa overlap (86-350:1-265)

          60        70        80        90       100       110     
pF1KB8 KKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSI
                                     ::::::::::::::::::::::::::::::
XP_011                               MSIFNNGWNLGYLHCQVSGFLMGLSVIGSI
                                             10        20        30

         120       130       140       150       160       170     
pF1KB8 FNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETLQYDPRIY
       :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_011 FNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIY
               40        50        60        70        80        90

         180       190       200       210       220       230     
pF1KB8 SCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFR
              100       110       120       130       140       150

         240       250       260       270       280       290     
pF1KB8 NFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIY
              160       170       180       190       200       210

         300       310       320       330       340       350
pF1KB8 GLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
              220       230       240       250       260     

>>NP_005950 (OMIM: 125853,600804) melatonin receptor typ  (362 aa)
 initn: 1396 init1: 1373 opt: 1392  Z-score: 1344.7  bits: 257.3 E(85289): 3.7e-68
Smith-Waterman score: 1392; 61.2% identity (83.0% similar) in 335 aa overlap (3-337:24-350)

                                    10        20        30         
pF1KB8                      MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIV
                              : ::: :. . :       :: :.: ::. ::: : .
NP_005 MSENGSFANCCEAGGWAVRPGWSGAGSARPSRT-P-------RPPWVAPALSAVLIVTTA
               10        20        30                40        50  

      40        50        60        70        80        90         
pF1KB8 VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLH
       ::..::::::::: ::.:::::::.:.::::.::::::.:::::.:..:: .:: ::  :
NP_005 VDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEH
             60        70        80        90       100       110  

     100       110       120       130       140       150         
pF1KB8 CQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAV
       :..:.:.::::::::.::::.::::::::::::. : ..:   ..  .. ::::::..:.
NP_005 CKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVAL
            120       130       140       150       160       170  

     160       170       180       190       200       210         
pF1KB8 LPNLRAETLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQ
       :::. . .:.:::::::::: :..:. :: ::::.:::.:. .: :::::::.::::.:.
NP_005 LPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARR
            180       190       200       210       220       230  

     220       230       240       250       260       270         
pF1KB8 RVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVA
       ..::. .  :::.:.:.:.:::::::.::::::::: :::::: .:  :.:.::: :::.
NP_005 KAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVT
            240       250       260       270       280       290  

     280       290       300       310       320       330         
pF1KB8 SYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLM
       :: .::::::::::.:::::::::.::.::...: . :  . :.:.    .   .:.:  
NP_005 SYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPI
            300       310       320       330       340       350  

     340       350
pF1KB8 TNNNVVKVDSV
                  
NP_005 IGVQHQADAL 
            360   

>>XP_011541141 (OMIM: 125853,600804) PREDICTED: melatoni  (362 aa)
 initn: 1396 init1: 1373 opt: 1392  Z-score: 1344.7  bits: 257.3 E(85289): 3.7e-68
Smith-Waterman score: 1392; 61.2% identity (83.0% similar) in 335 aa overlap (3-337:24-350)

                                    10        20        30         
pF1KB8                      MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIV
                              : ::: :. . :       :: :.: ::. ::: : .
XP_011 MSENGSFANCCEAGGWAVRPGWSGAGSARPSRT-P-------RPPWVAPALSAVLIVTTA
               10        20        30                40        50  

      40        50        60        70        80        90         
pF1KB8 VDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLH
       ::..::::::::: ::.:::::::.:.::::.::::::.:::::.:..:: .:: ::  :
XP_011 VDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEH
             60        70        80        90       100       110  

     100       110       120       130       140       150         
pF1KB8 CQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAV
       :..:.:.::::::::.::::.::::::::::::. : ..:   ..  .. ::::::..:.
XP_011 CKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVAL
            120       130       140       150       160       170  

     160       170       180       190       200       210         
pF1KB8 LPNLRAETLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQ
       :::. . .:.:::::::::: :..:. :: ::::.:::.:. .: :::::::.::::.:.
XP_011 LPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARR
            180       190       200       210       220       230  

     220       230       240       250       260       270         
pF1KB8 RVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVA
       ..::. .  :::.:.:.:.:::::::.::::::::: :::::: .:  :.:.::: :::.
XP_011 KAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVT
            240       250       260       270       280       290  

     280       290       300       310       320       330         
pF1KB8 SYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLM
       :: .::::::::::.:::::::::.::.::...: . :  . :.:.    .   .:.:  
XP_011 SYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPI
            300       310       320       330       340       350  

     340       350
pF1KB8 TNNNVVKVDSV
                  
XP_011 IGVQHQADAL 
            360   

>>XP_016873266 (OMIM: 125853,600804) PREDICTED: melatoni  (320 aa)
 initn: 1218 init1: 1195 opt: 1212  Z-score: 1173.5  bits: 225.5 E(85289): 1.3e-58
Smith-Waterman score: 1212; 56.4% identity (81.4% similar) in 312 aa overlap (26-337:1-308)

               10        20        30        40        50        60
pF1KB8 MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
                                .:... :    .. ... :     .:  ..  : .
XP_016                          MATVFFCFPNSSMGISMAGA----MSFIHHCVLLE
                                        10        20            30 

               70        80        90       100       110       120
pF1KB8 AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
        ::.:.::::.::::::.:::::.:..:: .:: ::  ::..:.:.::::::::.::::.
XP_016 CGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITA
              40        50        60        70        80        90 

              130       140       150       160       170       180
pF1KB8 IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETLQYDPRIYSCTFA
       ::::::::::::. : ..:   ..  .. ::::::..:.:::. . .:.:::::::::: 
XP_016 IAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFI
             100       110       120       130       140       150 

              190       200       210       220       230       240
pF1KB8 QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
       :..:. :: ::::.:::.:. .: :::::::.::::.:...::. .  :::.:.:.:.::
XP_016 QTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTM
             160       170       180       190       200       210 

              250       260       270       280       290       300
pF1KB8 FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
       :::::.::::::::: :::::: .:  :.:.::: :::.:: .::::::::::.::::::
XP_016 FVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQ
             220       230       240       250       260       270 

              310       320       330       340       350
pF1KB8 NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
       :::.::.::...: . :  . :.:.    .   .:.:             
XP_016 NFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL 
             280       290       300       310       320 

>>NP_004215 (OMIM: 300207) melatonin-related receptor [H  (617 aa)
 initn: 1134 init1: 780 opt: 1142  Z-score: 1103.9  bits: 213.6 E(85289): 9.5e-55
Smith-Waterman score: 1142; 51.1% identity (79.3% similar) in 305 aa overlap (23-327:24-326)

                10        20        30        40        50         
pF1KB8  MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLR
                              :  :   . :....:::::..:: .:::.: .:::::
NP_004 MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLR
               10        20        30        40        50        60

      60        70        80        90       100       110         
pF1KB8 NAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNIT
       :.::::::::.:::..::::::::.: ..  .::.:. :.::. ::. ::::.::::::.
NP_004 NSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIV
               70        80        90       100       110       120

     120       130       140       150       160       170         
pF1KB8 GIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETLQYDPRIYSCTF
       .:::::::::::::.:....: .:.  :... :..:. :::::.   :..:::: :.: :
NP_004 AIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIF
              130       140       150       160       170       180

     180       190       200       210       220       230         
pF1KB8 AQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVT
           . ..:...: .::..:..:: :::.:::  :: .:.     ..:  .  . :::.:
NP_004 NYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARD--PAGQNPDNQLAEVRNFLT
              190       200       210       220         230        

     240       250       260       270       280       290         
pF1KB8 MFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLN
       :::.:.:::.:: :.: . . :: .:  :. .::.::..:.:..:::::::::.::::::
NP_004 MFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLN
      240       250       260       270       280       290        

     300       310       320       330       340       350         
pF1KB8 QNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV         
       .:::.::  :. ..    .::    .:.                                
NP_004 ENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAV
      300       310       320       330       340       350        

>>NP_001471 (OMIM: 600377) galanin receptor type 1 [Homo  (349 aa)
 initn: 285 init1: 210 opt: 451  Z-score: 447.1  bits: 91.2 E(85289): 3.7e-18
Smith-Waterman score: 451; 28.8% identity (61.1% similar) in 347 aa overlap (2-336:10-343)

                        10         20        30        40        50
pF1KB8         MQGNGS-ALPNASQP-VLRGDGARPSWLASALACVLIFTIVVDILGNLLVIL
                .::.:   : : .:  : : :..   ... ..  :::..   .::: ::: 
NP_001 MELAVGNLSEGNASWPEPPAPEPGPLFGIGVEN--FVTLVVFGLIFAL--GVLGNSLVIT
               10        20        30          40          50      

                 60        70        80        90       100        
pF1KB8 SVYRNK--KLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMG
        . :.:  : :.. :.:...:..:::.  ..  :.         : :: . :.   ... 
NP_001 VLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFT
         60        70        80        90       100       110      

      110       120       130       140       150       160        
pF1KB8 LSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETL
       .:.. :::........::  : :: . ..:  :.:.:  :  :: :..: . :    . :
NP_001 VSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGL
        120       130       140       150       160       170      

      170       180             190       200       210       220  
pF1KB8 QYDPRIYSCTFAQSV------SSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVK
        . ::  . ::          ..::.. . :: .:.:.... ::: ..   . ......:
NP_001 -FHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKV---LNHLHKKLK
         180       190       200       210       220          230  

            230       240       250       260       270        280 
pF1KB8 PDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLF-VASY
        . . : . .  ..  :..:: :.:.: : : ..: : .      ..:    .:: ....
NP_001 -NMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTP--ASFLFRITAH
             240       250       260       270         280         

             290       300       310        320       330       340
pF1KB8 YMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARV-FFVDSSNDVADRVKWKPSPLMT
        .:: :: .: :::..:..:::: :....   :  :    ......  .:.   ::    
NP_001 CLAYSNSSVNPIIYAFLSENFRKAYKQVF--KCHIRKDSHLSDTKESKSRIDTPPSTNCT
     290       300       310         320       330       340       

              350
pF1KB8 NNNVVKVDSV
                 
NP_001 HV        
                 

>>NP_001138757 (OMIM: 600018) mu-type opioid receptor is  (389 aa)
 initn: 331 init1: 117 opt: 451  Z-score: 446.6  bits: 91.3 E(85289): 3.9e-18
Smith-Waterman score: 451; 25.8% identity (59.6% similar) in 329 aa overlap (23-341:65-380)

                       10        20        30          40        50
pF1KB8         MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIV--VDILGNLLVIL
                                     :: . .:.. . ...::  : ..::.::. 
NP_001 SHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPS-MITAITIMALYSIVCVVGLFGNFLVMY
           40        50        60         70        80        90   

               60        70        80        90       100       110
pF1KB8 SVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLS
        . :  :...: ::.. .::.:: ..:    :.  .. . . : .: . :..   .   .
NP_001 VIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYN
           100       110        120       130       140       150  

              120       130       140       150       160       170
pF1KB8 VIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETLQY
       .. :::..  ....::  .:: .:   . . .:.    .  :.:. :  :: .   : .:
NP_001 MFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKY
            160       170       180       190       200       210  

              180            190       200       210       220     
pF1KB8 DPRIYSCTFAQSVSSAY-----TIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDR
            .::.. :  . :      : : .: :..:..:.  ::    ...:.... :.   
NP_001 RQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCY---GLMILRLKS-VRMLS
            220       230       240       250          260         

         230       240        250         260       270       280  
pF1KB8 KPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF--IGLAVASDPASMVPRIPEWLFVASYY
         : : ...: .. : .:: ..: .::.:...  :  :... : .    .  : :  .  
NP_001 GSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVS-WHFCIA--
      270       280       290       300       310        320       

            290       300       310       320       330       340  
pF1KB8 MAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNN
       ..: ::::: ..:..:..::.. .:.    .:      ....:..  : . .  :  .: 
NP_001 LGYTNSCLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQQNSTRIRQNTRDHPSTANT
         330       340       350           360       370       380 

            350
pF1KB8 NVVKVDSV
               
NP_001 VDRTNHQS
               

>>NP_001008504 (OMIM: 600018) mu-type opioid receptor is  (392 aa)
 initn: 331 init1: 117 opt: 451  Z-score: 446.6  bits: 91.3 E(85289): 3.9e-18
Smith-Waterman score: 451; 25.8% identity (59.6% similar) in 329 aa overlap (23-341:65-380)

                       10        20        30          40        50
pF1KB8         MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIV--VDILGNLLVIL
                                     :: . .:.. . ...::  : ..::.::. 
NP_001 SHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPS-MITAITIMALYSIVCVVGLFGNFLVMY
           40        50        60         70        80        90   

               60        70        80        90       100       110
pF1KB8 SVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLS
        . :  :...: ::.. .::.:: ..:    :.  .. . . : .: . :..   .   .
NP_001 VIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYN
           100       110        120       130       140       150  

              120       130       140       150       160       170
pF1KB8 VIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETLQY
       .. :::..  ....::  .:: .:   . . .:.    .  :.:. :  :: .   : .:
NP_001 MFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKY
            160       170       180       190       200       210  

              180            190       200       210       220     
pF1KB8 DPRIYSCTFAQSVSSAY-----TIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDR
            .::.. :  . :      : : .: :..:..:.  ::    ...:.... :.   
NP_001 RQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCY---GLMILRLKS-VRMLS
            220       230       240       250          260         

         230       240        250         260       270       280  
pF1KB8 KPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF--IGLAVASDPASMVPRIPEWLFVASYY
         : : ...: .. : .:: ..: .::.:...  :  :... : .    .  : :  .  
NP_001 GSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVS-WHFCIA--
      270       280       290       300       310        320       

            290       300       310       320       330       340  
pF1KB8 MAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNN
       ..: ::::: ..:..:..::.. .:.    .:      ....:..  : . .  :  .: 
NP_001 LGYTNSCLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQQNSTRIRQNTRDHPSTANT
         330       340       350           360       370       380 

            350   
pF1KB8 NVVKVDSV   
                  
NP_001 VDRTNHQVRSL
             390  

>>NP_001138755 (OMIM: 600018) mu-type opioid receptor is  (397 aa)
 initn: 331 init1: 117 opt: 451  Z-score: 446.5  bits: 91.3 E(85289): 3.9e-18
Smith-Waterman score: 451; 25.8% identity (59.6% similar) in 329 aa overlap (23-341:65-380)

                       10        20        30          40        50
pF1KB8         MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIV--VDILGNLLVIL
                                     :: . .:.. . ...::  : ..::.::. 
NP_001 SHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPS-MITAITIMALYSIVCVVGLFGNFLVMY
           40        50        60         70        80        90   

               60        70        80        90       100       110
pF1KB8 SVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLS
        . :  :...: ::.. .::.:: ..:    :.  .. . . : .: . :..   .   .
NP_001 VIVRYTKMKTATNIYIFNLALAD-ALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYN
           100       110        120       130       140       150  

              120       130       140       150       160       170
pF1KB8 VIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAETLQY
       .. :::..  ....::  .:: .:   . . .:.    .  :.:. :  :: .   : .:
NP_001 MFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKY
            160       170       180       190       200       210  

              180            190       200       210       220     
pF1KB8 DPRIYSCTFAQSVSSAY-----TIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDR
            .::.. :  . :      : : .: :..:..:.  ::    ...:.... :.   
NP_001 RQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCY---GLMILRLKS-VRMLS
            220       230       240       250          260         

         230       240        250         260       270       280  
pF1KB8 KPKLKPQDFRNFVTM-FVVFVLFAICWAPLNF--IGLAVASDPASMVPRIPEWLFVASYY
         : : ...: .. : .:: ..: .::.:...  :  :... : .    .  : :  .  
NP_001 GSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVS-WHFCIA--
      270       280       290       300       310        320       

            290       300       310       320       330       340  
pF1KB8 MAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNN
       ..: ::::: ..:..:..::.. .:.    .:      ....:..  : . .  :  .: 
NP_001 LGYTNSCLNPVLYAFLDENFKRCFRE----FCIPTSSNIEQQNSTRIRQNTRDHPSTANT
         330       340       350           360       370       380 

            350        
pF1KB8 NVVKVDSV        
                       
NP_001 VDRTNHQRERRQKSDW
             390       




350 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 01:38:25 2016 done: Sat Nov  5 01:38:27 2016
 Total Scan time:  7.480 Total Display time:  0.060

Function used was FASTA [36.3.4 Apr, 2011]
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