FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8976, 372 aa 1>>>pF1KB8976 372 - 372 aa - 372 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6113+/-0.000443; mu= 20.4766+/- 0.027 mean_var=117.6466+/-29.565, 0's: 0 Z-trim(110.8): 621 B-trim: 910 in 1/52 Lambda= 0.118245 statistics sampled from 18448 (19208) to 18448 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.584), E-opt: 0.2 (0.225), width: 16 Scan time: 7.530 The best scores are: opt bits E(85289) NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 2496 437.7 2e-122 NP_116743 (OMIM: 601613) C-X-C chemokine receptor ( 327) 2184 384.4 2e-106 NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 845 156.1 1.2e-37 XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 845 156.1 1.2e-37 NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 845 156.1 1.3e-37 XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 845 156.1 1.3e-37 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 804 149.0 1.5e-35 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 804 149.0 1.5e-35 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 804 149.0 1.5e-35 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 804 149.0 1.5e-35 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 804 149.0 1.5e-35 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 804 149.0 1.5e-35 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 788 146.3 1e-34 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 788 146.3 1e-34 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 788 146.3 1e-34 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 788 146.3 1.1e-34 NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 754 140.5 5.6e-33 NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 741 138.2 2.5e-32 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 712 133.3 8.1e-31 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 712 133.3 8.2e-31 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 687 129.1 1.6e-29 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 687 129.1 1.6e-29 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 687 129.1 1.6e-29 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 687 129.1 1.6e-29 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 666 125.5 1.9e-28 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 666 125.5 1.9e-28 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 655 123.6 6.9e-28 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 655 123.6 6.9e-28 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 644 121.7 2.5e-27 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 628 119.0 1.7e-26 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 628 119.0 1.7e-26 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 624 118.3 2.7e-26 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 624 118.3 2.7e-26 NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 623 118.2 3.1e-26 NP_057686 (OMIM: 600240) C-C chemokine receptor ty ( 362) 621 117.8 3.9e-26 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 619 117.5 5.1e-26 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 613 116.5 9.9e-26 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 607 115.4 2e-25 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 607 115.4 2e-25 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 607 115.4 2e-25 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 607 115.4 2e-25 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 607 115.5 2.1e-25 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 607 115.5 2.1e-25 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 607 115.5 2.2e-25 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 607 115.5 2.2e-25 NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 555 106.6 9.5e-23 NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 555 106.6 9.5e-23 NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 555 106.6 9.9e-23 NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 555 106.6 1e-22 NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 555 106.6 1e-22 >>NP_001707 (OMIM: 601613) C-X-C chemokine receptor type (372 aa) initn: 2496 init1: 2496 opt: 2496 Z-score: 2318.8 bits: 437.7 E(85289): 2e-122 Smith-Waterman score: 2496; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372) 10 20 30 40 50 60 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 IFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 VVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 PVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSL 310 320 330 340 350 360 370 pF1KB8 SESENATSLTTF :::::::::::: NP_001 SESENATSLTTF 370 >>NP_116743 (OMIM: 601613) C-X-C chemokine receptor type (327 aa) initn: 2184 init1: 2184 opt: 2184 Z-score: 2031.7 bits: 384.4 E(85289): 2e-106 Smith-Waterman score: 2184; 100.0% identity (100.0% similar) in 327 aa overlap (46-372:1-327) 20 30 40 50 60 70 pF1KB8 DLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSLIFLLGVIGNVLVLVI :::::::::::::::::::::::::::::: NP_116 MASFKAVFVPVAYSLIFLLGVIGNVLVLVI 10 20 30 80 90 100 110 120 130 pF1KB8 LERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 LERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYC 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 SSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 SSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHH 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB8 NNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 NNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQ 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 KAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 KAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHC 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 CLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSLSESENATSLTTF ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_116 CLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSLSESENATSLTTF 280 290 300 310 320 >>NP_001495 (OMIM: 300574) C-X-C chemokine receptor type (368 aa) initn: 788 init1: 444 opt: 845 Z-score: 796.7 bits: 156.1 E(85289): 1.2e-37 Smith-Waterman score: 845; 40.9% identity (68.3% similar) in 357 aa overlap (14-367:20-364) 10 20 30 40 50 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFV ::.. : .: .: : . :: . .: .:. NP_001 MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESD-SCCTSPPCPQ---DFSLNFDRAFL 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 PVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVG :. :::.::::..:: : ..: .: . :::.:::.:::::: :::. ::. .....: NP_001 PALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 WVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIW ::.:. :::.. :: ..::: ..::::::. :::: ::::.. ::. . .:: ..: NP_001 WVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVW 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LVGFLLALPEILFAKVSQGHHNNSL--PRCTFSQENQAETHAWFTSRFLYHVAGFLLPML . .:.:::...: .. ::.. : .: .. . ..: . : : :::::::.: NP_001 GLCLLFALPDFIFLSA---HHDERLNATHCQYNFPQVGRT----ALRVLQLVAGFLLPLL 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 VMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDN ::..::. .. : ..: .: .:.:....:. : :::.:::.:...: : : :. NP_001 VMAYCYAHILAVL-LVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALAR 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 TCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLF .: .. . :: .. :: ::::::.::.:.::::: . :: .::: . .: . NP_001 NCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQP 290 300 310 320 330 340 360 370 pF1KB8 PSWRR-SSLSESENATSLTTF : :: :: ::. .:. NP_001 SSSRRDSSWSETSEASYSGL 350 360 >>XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemokine (378 aa) initn: 788 init1: 444 opt: 845 Z-score: 796.6 bits: 156.1 E(85289): 1.2e-37 Smith-Waterman score: 845; 40.9% identity (68.3% similar) in 357 aa overlap (14-367:30-374) 10 20 30 40 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGP ::.. : .: .: : . :: XP_005 MPGLAHSPGSPQGWVSDHQVLNDAEVAALLENFSSSYDYGENESD-SCCTSPPCPQ---D 10 20 30 40 50 50 60 70 80 90 100 pF1KB8 LMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFIL . .: .:.:. :::.::::..:: : ..: .: . :::.:::.:::::: :::. : XP_005 FSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTL 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB8 PFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLL :. .....: ::.:. :::.. :: ..::: ..::::::. :::: ::::.. ::. XP_005 PLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPA 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB8 SIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSL--PRCTFSQENQAETHAWFTSRFLY . .:: ..: . .:.:::...: .. ::.. : .: .. . ..: . : : XP_005 RVTLTCLAVWGLCLLFALPDFIFLSA---HHDERLNATHCQYNFPQVGRT----ALRVLQ 180 190 200 210 220 230 240 250 260 270 280 pF1KB8 HVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLD :::::::.:::..::. .. : ..: .: .:.:....:. : :::.:::.:...: XP_005 LVAGFLLPLLVMAYCYAHILAVL-LVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVD 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB8 TLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGC : : :. .: .. . :: .. :: ::::::.::.:.::::: . :: .::: XP_005 ILMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGC 290 300 310 320 330 340 350 360 370 pF1KB8 TGPASLCQLFPSWRR-SSLSESENATSLTTF . .: . : :: :: ::. .:. XP_005 PNQRGLQRQPSSSRRDSSWSETSEASYSGL 350 360 370 >>NP_001136269 (OMIM: 300574) C-X-C chemokine receptor t (415 aa) initn: 788 init1: 444 opt: 845 Z-score: 796.2 bits: 156.1 E(85289): 1.3e-37 Smith-Waterman score: 845; 40.9% identity (68.3% similar) in 357 aa overlap (14-367:67-411) 10 20 30 40 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEG ::.. : .: .: : . :: NP_001 PGLYTAPSSPFPPSQVSDHQVLNDAEVAALLENFSSSYDYGENESD-SCCTSPPCPQ--- 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB8 PLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFI . .: .:.:. :::.::::..:: : ..: .: . :::.:::.:::::: :::. NP_001 DFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLT 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB8 LPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRL ::. .....: ::.:. :::.. :: ..::: ..::::::. :::: ::::.. ::. NP_001 LPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPP 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB8 LSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSL--PRCTFSQENQAETHAWFTSRFL . .:: ..: . .:.:::...: .. ::.. : .: .. . ..: . : : NP_001 ARVTLTCLAVWGLCLLFALPDFIFLSA---HHDERLNATHCQYNFPQVGRT----ALRVL 220 230 240 250 260 230 240 250 260 270 280 pF1KB8 YHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFL :::::::.:::..::. .. : ..: .: .:.:....:. : :::.:::.:... NP_001 QLVAGFLLPLLVMAYCYAHILAVL-LVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLV 270 280 290 300 310 320 290 300 310 320 330 340 pF1KB8 DTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLG : : : :. .: .. . :: .. :: ::::::.::.:.::::: . :: .:: NP_001 DILMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLG 330 340 350 360 370 380 350 360 370 pF1KB8 CTGPASLCQLFPSWRR-SSLSESENATSLTTF : . .: . : :: :: ::. .:. NP_001 CPNQRGLQRQPSSSRRDSSWSETSEASYSGL 390 400 410 >>XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemokine (415 aa) initn: 788 init1: 444 opt: 845 Z-score: 796.2 bits: 156.1 E(85289): 1.3e-37 Smith-Waterman score: 845; 40.9% identity (68.3% similar) in 357 aa overlap (14-367:67-411) 10 20 30 40 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEG ::.. : .: .: : . :: XP_016 PGLYTAPSSPFPPSQVSDHQVLNDAEVAALLENFSSSYDYGENESD-SCCTSPPCPQ--- 40 50 60 70 80 90 50 60 70 80 90 100 pF1KB8 PLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFI . .: .:.:. :::.::::..:: : ..: .: . :::.:::.:::::: :::. XP_016 DFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLT 100 110 120 130 140 150 110 120 130 140 150 160 pF1KB8 LPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRL ::. .....: ::.:. :::.. :: ..::: ..::::::. :::: ::::.. ::. XP_016 LPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPP 160 170 180 190 200 210 170 180 190 200 210 220 pF1KB8 LSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSL--PRCTFSQENQAETHAWFTSRFL . .:: ..: . .:.:::...: .. ::.. : .: .. . ..: . : : XP_016 ARVTLTCLAVWGLCLLFALPDFIFLSA---HHDERLNATHCQYNFPQVGRT----ALRVL 220 230 240 250 260 230 240 250 260 270 280 pF1KB8 YHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFL :::::::.:::..::. .. : ..: .: .:.:....:. : :::.:::.:... XP_016 QLVAGFLLPLLVMAYCYAHILAVL-LVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLV 270 280 290 300 310 320 290 300 310 320 330 340 pF1KB8 DTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLG : : : :. .: .. . :: .. :: ::::::.::.:.::::: . :: .:: XP_016 DILMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLG 330 340 350 360 370 380 350 360 370 pF1KB8 CTGPASLCQLFPSWRR-SSLSESENATSLTTF : . .: . : :: :: ::. .:. XP_016 CPNQRGLQRQPSSSRRDSSWSETSEASYSGL 390 400 410 >>XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemokine (360 aa) initn: 777 init1: 372 opt: 804 Z-score: 759.0 bits: 149.0 E(85289): 1.5e-35 Smith-Waterman score: 810; 38.3% identity (68.5% similar) in 368 aa overlap (7-372:4-360) 10 20 30 40 50 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEG-PLMASFKAVFVPVAYS ..:. ...:: ::. . :.::. .: . : :. : .. :: . :. XP_005 MEDFNMESDSFED-FWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGT :.:::...:: ::.... : :: :...:..::.::::... ::. .: ::..:: XP_005 LVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFL ::::.: :..:::: . ::::::.::::::::::... ..: : ... : .:: ...: XP_005 FLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL-VKFICLSIWGLSLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAW-FTSRFLYHVAGFLLPMLVMGWCY :::: .:: .. . .: : : .. :. : : . :.: . ::..:.:.: .:: XP_005 LALPVLLFRRTV--YSSNVSPACYEDMGNN--TANWRMLLRILPQSFGFIVPLLIMLFCY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 VGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNG ... : .:. :...:.:: . :. ::.::: ::..:.. ::: : .....::. . XP_005 GFTLRTLFKAHM-GQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRS . :. :.::. : ::::..:.: : ::: : ..:. : . :: :. : XP_005 HIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSL----PKDSRP 300 310 320 330 340 360 370 pF1KB8 SLSESENATSLTTF :. : .. . ::. XP_005 SFVGSSSGHTSTTL 350 360 >>XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemokine (360 aa) initn: 777 init1: 372 opt: 804 Z-score: 759.0 bits: 149.0 E(85289): 1.5e-35 Smith-Waterman score: 810; 38.3% identity (68.5% similar) in 368 aa overlap (7-372:4-360) 10 20 30 40 50 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEG-PLMASFKAVFVPVAYS ..:. ...:: ::. . :.::. .: . : :. : .. :: . :. XP_016 MEDFNMESDSFED-FWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGT :.:::...:: ::.... : :: :...:..::.::::... ::. .: ::..:: XP_016 LVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFL ::::.: :..:::: . ::::::.::::::::::... ..: : ... : .:: ...: XP_016 FLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL-VKFICLSIWGLSLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAW-FTSRFLYHVAGFLLPMLVMGWCY :::: .:: .. . .: : : .. :. : : . :.: . ::..:.:.: .:: XP_016 LALPVLLFRRTV--YSSNVSPACYEDMGNN--TANWRMLLRILPQSFGFIVPLLIMLFCY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 VGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNG ... : .:. :...:.:: . :. ::.::: ::..:.. ::: : .....::. . XP_016 GFTLRTLFKAHM-GQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRS . :. :.::. : ::::..:.: : ::: : ..:. : . :: :. : XP_016 HIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSL----PKDSRP 300 310 320 330 340 360 370 pF1KB8 SLSESENATSLTTF :. : .. . ::. XP_016 SFVGSSSGHTSTTL 350 360 >>XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemokine (360 aa) initn: 777 init1: 372 opt: 804 Z-score: 759.0 bits: 149.0 E(85289): 1.5e-35 Smith-Waterman score: 810; 38.3% identity (68.5% similar) in 368 aa overlap (7-372:4-360) 10 20 30 40 50 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEG-PLMASFKAVFVPVAYS ..:. ...:: ::. . :.::. .: . : :. : .. :: . :. XP_016 MEDFNMESDSFED-FWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGT :.:::...:: ::.... : :: :...:..::.::::... ::. .: ::..:: XP_016 LVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFL ::::.: :..:::: . ::::::.::::::::::... ..: : ... : .:: ...: XP_016 FLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL-VKFICLSIWGLSLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAW-FTSRFLYHVAGFLLPMLVMGWCY :::: .:: .. . .: : : .. :. : : . :.: . ::..:.:.: .:: XP_016 LALPVLLFRRTV--YSSNVSPACYEDMGNN--TANWRMLLRILPQSFGFIVPLLIMLFCY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 VGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNG ... : .:. :...:.:: . :. ::.::: ::..:.. ::: : .....::. . XP_016 GFTLRTLFKAHM-GQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRS . :. :.::. : ::::..:.: : ::: : ..:. : . :: :. : XP_016 HIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSL----PKDSRP 300 310 320 330 340 360 370 pF1KB8 SLSESENATSLTTF :. : .. . ::. XP_016 SFVGSSSGHTSTTL 350 360 >>NP_001548 (OMIM: 146928) C-X-C chemokine receptor type (360 aa) initn: 777 init1: 372 opt: 804 Z-score: 759.0 bits: 149.0 E(85289): 1.5e-35 Smith-Waterman score: 810; 38.3% identity (68.5% similar) in 368 aa overlap (7-372:4-360) 10 20 30 40 50 pF1KB8 MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEG-PLMASFKAVFVPVAYS ..:. ...:: ::. . :.::. .: . : :. : .. :: . :. NP_001 MEDFNMESDSFED-FWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYA 10 20 30 40 50 60 70 80 90 100 110 pF1KB8 LIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGT :.:::...:: ::.... : :: :...:..::.::::... ::. .: ::..:: NP_001 LVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGT 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 FLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFL ::::.: :..:::: . ::::::.::::::::::... ..: : ... : .:: ...: NP_001 FLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL-VKFICLSIWGLSLL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 LALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAW-FTSRFLYHVAGFLLPMLVMGWCY :::: .:: .. . .: : : .. :. : : . :.: . ::..:.:.: .:: NP_001 LALPVLLFRRTV--YSSNVSPACYEDMGNN--TANWRMLLRILPQSFGFIVPLLIMLFCY 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 VGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNG ... : .:. :...:.:: . :. ::.::: ::..:.. ::: : .....::. . NP_001 GFTLRTLFKAHM-GQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRN 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 SLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRS . :. :.::. : ::::..:.: : ::: : ..:. : . :: :. : NP_001 HIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSL----PKDSRP 300 310 320 330 340 360 370 pF1KB8 SLSESENATSLTTF :. : .. . ::. NP_001 SFVGSSSGHTSTTL 350 360 372 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:47:10 2016 done: Fri Nov 4 16:47:11 2016 Total Scan time: 7.530 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]