FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9017, 443 aa 1>>>pF1KB9017 443 - 443 aa - 443 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3084+/-0.000808; mu= 13.3582+/- 0.049 mean_var=94.2412+/-19.931, 0's: 0 Z-trim(109.6): 9 B-trim: 138 in 1/51 Lambda= 0.132116 statistics sampled from 10975 (10984) to 10975 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.337), width: 16 Scan time: 2.890 The best scores are: opt bits E(32554) CCDS11319.1 TADA2A gene_id:6871|Hs108|chr17 ( 443) 3023 586.3 2e-167 CCDS45656.1 TADA2A gene_id:6871|Hs108|chr17 ( 305) 1926 377.1 1.3e-104 CCDS47007.1 TADA2B gene_id:93624|Hs108|chr4 ( 420) 512 107.7 2.3e-23 >>CCDS11319.1 TADA2A gene_id:6871|Hs108|chr17 (443 aa) initn: 3023 init1: 3023 opt: 3023 Z-score: 3119.1 bits: 586.3 E(32554): 2e-167 Smith-Waterman score: 3023; 100.0% identity (100.0% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB9 MDRLGSFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MDRLGSFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 YEIMTSDFPVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 YEIMTSDFPVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFIN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NYAEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQLME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 NYAEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQLME 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RTYDHLKKTREEERLKRTMLSEVLQYIQDSSACQQWLRRQADIDSGLSPSIPMASNSGRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 RTYDHLKKTREEERLKRTMLSEVLQYIQDSSACQQWLRRQADIDSGLSPSIPMASNSGRR 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SAPPLNLTGLPGTEKLNEKEKELCQMVRLVPGAYLEYKSALLNECNKQGGLRLAQARALI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 SAPPLNLTGLPGTEKLNEKEKELCQMVRLVPGAYLEYKSALLNECNKQGGLRLAQARALI 370 380 390 400 410 420 430 440 pF1KB9 KIDVNKTRKIYDFLIREGYITKG ::::::::::::::::::::::: CCDS11 KIDVNKTRKIYDFLIREGYITKG 430 440 >>CCDS45656.1 TADA2A gene_id:6871|Hs108|chr17 (305 aa) initn: 1926 init1: 1926 opt: 1926 Z-score: 1991.5 bits: 377.1 E(32554): 1.3e-104 Smith-Waterman score: 1926; 97.9% identity (98.6% similar) in 282 aa overlap (1-282:1-282) 10 20 30 40 50 60 pF1KB9 MDRLGSFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MDRLGSFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 YEIMTSDFPVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 YEIMTSDFPVLDPSWTAQEEMALLEAVMDCGFGNWQDVANQMCTKTKEECEKHYMKHFIN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 NPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NPLFASTLLNLKQAEEAKTADTAIPFHSTDDPPRPTFDSLLSRDMAGYMPARADFIEEFD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 NYAEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQLME :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 NYAEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLINLRKFQLME 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKRLQEYRTAGITNFCSA :::::::::::::::::::::::::::::::::: .. : : CCDS45 RRYPKEVQDLYETMRRFARIVGPVEHDKFIESHACRWFLSLEQYLCVYIYINRRDNGVFY 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RTYDHLKKTREEERLKRTMLSEVLQYIQDSSACQQWLRRQADIDSGLSPSIPMASNSGRR CCDS45 VKFYK >>CCDS47007.1 TADA2B gene_id:93624|Hs108|chr4 (420 aa) initn: 571 init1: 189 opt: 512 Z-score: 532.9 bits: 107.7 E(32554): 2.3e-23 Smith-Waterman score: 557; 27.9% identity (57.1% similar) in 445 aa overlap (14-442:6-417) 10 20 30 40 50 60 pF1KB9 MDRLGSFSNDPSDKPPCRGCSSYLMEPYIKCAECGPPPFFLCLQCFTRGFEYKKHQSDHT : : : . . ..:.:: . :: .::. : : .:. : CCDS47 MAELGKKYCVYCLAEVSPLRFRCTEC--QDIELCPECFSAGAEIGHHRRYHG 10 20 30 40 50 70 80 90 100 110 pF1KB9 YEIMTSD-FPVLDP----SWTAQEEMALLEAVMDCGFGNWQDVANQM-CTKTKEECEKHY :... . : . : .::..::. ::.:. . :::::.:.: .. ..: .: .:: CCDS47 YQLVDGGRFTLWGPEAEGGWTSREEQLLLDAIEQFGFGNWEDMAAHVGASRTPQEVMEHY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 MKHFINNPLFASTLLN-LKQAEEAKTADTAIPFHSTDDPPRPTFD-SLLSRDMAGYMPAR .. .:.. : . . . . . .: .. :. . : : .: :. ... :::: : CCDS47 VSMYIHGNLGKACIPDTIPNRVTDHTCPSGGPLSPSLTTPLPPLDISVAEQQQLGYMPLR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 ADFIEEFDNYAEWDLRDIDFVEDDSDILHALKMAVVDIYHSRLKERQRRKKIIRDHGLI- :. :.:. :: . .. ::.:. :: : ::.: .::::::::.: ::..:. CCDS47 DDYEIEYDQDAETLISGLSVNYDDDDVEIELKRAHVDMYVRKLKERQRRKNIARDYNLVP 180 190 200 210 220 230 240 250 260 270 280 pF1KB9 ------NLRKFQLMERRYPKEVQDLYETMRRFARIVGPVEHDKFIESHALEFELRREIKR . .: . ..:. :: ..: .: . .... : : ..:. : :: .:.. CCDS47 AFLGKDKKEKEKALKRKITKEEKELRLKLRPLYQFMSCKEFDDLFENMHKEKMLRAKIRE 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB9 LQEYRTAGITNFCSARTYDHLKKTREEERLKRTMLSEVLQYIQDSSACQQWLRRQADIDS ::.:: :::.. . :. .. ::... .... : .. : . : CCDS47 LQRYRRNGITKMEESAEYEAARHKREKRKENKNL------------AGSK--RGKED--- 300 310 320 330 350 360 370 380 390 400 pF1KB9 GLSPSIPMASNSGRRSAPPLNLTGLPGTEKLNEKEKELCQMVRLVPGAYLEYKSALLNE- :. : . .::: : :...:: ::. . : :. :. :. .... CCDS47 ------------GKDSEFA-AIENLPGFELLSDREKVLCSSLNLSPARYVTVKTIIIKDH 340 350 360 370 380 410 420 430 440 pF1KB9 CNKQGGLRLAQARALIKIDVNKTRKIYDFLIREGYITKG .:. :. ...: .: ..: .:: . :.:.. CCDS47 LQKRQGIP-SKSRLPSYLDKVLKKRILNFLTESGWISRDAS 390 400 410 420 443 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:17:07 2016 done: Thu Nov 3 18:17:07 2016 Total Scan time: 2.890 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]