FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8982, 378 aa 1>>>pF1KB8982 378 - 378 aa - 378 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7619+/-0.00077; mu= 3.0536+/- 0.047 mean_var=208.0123+/-42.072, 0's: 0 Z-trim(116.3): 68 B-trim: 165 in 1/54 Lambda= 0.088926 statistics sampled from 16817 (16885) to 16817 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.519), width: 16 Scan time: 3.410 The best scores are: opt bits E(32554) CCDS4372.1 FOXI1 gene_id:2299|Hs108|chr5 ( 378) 2660 353.1 2.4e-97 CCDS47337.1 FOXI1 gene_id:2299|Hs108|chr5 ( 283) 1386 189.6 3e-48 CCDS7655.2 FOXI2 gene_id:399823|Hs108|chr10 ( 318) 896 126.7 2.8e-29 CCDS77433.1 FOXI3 gene_id:344167|Hs108|chr2 ( 420) 818 116.8 3.5e-26 CCDS4473.1 FOXC1 gene_id:2296|Hs108|chr6 ( 553) 560 83.8 4e-16 CCDS10959.1 FOXL1 gene_id:2300|Hs108|chr16 ( 345) 552 82.6 5.7e-16 CCDS35078.1 FOXE1 gene_id:2304|Hs108|chr9 ( 373) 523 78.9 7.9e-15 CCDS10958.1 FOXC2 gene_id:2303|Hs108|chr16 ( 501) 519 78.5 1.4e-14 CCDS13192.1 FOXS1 gene_id:2307|Hs108|chr20 ( 330) 505 76.6 3.6e-14 CCDS550.1 FOXE3 gene_id:2301|Hs108|chr1 ( 319) 500 75.9 5.4e-14 CCDS624.1 FOXD3 gene_id:27022|Hs108|chr1 ( 478) 492 75.0 1.5e-13 CCDS3105.1 FOXL2 gene_id:668|Hs108|chr3 ( 376) 489 74.6 1.6e-13 CCDS9636.1 FOXG1 gene_id:2290|Hs108|chr14 ( 489) 489 74.7 2e-13 CCDS13147.1 FOXA2 gene_id:3170|Hs108|chr20 ( 457) 487 74.4 2.3e-13 CCDS46585.1 FOXA2 gene_id:3170|Hs108|chr20 ( 463) 487 74.4 2.3e-13 CCDS30708.1 FOXD2 gene_id:2306|Hs108|chr1 ( 495) 486 74.3 2.7e-13 CCDS75259.1 FOXD1 gene_id:2297|Hs108|chr5 ( 465) 480 73.5 4.3e-13 CCDS12677.1 FOXA3 gene_id:3171|Hs108|chr19 ( 350) 466 71.6 1.2e-12 CCDS2117.1 FOXD4L1 gene_id:200350|Hs108|chr2 ( 408) 466 71.7 1.4e-12 CCDS75845.1 FOXD4L4 gene_id:349334|Hs108|chr9 ( 416) 455 70.2 3.7e-12 CCDS47977.1 FOXD4L5 gene_id:653427|Hs108|chr9 ( 416) 455 70.2 3.7e-12 CCDS43833.1 FOXD4L3 gene_id:286380|Hs108|chr9 ( 417) 454 70.1 4e-12 CCDS43826.1 FOXD4L6 gene_id:653404|Hs108|chr9 ( 417) 453 70.0 4.4e-12 CCDS9665.1 FOXA1 gene_id:3169|Hs108|chr14 ( 472) 454 70.2 4.4e-12 CCDS35045.1 FOXB2 gene_id:442425|Hs108|chr9 ( 432) 452 69.9 4.9e-12 CCDS32255.1 FOXB1 gene_id:27023|Hs108|chr15 ( 325) 444 68.8 8e-12 CCDS34975.1 FOXD4 gene_id:2298|Hs108|chr9 ( 439) 445 69.0 9.3e-12 CCDS30689.1 FOXJ3 gene_id:22887|Hs108|chr1 ( 622) 433 67.6 3.5e-11 CCDS4472.1 FOXF2 gene_id:2295|Hs108|chr6 ( 444) 425 66.4 5.5e-11 CCDS10957.2 FOXF1 gene_id:2294|Hs108|chr16 ( 379) 423 66.1 5.9e-11 CCDS11813.1 FOXK2 gene_id:3607|Hs108|chr17 ( 660) 427 66.8 6.3e-11 CCDS32739.1 FOXJ1 gene_id:2302|Hs108|chr17 ( 421) 421 65.9 7.6e-11 CCDS4471.1 FOXQ1 gene_id:94234|Hs108|chr6 ( 403) 420 65.7 8e-11 CCDS34591.1 FOXK1 gene_id:221937|Hs108|chr7 ( 733) 423 66.3 9.8e-11 >>CCDS4372.1 FOXI1 gene_id:2299|Hs108|chr5 (378 aa) initn: 2660 init1: 2660 opt: 2660 Z-score: 1861.3 bits: 353.1 E(32554): 2.4e-97 Smith-Waterman score: 2660; 100.0% identity (100.0% similar) in 378 aa overlap (1-378:1-378) 10 20 30 40 50 60 pF1KB8 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 DSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF 310 320 330 340 350 360 370 pF1KB8 YNSVNTSGVLYPREGTEV :::::::::::::::::: CCDS43 YNSVNTSGVLYPREGTEV 370 >>CCDS47337.1 FOXI1 gene_id:2299|Hs108|chr5 (283 aa) initn: 2000 init1: 1386 opt: 1386 Z-score: 979.7 bits: 189.6 E(32554): 3e-48 Smith-Waterman score: 1814; 74.9% identity (74.9% similar) in 378 aa overlap (1-378:1-283) 10 20 30 40 50 60 pF1KB8 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MSSFDLPAPSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDC 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 FKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPV ::::::::::: CCDS47 FKKVPRDEDDP------------------------------------------------- 190 250 260 270 280 290 300 pF1KB8 DSPKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLV :::::::::::::: CCDS47 ----------------------------------------------AYVSGGSPTSHPLV 200 310 320 330 340 350 360 pF1KB8 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 TPGLSPEPSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHF 210 220 230 240 250 260 370 pF1KB8 YNSVNTSGVLYPREGTEV :::::::::::::::::: CCDS47 YNSVNTSGVLYPREGTEV 270 280 >>CCDS7655.2 FOXI2 gene_id:399823|Hs108|chr10 (318 aa) initn: 867 init1: 799 opt: 896 Z-score: 639.2 bits: 126.7 E(32554): 2.8e-29 Smith-Waterman score: 922; 48.4% identity (67.4% similar) in 341 aa overlap (39-378:17-318) 10 20 30 40 50 60 pF1KB8 PSPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATPNPYLWFNGP :. . . :..: : .. .: :: :.: CCDS76 MATYCDDLGPSSAPPGQAQATAHPPGYEPGDLGAVGGGPLLWVNAP 10 20 30 40 70 80 90 100 110 120 pF1KB8 TMTPPPYLPGPN-ASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYS ...: : ::. : :. .::. ::: . .::.:.::.:: . .:.::..::::::: CCDS76 ALSPKSYASGPGPAPPYAAPSYGAPGPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 YSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD :::::::::..:: ..::::::::::: :::::..::::::::::::::::::::::::: CCDS76 YSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFKKVPRD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 EDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTE :::::::::::::::::::::::::::::::....:... : : . :. : .. CCDS76 EDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRAEASAAVRSGARSVGGAEAPALEPPSAA 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 PQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPE :. :::. :: : . : :...: :.:.: ..:: : : ::. . CCDS76 CLDLQ--ASPS---------PSAPEA-ATCFSGFASAMSA-LAGGLGT-FP---GGLAGD 230 240 250 260 310 320 330 340 350 360 pF1KB8 PSDKTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTS : :. : . .: : : : : .: : .. . .: ::.. CCDS76 FS--FGRRPPTVATHAPQT--LNPSPG--FA---PGHQTAAAGFRLSHL----------- 270 280 290 300 370 pF1KB8 GVLYPREGTEV :: :::::: CCDS76 --LYSREGTEV 310 >>CCDS77433.1 FOXI3 gene_id:344167|Hs108|chr2 (420 aa) initn: 864 init1: 733 opt: 818 Z-score: 583.5 bits: 116.8 E(32554): 3.5e-26 Smith-Waterman score: 977; 44.8% identity (65.7% similar) in 397 aa overlap (40-378:28-420) 10 20 30 40 50 60 pF1KB8 SPPRCSPQFPSIGQEPPEMNLYYENFFHPQGVPSPQRPSFEGGGEYGATP----NPYLWF :.: : . : ..:.: : :::::. CCDS77 MALYCGDNFGVYSQPGLPPPAATAAAPGAPPAARAPY-GLADYAAPPAAAANPYLWL 10 20 30 40 50 70 80 90 pF1KB8 NGPTM-----------------TPPPYLPGPNASPFL--PQAYGV----QRPLL---PSV ::: . ::: :: :.::: : : :. :::. :.. CCDS77 NGPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQPAPAA 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB8 SG-----LGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVA . : ..:::: . :.:.:::.:::::::::::::::..::...::::.:::.:: CCDS77 PASPAAPAGPGELGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSHIYQFVA 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB8 DNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRR :.::::..:::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 DSFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRR 180 190 200 210 220 230 220 230 240 250 260 pF1KB8 KRKRKSDVSS-STASLALEKTESSLPVD-------SPKTTEPQDILDGAS----PGGTTS ::::.:..:. ::.. . :.: .: .:. :. .: . : :: : CCDS77 KRKRRSEASNGSTVAAGTSKSEEGLSSGLGSGVGGKPEEESPSTLLRPSHSPEPPEGTKS 240 250 260 270 280 290 270 280 290 300 310 pF1KB8 SPEKRPSPPPSGAPCLNSFLSSMTAYVSGGS-------PTSHPLVTPGLSPEPSDKTGQN . . .: ...::::.:.::... ..: : :. : : . : . . CCDS77 TASSPGGPMLTSTPCLNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQLPSSGVFSPT 300 310 320 330 340 350 320 330 340 350 360 370 pF1KB8 SLTFNSFSPL--TNLSNHSGG--GDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVLY :.. : . : .: ...: : ... .:.:.. . ::. : :: :.: .....: CCDS77 SISEASADTLQLSNSTSNSTGQRSSYYSPFPAS--TSGGQS-SPFSSPFHNFSMVNSLIY 360 370 380 390 400 410 pF1KB8 PREGTEV ::::.:: CCDS77 PREGSEV 420 >>CCDS4473.1 FOXC1 gene_id:2296|Hs108|chr6 (553 aa) initn: 578 init1: 509 opt: 560 Z-score: 402.9 bits: 83.8 E(32554): 4e-16 Smith-Waterman score: 573; 39.2% identity (58.7% similar) in 288 aa overlap (76-328:40-317) 50 60 70 80 90 100 pF1KB8 RPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLGGS .:.: : . :.. : : :: CCDS44 PNSLGVVPYLGGEQSYYRAAAAAAGGGYTAMPAP-MSVYSHPAHAEQYP--------GGM 10 20 30 40 50 60 110 120 130 140 150 160 pF1KB8 DLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKA .. : : . .:.::::: :::.:::..::::..::. :::.. : :::: .: CCDS44 ARAYGPYTPQPQPKDMVKPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQ 70 80 90 100 110 120 170 180 190 200 210 220 pF1KB8 GWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR--KSD-V :::::::::::::.:: :::::. ::::.::::::. .::.::.: :.:.: :.: : CCDS44 GWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAV 130 140 150 160 170 180 230 240 250 260 pF1KB8 SSSTASLALEKTESSLPVDSPKTTEPQDILDGASPG---------------GTTSSPEKR ... . :. : : .: . :.. :: .:: :: :: . CCDS44 KDKEEKDRLHLKEPPPPGRQPPPAPPEQA-DGNAPGPQPPPVRIQDIKTENGTCPSPPQP 190 200 210 220 230 270 280 290 300 310 pF1KB8 PSPPP---SGA----PCLNSFLSSMTAYVSGGSP-----TSHPLVTPGLS-----PEPSD :: ::. : ..: :: .. ::.:: ...:: : . : :: CCDS44 LSPAAALGSGSAAAVPKIESPDSSSSSLSSGSSPPGSLPSARPLSLDGADSAPPPPAPSA 240 250 260 270 280 290 320 330 340 350 360 370 pF1KB8 KTGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVL ..: :. . .:.: CCDS44 PPPHHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSS 300 310 320 330 340 350 >>CCDS10959.1 FOXL1 gene_id:2300|Hs108|chr16 (345 aa) initn: 576 init1: 493 opt: 552 Z-score: 400.2 bits: 82.6 E(32554): 5.7e-16 Smith-Waterman score: 566; 38.0% identity (58.0% similar) in 324 aa overlap (74-364:7-312) 50 60 70 80 90 100 pF1KB8 PQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAYGVQRPLLPSVSGLG : ::. :::.: :: .:: :: :. CCDS10 MSHLFDPRLPALAASPML-YLYGPERPGLP----LA 10 20 30 110 120 130 140 150 160 pF1KB8 GSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKS . . : .. : . .::::: :::::::. ::..:.::. :::.. : ::::. . CCDS10 FAPAAALAASGRAETPQ--KPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDN 40 50 60 70 80 170 180 190 200 210 pF1KB8 KAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKR------- . :::::::::::::::: ::::.. ::::.:::::: : ::.:::.::.. CCDS10 RQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGP 90 100 110 120 130 140 220 230 240 250 260 pF1KB8 -----KRKSDVSSSTASLALEKTESSLPVDSPKTTE-------PQDILDGASPGGTTSSP :: . . .. : .. :. ..: .. :. .::: :: . : CCDS10 GAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWP 150 160 170 180 190 200 270 280 290 300 310 320 pF1KB8 -EKRPSPPPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGL--SPEPSDKTGQNSLTFNS :. . : . .. : .: .: : :: :. ::. :::. .: CCDS10 GTASPNEDAGDAAQGAAAVAVGQAARTGDGPGS-PL-RPASRSSPKSSDKS-------KS 210 220 230 240 250 260 330 340 350 360 370 pF1KB8 FSPLTNLSNHSG----GGDW----ANPMPTNMLSYGGSVL---SQFSPHFYNSVNTSGVL :: . :....: .:: :.: : . : :.:.: :.. : : :. CCDS10 FSIDSILAGKQGQKPPSGDELLGGAKPGPGGRL--GASLLAASSSLRPPFNASLMLDPHV 270 280 290 300 310 pF1KB8 YPREGTEV CCDS10 QGGFYQLGIPFLSYFPLQVPDTVLHFQ 320 330 340 >>CCDS35078.1 FOXE1 gene_id:2304|Hs108|chr9 (373 aa) initn: 479 init1: 458 opt: 523 Z-score: 379.7 bits: 78.9 E(32554): 7.9e-15 Smith-Waterman score: 523; 37.1% identity (56.5% similar) in 294 aa overlap (72-350:7-283) 50 60 70 80 90 pF1KB8 PSPQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQ-----AYGVQRPLL ::: : :.. . . : :. : CCDS35 MTAESGPPP--PQPEVLATVKEERGETAAGAGVPGE 10 20 30 100 110 120 130 140 150 pF1KB8 PSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADN . : :: ... .. .::::: ::::::: ::..::::. ::..... CCDS35 ATGRGAGGR--------RRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITER 40 50 60 70 80 160 170 180 190 200 210 pF1KB8 FPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKR :::: . :::::::::.::::: :.::. :::::::.:::: : ::..:.: :.: CCDS35 FPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSFLRRR 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB8 KR--KSDVSSSTASLALEKTESSLPVDSPKTTEPQDILDGASPGGTTSSPEKRPS--PPP :: .::.:. : . . .. . . .. :. :: :.. : . :: CCDS35 KRFKRSDLSTYPAYM---HDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPGAVYAGYAPP 150 160 170 180 190 200 280 290 300 310 320 pF1KB8 SGA---PCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPEPSDKTGQNSLTFNSF-SPLTNL : : : : : : : .:: .: :.: :: : : .: : .: :. CCDS35 SLAAPPPVYYPAASPGPCRVFGLVPE-RPL-SPELGPAPSGPGG--SCAFASAGAPATTT 210 220 230 240 250 330 340 350 360 370 pF1KB8 SNHSGGGDWANPM-PTNMLS-YGGSVLSQFSPHFYNSVNTSGVLYPREGTEV . . .: : : :. . . :.: CCDS35 GYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVE 260 270 280 290 300 310 >>CCDS10958.1 FOXC2 gene_id:2303|Hs108|chr16 (501 aa) initn: 521 init1: 492 opt: 519 Z-score: 375.1 bits: 78.5 E(32554): 1.4e-14 Smith-Waterman score: 545; 42.0% identity (63.6% similar) in 250 aa overlap (121-351:70-308) 100 110 120 130 140 150 pF1KB8 VQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIY ::.::::: :::.:::..::.:..::. :: CCDS10 VYSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQNAPEKKITLNGIY 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB8 QYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNG :.. : :::: ..: :::::::::::::.:: :::::. ::::.::::::. .::.:: CCDS10 QFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYWTLDPDSYNMFENG 100 110 120 130 140 150 220 230 240 250 pF1KB8 NFRRKRKR--KSDVSSST---ASL-----ALEKTESSLP--VDSPKTTEPQDIL--DGAS .: :.:.: :.:::. : : : : . : .:.:: .: . .. ..:: CCDS10 SFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAPKEAEKKVVIKSEAAS 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB8 PGGTTSSPEKRPSPPPS--GAPCLNSFLSSMTAYVSGGSPTSH---PLVTPGLSPEPSDK :. . . . :: . :.: : :. .. .:. : : : ::.: : CCDS10 PALPVITKVETLSPESALQGSP--RSAASTPAGSPDGSLPEHHAAAPNGLPGFSVE---- 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB8 TGQNSLTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVLY : .:. . : .:: :.: . .: : :... CCDS10 ---NIMTLRTSPPGGELS--PGAGRAGLVVPPLALPYAAAPPAAYGQPCAQGLEAGAAGG 280 290 300 310 320 pF1KB8 PREGTEV CCDS10 YQCSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSPLSALNLAAGQEGALAATGHH 330 340 350 360 370 380 >>CCDS13192.1 FOXS1 gene_id:2307|Hs108|chr20 (330 aa) initn: 525 init1: 462 opt: 505 Z-score: 367.9 bits: 76.6 E(32554): 3.6e-14 Smith-Waterman score: 505; 36.8% identity (61.6% similar) in 250 aa overlap (110-356:6-248) 80 90 100 110 120 130 pF1KB8 NASPFLPQAYGVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGA :: :. ..::::: :::::::... CCDS13 MQQQPLPGPGAPTTEP-TKPPYSYIALIAMAIQSS 10 20 30 140 150 160 170 180 190 pF1KB8 PDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTL : .: ::: ::.:. : :: ... :::::::::::::.:: :::::. ::::.:::: CCDS13 PGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFVKVPRDDRKPGKGSYWTL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB8 DPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTEPQDI-LDGASPG ::.:. ::..:.: :.:.: . ... .. . :.. . : . :: . .:. : CCDS13 DPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRG-----PLRATSQDPGVPNATTG 100 110 120 130 140 260 270 280 290 300 310 pF1KB8 GTTSSPEKRPSPPP-SGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLS-PEPSDKTGQNS : : . :.: : . .... .:: .. : : :. .: :.:. CCDS13 RQCSFPPELPDPKGLSFGGLVGAMPASMCPATTDGRPRP-PMEPKEISTPKPACPGELPV 150 160 170 180 190 200 320 330 340 350 360 370 pF1KB8 LTFNSFSPLTNLSNHSGGGDWANPMPTNMLSYGGSVLSQFSPHFYNSVNTSGVLYPREGT : .: : .. . .. : :: .:: ... :.. CCDS13 ATSSSSCPAFGFPAGFSEAESFNKAPTPVLSPESGIGSSYQCRLQALNFCMGADPGLEHL 210 220 230 240 250 260 pF1KB8 EV CCDS13 LASAAPSPAPPTPPGSLRAPLPLPTDHKEPWVAGGFPVQGGSGYPLGLTPCLYRTPGMFF 270 280 290 300 310 320 >>CCDS550.1 FOXE3 gene_id:2301|Hs108|chr1 (319 aa) initn: 455 init1: 455 opt: 500 Z-score: 364.7 bits: 75.9 E(32554): 5.4e-14 Smith-Waterman score: 500; 33.8% identity (55.5% similar) in 308 aa overlap (60-358:8-301) 30 40 50 60 70 80 pF1KB8 LYYENFFHPQGVPSPQRPSFEGGGEYGATPNPYLWFNGPTMTPPPYLPGPNASPFLPQAY .: :.: : :: ::. CCDS55 MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEP 10 20 30 90 100 110 120 130 140 pF1KB8 GVQRPLLPSVSGLGGSDLGWLPIPSQEELMKLVR--PPYSYSALIAMAIHGAPDKRLTLS : : ...: : . : :.... : : ::::: ::::::. :: .::::. CCDS55 G--REPEEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLA 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB8 QIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMF ::..... : :: : :::::::::.::::: ::::. .::::::::::: :: CCDS55 AIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMF 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB8 DNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTEPQDILDGASPGGTTSSPEKR :::.: :.::: . . . . : .: .: . : .:. . : CCDS55 DNGSFLRRRKRFKRAELPAHAAAAPGPPLPFPY-APYAPAP-------GPALLVPPPSAG 160 170 180 190 200 270 280 290 300 310 320 pF1KB8 PSP-PPSGAPCLNSFLSSMTAYVSGGSPTSHPLVTPGLSPE---PSDKTGQNSLTFNSFS :.: ::. ..:... . .. :.: ..: . : ... : . . CCDS55 PGPSPPARLFSVDSLVNLQPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPD 210 220 230 240 250 260 330 340 350 360 370 pF1KB8 PLTNLSNHSGGGDWANPMPTN-MLSYGG--SVLSQFSPHFYNSVNTSGVLYPREGTEV :. ... : : :.:.. .:. .: ..:. .:: CCDS55 RLVLPATRPGPG----PLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL 270 280 290 300 310 378 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:50:08 2016 done: Fri Nov 4 16:50:09 2016 Total Scan time: 3.410 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]