FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8986, 387 aa 1>>>pF1KB8986 387 - 387 aa - 387 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7932+/-0.000568; mu= 20.0645+/- 0.035 mean_var=128.7730+/-33.433, 0's: 0 Z-trim(108.0): 595 B-trim: 804 in 1/48 Lambda= 0.113022 statistics sampled from 15383 (16085) to 15383 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.525), E-opt: 0.2 (0.189), width: 16 Scan time: 7.330 The best scores are: opt bits E(85289) NP_001164645 (OMIM: 601470,607339,609423,613784) C ( 387) 2538 426.3 5.8e-119 NP_001328 (OMIM: 601470,607339,609423,613784) CX3C ( 355) 2335 393.2 5.1e-109 NP_001164643 (OMIM: 601470,607339,609423,613784) C ( 355) 2335 393.2 5.1e-109 NP_001164642 (OMIM: 601470,607339,609423,613784) C ( 355) 2335 393.2 5.1e-109 XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 941 165.9 1.4e-40 NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 941 165.9 1.4e-40 NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 931 164.3 4.2e-40 XP_011532371 (OMIM: 601267) PREDICTED: C-C chemoki ( 360) 921 162.6 1.3e-39 NP_001116868 (OMIM: 601267) C-C chemokine receptor ( 360) 921 162.6 1.3e-39 NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 920 162.5 1.5e-39 NP_001116513 (OMIM: 601267) C-C chemokine receptor ( 374) 912 161.2 3.7e-39 NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 902 159.5 1.1e-38 XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 902 159.5 1.1e-38 NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 902 159.5 1.1e-38 XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 902 159.5 1.1e-38 NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 902 159.6 1.1e-38 NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 902 159.6 1.2e-38 XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 902 159.6 1.2e-38 XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 902 159.6 1.2e-38 NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 887 157.1 6.1e-38 NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 887 157.1 6.1e-38 NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 728 131.2 4e-30 NP_003458 (OMIM: 162643,193670) C-X-C chemokine re ( 352) 723 130.3 6.8e-30 NP_001008540 (OMIM: 162643,193670) C-X-C chemokine ( 356) 723 130.3 6.8e-30 NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 698 126.3 1.2e-28 NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 698 126.3 1.2e-28 NP_005274 (OMIM: 600552) chemokine XC receptor 1 [ ( 333) 688 124.6 3.4e-28 XP_016861686 (OMIM: 600552) PREDICTED: chemokine X ( 333) 688 124.6 3.4e-28 XP_016861685 (OMIM: 600552) PREDICTED: chemokine X ( 333) 688 124.6 3.4e-28 XP_016861689 (OMIM: 600552) PREDICTED: chemokine X ( 333) 688 124.6 3.4e-28 XP_016861688 (OMIM: 600552) PREDICTED: chemokine X ( 333) 688 124.6 3.4e-28 NP_001019815 (OMIM: 600552) chemokine XC receptor ( 333) 688 124.6 3.4e-28 XP_016861687 (OMIM: 600552) PREDICTED: chemokine X ( 333) 688 124.6 3.4e-28 XP_016861690 (OMIM: 600552) PREDICTED: chemokine X ( 333) 688 124.6 3.4e-28 NP_848540 (OMIM: 606065) atypical chemokine recept ( 350) 682 123.6 7e-28 NP_057641 (OMIM: 606065) atypical chemokine recept ( 350) 682 123.6 7e-28 NP_001288646 (OMIM: 600242) C-C chemokine receptor ( 372) 657 119.6 1.2e-26 NP_001288647 (OMIM: 600242) C-C chemokine receptor ( 372) 657 119.6 1.2e-26 NP_001288645 (OMIM: 600242) C-C chemokine receptor ( 372) 657 119.6 1.2e-26 NP_001829 (OMIM: 600242) C-C chemokine receptor ty ( 378) 657 119.6 1.2e-26 NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 631 115.3 2.3e-25 XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 631 115.3 2.3e-25 XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 631 115.3 2.3e-25 NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 631 115.3 2.3e-25 XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 631 115.3 2.3e-25 XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 631 115.3 2.3e-25 NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 630 115.2 2.5e-25 NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 630 115.2 2.5e-25 XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 630 115.2 2.6e-25 NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 630 115.2 2.6e-25 >>NP_001164645 (OMIM: 601470,607339,609423,613784) CX3C (387 aa) initn: 2538 init1: 2538 opt: 2538 Z-score: 2256.7 bits: 426.3 E(85289): 5.8e-119 Smith-Waterman score: 2538; 99.2% identity (99.7% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KB8 MREPLEALKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVV :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MREPLEAFKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 HYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 ISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISLGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 YCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMR ::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::: NP_001 YCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 KDLRLALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSE ::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDLRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSE 310 320 330 340 350 360 370 380 pF1KB8 SQRSRHGSVLSSNFTYHTSDGDALLLL ::::::::::::::::::::::::::: NP_001 SQRSRHGSVLSSNFTYHTSDGDALLLL 370 380 >>NP_001328 (OMIM: 601470,607339,609423,613784) CX3C che (355 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 2078.2 bits: 393.2 E(85289): 5.1e-109 Smith-Waterman score: 2335; 99.4% identity (99.7% similar) in 355 aa overlap (33-387:1-355) 10 20 30 40 50 60 pF1KB8 EPLEALKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVVFG :::::::::::::::::::::::::::::: NP_001 MDQFPESVTENFEYDDLAEACYIGDIVVFG 10 20 30 70 80 90 100 110 120 pF1KB8 TVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 LINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 LGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKD ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_001 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMRKD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB8 LRLALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQ ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQ 280 290 300 310 320 330 370 380 pF1KB8 RSRHGSVLSSNFTYHTSDGDALLLL ::::::::::::::::::::::::: NP_001 RSRHGSVLSSNFTYHTSDGDALLLL 340 350 >>NP_001164643 (OMIM: 601470,607339,609423,613784) CX3C (355 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 2078.2 bits: 393.2 E(85289): 5.1e-109 Smith-Waterman score: 2335; 99.4% identity (99.7% similar) in 355 aa overlap (33-387:1-355) 10 20 30 40 50 60 pF1KB8 EPLEALKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVVFG :::::::::::::::::::::::::::::: NP_001 MDQFPESVTENFEYDDLAEACYIGDIVVFG 10 20 30 70 80 90 100 110 120 pF1KB8 TVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 LINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 LGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKD ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_001 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMRKD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB8 LRLALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQ ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQ 280 290 300 310 320 330 370 380 pF1KB8 RSRHGSVLSSNFTYHTSDGDALLLL ::::::::::::::::::::::::: NP_001 RSRHGSVLSSNFTYHTSDGDALLLL 340 350 >>NP_001164642 (OMIM: 601470,607339,609423,613784) CX3C (355 aa) initn: 2335 init1: 2335 opt: 2335 Z-score: 2078.2 bits: 393.2 E(85289): 5.1e-109 Smith-Waterman score: 2335; 99.4% identity (99.7% similar) in 355 aa overlap (33-387:1-355) 10 20 30 40 50 60 pF1KB8 EPLEALKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVVFG :::::::::::::::::::::::::::::: NP_001 MDQFPESVTENFEYDDLAEACYIGDIVVFG 10 20 30 70 80 90 100 110 120 pF1KB8 TVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHY 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 LINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTIS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB8 LGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGVWAAAILVAAPQFMFTKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB8 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKD ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_001 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNVMIFLETLKLYDFFPSCDMRKD 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB8 LRLALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQ ::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LRLALSVTETVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQ 280 290 300 310 320 330 370 380 pF1KB8 RSRHGSVLSSNFTYHTSDGDALLLL ::::::::::::::::::::::::: NP_001 RSRHGSVLSSNFTYHTSDGDALLLL 340 350 >>XP_016861176 (OMIM: 604836) PREDICTED: C-C chemokine r (360 aa) initn: 933 init1: 453 opt: 941 Z-score: 849.7 bits: 165.9 E(85289): 1.4e-40 Smith-Waterman score: 941; 42.3% identity (71.3% similar) in 352 aa overlap (38-382:13-355) 10 20 30 40 50 60 pF1KB8 LKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFE-YDDLAEACYIGDIVVFGTVFL ::. :. :... . : : .:: .:: XP_016 MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFL 10 20 30 40 70 80 90 100 110 120 pF1KB8 SIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINE .::..:..::.:: .::..: . :. .:.::.::::::.:::::: .:::: .: .. XP_016 PPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 KGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVW . ..::. . ....::...:::. ..::::::::: :. :. ::. .:: ::..: XP_016 WVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATW 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 AAAILVAAPQFMF----TKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC ..:.... : :.: :..... : : . . : :: ..: :.::...:: :: .: XP_016 SVAVFASLPGFLFSTCYTERNHTYCKTKYS-LNSTTWKVLSSLEINILGLVIPLGIMLFC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKD : ::.:: :::.:: ::.:.:. ::..:. :::::::..::::: . . .: ... XP_016 YSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERY 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LRLALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKC--LAVLCGRSVHVDFSSSE : :...:: .:: ::::::.:: : :::::.:. .:. : : ::: ... :.. XP_016 LDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSAD 290 300 310 320 330 340 370 380 pF1KB8 SQRSRHGSVLSSNFTYHTSDGDALLLL . ::..: : : : XP_016 TP--------SSSYTQSTMDHDLHDAL 350 360 >>NP_005499 (OMIM: 604836) C-C chemokine receptor type 4 (360 aa) initn: 933 init1: 453 opt: 941 Z-score: 849.7 bits: 165.9 E(85289): 1.4e-40 Smith-Waterman score: 941; 42.3% identity (71.3% similar) in 352 aa overlap (38-382:13-355) 10 20 30 40 50 60 pF1KB8 LKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFE-YDDLAEACYIGDIVVFGTVFL ::. :. :... . : : .:: .:: NP_005 MNPTDIADTTLDESIYSNYYLYESIPKPCTKEGIKAFGELFL 10 20 30 40 70 80 90 100 110 120 pF1KB8 SIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINE .::..:..::.:: .::..: . :. .:.::.::::::.:::::: .:::: .: .. NP_005 PPLYSLVFVFGLLGNSVVVLVLFKYKRLRSMTDVYLLNLAISDLLFVFSLPFWGYYAADQ 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 KGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVW . ..::. . ....::...:::. ..::::::::: :. :. ::. .:: ::..: NP_005 WVFGLGLCKMISWMYLVGFYSGIFFVMLMSIDRYLAIVHAVFSLRARTLTYGVITSLATW 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 AAAILVAAPQFMF----TKQKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYC ..:.... : :.: :..... : : . . : :: ..: :.::...:: :: .: NP_005 SVAVFASLPGFLFSTCYTERNHTYCKTKYS-LNSTTWKVLSSLEINILGLVIPLGIMLFC 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 YFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKD : ::.:: :::.:: ::.:.:. ::..:. :::::::..::::: . . .: ... NP_005 YSMIIRTLQHCKNEKKNKAVKMIFAVVVLFLGFWTPYNIVLFLETLVELEVLQDCTFERY 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LRLALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKC--LAVLCGRSVHVDFSSSE : :...:: .:: ::::::.:: : :::::.:. .:. : : ::: ... :.. NP_005 LDYAIQATETLAFVHCCLNPIIYFFLGEKFRKYILQLFKTCRGLFVLCQYCGLLQIYSAD 290 300 310 320 330 340 370 380 pF1KB8 SQRSRHGSVLSSNFTYHTSDGDALLLL . ::..: : : : NP_005 TP--------SSSYTQSTMDHDLHDAL 350 360 >>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8 (355 aa) initn: 863 init1: 466 opt: 931 Z-score: 840.9 bits: 164.3 E(85289): 4.2e-40 Smith-Waterman score: 931; 39.7% identity (75.3% similar) in 348 aa overlap (31-372:3-350) 10 20 30 40 50 60 pF1KB8 MREPLEALKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVV .:.: .::. . : .. : : . NP_005 MDYTLDLSVTTVTDYYYPDIFSSPCDAELIQT 10 20 30 70 80 90 100 110 120 pF1KB8 FGTVFLSIFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWT : ..:..:: ..:...:.:: ::...:. :: .:.::.::::::::::::: ..:: : NP_005 NGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSITDVYLLNLALSDLLFVFSFPFQT 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB8 HYLINEKGLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVT .::... . ..::: ...:..:::..:.::::..:.:::::.: :. ... ::.. :.: NP_005 YYLLDQWVFGTVMCKVVSGFYYIGFYSSMFFITLMSVDRYLAVVHAVYALKVRTIRMGTT 100 110 120 130 140 150 190 200 210 220 230 pF1KB8 ISLGVWAAAILVAAPQFMFTK-QKENECLGDYPEVLQEI--WPVLRNVETNFLGFLLPLL . :.:: .::... : ..: . .:. : : :. : .. : . :.::.:.:. NP_005 LCLAVWLTAIMATIPLLVFYQVASEDGVLQCYSFYNQQTLKWKIFTNFKMNILGLLIPFT 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB8 IMSYCYFRIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSC :. .::..:.. : :.::.:.:::.:.:.:::. .:::.:.:...:: .:. . .. .: NP_005 IFMFCYIKILHQLKRCQNHNKTKAIRLVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGC 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB8 DMRKDLRLALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGK-CLAVLC--GRSVHV .. ..: : :::...:.:::.::.::::.::::...: ... : : .. ::.. NP_005 SISQQLTYATHVTEIISFTHCCVNPVIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPR 280 290 300 310 320 330 360 370 380 pF1KB8 DFSSSESQRSRHGSVLSSNFTYHTSDGDALLLL . . :. ..:.: :: NP_005 ESCEKSSSCQQHSSRSSSVDYIL 340 350 >>XP_011532371 (OMIM: 601267) PREDICTED: C-C chemokine r (360 aa) initn: 619 init1: 597 opt: 921 Z-score: 832.1 bits: 162.6 E(85289): 1.3e-39 Smith-Waterman score: 921; 47.2% identity (75.6% similar) in 307 aa overlap (38-342:18-322) 10 20 30 40 50 60 pF1KB8 LKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLS : :: :.:: : :. :. .:. .: XP_011 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAP-CHKFDVKQIGAQLLP 10 20 30 40 70 80 90 100 110 120 pF1KB8 IFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEK .::..: .:.:::.:::. : : :: : .:::::::::.:::::. :::.:.: :: XP_011 PLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEW 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 GLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWA . :::::. :... ::.::.:::: ...:::::::: :. ... ::: ::. :. .: XP_011 VFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 AAILVAAPQFMFTK-QKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRI .:.....: ..::: :::. : . . : .... :.::..:::::: :: : XP_011 VAVFASVPGIIFTKCQKEDSVYVCGP-YFPRGWNNFHTIMRNILGLVLPLLIMVICYSGI 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 IQTLFSCKNHKKA-KAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKDLRL ..::. :.:.:: .:...:. ..::.:::::::::.:.:.:.. . . .:. ..: XP_011 LKTLLRCRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 ALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSR : .::: ....:::.::.::::.:::::::: .. : XP_011 ATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTS 290 300 310 320 330 340 370 380 pF1KB8 HGSVLSSNFTYHTSDGDALLLL XP_011 TNTPSTGEQEVSAGL 350 360 >>NP_001116868 (OMIM: 601267) C-C chemokine receptor typ (360 aa) initn: 619 init1: 597 opt: 921 Z-score: 832.1 bits: 162.6 E(85289): 1.3e-39 Smith-Waterman score: 921; 47.2% identity (75.6% similar) in 307 aa overlap (38-342:18-322) 10 20 30 40 50 60 pF1KB8 LKLADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLS : :: :.:: : :. :. .:. .: NP_001 MLSTSRSRFIRNTNESGEEVTTFFDYDYGAP-CHKFDVKQIGAQLLP 10 20 30 40 70 80 90 100 110 120 pF1KB8 IFYSVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHYLINEK .::..: .:.:::.:::. : : :: : .:::::::::.:::::. :::.:.: :: NP_001 PLYSLVFIFGFVGNMLVVLILINCKKLKCLTDIYLLNLAISDLLFLITLPLWAHSAANEW 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 GLHNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWA . :::::. :... ::.::.:::: ...:::::::: :. ... ::: ::. :. .: NP_001 VFGNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWL 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 AAILVAAPQFMFTK-QKENECLGDYPEVLQEIWPVLRNVETNFLGFLLPLLIMSYCYFRI .:.....: ..::: :::. : . . : .... :.::..:::::: :: : NP_001 VAVFASVPGIIFTKCQKEDSVYVCGP-YFPRGWNNFHTIMRNILGLVLPLLIMVICYSGI 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 IQTLFSCKNHKKA-KAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKDLRL ..::. :.:.:: .:...:. ..::.:::::::::.:.:.:.. . . .:. ..: NP_001 LKTLLRCRNEKKRHRAVRVIFTIMIVYFLFWTPYNIVILLNTFQEFFGLSNCESTSQLDQ 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 ALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRSR : .::: ....:::.::.::::.:::::::: .. : NP_001 ATQVTETLGMTHCCINPIIYAFVGEKFRRYLSVFFRKHITKRFCKQCPVFYRETVDGVTS 290 300 310 320 330 340 370 380 pF1KB8 HGSVLSSNFTYHTSDGDALLLL NP_001 TNTPSTGEQEVSAGL 350 360 >>NP_001286 (OMIM: 601159) C-C chemokine receptor type 1 (355 aa) initn: 892 init1: 451 opt: 920 Z-score: 831.3 bits: 162.5 E(85289): 1.5e-39 Smith-Waterman score: 920; 44.9% identity (76.0% similar) in 312 aa overlap (41-346:13-322) 20 30 40 50 60 70 pF1KB8 ADLDFRKSSLASGWRMASGAFTMDQFPESVTENFEYDDLAEACYIGDIVVFGTVFLSIFY : .:.: : : : . .::. .: .: NP_001 METPNTTEDYDTTTEFDYGD-ATPCQKVNERAFGAQLLPPLY 10 20 30 40 80 90 100 110 120 pF1KB8 SVIFAIGLVGNLLVVFALTNSKKPKSVTDIYLLNLALSDLLFVATLPFWTHY-LINEKGL :..:.::::::.:::..:.. :. :..:.:::::::.:::::. ::::: : : .. . NP_001 SLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVF 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB8 HNAMCKFTTAFFFIGFFGSIFFITVISIDRYLAIVLAANSMNNRTVQHGVTISLGVWAAA .::::. ..:.. :... :::: ...:::::::: :. .. ::: :: :. .:: : NP_001 GDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALA 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB8 ILVAAPQFMFTKQK----ENECLGDYP-EVLQEIWPVLRNVETNFLGFLLPLLIMSYCYF ::.. : ..:.: . .. : .: : :.: : ... .. :..:..::::.: :: NP_001 ILASMPGLYFSKTQWEFTHHTCSLHFPHESLRE-WKLFQALKLNLFGLVLPLLVMIICYT 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB8 RIIQTLFSCKNHKKAKAIKLILLVVIVFFLFWTPYNIMIFLETLKLYDFFPSCDMRKDLR ::. :. :.::.::..::....:.:::::::::. :.. ... . : :.. . : NP_001 GIIKILLRRPNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLD 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB8 LALSVTEMVAFSHCCLNPLIYAFAGEKFRRYLYHLYGKCLAVLCGRSVHVDFSSSESQRS ::..:::..:..:::.::.::::.::.::.:: .:. . .:: NP_001 LAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVS 290 300 310 320 330 340 370 380 pF1KB8 RHGSVLSSNFTYHTSDGDALLLL NP_001 STSPSTGEHELSAGF 350 387 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:39:11 2016 done: Sat Nov 5 01:39:12 2016 Total Scan time: 7.330 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]