FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9022, 1712 aa 1>>>pF1KB9022 1712 - 1712 aa - 1712 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.7417+/-0.0015; mu= -6.4436+/- 0.091 mean_var=563.2373+/-115.222, 0's: 0 Z-trim(113.1): 217 B-trim: 0 in 0/52 Lambda= 0.054042 statistics sampled from 13577 (13786) to 13577 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.423), width: 16 Scan time: 6.720 The best scores are: opt bits E(32554) CCDS41907.1 COL4A2 gene_id:1284|Hs108|chr13 (1712) 12760 1011.5 0 CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707) 5864 473.9 2.2e-132 CCDS14542.1 COL4A6 gene_id:1288|Hs108|chrX (1690) 5194 421.6 1.1e-116 CCDS14541.1 COL4A6 gene_id:1288|Hs108|chrX (1691) 5194 421.6 1.1e-116 CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669) 4883 397.4 2.3e-109 CCDS76009.1 COL4A6 gene_id:1288|Hs108|chrX (1666) 4707 383.6 3e-105 CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690) 4629 377.6 2.1e-103 CCDS76008.1 COL4A6 gene_id:1288|Hs108|chrX (1633) 4446 363.3 4e-99 CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944) 3188 265.5 2e-69 CCDS42829.1 COL4A3 gene_id:1285|Hs108|chr2 (1670) 3122 260.1 4.8e-68 CCDS2297.1 COL3A1 gene_id:1281|Hs108|chr2 (1466) 2870 240.4 3.6e-62 CCDS33350.1 COL5A2 gene_id:1290|Hs108|chr2 (1499) 2855 239.2 8.3e-62 CCDS43452.1 COL11A2 gene_id:1302|Hs108|chr6 (1650) 2815 236.1 7.7e-61 CCDS780.2 COL11A1 gene_id:1301|Hs108|chr1 (1690) 2814 236.1 8.2e-61 CCDS53348.1 COL11A1 gene_id:1301|Hs108|chr1 (1767) 2814 236.1 8.5e-61 CCDS778.1 COL11A1 gene_id:1301|Hs108|chr1 (1806) 2814 236.1 8.6e-61 CCDS11561.1 COL1A1 gene_id:1277|Hs108|chr17 (1464) 2750 231.0 2.4e-59 CCDS12222.1 COL5A3 gene_id:50509|Hs108|chr19 (1745) 2743 230.5 3.9e-59 CCDS8759.1 COL2A1 gene_id:1280|Hs108|chr12 (1418) 2694 226.6 4.8e-58 CCDS41778.1 COL2A1 gene_id:1280|Hs108|chr12 (1487) 2694 226.6 4.9e-58 CCDS6376.1 COL22A1 gene_id:169044|Hs108|chr8 (1626) 2686 226.1 8.1e-58 CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 2651 223.4 5.8e-57 CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 2651 223.4 5.8e-57 CCDS6802.1 COL27A1 gene_id:85301|Hs108|chr9 (1860) 2593 218.9 1.4e-55 CCDS35366.1 COL4A5 gene_id:1287|Hs108|chrX (1691) 2582 218.0 2.3e-55 CCDS14543.1 COL4A5 gene_id:1287|Hs108|chrX (1685) 2571 217.1 4.1e-55 CCDS41353.1 COL24A1 gene_id:255631|Hs108|chr1 (1714) 2521 213.2 6.3e-54 CCDS41297.1 COL16A1 gene_id:1307|Hs108|chr1 (1604) 2287 194.9 1.9e-48 CCDS4970.1 COL19A1 gene_id:1310|Hs108|chr6 (1142) 1777 155.0 1.4e-36 CCDS4971.1 COL9A1 gene_id:1297|Hs108|chr6 ( 921) 1677 147.1 2.6e-34 CCDS47447.1 COL9A1 gene_id:1297|Hs108|chr6 ( 678) 1670 146.4 3.1e-34 CCDS42972.1 COL18A1 gene_id:80781|Hs108|chr21 (1519) 1628 143.5 5.2e-33 CCDS13505.1 COL9A3 gene_id:1299|Hs108|chr20 ( 684) 1607 141.5 9.4e-33 CCDS42971.1 COL18A1 gene_id:80781|Hs108|chr21 (1339) 1584 140.0 5.2e-32 CCDS77643.1 COL18A1 gene_id:80781|Hs108|chr21 (1754) 1582 140.0 6.9e-32 CCDS450.1 COL9A2 gene_id:1298|Hs108|chr1 ( 689) 1556 137.6 1.5e-31 CCDS403.1 COL8A2 gene_id:1296|Hs108|chr1 ( 703) 1448 129.2 5.2e-29 CCDS72756.1 COL8A2 gene_id:1296|Hs108|chr1 ( 638) 1415 126.5 2.9e-28 CCDS44423.2 COL13A1 gene_id:1305|Hs108|chr10 ( 668) 1401 125.5 6.3e-28 CCDS55025.1 COL21A1 gene_id:81578|Hs108|chr6 ( 957) 1388 124.6 1.6e-27 CCDS83099.1 COL21A1 gene_id:81578|Hs108|chr6 ( 954) 1380 124.0 2.5e-27 CCDS58922.1 COL25A1 gene_id:84570|Hs108|chr4 ( 645) 1329 119.8 3e-26 CCDS7554.1 COL17A1 gene_id:1308|Hs108|chr10 (1497) 1315 119.1 1.2e-25 CCDS2934.1 COL8A1 gene_id:1295|Hs108|chr3 ( 744) 1300 117.6 1.6e-25 CCDS44428.2 COL13A1 gene_id:1305|Hs108|chr10 ( 610) 1281 116.1 3.9e-25 CCDS5105.1 COL10A1 gene_id:1300|Hs108|chr6 ( 680) 1281 116.1 4.2e-25 CCDS44425.2 COL13A1 gene_id:1305|Hs108|chr10 ( 686) 1256 114.2 1.6e-24 CCDS76649.1 COL4A1 gene_id:1282|Hs108|chr13 ( 519) 1246 113.3 2.3e-24 CCDS44424.2 COL13A1 gene_id:1305|Hs108|chr10 ( 695) 1224 111.7 9.3e-24 CCDS34682.1 COL1A2 gene_id:1278|Hs108|chr7 (1366) 1202 110.3 4.8e-23 >>CCDS41907.1 COL4A2 gene_id:1284|Hs108|chr13 (1712 aa) initn: 12760 init1: 12760 opt: 12760 Z-score: 5396.0 bits: 1011.5 E(32554): 0 Smith-Waterman score: 12760; 99.9% identity (100.0% similar) in 1712 aa overlap (1-1712:1-1712) 10 20 30 40 50 60 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 ARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPAL 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 YGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 GECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGVPGNIGA ::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::: CCDS41 GECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGA 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 PGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 GDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQID 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 CDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRG ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: CCDS41 CDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRG 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 LPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQ 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGH 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 PGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 PGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGL 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 AGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 AGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLS 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 GIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 YGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 LPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPG 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPG 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 TPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPG 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 APGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 APGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQ 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 GRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 GRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQ 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 EPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 EPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASR 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 NDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NDKSYWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLW 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 IGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 IGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP 1630 1640 1650 1660 1670 1680 1690 1700 1710 pF1KB9 EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL :::::::::::::::::::::::::::::::: CCDS41 EQSFQGSPSADTLKAGLIRTHISRCQVCMKNL 1690 1700 1710 >>CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707 aa) initn: 6777 init1: 2681 opt: 5864 Z-score: 2490.3 bits: 473.9 E(32554): 2.2e-132 Smith-Waterman score: 5865; 51.8% identity (65.2% similar) in 1752 aa overlap (11-1712:3-1707) 10 20 30 40 50 60 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR :.: :::: ::. . . . :: :.. ::::.::::.:::.::::.: CCDS76 MHPGL--WLLL--VTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGAR 10 20 30 40 70 80 90 100 110 120 pF1KB9 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP :.:::.: :: .:: :. : ::.: ::..: : : ::::: : :: :: : .::: CCDS76 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIP 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD ::::: :::: :: :::::::: : :: : :. :::: : ::.::.: : . CCDS76 GHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG ..:.:: ::: :. :: : :: : .::.: :: :::::::: : .:: :::: : :: CCDS76 -MKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 170 180 190 200 210 220 250 260 270 280 pF1KB9 EKGDVGQPGPNGIPSDT--LHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGI--------- ::::: ::: : : .: :. . : : ::: : .: ::: : CCDS76 VKGDVGLPGPAGPPPSTGELEFMGFPKG----KKGSKGEPGPKGFPGISGPPGFPGLGTT 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 ---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPP . :::.:: :.:: :: : : .: :::.:..: :. : .: .: .:. :: : : CCDS76 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB9 GLPAY-SPHPSLAKGARGDPG---FPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGL : .. . .. .: :::: .:: .:. : :: : :.:: :.:: :. CCDS76 GPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS--------GV 350 360 370 380 390 410 420 430 440 450 pF1KB9 PGEMGPKGFIG---DPGIPALYG-GPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGR :: .::.:: : : : :. : : :. : ::::: ::::.:. :.. . CCDS76 PGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE-- 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB9 AGFPGLPGSPGARGP---KGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKG .::::: : : .: :: :::.: : : .: : :: ::: : :. : :: :: CCDS76 SGFPGLRGEQGPKGNLGLKGIKGDSGFCAC-DGGVPNTGPPGEPGPPGPWGLIGLPGLKG 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB9 DKGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDG .:: :. : : : :. : .: :::: ::. : .: :. : : :..: : CCDS76 ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB9 SPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFP ::.::. :.::::: :::: .: ::. : ::.:: :: :: : :: ::::: : ::.: CCDS76 EPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLP 580 590 600 610 620 630 640 650 660 670 680 pF1KB9 GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVG-GD--RQEAIQPGCIA----GPKGL :: : : :: : :: : :: : :: :: ...: :: ::.:. CCDS76 GDKGKDGLPGQQGLPGSKG-----DC---CCREVGKGDLDTERGITLPCIIPGSYGPSGF 640 650 660 670 680 690 700 710 720 730 740 pF1KB9 PGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVG- :: :: ::: :: ::.:: : :. : .: ::. : .: ::: :::: :: : CCDS76 PGTPGFPGP---KGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGF 690 700 710 720 730 740 750 760 770 780 790 800 pF1KB9 --LPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPP ::: :: :: :: :: :: .: :...::. : :. :. : : ::. :: : : CCDS76 PGLPGKDGLPGMIGSPGL---PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLP 750 760 770 780 790 810 820 830 840 850 860 pF1KB9 GFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLP :..: .: ::. : ::. : :: :: : : :: : : :. : : ::.:: : : CCDS76 GLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHP 800 810 820 830 840 850 870 880 890 900 910 920 pF1KB9 GDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSP : .: : : :: . ::: : .: : : : :::: :. :.:. : ::..:: CCDS76 GKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSV 860 870 880 890 900 910 930 940 950 960 970 980 pF1KB9 GMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG :. :: :.::: : :: : :: : : : .: :: :: ::.::.::: : : : CCDS76 GFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP- 920 930 940 950 960 970 990 1000 1010 1020 1030 1040 pF1KB9 MKDI--KGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPG :... ::.::..: : .:. : .: .: : :: :.:: :: :: ::::.: : :: CCDS76 MSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPG 980 990 1000 1010 1020 1030 1050 1060 1070 1080 1090 1100 pF1KB9 IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRP . :. :.::. : :::::::. : :..: : :: : : : :: :.:... : : CCDS76 FMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSP 1040 1050 1060 1070 1080 1090 1110 1120 1130 1140 1150 1160 pF1KB9 GLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQ : ::. : .:. : :: . : :.::::: : .: :..:..:.:: : :: CCDS76 GPKGQPGESGFKGTKG---RDGLIGNIGFPGNK---GEDGKVGVSGDVGLPGAPGFPGVA 1100 1110 1120 1130 1140 1150 1170 1180 1190 1200 1210 pF1KB9 GELGRIGLPGGKGDDGW--P-GAPGL--P-GFPGLRGIRGLHGLPGTKGFPGSPGSDIHG : :. ::::..: .: : :.::: : ::::. :..::.::::::: :.:: .: : CCDS76 GMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITG 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 1270 pF1KB9 DPG---FPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPS :: .::: ::.: :: . :: :. :::::.: :: .:: : :: :::. :: CCDS76 VPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGA---PGISLPS 1220 1230 1240 1250 1260 1280 1290 1300 1310 1320 1330 pF1KB9 NISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQ :.: ::: : ::. : .: :: :::: . ...::::.:: :: :: :: :: : CCDS76 LIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGD---Q 1270 1280 1290 1300 1310 1320 1340 1350 1360 1370 1380 1390 pF1KB9 GRPGVFGLPGE---KGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIA : :: ::::: :: ::: ::::. : .: :: : : :: : :. : : :: . CCDS76 GIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQT 1330 1340 1350 1360 1370 1380 1400 1410 1420 1430 1440 1450 pF1KB9 GIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGF . . : :: .: : : :: :. : ::: : : .: :: : .: .:. . :: CCDS76 PTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGA 1390 1400 1410 1420 1430 1440 1460 1470 1480 1490 1500 1510 pF1KB9 RGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKL :: : : ::: : :::::. : :.:::::.:. .:: ::::::..: : ::.::..: CCDS76 LGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQL 1450 1460 1470 1480 1490 1500 1520 1530 1540 1550 1560 1570 pF1KB9 WSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTA : :::::. ::::::::::::.::::: :::::::.::: ..::.:: :::::::::::: CCDS76 WVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTA 1510 1520 1530 1540 1550 1560 1580 1590 1600 1610 1620 1630 pF1KB9 PLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAA :.:::::.. .: :::::::::::. ::::::::..::.:: ::::::::::::::::: CCDS76 PIPMMPVSQTQIPQYISRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAA 1570 1580 1590 1600 1610 1620 1640 1650 1660 1670 1680 1690 pF1KB9 GDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPE-QSFQGSPSA : :::::::::::::::::::::::::.:.::::::.::::::::::. : :.: : . CCDS76 GAEGGGQSLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVS 1630 1640 1650 1660 1670 1680 1700 1710 pF1KB9 DTLKAGLIRTHISRCQVCMKNL .::::: ..:..::::::::.: CCDS76 ETLKAGQLHTRVSRCQVCMKSL 1690 1700 >>CCDS14542.1 COL4A6 gene_id:1288|Hs108|chrX (1690 aa) initn: 5233 init1: 2671 opt: 5194 Z-score: 2208.1 bits: 421.6 E(32554): 1.1e-116 Smith-Waterman score: 5841; 51.7% identity (65.0% similar) in 1745 aa overlap (11-1712:3-1690) 10 20 30 40 50 60 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR :.: :::: ::. . . . :: :.. ::::.::::.:::.::::.: CCDS14 MHPGL--WLLL--VTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGAR 10 20 30 40 70 80 90 100 110 120 pF1KB9 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP :.:::.: :: .:: :. : ::.: ::..: : : ::::: : :: :: : .::: CCDS14 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIP 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD ::::: :::: :: :::::::: : :: : :. :::: : ::.::.: : . CCDS14 GHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG ..:.:: ::: :. :: : :: : .::.: :: :::::::: : .:: :::: : :: CCDS14 -MKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 170 180 190 200 210 220 250 260 270 280 pF1KB9 EKGDVGQPGPNGIPSDT--LHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGI--------- ::::: ::: : : .: :. . : : ::: : .: ::: : CCDS14 VKGDVGLPGPAGPPPSTGELEFMGFPKG----KKGSKGEPGPKGFPGISGPPGFPGLGTT 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 ---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPP . :::.:: :.:: :: : : .: :::.:..: :. : .: .: .:. :: : : CCDS14 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB9 GLPAY-SPHPSLAKGARGDPG---FPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGL : .. . .. .: :::: .:: .:. : :: : :.:: :.:: :. CCDS14 GPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS--------GV 350 360 370 380 390 410 420 430 440 450 pF1KB9 PGEMGPKGFIG---DPGIPALYG-GPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGR :: .::.:: : : : :. : : :. : ::::: ::::.:. :.. . CCDS14 PGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE-- 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB9 AGFPGLPGSPGARGP---KGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKG .::::: : : .: :: :::.: : : .: : :: ::: : :. : :: :: CCDS14 SGFPGLRGEQGPKGNLGLKGIKGDSGFCAC-DGGVPNTGPPGEPGPPGPWGLIGLPGLKG 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB9 DKGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDG .:: :. : : : :. : .: :::: ::. : .: :. : : :..: : CCDS14 ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB9 SPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFP ::.::. :.::::: :::: .: ::. : ::.:: :: :: : :: ::::: : ::.: CCDS14 EPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLP 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB9 GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPP :: : : :: : :: : . : : :: ::.:.:: :: : CCDS14 GDKGKDGLPGQQGLPGSKGI--TLPC---------------IIPGSY-GPSGFPGTPGFP 640 650 660 670 700 710 720 730 740 750 pF1KB9 GPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVG---LPGPD :: :: ::.:: : :. : .: ::. : .: ::: :::: :: : ::: : CCDS14 GP---KGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKD 680 690 700 710 720 730 760 770 780 790 800 810 pF1KB9 GSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQG : :: :: :: :: .: :...::. : :. :. : : ::. :: : ::..: .: CCDS14 GLPGMIGSPGL---PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 740 750 760 770 780 820 830 840 850 860 870 pF1KB9 MPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPG ::. : ::. : :: :: : : :: : : :. : : ::.:: : :: .: : CCDS14 KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRG 790 800 810 820 830 840 880 890 900 910 920 930 pF1KB9 DTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQG : :: . ::: : .: : : : :::: :. :.:. : ::..:: :. :: : CCDS14 KKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPG 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB9 MPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDI--K .::: : :: : :: : : : .: :: :: ::.::.::: : : : :... : CCDS14 IPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP-MSNLWLK 910 920 930 940 950 960 1000 1010 1020 1030 1040 1050 pF1KB9 GEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGF :.::..: : .:. : .: .: : :: :.:: :: :: ::::.: : ::. :. :. CCDS14 GDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL 970 980 990 1000 1010 1020 1060 1070 1080 1090 1100 1110 pF1KB9 PGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERG ::. : :::::::. : :..: : :: : : : :: :.:... : :: ::. : CCDS14 PGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPG 1030 1040 1050 1060 1070 1080 1120 1130 1140 1150 1160 1170 pF1KB9 TTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIG .:. : :: . : :.::::: : .: :..:..:.:: : :: : :. : CCDS14 ESGFKGTKG---RDGLIGNIGFPGNK---GEDGKVGVSGDVGLPGAPGFPGVAGMRGEPG 1090 1100 1110 1120 1130 1140 1180 1190 1200 1210 1220 pF1KB9 LPGGKGDDGW--P-GAPGL--P-GFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPG---F :::..: .: : :.::: : ::::. :..::.::::::: :.:: .: : :: . CCDS14 LPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGL 1150 1160 1170 1180 1190 1200 1230 1240 1250 1260 1270 1280 pF1KB9 PGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPG ::: ::.: :: . :: :. :::::.: :: .:: : :: :::. :: :.: :: CCDS14 PGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGA---PGISLPSLIAGQPG 1210 1220 1230 1240 1250 1290 1300 1310 1320 1330 1340 pF1KB9 DKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFG : : ::. : .: :: :::: . ...::::.:: :: :: :: :: :: :: : CCDS14 DPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGD---QGIPGFSG 1260 1270 1280 1290 1300 1310 1350 1360 1370 1380 1390 pF1KB9 LPGE---KGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIA :::: :: ::: ::::. : .: :: : : :: : :. : : :: . . . CCDS14 LPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQ 1320 1330 1340 1350 1360 1370 1400 1410 1420 1430 1440 1450 pF1KB9 VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPI : :: .: : : :: :. : ::: : : .: :: : .: .:. . :: :: : CCDS14 VPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLP 1380 1390 1400 1410 1420 1430 1460 1470 1480 1490 1500 1510 pF1KB9 GHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLL : ::: : :::::. : :.:::::.:. .:: ::::::..: : ::.::..:: ::::: CCDS14 GLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLL 1440 1450 1460 1470 1480 1490 1520 1530 1540 1550 1560 1570 pF1KB9 YFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPV . ::::::::::::.::::: :::::::.::: ..::.:: :::::::::::::.::::: CCDS14 FVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPMMPV 1500 1510 1520 1530 1540 1550 1580 1590 1600 1610 1620 1630 pF1KB9 AEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQ .. .: :::::::::::. ::::::::..::.:: :::::::::::::::::: ::::: CCDS14 SQTQIPQYISRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQ 1560 1570 1580 1590 1600 1610 1640 1650 1660 1670 1680 1690 pF1KB9 SLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPE-QSFQGSPSADTLKAGL ::::::::::::::::::::.:.::::::.::::::::::. : :.: : ..::::: CCDS14 SLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQ 1620 1630 1640 1650 1660 1670 1700 1710 pF1KB9 IRTHISRCQVCMKNL ..:..::::::::.: CCDS14 LHTRVSRCQVCMKSL 1680 1690 >>CCDS14541.1 COL4A6 gene_id:1288|Hs108|chrX (1691 aa) initn: 5233 init1: 2671 opt: 5194 Z-score: 2208.1 bits: 421.6 E(32554): 1.1e-116 Smith-Waterman score: 5840; 51.7% identity (65.1% similar) in 1740 aa overlap (16-1712:7-1691) 10 20 30 40 50 60 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR :::: ::. . . . :: :.. ::::.::::.:::.::::.: CCDS14 MLINKLWLLL--VTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGAR 10 20 30 40 70 80 90 100 110 120 pF1KB9 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP :.:::.: :: .:: :. : ::.: ::..: : : ::::: : :: :: : .::: CCDS14 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIP 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD ::::: :::: :: :::::::: : :: : :. :::: : ::.::.: : . CCDS14 GHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG ..:.:: ::: :. :: : :: : .::.: :: :::::::: : .:: :::: : :: CCDS14 -MKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 170 180 190 200 210 220 250 260 270 280 pF1KB9 EKGDVGQPGPNGIPSDT--LHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGI--------- ::::: ::: : : .: :. . : : ::: : .: ::: : CCDS14 VKGDVGLPGPAGPPPSTGELEFMGFPKG----KKGSKGEPGPKGFPGISGPPGFPGLGTT 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 ---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPP . :::.:: :.:: :: : : .: :::.:..: :. : .: .: .:. :: : : CCDS14 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB9 GLPAY-SPHPSLAKGARGDPG---FPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGL : .. . .. .: :::: .:: .:. : :: : :.:: :.:: :. CCDS14 GPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS--------GV 350 360 370 380 390 410 420 430 440 450 pF1KB9 PGEMGPKGFIG---DPGIPALYG-GPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGR :: .::.:: : : : :. : : :. : ::::: ::::.:. :.. . CCDS14 PGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE-- 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB9 AGFPGLPGSPGARGP---KGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKG .::::: : : .: :: :::.: : : .: : :: ::: : :. : :: :: CCDS14 SGFPGLRGEQGPKGNLGLKGIKGDSGFCAC-DGGVPNTGPPGEPGPPGPWGLIGLPGLKG 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB9 DKGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDG .:: :. : : : :. : .: :::: ::. : .: :. : : :..: : CCDS14 ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB9 SPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFP ::.::. :.::::: :::: .: ::. : ::.:: :: :: : :: ::::: : ::.: CCDS14 EPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLP 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB9 GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPP :: : : :: : :: : . : : :: ::.:.:: :: : CCDS14 GDKGKDGLPGQQGLPGSKGI--TLPC---------------IIPGSY-GPSGFPGTPGFP 640 650 660 670 700 710 720 730 740 750 pF1KB9 GPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVG---LPGPD :: :: ::.:: : :. : .: ::. : .: ::: :::: :: : ::: : CCDS14 GP---KGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKD 680 690 700 710 720 730 760 770 780 790 800 810 pF1KB9 GSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQG : :: :: :: :: .: :...::. : :. :. : : ::. :: : ::..: .: CCDS14 GLPGMIGSPGL---PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 740 750 760 770 780 820 830 840 850 860 870 pF1KB9 MPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPG ::. : ::. : :: :: : : :: : : :. : : ::.:: : :: .: : CCDS14 KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRG 790 800 810 820 830 840 880 890 900 910 920 930 pF1KB9 DTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQG : :: . ::: : .: : : : :::: :. :.:. : ::..:: :. :: : CCDS14 KKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPG 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB9 MPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDI--K .::: : :: : :: : : : .: :: :: ::.::.::: : : : :... : CCDS14 IPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP-MSNLWLK 910 920 930 940 950 960 1000 1010 1020 1030 1040 1050 pF1KB9 GEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGF :.::..: : .:. : .: .: : :: :.:: :: :: ::::.: : ::. :. :. CCDS14 GDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL 970 980 990 1000 1010 1020 1060 1070 1080 1090 1100 1110 pF1KB9 PGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERG ::. : :::::::. : :..: : :: : : : :: :.:... : :: ::. : CCDS14 PGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPG 1030 1040 1050 1060 1070 1080 1120 1130 1140 1150 1160 1170 pF1KB9 TTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIG .:. : : :. : :.::::: : .: :..:..:.:: : :: : :. : CCDS14 ESGFKGTK---GRDGLIGNIGFPGNKGE---DGKVGVSGDVGLPGAPGFPGVAGMRGEPG 1090 1100 1110 1120 1130 1140 1180 1190 1200 1210 1220 pF1KB9 LPGGKGDDGW--P-GAPGL--P-GFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPG---F :::..: .: : :.::: : ::::. :..::.::::::: :.:: .: : :: . CCDS14 LPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGL 1150 1160 1170 1180 1190 1200 1230 1240 1250 1260 1270 1280 pF1KB9 PGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPG ::: ::.: :: . :: :. :::::.: :: .:: : :: :::. :: :.: :: CCDS14 PGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGA---PGISLPSLIAGQPG 1210 1220 1230 1240 1250 1290 1300 1310 1320 1330 1340 pF1KB9 DKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFG : : ::. : .: :: :::: . ...::::.:: :: :: :: :: :: :: : CCDS14 DPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGD---QGIPGFSG 1260 1270 1280 1290 1300 1310 1350 1360 1370 1380 1390 pF1KB9 LPGE---KGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIA :::: :: ::: ::::. : .: :: : : :: : :. : : :: . . . CCDS14 LPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQ 1320 1330 1340 1350 1360 1370 1400 1410 1420 1430 1440 1450 pF1KB9 VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPI : :: .: : : :: :. : ::: : : .: :: : .: .:. . :: :: : CCDS14 VPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLP 1380 1390 1400 1410 1420 1430 1460 1470 1480 1490 1500 1510 pF1KB9 GHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLL : ::: : :::::. : :.:::::.:. .:: ::::::..: : ::.::..:: ::::: CCDS14 GLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLL 1440 1450 1460 1470 1480 1490 1520 1530 1540 1550 1560 1570 pF1KB9 YFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPV . ::::::::::::.::::: :::::::.::: ..::.:: :::::::::::::.::::: CCDS14 FVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPMMPV 1500 1510 1520 1530 1540 1550 1580 1590 1600 1610 1620 1630 pF1KB9 AEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQ .. .: :::::::::::. ::::::::..::.:: :::::::::::::::::: ::::: CCDS14 SQTQIPQYISRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQ 1560 1570 1580 1590 1600 1610 1640 1650 1660 1670 1680 1690 pF1KB9 SLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIPE-QSFQGSPSADTLKAGL ::::::::::::::::::::.:.::::::.::::::::::. : :.: : ..::::: CCDS14 SLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQ 1620 1630 1640 1650 1660 1670 1700 1710 pF1KB9 IRTHISRCQVCMKNL ..:..::::::::.: CCDS14 LHTRVSRCQVCMKSL 1680 1690 >>CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669 aa) initn: 3801 init1: 939 opt: 4883 Z-score: 2077.1 bits: 397.4 E(32554): 2.3e-109 Smith-Waterman score: 5527; 49.2% identity (63.1% similar) in 1725 aa overlap (10-1710:2-1667) 10 20 30 40 50 60 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR :: : :::: ... . . :..: :.: : : :.:. :: . CCDS95 MGPRLSVWLLLLPAALLLHEEHSRAAAKG---GCAGSGC-GKCDCHGVKGQK 10 20 30 40 70 80 90 100 110 120 pF1KB9 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP :. : : :: : ::.:: : :: :.::. : ::. : :: : :.::.:: :.: CCDS95 GERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLP 50 60 70 80 90 100 130 140 150 160 170 pF1KB9 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEP-YALPKEER : ::: :: : :: :::::.:. :: :::: ::.: ::: : :.::.: : . CCDS95 GIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB9 DRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVK .:: : ::. : :::: :: : .:: : : ::::::::: :..:. ::.: : : CCDS95 MLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPK 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB9 GEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMG :.::: : :: :.:... . : : :::::..::::..:. ::.: : CCDS95 GDKGDQGVSGPPGVPGQAQ---VQEKG-DFAT---KGEKGQKGEPGFQGMPGVGEKGEPG 230 240 250 260 270 280 300 310 320 330 340 350 pF1KB9 FPGLRGYPGLSG---EKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPS :: :: :: .: :::::: : : : : .::.: ::::: :::::. . . : CCDS95 KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI-VIGTGPL 290 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 LAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPG :: :: :: :: .:::: .: :: :: :::::: . :.::: : :: : : CCDS95 GEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKG---DRG 350 360 370 380 390 420 430 440 450 460 470 pF1KB9 IPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGL----KGAKGRAGFPGLPGSPGARG .:. . :::.:. : ::::: ::::: :. :. : : : ::.::.:: : CCDS95 FPGT--SLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIG 400 410 420 430 440 450 480 490 500 510 520 530 pF1KB9 PKGWKGDAGECRCTEGD-EAIKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGL : ::. :: : : .. .: :: :: : :. :.:: :::.: ::. :. : :: CCDS95 EIGEKGQKGES-CLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGP 460 470 480 490 500 510 540 550 560 570 580 590 pF1KB9 KGVPGNIGAPGPKGAKGDSR-TITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPG .:.:: :: :: :: :. . ::..:.:: :: ::: : ::::::: :.:: : CCDS95 QGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMPGRAGSPGRDGHPGLPGPKG 520 530 540 550 560 570 600 610 620 630 640 pF1KB9 PPGD-GIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGP ::. :.:: : :: :.::..: : :::: : : :.. :.::.:: :: : CCDS95 SPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDK---GQAGFPGGPGSPGL 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 PGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPPGPTGAKGLRGIPGF ::: : ::.: : . :: : :::: :: : .: ::.:: CCDS95 PGPKGEPGKI------------------VP--LPGPPGAEGLPGSPGFPGPQGDRGFPGT 640 650 660 670 710 720 730 740 750 760 pF1KB9 AGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGE : : :: .: :. : ::::::: : : : .: :: : :: :::: : :. CCDS95 PGRPGLPGEKGAVGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQ 680 690 700 710 720 730 770 780 790 800 810 820 pF1KB9 RGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPS .: :: : :: .: :.:: :: : :. : :: : .: : :::.: : ::: CCDS95 KGEPGVGL---PGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPP 740 750 760 770 780 830 840 850 860 870 880 pF1KB9 GQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDR : :: : ::. :. : :: .:: : : :: : :: .:. : : :: . : : .::. CCDS95 GLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPG-LDMPGPKGDK 790 800 810 820 830 840 890 900 910 920 930 940 pF1KB9 GDAGF---TGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSK : :. ::..: :: :: .: :.:: :: ::. : : : : :: : ::.:: : CCDS95 GAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEK 850 860 870 880 890 900 950 960 970 980 990 1000 pF1KB9 GEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILP-GMKDIKGEKGDEGPMGLKGYL :. :: :: .: :.::.::..:: : :: : . : ..::.:::.: : : . CCDS95 GDHGF---PGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPI 910 920 930 940 950 960 1010 1020 1030 1040 1050 1060 pF1KB9 GAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGF : :: .: :: ::. : : :.::. : ::: :. : :: ::.:: : : :.:: CCDS95 GEKGSRGDPGTPGVPGKDGQAGQPGQ-PGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGT 970 980 990 1000 1010 1020 1070 1080 1090 1100 1110 1120 pF1KB9 IGSRGDKGAPG---RAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFG : .: : :: :: :. :: :. :. : : :::.::.: :: :. : : CCDS95 PGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI--GIPGLRGEKGDQGIAGFPGSPG 1030 1040 1050 1060 1070 1130 1140 1150 1160 1170 1180 pF1KB9 EKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPG ::: .:.::.::. : :..: :: : : ::: : :..: : :.:: ::. : :: CCDS95 EKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPG 1080 1090 1100 1110 1120 1130 1190 1200 1210 1220 1230 1240 pF1KB9 APGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVG .:: : : .: : :.::. : : :: .: ::::: :..:. ::.. .:: .: CCDS95 TPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVG-FPGLAG 1140 1150 1160 1170 1180 1190 1250 1260 1270 1280 1290 1300 pF1KB9 VPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPG :: :..: : :::: : :.:: .: : ::.: : :: : :: :::: CCDS95 SPGIPGSKGEQGFMGPPGPQGQPGLPG-SPGHATEGPKGDRGPQGQPGLPGLPGPMGPPG 1200 1210 1220 1230 1240 1250 1310 1320 1330 1340 1350 pF1KB9 SAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPG---EKGPRGEQGFMGNTG .. : ::: :::: ::.::. : :: : :: ::. : :: :: : : : : CCDS95 LPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQG 1260 1270 1280 1290 1300 1310 1360 1370 1380 1390 1400 1410 pF1KB9 PTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEM : : : .: :: .:: : ::: : : :: : . : .:: ::.: ::: : . CCDS95 PKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEG---PPGLKGLQ 1320 1330 1340 1350 1360 1370 1420 1430 1440 1450 1460 1470 pF1KB9 GPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLP : :: :. : : : :: : : ...:: .:. :: : :: : : :: : :: CCDS95 GLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSM 1380 1390 1400 1410 1420 1430 1480 1490 1500 1510 1520 1530 pF1KB9 GMPGR-SVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCL : :: ::. :.:...:::: ..:.:: : . :. :::::: .:.:.::.:::: ::::: CCDS95 GPPGTPSVDHGFLVTRHSQTIDDPQCPSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCL 1440 1450 1460 1470 1480 1490 1540 1550 1560 1570 1580 1590 pF1KB9 ARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPM--MPVAEDEIKPYISRCSVCEAP .:::::::.:: ..:: .::::: :::::: :.:: :.. ..:.:.::::.::::: CCDS95 RKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPITGENIRPFISRCAVCEAP 1500 1510 1520 1530 1540 1550 1600 1610 1620 1630 1640 1650 pF1KB9 AIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLEDFRATPFI :...::::: ..:: ::.:: ::::::::.:::.:: ::.::.:.:::::::.::..::: CCDS95 AMVMAVHSQTIQIPPCPSGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFI 1560 1570 1580 1590 1600 1610 1660 1670 1680 1690 1700 1710 pF1KB9 ECNGGRGTCHYYANKYSFWLTTIPEQSFQGSPSADTLKAGLIRTHISRCQVCMKNL ::.: ::::.:::: :::::.:: .. . .:. .::::: .:::.:::::::. CCDS95 ECHG-RGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT 1620 1630 1640 1650 1660 >>CCDS76009.1 COL4A6 gene_id:1288|Hs108|chrX (1666 aa) initn: 3575 init1: 2249 opt: 4707 Z-score: 2002.9 bits: 383.6 E(32554): 3e-105 Smith-Waterman score: 5730; 51.1% identity (64.3% similar) in 1736 aa overlap (11-1712:3-1666) 10 20 30 40 50 60 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR :.: :::: ::. . . . :: :.. ::::.::::.:::.::::.: CCDS76 MHPGL--WLLL--VTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGAR 10 20 30 40 70 80 90 100 110 120 pF1KB9 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP :.:::.: :: .:: :. : ::.: ::..: : : ::::: : :: :: : .::: CCDS76 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIP 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD ::::: :::: :: :::::::: : :: : :. :::: : ::.::.: : . CCDS76 GHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG ..:.:: ::: :. :: : :: : .::.: :: :::::::: : .:: :::: : :: CCDS76 -MKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 170 180 190 200 210 220 250 260 270 280 pF1KB9 EKGDVGQPGPNGIPSDT--LHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGI--------- ::::: ::: : : .: :. . : : ::: : .: ::: : CCDS76 VKGDVGLPGPAGPPPSTGELEFMGFPKG----KKGSKGEPGPKGFPGISGPPGFPGLGTT 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 ---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPP . :::.:: :.:: :: : : .: :::.:..: :. : .: .: .:. :: : : CCDS76 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB9 GLPAY-SPHPSLAKGARGDPG---FPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGL : .. . .. .: :::: .:: .:. : :: : :.:: :.:: :. CCDS76 GPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS--------GV 350 360 370 380 390 410 420 430 440 450 pF1KB9 PGEMGPKGFIG---DPGIPALYG-GPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGR :: .::.:: : : : :. : : :. : ::::: ::::.:. :.. . CCDS76 PGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE-- 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB9 AGFPGLPGSPGARGP---KGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKG .::::: : : .: :: :::.: : : .: : :: ::: : :. : :: :: CCDS76 SGFPGLRGEQGPKGNLGLKGIKGDSGFCAC-DGGVPNTGPPGEPGPPGPWGLIGLPGLKG 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB9 DKGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDG .:: :. : : : :. : .: :::: ::. : .: :. : : :..: : CCDS76 ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB9 SPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFP ::.::. :.::::: :::: .: ::. : ::.:: :: :: : :: ::::: : ::.: CCDS76 EPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLP 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB9 GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPP :: : : :: : :: : . : : :: ::.:.:: :: : CCDS76 GDKGKDGLPGQQGLPGSKGI--TLPC---------------IIPGSY-GPSGFPGTPGFP 640 650 660 670 700 710 720 730 740 750 pF1KB9 GPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVG---LPGPD :: :: ::.:: : :. : .: ::. : .: ::: :::: :: : ::: : CCDS76 GP---KGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKD 680 690 700 710 720 730 760 770 780 790 800 810 pF1KB9 GSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQG : :: :: :: :: .: :...::. : :. :. : : ::. :: : ::..: .: CCDS76 GLPGMIGSPGL---PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 740 750 760 770 780 820 830 840 850 860 870 pF1KB9 MPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPG ::. : ::. : :: :: : : :: : : :. : : ::.:: : :: .: : CCDS76 KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRG 790 800 810 820 830 840 880 890 900 910 920 930 pF1KB9 DTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQG : :: . ::: : .: : : : :::: :. :.:. : ::..:: :. :: : CCDS76 KKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPG 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB9 MPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDI--K .::: : :: : :: : : : .: :: :: ::.::.::: : : : :... : CCDS76 IPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP-MSNLWLK 910 920 930 940 950 960 1000 1010 1020 1030 1040 1050 pF1KB9 GEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGF :.::..: : .:. : .: .: : :: :.:: :: :: ::::.: : ::. :. :. CCDS76 GDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL 970 980 990 1000 1010 1020 1060 1070 1080 1090 1100 1110 pF1KB9 PGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERG ::. : :::::::. : :..: : :: : : : :: :.:... : :: ::. : CCDS76 PGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPG 1030 1040 1050 1060 1070 1080 1120 1130 1140 1150 1160 1170 pF1KB9 TTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIG .:. : :: . : :.::::: : .: :..:..:.:: : :: : :. : CCDS76 ESGFKGTKG---RDGLIGNIGFPGNK---GEDGKVGVSGDVGLPGAPGFPGVAGMRGEPG 1090 1100 1110 1120 1130 1140 1180 1190 1200 1210 1220 1230 pF1KB9 LPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGD :::..: .: : : ::. : .: :. : :: :. :.::: ::.: CCDS76 LPGSSGHQGAIGPLGSPGLIGPKG-------PSITGVPG-PA-------GLPGPKGEKGY 1150 1160 1170 1180 1240 1250 1260 1270 1280 1290 pF1KB9 PGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFG :: . :: :. :::::.: :: .:: : :: :::. :: :.: ::: : ::. : CCDS76 PGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGA---PGISLPSLIAGQPGDPGRPGLDG 1190 1200 1210 1220 1230 1240 1300 1310 1320 1330 1340 pF1KB9 LKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGE---KG .: :: :::: . ...::::.:: :: :: :: :: :: :: ::::: :: CCDS76 ERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGD---QGIPGFSGLPGELGLKG 1250 1260 1270 1280 1290 1300 1350 1360 1370 1380 1390 1400 pF1KB9 PRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQ ::: ::::. : .: :: : : :: : :. : : :: . . . : :: .: CCDS76 MRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLP 1310 1320 1330 1340 1350 1360 1410 1420 1430 1440 1450 1460 pF1KB9 GRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQE : : :: :. : ::: : : .: :: : .: .:. . :: :: : : ::: : : CCDS76 GIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFE 1370 1380 1390 1400 1410 1420 1470 1480 1490 1500 1510 1520 pF1KB9 GAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAH ::::. : :.:::::.:. .:: ::::::..: : ::.::..:: :::::. ::::::: CCDS76 GAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEKAH 1430 1440 1450 1460 1470 1480 1530 1540 1550 1560 1570 1580 pF1KB9 NQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYI :::::.::::: :::::::.::: ..::.:: :::::::::::::.:::::.. .: :: CCDS76 NQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPMMPVSQTQIPQYI 1490 1500 1510 1520 1530 1540 1590 1600 1610 1620 1630 1640 pF1KB9 SRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCL :::::::::. ::::::::..::.:: :::::::::::::::::: :::::::::::::: CCDS76 SRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQSLVSPGSCL 1550 1560 1570 1580 1590 1600 1650 1660 1670 1680 1690 1700 pF1KB9 EDFRATPFIECNGGRGTCHYYANKYSFWLTTIPE-QSFQGSPSADTLKAGLIRTHISRCQ :::::::::::.:.::::::.::::::::::. : :.: : ..::::: ..:..:::: CCDS76 EDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQLHTRVSRCQ 1610 1620 1630 1640 1650 1660 1710 pF1KB9 VCMKNL ::::.: CCDS76 VCMKSL >>CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690 aa) initn: 2851 init1: 1100 opt: 4629 Z-score: 1970.0 bits: 377.6 E(32554): 2.1e-103 Smith-Waterman score: 5464; 49.7% identity (62.0% similar) in 1745 aa overlap (16-1710:24-1688) 10 20 30 40 50 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQ : : . . : .: : .. ::. :::::::: :. CCDS42 MWSLHIVLMRCSFRLTKSLATGPWSL---ILILFSVQYVYGSGKKYIGPCGGRDCSV-CH 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 CYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSG : ::::.:: ::: :::: :: : : ::.:.:: .:.:: ::..: ::: : :: : CCDS42 CVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 FPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPY ::: :::::::: ::::.::..: ::..:: : : :. : :: : : ::.::. CCDS42 FPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSV 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 ALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRG . . .:. :.::: :. :: : : ::.: ::.:: :::: :. : .: CCDS42 FILGAVKG-IQGDRGDPGLPGL---PGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKG 180 190 200 210 220 230 240 250 260 270 280 pF1KB9 LGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPD--QYKGEKGSEGEPGI---- ::::. :: :. : .: :. :: .. : :: :::::: .: ::. CCDS42 NPGVGVKGQMGDPGEVGQQGSPGPTL--LVEP------PDFCLYKGEKGIKGIPGMVGLP 240 250 260 270 280 290 300 310 320 330 pF1KB9 --------RGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKG ::. :::.:: :::: :: :: : : :: :: :: : : : :::: CCDS42 GPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKG 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB9 EAGD---PGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGD . :. :::::. . : : :: ::::::: :: :. : :: ::: : :: . . CCDS42 DPGNRGHPGPPGVLVTPPLP--LKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA- 350 360 370 380 390 400 400 410 420 430 440 pF1KB9 GDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPD---GKRGPPGPPGLPGPPGPDGF---- :. : ::.:: : ::.:. : : :: :: : :: ::::: :: .:. CCDS42 -----GMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSS 410 420 430 440 450 450 460 470 480 490 500 pF1KB9 -LFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGI .. : : :. : : ::.::::: ::. : : : : . : ::::: .: : CCDS42 VIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGD 460 470 480 490 500 510 510 520 530 540 550 560 pF1KB9 NGEPGRKGDKGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGV : :: : ::::: : : ::: : : : :: :::::: . .::..:. : : CCDS42 LGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGP 520 530 540 550 560 570 570 580 590 600 610 620 pF1KB9 PGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPG ::. :. :: :::: : : :::::: . :: :.:: : : : .::::::.:: CCDS42 PGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPG 580 590 600 610 620 630 630 640 650 660 670 680 pF1KB9 LKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQ-IDCDTDVKRAVGGDRQEAIQPGCIAGPK :.:: :: .:: :: :: : : :. :.:.. :: :: CCDS42 PPGERGHPG---VPGHPGVRGPDGLKGQKGDTISCNV-------------TYPGR-HGP- 640 650 660 670 690 700 710 720 730 740 pF1KB9 GLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAV ::. ::::: : : .: ::..:.: : .: :: : .:::::: ::. : CCDS42 --PGFDGPPGPKGFPGPQGAPGLSGSD---GHKGRPGTPGTAEIPGPPGF---RGDMGDP 680 690 700 710 720 730 750 760 770 780 790 800 pF1KB9 GLPGPDGSPGPIGLPGPDGPPG---ERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRG :. : :: .:.: ::: : :: ..:.::. .. :: : :. : ::.:: :: : CCDS42 GFGGEKGS-SPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPG 740 750 760 770 780 810 820 830 840 850 860 pF1KB9 PPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREG :: .: :.::. :::: : : .: ::. :::: :::: : :::: :: : CCDS42 CPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPG 790 800 810 820 830 840 870 880 890 900 910 920 pF1KB9 LPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRG :: .:.:::.: :::.::::: : : : : : :: :: : ::.:: :: :: :: CCDS42 APGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRG 850 860 870 880 890 900 930 940 950 960 970 980 pF1KB9 SPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVIL : :: :.:: .:.:: : : : : :..:: :. :..:..: :::: . CCDS42 LP---GFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEM- 910 920 930 940 950 960 990 1000 1010 1020 1030 1040 pF1KB9 PGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPG .. . :: :. :: : :. : .: .: ::. : : :: : :: .: :. : :: CCDS42 -AIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPG 970 980 990 1000 1010 1020 1050 1060 1070 1080 1090 1100 pF1KB9 IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRP :: :: :: .: :. ::::. :..:. :.:: :. : :: : :. :: . : : CCDS42 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1030 1040 1050 1060 1070 1080 1110 1120 1130 1140 1150 1160 pF1KB9 GLKGERGTTGIPGLKGFFGEKGT---EGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPP : ::: :. : :: : ::.: .: : :: : : .:::: :. :.::: : : CCDS42 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQP 1090 1100 1110 1120 1130 1140 1170 1180 1190 1200 1210 1220 pF1KB9 GSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPG : .:. : :: .:: : :: ::. : : :. ::::: : :: :. : : :: CCDS42 GEMGDPGPRGL---QGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPG 1150 1160 1170 1180 1190 1200 1230 1240 1250 1260 1270 pF1KB9 ---FPGPPGERGDPGEANTLPG--PVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSN .:: ::::::: :: : : :.:: : :: :::: : : :.. CCDS42 PVGIPGLKGERGDPGS----PGISPPGPRGKKGPPGPPGSSGPPGPAGATG----RAPKD 1210 1220 1230 1240 1250 1280 1290 1300 1310 1320 1330 pF1KB9 IS--GAPGDKGAPGIFGLKGYRGPPGPPGSAAL-PGSKGDTGNPGAPGTPGTKGWAGDSG : : :::.: :: : .: :::: :::. : : :: : :: :: :: CCDS42 IPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPG--------- 1260 1270 1280 1290 1300 1340 1350 1360 1370 1380 1390 pF1KB9 PQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAG : : :: :.:: : :..: .: :: : : :: : :: :: :: : .: :: : CCDS42 PPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRG 1310 1320 1330 1340 1350 1360 1400 1410 1420 1430 1440 pF1KB9 IPQKIAVQPGTVGPQGR-RGPPGAPGEMGPQGPPGEPGFRG--APGKAGPQGRGGVSAVP : :. : : : ::::: ::.: : ::.:: .:: : : : .: CCDS42 EPGP----PADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVD 1370 1380 1390 1400 1410 1420 1450 1460 1470 1480 1490 1500 pF1KB9 GFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPG-RSVSIGYL----LVKHSQTDQEPMC : :. :: :..: :..: :: :: :: : :: .. . ::: :: :::::::: : CCDS42 GVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTDQEPTC 1430 1440 1450 1460 1470 1480 1510 1520 1530 1540 1550 1560 pF1KB9 PVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKS :.:: .::.::::::.:::::::::::::::::: :::.:: ::: .::.::.:::.: CCDS42 PLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRS 1490 1500 1510 1520 1530 1540 1570 1580 1590 1600 1610 1620 pF1KB9 YWLSTTAPLPMMPVAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYS :::...:::::::..:. :.::.:::.:::::: :.:::::: ::: :: ::::::::: CCDS42 YWLASAAPLPMMPLSEEAIRPYVSRCAVCEAPAQAVAVHSQDQSIPPCPQTWRSLWIGYS 1550 1560 1570 1580 1590 1600 1630 1640 1650 1660 1670 1680 pF1KB9 FLMHTAAGDEGGGQSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTIP-EQS :::::.:::.::::.:.:::::::::::.::.::.: .::::..::::::::::. . . CCDS42 FLMHTGAGDQGGGQALMSPGSCLEDFRAAPFLECQGRQGTCHFFANKYSFWLTTVKADLQ 1610 1620 1630 1640 1650 1660 1690 1700 1710 pF1KB9 FQGSPSADTLKAGLI-RTHISRCQVCMKNL :...:. :::: . : .:::::::.: CCDS42 FSSAPAPDTLKESQAQRQKISRCQVCVKYS 1670 1680 1690 >>CCDS76008.1 COL4A6 gene_id:1288|Hs108|chrX (1633 aa) initn: 3121 init1: 1795 opt: 4446 Z-score: 1893.1 bits: 363.3 E(32554): 4e-99 Smith-Waterman score: 5628; 50.7% identity (64.0% similar) in 1734 aa overlap (11-1712:3-1633) 10 20 30 40 50 60 pF1KB9 MGRDQRAVAGPALRRWLLLGTVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGR :.: :::: ::. . . . :: :.. ::::.::::.:::.::::.: CCDS76 MHPGL--WLLL--VTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGAR 10 20 30 40 70 80 90 100 110 120 pF1KB9 GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIP :.:::.: :: .:: :. : ::.: ::..: : : ::::: : :: :: : .::: CCDS76 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIP 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB9 GHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERD ::::: :::: :: :::::::: : :: : :. :::: : ::.::.: : . CCDS76 GHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB9 RYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKG ..:.:: ::: :. :: : :: : .::.: :: :::::::: : .:: :::: : :: CCDS76 -MKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 170 180 190 200 210 220 250 260 270 280 pF1KB9 EKGDVGQPGPNGIPSDT--LHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGI--------- ::::: ::: : : .: :. . : : ::: : .: ::: : CCDS76 VKGDVGLPGPAGPPPSTGELEFMGFPKG----KKGSKGEPGPKGFPGISGPPGFPGLGTT 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB9 ---SLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPP . :::.:: :.:: :: : : .: :::.:..: :. : .: .: .:. :: : : CCDS76 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 290 300 310 320 330 340 350 360 370 380 390 400 pF1KB9 GLPAY-SPHPSLAKGARGDPG---FPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGL : .. . .. .: :::: .:: .:. : :: : :.:: :.:: :. CCDS76 GPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS--------GV 350 360 370 380 390 410 420 430 440 450 pF1KB9 PGEMGPKGFIG---DPGIPALYG-GPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGR :: .::.:: : : : :. : : :. : ::::: ::::.:. :.. . CCDS76 PGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE-- 400 410 420 430 440 450 460 470 480 490 500 510 pF1KB9 AGFPGLPGSPGARGP---KGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKG .::::: : : .: :: :::.: : : .: : :: ::: : :. : :: :: CCDS76 SGFPGLRGEQGPKGNLGLKGIKGDSGFCAC-DGGVPNTGPPGEPGPPGPWGLIGLPGLKG 460 470 480 490 500 510 520 530 540 550 560 570 pF1KB9 DKGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDG .:: :. : : : :. : .: :::: ::. : .: :. : : :..: : CCDS76 ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 520 530 540 550 560 570 580 590 600 610 620 630 pF1KB9 SPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFP ::.::. :.::::: :::: .: ::. : ::.:: :: :: : :: ::::: : ::.: CCDS76 EPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLP 580 590 600 610 620 630 640 650 660 670 680 690 pF1KB9 GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPP :: : : :: : :: : . : : :: ::.:.:: :: : CCDS76 GDKGKDGLPGQQGLPGSKGI--TLPC---------------IIPGSY-GPSGFPGTPGFP 640 650 660 670 700 710 720 730 740 750 pF1KB9 GPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVG---LPGPD :: :: ::.:: : :. : .: ::. : .: ::: :::: :: : ::: : CCDS76 GP---KGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKD 680 690 700 710 720 730 760 770 780 790 800 810 pF1KB9 GSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQG : :: :: :: :: .: :...::. : :. :. : : ::. :: : ::..: .: CCDS76 GLPGMIGSPGL---PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 740 750 760 770 780 820 830 840 850 860 870 pF1KB9 MPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPG ::. : ::. : :: :: : : :: : : :. : : ::.:: : :: .: : CCDS76 KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRG 790 800 810 820 830 840 880 890 900 910 920 930 pF1KB9 DTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQG : :: . ::: : .: : : : :::: :. :.:. : ::..:: :. :: : CCDS76 KKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPG 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB9 MPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDI--K .::: : :: : :: : : : .: :: :: ::.::.::: : : : :... : CCDS76 IPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP-MSNLWLK 910 920 930 940 950 960 1000 1010 1020 1030 1040 1050 pF1KB9 GEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGF :.::..: : .:. : .: .: : :: :.:: :: :: ::::.: : ::. :. :. CCDS76 GDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL 970 980 990 1000 1010 1020 1060 1070 1080 1090 1100 1110 pF1KB9 PGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERG ::. : :::::::. : :..: : :: : : : :: :.:... : :: ::. : CCDS76 PGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPG 1030 1040 1050 1060 1070 1080 1120 1130 1140 1150 1160 1170 pF1KB9 TTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIG .:. : :: . : :.::::: : .: :..:..:.:: : :: : :. : CCDS76 ESGFKGTKG---RDGLIGNIGFPGNK---GEDGKVGVSGDVGLPGAPGFPGVAGMRGEPG 1090 1100 1110 1120 1130 1140 1180 1190 1200 1210 1220 1230 pF1KB9 LPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGD :::..: .: : : ::. : .: :. : :: :. :.::: ::.: CCDS76 LPGSSGHQGAIGPLGSPGLIGPKG-------PSITGVPG-PA-------GLPGPKGEKGY 1150 1160 1170 1180 1240 1250 1260 1270 1280 1290 pF1KB9 PGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFG :: . :: :. :::::.: :: .:: : :: :::. :: :.: ::: : ::. : CCDS76 PGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGA---PGISLPSLIAGQPGDPGRPGLDG 1190 1200 1210 1220 1230 1240 1300 1310 1320 1330 1340 1350 pF1KB9 LKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRG .: :: :::: . ...::::.:: :: :: :: :: :: :: ::::: : .: CCDS76 ERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGD---QGIPGFSGLPGELGLKG 1250 1260 1270 1280 1290 1300 1360 1370 1380 1390 1400 pF1KB9 EQGFMGNTGPTG-AVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGR .:..:. : : : . . : :: : ::. : :: .: :: : : :: :: CCDS76 SSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQG-P---------VGLQGS 1310 1320 1330 1340 1350 1410 1420 1430 1440 1450 1460 pF1KB9 RGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGA .: :: ::. ::.: :: :: : :: .::. ::: : ::: CCDS76 KGLPGIPGKDGPSGLPGPPGALGDPG------------LPGL---------QGPPGFEGA 1360 1370 1380 1470 1480 1490 1500 1510 1520 pF1KB9 PGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQ ::. : :.:::::.:. .:: ::::::..: : ::.::..:: :::::. ::::::::: CCDS76 PGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEKAHNQ 1390 1400 1410 1420 1430 1440 1530 1540 1550 1560 1570 1580 pF1KB9 DLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTAPLPMMPVAEDEIKPYISR :::.::::: :::::::.::: ..::.:: :::::::::::::.:::::.. .: :::: CCDS76 DLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIPMMPVSQTQIPQYISR 1450 1460 1470 1480 1490 1500 1590 1600 1610 1620 1630 1640 pF1KB9 CSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGGQSLVSPGSCLED :::::::. ::::::::..::.:: :::::::::::::::::: :::::::::::::::: CCDS76 CSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQSLVSPGSCLED 1510 1520 1530 1540 1550 1560 1650 1660 1670 1680 1690 1700 pF1KB9 FRATPFIECNGGRGTCHYYANKYSFWLTTIPE-QSFQGSPSADTLKAGLIRTHISRCQVC :::::::::.:.::::::.::::::::::. : :.: : ..::::: ..:..:::::: CCDS76 FRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQLHTRVSRCQVC 1570 1580 1590 1600 1610 1620 1710 pF1KB9 MKNL ::.: CCDS76 MKSL 1630 >>CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944 aa) initn: 757 init1: 757 opt: 3188 Z-score: 1359.8 bits: 265.5 E(32554): 2e-69 Smith-Waterman score: 3736; 42.9% identity (54.6% similar) in 1594 aa overlap (51-1483:1247-2763) 30 40 50 60 70 80 pF1KB9 TVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGF : : :: .:.:: .: .: :::: CCDS27 DDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGD--- 1220 1230 1240 1250 1260 1270 90 100 110 120 130 140 pF1KB9 PGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGT ::: :: : ::: :: :.. :.: ::::::: :: ::..: : :: : .:. CCDS27 PGLPGRTG------APGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGS 1280 1290 1300 1310 1320 150 160 170 180 190 pF1KB9 QGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPG-LVGFQGPPG : ::.: :: .: :.:::: ::: :: ..: .:: : CCDS27 PGLPGPRGDPGERG------PRGPKG------------------EPGAPGQVIGGEGP-G 1330 1340 1350 1360 200 210 220 230 240 250 pF1KB9 RPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPN--GI-PSD ::. :. :: : :: :: : :::.: : : .. : ::..:. : :::. :: :.. CCDS27 LPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGE 1370 1380 1390 1400 1410 1420 260 270 280 290 300 310 pF1KB9 TLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSP : :. : : .: : :: .: . .:.: :.:: : :: .: .: : CCDS27 PGLP-----GLPGSP----GPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPP 1430 1440 1450 1460 1470 320 330 340 350 360 370 pF1KB9 GQKGSRGLDGYQGPDGPRGPKGEAGDPGPPG---LPAYSPHPSLAKGARGDPGFPGAQGE : : .: :. :: : : ::: : ::: : ::. . .:. ::: .: :: : ::: CCDS27 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPG-AKGPEGPPGPTGRQGE 1480 1490 1500 1510 1520 1530 380 390 400 410 420 pF1KB9 PGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIG---DPGIPALY-GGPPGPDG : :.::::.. :: ... ..: : ::.: : . : :.: : ::: : CCDS27 KGEPGRPGDPAVVGP---AVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1540 1550 1560 1570 1580 430 440 450 460 470 480 pF1KB9 KRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGD : :: :: : :: : .: :. : :: :: :: ::.: :..:: .:: CCDS27 DPGDRGPIGLTGRAGPPG----DSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE----KGD 1590 1600 1610 1620 1630 1640 490 500 510 520 530 540 pF1KB9 EAIKGLPGLPGPKGFAGINGEPG------RKGDKGDPGQHGLPGFPGLKGVPGNIGAPGP :. : ::::: : :. : :: .:::.::::. : : :: .: :. : ::: CCDS27 EGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGP 1650 1660 1670 1680 1690 1700 550 560 570 580 590 pF1KB9 KGAKG---DS----RTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-G : : :. : :.::: : : : : :.::. :..:: : ::: :: : CCDS27 PGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG 1710 1720 1730 1740 1750 1760 600 610 620 630 640 650 pF1KB9 IKGPPGDPGYPGIPGTKGTPGEMGPPGLGLP----GLKGQRGFPGDAGLPGPPGFLGPPG ..:: :. : : :: : : : :: . : : :. : :: :::: : : :: CCDS27 VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG 1770 1780 1790 1800 1810 1820 660 670 680 690 700 710 pF1KB9 PAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPPGPTGAKGLRGIPGFAG :.: :: . : : .:: . : .: :: :: : : :: : : : CCDS27 PSGPPG-----------LPGKPGEDGKPG-LNGKNGEPGDPGEDGRKGEKGDSGASGREG 1830 1840 1850 1860 720 730 740 750 760 pF1KB9 ADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPG---PDGSPGPIGLPGPDGPPG :: : :: :: : .: :: :: .:: : .: :.:: : :. : : : .: :: CCDS27 RDGPKGERGAPGILGPQGPPGLPGPVGPPG-QGFPGVPGGTGPKGDRGETGSKGEQGLPG 1870 1880 1890 1900 1910 1920 770 780 790 pF1KB9 ERGL---PG---------EVLGAQ-------------------P------GPRGDAGVPG :::: :: :. : . : ::.::.: : CCDS27 ERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQG 1930 1940 1950 1960 1970 1980 800 810 820 830 840 pF1KB9 QPGLKG---LPGDRGPPGFRGSQGMPGMPGLK-GQPGLPGPSGQPGLYGPPGLHGFPGAP :: .: .::.:: : ::. : : ::: :. : ::::: : : ::. :.:: CCDS27 PPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRA 1990 2000 2010 2020 2030 2040 850 860 870 880 890 pF1KB9 GQEGPLGLPGIPGREGLPGDRGD------PGDTGAPGPVGMKG--LSGDRGDAGFTGEQG : : : :: :..: :.::. :: :.::: : : .: :. :..:::: CCDS27 GGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQG 2050 2060 2070 2080 2090 2100 900 910 920 930 940 950 pF1KB9 HPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGR---PGFPGSKGEAGFFGIPG :: : :: : : : ::::: ::. : .: :: .:. ::.:: .: :: : :: CCDS27 PPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPG 2110 2120 2130 2140 2150 2160 960 970 980 990 1000 1010 pF1KB9 LKGLAGEPGFKGSRGDPGPPGPPPVILP----GMKDIKGEKGDEGPMGLKGYLGAKGIQG :.: : :: :..::::::: : . : : . .::: :. :: : .: : : : CCDS27 LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVG 2170 2180 2190 2200 2210 2220 1020 1030 1040 1050 pF1KB9 MPGIPGLSGI------PGLPGR---------PGH--IKGVKGDIGVPGIPGLPGFPGVAG .:: :: ::. :::::. ::. .: :: : ::.:: ::.:: .: CCDS27 LPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVG 2230 2240 2250 2260 2270 2280 1060 1070 1080 1090 1100 pF1KB9 P---PGITGFPG-----FIGSRGDKGAPGR-AG-LYGEIGATGDFGDIGDTINLPGRPGL : :: :: :: . :..:.::::: :: : :: :: :: : ::: : CCDS27 PKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRG-------LPGPRGE 2290 2300 2310 2320 2330 2340 1110 1120 1130 1140 1150 1160 pF1KB9 KGERGTTGIPGLKGFFGEKGTEGDIGF---PGI--TGVTGVQGPPGLKGQTGFPGLTGPP ::: : .: :: : :.::. : :: ::. : : ::::.::. :.::: : : CCDS27 KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAP 2350 2360 2370 2380 2390 2400 1170 1180 1190 1200 1210 pF1KB9 GSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDI----H : : :. : : :. : : :: : :: .:: : : :: : : ::.. . CCDS27 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2410 2420 2430 2440 2450 2460 1220 1230 1240 1250 1260 pF1KB9 GDPG--FPGPPGERGDPG--EANTLPG---PVGVPGQKGDQGAPGERGPPGSPGLQGFPG :::: .::: ::::.:: . :: : :. : :..: ::.: :: ::.: : CCDS27 GDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2470 2480 2490 2500 2510 2520 1270 1280 1290 1300 1310 pF1KB9 ----ITPPSNISGAPGDKGAPGIFGLKGYRGP------PGPPGSAALPGSKGDTGNPG-- : : . :: :: : : :: : .:: :: :: . ::.::..: :: CCDS27 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2530 2540 2550 2560 2570 2580 1320 1330 1340 1350 1360 pF1KB9 ---AP-GTPGTKGWAGDSGPQGRPGVFGLPGEKG------PRG---EQGFMGNTGPTGAV .: : ::. : :: : :. :: :. :::: ::: :.: : : : CCDS27 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEK 2590 2600 2610 2620 2630 2640 1370 1380 1390 1400 1410 1420 pF1KB9 GDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGP ::.: :: : ::. : : .: ::. : . . : .::.: :: : :: : :: CCDS27 GDKGEAGPPGRPGLAGHKGEMGEPGVPG-QSGAPGKEGLIGPKGDRGFDGQPGPKGDQGE 2650 2660 2670 2680 2690 1430 1440 1450 1460 1470 pF1KB9 PGE---PGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRP--GSPGLP :: ::. : :: .: .: .: . :: : .:: : :: :..: ::. :.::.: CCDS27 KGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVP 2700 2710 2720 2730 2740 2750 1480 1490 1500 1510 1520 1530 pF1KB9 GMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLA : :: CCDS27 GAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSY 2760 2770 2780 2790 2800 2810 >>CCDS42829.1 COL4A3 gene_id:1285|Hs108|chr2 (1670 aa) initn: 2009 init1: 927 opt: 3122 Z-score: 1335.1 bits: 260.1 E(32554): 4.8e-68 Smith-Waterman score: 4844; 47.0% identity (60.5% similar) in 1664 aa overlap (100-1710:88-1667) 70 80 90 100 110 120 pF1KB9 GYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPR : :: : :. :: :. :.:: ::. :: CCDS42 GSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPY 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 GRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEP : : ::.:..:..: : ::. :. : :: : ::::: : : : .:.:: : CCDS42 GLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDA-KGDPGLP 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 GLVGFQG---PPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVG : : :: ::: :: :: :: : : :: :: ::::..:.: .: : .: :: .: CCDS42 GAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTG 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 QPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGIS-LKGE-----EGIMGF ::: :. .. . .: . : . ::.::. :::: : : : :: .: : CCDS42 PPGP---PGTVIVTLTGPDNRTDLKGE-KGDKGAMGEPGPPGPSGLPGESYGSEKGAPGD 240 250 260 270 280 290 310 320 330 340 350 pF1KB9 PGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGL--PAYSPHPSLA :::.: :: .: : ::..: .: :. : : : ::. :: ::::. :. CCDS42 PGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQE 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 KGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIP :: .: :: :: .: : :: : ::.:: :: : : :: : :: : :: CCDS42 KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 ALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKG :. : :: : : :: :: :::::: : . :: : :.:: :::: : : :: CCDS42 AM--GTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 DAG----ECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDKGDPGQHGLPGFPGLKGV . : .: : .. ::::: : ::. : .: : ::. :.::. :::::::. CCDS42 EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGF--- 480 490 500 510 520 540 550 560 570 580 590 pF1KB9 PGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPG---LPGP :: : :: :: ::. : . : :: :::: ::..:. : : ::. : :: :::: CCDS42 PGAQGDPGLKGEKGE----TLQPE-GQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGP 530 540 550 560 570 580 600 610 620 630 640 pF1KB9 PGD----GIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFL :. : :: : :: :: ::. : : :::: : : .:. :. : :.:: : CCDS42 KGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYG-P--QGEPGLQGTQGVPGAP--- 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 GPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIAGPKGLPGLPGPPGPTGAKGLRGIP :::: :: :... .: : : :: : :: :: ::: : :. : CCDS42 GPPGEAGPRGELSVSTPV-------------P----GPPGPPGPPGHPGPQGPPGIPGSL 640 650 660 670 710 720 730 740 750 760 pF1KB9 GFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPP : : : ::: : :: : ::::::: :.:..: .:: :: .: :: : : CCDS42 GKCGDPGLPGPDGEPGIPGI-GFPGPPG---PKGDQG---FPGTKGS---LGCPGKMGEP 680 690 700 710 720 770 780 790 800 810 820 pF1KB9 GERGLPGEVLGAQPGPRGDAGV--PGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPG- : : :: :: .:. .: :: :: :.::.:: : .: :.::.::: : :: CCDS42 GLPGKPG-----LPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 730 740 750 760 770 780 830 840 850 860 870 880 pF1KB9 --LPGPSGQPGLYGPPGLHGFPG--APGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPV : :: :.:: :::: .: :: : .: ::::. : .: : :: : : :: CCDS42 EGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIP 790 800 810 820 830 840 890 900 910 920 930 pF1KB9 GM--KGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKG :. .:. :. :. :. :.::. : : .: : :: : :. : :: :: : : : CCDS42 GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPG 850 860 870 880 890 900 940 950 960 970 980 990 pF1KB9 RPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGP :: ::. :. : ::::.:: : :: :: .:: : ::: . . . :.::. : CCDS42 PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEI-----SHVIGDKGEPGL 910 920 930 940 950 1000 1010 1020 1030 1040 1050 pF1KB9 MGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPG :. : : :: .:.::.:::.:. :::: :. : .::.: : :: ::. :. : : CCDS42 KGFAGNPGEKGNRGVPGMPGLKGLKGLPG-PAGPPGPRGDLGSTGNPGEPGLRGIPGSMG 960 970 980 990 1000 1010 1060 1070 1080 1090 1100 1110 pF1KB9 ITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPG-RPGLKGERGTTGIPGL :.:: :.:: : ::::: : : : :: :. : ::: : : :.:: CCDS42 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPG- 1020 1030 1040 1050 1060 1070 1120 1130 1140 1150 1160 1170 pF1KB9 KGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGD . : .:..: :: : : :: : :. : ::: : :: .:.:: :. : : CCDS42 -----DMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGP 1080 1090 1100 1110 1120 1130 1180 1190 1200 1210 1220 1230 pF1KB9 DGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGF-PGPPGERGDPGEANT : : :::::::: : :..: : :.:: : .:. :. .::: ::.:: .. CCDS42 PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE--KGETGLLRAPPGPRGNPGAQGA 1140 1150 1160 1170 1180 1190 1240 1250 1260 1270 1280 1290 pF1KB9 -----LPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGL :: :.::.:: .: : ::: : :. : ::. : . : : :..: :: : CCDS42 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL-PGAIIPGQTGNRGPPGSRGS 1200 1210 1220 1230 1240 1300 1310 1320 1330 1340 1350 pF1KB9 KGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGE : :::::::: .. : ::: :. : :: : : ::: :: :: :. : :: ::::. CCDS42 PGAPGPPGPPGSHVI-GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGD 1250 1260 1270 1280 1290 1300 1360 1370 1380 1390 pF1KB9 QGFMG---------NTGPTGAVGDRGPKGPKGDPGFPGAPGT---VGAPGIAGIPQKIAV ::.: : : :..: :: :::: :: : ::: .. :: : : CCDS42 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT--- 1310 1320 1330 1340 1350 1360 1400 1410 1420 1430 1440 1450 pF1KB9 QPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIG :: : ::. :::: ::..:: :: :.:: : :: :: :. .:..: : CCDS42 -PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE---------KGNKGSKG 1370 1380 1390 1400 1410 1460 1470 1480 1490 1500 1510 pF1KB9 HQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKLWSGYSLLY . :: :..: :: :. : : :. .. :.....:::: : :: : :.::.:.:. CCDS42 EPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVPLYSGFSFLF 1420 1430 1440 1450 1460 1470 1520 1530 1540 1550 1560 1570 pF1KB9 FEGQEKAHNQDLGLAGSCLARFSTMPFLYCNPGDVCYYASRNDKSYWLSTTA--PLPMMP .:...::.:::: :::: ::.:::::.:: .::: .::::: :::::: : :. : : CCDS42 VQGNQRAHGQDLGTLGSCLQRFTTMPFLFCNVNDVCNFASRNDYSYWLSTPALMPMNMAP 1480 1490 1500 1510 1520 1530 1580 1590 1600 1610 1620 1630 pF1KB9 VAEDEIKPYISRCSVCEAPAIAIAVHSQDVSIPHCPAGWRSLWIGYSFLMHTAAGDEGGG .. ..::::::.:::.:::::::::: ..:: :: :: ::: :.::.: :.::.:: : CCDS42 ITGRALEPYISRCTVCEGPAIAIAVHSQTTDIPPCPHGWISLWKGFSFIMFTSAGSEGTG 1540 1550 1560 1570 1580 1590 1640 1650 1660 1670 1680 1690 pF1KB9 QSLVSPGSCLEDFRATPFIECNGGRGTCHYYANKYSFWLTTI-PEQSFQGSPSADTLKAG :.:.:::::::.:::.::.::.: ::::.::.:.:::::... ::. :. .: .:.::: CCDS42 QALASPGSCLEEFRASPFLECHG-RGTCNYYSNSYSFWLASLNPERMFR-KPIPSTVKAG 1600 1610 1620 1630 1640 1650 1700 1710 pF1KB9 LIRTHISRCQVCMKNL .. ::::::::: CCDS42 ELEKIISRCQVCMKKRH 1660 1670 1712 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:56:27 2016 done: Thu Nov 3 22:56:28 2016 Total Scan time: 6.720 Total Display time: 1.470 Function used was FASTA [36.3.4 Apr, 2011]