FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8985, 387 aa 1>>>pF1KB8985 387 - 387 aa - 387 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.9474+/-0.000412; mu= -4.6578+/- 0.025 mean_var=345.8332+/-75.527, 0's: 0 Z-trim(121.9): 1652 B-trim: 3900 in 2/55 Lambda= 0.068967 statistics sampled from 37016 (39128) to 37016 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.459), width: 16 Scan time: 8.170 The best scores are: opt bits E(85289) NP_004421 (OMIM: 602419) early growth response pro ( 387) 2704 282.8 9.7e-76 XP_011542731 (OMIM: 602419) PREDICTED: early growt ( 406) 2382 250.7 4.4e-66 NP_001186809 (OMIM: 602419) early growth response ( 349) 2380 250.5 4.6e-66 XP_005273483 (OMIM: 602419) PREDICTED: early growt ( 349) 2380 250.5 4.6e-66 XP_005273482 (OMIM: 602419) PREDICTED: early growt ( 442) 2380 250.6 5.4e-66 NP_001186810 (OMIM: 602419) early growth response ( 333) 2362 248.7 1.5e-65 NP_001955 (OMIM: 128990) early growth response pro ( 543) 968 110.2 1.2e-23 NP_001129651 (OMIM: 129010,145900,605253,607678) E ( 426) 768 90.2 1e-17 NP_001307966 (OMIM: 129010,145900,605253,607678) E ( 426) 768 90.2 1e-17 NP_001129649 (OMIM: 129010,145900,605253,607678) E ( 476) 768 90.2 1.1e-17 NP_000390 (OMIM: 129010,145900,605253,607678) E3 S ( 476) 768 90.2 1.1e-17 NP_001129650 (OMIM: 129010,145900,605253,607678) E ( 476) 768 90.2 1.1e-17 XP_011537729 (OMIM: 129010,145900,605253,607678) P ( 489) 768 90.2 1.1e-17 NP_001956 (OMIM: 128992) early growth response pro ( 589) 574 71.0 8.1e-12 NP_001185480 (OMIM: 106210,136680,156240,194070,19 ( 302) 427 56.1 1.3e-07 NP_000369 (OMIM: 106210,136680,156240,194070,19407 ( 497) 427 56.3 1.8e-07 NP_077742 (OMIM: 106210,136680,156240,194070,19407 ( 514) 427 56.3 1.9e-07 NP_001185481 (OMIM: 106210,136680,156240,194070,19 ( 288) 411 54.5 3.8e-07 NP_077744 (OMIM: 106210,136680,156240,194070,19407 ( 517) 411 54.7 5.7e-07 XP_006711416 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 XP_006711421 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 XP_006711419 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 XP_011507901 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 XP_006711412 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 NP_001243384 (OMIM: 607646) zinc finger and BTB do ( 539) 355 49.2 2.8e-05 XP_006711420 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 XP_006711422 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 XP_006711417 (OMIM: 607646) PREDICTED: zinc finger ( 539) 355 49.2 2.8e-05 NP_001239335 (OMIM: 607646) zinc finger and BTB do ( 573) 355 49.2 2.9e-05 XP_011507900 (OMIM: 607646) PREDICTED: zinc finger ( 573) 355 49.2 2.9e-05 XP_016856888 (OMIM: 607646) PREDICTED: zinc finger ( 630) 355 49.3 3.1e-05 NP_037512 (OMIM: 603994) zinc finger protein 112 i ( 907) 348 48.7 6.4e-05 NP_001076804 (OMIM: 603994) zinc finger protein 11 ( 913) 348 48.7 6.5e-05 XP_016867772 (OMIM: 603989) PREDICTED: zinc finger ( 783) 346 48.5 6.7e-05 XP_016867774 (OMIM: 603989) PREDICTED: zinc finger ( 783) 346 48.5 6.7e-05 NP_057304 (OMIM: 603989) zinc finger protein 107 i ( 783) 346 48.5 6.7e-05 XP_016867775 (OMIM: 603989) PREDICTED: zinc finger ( 783) 346 48.5 6.7e-05 NP_001013768 (OMIM: 603989) zinc finger protein 10 ( 783) 346 48.5 6.7e-05 XP_016867773 (OMIM: 603989) PREDICTED: zinc finger ( 783) 346 48.5 6.7e-05 NP_001269289 (OMIM: 603989) zinc finger protein 10 ( 820) 346 48.5 6.9e-05 NP_001269288 (OMIM: 603989) zinc finger protein 10 ( 852) 346 48.5 7.1e-05 XP_016878355 (OMIM: 604752) PREDICTED: zinc finger ( 487) 337 47.4 9e-05 NP_008894 (OMIM: 194529) zinc finger protein 22 [H ( 224) 329 46.2 9.1e-05 XP_011511865 (OMIM: 194648,615226) PREDICTED: zinc ( 398) 333 46.9 0.0001 NP_003432 (OMIM: 194648,615226) zinc finger protei ( 474) 333 46.9 0.00012 XP_016878354 (OMIM: 604752) PREDICTED: zinc finger ( 711) 337 47.5 0.00012 NP_001252517 (OMIM: 604752) zinc finger protein 26 ( 711) 337 47.5 0.00012 NP_003405 (OMIM: 604752) zinc finger protein 267 i ( 743) 337 47.5 0.00012 XP_011511864 (OMIM: 194648,615226) PREDICTED: zinc ( 502) 333 47.0 0.00012 XP_016864080 (OMIM: 194648,615226) PREDICTED: zinc ( 534) 333 47.0 0.00013 >>NP_004421 (OMIM: 602419) early growth response protein (387 aa) initn: 2704 init1: 2704 opt: 2704 Z-score: 1480.7 bits: 282.8 E(85289): 9.7e-76 Smith-Waterman score: 2704; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KB8 MTGKLAEKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MTGKLAEKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 NEKPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NEKPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 STQTSTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 STQTSTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 PALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 PGFGSLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PGFGSLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 GHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 GHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKE 310 320 330 340 350 360 370 380 pF1KB8 KKAEKGGAPSASSAPPVSLAPVVTTCA ::::::::::::::::::::::::::: NP_004 KKAEKGGAPSASSAPPVSLAPVVTTCA 370 380 >>XP_011542731 (OMIM: 602419) PREDICTED: early growth re (406 aa) initn: 2380 init1: 2380 opt: 2382 Z-score: 1307.3 bits: 250.7 E(85289): 4.4e-66 Smith-Waterman score: 2382; 94.7% identity (96.6% similar) in 358 aa overlap (30-387:49-406) 10 20 30 40 50 pF1KB8 MTGKLAEKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGL :.. .: : .. . . :::::::: XP_011 PTHSSRPPRSRRLGWRRHGRGFGSPGWGQPPTGGSLPPGMEPCAAWSPRGGRENVMDIGL 20 30 40 50 60 70 60 70 80 90 100 110 pF1KB8 TNEKPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TNEKPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGA 80 90 100 110 120 130 120 130 140 150 160 170 pF1KB8 LSTQTSTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSTQTSTASMVQPPQGDVEAMYPALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSA 140 150 160 170 180 190 180 190 200 210 220 230 pF1KB8 KPALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KPALDSNLFPMIPDYNLYHHPNDMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQI 200 210 220 230 240 250 240 250 260 270 280 290 pF1KB8 HPGFGSLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HPGFGSLPQPPLTLKPIRPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIH 260 270 280 290 300 310 300 310 320 330 340 350 pF1KB8 TGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQK 320 330 340 350 360 370 360 370 380 pF1KB8 EKKAEKGGAPSASSAPPVSLAPVVTTCA :::::::::::::::::::::::::::: XP_011 EKKAEKGGAPSASSAPPVSLAPVVTTCA 380 390 400 >>NP_001186809 (OMIM: 602419) early growth response prot (349 aa) initn: 2380 init1: 2380 opt: 2380 Z-score: 1307.1 bits: 250.5 E(85289): 4.6e-66 Smith-Waterman score: 2380; 100.0% identity (100.0% similar) in 336 aa overlap (52-387:14-349) 30 40 50 60 70 80 pF1KB8 DNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKPNPELSYSGSFQPAPGNK :::::::::::::::::::::::::::::: NP_001 MEPCAAWSPRGGRENVMDIGLTNEKPNPELSYSGSFQPAPGNK 10 20 30 40 90 100 110 120 130 140 pF1KB8 TVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMY 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB8 PALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPN 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB8 DMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKY 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB8 PNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLT 230 240 250 260 270 280 330 340 350 360 370 380 pF1KB8 THIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 THIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAP 290 300 310 320 330 340 pF1KB8 VVTTCA :::::: NP_001 VVTTCA >>XP_005273483 (OMIM: 602419) PREDICTED: early growth re (349 aa) initn: 2380 init1: 2380 opt: 2380 Z-score: 1307.1 bits: 250.5 E(85289): 4.6e-66 Smith-Waterman score: 2380; 100.0% identity (100.0% similar) in 336 aa overlap (52-387:14-349) 30 40 50 60 70 80 pF1KB8 DNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKPNPELSYSGSFQPAPGNK :::::::::::::::::::::::::::::: XP_005 MEPCAAWSPRGGRENVMDIGLTNEKPNPELSYSGSFQPAPGNK 10 20 30 40 90 100 110 120 130 140 pF1KB8 TVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMY 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB8 PALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPN 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB8 DMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKY 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB8 PNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLT 230 240 250 260 270 280 330 340 350 360 370 380 pF1KB8 THIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAP 290 300 310 320 330 340 pF1KB8 VVTTCA :::::: XP_005 VVTTCA >>XP_005273482 (OMIM: 602419) PREDICTED: early growth re (442 aa) initn: 2380 init1: 2380 opt: 2380 Z-score: 1305.8 bits: 250.6 E(85289): 5.4e-66 Smith-Waterman score: 2380; 100.0% identity (100.0% similar) in 336 aa overlap (52-387:107-442) 30 40 50 60 70 80 pF1KB8 DNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKPNPELSYSGSFQPAPGNK :::::::::::::::::::::::::::::: XP_005 GSETTCSCSYLPAPPREEQQCFSRARACVCENVMDIGLTNEKPNPELSYSGSFQPAPGNK 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB8 TVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVTYLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMY 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB8 PALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PALPPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPN 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB8 DMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DMGSIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKY 260 270 280 290 300 310 270 280 290 300 310 320 pF1KB8 PNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLT 320 330 340 350 360 370 330 340 350 360 370 380 pF1KB8 THIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 THIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAP 380 390 400 410 420 430 pF1KB8 VVTTCA :::::: XP_005 VVTTCA 440 >>NP_001186810 (OMIM: 602419) early growth response prot (333 aa) initn: 2362 init1: 2362 opt: 2362 Z-score: 1297.6 bits: 248.7 E(85289): 1.5e-65 Smith-Waterman score: 2362; 100.0% identity (100.0% similar) in 333 aa overlap (55-387:1-333) 30 40 50 60 70 80 pF1KB8 YPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKPNPELSYSGSFQPAPGNKTVT :::::::::::::::::::::::::::::: NP_001 MDIGLTNEKPNPELSYSGSFQPAPGNKTVT 10 20 30 90 100 110 120 130 140 pF1KB8 YLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMYPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLGKFAFDSPSNWCQDNIISLMSAGILGVPPASGALSTQTSTASMVQPPQGDVEAMYPAL 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB8 PPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPNDMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PPYSNCGDLYSEPVSFHDPQGNPGLAYSPQDYQSAKPALDSNLFPMIPDYNLYHHPNDMG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB8 SIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKYPNR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SIPEHKPFQGMDPIRVNPPPITPLETIKAFKDKQIHPGFGSLPQPPLTLKPIRPRKYPNR 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB8 PSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHI 220 230 240 250 260 270 330 340 350 360 370 380 pF1KB8 RTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSAPPVSLAPVVT 280 290 300 310 320 330 pF1KB8 TCA ::: NP_001 TCA >>NP_001955 (OMIM: 128990) early growth response protein (543 aa) initn: 1043 init1: 716 opt: 968 Z-score: 545.4 bits: 110.2 E(85289): 1.2e-23 Smith-Waterman score: 1025; 48.7% identity (70.0% similar) in 380 aa overlap (31-385:81-449) 10 20 30 40 50 pF1KB8 MTGKLAEKLPVTMSSLLNQLPDNLYPEEIPSALNLFSGSSDSVVH-YNQMATENVMDIGL :. . :. ..:. . :.....:. ::.: NP_001 AAGAPEGSGSNSSSSSSGGGGGGGGGSNSSSSSSTFNPQADTGEQPYEHLTAESFPDISL 60 70 80 90 100 110 60 70 80 90 100 110 pF1KB8 TNEKPNPELSYSGSFQPAPGNKTVTYLGKFAFDSPSN-----WCQDNIISLMSAGILGV- .::: : :: .. : .:: :.:... : : . ..::.: :.... NP_001 NNEKVLVETSYPSQTTRLP---PITYTGRFSLEPAPNSGNTLW-PEPLFSLVS-GLVSMT 120 130 140 150 160 120 130 140 150 160 pF1KB8 -PPASG--ALSTQTSTASMVQ-PP------QGDVEAMYPALPPY-SNCGDLYSEPVSFHD ::::. : : .:.:: : :: ..: .: : : . . :.. :: : NP_001 NPPASSSSAPSPAASSASASQSPPLSCAVPSNDSSPIYSAAPTFPTPNTDIFPEPQSQAF 170 180 190 200 210 220 170 180 190 200 210 pF1KB8 PQGNPGLA--YSPQDYQSAKPALDSNLFPMIPDYNLYHHPNDMG-SIPEHKPFQGMDPIR : :. : : : : : .:: ... :::::: . .. .:.: . :..:::::.. : NP_001 P-GSAGTALQYPPPAYPAAKGGFQ---VPMIPDYLFPQQQGDLGLGTPDQKPFQGLES-R 230 240 250 260 270 280 220 230 240 250 260 270 pF1KB8 VNPPPITPLETIKAFKDKQIHPGFGSLP---QPPLTLKPIRPRKYPNRPSKTPLHERPHA .. : .::: ::::: .. . .: : : .:: : ::::::::::: ::::.: NP_001 TQQPSLTPLSTIKAFATQSGSQDLKALNTSYQSQL-IKPSRMRKYPNRPSKTPPHERPYA 290 300 310 320 330 280 290 300 310 320 330 pF1KB8 CPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSFSRSDHLTTHIRTHTGEKPFACE ::.:.::::::::::::::.:::::.::::::::::.::::::::::::::::::::::. NP_001 CPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACD 340 350 360 370 380 390 340 350 360 370 380 pF1KB8 FCGRKFARSDERKRHAKIHLKQKEKKAEKGG-APSASSAPPVSLAPVVTTCA .::::::::::::::.::::.::.:::.:. : ::.:. .::.:. NP_001 ICGRKFARSDERKRHTKIHLRQKDKKADKSVVASSATSSLSSYPSPVATSYPSPVTTSYP 400 410 420 430 440 450 NP_001 SPATTSYPSPVPTSFSSPGSSTYPSPVHSGFPSPSVATTYSSVPPAFPAQVSSFPSSAVT 460 470 480 490 500 510 >>NP_001129651 (OMIM: 129010,145900,605253,607678) E3 SU (426 aa) initn: 1136 init1: 731 opt: 768 Z-score: 439.2 bits: 90.2 E(85289): 1e-17 Smith-Waterman score: 1124; 51.1% identity (68.7% similar) in 403 aa overlap (47-387:2-394) 20 30 40 50 60 70 pF1KB8 LNQLPDNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKPNPELSYSGSFQP : .: .....: .:.:: . .: : .:: : NP_001 MNGVAGDGMINIDMTGEKRSLDLPYPSSFAP 10 20 30 80 90 100 110 120 pF1KB8 --APGNKTVTYLGKFAFDS--PSNWCQ-DNIISLMSAGIL-GVP-PASGALSTQTSTAS- :: :.: ::.:::..: :. : ..::...::::: :: ::: . :.....:: NP_001 VSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASP 40 50 60 70 80 90 130 140 150 160 170 pF1KB8 --MVQPPQG---------DVEAMY---PALPPYSNC-GDLYSEPVSFHDP---QGNPGLA .. : : :.. .: : ::::.: ::::..: .: . . . .:: NP_001 NPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLA 100 110 120 130 140 150 180 190 200 210 220 pF1KB8 YSPQ-DYQSAKPALDSNLFPMIPDYNLYHHPN----DM-GSI-PEHKPFQ-GMDPIRVNP : : .: : ::: : .:::::::: . :. :. :. :..::: .: .:: : NP_001 YPPPPSYPSPKPATDPGLFPMIPDYPGFF-PSQCQRDLHGTAGPDRKPFPCPLDTLRV-P 160 170 180 190 200 230 240 250 pF1KB8 PPITPLETIKAF-----KDKQIHPGF--GSL-PQPP-------------------LTLKP ::.::: ::. : . :: :: :. : : :.: NP_001 PPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRP 210 220 230 240 250 260 260 270 280 290 300 310 pF1KB8 I-RPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSF : :::::::::::::.::::. :::::::::::::::::::.::::::::::::::::.: NP_001 ILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNF 270 280 290 300 310 320 320 330 340 350 360 370 pF1KB8 SRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSA :::::::::::::::::::::..::::::::::::::.::::.:::.:. .::::: . NP_001 SRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKS---SAPSAS-V 330 340 350 360 370 380 380 pF1KB8 PPVSLAPVVTTCA : :: ...:. NP_001 P----APSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 390 400 410 420 >>NP_001307966 (OMIM: 129010,145900,605253,607678) E3 SU (426 aa) initn: 1136 init1: 731 opt: 768 Z-score: 439.2 bits: 90.2 E(85289): 1e-17 Smith-Waterman score: 1124; 51.1% identity (68.7% similar) in 403 aa overlap (47-387:2-394) 20 30 40 50 60 70 pF1KB8 LNQLPDNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKPNPELSYSGSFQP : .: .....: .:.:: . .: : .:: : NP_001 MNGVAGDGMINIDMTGEKRSLDLPYPSSFAP 10 20 30 80 90 100 110 120 pF1KB8 --APGNKTVTYLGKFAFDS--PSNWCQ-DNIISLMSAGIL-GVP-PASGALSTQTSTAS- :: :.: ::.:::..: :. : ..::...::::: :: ::: . :.....:: NP_001 VSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSASP 40 50 60 70 80 90 130 140 150 160 170 pF1KB8 --MVQPPQG---------DVEAMY---PALPPYSNC-GDLYSEPVSFHDP---QGNPGLA .. : : :.. .: : ::::.: ::::..: .: . . . .:: NP_001 NPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSSLA 100 110 120 130 140 150 180 190 200 210 220 pF1KB8 YSPQ-DYQSAKPALDSNLFPMIPDYNLYHHPN----DM-GSI-PEHKPFQ-GMDPIRVNP : : .: : ::: : .:::::::: . :. :. :. :..::: .: .:: : NP_001 YPPPPSYPSPKPATDPGLFPMIPDYPGFF-PSQCQRDLHGTAGPDRKPFPCPLDTLRV-P 160 170 180 190 200 230 240 250 pF1KB8 PPITPLETIKAF-----KDKQIHPGF--GSL-PQPP-------------------LTLKP ::.::: ::. : . :: :: :. : : :.: NP_001 PPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPLRP 210 220 230 240 250 260 260 270 280 290 300 310 pF1KB8 I-RPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMRSF : :::::::::::::.::::. :::::::::::::::::::.::::::::::::::::.: NP_001 ILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMRNF 270 280 290 300 310 320 320 330 340 350 360 370 pF1KB8 SRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSASSA :::::::::::::::::::::..::::::::::::::.::::.:::.:. .::::: . NP_001 SRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKS---SAPSAS-V 330 340 350 360 370 380 380 pF1KB8 PPVSLAPVVTTCA : :: ...:. NP_001 P----APSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 390 400 410 420 >>NP_001129649 (OMIM: 129010,145900,605253,607678) E3 SU (476 aa) initn: 1228 init1: 731 opt: 768 Z-score: 438.6 bits: 90.2 E(85289): 1.1e-17 Smith-Waterman score: 1125; 50.9% identity (68.9% similar) in 405 aa overlap (45-387:50-444) 20 30 40 50 60 70 pF1KB8 SLLNQLPDNLYPEEIPSALNLFSGSSDSVVHYNQMATENVMDIGLTNEKPNPELSYSGSF ..: .: .....: .:.:: . .: : .:: NP_001 QLSDNIYPVEDLAATSVTIFPNAELGGPFDQMNGVAGDGMINIDMTGEKRSLDLPYPSSF 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 QP--APGNKTVTYLGKFAFDS--PSNWCQ-DNIISLMSAGIL-GVP-PASGALSTQTSTA : :: :.: ::.:::..: :. : ..::...::::: :: ::: . :.....: NP_001 APVSAPRNQTFTYMGKFSIDPQYPGASCYPEGIINIVSAGILQGVTSPASTTASSSVTSA 80 90 100 110 120 130 130 140 150 160 pF1KB8 S---MVQPPQG---------DVEAMY---PALPPYSNC-GDLYSEPVSFHDP---QGNPG : .. : : :.. .: : ::::.: ::::..: .: . . . . NP_001 SPNPLATGPLGVCTMSQTQPDLDHLYSPPPPPPPYSGCAGDLYQDPSAFLSAATTSTSSS 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB8 LAYSPQ-DYQSAKPALDSNLFPMIPDYNLYHHPN----DM-GSI-PEHKPFQ-GMDPIRV ::: : .: : ::: : .:::::::: . :. :. :. :..::: .: .:: NP_001 LAYPPPPSYPSPKPATDPGLFPMIPDYPGFF-PSQCQRDLHGTAGPDRKPFPCPLDTLRV 200 210 220 230 240 250 230 240 250 pF1KB8 NPPPITPLETIKAF-----KDKQIHPGF--GSL-PQPP-------------------LTL :::.::: ::. : . :: :: :. : : : NP_001 -PPPLTPLSTIRNFTLGGPSAGVTGPGASGGSEGPRLPGSSSAAAAAAAAAAYNPHHLPL 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB8 KPI-RPRKYPNRPSKTPLHERPHACPAEGCDRRFSRSDELTRHLRIHTGHKPFQCRICMR .:: :::::::::::::.::::. :::::::::::::::::::.:::::::::::::::: NP_001 RPILRPRKYPNRPSKTPVHERPYPCPAEGCDRRFSRSDELTRHIRIHTGHKPFQCRICMR 320 330 340 350 360 370 320 330 340 350 360 370 pF1KB8 SFSRSDHLTTHIRTHTGEKPFACEFCGRKFARSDERKRHAKIHLKQKEKKAEKGGAPSAS .::::::::::::::::::::::..::::::::::::::.::::.:::.:. .::::: NP_001 NFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKS---SAPSAS 380 390 400 410 420 430 380 pF1KB8 SAPPVSLAPVVTTCA .: :: ...:. NP_001 -VP----APSTASCSGGVQPGGTLCSSNSSSLGGGPLAPCSSRTRTP 440 450 460 470 387 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:28:11 2016 done: Sat Nov 5 08:28:12 2016 Total Scan time: 8.170 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]