FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9027, 239 aa 1>>>pF1KB9027 239 - 239 aa - 239 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9740+/-0.000823; mu= 16.5893+/- 0.049 mean_var=70.0867+/-14.741, 0's: 0 Z-trim(107.8): 16 B-trim: 527 in 1/48 Lambda= 0.153199 statistics sampled from 9792 (9807) to 9792 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.301), width: 16 Scan time: 2.200 The best scores are: opt bits E(32554) CCDS11073.1 DERL2 gene_id:51009|Hs108|chr17 ( 239) 1640 371.2 3.5e-103 CCDS33615.1 DERL3 gene_id:91319|Hs108|chr22 ( 235) 1272 289.8 1e-78 CCDS42986.1 DERL3 gene_id:91319|Hs108|chr22 ( 205) 1158 264.6 3.6e-71 CCDS46672.1 DERL3 gene_id:91319|Hs108|chr22 ( 239) 1158 264.6 4.1e-71 CCDS6337.1 DERL1 gene_id:79139|Hs108|chr8 ( 251) 487 116.3 1.9e-26 CCDS47915.1 DERL1 gene_id:79139|Hs108|chr8 ( 231) 416 100.6 9.3e-22 CCDS76927.1 DERL2 gene_id:51009|Hs108|chr17 ( 74) 355 86.7 4.5e-18 CCDS83319.1 DERL1 gene_id:79139|Hs108|chr8 ( 151) 250 63.8 7.4e-11 >>CCDS11073.1 DERL2 gene_id:51009|Hs108|chr17 (239 aa) initn: 1640 init1: 1640 opt: 1640 Z-score: 1966.0 bits: 371.2 E(32554): 3.5e-103 Smith-Waterman score: 1640; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239) 10 20 30 40 50 60 pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG 190 200 210 220 230 >>CCDS33615.1 DERL3 gene_id:91319|Hs108|chr22 (235 aa) initn: 1272 init1: 1272 opt: 1272 Z-score: 1526.5 bits: 289.8 E(32554): 1e-78 Smith-Waterman score: 1272; 78.0% identity (94.3% similar) in 227 aa overlap (1-227:1-227) 10 20 30 40 50 60 pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN ::.:.: :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.:: CCDS33 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: :: CCDS33 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH :::. :::::::::.: ::.::::::.::::::::.::::::::::::.:::::::::: CCDS33 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG ::.:::::::::::: :.:.::..:: ..:.: ::::: :::::.:: CCDS33 IYYFLEDVFPNQPGGKRLLQTPGFLKLLLDAPAEDPNYLPLPEEQPGPHLPPPQQ 190 200 210 220 230 >>CCDS42986.1 DERL3 gene_id:91319|Hs108|chr22 (205 aa) initn: 1185 init1: 1158 opt: 1158 Z-score: 1391.1 bits: 264.6 E(32554): 3.6e-71 Smith-Waterman score: 1158; 79.0% identity (95.1% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN ::.:.: :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.:: CCDS42 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: :: CCDS42 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH :::. :::::::::.: ::.::::::.::::::::.::::::::::::.:::::::::: CCDS42 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG ::.:::::::::::: :.:.::..: CCDS42 IYYFLEDVFPNQPGGKRLLQTPGFL 190 200 >>CCDS46672.1 DERL3 gene_id:91319|Hs108|chr22 (239 aa) initn: 1158 init1: 1158 opt: 1158 Z-score: 1390.2 bits: 264.6 E(32554): 4.1e-71 Smith-Waterman score: 1158; 79.0% identity (95.1% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN ::.:.: :.::.: :.::::.:::::::::::::..::::::::.:.:..::.:::.:: CCDS46 MAWQGLAAEFLQVPAVTRAYTAACVLTTAAVQLELLSPFQLYFNPHLVFRKFQVWRLVTN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL ::::::.::.:.:::.:..:::::::::::::::::::::::::: ::::.::. :: :: CCDS46 FLFFGPLGFSFFFNMLFVFRYCRMLEEGSFRGRTADFVFMFLFGGVLMTLLGLLGSLFFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGH :::. :::::::::.: ::.::::::.::::::::.::::::::::::.:::::::::: CCDS46 GQALMAMLVYVWSRRSPRVRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGH 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG ::.:::::::::::: :.:.::..: CCDS46 IYYFLEDVFPNQPGGKRLLQTPGFLGLQSSKAPAGSSLTIWTQQSQGGPGTAGELAAPS 190 200 210 220 230 >>CCDS6337.1 DERL1 gene_id:79139|Hs108|chr8 (251 aa) initn: 516 init1: 370 opt: 487 Z-score: 588.4 bits: 116.3 E(32554): 1.9e-26 Smith-Waterman score: 499; 35.5% identity (63.2% similar) in 242 aa overlap (10-238:8-249) 10 20 30 40 50 60 pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN . .:: ..: . .: : . . .: ::.: :.. :: .. .::::: :: CCDS63 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITA 10 20 30 40 50 70 80 90 100 110 pF1KB9 FLFF--GP-VGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSL ..: :: .:: .: :. :::.: :: :.: :: ::..::.::. . ... :: ... CCDS63 TFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 VFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIA .: . . ..:::.. : . ..:. :.: .::::..::. ..:.:.: .:.: CCDS63 QLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNL 120 130 140 150 160 170 180 190 200 210 220 pF1KB9 VGHIYFFLEDVFPNQPGGIRILKTPSILK----------AIFDTPDEDPNYNPLPEERPG :::.:::: .: . :: .:.::..: . : .: . . : CCDS63 VGHLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGG 180 190 200 210 220 230 230 pF1KB9 GFAWGEGQRLGG ::.: ::: CCDS63 RHNWGQGFRLGDQ 240 250 >>CCDS47915.1 DERL1 gene_id:79139|Hs108|chr8 (231 aa) initn: 473 init1: 295 opt: 416 Z-score: 504.1 bits: 100.6 E(32554): 9.3e-22 Smith-Waterman score: 431; 33.2% identity (61.6% similar) in 232 aa overlap (10-238:8-229) 10 20 30 40 50 60 pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN . .:: ..: . .: : . . .: ::.: :.. :: .. .::::: :: CCDS47 MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITA 10 20 30 40 50 70 80 90 100 110 pF1KB9 FLFF--GP-VGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSL ..: :: .:: .: :. :::.: :: :.: :: ::..::.::. . ... :: ... CCDS47 TFYFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 VFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIA .: . . ..:::.. : . ..:. :.: .::::..::. ..:.: .:: : CCDS47 QLLMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSYPMDLGGRN 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 VGHIYFFLEDVFPNQPGGIRILKTPSILKAIFDTPDEDPNYNPLPEERPGGFAWGEGQRL :: .:.. ::. . .: .. . :.. . : ::.: :: CCDS47 FLSTPQFLYRWLPSRRGGVSGFGVPP--ASMRRAADQNGG--------GGRHNWGQGFRL 180 190 200 210 220 pF1KB9 GG : CCDS47 GDQ 230 >>CCDS76927.1 DERL2 gene_id:51009|Hs108|chr17 (74 aa) initn: 353 init1: 353 opt: 355 Z-score: 438.0 bits: 86.7 E(32554): 4.5e-18 Smith-Waterman score: 355; 88.9% identity (95.2% similar) in 63 aa overlap (1-63:1-62) 10 20 30 40 50 60 pF1KB9 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITN :::::::::::::::::::::::::::::::::::::::::::::::::::::. .: : CCDS76 MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQVLQLDT- 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 FLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFL ..: CCDS76 YIFSWKMYFPINLVE 60 70 >>CCDS83319.1 DERL1 gene_id:79139|Hs108|chr8 (151 aa) initn: 277 init1: 242 opt: 250 Z-score: 308.4 bits: 63.8 E(32554): 7.4e-11 Smith-Waterman score: 262; 31.5% identity (60.4% similar) in 149 aa overlap (100-238:1-149) 70 80 90 100 110 120 pF1KB9 NFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLV :.::. . ... :: ... .: . . .. CCDS83 MLLFNWICIVITGLAMDMQLLMIPLIMSVL 10 20 30 130 140 150 160 170 180 pF1KB9 YVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVF :::.. : . ..:. :.: .::::..::. ..:.:.: .:.: :::.:::: . CCDS83 YVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRY 40 50 60 70 80 90 190 200 210 220 230 pF1KB9 PNQPGGIRILKTPSILK----------AIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG : . :: .:.::..: . : .: . . : ::.: ::: CCDS83 PMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 100 110 120 130 140 150 CCDS83 Q 239 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:58:05 2016 done: Thu Nov 3 22:58:05 2016 Total Scan time: 2.200 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]