FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9038, 444 aa 1>>>pF1KB9038 444 - 444 aa - 444 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2551+/-0.000391; mu= 18.1961+/- 0.025 mean_var=69.7895+/-13.737, 0's: 0 Z-trim(112.6): 63 B-trim: 511 in 2/51 Lambda= 0.153525 statistics sampled from 21502 (21570) to 21502 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.62), E-opt: 0.2 (0.253), width: 16 Scan time: 8.390 The best scores are: opt bits E(85289) NP_821133 (OMIM: 156610,191130,615771) tubulin bet ( 444) 2987 670.9 1.9e-192 NP_006079 (OMIM: 602660) tubulin beta-4B chain [Ho ( 445) 2929 658.0 1.4e-188 NP_006078 (OMIM: 602662) tubulin beta-4A chain iso ( 444) 2893 650.0 3.5e-186 NP_001276058 (OMIM: 602662) tubulin beta-4A chain ( 444) 2893 650.0 3.5e-186 NP_001276056 (OMIM: 602662) tubulin beta-4A chain ( 489) 2893 650.1 3.8e-186 NP_001276052 (OMIM: 602662) tubulin beta-4A chain ( 495) 2893 650.1 3.8e-186 NP_821080 (OMIM: 610031,612850) tubulin beta-2B ch ( 445) 2885 648.3 1.2e-185 NP_001060 (OMIM: 615101,615763) tubulin beta-2A ch ( 445) 2866 644.1 2.2e-184 NP_001280141 (OMIM: 156610,191130,615771) tubulin ( 464) 2862 643.2 4.2e-184 NP_006077 (OMIM: 600638,602661,614039) tubulin bet ( 450) 2793 627.9 1.6e-179 NP_001290453 (OMIM: 615103) tubulin beta-6 chain i ( 446) 2741 616.4 4.8e-176 NP_115914 (OMIM: 615103) tubulin beta-6 chain isof ( 446) 2741 616.4 4.8e-176 NP_817124 (OMIM: 616768,616780) tubulin beta-8 cha ( 444) 2738 615.7 7.5e-176 NP_001280143 (OMIM: 156610,191130,615771) tubulin ( 400) 2599 584.9 1.3e-166 NP_001280144 (OMIM: 156610,191130,615771) tubulin ( 372) 2492 561.2 1.6e-159 NP_001280145 (OMIM: 156610,191130,615771) tubulin ( 372) 2492 561.2 1.6e-159 NP_110400 (OMIM: 612901,613112) tubulin beta-1 cha ( 451) 2433 548.2 1.6e-155 NP_001276060 (OMIM: 602662) tubulin beta-4A chain ( 372) 2418 544.8 1.4e-154 NP_001276059 (OMIM: 602662) tubulin beta-4A chain ( 372) 2418 544.8 1.4e-154 NP_001184110 (OMIM: 600638,602661,614039) tubulin ( 378) 2347 529.1 7.8e-150 NP_001290456 (OMIM: 615103) tubulin beta-6 chain i ( 374) 2328 524.9 1.4e-148 XP_011517761 (OMIM: 616768,616780) PREDICTED: tubu ( 372) 2318 522.6 6.6e-148 XP_016883574 (OMIM: 612901,613112) PREDICTED: tubu ( 429) 2279 514.0 2.9e-145 NP_001297244 (OMIM: 615101,615763) tubulin beta-2A ( 360) 2253 508.2 1.4e-143 NP_001290457 (OMIM: 615103) tubulin beta-6 chain i ( 381) 2189 494.1 2.7e-139 NP_001290455 (OMIM: 615103) tubulin beta-6 chain i ( 409) 2180 492.1 1.1e-138 XP_016871681 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 2040 461.0 2.1e-129 XP_016871682 (OMIM: 616768,616780) PREDICTED: tubu ( 332) 2040 461.0 2.1e-129 NP_001290459 (OMIM: 615103) tubulin beta-6 chain i ( 300) 1835 415.6 8.8e-116 NP_001290458 (OMIM: 615103) tubulin beta-6 chain i ( 300) 1835 415.6 8.8e-116 XP_011517762 (OMIM: 616768,616780) PREDICTED: tubu ( 291) 1658 376.4 5.5e-104 NP_005991 (OMIM: 191110,616208) tubulin alpha-4A c ( 448) 1296 296.3 1.1e-79 NP_006073 (OMIM: 602530) tubulin alpha-1B chain [H ( 451) 1288 294.6 3.6e-79 NP_005992 (OMIM: 602528) tubulin alpha-3C/D chain ( 450) 1281 293.0 1.1e-78 NP_001257328 (OMIM: 602529,611603) tubulin alpha-1 ( 451) 1280 292.8 1.2e-78 NP_006000 (OMIM: 602529,611603) tubulin alpha-1A c ( 451) 1280 292.8 1.2e-78 NP_061816 (OMIM: 605742,613180) tubulin alpha-8 ch ( 449) 1262 288.8 2e-77 NP_001265481 (OMIM: 191110,616208) tubulin alpha-4 ( 433) 1244 284.8 3e-76 NP_001257329 (OMIM: 602529,611603) tubulin alpha-1 ( 416) 1173 269.1 1.6e-71 NP_001180343 (OMIM: 605742,613180) tubulin alpha-8 ( 383) 1092 251.1 3.7e-66 NP_001061 (OMIM: 191135,615412) tubulin gamma-1 ch ( 451) 1007 232.3 2e-60 NP_057521 (OMIM: 605785) tubulin gamma-2 chain iso ( 451) 998 230.3 7.9e-60 NP_001280142 (OMIM: 156610,191130,615771) tubulin ( 242) 848 196.9 4.8e-50 XP_016860313 (OMIM: 191110,616208) PREDICTED: tubu ( 295) 787 183.5 6.5e-46 NP_001307438 (OMIM: 605785) tubulin gamma-2 chain ( 460) 619 146.4 1.5e-34 NP_001290454 (OMIM: 615103) tubulin beta-6 chain i ( 104) 555 131.8 8.3e-31 NP_057346 (OMIM: 607345) tubulin epsilon chain [Ho ( 475) 524 125.4 3.3e-28 XP_016879942 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 514 123.0 1.1e-27 XP_011522916 (OMIM: 605785) PREDICTED: tubulin gam ( 298) 514 123.0 1.1e-27 XP_016879944 (OMIM: 605785) PREDICTED: tubulin gam ( 274) 475 114.4 3.9e-25 >>NP_821133 (OMIM: 156610,191130,615771) tubulin beta ch (444 aa) initn: 2987 init1: 2987 opt: 2987 Z-score: 3576.1 bits: 670.9 E(85289): 1.9e-192 Smith-Waterman score: 2987; 100.0% identity (100.0% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KB9 EYQQYQDATAEEEEDFGEEAEEEA :::::::::::::::::::::::: NP_821 EYQQYQDATAEEEEDFGEEAEEEA 430 440 >>NP_006079 (OMIM: 602660) tubulin beta-4B chain [Homo s (445 aa) initn: 2929 init1: 2929 opt: 2929 Z-score: 3506.7 bits: 658.0 E(85289): 1.4e-188 Smith-Waterman score: 2929; 97.7% identity (99.5% similar) in 443 aa overlap (1-443:1-443) 10 20 30 40 50 60 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV ::::::.:::::::::::::::::::::::::::::::::::::.::.:::::::::::: NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KB9 EYQQYQDATAEEEEDFGEEAEEEA ::::::::::::: .: :::::: NP_006 EYQQYQDATAEEEGEFEEEAEEEVA 430 440 >>NP_006078 (OMIM: 602662) tubulin beta-4A chain isoform (444 aa) initn: 2909 init1: 2872 opt: 2893 Z-score: 3463.6 bits: 650.0 E(85289): 3.5e-186 Smith-Waterman score: 2893; 96.8% identity (99.3% similar) in 443 aa overlap (1-443:1-442) 10 20 30 40 50 60 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV ::::::.:::::::::::::::::::::::::::::::::::::.::.:::::::::.:: NP_006 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_006 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_006 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::.::.::::::::::::::::::::::::: NP_006 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KB9 EYQQYQDATAEEEEDFGEEAEEEA :::::::::::: : : :::::: NP_006 EYQQYQDATAEEGE-FEEEAEEEVA 430 440 >>NP_001276058 (OMIM: 602662) tubulin beta-4A chain isof (444 aa) initn: 2909 init1: 2872 opt: 2893 Z-score: 3463.6 bits: 650.0 E(85289): 3.5e-186 Smith-Waterman score: 2893; 96.8% identity (99.3% similar) in 443 aa overlap (1-443:1-442) 10 20 30 40 50 60 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV ::::::.:::::::::::::::::::::::::::::::::::::.::.:::::::::.:: NP_001 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::.::::::::::::::::::::::::::::::::::::::::::::::::::.::::: NP_001 PRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV ::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::: NP_001 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM ::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::: NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::::::::::::::::::.::.::::::::::::::::::::::::: NP_001 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS ::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KB9 EYQQYQDATAEEEEDFGEEAEEEA :::::::::::: : : :::::: NP_001 EYQQYQDATAEEGE-FEEEAEEEVA 430 440 >>NP_001276056 (OMIM: 602662) tubulin beta-4A chain isof (489 aa) initn: 2909 init1: 2872 opt: 2893 Z-score: 3463.0 bits: 650.1 E(85289): 3.8e-186 Smith-Waterman score: 2893; 96.8% identity (99.3% similar) in 443 aa overlap (1-443:46-487) 10 20 30 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGI ::::::.::::::::::::::::::::::: NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB9 DPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNF ::::::::::::::.::.:::::::::.:::::.:::::::::::::::::::::::::: NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB9 VFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL 140 150 160 170 180 190 160 170 180 190 200 210 pF1KB9 LISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 200 210 220 230 240 250 220 230 240 250 260 270 pF1KB9 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF 260 270 280 290 300 310 280 290 300 310 320 330 pF1KB9 APLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM 320 330 340 350 360 370 340 350 360 370 380 390 pF1KB9 LNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFR :.::.:::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR 380 390 400 410 420 430 400 410 420 430 440 pF1KB9 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA :::::::::::::::::::::::::::::::::::::::::: : : :::::: NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGE-FEEEAEEEVA 440 450 460 470 480 >>NP_001276052 (OMIM: 602662) tubulin beta-4A chain isof (495 aa) initn: 2909 init1: 2872 opt: 2893 Z-score: 3462.9 bits: 650.1 E(85289): 3.8e-186 Smith-Waterman score: 2893; 96.8% identity (99.3% similar) in 443 aa overlap (1-443:52-493) 10 20 30 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGI ::::::.::::::::::::::::::::::: NP_001 AVSAASSTLAAAAAPRARATAAASTLSATAMREIVHLQAGQCGNQIGAKFWEVISDEHGI 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 DPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNF ::::::::::::::.::.:::::::::.:::::.:::::::::::::::::::::::::: NP_001 DPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNF 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 VFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: NP_001 VFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTL 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 LISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI ::::::::.::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDI 210 220 230 240 250 260 220 230 240 250 260 270 pF1KB9 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGF 270 280 290 300 310 320 280 290 300 310 320 330 pF1KB9 APLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM ::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::: NP_001 APLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQM 330 340 350 360 370 380 340 350 360 370 380 390 pF1KB9 LNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFR :.::.:::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_001 LSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR 390 400 410 420 430 440 400 410 420 430 440 pF1KB9 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA :::::::::::::::::::::::::::::::::::::::::: : : :::::: NP_001 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGE-FEEEAEEEVA 450 460 470 480 490 >>NP_821080 (OMIM: 610031,612850) tubulin beta-2B chain (445 aa) initn: 2882 init1: 2882 opt: 2885 Z-score: 3454.0 bits: 648.3 E(85289): 1.2e-185 Smith-Waterman score: 2885; 95.7% identity (99.3% similar) in 445 aa overlap (1-444:1-445) 10 20 30 40 50 60 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV ::::::::::::::::::::::::::::::::::.:::::::::.::.::::::::.::: NP_821 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::.:::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_821 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM ::::::::::::::::::::::::::::::::::::::::::::::::::::.::.:::: NP_821 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_821 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_821 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KB9 EYQQYQDATAEEEEDFGEE-AEEEA ::::::::::.:. .: :: .:.:: NP_821 EYQQYQDATADEQGEFEEEEGEDEA 430 440 >>NP_001060 (OMIM: 615101,615763) tubulin beta-2A chain (445 aa) initn: 2863 init1: 2863 opt: 2866 Z-score: 3431.3 bits: 644.1 E(85289): 2.2e-184 Smith-Waterman score: 2866; 95.3% identity (99.1% similar) in 445 aa overlap (1-444:1-445) 10 20 30 40 50 60 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV ::::::::::::::::::::::::::::::::::.:::::::::.::.::::::.:.::: NP_001 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV :::.:::::::::::::::::::::::::::::::::::::::::::::.:::::::::: NP_001 RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL :::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::: NP_001 EPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM ::::::::::::::::::::::::::::::::::::::::::::::::::::.::.:::: NP_001 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG :::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::: NP_001 AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::..::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KB9 EYQQYQDATAEEEEDFGEE-AEEEA ::::::::::.:. .: :: .:.:: NP_001 EYQQYQDATADEQGEFEEEEGEDEA 430 440 >>NP_001280141 (OMIM: 156610,191130,615771) tubulin beta (464 aa) initn: 2862 init1: 2862 opt: 2862 Z-score: 3426.2 bits: 643.2 E(85289): 4.2e-184 Smith-Waterman score: 2862; 100.0% identity (100.0% similar) in 426 aa overlap (19-444:39-464) 10 20 30 40 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRIS :::::::::::::::::::::::::::::: NP_001 ANWDPSRSGVRDHPGQQSETLPHATFLQKIKFWEVISDEHGIDPTGTYHGDSDLQLDRIS 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 VYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 GAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFS 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 VVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHL 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB9 VSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPE 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 LTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNN 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB9 VKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEF 370 380 390 400 410 420 410 420 430 440 pF1KB9 TEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA :::::::::::::::::::::::::::::::::::: NP_001 TEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA 430 440 450 460 >>NP_006077 (OMIM: 600638,602661,614039) tubulin beta-3 (450 aa) initn: 2793 init1: 2793 opt: 2793 Z-score: 3343.8 bits: 627.9 E(85289): 1.6e-179 Smith-Waterman score: 2793; 92.6% identity (97.7% similar) in 444 aa overlap (1-444:1-444) 10 20 30 40 50 60 pF1KB9 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYV ::::::::::::::::::::::::::::::::.:.: :::::::.:::::::::.. ::: NP_006 MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPSGNYVGDSDLQLERISVYYNEASSHKYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV ::::::::::::::::::: ::..::::::.::::::::::::::::::::::::::::: NP_006 PRAILVDLEPGTMDSVRSGAFGHLFRPDNFIFGQSGAGNNWAKGHYTEGAELVDSVLDVV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 RKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVV ::: :.::::::::::::::::::::::::::::.::::::::::::::::::::::::: NP_006 RKECENCDCLQGFQLTHSLGGGTGSGMGTLLISKVREEYPDRIMNTFSVVPSPKVSDTVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL ::::::::.::::::::::::::::::::::::::::.:::::::::::::::::::: : NP_006 EPYNATLSIHQLVENTDETYCIDNEALYDICFRTLKLATPTYGDLNHLVSATMSGVTTSL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMM ::::::::::::::::::::::::::::::::::.:::::::::::::::::.::::::: NP_006 RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMM 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG ::::::::::::::.:::::::::::::::: .:.:::::::::::::::.::::::::: NP_006 AACDPRHGRYLTVATVFRGRMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRG 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 LKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS :::. ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 LKMSSTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS 370 380 390 400 410 420 430 440 pF1KB9 EYQQYQDATAEEEEDFGEEAEEEA ::::::::::::: .. :. :::. NP_006 EYQQYQDATAEEEGEMYEDDEEESEAQGPK 430 440 450 444 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:59:11 2016 done: Fri Nov 4 16:59:12 2016 Total Scan time: 8.390 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]