FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9019, 2458 aa 1>>>pF1KB9019 2458 - 2458 aa - 2458 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.2844+/-0.000599; mu= 12.1696+/- 0.037 mean_var=186.7076+/-39.194, 0's: 0 Z-trim(111.3): 108 B-trim: 550 in 2/54 Lambda= 0.093863 statistics sampled from 19791 (19899) to 19791 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.559), E-opt: 0.2 (0.233), width: 16 Scan time: 19.030 The best scores are: opt bits E(85289) XP_011536561 (OMIM: 601557) PREDICTED: acetyl-CoA (2458) 16363 2230.9 0 NP_001084 (OMIM: 601557) acetyl-CoA carboxylase 2 (2458) 16363 2230.9 0 XP_005253933 (OMIM: 601557) PREDICTED: acetyl-CoA (2458) 16363 2230.9 0 XP_011536566 (OMIM: 601557) PREDICTED: acetyl-CoA (2249) 14925 2036.1 0 XP_006719430 (OMIM: 601557) PREDICTED: acetyl-CoA (2256) 14922 2035.7 0 XP_016874741 (OMIM: 601557) PREDICTED: acetyl-CoA (2193) 9185 1258.8 0 XP_011536565 (OMIM: 601557) PREDICTED: acetyl-CoA (2395) 9185 1258.8 0 XP_011536567 (OMIM: 601557) PREDICTED: acetyl-CoA (1304) 8585 1177.4 0 XP_006721916 (OMIM: 200350,613933) PREDICTED: acet (2375) 6487 893.5 0 XP_016880043 (OMIM: 200350,613933) PREDICTED: acet (2383) 6471 891.3 0 XP_011523005 (OMIM: 200350,613933) PREDICTED: acet (2346) 6072 837.3 0 NP_942136 (OMIM: 200350,613933) acetyl-CoA carboxy (2346) 6072 837.3 0 XP_016880044 (OMIM: 200350,613933) PREDICTED: acet (2346) 6072 837.3 0 NP_942133 (OMIM: 200350,613933) acetyl-CoA carboxy (2346) 6072 837.3 0 NP_942131 (OMIM: 200350,613933) acetyl-CoA carboxy (2383) 6072 837.3 0 XP_011523003 (OMIM: 200350,613933) PREDICTED: acet (2353) 6058 835.4 0 XP_016880042 (OMIM: 200350,613933) PREDICTED: acet (2391) 6056 835.1 0 NP_942134 (OMIM: 200350,613933) acetyl-CoA carboxy (2288) 6048 834.0 0 XP_005257324 (OMIM: 200350,613933) PREDICTED: acet (2268) 6037 832.5 0 NP_942135 (OMIM: 200350,613933) acetyl-CoA carboxy (2268) 6037 832.5 0 XP_011523006 (OMIM: 200350,613933) PREDICTED: acet (2268) 6037 832.5 0 XP_016876098 (OMIM: 232000,606054) PREDICTED: prop ( 695) 601 96.0 1.8e-18 NP_001121164 (OMIM: 232000,606054) propionyl-CoA c ( 702) 601 96.0 1.8e-18 NP_000273 (OMIM: 232000,606054) propionyl-CoA carb ( 728) 601 96.0 1.9e-18 XP_011511295 (OMIM: 210200,609010) PREDICTED: meth ( 472) 540 87.6 4.1e-16 XP_016876105 (OMIM: 232000,606054) PREDICTED: prop ( 551) 541 87.8 4.2e-16 XP_016876104 (OMIM: 232000,606054) PREDICTED: prop ( 624) 541 87.9 4.6e-16 XP_005254116 (OMIM: 232000,606054) PREDICTED: prop ( 640) 541 87.9 4.7e-16 XP_016876103 (OMIM: 232000,606054) PREDICTED: prop ( 655) 541 87.9 4.8e-16 XP_016876102 (OMIM: 232000,606054) PREDICTED: prop ( 669) 541 87.9 4.9e-16 XP_016876101 (OMIM: 232000,606054) PREDICTED: prop ( 681) 541 87.9 4.9e-16 NP_001171475 (OMIM: 232000,606054) propionyl-CoA c ( 681) 541 87.9 4.9e-16 XP_016876100 (OMIM: 232000,606054) PREDICTED: prop ( 683) 541 87.9 5e-16 NP_001280202 (OMIM: 210200,609010) methylcrotonoyl ( 608) 540 87.7 5e-16 XP_016876099 (OMIM: 232000,606054) PREDICTED: prop ( 689) 541 87.9 5e-16 XP_006713765 (OMIM: 210200,609010) PREDICTED: meth ( 616) 540 87.7 5e-16 XP_016862364 (OMIM: 210200,609010) PREDICTED: meth ( 616) 540 87.7 5e-16 XP_016862363 (OMIM: 210200,609010) PREDICTED: meth ( 616) 540 87.7 5e-16 XP_011519395 (OMIM: 232000,606054) PREDICTED: prop ( 699) 541 87.9 5e-16 XP_016876097 (OMIM: 232000,606054) PREDICTED: prop ( 710) 541 87.9 5.1e-16 XP_016876096 (OMIM: 232000,606054) PREDICTED: prop ( 711) 541 87.9 5.1e-16 XP_016876095 (OMIM: 232000,606054) PREDICTED: prop ( 718) 541 87.9 5.1e-16 XP_016876094 (OMIM: 232000,606054) PREDICTED: prop ( 744) 541 87.9 5.3e-16 XP_011511294 (OMIM: 210200,609010) PREDICTED: meth ( 687) 540 87.8 5.5e-16 NP_064551 (OMIM: 210200,609010) methylcrotonoyl-Co ( 725) 540 87.8 5.7e-16 XP_005274088 (OMIM: 266150,608786) PREDICTED: pyru (1178) 504 83.1 2.4e-14 XP_016873360 (OMIM: 266150,608786) PREDICTED: pyru (1178) 504 83.1 2.4e-14 XP_016873359 (OMIM: 266150,608786) PREDICTED: pyru (1178) 504 83.1 2.4e-14 NP_000911 (OMIM: 266150,608786) pyruvate carboxyla (1178) 504 83.1 2.4e-14 XP_006718641 (OMIM: 266150,608786) PREDICTED: pyru (1178) 504 83.1 2.4e-14 >>XP_011536561 (OMIM: 601557) PREDICTED: acetyl-CoA carb (2458 aa) initn: 16363 init1: 16363 opt: 16363 Z-score: 11980.3 bits: 2230.9 E(85289): 0 Smith-Waterman score: 16363; 100.0% identity (100.0% similar) in 2458 aa overlap (1-2458:1-2458) 10 20 30 40 50 60 pF1KB9 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB9 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB9 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB9 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KB9 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KB9 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KB9 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KB9 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 pF1KB9 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2410 2420 2430 2440 2450 >>NP_001084 (OMIM: 601557) acetyl-CoA carboxylase 2 prec (2458 aa) initn: 16363 init1: 16363 opt: 16363 Z-score: 11980.3 bits: 2230.9 E(85289): 0 Smith-Waterman score: 16363; 100.0% identity (100.0% similar) in 2458 aa overlap (1-2458:1-2458) 10 20 30 40 50 60 pF1KB9 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB9 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB9 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB9 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KB9 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KB9 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KB9 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KB9 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 pF1KB9 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2410 2420 2430 2440 2450 >>XP_005253933 (OMIM: 601557) PREDICTED: acetyl-CoA carb (2458 aa) initn: 16363 init1: 16363 opt: 16363 Z-score: 11980.3 bits: 2230.9 E(85289): 0 Smith-Waterman score: 16363; 100.0% identity (100.0% similar) in 2458 aa overlap (1-2458:1-2458) 10 20 30 40 50 60 pF1KB9 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL 1870 1880 1890 1900 1910 1920 1930 1940 1950 1960 1970 1980 pF1KB9 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL 1930 1940 1950 1960 1970 1980 1990 2000 2010 2020 2030 2040 pF1KB9 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR 1990 2000 2010 2020 2030 2040 2050 2060 2070 2080 2090 2100 pF1KB9 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE 2050 2060 2070 2080 2090 2100 2110 2120 2130 2140 2150 2160 pF1KB9 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF 2110 2120 2130 2140 2150 2160 2170 2180 2190 2200 2210 2220 pF1KB9 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA 2170 2180 2190 2200 2210 2220 2230 2240 2250 2260 2270 2280 pF1KB9 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK 2230 2240 2250 2260 2270 2280 2290 2300 2310 2320 2330 2340 pF1KB9 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK 2290 2300 2310 2320 2330 2340 2350 2360 2370 2380 2390 2400 pF1KB9 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR 2350 2360 2370 2380 2390 2400 2410 2420 2430 2440 2450 pF1KB9 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2410 2420 2430 2440 2450 >>XP_011536566 (OMIM: 601557) PREDICTED: acetyl-CoA carb (2249 aa) initn: 14925 init1: 14925 opt: 14925 Z-score: 10928.4 bits: 2036.1 E(85289): 0 Smith-Waterman score: 14925; 100.0% identity (100.0% similar) in 2241 aa overlap (218-2458:9-2249) 190 200 210 220 230 240 pF1KB9 TRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASP :::::::::::::::::::::::::::::: XP_011 MIPVSSLFRPSMSGLHLVKRGREHKKLDLHRDFTVASP 10 20 30 250 260 270 280 290 300 pF1KB9 AEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKAN 40 50 60 70 80 90 310 320 330 340 350 360 pF1KB9 AEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKN 100 110 120 130 140 150 370 380 390 400 410 420 pF1KB9 GVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPED 160 170 180 190 200 210 430 440 450 460 470 480 pF1KB9 VYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGS 220 230 240 250 260 270 490 500 510 520 530 540 pF1KB9 PIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFM 280 290 300 310 320 330 550 560 570 580 590 600 pF1KB9 EQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQI 340 350 360 370 380 390 610 620 630 640 650 660 pF1KB9 AMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSG 400 410 420 430 440 450 670 680 690 700 710 720 pF1KB9 TVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 460 470 480 490 500 510 730 740 750 760 770 780 pF1KB9 GDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMF 520 530 540 550 560 570 790 800 810 820 830 840 pF1KB9 RTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEI 580 590 600 610 620 630 850 860 870 880 890 900 pF1KB9 DAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQ 640 650 660 670 680 690 910 920 930 940 950 960 pF1KB9 YTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPS 700 710 720 730 740 750 970 980 990 1000 1010 1020 pF1KB9 KVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQK 760 770 780 790 800 810 1030 1040 1050 1060 1070 1080 pF1KB9 LMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATI 820 830 840 850 860 870 1090 1100 1110 1120 1130 1140 pF1KB9 LDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQA 880 890 900 910 920 930 1150 1160 1170 1180 1190 1200 pF1KB9 HYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISILN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISILN 940 950 960 970 980 990 1210 1220 1230 1240 1250 1260 pF1KB9 ELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLI 1000 1010 1020 1030 1040 1050 1270 1280 1290 1300 1310 1320 pF1KB9 LSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFML 1060 1070 1080 1090 1100 1110 1330 1340 1350 1360 1370 1380 pF1KB9 PSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVIS 1120 1130 1140 1150 1160 1170 1390 1400 1410 1420 1430 1440 pF1KB9 CFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQ 1180 1190 1200 1210 1220 1230 1450 1460 1470 1480 1490 1500 pF1KB9 SKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMRN 1240 1250 1260 1270 1280 1290 1510 1520 1530 1540 1550 1560 pF1KB9 FDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGER 1300 1310 1320 1330 1340 1350 1570 1580 1590 1600 1610 1620 pF1KB9 LLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLRV 1360 1370 1380 1390 1400 1410 1630 1640 1650 1660 1670 1680 pF1KB9 LQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGPQ 1420 1430 1440 1450 1460 1470 1690 1700 1710 1720 1730 1740 pF1KB9 HGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPKDILTYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPKDILTYTE 1480 1490 1500 1510 1520 1530 1750 1760 1770 1780 1790 1800 pF1KB9 LVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGED 1540 1550 1560 1570 1580 1590 1810 1820 1830 1840 1850 1860 pF1KB9 LLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTPQ 1600 1610 1620 1630 1640 1650 1870 1880 1890 1900 1910 1920 pF1KB9 DYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIVT 1660 1670 1680 1690 1700 1710 1930 1940 1950 1960 1970 1980 pF1KB9 ISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMH 1720 1730 1740 1750 1760 1770 1990 2000 2010 2020 2030 2040 pF1KB9 YNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPYDPRW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPYDPRW 1780 1790 1800 1810 1820 1830 2050 2060 2070 2080 2090 2100 pF1KB9 MLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVA 1840 1850 1860 1870 1880 1890 2110 2120 2130 2140 2150 2160 pF1KB9 VPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGGMKDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGGMKDM 1900 1910 1920 1930 1940 1950 2170 2180 2190 2200 2210 2220 pF1KB9 YDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRGG 1960 1970 1980 1990 2000 2010 2230 2240 2250 2260 2270 2280 pF1KB9 VLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKAREDLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKAREDLLL 2020 2030 2040 2050 2060 2070 2290 2300 2310 2320 2330 2340 pF1KB9 PIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQAS 2080 2090 2100 2110 2120 2130 2350 2360 2370 2380 2390 2400 pF1KB9 GELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYLK 2140 2150 2160 2170 2180 2190 2410 2420 2430 2440 2450 pF1KB9 HDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2200 2210 2220 2230 2240 >>XP_006719430 (OMIM: 601557) PREDICTED: acetyl-CoA carb (2256 aa) initn: 14922 init1: 14922 opt: 14922 Z-score: 10926.2 bits: 2035.7 E(85289): 0 Smith-Waterman score: 14922; 99.9% identity (100.0% similar) in 2242 aa overlap (217-2458:15-2256) 190 200 210 220 230 240 pF1KB9 STRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVAS ..:::::::::::::::::::::::::::: XP_006 MSPAKCKICFPDREVKPSMSGLHLVKRGREHKKLDLHRDFTVAS 10 20 30 40 250 260 270 280 290 300 pF1KB9 PAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKA 50 60 70 80 90 100 310 320 330 340 350 360 pF1KB9 NAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCK 110 120 130 140 150 160 370 380 390 400 410 420 pF1KB9 NGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPE 170 180 190 200 210 220 430 440 450 460 470 480 pF1KB9 DVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPG 230 240 250 260 270 280 490 500 510 520 530 540 pF1KB9 SPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEF 290 300 310 320 330 340 550 560 570 580 590 600 pF1KB9 MEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQ 350 360 370 380 390 400 610 620 630 640 650 660 pF1KB9 IAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSS 410 420 430 440 450 460 670 680 690 700 710 720 pF1KB9 GTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSI 470 480 490 500 510 520 730 740 750 760 770 780 pF1KB9 RGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAM 530 540 550 560 570 580 790 800 810 820 830 840 pF1KB9 FRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIE 590 600 610 620 630 640 850 860 870 880 890 900 pF1KB9 IDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 IDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLT 650 660 670 680 690 700 910 920 930 940 950 960 pF1KB9 QYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDP 710 720 730 740 750 760 970 980 990 1000 1010 1020 pF1KB9 SKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQ 770 780 790 800 810 820 1030 1040 1050 1060 1070 1080 pF1KB9 KLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIAT 830 840 850 860 870 880 1090 1100 1110 1120 1130 1140 pF1KB9 ILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQ 890 900 910 920 930 940 1150 1160 1170 1180 1190 1200 pF1KB9 AHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISIL 950 960 970 980 990 1000 1210 1220 1230 1240 1250 1260 pF1KB9 NELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKL 1010 1020 1030 1040 1050 1060 1270 1280 1290 1300 1310 1320 pF1KB9 ILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFM 1070 1080 1090 1100 1110 1120 1330 1340 1350 1360 1370 1380 pF1KB9 LPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVI 1130 1140 1150 1160 1170 1180 1390 1400 1410 1420 1430 1440 pF1KB9 SCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFV 1190 1200 1210 1220 1230 1240 1450 1460 1470 1480 1490 1500 pF1KB9 QSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMR 1250 1260 1270 1280 1290 1300 1510 1520 1530 1540 1550 1560 pF1KB9 NFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGE 1310 1320 1330 1340 1350 1360 1570 1580 1590 1600 1610 1620 pF1KB9 RLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLR 1370 1380 1390 1400 1410 1420 1630 1640 1650 1660 1670 1680 pF1KB9 VLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGP 1430 1440 1450 1460 1470 1480 1690 1700 1710 1720 1730 1740 pF1KB9 QHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPKDILTYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPKDILTYT 1490 1500 1510 1520 1530 1540 1750 1760 1770 1780 1790 1800 pF1KB9 ELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGE 1550 1560 1570 1580 1590 1600 1810 1820 1830 1840 1850 1860 pF1KB9 DLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTP 1610 1620 1630 1640 1650 1660 1870 1880 1890 1900 1910 1920 pF1KB9 QDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIV 1670 1680 1690 1700 1710 1720 1930 1940 1950 1960 1970 1980 pF1KB9 TISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIM 1730 1740 1750 1760 1770 1780 1990 2000 2010 2020 2030 2040 pF1KB9 HYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPYDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPYDPR 1790 1800 1810 1820 1830 1840 2050 2060 2070 2080 2090 2100 pF1KB9 WMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 WMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEV 1850 1860 1870 1880 1890 1900 2110 2120 2130 2140 2150 2160 pF1KB9 AVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGGMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGGMKD 1910 1920 1930 1940 1950 1960 2170 2180 2190 2200 2210 2220 pF1KB9 MYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRG 1970 1980 1990 2000 2010 2020 2230 2240 2250 2260 2270 2280 pF1KB9 GVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKAREDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKAREDLL 2030 2040 2050 2060 2070 2080 2290 2300 2310 2320 2330 2340 pF1KB9 LPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQA 2090 2100 2110 2120 2130 2140 2350 2360 2370 2380 2390 2400 pF1KB9 SGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYL 2150 2160 2170 2180 2190 2200 2410 2420 2430 2440 2450 pF1KB9 KHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2210 2220 2230 2240 2250 >>XP_016874741 (OMIM: 601557) PREDICTED: acetyl-CoA carb (2193 aa) initn: 9168 init1: 9168 opt: 9185 Z-score: 6727.8 bits: 1258.8 E(85289): 0 Smith-Waterman score: 14377; 97.1% identity (97.2% similar) in 2242 aa overlap (217-2458:15-2193) 190 200 210 220 230 240 pF1KB9 STRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVAS ..:::::::::::::::::::::::::::: XP_016 MSPAKCKICFPDREVKPSMSGLHLVKRGREHKKLDLHRDFTVAS 10 20 30 40 250 260 270 280 290 300 pF1KB9 PAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKA 50 60 70 80 90 100 310 320 330 340 350 360 pF1KB9 NAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCK 110 120 130 140 150 160 370 380 390 400 410 420 pF1KB9 NGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPE 170 180 190 200 210 220 430 440 450 460 470 480 pF1KB9 DVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPG 230 240 250 260 270 280 490 500 510 520 530 540 pF1KB9 SPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEF 290 300 310 320 330 340 550 560 570 580 590 600 pF1KB9 MEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQ 350 360 370 380 390 400 610 620 630 640 650 660 pF1KB9 IAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSS 410 420 430 440 450 460 670 680 690 700 710 720 pF1KB9 GTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSI 470 480 490 500 510 520 730 740 750 760 770 780 pF1KB9 RGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAM 530 540 550 560 570 580 790 800 810 820 830 840 pF1KB9 FRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIE 590 600 610 620 630 640 850 860 870 880 890 900 pF1KB9 IDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLT 650 660 670 680 690 700 910 920 930 940 950 960 pF1KB9 QYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDP 710 720 730 740 750 760 970 980 990 1000 1010 1020 pF1KB9 SKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK------ 770 780 790 800 810 1030 1040 1050 1060 1070 1080 pF1KB9 KLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIAT ::: XP_016 ---------------------------------------------------------IAT 820 1090 1100 1110 1120 1130 1140 pF1KB9 ILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQ 830 840 850 860 870 880 1150 1160 1170 1180 1190 1200 pF1KB9 AHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISIL 890 900 910 920 930 940 1210 1220 1230 1240 1250 1260 pF1KB9 NELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKL 950 960 970 980 990 1000 1270 1280 1290 1300 1310 1320 pF1KB9 ILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFM 1010 1020 1030 1040 1050 1060 1330 1340 1350 1360 1370 1380 pF1KB9 LPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVI 1070 1080 1090 1100 1110 1120 1390 1400 1410 1420 1430 1440 pF1KB9 SCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFV 1130 1140 1150 1160 1170 1180 1450 1460 1470 1480 1490 1500 pF1KB9 QSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELNRMR 1190 1200 1210 1220 1230 1240 1510 1520 1530 1540 1550 1560 pF1KB9 NFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGE 1250 1260 1270 1280 1290 1300 1570 1580 1590 1600 1610 1620 pF1KB9 RLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGSRLWKLR 1310 1320 1330 1340 1350 1360 1630 1640 1650 1660 1670 1680 pF1KB9 VLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSFGNKQGP 1370 1380 1390 1400 1410 1420 1690 1700 1710 1720 1730 1740 pF1KB9 QHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPKDILTYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPKDILTYT 1430 1440 1450 1460 1470 1480 1750 1760 1770 1780 1790 1800 pF1KB9 ELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIGSFGPGE 1490 1500 1510 1520 1530 1540 1810 1820 1830 1840 1850 1860 pF1KB9 DLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFKYLYLTP 1550 1560 1570 1580 1590 1600 1870 1880 1890 1900 1910 1920 pF1KB9 QDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSLAYEEIV 1610 1620 1630 1640 1650 1660 1930 1940 1950 1960 1970 1980 pF1KB9 TISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIM 1670 1680 1690 1700 1710 1720 1990 2000 2010 2020 2030 2040 pF1KB9 HYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPYDPR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSRAPYDPR 1730 1740 1750 1760 1770 1780 2050 2060 2070 2080 2090 2100 pF1KB9 WMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEV 1790 1800 1810 1820 1830 1840 2110 2120 2130 2140 2150 2160 pF1KB9 AVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGGMKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGFSGGMKD 1850 1860 1870 1880 1890 1900 2170 2180 2190 2200 2210 2220 pF1KB9 MYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYADKESRG 1910 1920 1930 1940 1950 1960 2230 2240 2250 2260 2270 2280 pF1KB9 GVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKAREDLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLKAREDLL 1970 1980 1990 2000 2010 2020 2290 2300 2310 2320 2330 2340 pF1KB9 LPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVKQEILQA 2030 2040 2050 2060 2070 2080 2350 2360 2370 2380 2390 2400 pF1KB9 SGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIRENITYL 2090 2100 2110 2120 2130 2140 2410 2420 2430 2440 2450 pF1KB9 KHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2150 2160 2170 2180 2190 >>XP_011536565 (OMIM: 601557) PREDICTED: acetyl-CoA carb (2395 aa) initn: 9168 init1: 9168 opt: 9185 Z-score: 6727.3 bits: 1258.8 E(85289): 0 Smith-Waterman score: 15818; 97.4% identity (97.4% similar) in 2458 aa overlap (1-2458:1-2395) 10 20 30 40 50 60 pF1KB9 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP XP_011 ------------------------------------------------------------ 1090 1100 1110 1120 1130 1140 pF1KB9 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ---IATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV 1030 1040 1050 1060 1070 1150 1160 1170 1180 1190 1200 pF1KB9 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD 1080 1090 1100 1110 1120 1130 1210 1220 1230 1240 1250 1260 pF1KB9 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP 1140 1150 1160 1170 1180 1190 1270 1280 1290 1300 1310 1320 pF1KB9 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV 1200 1210 1220 1230 1240 1250 1330 1340 1350 1360 1370 1380 pF1KB9 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR 1260 1270 1280 1290 1300 1310 1390 1400 1410 1420 1430 1440 pF1KB9 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFDEVISCFANVPKDTPLFSEARTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVP 1320 1330 1340 1350 1360 1370 1450 1460 1470 1480 1490 1500 pF1KB9 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ILRTFVQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQL 1380 1390 1400 1410 1420 1430 1510 1520 1530 1540 1550 1560 pF1KB9 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASFEY 1440 1450 1460 1470 1480 1490 1570 1580 1590 1600 1610 1620 pF1KB9 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRYGS 1500 1510 1520 1530 1540 1550 1630 1640 1650 1660 1670 1680 pF1KB9 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFHSF 1560 1570 1580 1590 1600 1610 1690 1700 1710 1720 1730 1740 pF1KB9 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGSPDKYPK 1620 1630 1640 1650 1660 1670 1750 1760 1770 1780 1790 1800 pF1KB9 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIVIGNDITFRIG 1680 1690 1700 1710 1720 1730 1810 1820 1830 1840 1850 1860 pF1KB9 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWVDPEDPHKGFK 1740 1750 1760 1770 1780 1790 1870 1880 1890 1900 1910 1920 pF1KB9 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRGSGMIAGESSL 1800 1810 1820 1830 1840 1850 1930 1940 1950 1960 1970 1980 pF1KB9 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQL 1860 1870 1880 1890 1900 1910 1990 2000 2010 2020 2030 2040 pF1KB9 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPIDREIEFLPSR 1920 1930 1940 1950 1960 1970 2050 2060 2070 2080 2090 2100 pF1KB9 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVE 1980 1990 2000 2010 2020 2030 2110 2120 2130 2140 2150 2160 pF1KB9 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLPLMIFANWRGF 2040 2050 2060 2070 2080 2090 2170 2180 2190 2200 2210 2220 pF1KB9 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDATINPLCIEMYA 2100 2110 2120 2130 2140 2150 2230 2240 2250 2260 2270 2280 pF1KB9 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDKDRKDLEGRLK 2160 2170 2180 2190 2200 2210 2290 2300 2310 2320 2330 2340 pF1KB9 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRLRRLLLEDQVK 2220 2230 2240 2250 2260 2270 2350 2360 2370 2380 2390 2400 pF1KB9 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQAGDGPRSTIR 2280 2290 2300 2310 2320 2330 2410 2420 2430 2440 2450 pF1KB9 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLSTMDSPAST 2340 2350 2360 2370 2380 2390 >>XP_011536567 (OMIM: 601557) PREDICTED: acetyl-CoA carb (1304 aa) initn: 8585 init1: 8585 opt: 8585 Z-score: 6291.8 bits: 1177.4 E(85289): 0 Smith-Waterman score: 8585; 100.0% identity (100.0% similar) in 1294 aa overlap (1-1294:1-1294) 10 20 30 40 50 60 pF1KB9 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVLLLCLSCLIFSCLTFSWLKIWGKMTDSKPITKSKSEANLIPSQEPFPASDNSGETPQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGEGHTLPKTPSQAEPASHKGPKDAGRRRNSLPPSHQKPPRNPLSSSDAAPSPELQANGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GTQGLEATDTNGLSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDSV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AGSSRESTRKGSRASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DFTVASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PEDLKANAEYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PELLCKNGVAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGK 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RISVPEDVYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQV 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QSEIPGSPIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAIFEFMEQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PAAQLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDE 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GFKPSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVA 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKELSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGAL 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NVADAMFRTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIM 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGCHIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSP 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SAGKLTQYTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVAR 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LELDDPSKVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIK 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKEWVQKLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFP 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SQQIATILDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRV 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EHHFQQAHYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSD 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELISILNELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCP 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCV :::::::::::::::::::::::::::::::::: XP_011 ENLKKLILSETTIFDVLPTFFYHANKVVCMASLEDDRAHQHHQP 1270 1280 1290 1300 1330 1340 1350 1360 1370 1380 pF1KB9 VEFQFMLPSSHPNRMTVPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTR >>XP_006721916 (OMIM: 200350,613933) PREDICTED: acetyl-C (2375 aa) initn: 11643 init1: 4844 opt: 6487 Z-score: 4752.8 bits: 893.5 E(85289): 0 Smith-Waterman score: 11843; 75.4% identity (90.6% similar) in 2326 aa overlap (163-2457:54-2375) 140 150 160 170 180 190 pF1KB9 LSSSARPQGQQAGSPSKEDKKQANIKRQLMTNFILGSF-DDYSSDEDS-VAGSSRESTRK . ::.:: .: : :: : .. . .. XP_006 VRIIRAVRAHFGGIMDEPSPLAQPLELNQHSRFIIGSVSEDNSEDEISNLVKLDLLEEKE 30 40 50 60 70 80 200 210 220 230 240 pF1KB9 GSR--ASLGALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPA :: ::.:. .: .. . . .: :::::::::.::..::.: .::::::::: XP_006 GSLSPASVGSDTLSDLGISSLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPA 90 100 110 120 130 140 250 260 270 280 290 300 pF1KB9 EFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANA ::::::::..::::::::::::::::::::::::.::::::::::::::::::::::::: XP_006 EFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANA 150 160 170 180 190 200 310 320 330 340 350 360 pF1KB9 EYIKMADHYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNG :::::::::::::::::::::::::::.:::::::::::::::::::::::::::: ::: XP_006 EYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNG 210 220 230 240 250 260 370 380 390 400 410 420 pF1KB9 VAFLGPPSEAMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRI-SVPED .::.::::.:::::::::::..:::: .:::::::::: :.: :.:. .::: .::.. XP_006 IAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDF--SKRILNVPQE 270 280 290 300 310 320 430 440 450 460 470 480 pF1KB9 VYDKGCVKDVDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGS .:.:: :::::.::.:::..:.:.:::::::::::::::...:.::: ::::::.:.::: XP_006 LYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGS 330 340 350 360 370 380 490 500 510 520 530 540 pF1KB9 PIFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFM :::.:.::...:::::::::::::::.::::::::.:::::::.:::::::: :.:: : XP_006 PIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHM 390 400 410 420 430 440 550 560 570 580 590 600 pF1KB9 EQCAIRLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQI ::::..::: :::::::::::::::::::.:::::::::::::::::.:::::::::::: XP_006 EQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQI 450 460 470 480 490 500 610 620 630 640 650 660 pF1KB9 AMGVPLHRLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSG :::.::.:.::::..:: :::: .::.:: .. : ::::::::::::::::::::::: XP_006 AMGIPLYRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSG 510 520 530 540 550 560 670 680 690 700 710 720 pF1KB9 TVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR :::::::::.:::::::::::.:::::::::::::::::::::::::::::::::::::: XP_006 TVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 570 580 590 600 610 620 730 740 750 760 770 780 pF1KB9 GDFRTTVEYLINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMF :::::::::::.:::::::: : ::::::: :::::::::.:: :::::::::.:::. . XP_006 GDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSL 630 640 650 660 670 680 790 800 810 820 830 840 pF1KB9 RTCMTDFLHSLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEI :. ...::::::::::::: .::: ::::::: ::::.:::.::: . .:.:::: .:. XP_006 RNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEV 690 700 710 720 730 740 850 860 870 880 890 900 pF1KB9 DAHRLNDGGLLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQ :.:::.::::::::.:.::::::::::: ::::::::::::::::::.:.:::::::: : XP_006 DVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQ 750 760 770 780 790 800 910 920 930 940 950 960 pF1KB9 YTVEDGGHVEAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPS : ::::::: ::. :::.:::::.:::.. : : ..:.:::::.:. :::.:...::.:: XP_006 YIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPS 810 820 830 840 850 860 970 980 990 1000 1010 1020 pF1KB9 KVHPAEPFTGELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQK ::. :: :: :: :. . :::::.::: ::.::.:::.:.:::.: :: :.:.::.. XP_006 KVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVER 870 880 890 900 910 920 1030 1040 1050 1060 1070 1080 pF1KB9 LMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATI :: ::: :::::::::.:::::.:::: ::::... :::::::::::::::::::::.: XP_006 LMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANI 930 940 950 960 970 980 1090 1100 1110 1120 1130 1140 pF1KB9 LDCHAATLQRKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQA :: :::::.::..:::::.::::::::::::::::::.::.::.::::.::::: .::.. XP_006 LDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNG 990 1000 1010 1020 1030 1040 1150 1160 1170 1180 1190 1200 pF1KB9 HYDKCVINLREQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISILN ::::::. :::. : ::. ::. :::::::.::: :: ::::.::: ::.:.:::..::. XP_006 HYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILT 1050 1060 1070 1080 1090 1100 1210 1220 1230 1240 1250 1260 pF1KB9 ELTQLSKSEHCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLI :::::::. . ::::::::.:::::::::::::::::::::::::::::::: :::.::: XP_006 ELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLI 1110 1120 1130 1140 1150 1160 1270 1280 1290 1300 1310 1320 pF1KB9 LSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFML ::::.::::::.::::.:.:: ::.:::::::.::::::::.::::: :.:::::::::: XP_006 LSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFML 1170 1180 1190 1200 1210 1220 1330 1340 1350 1360 1370 1380 pF1KB9 PSSHPNRMTVPISITNPDLLRHST--ELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEV :.::::::. .... . . .. ....:..:.: :::::.::.:: ::::.: :::: XP_006 PTSHPNRMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEV 1230 1240 1250 1260 1270 1280 1390 1400 1410 1420 1430 1440 pF1KB9 ISCFANVPKDTPLFSEA-RTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRT ..::.. : ..: : :: .::::.:: : :.::::::::.:. .::. :. ..: XP_006 MGCFSDSPPQSPTFPEAGHTSLYDED--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFRE 1290 1300 1310 1320 1330 1450 1460 1470 1480 pF1KB9 FVQSKKNILVDYGLRRITFLIAQE---------------KEFPKFFTFRARDEFAEDRIY :.:..: :::.:.::.:::.::. .::::::::::::.: ::::: XP_006 FTQQNKATLVDHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIY 1340 1350 1360 1370 1380 1390 1490 1500 1510 1520 1530 1540 pF1KB9 RHLEPALAFQLELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHS :::::::::::::::::::::::.::::::::::::::::. :.::::.:::.::::::: XP_006 RHLEPALAFQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHS 1400 1410 1420 1430 1440 1450 1550 1560 1570 1580 1590 1600 pF1KB9 DLITKEASFEYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEE ::.:::::::::::::::::::::::::::::::.:::::::::::::::::::: :::: XP_006 DLVTKEASFEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEE 1460 1470 1480 1490 1500 1510 1610 1620 1630 1640 1650 1660 pF1KB9 SVRYMVMRYGSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTD ::: ::::::::::::::::::.::::: : ::.:.:::::.:::::::::::::::::: XP_006 SVRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTD 1520 1530 1540 1550 1560 1570 1670 1680 1690 1700 1710 1720 pF1KB9 SRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALF ::...:::...:.:::: ::::::::::::::::.::::::.::::::::.::::::.:. XP_006 SRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLI 1580 1590 1600 1610 1620 1630 1730 1740 1750 1760 1770 1780 pF1KB9 KLWGS-------PDK-YPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQE ::: : :. :.:.:::::::::.:::::.:::::::::.::::.:: ::. : XP_006 KLWESMSTQAFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPE 1640 1650 1660 1670 1680 1690 1790 1800 1810 1820 1830 1840 pF1KB9 YPEGRDVIVIGNDITFRIGSFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEI ::::::.::::::::.::::::: ::::.:::::.:::::::.:::.::::::::.:::: XP_006 YPEGRDIIVIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEI 1700 1710 1720 1730 1740 1750 1850 1860 1870 1880 1890 1900 pF1KB9 KHMFHVAWVDPEDPHKGFKYLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDD .:::::::::::::.::..::::::::: :.:.::::::.:.:. ::::: :::::::.. XP_006 RHMFHVAWVDPEDPYKGYRYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEE 1760 1770 1780 1790 1800 1810 1910 1920 1930 1940 1950 1960 pF1KB9 GLGVENLRGSGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTG :.: :::::::::::::::::.::.::::::::::::::::::::::.:::::::.:::: XP_006 GIGPENLRGSGMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTG 1820 1830 1840 1850 1860 1870 1970 1980 1990 2000 2010 2020 pF1KB9 ASALNKVLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPV :.:::::::::::::::::::.:::: :::.: :: ::::::.:.:.:::::::. :: : XP_006 AGALNKVLGREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSV 1880 1890 1900 1910 1920 1930 2030 2040 2050 2060 2070 2080 pF1KB9 PIITPTDPIDREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQT :... ::::: :::.:...::::::::::::::: :: : :::::.:::.::: ::::: XP_006 PLLNSKDPIDRIIEFVPTKTPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQT 1940 1950 1960 1970 1980 1990 2090 2100 2110 2120 2130 2140 pF1KB9 VVTGRARLGGIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAV ::.::::::::::::.::::::::...::::::::::::::::::::::::::.:: ::. XP_006 VVVGRARLGGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAI 2000 2010 2020 2030 2040 2050 2150 2160 2170 2180 2190 2200 pF1KB9 KDFNREKLPLMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRG :::::: ::::.::::::::::::::::::::::::::::::. ::.:.:::: ::::: XP_006 KDFNREGLPLMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRG 2060 2070 2080 2090 2100 2110 2210 2220 2230 2240 2250 2260 pF1KB9 GSWVVIDATINPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQ :::::::..::: .:::::.::::.:::::::::::::.:::.:.:::.::.: .: :. XP_006 GSWVVIDSSINPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAER 2120 2130 2140 2150 2160 2170 2270 2280 2290 2300 2310 2320 pF1KB9 LGEPDLSDKDRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKT :: :.:: .::.::..:: ::..:.::::::::::::.::::::: :::::::::.::: XP_006 LGTPELSTAERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKT 2180 2190 2200 2210 2220 2230 2330 2340 2350 2360 2370 2380 pF1KB9 ARTFLYWRLRRLLLEDQVKQEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVV .:::.::::::::::: ::..: .:. ::. .::.::::::::.::.::::.::::. . XP_006 SRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDL 2240 2250 2260 2270 2280 2290 2390 2400 2410 2420 2430 2440 pF1KB9 VQWLEQHWQAGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAE ..:::.. :: .:.:.::: ...: ::: ::.::. :::::.: .:...:::::.. XP_006 AEWLEKQLTEEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQ 2300 2310 2320 2330 2340 2350 2450 pF1KB9 RAQVVHLLSTMDSPAST ::.:...:::::::.. XP_006 RAEVIRILSTMDSPST 2360 2370 >>XP_016880043 (OMIM: 200350,613933) PREDICTED: acetyl-C (2383 aa) initn: 11643 init1: 4844 opt: 6471 Z-score: 4741.1 bits: 891.3 E(85289): 0 Smith-Waterman score: 11827; 75.5% identity (90.7% similar) in 2317 aa overlap (171-2457:71-2383) 150 160 170 180 190 pF1KB9 GQQAGSPSKEDKKQANIKRQLMTNFILGSFDDYSSDEDS-VAGSSRESTRKGSR--ASLG .: : :: : .. . ..:: ::.: XP_016 AGGSRGQEFEASLANMVFLEVDIYSDSSVSEDNSEDEISNLVKLDLLEEKEGSLSPASVG 50 60 70 80 90 100 200 210 220 230 240 250 pF1KB9 ALSLEAYLTTGEAETRVPTMRPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGD . .: .. . . .: :::::::::.::..::.: .:::::::::::::::::. XP_016 SDTLSDLGISSLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGN 110 120 130 140 150 160 260 270 280 290 300 310 pF1KB9 RVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY .::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: XP_016 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 170 180 190 200 210 220 320 330 340 350 360 370 pF1KB9 VPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSE ::::::::::::::::::.:::::::::::::::::::::::::::: :::.::.::::. XP_016 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 230 240 250 260 270 280 380 390 400 410 420 430 pF1KB9 AMWALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRI-SVPEDVYDKGCVKD :::::::::::..:::: .:::::::::: :.: :.:.. ::: .::...:.:: ::: XP_016 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFS--KRILNVPQELYEKGYVKD 290 300 310 320 330 440 450 460 470 480 490 pF1KB9 VDEGLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPIFLMKLAQ ::.::.:::..:.:.:::::::::::::::...:.::: ::::::.:.::::::.:.::. XP_016 VDDGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAK 340 350 360 370 380 390 500 510 520 530 540 550 pF1KB9 HARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLAK ..:::::::::::::::.::::::::.:::::::.:::::::: :.:: :::::..::: XP_016 QSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKLAK 400 410 420 430 440 450 560 570 580 590 600 610 pF1KB9 TVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRL :::::::::::::::::::.:::::::::::::::::.:::::::::::::::.::.:. XP_016 MVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRI 460 470 480 490 500 510 620 630 640 650 660 670 pF1KB9 KDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQELNFRS ::::..:: :::: .::.:: .. : :::::::::::::::::::::::::::::::: XP_016 KDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRS 520 530 540 550 560 570 680 690 700 710 720 730 pF1KB9 SKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEY .:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEY 580 590 600 610 620 630 740 750 760 770 780 790 pF1KB9 LINLLETESFQNNDIDTGWLDYLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLH ::.:::::::: : ::::::: :::::::::.:: :::::::::.:::. .:. ...::: XP_016 LIKLLETESFQMNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSVSNFLH 640 650 660 670 680 690 800 810 820 830 840 850 pF1KB9 SLERGQVLPADSLLNLVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGG :::::::::: .::: ::::::: ::::.:::.::: . .:.:::: .:.:.:::.::: XP_016 SLERGQVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGG 700 710 720 730 740 750 860 870 880 890 900 910 pF1KB9 LLLSYNGNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLTQYTVEDGGHV :::::.:.::::::::::: ::::::::::::::::::.:.:::::::: :: ::::::: XP_016 LLLSYDGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHV 760 770 780 790 800 810 920 930 940 950 960 970 pF1KB9 EAGSSYAEMEVMKMIMTLNVQERGRVKYIKRPGAVLEAGCVVARLELDDPSKVHPAEPFT ::. :::.:::::.:::.. : : ..:.:::::.:. :::.:...::.::::. :: : XP_016 FAGQCYAEIEVMKMVMTLTAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSKVQQAELHT 820 830 840 850 860 870 980 990 1000 1010 1020 1030 pF1KB9 GELPAQQTLPILGEKLHQVFHSVLENLTNVMSGFCLPEPVFSIKLKEWVQKLMMTLRHPS : :: :. . :::::.::: ::.::.:::.:.:::.: :: :.:.::..:: ::: :: XP_016 GSLPRIQSTALRGEKLHRVFHYVLDNLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRDPS 880 890 900 910 920 930 1040 1050 1060 1070 1080 1090 pF1KB9 LPLLELQEIMTSVAGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQ :::::::.:::::.:::: ::::... :::::::::::::::::::::.::: :::::. XP_016 LPLLELQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLN 940 950 960 970 980 990 1100 1110 1120 1130 1140 1150 pF1KB9 RKADREVFFINTQSIVQLVQRYRSGIRGYMKTVVLDLLRRYLRVEHHFQQAHYDKCVINL ::..:::::.::::::::::::::::::.::.::.::::.::::: .::..::::::. : XP_016 RKSEREVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFAL 1000 1010 1020 1030 1040 1050 1160 1170 1180 1190 1200 1210 pF1KB9 REQFKPDMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSDELISILNELTQLSKSE ::. : ::. ::. :::::::.::: :: ::::.::: ::.:.:::..::.:::::::. XP_016 REENKSDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDELLNILTELTQLSKTT 1060 1070 1080 1090 1100 1110 1220 1230 1240 1250 1260 1270 pF1KB9 HCKVALRARQILIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDV . ::::::::.:::::::::::::::::::::::::::::::: :::.:::::::.:::: XP_016 NAKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDV 1120 1130 1140 1150 1160 1170 1280 1290 1300 1310 1320 1330 pF1KB9 LPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEFQFMLPSSHPNRMT ::.::::.:.:: ::.:::::::.::::::::.::::: :.:::::::::::.::::::. XP_016 LPNFFYHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRMS 1180 1190 1200 1210 1220 1230 1340 1350 1360 1370 1380 1390 pF1KB9 VPISITNPDLLRHST--ELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFDEVISCFANVPK .... . . .. ....:..:.: :::::.::.:: ::::.: ::::..::.. : XP_016 FSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSDSPP 1240 1250 1260 1270 1280 1290 1400 1410 1420 1430 1440 1450 pF1KB9 DTPLFSEA-RTSLYSEDDCKSLREEPIHILNVSIQCADHLEDEALVPILRTFVQSKKNIL ..: : :: .::::.:: : :.::::::::.:. .::. :. ..: :.:..: : XP_016 QSPTFPEAGHTSLYDED--KVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATL 1300 1310 1320 1330 1340 1350 1460 1470 1480 1490 pF1KB9 VDYGLRRITFLIAQE---------------KEFPKFFTFRARDEFAEDRIYRHLEPALAF ::.:.::.:::.::. .::::::::::::.: :::::::::::::: XP_016 VDHGIRRLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAF 1360 1370 1380 1390 1400 1410 1500 1510 1520 1530 1540 1550 pF1KB9 QLELNRMRNFDLTAVPCANHKMHLYLGAAKVKEGVEVTDHRFFIRAIIRHSDLITKEASF ::::::::::::::.::::::::::::::::. :.::::.:::.:::::::::.:::::: XP_016 QLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASF 1420 1430 1440 1450 1460 1470 1560 1570 1580 1590 1600 1610 pF1KB9 EYLQNEGERLLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPFKIEESVRYMVMRY :::::::::::::::::::::::::.:::::::::::::::::::: ::::::: ::::: XP_016 EYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRY 1480 1490 1500 1510 1520 1530 1620 1630 1640 1650 1660 1670 pF1KB9 GSRLWKLRVLQAEVKINIRQTTTGSAVPIRLFITNESGYYLDISLYKEVTDSRSGNIMFH :::::::::::::.::::: : ::.:.:::::.::::::::::::::::::::...:::. XP_016 GSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQ 1540 1550 1560 1570 1580 1590 1680 1690 1700 1710 1720 1730 pF1KB9 SFGNKQGPQHGMLINTPYVTKDLLQAKRFQAQTLGTTYIYDFPEMFRQALFKLWGS---- ..:.:::: ::::::::::::::::.::::::.::::::::.::::::.:.::: : XP_016 AYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQ 1600 1610 1620 1630 1640 1650 1740 1750 1760 1770 1780 1790 pF1KB9 ---PDK-YPKDILTYTELVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTQEYPEGRDVIV :. :.:.:::::::::.:::::.:::::::::.::::.:: ::. :::::::.:: XP_016 AFLPSPPLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIV 1660 1670 1680 1690 1700 1710 1800 1810 1820 1830 1840 1850 pF1KB9 IGNDITFRIGSFGPGEDLLYLRASEMARAEGIPKIYVAANSGARIGMAEEIKHMFHVAWV ::::::.::::::: ::::.:::::.:::::::.:::.::::::::.::::.:::::::: XP_016 IGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWV 1720 1730 1740 1750 1760 1770 1860 1870 1880 1890 1900 1910 pF1KB9 DPEDPHKGFKYLYLTPQDYTRISSLNSVHCKHIEEGGESRYMITDIIGKDDGLGVENLRG :::::.::..::::::::: :.:.::::::.:.:. ::::: :::::::..:.: ::::: XP_016 DPEDPYKGYRYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRG 1780 1790 1800 1810 1820 1830 1920 1930 1940 1950 1960 1970 pF1KB9 SGMIAGESSLAYEEIVTISLVTCRAIGIGAYLVRLGQRVIQVENSHIILTGASALNKVLG ::::::::::::.::.::::::::::::::::::::::.:::::::.:::::.::::::: XP_016 SGMIAGESSLAYNEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLG 1840 1850 1860 1870 1880 1890 1980 1990 2000 2010 2020 2030 pF1KB9 REVYTSNNQLGGVQIMHYNGVSHITVPDDFEGVYTILEWLSYMPKDNHSPVPIITPTDPI ::::::::::::.:::: :::.: :: ::::::.:.:.:::::::. :: ::... ::: XP_016 REVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPI 1900 1910 1920 1930 1940 1950 2040 2050 2060 2070 2080 2090 pF1KB9 DREIEFLPSRAPYDPRWMLAGRPHPTLKGTWQSGFFDHGSFKEIMAPWAQTVVTGRARLG :: :::.:...::::::::::::::: :: : :::::.:::.::: :::::::.:::::: XP_016 DRIIEFVPTKTPYDPRWMLAGRPHPTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLG 1960 1970 1980 1990 2000 2010 2100 2110 2120 2130 2140 2150 pF1KB9 GIPVGVIAVETRTVEVAVPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAVKDFNREKLP ::::::.::::::::...::::::::::::::::::::::::::.:: ::.:::::: :: XP_016 GIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLP 2020 2030 2040 2050 2060 2070 2160 2170 2180 2190 2200 2210 pF1KB9 LMIFANWRGFSGGMKDMYDQVLKFGAYIVDGLRQYKQPILIYIPPYAELRGGSWVVIDAT ::.::::::::::::::::::::::::::::::. ::.:.:::: ::::::::::::.. XP_016 LMVFANWRGFSGGMKDMYDQVLKFGAYIVDGLRECCQPVLVYIPPQAELRGGSWVVIDSS 2080 2090 2100 2110 2120 2130 2220 2230 2240 2250 2260 2270 pF1KB9 INPLCIEMYADKESRGGVLEPEGTVEIKFRKKDLIKSMRRIDPAYKKLMEQLGEPDLSDK ::: .:::::.::::.:::::::::::::.:::.:.:::.::.: .: :.:: :.:: XP_016 INPRHMEMYADRESRGSVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTA 2140 2150 2160 2170 2180 2190 2280 2290 2300 2310 2320 2330 pF1KB9 DRKDLEGRLKAREDLLLPIYHQVAVQFADFHDTPGRMLEKGVISDILEWKTARTFLYWRL .::.::..:: ::..:.::::::::::::.::::::: :::::::::.:::.:::.:::: XP_016 ERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRL 2200 2210 2220 2230 2240 2250 2340 2350 2360 2370 2380 2390 pF1KB9 RRLLLEDQVKQEILQASGELSHVHIQSMLRRWFVETEGAVKAYLWDNNQVVVQWLEQHWQ ::::::: ::..: .:. ::. .::.::::::::.::.::::.::::. ...:::.. XP_016 RRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLAEWLEKQLT 2260 2270 2280 2290 2300 2310 2400 2410 2420 2430 2440 2450 pF1KB9 AGDGPRSTIRENITYLKHDSVLKTIRGLVEENPEVAVDCVIYLSQHISPAERAQVVHLLS :: .:.:.::: ...: ::: ::.::. :::::.: .:...:::::..::.:...:: XP_016 EEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQHISPTQRAEVIRILS 2320 2330 2340 2350 2360 2370 pF1KB9 TMDSPAST :::::.. XP_016 TMDSPST 2380 2458 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 21:01:19 2016 done: Mon Nov 7 21:01:22 2016 Total Scan time: 19.030 Total Display time: 1.710 Function used was FASTA [36.3.4 Apr, 2011]