FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB8996, 407 aa 1>>>pF1KB8996 407 - 407 aa - 407 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6919+/-0.000857; mu= 5.3431+/- 0.052 mean_var=244.1589+/-49.616, 0's: 0 Z-trim(116.2): 32 B-trim: 430 in 1/53 Lambda= 0.082080 statistics sampled from 16746 (16778) to 16746 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.515), width: 16 Scan time: 2.930 The best scores are: opt bits E(32554) CCDS2132.1 INHBB gene_id:3625|Hs108|chr2 ( 407) 2859 350.9 1.3e-96 CCDS5464.1 INHBA gene_id:3624|Hs108|chr7 ( 426) 700 95.2 1.2e-19 CCDS8938.1 INHBC gene_id:3626|Hs108|chr12 ( 352) 623 86.0 5.9e-17 CCDS8939.1 INHBE gene_id:83729|Hs108|chr12 ( 350) 552 77.6 2e-14 >>CCDS2132.1 INHBB gene_id:3625|Hs108|chr2 (407 aa) initn: 2859 init1: 2859 opt: 2859 Z-score: 1848.0 bits: 350.9 E(32554): 1.3e-96 Smith-Waterman score: 2859; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407) 10 20 30 40 50 60 pF1KB8 MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB8 FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 FRRPEELGRVDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB8 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 VEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB8 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 YLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB8 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 RGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB8 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 NLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRM 310 320 330 340 350 360 370 380 390 400 pF1KB8 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA ::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 RGLNPGTVNSCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA 370 380 390 400 >>CCDS5464.1 INHBA gene_id:3624|Hs108|chr7 (426 aa) initn: 1151 init1: 437 opt: 700 Z-score: 466.1 bits: 95.2 E(32554): 1.2e-19 Smith-Waterman score: 1131; 43.3% identity (69.7% similar) in 413 aa overlap (43-407:22-426) 20 30 40 50 60 70 pF1KB8 CLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQ-DTCTSCGGFRRPEELGRVD : ::: : : : ::. :... . CCDS54 MPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQ 10 20 30 40 50 80 90 100 110 120 130 pF1KB8 GDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHAS ...::::.:::. :... ::..:. :::::...:.::::.::: :.: ::: :. . CCDS54 PEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYVEIEDDIGRRA 60 70 80 90 100 110 140 150 160 170 180 190 pF1KB8 PGADGQERVSEIISFAETDGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKLLPYVLEK . .:..::::.:::. ...: :.: ::.::.. : .: .::.::. : : CCDS54 EMNELMEQTSEIITFAES---GTARKTLHFEISKEGSDLSVVERAEVWLFLKV-P----K 120 130 140 150 160 200 210 220 230 pF1KB8 GSRRKVRVKVY-FQEQGH-----------------GDRWNMV--EKRVDLKRSGWHTFPL ..: ...: . ::.: : :.: ... :: :: ..: ::.::. CCDS54 ANRTRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGERSELLLSEKVVDARKSTWHVFPV 170 180 190 200 210 220 240 250 260 pF1KB8 TEAIQALFERGERRLNLDVQCDSCQELAVVPVFV-------DPGE--------------- . .:: :...:. :.. . :..::: .. :.. . :: CCDS54 SSSIQRLLDQGKSSLDVRIACEQCQESGASLVLLGKKKKKEEEGEGKKKGGGEGGAGADE 230 240 250 260 270 280 270 280 290 300 310 320 pF1KB8 ---ESHRPFVVVQARLG-DSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPT .:::::...::: . : :: :.:::::::..:.::..:::..:. ::::::::::. CCDS54 EKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSFKDIGWNDWIIAPS 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB8 GYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNP-GTVNSCCIPTKLSTMSMLY ::..::::: ::...::. ::. :::..:.:.::::: .: ....:::.:::: ::::: CCDS54 GYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLY 350 360 370 380 390 400 390 400 pF1KB8 FDDEYNIVKRDVPNMIVEECGCA .:: ::.:.:. :::::::::. CCDS54 YDDGQNIIKKDIQNMIVEECGCS 410 420 >>CCDS8938.1 INHBC gene_id:3626|Hs108|chr12 (352 aa) initn: 709 init1: 338 opt: 623 Z-score: 417.8 bits: 86.0 E(32554): 5.9e-17 Smith-Waterman score: 776; 38.3% identity (64.6% similar) in 373 aa overlap (42-407:14-352) 20 30 40 50 60 pF1KB8 ACLLLLAAGWLGPEAWGSPTPPPTPAAPPPPPPPGSP-GGSQDTCTSCGGFRRPE-ELGR : ..: .:.: : .::: : :: CCDS89 MTSSLLLAFLLLAPTTVATPRAGGQ--CPACGG---PTLELES 10 20 30 70 80 90 100 110 120 pF1KB8 VDGDFLEAVKRHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGH .:. .:: ::..:.. ::.... : .::. :::..::. .:. CCDS89 QRELLLDLAKRSILDKLHLTQRPTLNRPVSRAALRTALQHLHG----------VPQ---- 40 50 60 70 80 130 140 150 160 170 180 pF1KB8 ASPGADGQERVSEIISFAETDGLAS-SRVRLYF-FISNEGNQNLFVVQASLWLYLKLLPY .. :..:. :::::::: ::.. ...:: : : :.. . : :::: ....: : CCDS89 GALLEDNREQECEIISFAET-GLSTINQTRLDFHFSSDRTAGDREVQQASLMFFVQL-PS 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB8 VLEKGSRRKVRVKVYFQEQGHGDRWNMVEKRV-DLKRSGWHTFPLTEAIQALFERGERRL . :::: : :. ... . . .. :::: .:: :: .:. : CCDS89 --NTTWTLKVRVLVL---GPHNTNLTLATQYLLEVDASGWHQLPLGPEAQAACSQGHLTL 150 160 170 180 190 250 260 270 280 290 300 pF1KB8 NLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQ .: .. . : ... : .:::::....:.: ..:.:..::..:.: . .:::: CCDS89 ELVLEGQVAQSSVIL------GGAAHRPFVAARVRVG-GKHQIHRRGIDCQGGSRMCCRQ 200 210 220 230 240 250 310 320 330 340 350 360 pF1KB8 QFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPG .::.::: :::.:::: : :: :.: :.:: ..::.:: :.::::::.: . . : CCDS89 EFFVDFREIGWHDWIIQPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKA-NTAAG 260 270 280 290 300 370 380 390 400 pF1KB8 TVN--SCCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA :.. :::.:: .:.::.: . :::: :.:.:.:: :::. CCDS89 TTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPDMVVEACGCS 310 320 330 340 350 >>CCDS8939.1 INHBE gene_id:83729|Hs108|chr12 (350 aa) initn: 627 init1: 278 opt: 552 Z-score: 372.4 bits: 77.6 E(32554): 2e-14 Smith-Waterman score: 668; 36.2% identity (59.9% similar) in 367 aa overlap (50-407:21-350) 20 30 40 50 60 70 pF1KB8 GWLGPEAWGSPTPPPTPAAPPPPPPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFLEAVK :. ..: :::: . . :. :: .: CCDS89 MRLPDVQLWLVLLWALVRAQGTGSVCPSCGGSKLAPQAERAL--VLELAK 10 20 30 40 80 90 100 110 120 130 pF1KB8 RHILSRLQMRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQER ..::. :.. .:: ::: :.::.. :::.:. :.: .:: .:.: CCDS89 QQILDGLHLTSRPRITHPPPQAALTRALRRLQPGSV---------------APG-NGEE- 50 60 70 80 90 140 150 160 170 180 190 pF1KB8 VSEIISFAE-TDGLASSRVRLYFFISNEGNQNLFVVQASLWLY-LKLLPYVLEKGSRRKV .:::: ::. .. : : .:. ...:. .: :::. : :: .: : CCDS89 ---VISFATVTDSTSAYSSLLTFHLSTPRSHHLY--HARLWLHVLPTLPGTL---CLRIF 100 110 120 130 140 200 210 220 230 240 250 pF1KB8 RVKVYFQEQGHGDRWNMVEKRVDLKRSGWHTFPLTEAIQALFERGERRLNLDVQCDSCQE : ..:: .: ..:... ::::. : . .: :::. : .: : :. CCDS89 RWGPRRRRQG--SRTLLAEHHIT--NLGWHTLTLPSS--GL--RGEKSGVLKLQLD-CRP 150 160 170 180 190 260 270 280 290 300 310 pF1KB8 L-AVVPVFVDP----GEESHR-PFVVVQARLGD-SRHRIRKRGLECDGRTNLCCRQQFFI : . : .: .:. ::. .. : .. . : :.: :. : ::::.. .. CCDS89 LEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYV 200 210 220 230 240 250 320 330 340 350 360 370 pF1KB8 DFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGTVNS ::. .:: :::. : :: ::: :.:: .::: :: :.:::.:: . . . :... : CCDS89 DFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAST-S 260 270 280 290 300 310 380 390 400 pF1KB8 CCIPTKLSTMSMLYFDDEYNIVKRDVPNMIVEECGCA ::.:: .:.::.: . :.:: :::.:.:: :::. CCDS89 CCVPTARRPLSLLYLDHNGNVVKTDVPDMVVEACGCS 320 330 340 350 407 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:52:21 2016 done: Sat Nov 5 00:52:22 2016 Total Scan time: 2.930 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]