FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8990, 391 aa
1>>>pF1KB8990 391 - 391 aa - 391 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9971+/-0.00049; mu= 18.9003+/- 0.030
mean_var=137.0317+/-35.051, 0's: 0 Z-trim(109.1): 641 B-trim: 845 in 1/56
Lambda= 0.109563
statistics sampled from 16416 (17203) to 16416 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.539), E-opt: 0.2 (0.202), width: 16
Scan time: 6.770
The best scores are: opt bits E(85289)
NP_000614 (OMIM: 113503) B2 bradykinin receptor [H ( 391) 2616 426.2 6.7e-119
NP_000701 (OMIM: 600337) B1 bradykinin receptor [H ( 353) 760 132.7 1.3e-30
NP_000677 (OMIM: 300034) type-2 angiotensin II rec ( 363) 658 116.6 9.5e-26
XP_011535835 (OMIM: 300034) PREDICTED: type-2 angi ( 363) 658 116.6 9.5e-26
NP_114438 (OMIM: 106165,145500,267430) type-1 angi ( 388) 615 109.9 1.1e-23
NP_114038 (OMIM: 106165,145500,267430) type-1 angi ( 394) 615 109.9 1.1e-23
NP_004826 (OMIM: 106165,145500,267430) type-1 angi ( 394) 615 109.9 1.1e-23
NP_005192 (OMIM: 601834) C-C chemokine receptor ty ( 355) 611 109.2 1.6e-23
NP_000676 (OMIM: 106165,145500,267430) type-1 angi ( 359) 605 108.2 3.1e-23
NP_033611 (OMIM: 106165,145500,267430) type-1 angi ( 359) 605 108.2 3.1e-23
NP_001286 (OMIM: 601159) C-C chemokine receptor ty ( 355) 600 107.4 5.4e-23
NP_847898 (OMIM: 601268) C-C chemokine receptor ty ( 376) 570 102.7 1.5e-21
XP_016861175 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 570 102.8 1.6e-21
XP_016861174 (OMIM: 601268) PREDICTED: C-C chemoki ( 410) 570 102.8 1.6e-21
NP_001158152 (OMIM: 601268) C-C chemokine receptor ( 373) 567 102.3 2.1e-21
XP_011531637 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 560 101.1 4.3e-21
NP_847899 (OMIM: 601268) C-C chemokine receptor ty ( 355) 560 101.1 4.3e-21
XP_006713023 (OMIM: 601268) PREDICTED: C-C chemoki ( 355) 560 101.1 4.3e-21
NP_001828 (OMIM: 601268) C-C chemokine receptor ty ( 355) 560 101.1 4.3e-21
XP_016859479 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 551 99.7 1.2e-20
XP_016859481 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 551 99.7 1.2e-20
NP_001161770 (OMIM: 146928) C-X-C chemokine recept ( 360) 551 99.7 1.2e-20
NP_001548 (OMIM: 146928) C-X-C chemokine receptor ( 360) 551 99.7 1.2e-20
XP_016859480 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 551 99.7 1.2e-20
XP_005246587 (OMIM: 146928) PREDICTED: C-X-C chemo ( 360) 551 99.7 1.2e-20
NP_006632 (OMIM: 604738) C-C chemokine receptor ty ( 357) 533 96.9 8.3e-20
NP_001243298 (OMIM: 604738) C-C chemokine receptor ( 357) 533 96.9 8.3e-20
XP_011531614 (OMIM: 604738) PREDICTED: C-C chemoki ( 369) 533 96.9 8.5e-20
NP_112477 (OMIM: 604738) C-C chemokine receptor ty ( 369) 533 96.9 8.5e-20
NP_000625 (OMIM: 146929,609423) C-X-C chemokine re ( 350) 530 96.4 1.1e-19
NP_005152 (OMIM: 600052) apelin receptor [Homo sap ( 380) 518 94.5 4.5e-19
NP_000570 (OMIM: 601373,609532,610379,612522) C-C ( 352) 513 93.7 7.4e-19
NP_001093638 (OMIM: 601373,609532,610379,612522) C ( 352) 513 93.7 7.4e-19
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 511 93.4 9.4e-19
NP_001495 (OMIM: 300574) C-X-C chemokine receptor ( 368) 508 92.9 1.3e-18
XP_005262313 (OMIM: 300574) PREDICTED: C-X-C chemo ( 378) 505 92.5 1.8e-18
XP_016884924 (OMIM: 300574) PREDICTED: C-X-C chemo ( 415) 505 92.5 1.9e-18
NP_001136269 (OMIM: 300574) C-X-C chemokine recept ( 415) 505 92.5 1.9e-18
NP_113597 (OMIM: 601835) C-C chemokine receptor ty ( 374) 498 91.4 4e-18
NP_004358 (OMIM: 601835) C-C chemokine receptor ty ( 374) 498 91.4 4e-18
NP_005499 (OMIM: 604836) C-C chemokine receptor ty ( 360) 496 91.0 4.8e-18
XP_016861176 (OMIM: 604836) PREDICTED: C-C chemoki ( 360) 496 91.0 4.8e-18
NP_001287 (OMIM: 602648) atypical chemokine recept ( 384) 494 90.7 6.2e-18
NP_001707 (OMIM: 601613) C-X-C chemokine receptor ( 372) 484 89.1 1.8e-17
NP_116743 (OMIM: 601613) C-X-C chemokine receptor ( 327) 478 88.1 3.3e-17
NP_005287 (OMIM: 300086) lysophosphatidic acid rec ( 370) 468 86.6 1.1e-16
XP_016884927 (OMIM: 300086) PREDICTED: lysophospha ( 370) 468 86.6 1.1e-16
XP_006724702 (OMIM: 300086) PREDICTED: lysophospha ( 370) 468 86.6 1.1e-16
XP_016884926 (OMIM: 300086) PREDICTED: lysophospha ( 370) 468 86.6 1.1e-16
NP_001264929 (OMIM: 300086) lysophosphatidic acid ( 370) 468 86.6 1.1e-16
>>NP_000614 (OMIM: 113503) B2 bradykinin receptor [Homo (391 aa)
initn: 2616 init1: 2616 opt: 2616 Z-score: 2255.6 bits: 426.2 E(85289): 6.7e-119
Smith-Waterman score: 2616; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391)
10 20 30 40 50 60
pF1KB8 MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEP
310 320 330 340 350 360
370 380 390
pF1KB8 IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
:::::::::::::::::::::::::::::::
NP_000 IQMENSMGTLRTSISVERQIHKLQDWAGSRQ
370 380 390
>>NP_000701 (OMIM: 600337) B1 bradykinin receptor [Homo (353 aa)
initn: 702 init1: 567 opt: 760 Z-score: 670.5 bits: 132.7 E(85289): 1.3e-30
Smith-Waterman score: 760; 37.7% identity (68.1% similar) in 326 aa overlap (33-353:10-333)
10 20 30 40 50
pF1KB8 SPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQ--SKCPQV-EWLGWLNTI
::. . . : : . : .. : :. .
NP_000 MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRV
10 20 30
60 70 80 90 100 110
pF1KB8 QPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISN
: :. . .. : :.::: :: : . . .::::::.::::.::... :::::: .: :
NP_000 LPTFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWN
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB8 NFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSL
.:.: :: ::::.:..:. ::. :: ... .: ::: .::. :. :.. : :.. .
NP_000 QFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCV
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB8 VIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSV
.:: ::: : ...:... : :.:::.. : :. . ::..::::::..
NP_000 LIWVVGGLLSIPTFLLRSIQAVPDL--NITACILLLPHEAWHFARIVELNILGFLLPLAA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB8 ITFCTMQIMQVLRNNEMQKFKEI--QTERRATVLVLVVLLLFIICWLPFQISTFLDTLHR
:.: ...:. ::. : . . . . ..:.:.:.... :..:: :... .::. : .
NP_000 IVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB8 LGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCR
. . .: : .::. :.:.:.:..:: :::..::.::. :: : ::.:. :
NP_000 VQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAP
280 290 300 310 320 330
360 370 380 390
pF1KB8 SEPIQMENSMGTLRTSISVERQIHKLQDWAGSRQ
NP_000 ISSSHRKEIFQLFWRN
340 350
>>NP_000677 (OMIM: 300034) type-2 angiotensin II recepto (363 aa)
initn: 531 init1: 304 opt: 658 Z-score: 583.3 bits: 116.6 E(85289): 9.5e-26
Smith-Waterman score: 658; 33.7% identity (65.3% similar) in 323 aa overlap (47-357:35-350)
20 30 40 50 60 70
pF1KB8 SVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENI
: : :..: : . ...::.. : ::
NP_000 STLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAI-PILYYIIFVIGFLVNI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 FVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAI
:...:: .:. :. ::. :::.:::.: ::.:: : .::::: ..:.: ...
NP_000 VVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSF
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB8 ISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSS-PMLVF
...:...:: :. .:.::: ... . ... :. :. ..: : ::: : . :
NP_000 LTLNMFASIFFITCMSVDRYQSVIYPF-LSQRRNPWQASYIVPLVW-CMACLSSLPTFYF
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB8 RTMKEYSDEGHNVTACVISYPS---LIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQ-VL
: .. : :.::....: : . .. :..::..:: :. : . : . .:
NP_000 RDVRTIEYLG--VNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLL
190 200 210 220 230
260 270 280 290 300 310
pF1KB8 RNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIID
..: . : . :. .. .. .:.: ::::::::.. ::::.: .:...::. .::
NP_000 KTNSYGKNR--ITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVID
240 250 260 270 280 290
320 330 340 350 360
pF1KB8 VITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVY-------QGVCQKGGCRSEPIQME
. .: .....:::.::..: .::.::..: :. :: .. .::
NP_000 LALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLRE
300 310 320 330 340 350
370 380 390
pF1KB8 NSMGTLRTSISVERQIHKLQDWAGSRQ
NP_000 METFVS
360
>>XP_011535835 (OMIM: 300034) PREDICTED: type-2 angioten (363 aa)
initn: 531 init1: 304 opt: 658 Z-score: 583.3 bits: 116.6 E(85289): 9.5e-26
Smith-Waterman score: 658; 33.7% identity (65.3% similar) in 323 aa overlap (47-357:35-350)
20 30 40 50 60 70
pF1KB8 SVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENI
: : :..: : . ...::.. : ::
XP_011 STLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAI-PILYYIIFVIGFLVNI
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB8 FVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAI
:...:: .:. :. ::. :::.:::.: ::.:: : .::::: ..:.: ...
XP_011 VVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSF
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB8 ISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSS-PMLVF
...:...:: :. .:.::: ... . ... :. :. ..: : ::: : . :
XP_011 LTLNMFASIFFITCMSVDRYQSVIYPF-LSQRRNPWQASYIVPLVW-CMACLSSLPTFYF
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB8 RTMKEYSDEGHNVTACVISYPS---LIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQ-VL
: .. : :.::....: : . .. :..::..:: :. : . : . .:
XP_011 RDVRTIEYLG--VNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLL
190 200 210 220 230
260 270 280 290 300 310
pF1KB8 RNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIID
..: . : . :. .. .. .:.: ::::::::.. ::::.: .:...::. .::
XP_011 KTNSYGKNR--ITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVID
240 250 260 270 280 290
320 330 340 350 360
pF1KB8 VITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVY-------QGVCQKGGCRSEPIQME
. .: .....:::.::..: .::.::..: :. :: .. .::
XP_011 LALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLRE
300 310 320 330 340 350
370 380 390
pF1KB8 NSMGTLRTSISVERQIHKLQDWAGSRQ
XP_011 METFVS
360
>>NP_114438 (OMIM: 106165,145500,267430) type-1 angioten (388 aa)
initn: 519 init1: 361 opt: 615 Z-score: 546.3 bits: 109.9 E(85289): 1.1e-23
Smith-Waterman score: 615; 31.3% identity (64.3% similar) in 367 aa overlap (22-382:21-380)
10 20 30 40 50
pF1KB8 MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGT-FAQSKCPQVEWLGWLNTI
:. :...... :.. : .: :. ::.. ... ..
NP_114 MLTFTSECGCTTFGVFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHNYIFVM
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 QPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISN
: . ..::.. . : .:. :. .. . ::: ..: ::: ::: . ::.::. .
NP_114 IPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 NFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSL
.. : ::. ::....: .:.:::.:. .: .:::::::.:. :. : . ::. .
NP_114 EYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 VIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSL--IWEVFTNMLLNVVGFLLPL
.:: . : : : .. :.. . :. :.:.:.. : : . .. :..:::.:.
NP_114 IIWLLAGLASLPAIIHRNV--FFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPF
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 SVITFCTMQIMQVLRNN-EMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLH
.: : ..:.. :.:: : . . ......:.:.. :.: :: ::::.:
NP_114 LIILTSYTLIWKALKKAYEIQKNKPRNDD--IFKIIMAIVLFFFFSWIPHQIFTFLDVLI
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 RLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGC
.:::. .:. :.:. :. .:: :.::::: : ..::.:.. .. . . :.
NP_114 QLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKS
300 310 320 330 340 350
360 370 380 390
pF1KB8 RSEPIQMENSMGTL--RTSISVERQIHKLQDWAGSRQ
.:. . ..:.:: : : .: . .:
NP_114 HSN---LSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
360 370 380
>>NP_114038 (OMIM: 106165,145500,267430) type-1 angioten (394 aa)
initn: 519 init1: 361 opt: 615 Z-score: 546.2 bits: 109.9 E(85289): 1.1e-23
Smith-Waterman score: 615; 31.3% identity (64.3% similar) in 367 aa overlap (22-382:27-386)
10 20 30 40 50
pF1KB8 MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGT-FAQSKCPQVEWLG
:. :...... :.. : .: :. ::.. .
NP_114 MKKMNHKSTDSPKAPQLRGGVFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 WLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWA
.. .. : . ..::.. . : .:. :. .. . ::: ..: ::: ::: . ::.::
NP_114 YIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 ITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWA
. . .. : ::. ::....: .:.:::.:. .: .:::::::.:. :. : . :
NP_114 VYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 KLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSL--IWEVFTNMLLNVVG
:. ..:: . : : : .. :.. . :. :.:.:.. : : . .. :..:
NP_114 KVTCIIIWLLAGLASLPAIIHRNV--FFIENTNITVCAFHYESQNSTLPIGLGLTKNILG
190 200 210 220 230
240 250 260 270 280 290
pF1KB8 FLLPLSVITFCTMQIMQVLRNN-EMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTF
::.:. .: : ..:.. :.:: : . . ......:.:.. :.: :: ::
NP_114 FLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDD--IFKIIMAIVLFFFFSWIPHQIFTF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 LDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVC
::.: .:::. .:. :.:. :. .:: :.::::: : ..::.:.. .. . .
NP_114 LDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIP
300 310 320 330 340 350
360 370 380 390
pF1KB8 QKGGCRSEPIQMENSMGTL--RTSISVERQIHKLQDWAGSRQ
:. .:. . ..:.:: : : .: . .:
NP_114 PKAKSHSN---LSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
360 370 380 390
>>NP_004826 (OMIM: 106165,145500,267430) type-1 angioten (394 aa)
initn: 519 init1: 361 opt: 615 Z-score: 546.2 bits: 109.9 E(85289): 1.1e-23
Smith-Waterman score: 615; 31.3% identity (64.3% similar) in 367 aa overlap (22-382:27-386)
10 20 30 40 50
pF1KB8 MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGT-FAQSKCPQVEWLG
:. :...... :.. : .: :. ::.. .
NP_004 MKKMNHKSTDSPKAPQLRGGVFDIVFATNSTQVIKMILNSSTEDGIKRIQDDCPKAGRHN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 WLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWA
.. .. : . ..::.. . : .:. :. .. . ::: ..: ::: ::: . ::.::
NP_004 YIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 ITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWA
. . .. : ::. ::....: .:.:::.:. .: .:::::::.:. :. : . :
NP_004 VYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 KLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSL--IWEVFTNMLLNVVG
:. ..:: . : : : .. :.. . :. :.:.:.. : : . .. :..:
NP_004 KVTCIIIWLLAGLASLPAIIHRNV--FFIENTNITVCAFHYESQNSTLPIGLGLTKNILG
190 200 210 220 230
240 250 260 270 280 290
pF1KB8 FLLPLSVITFCTMQIMQVLRNN-EMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTF
::.:. .: : ..:.. :.:: : . . ......:.:.. :.: :: ::
NP_004 FLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDD--IFKIIMAIVLFFFFSWIPHQIFTF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 LDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVC
::.: .:::. .:. :.:. :. .:: :.::::: : ..::.:.. .. . .
NP_004 LDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIP
300 310 320 330 340 350
360 370 380 390
pF1KB8 QKGGCRSEPIQMENSMGTL--RTSISVERQIHKLQDWAGSRQ
:. .:. . ..:.:: : : .: . .:
NP_004 PKAKSHSN---LSTKMSTLSYRPSDNVSSSTKKPAPCFEVE
360 370 380 390
>>NP_005192 (OMIM: 601834) C-C chemokine receptor type 8 (355 aa)
initn: 564 init1: 203 opt: 611 Z-score: 543.2 bits: 109.2 E(85289): 1.6e-23
Smith-Waterman score: 611; 31.3% identity (69.7% similar) in 294 aa overlap (63-353:41-321)
40 50 60 70 80 90
pF1KB8 LQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVA
: .:::.. : : .:. :. . :. ...
NP_005 TVTDYYYPDIFSSPCDAELIQTNGKLLLAVFYCLLFVFSLLGNSLVILVLVVCKKLRSIT
20 30 40 50 60 70
100 110 120 130 140 150
pF1KB8 EIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVS
..:: ::: .::... ..:: . . .. :.:: ..:.::... ...:::. :. :.:
NP_005 DVYLLNLALSDLLFVFSFPFQTYYLLDQ--WVFGTVMCKVVSGFYYIGFYSSMFFITLMS
80 90 100 110 120
160 170 180 190 200 210
pF1KB8 IDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACV
.:::::.:... ..: .: . :..: ... . :.::: . :..: : :
NP_005 VDRYLAVVHAVYALKVRTIRMGTTLCLAVWLTAIMATIPLLVFYQVA--SEDG--VLQCY
130 140 150 160 170 180
220 230 240 250 260
pF1KB8 ISY--PSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIM-QVLRNNEMQKFKEIQTERRAT
: .: :..:::. .:..:.:.:.... :: ..:. :. : .. .: : :.
NP_005 SFYNQQTLKWKIFTNFKMNILGLLIPFTIFMFCYIKILHQLKRCQNHNKTKAIR------
190 200 210 220 230
270 280 290 300 310 320
pF1KB8 VLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNP
:::.:.. .. :.::.. :: .:: . ::..:. . . :... ...... :.::
NP_005 -LVLIVVIASLLFWVPFNVVLFLTSLHSMHILDGCSISQQLTYATHVTEIISFTHCCVNP
240 250 260 270 280 290
330 340 350 360 370 380
pF1KB8 LVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTLRTSISVERQIHKLQDWAGS
..:..::..:.:. :..: :..
NP_005 VIYAFVGEKFKKHLSEIFQKSCSQIFNYLGRQMPRESCEKSSSCQQHSSRSSSVDYIL
300 310 320 330 340 350
>>NP_000676 (OMIM: 106165,145500,267430) type-1 angioten (359 aa)
initn: 519 init1: 361 opt: 605 Z-score: 538.0 bits: 108.2 E(85289): 3.1e-23
Smith-Waterman score: 605; 31.6% identity (64.0% similar) in 342 aa overlap (44-382:15-351)
20 30 40 50 60 70
pF1KB8 REDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATL
:. ::.. ... .. : . ..::.. .
NP_000 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIF
10 20 30 40
80 90 100 110 120 130
pF1KB8 ENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVV
: .:. :. .. . ::: ..: ::: ::: . ::.::. . .. : ::. ::...
NP_000 GNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIA
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB8 NAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPML
.: .:.:::.:. .: .:::::::.:. :. : . ::. ..:: . : : : .
NP_000 SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB8 VFRTMKEYSDEGHNVTACVISYPSL--IWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVL
. :.. . :. :.:.:.. : : . .. :..:::.:. .: : ..:
NP_000 IHRNV--FFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKAL
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB8 RNN-EMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERII
.. :.:: : . . ......:.:.. :.: :: ::::.: .:::. .:. :.
NP_000 KKAYEIQKNKPRNDD--IFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIV
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB8 DVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTL
:. :. .:: :.::::: : ..::.:.. .. . . :. .:. .. . : .
NP_000 DTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSN-LSTKMSTLSY
290 300 310 320 330
380 390
pF1KB8 RTSISVERQIHKLQDWAGSRQ
: : .: . .:
NP_000 RPSDNVSSSTKKPAPCFEVE
340 350
>>NP_033611 (OMIM: 106165,145500,267430) type-1 angioten (359 aa)
initn: 519 init1: 361 opt: 605 Z-score: 538.0 bits: 108.2 E(85289): 3.1e-23
Smith-Waterman score: 605; 31.6% identity (64.0% similar) in 342 aa overlap (44-382:15-351)
20 30 40 50 60 70
pF1KB8 REDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATL
:. ::.. ... .. : . ..::.. .
NP_033 MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIF
10 20 30 40
80 90 100 110 120 130
pF1KB8 ENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVV
: .:. :. .. . ::: ..: ::: ::: . ::.::. . .. : ::. ::...
NP_033 GNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIA
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB8 NAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPML
.: .:.:::.:. .: .:::::::.:. :. : . ::. ..:: . : : : .
NP_033 SASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB8 VFRTMKEYSDEGHNVTACVISYPSL--IWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVL
. :.. . :. :.:.:.. : : . .. :..:::.:. .: : ..:
NP_033 IHRNV--FFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKAL
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB8 RNN-EMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERII
.. :.:: : . . ......:.:.. :.: :: ::::.: .:::. .:. :.
NP_033 KKAYEIQKNKPRNDD--IFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIV
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB8 DVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTL
:. :. .:: :.::::: : ..::.:.. .. . . :. .:. .. . : .
NP_033 DTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSN-LSTKMSTLSY
290 300 310 320 330
380 390
pF1KB8 RTSISVERQIHKLQDWAGSRQ
: : .: . .:
NP_033 RPSDNVSSSTKKPAPCFEVE
340 350
391 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:53:10 2016 done: Fri Nov 4 16:53:11 2016
Total Scan time: 6.770 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]