Result of FASTA (omim) for
pF1KB9023
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9023, 1375 aa
1>>>pF1KB9023 1375 - 1375 aa - 1375 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1200+/-0.000444; mu= 5.7317+/- 0.028
mean_var=235.2011+/-47.658, 0's: 0 Z-trim(118.8): 462 B-trim: 213 in 2/53
Lambda= 0.083629
statistics sampled from 31648 (32197) to 31648 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.378), width: 16
Scan time: 12.990
The best scores are: opt bits E(85289)
NP_031387 (OMIM: 605399) nidogen-2 precursor [Homo (1375) 9674 1181.6 0
XP_005267462 (OMIM: 605399) PREDICTED: nidogen-2 i (1402) 7325 898.2 0
XP_005267464 (OMIM: 605399) PREDICTED: nidogen-2 i (1327) 5992 737.4 1.7e-211
XP_005267463 (OMIM: 605399) PREDICTED: nidogen-2 i (1354) 3687 459.3 8.8e-128
XP_011542497 (OMIM: 131390) PREDICTED: nidogen-1 i (1205) 1362 178.7 2.2e-43
NP_002499 (OMIM: 131390) nidogen-1 precursor [Homo (1247) 1355 177.9 4.1e-43
XP_011540398 (OMIM: 602600,608446) PREDICTED: low- ( 762) 674 95.6 1.5e-18
XP_016857755 (OMIM: 602600,608446) PREDICTED: low- ( 842) 674 95.6 1.6e-18
XP_006710945 (OMIM: 602600,608446) PREDICTED: low- ( 901) 674 95.6 1.7e-18
XP_006710944 (OMIM: 602600,608446) PREDICTED: low- ( 917) 674 95.6 1.8e-18
XP_005271230 (OMIM: 602600,608446) PREDICTED: low- ( 976) 674 95.6 1.8e-18
XP_016873223 (OMIM: 212780,604270,614305,616304) P (1809) 652 93.2 1.9e-17
NP_002325 (OMIM: 212780,604270,614305,616304) low- (1905) 652 93.2 1.9e-17
XP_011518406 (OMIM: 212780,604270,614305,616304) P (1160) 594 86.1 1.7e-15
NP_002326 (OMIM: 133780,144750,166710,259770,60181 (1615) 596 86.4 1.8e-15
XP_005274051 (OMIM: 133780,144750,166710,259770,60 (1653) 596 86.4 1.9e-15
XP_016874793 (OMIM: 603507,610947,616724) PREDICTE (1345) 594 86.1 1.9e-15
NP_059992 (OMIM: 602600,608446) low-density lipopr ( 700) 583 84.6 2.9e-15
XP_005271232 (OMIM: 602600,608446) PREDICTED: low- ( 834) 583 84.6 3.3e-15
XP_011518405 (OMIM: 212780,604270,614305,616304) P (1637) 589 85.6 3.3e-15
XP_011543333 (OMIM: 133780,144750,166710,259770,60 (1600) 587 85.3 3.9e-15
XP_011543332 (OMIM: 133780,144750,166710,259770,60 (1624) 587 85.3 3.9e-15
XP_011543331 (OMIM: 133780,144750,166710,259770,60 (1662) 587 85.3 4e-15
NP_002327 (OMIM: 603507,610947,616724) low-density (1613) 576 84.0 9.8e-15
XP_006719141 (OMIM: 603507,610947,616724) PREDICTE (1613) 576 84.0 9.8e-15
XP_016874792 (OMIM: 107770) PREDICTED: prolow-dens (4561) 584 85.3 1.1e-14
XP_005271231 (OMIM: 602600,608446) PREDICTED: low- ( 847) 566 82.6 1.4e-14
NP_001018064 (OMIM: 602600,608446) low-density lip ( 904) 560 81.9 2.4e-14
NP_004622 (OMIM: 602600,608446) low-density lipopr ( 963) 560 81.9 2.5e-14
XP_011540396 (OMIM: 602600,608446) PREDICTED: low- ( 934) 558 81.6 2.9e-14
XP_016859830 (OMIM: 608766) PREDICTED: low-density (4469) 555 81.8 1.2e-13
NP_061027 (OMIM: 608766) low-density lipoprotein r (4599) 555 81.8 1.3e-13
XP_011540397 (OMIM: 602600,608446) PREDICTED: low- ( 804) 536 78.9 1.6e-13
NP_001018066 (OMIM: 192977,224050) very low-densit ( 845) 522 77.3 5.5e-13
NP_003374 (OMIM: 192977,224050) very low-density l ( 873) 522 77.3 5.6e-13
XP_016857754 (OMIM: 602600,608446) PREDICTED: low- ( 921) 522 77.3 5.9e-13
NP_001278831 (OMIM: 133780,144750,166710,259770,60 (1034) 523 77.4 5.9e-13
XP_016873224 (OMIM: 133780,144750,166710,259770,60 (1072) 523 77.5 6e-13
NP_001309155 (OMIM: 192977,224050) very low-densit ( 804) 519 76.9 6.8e-13
NP_001309154 (OMIM: 192977,224050) very low-densit ( 832) 519 76.9 7e-13
NP_150643 (OMIM: 602600,608446) low-density lipopr ( 793) 518 76.8 7.3e-13
XP_011526312 (OMIM: 143890,606945) PREDICTED: low- ( 834) 513 76.2 1.2e-12
NP_001182727 (OMIM: 143890,606945) low-density lip ( 858) 513 76.2 1.2e-12
NP_000518 (OMIM: 143890,606945) low-density lipopr ( 860) 513 76.2 1.2e-12
XP_016863342 (OMIM: 131530,611718) PREDICTED: pro- ( 934) 513 76.2 1.3e-12
XP_016863341 (OMIM: 131530,611718) PREDICTED: pro- (1010) 513 76.2 1.3e-12
XP_016863340 (OMIM: 131530,611718) PREDICTED: pro- (1060) 513 76.3 1.4e-12
NP_002323 (OMIM: 107770) prolow-density lipoprotei (4544) 526 78.3 1.4e-12
XP_016863339 (OMIM: 131530,611718) PREDICTED: pro- (1141) 513 76.3 1.5e-12
XP_016863338 (OMIM: 131530,611718) PREDICTED: pro- (1142) 513 76.3 1.5e-12
>>NP_031387 (OMIM: 605399) nidogen-2 precursor [Homo sap (1375 aa)
initn: 9674 init1: 9674 opt: 9674 Z-score: 6318.8 bits: 1181.6 E(85289): 0
Smith-Waterman score: 9674; 99.6% identity (99.6% similar) in 1375 aa overlap (1-1375:1-1375)
10 20 30 40 50 60
pF1KB9 MEGDRVAGRPVLSSLPVLLLLQLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_031 MEGDRVAGRPVLSSLPVLLLLPLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEESST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEESST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 LDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENGSI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 QPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASDHTTPLSRGTYEVGLEDNIGSNTEVFTY
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_031 QPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASGHTTPLSRGTYEVGLEDNIGSNTEVFTY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 NAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGASHRVNGKVSGHL
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_031 NAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 HVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 HVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 SENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_031 SENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVSANFT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 AHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRHPSFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 AHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRHPSFPT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 TQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGT
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
NP_031 TQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPGNPCYDGSHMCDTTARCHPGT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 GVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 GVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 TCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDECSENR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 TCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDECSENR
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 CHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQAQYAYPGARFHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 CHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQAQYAYPGARFHI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB9 RWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 RWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB9 TPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 TPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB9 GSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 GSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTM
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB9 YWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 YWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB9 DGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 DGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370
pF1KB9 IVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_031 IVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
1330 1340 1350 1360 1370
>>XP_005267462 (OMIM: 605399) PREDICTED: nidogen-2 isofo (1402 aa)
initn: 7325 init1: 7325 opt: 7325 Z-score: 4787.0 bits: 898.2 E(85289): 0
Smith-Waterman score: 9610; 97.7% identity (97.7% similar) in 1402 aa overlap (1-1375:1-1402)
10 20 30 40 50 60
pF1KB9 MEGDRVAGRPVLSSLPVLLLLQLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_005 MEGDRVAGRPVLSSLPVLLLLPLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLE----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEGRIS
310 320 330 340 350 360
360 370 380 390
pF1KB9 -----------------------ESSTLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRS
:::::::::::::::::::::::::::::::::::::
XP_005 PPDSDLSSPLHPTPTYWPFYPETESSTLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB9 PAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB9 HTTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQ
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB9 SKFYGNGKHCLPEGASHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIP
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB9 QPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB9 EGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYSDSTVTSTSSRDYSLTFGAIN
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_005 EGLDPENYLSIKTNIQGQVPYVSANFTAHISPYKELYHYSDSTVTSTSSRDYSLTFGAIN
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB9 QTWSYRIHQNITYQVCRHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTWSYRIHQNITYQVCRHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPVKE
730 740 750 760 770 780
760 770 780 790 800 810
pF1KB9 DSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCG
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDPTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCG
790 800 810 820 830 840
820 830 840 850 860 870
pF1KB9 PNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGS
850 860 870 880 890 900
880 890 900 910 920 930
pF1KB9 TFSCACLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFSCACLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDS
910 920 930 940 950 960
940 950 960 970 980 990
pF1KB9 TSSLTPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSLTPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPG
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KB9 TQTPPGSTPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQTPPGSTPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQ
1030 1040 1050 1060 1070 1080
1060 1070 1080 1090 1100 1110
pF1KB9 CHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYT
1090 1100 1110 1120 1130 1140
1120 1130 1140 1150 1160 1170
pF1KB9 QGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLEL
1150 1160 1170 1180 1190 1200
1180 1190 1200 1210 1220 1230
pF1KB9 GAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRA
1210 1220 1230 1240 1250 1260
1240 1250 1260 1270 1280 1290
pF1KB9 IAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADA
1270 1280 1290 1300 1310 1320
1300 1310 1320 1330 1340 1350
pF1KB9 GTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYL
1330 1340 1350 1360 1370 1380
1360 1370
pF1KB9 PEQRSHLYGITAVYPYCPTGRK
::::::::::::::::::::::
XP_005 PEQRSHLYGITAVYPYCPTGRK
1390 1400
>>XP_005267464 (OMIM: 605399) PREDICTED: nidogen-2 isofo (1327 aa)
initn: 6217 init1: 5798 opt: 5992 Z-score: 3918.2 bits: 737.4 E(85289): 1.7e-211
Smith-Waterman score: 9184; 96.1% identity (96.1% similar) in 1375 aa overlap (1-1375:1-1327)
10 20 30 40 50 60
pF1KB9 MEGDRVAGRPVLSSLPVLLLLQLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_005 MEGDRVAGRPVLSSLPVLLLLPLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEESST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEESST
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 LDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENGSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENGSI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 QPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASDHTTPLSRGTYEVGLEDNIGSNTEVFTY
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
XP_005 QPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASGHTTPLSRGTYEVGLEDNIGSNTEVFTY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 NAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGASHRVNGKVSGHL
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
XP_005 NAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGAPHRVNGKVSGHL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 HVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFALEKPG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 SENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVPANFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::::
XP_005 SENGFSLAGAAFTHDMEVTFYPGEETVRITQTAEGLDPENYLSIKTNIQGQVPYVSANFT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB9 AHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRHPSFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHISPYKELYHYSDSTVTSTSSRDYSLTFGAINQTWSYRIHQNITYQVCRHAPRHPSFPT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB9 TQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGT
::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_005 TQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPGNPCYDGSHMCDTTARCHPGT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB9 GVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCECRSGYEFADDRH
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB9 TCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQCTDVDECSENR
::: ::::::::
XP_005 TCIY------------------------------------------------VDECSENR
850
910 920 930 940 950 960
pF1KB9 CHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQAQYAYPGARFHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQAQYAYPGARFHI
860 870 880 890 900 910
970 980 990 1000 1010 1020
pF1KB9 PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSPEPTQRPPTICE
920 930 940 950 960 970
1030 1040 1050 1060 1070 1080
pF1KB9 RWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGT
980 990 1000 1010 1020 1030
1090 1100 1110 1120 1130 1140
pF1KB9 TPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLH
1040 1050 1060 1070 1080 1090
1150 1160 1170 1180 1190 1200
pF1KB9 GSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISPEGLAIDHIRRTM
1100 1110 1120 1130 1140 1150
1210 1220 1230 1240 1250 1260
pF1KB9 YWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSL
1160 1170 1180 1190 1200 1210
1270 1280 1290 1300 1310 1320
pF1KB9 DGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGRRVIQNNLKYPFS
1220 1230 1240 1250 1260 1270
1330 1340 1350 1360 1370
pF1KB9 IVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
1280 1290 1300 1310 1320
>>XP_005267463 (OMIM: 605399) PREDICTED: nidogen-2 isofo (1354 aa)
initn: 5868 init1: 3527 opt: 3687 Z-score: 2415.1 bits: 459.3 E(85289): 8.8e-128
Smith-Waterman score: 9120; 94.2% identity (94.2% similar) in 1402 aa overlap (1-1375:1-1354)
10 20 30 40 50 60
pF1KB9 MEGDRVAGRPVLSSLPVLLLLQLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_005 MEGDRVAGRPVLSSLPVLLLLPLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LANPLHFYEARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGRG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGELN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDLKSEGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGRSF
250 260 270 280 290 300
310 320 330 340 350
pF1KB9 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLE----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEGRIS
310 320 330 340 350 360
360 370 380 390
pF1KB9 -----------------------ESSTLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRS
:::::::::::::::::::::::::::::::::::::
XP_005 PPDSDLSSPLHPTPTYWPFYPETESSTLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB9 PAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PAPPEVDRDSLAPSWETPPPYPENGSIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASG
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB9 HTTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HTTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQ
490 500 510 520 530 540
520 530 540 550 560 570
pF1KB9 SKFYGNGKHCLPEGASHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIP
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKFYGNGKHCLPEGAPHRVNGKVSGHLHVGHTPVHFTDVDLHAYIVGNDGRAYTAISHIP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KB9 QPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPAAQALLPLTPIGGLFGWLFALEKPGSENGFSLAGAAFTHDMEVTFYPGEETVRITQTA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KB9 EGLDPENYLSIKTNIQGQVPYVPANFTAHISPYKELYHYSDSTVTSTSSRDYSLTFGAIN
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_005 EGLDPENYLSIKTNIQGQVPYVSANFTAHISPYKELYHYSDSTVTSTSSRDYSLTFGAIN
670 680 690 700 710 720
700 710 720 730 740 750
pF1KB9 QTWSYRIHQNITYQVCRHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPVKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTWSYRIHQNITYQVCRHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPVKE
730 740 750 760 770 780
760 770 780 790 800 810
pF1KB9 DSDPTPVNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCG
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSDPTPGNPCYDGSHMCDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCG
790 800 810 820 830 840
820 830 840 850 860 870
pF1KB9 PNSVCINLPGSYRCECRSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGS
::::::::::::::::::::::::::::::
XP_005 PNSVCINLPGSYRCECRSGYEFADDRHTCIY-----------------------------
850 860 870
880 890 900 910 920 930
pF1KB9 TFSCACLPGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDS
:::::::::::::::::::::::::::::::::::::::::
XP_005 -------------------VDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDS
880 890 900 910
940 950 960 970 980 990
pF1KB9 TSSLTPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSSLTPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPG
920 930 940 950 960 970
1000 1010 1020 1030 1040 1050
pF1KB9 TQTPPGSTPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQTPPGSTPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQ
980 990 1000 1010 1020 1030
1060 1070 1080 1090 1100 1110
pF1KB9 CHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDVTPPSVGTFLLYT
1040 1050 1060 1070 1080 1090
1120 1130 1140 1150 1160 1170
pF1KB9 QGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLEL
1100 1110 1120 1130 1140 1150
1180 1190 1200 1210 1220 1230
pF1KB9 GAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAEPETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRA
1160 1170 1180 1190 1200 1210
1240 1250 1260 1270 1280 1290
pF1KB9 IAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADA
1220 1230 1240 1250 1260 1270
1300 1310 1320 1330 1340 1350
pF1KB9 GTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTKKLECTLPDGTGRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYL
1280 1290 1300 1310 1320 1330
1360 1370
pF1KB9 PEQRSHLYGITAVYPYCPTGRK
::::::::::::::::::::::
XP_005 PEQRSHLYGITAVYPYCPTGRK
1340 1350
>>XP_011542497 (OMIM: 131390) PREDICTED: nidogen-1 isofo (1205 aa)
initn: 2839 init1: 1000 opt: 1362 Z-score: 899.8 bits: 178.7 E(85289): 2.2e-43
Smith-Waterman score: 3269; 40.6% identity (63.8% similar) in 1368 aa overlap (18-1373:16-1166)
10 20 30 40 50 60
pF1KB9 MEGDRVAGRPVLSSLPVLLLLQLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
::: :: .. : .:::: : . :: :..::: : ...
XP_011 MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDFVSPALE
10 20 30 40 50
70 80 90 100 110
pF1KB9 LANPLHFYE-ARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGR
:.. :.::. . .. .:: :::::.:.. : . .. :: : :.::::::.::. :
XP_011 LSGALRFYDRSDIDAVYVTTNGIIATSEPPAKESHPGL-FPPTFGAVAPFLADLDTTDGL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 GRVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGEL
:.: :::: ::.. ::. :. :::. . : :. : ..:::.:. :. .: .:.
XP_011 GKVYYREDLSPSITQRAAECVHRGFPEIS-FQPSSAVVVTWESVAPYQGPSRDPDQKGKR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 NTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDL-KSE
:::::::::. :.:::.:::: .:::: : :. : :.:: :.: .: . : ::.
XP_011 NTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKENN---QVPAVVAFSQGSVGFLWKSN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 GPYFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGR
: : ... ..::.:: . :: : :::.:.::: . ..: :: .: ::
XP_011 GAYNIFANDRESVENLAKSSNSGQQGVWVFEIGSPATTNGVVPA----------DVILG-
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 SFSHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEES
.::. .: : :. .: :..
XP_011 ------------TEDGAEYDD---EDEDY---------------DLAT------------
290 300
360 370 380 390 400 410
pF1KB9 STLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENG
:. : : .:: . :.. . : . .: :. :: .: . .
XP_011 ------TRLG--LEDVG-------TTPFSYKALRRGG---ADTYSV-PSVLSPR---RAA
310 320 330
420 430 440 450 460 470
pF1KB9 SIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASDHTTPLSRGTYEVGLEDNIGSNTEVF
. .: :: :.: ::. . .: . . .: :.. . ::
XP_011 TERPL---GP-PTERT------------RSFQLAVET--FHQQHPQVIDVDEVEETGVVF
340 350 360 370 380
480 490 500 510 520 530
pF1KB9 TYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGASHRVNGKVSG
.::. ...:: .:..::: :: : :::::::: : . . :::..:. ::. .::::::.:
XP_011 SYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKG
390 400 410 420 430 440
540 550 560 570 580 590
pF1KB9 HLHVGHT--PVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFAL
.. :: . :. : ..:::.:.: : ::.::::: ::. .. .::::.:.::..::.::.
XP_011 RIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAV
450 460 470 480 490 500
600 610 620 630 640 650
pF1KB9 EKPGSENGFSLAGAAFTHDMEVTF--YPGEETVRITQTAEGLDPENYLSIKTNIQGQVPY
:. : .::::..:. ::.. :::: .::. ... : :.: ...:.: :...:.::
XP_011 EQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIK--QRFSGIDEHGHLTIDTELEGRVPQ
510 520 530 540 550
660 670 680 690 700
pF1KB9 VPANFTAHISPYKELYHYSDSTVTSTSSRDYSLTF----GAI-NQTWSYRIHQNITYQVC
.: . ..:: :: :::::: :..::.:.:.:..: :: .. ..:. .:.::.: :
XP_011 IPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSRIYTYQWRQTITFQEC
560 570 580 590 600 610
710 720 730 740 750 760
pF1KB9 RHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHM
: .:..:.::::.:: ::.:::.::..::.:..:.::::.: : . :::: :.:
XP_011 VHDDSRPALPSTQQLSVDSVFVLYNQEEKILRYALSNSIGPVREGSPDALQNPCYIGTHG
620 630 640 650 660 670
770 780 790 800 810 820
pF1KB9 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCEC
:::.: :.:: ...::::. :..::::.:
XP_011 CDTNAACRPGPRTQFTCECSIGFRGDGRTC------------------------------
680 690 700
830 840 850 860 870 880
pF1KB9 RSGYEFADDRHTCILITPPANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDGHQ
: .:.: : : :: : :.: .:.:.. :::...:.::::..:::.
XP_011 ---YAVVDQR--------PINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDGQA
710 720 730 740 750
890 900 910 920 930 940
pF1KB9 CTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHAQA
: :::::. .:::: : ::::::::.:.:.::: ::::.:.: . . : :.....:
XP_011 CQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEK-TRCQHEREHIL-
760 770 780 790 800 810
950 960 970 980 990 1000
pF1KB9 QYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGPSP
:..: .:: . : :::
XP_011 --------------------------GAAG---ATDP---QRP---IPPG----------
820 830
1010 1020 1030 1040 1050 1060
pF1KB9 EPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGR
.::.:: ::. : ::::.. .:::::.:::
XP_011 ----------------------------LFVPECDAHGHYAPTQCHGSTGYCWCVDRDGR
840 850 860
1070 1080 1090 1100 1110 1120
pF1KB9 EVQGTRSQPGTTPACIPTVAPPMVRPTPRPD-VTPPSVGTFLLYTQGQQIGYLPLNGTRL
::.:::..:: :: :. :::::. . : : : :: ::..: .: :::.:. .
XP_011 EVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGNTM
870 880 890 900 910 920
1130 1140 1150 1160 1170 1180
pF1KB9 QKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLISP
.: ::..: . ...:.:. .:: ..::::::.. .:.::.:. :.:: ::. . : ::
XP_011 RKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLH-GGEPTTIIRQDLGSP
930 940 950 960 970 980
1190 1200 1210 1220 1230 1240
pF1KB9 EGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWTDW
::.:.::. :...:::: ::.:: : :::..:.::: :::::::.:..: .:::::::::
XP_011 EGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWTDW
990 1000 1010 1020 1030 1040
1250 1260 1270 1280 1290 1300
pF1KB9 NREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGTGR
::. :::::: .:: :::::.. :.::::::::: ::. :::.::::.. :: :. .:
XP_011 NRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQPSR
1050 1060 1070 1080 1090 1100
1310 1320 1330 1340 1350 1360
pF1KB9 RVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAVYP
: ..:.:::...::. ..: :::. ..::... .. :: . :.....:::::..
XP_011 RKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPHKQTRLYGITTALS
1110 1120 1130 1140 1150 1160
1370
pF1KB9 YCPTGRK
:: :
XP_011 QCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK
1170 1180 1190 1200
>>NP_002499 (OMIM: 131390) nidogen-1 precursor [Homo sap (1247 aa)
initn: 3383 init1: 1000 opt: 1355 Z-score: 895.0 bits: 177.9 E(85289): 4.1e-43
Smith-Waterman score: 3496; 41.7% identity (65.7% similar) in 1370 aa overlap (18-1373:16-1208)
10 20 30 40 50 60
pF1KB9 MEGDRVAGRPVLSSLPVLLLLQLLMLRAAALHPDELFPHGESWGDQLLQEGDDESSAVVK
::: :: .. : .:::: : . :: :..::: : ...
NP_002 MLASSSRIRAAWTRALLLPLLLAGPVGCLSRQELFPFGPGQGDLELEDGDDFVSPALE
10 20 30 40 50
70 80 90 100 110
pF1KB9 LANPLHFYE-ARFSNLYVGTNGIISTQDFPRETQYVDYDFPTDFPAIAPFLADIDTSHGR
:.. :.::. . .. .:: :::::.:.. : . .. :: : :.::::::.::. :
NP_002 LSGALRFYDRSDIDAVYVTTNGIIATSEPPAKESHPGL-FPPTFGAVAPFLADLDTTDGL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 GRVLYREDTSPAVLGLAARYVRAGFPRSARFTPTHAFLATWEQVGAYEEVKRGALPSGEL
:.: :::: ::.. ::. :. :::. . : :. : ..:::.:. :. .: .:.
NP_002 GKVYYREDLSPSITQRAAECVHRGFPEIS-FQPSSAVVVTWESVAPYQGPSRDPDQKGKR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB9 NTFQAVLASDGSDSYALFLYPANGLQFLGTRPKESYNVQLQLPARVGFCRGEADDL-KSE
:::::::::. :.:::.:::: .:::: : :. : :.:: :.: .: . : ::.
NP_002 NTFQAVLASSDSSSYAIFLYPEDGLQFHTTFSKKENN---QVPAVVAFSQGSVGFLWKSN
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB9 GPYFSLTSTEQSVKNLYQLSNLGIPGVWAFHIGSTSPLDNVRPAAVGDLSAAHSSVPLGR
: : ... ..::.:: . :: : :::.:.::: . ..: :: .: ::
NP_002 GAYNIFANDRESVENLAKSSNSGQQGVWVFEIGSPATTNGVVPA----------DVILG-
240 250 260 270 280
300 310 320 330 340 350
pF1KB9 SFSHATALESDYNEDNLDYYDVNEEEAEYLPGEPEEALNGHSSIDVSFQSKVDTKPLEES
.::. .: : :. .: :..
NP_002 ------------TEDGAEYDD---EDEDY---------------DLAT------------
290 300
360 370 380 390 400 410
pF1KB9 STLDPHTKEGTSLGEVGGPDLKGQVEPWDERETRSPAPPEVDRDSLAPSWETPPPYPENG
:. : : .:: . :.. . : . .: :. :: .: . .
NP_002 ------TRLG--LEDVG-------TTPFSYKALRRGG---ADTYSV-PSVLSPR---RAA
310 320 330
420 430 440 450 460 470
pF1KB9 SIQPYPDGGPVPSEMDVPPAHPEEEIVLRSYPASDHTTPLSRGTYEVGLEDNIGSNTEVF
. .: :: :.: ::. . .: . . .: :.. . ::
NP_002 TERPL---GP-PTERT------------RSFQLAVET--FHQQHPQVIDVDEVEETGVVF
340 350 360 370 380
480 490 500 510 520 530
pF1KB9 TYNAANKETCEHNHRQCSRHAFCTDYATGFCCHCQSKFYGNGKHCLPEGASHRVNGKVSG
.::. ...:: .:..::: :: : :::::::: : . . :::..:. ::. .::::::.:
NP_002 SYNTDSRQTCANNRHQCSVHAECRDYATGFCCSCVAGYTGNGRQCVAEGSPQRVNGKVKG
390 400 410 420 430 440
540 550 560 570 580 590
pF1KB9 HLHVGHT--PVHFTDVDLHAYIVGNDGRAYTAISHIPQPAAQALLPLTPIGGLFGWLFAL
.. :: . :. : ..:::.:.: : ::.::::: ::. .. .::::.:.::..::.::.
NP_002 RIFVGSSQVPIVFENTDLHSYVVMNHGRSYTAISTIPETVGYSLLPLAPVGGIIGWMFAV
450 460 470 480 490 500
600 610 620 630 640 650
pF1KB9 EKPGSENGFSLAGAAFTHDMEVTF--YPGEETVRITQTAEGLDPENYLSIKTNIQGQVPY
:. : .::::..:. ::.. :::: .::. ... : :.: ...:.: :...:.::
NP_002 EQDGFKNGFSITGGEFTRQAEVTFVGHPGNLVIK--QRFSGIDEHGHLTIDTELEGRVPQ
510 520 530 540 550
660 670 680 690 700
pF1KB9 VPANFTAHISPYKELYHYSDSTVTSTSSRDYSLTF----GAI-NQTWSYRIHQNITYQVC
.: . ..:: :: :::::: :..::.:.:.:..: :: .. ..:. .:.::.: :
NP_002 IPFGSSVHIEPYTELYHYSTSVITSSSTREYTVTEPERDGASPSRIYTYQWRQTITFQEC
560 570 580 590 600 610
710 720 730 740 750 760
pF1KB9 RHAPRHPSFPTTQQLNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHM
: .:..:.::::.:: ::.:::.::..::.:..:.::::.: : . :::: :.:
NP_002 VHDDSRPALPSTQQLSVDSVFVLYNQEEKILRYALSNSIGPVREGSPDALQNPCYIGTHG
620 630 640 650 660 670
770 780 790 800 810 820
pF1KB9 CDTTARCHPGTGVDYTCECASGYQGDGRNCVDENECATGFHRCGPNSVCINLPGSYRCEC
:::.: :.:: ...::::. :..::::.: : .::. :: ...: : ::..::::
NP_002 CDTNAACRPGPRTQFTCECSIGFRGDGRTCYDIDECSEQPSVCGSHTICNNHPGTFRCEC
680 690 700 710 720 730
830 840 850 860 870 880
pF1KB9 RSGYEFADDRHTCILITP--PANPCEDGSHTCAPAGQARCVHHGGSTFSCACLPGYAGDG
::.:.:. ::. .. : : :: : :.: .:.:.. :::...:.::::..:::
NP_002 VEGYQFSDE-GTCVAVVDQRPINYCETGLHNCDIPQRAQCIYTGGSSYTCSCLPGFSGDG
740 750 760 770 780 790
890 900 910 920 930 940
pF1KB9 HQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPCEQQQRHA
. : :::::. .:::: : ::::::::.:.:.::: ::::.:.: . . : :.....:
NP_002 QACQDVDECQPSRCHPDAFCYNTPGSFTCQCKPGYQGDGFRCVPGEVEK-TRCQHEREHI
800 810 820 830 840 850
950 960 970 980 990 1000
pF1KB9 QAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTPPGSTPPHCGP
:..: .:: . : :::
NP_002 L---------------------------GAAG---ATDP---QRP---IPPG--------
860 870
1010 1020 1030 1040 1050 1060
pF1KB9 SPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKD
.::.:: ::. : ::::.. .:::::.:
NP_002 ------------------------------LFVPECDAHGHYAPTQCHGSTGYCWCVDRD
880 890 900
1070 1080 1090 1100 1110 1120
pF1KB9 GREVQGTRSQPGTTPACIPTVAPPMVRPTPRPD-VTPPSVGTFLLYTQGQQIGYLPLNGT
::::.:::..:: :: :. :::::. . : : : :: ::..: .: :::.:.
NP_002 GREVEGTRTRPGMTPPCLSTVAPPIHQGPAVPTAVIPLPPGTHLLFAQTGKIERLPLEGN
910 920 930 940 950 960
1130 1140 1150 1160 1170 1180
pF1KB9 RLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTISRAGLELGAEPETIVNSGLI
..: ::..: . ...:.:. .:: ..::::::.. .:.::.:. :.:: ::. . :
NP_002 TMRKTEAKAFLHVPAKVIIGLAFDCVDKMVYWTDITEPSIGRASLH-GGEPTTIIRQDLG
970 980 990 1000 1010 1020
1190 1200 1210 1220 1230 1240
pF1KB9 SPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLFYTDLVNPRAIAVDPIRGNLYWT
::::.:.::. :...:::: ::.:: : :::..:.::: :::::::.:..: .:::::::
NP_002 SPEGIAVDHLGRNIFWTDSNLDRIEVAKLDGTQRRVLFETDLVNPRGIVTDSVRGNLYWT
1030 1040 1050 1060 1070 1080
1250 1260 1270 1280 1290 1300
pF1KB9 DWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPFSKLLCWADAGTKKLECTLPDGT
::::. :::::: .:: :::::.. :.::::::::: ::. :::.::::.. :: :.
NP_002 DWNRDNPKIETSYMDGTNRRILVQDDLGLPNGLTFDAFSSQLCWVDAGTNRAECLNPSQP
1090 1100 1110 1120 1130 1140
1310 1320 1330 1340 1350 1360
pF1KB9 GRRVIQNNLKYPFSIVSYADHFYHTDWRRDGVVSVNKHSGQFTDEYLPEQRSHLYGITAV
.:: ..:.:::...::. ..: :::. ..::... .. :: . :.....:::::..
NP_002 SRRKALEGLQYPFAVTSYGKNLYFTDWKMNSVVALDLAISKETDAFQPHKQTRLYGITTA
1150 1160 1170 1180 1190 1200
1370
pF1KB9 YPYCPTGRK
:: :
NP_002 LSQCPQGHNYCSVNNGGCTHLCLATPGSRTCRCPDNTLGVDCIEQK
1210 1220 1230 1240
>>XP_011540398 (OMIM: 602600,608446) PREDICTED: low-dens (762 aa)
initn: 486 init1: 258 opt: 674 Z-score: 453.9 bits: 95.6 E(85289): 1.5e-18
Smith-Waterman score: 679; 27.4% identity (51.5% similar) in 635 aa overlap (754-1346:77-672)
730 740 750 760 770 780
pF1KB9 LNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVD
: : : . : :.. ::. : :
XP_011 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCD
50 60 70 80 90 100
790 800 810 820 830
pF1KB9 YTCECASGYQGDGRNCVDENECATGFHRCGPNS-VCINLPGSYRCE----CRSG------
:: .: . . .:. . : . :::.: :. :.:.::. :..:
XP_011 GEEECPDGSDESEATCTKQV-CPAEKLSCGPTSHKCV--PASWRCDGEKDCEGGADEAGC
110 120 130 140 150 160
840 850 860 870 880
pF1KB9 ------YEFADDRHTC---ILITPPANPCEDGSHT--CA-PAGQARCVHHGGSTFSCACL
.:: ..: ... . : ::: :: :: : . ::. . ::.
XP_011 ATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDG-GGACI
170 180 190 200 210 220
890 900 910 920 930 940
pF1KB9 PGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPC
: . : .: :.: :: . :: :: . : .:.: :
XP_011 P----ERWVCDRQFDC-EDRSDEAAELCGRPG-------PGATSAPAAC---ATASQFAC
230 240 250 260
950 960 970 980 990
pF1KB9 EQQQRHAQAQYAYPGARFHIPQCDEQGNFLPL-QCHGSTGFCW---CVDPDGHEVPGTQT
.. . .. . : : . :: :: :.:. : :: : .
XP_011 RSGE-CVHLGWRCDGDRDCKDKSDEADC--PLGTCRGDEFQCGDGTCVLAIKHCNQEQDC
270 280 290 300 310 320
1000 1010 1020 1030 1040
pF1KB9 PPGSTPPHCGPSPEPTQRPPT-ICERWR----ENLLEHYGGTPR---DDQYVPQCDDLGH
: :: : : ::: . .: : .. :.. :: . : . .: .
XP_011 PDGSDEAGC------LQVPPTFLGNRRRPRGLNECLHNNGGCSHICTDLKIGFECTCPAG
330 340 350 360 370
1050 1060 1070 1080 1090 1100
pF1KB9 FIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDV-TPPSVG
: :. . .:. : : :. . . : : .. . . . ::
XP_011 FQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPS--
380 390 400 410 420 430
1110 1120 1130 1140 1150 1160
pF1KB9 TFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTIS
:..:. ... . : .... .. . :.. .:..: . .:: :.. : :
XP_011 --LIFTNRHEVRRIDL----VKRNYSRLIPMLKN--VVALDVEVATNRIYWCDLSYRKIY
440 450 460 470 480
1170 1180 1190 1200 1210 1220
pF1KB9 RAGLELGAEP---ETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLF
: .. ...: :.... : ::::::.: ... .::::: : : .::..:..::
XP_011 SAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLF
490 500 510 520 530 540
1230 1240 1250 1260 1270 1280
pF1KB9 YTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPF
.: .::::::::.:: .::.::. .: ::: :.:.: .:. :.. .: :::.:.: .
XP_011 SRNLSEPRAIAVDPLRGFMYWSDWGDQA-KIEKSGLNGVDRQTLVSDNIEWPNGITLDLL
550 560 570 580 590 600
1290 1300 1310 1320 1330 1340
pF1KB9 SKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVSYADHFYHTDWRRDGVVSV
:. : :.:. ..: .: .:... .. :..::.:. . :. . :: . ... :.
XP_011 SQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSA
610 620 630 640 650 660
1350 1360 1370
pF1KB9 NKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
:. .:
XP_011 NRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHS
670 680 690 700 710 720
>>XP_016857755 (OMIM: 602600,608446) PREDICTED: low-dens (842 aa)
initn: 486 init1: 258 opt: 674 Z-score: 453.3 bits: 95.6 E(85289): 1.6e-18
Smith-Waterman score: 679; 27.4% identity (51.5% similar) in 635 aa overlap (754-1346:77-672)
730 740 750 760 770 780
pF1KB9 LNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVD
: : : . : :.. ::. : :
XP_016 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCD
50 60 70 80 90 100
790 800 810 820 830
pF1KB9 YTCECASGYQGDGRNCVDENECATGFHRCGPNS-VCINLPGSYRCE----CRSG------
:: .: . . .:. . : . :::.: :. :.:.::. :..:
XP_016 GEEECPDGSDESEATCTKQV-CPAEKLSCGPTSHKCV--PASWRCDGEKDCEGGADEAGC
110 120 130 140 150 160
840 850 860 870 880
pF1KB9 ------YEFADDRHTC---ILITPPANPCEDGSHT--CA-PAGQARCVHHGGSTFSCACL
.:: ..: ... . : ::: :: :: : . ::. . ::.
XP_016 ATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDG-GGACI
170 180 190 200 210 220
890 900 910 920 930 940
pF1KB9 PGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPC
: . : .: :.: :: . :: :: . : .:.: :
XP_016 P----ERWVCDRQFDC-EDRSDEAAELCGRPG-------PGATSAPAAC---ATASQFAC
230 240 250 260
950 960 970 980 990
pF1KB9 EQQQRHAQAQYAYPGARFHIPQCDEQGNFLPL-QCHGSTGFCW---CVDPDGHEVPGTQT
.. . .. . : : . :: :: :.:. : :: : .
XP_016 RSGE-CVHLGWRCDGDRDCKDKSDEADC--PLGTCRGDEFQCGDGTCVLAIKHCNQEQDC
270 280 290 300 310 320
1000 1010 1020 1030 1040
pF1KB9 PPGSTPPHCGPSPEPTQRPPT-ICERWR----ENLLEHYGGTPR---DDQYVPQCDDLGH
: :: : : ::: . .: : .. :.. :: . : . .: .
XP_016 PDGSDEAGC------LQVPPTFLGNRRRPRGLNECLHNNGGCSHICTDLKIGFECTCPAG
330 340 350 360 370
1050 1060 1070 1080 1090 1100
pF1KB9 FIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDV-TPPSVG
: :. . .:. : : :. . . : : .. . . . ::
XP_016 FQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPS--
380 390 400 410 420 430
1110 1120 1130 1140 1150 1160
pF1KB9 TFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTIS
:..:. ... . : .... .. . :.. .:..: . .:: :.. : :
XP_016 --LIFTNRHEVRRIDL----VKRNYSRLIPMLKN--VVALDVEVATNRIYWCDLSYRKIY
440 450 460 470 480
1170 1180 1190 1200 1210 1220
pF1KB9 RAGLELGAEP---ETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLF
: .. ...: :.... : ::::::.: ... .::::: : : .::..:..::
XP_016 SAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLF
490 500 510 520 530 540
1230 1240 1250 1260 1270 1280
pF1KB9 YTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPF
.: .::::::::.:: .::.::. .: ::: :.:.: .:. :.. .: :::.:.: .
XP_016 SRNLSEPRAIAVDPLRGFMYWSDWGDQA-KIEKSGLNGVDRQTLVSDNIEWPNGITLDLL
550 560 570 580 590 600
1290 1300 1310 1320 1330 1340
pF1KB9 SKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVSYADHFYHTDWRRDGVVSV
:. : :.:. ..: .: .:... .. :..::.:. . :. . :: . ... :.
XP_016 SQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSA
610 620 630 640 650 660
1350 1360 1370
pF1KB9 NKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
:. .:
XP_016 NRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHS
670 680 690 700 710 720
>>XP_006710945 (OMIM: 602600,608446) PREDICTED: low-dens (901 aa)
initn: 486 init1: 258 opt: 674 Z-score: 452.9 bits: 95.6 E(85289): 1.7e-18
Smith-Waterman score: 679; 27.4% identity (51.5% similar) in 635 aa overlap (754-1346:77-672)
730 740 750 760 770 780
pF1KB9 LNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVD
: : : . : :.. ::. : :
XP_006 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCD
50 60 70 80 90 100
790 800 810 820 830
pF1KB9 YTCECASGYQGDGRNCVDENECATGFHRCGPNS-VCINLPGSYRCE----CRSG------
:: .: . . .:. . : . :::.: :. :.:.::. :..:
XP_006 GEEECPDGSDESEATCTKQV-CPAEKLSCGPTSHKCV--PASWRCDGEKDCEGGADEAGC
110 120 130 140 150 160
840 850 860 870 880
pF1KB9 ------YEFADDRHTC---ILITPPANPCEDGSHT--CA-PAGQARCVHHGGSTFSCACL
.:: ..: ... . : ::: :: :: : . ::. . ::.
XP_006 ATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDG-GGACI
170 180 190 200 210 220
890 900 910 920 930 940
pF1KB9 PGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPC
: . : .: :.: :: . :: :: . : .:.: :
XP_006 P----ERWVCDRQFDC-EDRSDEAAELCGRPG-------PGATSAPAAC---ATASQFAC
230 240 250 260
950 960 970 980 990
pF1KB9 EQQQRHAQAQYAYPGARFHIPQCDEQGNFLPL-QCHGSTGFCW---CVDPDGHEVPGTQT
.. . .. . : : . :: :: :.:. : :: : .
XP_006 RSGE-CVHLGWRCDGDRDCKDKSDEADC--PLGTCRGDEFQCGDGTCVLAIKHCNQEQDC
270 280 290 300 310 320
1000 1010 1020 1030 1040
pF1KB9 PPGSTPPHCGPSPEPTQRPPT-ICERWR----ENLLEHYGGTPR---DDQYVPQCDDLGH
: :: : : ::: . .: : .. :.. :: . : . .: .
XP_006 PDGSDEAGC------LQVPPTFLGNRRRPRGLNECLHNNGGCSHICTDLKIGFECTCPAG
330 340 350 360 370
1050 1060 1070 1080 1090 1100
pF1KB9 FIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDV-TPPSVG
: :. . .:. : : :. . . : : .. . . . ::
XP_006 FQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPS--
380 390 400 410 420 430
1110 1120 1130 1140 1150 1160
pF1KB9 TFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTIS
:..:. ... . : .... .. . :.. .:..: . .:: :.. : :
XP_006 --LIFTNRHEVRRIDL----VKRNYSRLIPMLKN--VVALDVEVATNRIYWCDLSYRKIY
440 450 460 470 480
1170 1180 1190 1200 1210 1220
pF1KB9 RAGLELGAEP---ETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLF
: .. ...: :.... : ::::::.: ... .::::: : : .::..:..::
XP_006 SAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLF
490 500 510 520 530 540
1230 1240 1250 1260 1270 1280
pF1KB9 YTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPF
.: .::::::::.:: .::.::. .: ::: :.:.: .:. :.. .: :::.:.: .
XP_006 SRNLSEPRAIAVDPLRGFMYWSDWGDQA-KIEKSGLNGVDRQTLVSDNIEWPNGITLDLL
550 560 570 580 590 600
1290 1300 1310 1320 1330 1340
pF1KB9 SKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVSYADHFYHTDWRRDGVVSV
:. : :.:. ..: .: .:... .. :..::.:. . :. . :: . ... :.
XP_006 SQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSA
610 620 630 640 650 660
1350 1360 1370
pF1KB9 NKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
:. .:
XP_006 NRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHS
670 680 690 700 710 720
>>XP_006710944 (OMIM: 602600,608446) PREDICTED: low-dens (917 aa)
initn: 486 init1: 258 opt: 674 Z-score: 452.8 bits: 95.6 E(85289): 1.8e-18
Smith-Waterman score: 679; 27.4% identity (51.5% similar) in 635 aa overlap (754-1346:77-672)
730 740 750 760 770 780
pF1KB9 LNVDRVFALYNDEERVLRFAVTNQIGPVKEDSDPTPVNPCYDGSHMCDTTARCHPGTGVD
: : : . : :.. ::. : :
XP_006 CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADSDFTCDNGHCIHERWKCD
50 60 70 80 90 100
790 800 810 820 830
pF1KB9 YTCECASGYQGDGRNCVDENECATGFHRCGPNS-VCINLPGSYRCE----CRSG------
:: .: . . .:. . : . :::.: :. :.:.::. :..:
XP_006 GEEECPDGSDESEATCTKQV-CPAEKLSCGPTSHKCV--PASWRCDGEKDCEGGADEAGC
110 120 130 140 150 160
840 850 860 870 880
pF1KB9 ------YEFADDRHTC---ILITPPANPCEDGSHT--CA-PAGQARCVHHGGSTFSCACL
.:: ..: ... . : ::: :: :: : . ::. . ::.
XP_006 ATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGCADPACGPREFRCGGDG-GGACI
170 180 190 200 210 220
890 900 910 920 930 940
pF1KB9 PGYAGDGHQCTDVDECSENRCHPAATCYNTPGSFSCRCQPGYYGDGFQCIPDSTSSLTPC
: . : .: :.: :: . :: :: . : .:.: :
XP_006 P----ERWVCDRQFDC-EDRSDEAAELCGRPG-------PGATSAPAAC---ATASQFAC
230 240 250 260
950 960 970 980 990
pF1KB9 EQQQRHAQAQYAYPGARFHIPQCDEQGNFLPL-QCHGSTGFCW---CVDPDGHEVPGTQT
.. . .. . : : . :: :: :.:. : :: : .
XP_006 RSGE-CVHLGWRCDGDRDCKDKSDEADC--PLGTCRGDEFQCGDGTCVLAIKHCNQEQDC
270 280 290 300 310 320
1000 1010 1020 1030 1040
pF1KB9 PPGSTPPHCGPSPEPTQRPPT-ICERWR----ENLLEHYGGTPR---DDQYVPQCDDLGH
: :: : : ::: . .: : .. :.. :: . : . .: .
XP_006 PDGSDEAGC------LQVPPTFLGNRRRPRGLNECLHNNGGCSHICTDLKIGFECTCPAG
330 340 350 360 370
1050 1060 1070 1080 1090 1100
pF1KB9 FIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPACIPTVAPPMVRPTPRPDV-TPPSVG
: :. . .:. : : :. . . : : .. . . . ::
XP_006 FQLLDQKTCGDIDECKDPDACSQICVNYKGYFKCECYPGYEMDLLTKNCKAAAGKSPS--
380 390 400 410 420 430
1110 1120 1130 1140 1150 1160
pF1KB9 TFLLYTQGQQIGYLPLNGTRLQKDAAKTLLSLHGSIIVGIDYDCRERMVYWTDVAGRTIS
:..:. ... . : .... .. . :.. .:..: . .:: :.. : :
XP_006 --LIFTNRHEVRRIDL----VKRNYSRLIPMLKN--VVALDVEVATNRIYWCDLSYRKIY
440 450 460 470 480
1170 1180 1190 1200 1210 1220
pF1KB9 RAGLELGAEP---ETIVNSGLISPEGLAIDHIRRTMYWTDSVLDKIESALLDGSERKVLF
: .. ...: :.... : ::::::.: ... .::::: : : .::..:..::
XP_006 SAYMDKASDPKEQEVLIDEQLHSPEGLAVDWVHKHIYWTDSGNKTISVATVDGGRRRTLF
490 500 510 520 530 540
1230 1240 1250 1260 1270 1280
pF1KB9 YTDLVNPRAIAVDPIRGNLYWTDWNREAPKIETSSLDGENRRILINTDIGLPNGLTFDPF
.: .::::::::.:: .::.::. .: ::: :.:.: .:. :.. .: :::.:.: .
XP_006 SRNLSEPRAIAVDPLRGFMYWSDWGDQA-KIEKSGLNGVDRQTLVSDNIEWPNGITLDLL
550 560 570 580 590 600
1290 1300 1310 1320 1330 1340
pF1KB9 SKLLCWADAGTKKLECTLPDGTGRRVIQNN---LKYPFSIVSYADHFYHTDWRRDGVVSV
:. : :.:. ..: .: .:... .. :..::.:. . :. . :: . ... :.
XP_006 SQRLYWVDSKLHQLSSIDFSGGNRKTLISSTDFLSHPFGIAVFEDKVFWTDLENEAIFSA
610 620 630 640 650 660
1350 1360 1370
pF1KB9 NKHSGQFTDEYLPEQRSHLYGITAVYPYCPTGRK
:. .:
XP_006 NRLNGLEISILAENLNNPHDIVIFHELKQPRAPDACELSVQPNGGCEYLCLPAPQISSHS
670 680 690 700 710 720
1375 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:57:24 2016 done: Thu Nov 3 22:57:26 2016
Total Scan time: 12.990 Total Display time: 0.610
Function used was FASTA [36.3.4 Apr, 2011]