FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8978, 374 aa 1>>>pF1KB8978 374 - 374 aa - 374 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9475+/-0.000412; mu= 18.9890+/- 0.026 mean_var=104.0127+/-25.546, 0's: 0 Z-trim(111.9): 607 B-trim: 1139 in 1/53 Lambda= 0.125757 statistics sampled from 19854 (20581) to 19854 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.241), width: 16 Scan time: 7.890 The best scores are: opt bits E(85289) NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 2513 467.1 2.8e-131 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 2098 391.8 1.3e-108 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 2098 391.8 1.3e-108 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 1569 295.8 9.8e-80 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 1569 295.8 9.8e-80 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 1253 238.5 1.8e-62 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 1152 220.2 5.9e-57 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 1152 220.2 5.9e-57 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 1152 220.2 5.9e-57 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 1152 220.2 5.9e-57 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 1152 220.2 6.1e-57 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 1152 220.2 6.1e-57 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 1152 220.3 6.4e-57 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 1152 220.3 6.4e-57 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 1099 210.6 4.7e-54 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 1099 210.6 4.7e-54 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 958 185.0 2.3e-46 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 917 177.6 4e-44 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 917 177.6 4e-44 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 917 177.6 4e-44 NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 917 177.6 4.2e-44 XP_016862925 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 831 161.9 2e-39 NP_003956 (OMIM: 608379) C-C chemokine receptor-li ( 344) 831 161.9 2e-39 XP_011532511 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 831 161.9 2e-39 XP_011532510 (OMIM: 608379) PREDICTED: C-C chemoki ( 344) 831 161.9 2e-39 NP_001124382 (OMIM: 608379) C-C chemokine receptor ( 356) 831 162.0 2e-39 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 782 153.1 1e-36 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 779 152.5 1.4e-36 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 779 152.5 1.4e-36 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 779 152.5 1.4e-36 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 779 152.6 1.4e-36 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 755 148.2 2.8e-35 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 755 148.2 2.8e-35 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 755 148.2 2.9e-35 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 755 148.2 2.9e-35 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 735 144.6 3.6e-34 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 735 144.6 3.6e-34 NP_001288643 (OMIM: 600242) C-C chemokine receptor ( 315) 731 143.7 5.4e-34 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 710 140.0 8.1e-33 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 710 140.0 8.1e-33 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 709 139.8 9.3e-33 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 709 139.8 9.3e-33 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 709 139.8 9.3e-33 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 709 139.8 9.3e-33 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 709 139.8 9.3e-33 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 709 139.8 9.3e-33 XP_016861690 (OMIM: 600552) PREDICTED: chemokine X ( 333) 699 138.0 3.1e-32 XP_016861687 (OMIM: 600552) PREDICTED: chemokine X ( 333) 699 138.0 3.1e-32 XP_016861688 (OMIM: 600552) PREDICTED: chemokine X ( 333) 699 138.0 3.1e-32 XP_016861689 (OMIM: 600552) PREDICTED: chemokine X ( 333) 699 138.0 3.1e-32 >>NP_001116513 (OMIM: 601267) C-C chemokine receptor typ (374 aa) initn: 2513 init1: 2513 opt: 2513 Z-score: 2477.8 bits: 467.1 E(85289): 2.8e-131 Smith-Waterman score: 2513; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI 310 320 330 340 350 360 370 pF1KB8 GRAPEASLQDKEGA :::::::::::::: NP_001 GRAPEASLQDKEGA 370 >>NP_001116868 (OMIM: 601267) C-C chemokine receptor typ (360 aa) initn: 2098 init1: 2098 opt: 2098 Z-score: 2071.0 bits: 391.8 E(85289): 1.3e-108 Smith-Waterman score: 2098; 98.4% identity (99.1% similar) in 318 aa overlap (1-318:1-318) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI ::::::::::::: . . NP_001 NPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPSTGEQEVSAGL 310 320 330 340 350 360 >>XP_011532371 (OMIM: 601267) PREDICTED: C-C chemokine r (360 aa) initn: 2098 init1: 2098 opt: 2098 Z-score: 2071.0 bits: 391.8 E(85289): 1.3e-108 Smith-Waterman score: 2098; 98.4% identity (99.1% similar) in 318 aa overlap (1-318:1-318) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTGLY 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFTK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CQKEDSVYVCGPYFPRGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNEKKRHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGMTHCCI 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRGKGKSI ::::::::::::: . . XP_011 NPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTSTNTPSTGEQEVSAGL 310 320 330 340 350 360 >>NP_000570 (OMIM: 601373,609532,610379,612522) C-C chem (352 aa) initn: 1571 init1: 890 opt: 1569 Z-score: 1552.5 bits: 295.8 E(85289): 9.8e-80 Smith-Waterman score: 1569; 75.2% identity (90.4% similar) in 311 aa overlap (21-325:7-317) 10 20 30 40 50 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDY--GAPCHKFDVKQIGAQLLPPLYSLVFIFGFV . ..: .: . ::.:..::::.:.::::::::::::::: NP_000 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFV 10 20 30 40 60 70 80 90 100 110 pF1KB8 GNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTG :::::.:::::::.:: .:::::::::::::.::.:.:.::: :: .: :::.::.:.:: NP_000 GNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTG 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 LYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIF :: ::.:.:::::::::::::::.:::::::::::::::::::::::.::::::.::::: NP_000 LYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIF 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 TKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRN :. ::: :.:. .:: . :.::.:. :::::::::.::::::::::::::::: NP_000 TRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRN 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 EKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLG :::::::::.::::::::::::.:::::.:::::::::::.:: :...:::: ::::::: NP_000 EKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLG 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 MTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGR :::::::::::::::::::. . . . .:: NP_000 MTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQ 290 300 310 320 330 340 360 370 pF1KB8 GKGKSIGRAPEASLQDKEGA NP_000 EISVGL 350 >>NP_001093638 (OMIM: 601373,609532,610379,612522) C-C c (352 aa) initn: 1571 init1: 890 opt: 1569 Z-score: 1552.5 bits: 295.8 E(85289): 9.8e-80 Smith-Waterman score: 1569; 75.2% identity (90.4% similar) in 311 aa overlap (21-325:7-317) 10 20 30 40 50 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDY--GAPCHKFDVKQIGAQLLPPLYSLVFIFGFV . ..: .: . ::.:..::::.:.::::::::::::::: NP_001 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFV 10 20 30 40 60 70 80 90 100 110 pF1KB8 GNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEWVFGNAMCKLFTG :::::.:::::::.:: .:::::::::::::.::.:.:.::: :: .: :::.::.:.:: NP_001 GNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTG 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB8 LYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIF :: ::.:.:::::::::::::::.:::::::::::::::::::::::.::::::.::::: NP_001 LYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIF 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB8 TKCQKEDSVYVCGPYFPRG----WNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRN :. ::: :.:. .:: . :.::.:. :::::::::.::::::::::::::::: NP_001 TRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRN 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 EKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLG :::::::::.::::::::::::.:::::.:::::::::::.:: :...:::: ::::::: NP_001 EKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLG 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB8 MTHCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGR :::::::::::::::::::. . . . .:: NP_001 MTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQ 290 300 310 320 330 340 360 370 pF1KB8 GKGKSIGRAPEASLQDKEGA NP_001 EISVGL 350 >>NP_001286 (OMIM: 601159) C-C chemokine receptor type 1 (355 aa) initn: 1100 init1: 412 opt: 1253 Z-score: 1242.6 bits: 238.5 E(85289): 1.8e-62 Smith-Waterman score: 1253; 57.7% identity (85.0% similar) in 319 aa overlap (12-325:5-321) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN ::.:. ..:: ::: ..::.: . . .:::::::::::::..:.::: NP_001 METPNTTED-YDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGN 10 20 30 40 50 70 80 90 100 110 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWA-HSAANEWVFGNAMCKLFTGL .::::.:.. :.:: .:.::::::::::::::.:::.: .. ..::::.::::...:. NP_001 ILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 YHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFT :. : .. ::::::::::::::::::::::.::::::::.::.: : .:..::.::. :. NP_001 YYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFS 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 KCQKEDSVYVCGPYFP----RGWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNE : : : . ..:. .:: : :. :... :..:::::::.:.:::.::.: ::: :: NP_001 KTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNE 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 KKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGM :: .:::.::.:::..::::::::..::...::.:. .::.. .:: :.::::.... NP_001 KKS-KAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 THCCINPIIYAFVGEKFRSLFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLLDGRG ::::.::.:::::::.::. .. . :.: NP_001 THCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHEL 300 310 320 330 340 350 >>XP_006713023 (OMIM: 601268) PREDICTED: C-C chemokine r (355 aa) initn: 994 init1: 379 opt: 1152 Z-score: 1143.5 bits: 220.2 E(85289): 5.9e-57 Smith-Waterman score: 1152; 54.2% identity (83.7% similar) in 306 aa overlap (21-317:14-317) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN :...: : : :.: :.. . ::..:::::::: :..:: XP_006 MTTSLDTVETFGTTSYYD-DVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGN 10 20 30 40 50 70 80 90 100 110 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSA-ANEWVFGNAMCKLFTGL ..::.:::. ..:. .:.::::::::::::::.:::.: : . ...::::..::::..:. XP_006 VVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 YHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFT :: : .. ::::::::::::::::::::::.::::::::.::..:: .::.:..: .:: XP_006 YHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 KCQKEDSVYVCGPYFPR----GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNE . .. .:. .:. .: .:::. .:. ::::::.:.:::.::.:::::: . XP_006 ETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS- 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 KKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGM ::...:.:.::.:: :.:.::::::..:::...: .. ..:: ...:: . :::.... XP_006 KKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 THCCINPIIYAFVGEKFRS----LFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLL .:::.::.:::::::.::. .:: XP_006 SHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPEL 300 310 320 330 340 350 >>XP_011531637 (OMIM: 601268) PREDICTED: C-C chemokine r (355 aa) initn: 994 init1: 379 opt: 1152 Z-score: 1143.5 bits: 220.2 E(85289): 5.9e-57 Smith-Waterman score: 1152; 54.2% identity (83.7% similar) in 306 aa overlap (21-317:14-317) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN :...: : : :.: :.. . ::..:::::::: :..:: XP_011 MTTSLDTVETFGTTSYYD-DVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGN 10 20 30 40 50 70 80 90 100 110 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSA-ANEWVFGNAMCKLFTGL ..::.:::. ..:. .:.::::::::::::::.:::.: : . ...::::..::::..:. XP_011 VVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 YHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFT :: : .. ::::::::::::::::::::::.::::::::.::..:: .::.:..: .:: XP_011 YHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 KCQKEDSVYVCGPYFPR----GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNE . .. .:. .:. .: .:::. .:. ::::::.:.:::.::.:::::: . XP_011 ETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS- 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 KKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGM ::...:.:.::.:: :.:.::::::..:::...: .. ..:: ...:: . :::.... XP_011 KKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 THCCINPIIYAFVGEKFRS----LFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLL .:::.::.:::::::.::. .:: XP_011 SHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPEL 300 310 320 330 340 350 >>NP_001828 (OMIM: 601268) C-C chemokine receptor type 3 (355 aa) initn: 994 init1: 379 opt: 1152 Z-score: 1143.5 bits: 220.2 E(85289): 5.9e-57 Smith-Waterman score: 1152; 54.2% identity (83.7% similar) in 306 aa overlap (21-317:14-317) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN :...: : : :.: :.. . ::..:::::::: :..:: NP_001 MTTSLDTVETFGTTSYYD-DVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGN 10 20 30 40 50 70 80 90 100 110 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSA-ANEWVFGNAMCKLFTGL ..::.:::. ..:. .:.::::::::::::::.:::.: : . ...::::..::::..:. NP_001 VVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 YHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFT :: : .. ::::::::::::::::::::::.::::::::.::..:: .::.:..: .:: NP_001 YHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 KCQKEDSVYVCGPYFPR----GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNE . .. .:. .:. .: .:::. .:. ::::::.:.:::.::.:::::: . NP_001 ETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS- 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 KKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGM ::...:.:.::.:: :.:.::::::..:::...: .. ..:: ...:: . :::.... NP_001 KKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 THCCINPIIYAFVGEKFRS----LFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLL .:::.::.:::::::.::. .:: NP_001 SHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPEL 300 310 320 330 340 350 >>NP_847899 (OMIM: 601268) C-C chemokine receptor type 3 (355 aa) initn: 994 init1: 379 opt: 1152 Z-score: 1143.5 bits: 220.2 E(85289): 5.9e-57 Smith-Waterman score: 1152; 54.2% identity (83.7% similar) in 306 aa overlap (21-317:14-317) 10 20 30 40 50 60 pF1KB8 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAPCHKFDVKQIGAQLLPPLYSLVFIFGFVGN :...: : : :.: :.. . ::..:::::::: :..:: NP_847 MTTSLDTVETFGTTSYYD-DVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGN 10 20 30 40 50 70 80 90 100 110 pF1KB8 MLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSA-ANEWVFGNAMCKLFTGL ..::.:::. ..:. .:.::::::::::::::.:::.: : . ...::::..::::..:. NP_847 VVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 YHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWLVAVFASVPGIIFT :: : .. ::::::::::::::::::::::.::::::::.::..:: .::.:..: .:: NP_847 YHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFY 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 KCQKEDSVYVCGPYFPR----GWNNFHTIMRNILGLVLPLLIMVICYSGILKTLLRCRNE . .. .:. .:. .: .:::. .:. ::::::.:.:::.::.:::::: . NP_847 ETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPS- 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB8 KKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQATQVTETLGM ::...:.:.::.:: :.:.::::::..:::...: .. ..:: ...:: . :::.... NP_847 KKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAY 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB8 THCCINPIIYAFVGEKFRS----LFHIALGCRIAPLQKPVCGGPGVRPGKNVKVTTQGLL .:::.::.:::::::.::. .:: NP_847 SHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPEL 300 310 320 330 340 350 374 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:47:49 2016 done: Fri Nov 4 16:47:50 2016 Total Scan time: 7.890 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]