FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8980, 376 aa 1>>>pF1KB8980 376 - 376 aa - 376 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.5036+/-0.000329; mu= 4.9659+/- 0.021 mean_var=229.2237+/-45.931, 0's: 0 Z-trim(123.1): 196 B-trim: 36 in 1/58 Lambda= 0.084712 statistics sampled from 42104 (42357) to 42104 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.497), width: 16 Scan time: 9.580 The best scores are: opt bits E(85289) NP_006726 (OMIM: 604685,612290) homeobox protein H ( 376) 2513 319.3 9.1e-87 NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [ ( 356) 866 118.0 3.4e-26 XP_005257332 (OMIM: 142967) PREDICTED: homeobox pr ( 247) 457 67.9 2.9e-11 XP_011509368 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 401 61.2 5.1e-09 XP_005246567 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 401 61.2 5.1e-09 XP_011509367 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 401 61.2 5.1e-09 XP_005246566 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 401 61.2 5.1e-09 XP_005246570 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 401 61.2 5.1e-09 XP_006712540 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 401 61.2 5.1e-09 NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [ ( 432) 401 61.2 5.1e-09 XP_005246568 (OMIM: 142980) PREDICTED: homeobox pr ( 432) 401 61.2 5.1e-09 NP_109377 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 394 60.4 9.3e-09 NP_705895 (OMIM: 142954) homeobox protein Hox-A3 i ( 443) 394 60.4 9.3e-09 XP_005249789 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 394 60.4 9.3e-09 XP_005249787 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 394 60.4 9.3e-09 XP_005249788 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 394 60.4 9.3e-09 XP_011513645 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 394 60.4 9.3e-09 XP_006715778 (OMIM: 142954) PREDICTED: homeobox pr ( 443) 394 60.4 9.3e-09 XP_011523023 (OMIM: 142966) PREDICTED: homeobox pr ( 430) 360 56.2 1.6e-07 NP_001317252 (OMIM: 142966) homeobox protein Hox-B ( 299) 356 55.6 1.8e-07 NP_001317251 (OMIM: 142966) homeobox protein Hox-B ( 358) 356 55.7 2e-07 XP_011523028 (OMIM: 142966) PREDICTED: homeobox pr ( 358) 356 55.7 2e-07 XP_011523022 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 356 55.7 2.3e-07 XP_011523012 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 356 55.7 2.3e-07 XP_005257334 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 356 55.7 2.3e-07 NP_002137 (OMIM: 142966) homeobox protein Hox-B3 i ( 431) 356 55.7 2.3e-07 XP_006721917 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 356 55.7 2.3e-07 XP_011523021 (OMIM: 142966) PREDICTED: homeobox pr ( 431) 356 55.7 2.3e-07 XP_011523010 (OMIM: 142966) PREDICTED: homeobox pr ( 488) 356 55.8 2.5e-07 XP_011523009 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 XP_016880047 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 XP_016880050 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 XP_016880052 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 XP_016880046 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 XP_016880049 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 XP_016880051 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 XP_016880048 (OMIM: 142966) PREDICTED: homeobox pr ( 578) 356 55.9 2.8e-07 NP_055436 (OMIM: 142981) homeobox protein Hox-D4 [ ( 255) 346 54.3 3.7e-07 NP_061975 (OMIM: 142952) homeobox protein Hox-A5 [ ( 270) 334 52.9 1.1e-06 NP_076920 (OMIM: 142965) homeobox protein Hox-B4 [ ( 251) 330 52.3 1.4e-06 NP_002138 (OMIM: 142960) homeobox protein Hox-B5 [ ( 269) 325 51.8 2.3e-06 NP_705897 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 324 51.6 2.4e-06 NP_055435 (OMIM: 142974) homeobox protein Hox-C4 [ ( 264) 324 51.6 2.4e-06 NP_004493 (OMIM: 142962) homeobox protein Hox-B7 [ ( 217) 312 50.1 5.8e-06 NP_002132 (OMIM: 142953) homeobox protein Hox-A4 [ ( 320) 314 50.5 6.5e-06 NP_002135 (OMIM: 142968,614744) homeobox protein H ( 301) 313 50.3 6.7e-06 NP_663632 (OMIM: 616542) GS homeobox 1 [Homo sapie ( 264) 310 49.9 7.9e-06 NP_061826 (OMIM: 142973) homeobox protein Hox-C5 [ ( 222) 307 49.5 9e-06 NP_076919 (OMIM: 142951) homeobox protein Hox-A6 [ ( 233) 306 49.4 1e-05 NP_573574 (OMIM: 616253) GS homeobox 2 [Homo sapie ( 304) 303 49.1 1.6e-05 >>NP_006726 (OMIM: 604685,612290) homeobox protein Hox-A (376 aa) initn: 2513 init1: 2513 opt: 2513 Z-score: 1678.7 bits: 319.3 E(85289): 9.1e-87 Smith-Waterman score: 2513; 100.0% identity (100.0% similar) in 376 aa overlap (1-376:1-376) 10 20 30 40 50 60 pF1KB8 MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 DLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 GALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 GALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPNCLST 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 MGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MGQNCGAGLNNDSPEALEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDISADSLD 310 320 330 340 350 360 370 pF1KB8 FFTDTLTTIDLQHLNY :::::::::::::::: NP_006 FFTDTLTTIDLQHLNY 370 >>NP_002136 (OMIM: 142967) homeobox protein Hox-B2 [Homo (356 aa) initn: 921 init1: 716 opt: 866 Z-score: 591.2 bits: 118.0 E(85289): 3.4e-26 Smith-Waterman score: 1037; 50.3% identity (67.5% similar) in 378 aa overlap (1-372:1-354) 10 20 30 40 50 60 pF1KB8 MNYEFEREIGFINSQPSLAECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLN ::.::::::::::::::::::::::: : .:::.:::: ::: :::::::.:::. NP_002 MNFEFEREIGFINSQPSLAECLTSFPAVLETFQTSSIKESTLIPP---PPPFEQTFPSLQ 10 20 30 40 50 70 80 90 100 110 pF1KB8 PGSHP--RHGAGGRPKPSPAGSRGSPVPAGALQP-PEYPWMKEKKAAKKTALLPAAAAAA ::. : . : . .:: : : : : ::.:::::::.::: . .. . : NP_002 PGASTLQRPRSQKRAEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB8 TAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA ..:. . . : ..: . ...:::.:::::::::::::::::::::::::::::::::: NP_002 ASAVPASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB8 ALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCK-SLEDSEKVEEDEEEKTLFEQA :::::::::::::::::::::::::: .: ..: : .::: . . :: : NP_002 ALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALED---ICDPAEEP-----A 180 190 200 210 220 240 250 260 270 280 290 pF1KB8 LSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNEKNLKHFQHQSPTVPN : .: : .. . . .:.. ..: . . : ... . . :. NP_002 ASPGGPSASRAAW--EACCHPPEVVPGALSADPRPLAV-----------RLEGAGASSPG 230 240 250 260 270 300 310 320 330 340 350 pF1KB8 C-LSTMGQNCGAGLNNDSPEA-LEVPSLQDFSVFSTDSCLQLSDAVSPSLPGSLDSPVDI : : : . : .: . . : : :.. :..::::::: ..:::: ::::::: . NP_002 CALRGAGGLEPGPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGGLSPSLQGSLDSPVPF 280 290 300 310 320 330 360 370 pF1KB8 SADSLDFFTDTLTTIDLQHLNY : . :::::.:: .:::: NP_002 SEEELDFFTSTLCAIDLQFP 340 350 >>XP_005257332 (OMIM: 142967) PREDICTED: homeobox protei (247 aa) initn: 655 init1: 450 opt: 457 Z-score: 323.1 bits: 67.9 E(85289): 2.9e-11 Smith-Waterman score: 628; 49.0% identity (66.7% similar) in 243 aa overlap (133-372:24-245) 110 120 130 140 150 160 pF1KB8 AAKKTALLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEF : . ...:::.::::::::::::::::::: XP_005 MLCPDPGRGCRLERERRKPKSNGLGLPEAGGGGARRLRTAYTNTQLLELEKEF 10 20 30 40 50 170 180 190 200 210 220 pF1KB8 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKCK-SLEDSE ::::::::::::::::::::::::::::::::::::::::: .: ..: : .::: XP_005 HFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALED-- 60 70 80 90 100 110 230 240 250 260 270 280 pF1KB8 KVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQQQAPNGHNGDSQSFPVSPLTSNE . . :: : : .: : .. . . .:.. ..: . . : XP_005 -ICDPAEEP-----AASPGGPSASRAAW--EACCHPPEVVPGALSADPRPLAV------- 120 130 140 150 290 300 310 320 330 pF1KB8 KNLKHFQHQSPTVPNC-LSTMGQNCGAGLNNDSPEA-LEVPSLQDFSVFSTDSCLQLSDA ... . . :.: : : . : .: . . : : :.. :..::::::: . XP_005 ----RLEGAGASSPGCALRGAGGLEPGPLPEDVFSGRQDSPFLPDLNFFAADSCLQLSGG 160 170 180 190 200 210 340 350 360 370 pF1KB8 VSPSLPGSLDSPVDISADSLDFFTDTLTTIDLQHLNY .:::: ::::::: .: . :::::.:: .:::: XP_005 LSPSLQGSLDSPVPFSEEELDFFTSTLCAIDLQFP 220 230 240 >>XP_011509368 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 575 init1: 359 opt: 401 Z-score: 283.0 bits: 61.2 E(85289): 5.1e-09 Smith-Waterman score: 435; 44.6% identity (66.9% similar) in 157 aa overlap (49-205:121-256) 20 30 40 50 60 70 pF1KB8 AECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA ::: :.: :.: : . .:: : .: XP_011 MRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP-----PTLPPSS-PTNPGGGVPAKKPK 100 110 120 130 140 80 90 100 110 120 130 pF1KB8 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG :. .. ..... .:::::.. .: .: . :: : . XP_011 GGPNASSSSATISKQIFPWMKESRQNSKQK---------------NSCATAGESCEDKSP 150 160 170 180 140 150 160 170 180 190 pF1KB8 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH : .:.:.:::::..::.:::::::::.:::::::::.: ::.:::::.:.::::::::. XP_011 PGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQ :.. . : XP_011 KKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNM 250 260 270 280 290 300 >>XP_005246567 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 575 init1: 359 opt: 401 Z-score: 283.0 bits: 61.2 E(85289): 5.1e-09 Smith-Waterman score: 435; 44.6% identity (66.9% similar) in 157 aa overlap (49-205:121-256) 20 30 40 50 60 70 pF1KB8 AECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA ::: :.: :.: : . .:: : .: XP_005 MRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP-----PTLPPSS-PTNPGGGVPAKKPK 100 110 120 130 140 80 90 100 110 120 130 pF1KB8 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG :. .. ..... .:::::.. .: .: . :: : . XP_005 GGPNASSSSATISKQIFPWMKESRQNSKQK---------------NSCATAGESCEDKSP 150 160 170 180 140 150 160 170 180 190 pF1KB8 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH : .:.:.:::::..::.:::::::::.:::::::::.: ::.:::::.:.::::::::. XP_005 PGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQ :.. . : XP_005 KKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNM 250 260 270 280 290 300 >>XP_011509367 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 575 init1: 359 opt: 401 Z-score: 283.0 bits: 61.2 E(85289): 5.1e-09 Smith-Waterman score: 435; 44.6% identity (66.9% similar) in 157 aa overlap (49-205:121-256) 20 30 40 50 60 70 pF1KB8 AECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA ::: :.: :.: : . .:: : .: XP_011 MRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP-----PTLPPSS-PTNPGGGVPAKKPK 100 110 120 130 140 80 90 100 110 120 130 pF1KB8 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG :. .. ..... .:::::.. .: .: . :: : . XP_011 GGPNASSSSATISKQIFPWMKESRQNSKQK---------------NSCATAGESCEDKSP 150 160 170 180 140 150 160 170 180 190 pF1KB8 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH : .:.:.:::::..::.:::::::::.:::::::::.: ::.:::::.:.::::::::. XP_011 PGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQ :.. . : XP_011 KKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNM 250 260 270 280 290 300 >>XP_005246566 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 575 init1: 359 opt: 401 Z-score: 283.0 bits: 61.2 E(85289): 5.1e-09 Smith-Waterman score: 435; 44.6% identity (66.9% similar) in 157 aa overlap (49-205:121-256) 20 30 40 50 60 70 pF1KB8 AECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA ::: :.: :.: : . .:: : .: XP_005 MRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP-----PTLPPSS-PTNPGGGVPAKKPK 100 110 120 130 140 80 90 100 110 120 130 pF1KB8 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG :. .. ..... .:::::.. .: .: . :: : . XP_005 GGPNASSSSATISKQIFPWMKESRQNSKQK---------------NSCATAGESCEDKSP 150 160 170 180 140 150 160 170 180 190 pF1KB8 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH : .:.:.:::::..::.:::::::::.:::::::::.: ::.:::::.:.::::::::. XP_005 PGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQ :.. . : XP_005 KKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNM 250 260 270 280 290 300 >>XP_005246570 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 575 init1: 359 opt: 401 Z-score: 283.0 bits: 61.2 E(85289): 5.1e-09 Smith-Waterman score: 435; 44.6% identity (66.9% similar) in 157 aa overlap (49-205:121-256) 20 30 40 50 60 70 pF1KB8 AECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA ::: :.: :.: : . .:: : .: XP_005 MRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP-----PTLPPSS-PTNPGGGVPAKKPK 100 110 120 130 140 80 90 100 110 120 130 pF1KB8 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG :. .. ..... .:::::.. .: .: . :: : . XP_005 GGPNASSSSATISKQIFPWMKESRQNSKQK---------------NSCATAGESCEDKSP 150 160 170 180 140 150 160 170 180 190 pF1KB8 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH : .:.:.:::::..::.:::::::::.:::::::::.: ::.:::::.:.::::::::. XP_005 PGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQ :.. . : XP_005 KKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNM 250 260 270 280 290 300 >>XP_006712540 (OMIM: 142980) PREDICTED: homeobox protei (432 aa) initn: 575 init1: 359 opt: 401 Z-score: 283.0 bits: 61.2 E(85289): 5.1e-09 Smith-Waterman score: 435; 44.6% identity (66.9% similar) in 157 aa overlap (49-205:121-256) 20 30 40 50 60 70 pF1KB8 AECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA ::: :.: :.: : . .:: : .: XP_006 MRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP-----PTLPPSS-PTNPGGGVPAKKPK 100 110 120 130 140 80 90 100 110 120 130 pF1KB8 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG :. .. ..... .:::::.. .: .: . :: : . XP_006 GGPNASSSSATISKQIFPWMKESRQNSKQK---------------NSCATAGESCEDKSP 150 160 170 180 140 150 160 170 180 190 pF1KB8 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH : .:.:.:::::..::.:::::::::.:::::::::.: ::.:::::.:.::::::::. XP_006 PGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQ :.. . : XP_006 KKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNM 250 260 270 280 290 300 >>NP_008829 (OMIM: 142980) homeobox protein Hox-D3 [Homo (432 aa) initn: 575 init1: 359 opt: 401 Z-score: 283.0 bits: 61.2 E(85289): 5.1e-09 Smith-Waterman score: 435; 44.6% identity (66.9% similar) in 157 aa overlap (49-205:121-256) 20 30 40 50 60 70 pF1KB8 AECLTSFPPVADTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPRHGAGGRPKPSPA ::: :.: :.: : . .:: : .: NP_008 MRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP-----PTLPPSS-PTNPGGGVPAKKPK 100 110 120 130 140 80 90 100 110 120 130 pF1KB8 GSRGSPVPAGALQPPEYPWMKEKKAAKKTALLPAAAAAATAAATGPACLSHKESLEIADG :. .. ..... .:::::.. .: .: . :: : . NP_008 GGPNASSSSATISKQIFPWMKESRQNSKQK---------------NSCATAGESCEDKSP 150 160 170 180 140 150 160 170 180 190 pF1KB8 SGGGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKH : .:.:.:::::..::.:::::::::.:::::::::.: ::.:::::.:.::::::::. NP_008 PGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKY 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB8 KRQTQCKENQNSEGKCKSLEDSEKVEEDEEEKTLFEQALSVSGALLEREGYTFQQNALSQ :.. . : NP_008 KKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPPAFAKSQPNM 250 260 270 280 290 300 376 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:49:31 2016 done: Fri Nov 4 16:49:32 2016 Total Scan time: 9.580 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]