FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9055, 978 aa 1>>>pF1KB9055 978 - 978 aa - 978 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3661+/-0.000951; mu= 12.1373+/- 0.058 mean_var=119.6115+/-24.047, 0's: 0 Z-trim(107.9): 15 B-trim: 0 in 0/53 Lambda= 0.117270 statistics sampled from 9826 (9838) to 9826 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.302), width: 16 Scan time: 4.850 The best scores are: opt bits E(32554) CCDS5574.1 GTF2I gene_id:2969|Hs108|chr7 ( 978) 6456 1104.1 0 CCDS5575.1 GTF2I gene_id:2969|Hs108|chr7 ( 977) 6233 1066.3 0 CCDS5573.1 GTF2I gene_id:2969|Hs108|chr7 ( 998) 4822 827.6 0 CCDS47614.1 GTF2I gene_id:2969|Hs108|chr7 ( 957) 4587 787.8 0 CCDS64680.1 GTF2I gene_id:2969|Hs108|chr7 ( 274) 1777 312.2 9.2e-85 CCDS5576.1 GTF2IRD2 gene_id:84163|Hs108|chr7 ( 949) 1588 280.5 1.1e-74 CCDS34659.1 GTF2IRD2B gene_id:389524|Hs108|chr7 ( 949) 1587 280.3 1.3e-74 CCDS5571.1 GTF2IRD1 gene_id:9569|Hs108|chr7 ( 959) 624 117.4 1.4e-25 CCDS64682.1 GTF2IRD2 gene_id:84163|Hs108|chr7 ( 108) 451 87.7 1.4e-17 CCDS47613.1 GTF2IRD1 gene_id:9569|Hs108|chr7 ( 944) 355 71.8 7.1e-12 CCDS56492.1 GTF2IRD1 gene_id:9569|Hs108|chr7 ( 976) 355 71.9 7.3e-12 >>CCDS5574.1 GTF2I gene_id:2969|Hs108|chr7 (978 aa) initn: 6456 init1: 6456 opt: 6456 Z-score: 5904.9 bits: 1104.1 E(32554): 0 Smith-Waterman score: 6456; 100.0% identity (100.0% similar) in 978 aa overlap (1-978:1-978) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 910 920 930 940 950 960 970 pF1KB9 IKETDGSSQIKQEPDPTW :::::::::::::::::: CCDS55 IKETDGSSQIKQEPDPTW 970 >>CCDS5575.1 GTF2I gene_id:2969|Hs108|chr7 (977 aa) initn: 6217 init1: 4582 opt: 6233 Z-score: 5701.0 bits: 1066.3 E(32554): 0 Smith-Waterman score: 6233; 97.0% identity (98.0% similar) in 979 aa overlap (1-978:1-977) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 EESEDPDYYQYNIQ-GSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYS :::::::::::::: : .... .: . : . : : :: .: :.:: :::::: CCDS55 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGS--HHSSEGNEGTEMEVPAEDDDYS 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 PPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 KGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 NSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHP 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 NDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 NDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTP 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 VKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFR 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 SPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNS 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 KVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVEN 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 KIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 KIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERL 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 SKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPS 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB9 YLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 YLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATE 900 910 920 930 940 950 960 970 pF1KB9 EIKETDGSSQIKQEPDPTW ::::::::::::::::::: CCDS55 EIKETDGSSQIKQEPDPTW 960 970 >>CCDS5573.1 GTF2I gene_id:2969|Hs108|chr7 (998 aa) initn: 4816 init1: 4816 opt: 4822 Z-score: 4410.7 bits: 827.6 E(32554): 0 Smith-Waterman score: 6406; 98.0% identity (98.0% similar) in 998 aa overlap (1-978:1-998) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 pF1KB9 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPAEDSTQHVP :::::::::::::: :::::::::::::::::::::::::: CCDS55 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB9 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB9 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB9 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB9 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB9 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB9 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB9 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB9 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB9 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB9 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 910 920 930 940 950 960 950 960 970 pF1KB9 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW :::::::::::::::::::::::::::::::::::::: CCDS55 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 970 980 990 >>CCDS47614.1 GTF2I gene_id:2969|Hs108|chr7 (957 aa) initn: 4582 init1: 4582 opt: 4587 Z-score: 4196.1 bits: 787.8 E(32554): 0 Smith-Waterman score: 6271; 97.9% identity (97.9% similar) in 978 aa overlap (1-978:1-957) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP :::::::::::::::::::::::::::::::::: ::::: CCDS47 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAED---------------------DDYSP 250 260 270 310 320 330 340 350 360 pF1KB9 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB9 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB9 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB9 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB9 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB9 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB9 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 760 770 780 790 800 810 850 860 870 880 890 900 pF1KB9 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 820 830 840 850 860 870 910 920 930 940 950 960 pF1KB9 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 880 890 900 910 920 930 970 pF1KB9 IKETDGSSQIKQEPDPTW :::::::::::::::::: CCDS47 IKETDGSSQIKQEPDPTW 940 950 >>CCDS64680.1 GTF2I gene_id:2969|Hs108|chr7 (274 aa) initn: 1777 init1: 1777 opt: 1777 Z-score: 1635.2 bits: 312.2 E(32554): 9.2e-85 Smith-Waterman score: 1777; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS64 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP ::::::::::::::::::::::::::::::::: CCDS64 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEG 250 260 270 310 320 330 340 350 360 pF1KB9 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK >>CCDS5576.1 GTF2IRD2 gene_id:84163|Hs108|chr7 (949 aa) initn: 1904 init1: 934 opt: 1588 Z-score: 1454.1 bits: 280.5 E(32554): 1.1e-74 Smith-Waterman score: 1589; 45.3% identity (67.8% similar) in 653 aa overlap (1-642:1-629) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::.::::::.: :::.:::::::.::::::::::::::::::::::::::::::::: CCDS55 MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :: ::::.: ::::::.:::: : . ..: .: :.: . : : :::.::::: CCDS55 RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI ::::::::: ...::::::::::::::::::::::::::.:::::::::::::::::::: CCDS55 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK ::::.:::: :....:: :::::.:::.::. :::::.::::: :::::::. ::.:: CCDS55 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 180 190 200 210 220 230 250 260 270 280 290 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSET-SEDPEVEVTIEDDDYS .:::::.:::::.:::: :: .:: :::.: :::: :::: .::::.:: :: . : CCDS55 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 PPSKRPKAN--ELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAI :. .: : : : .: : ..:: : .::.::..:: ::...:: CCDS55 SSVTNSAAGVEDLNIVQVTVPDN---EKERLSSIEK----IKQLREQVNDLFSRKFGEAI 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 KAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKH- . :: .:: . . . ..:.: :. :. :. : ..::: : : :.:.. . CCDS55 GVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 ---ELLNSTREDLQLDKPASGVKEEWYAR--ITKLRKMVDQLFCKKFAEALGSTEAKAVP :: : .. ..:. . .:.: ....... :.::. . .... CCDS55 PGLELSNVGKR--KIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQ-SMSVSKEYNLRRH 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB9 YQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEV :: ... : :.: . :. . . . . . .:. .. ..... . CCDS55 YQTNHSKHYDQYMERM------RDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSP-- 470 480 490 500 510 540 550 560 570 580 pF1KB9 TQPRTNTPVKEDWNVRITKLRKQVEEI--FNLKFAQALGLTEAVKVPYPVFESNPEFLYV :: ::.. . :::.... . ... . . ....... . . .: CCDS55 TQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVS 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 EGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSP : : . .:. . : : . :. .. ... . .: : : :.:.. : CCDS55 EELLDTVPM-TGTKSGNEIFSRVEKSLKNFCIDWSKLVSVASTGTPAMVDANNGLVTKLK 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 KRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAK CCDS55 SRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLY 640 650 660 670 680 690 >>CCDS34659.1 GTF2IRD2B gene_id:389524|Hs108|chr7 (949 aa) initn: 1904 init1: 934 opt: 1587 Z-score: 1453.1 bits: 280.3 E(32554): 1.3e-74 Smith-Waterman score: 1590; 45.5% identity (67.8% similar) in 655 aa overlap (1-642:1-629) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::.::::::.: :::.:::::::.::::::::::::::::::::::::::::::::: CCDS34 MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :: ::::.: ::::::.:::: : . ..: .: :.: . : : :::.::::: CCDS34 RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI ::::::::: ...::::::::::::::::::::::::::.:::::::::::::::::::: CCDS34 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK ::::.:::: :....:: :::::.:::.::. :::::.::::: :::::::. ::.:: CCDS34 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 180 190 200 210 220 230 250 260 270 280 290 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSET-SEDPEVEVTIEDDDYS .:::::.:::::.:::: :: .:: :::.: :::: :::: .::::.:: :: . : CCDS34 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 PPSKRPKAN--ELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAI :. .: : : : .: : ..:: : .::.::..:: ::...:: CCDS34 SSVTNSAAGVEDLNIVQVTVPDN---EKERLSSIEK----IKQLREQVNDLFSRKFGEAI 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 KAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKH- . :: .:: . . . ..:.: :. :. :. : ..::: : : :.:.. . CCDS34 GVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 ---ELLNSTREDLQLDKPASGVKEEWYAR--ITKLRKMVDQLFCKKFAEALGSTEAKAVP :: : .. ..:. . .:.: ....... :.::. . .... CCDS34 PGLELSNVGKR--KIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQ-SMSVSKEYNLRRH 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB9 YQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEV :: ... : :.: . :. . . . . . .:. .. ..... . CCDS34 YQTNHSKHYDQYTERM------RDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSP-- 470 480 490 500 510 540 550 560 570 580 pF1KB9 TQPRTNTPVKEDWNVRITKLRKQVEEI--FNLKFAQALGLTEAVKVPYPVFESNPEFLYV :: ::.. . :::.... . ... . . ....... . . .: CCDS34 TQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVS 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 EGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELV--ISYLPPGMASKINTKALQ : : . .:. . : : . :. .. . :: .. .:: : :.:.. : CCDS34 EELLDTVPM-TGTKSGNEIFLRVEKSLK--KFCINWSRLVSVASTGTPAMVDANNGLVTK 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 SPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWN CCDS34 LKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTL 640 650 660 670 680 690 >>CCDS5571.1 GTF2IRD1 gene_id:9569|Hs108|chr7 (959 aa) initn: 1017 init1: 355 opt: 624 Z-score: 572.5 bits: 117.4 E(32554): 1.4e-25 Smith-Waterman score: 1318; 33.0% identity (59.2% similar) in 928 aa overlap (22-910:30-864) 10 20 30 40 50 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYET ..: :.:::.:::. :.: .:::::.::.. CCDS55 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 10 20 30 40 50 60 60 70 80 90 100 pF1KB9 DVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQAN-------RMSVD ..::::::.:: :.:.::..:.::...: : : .. :.. ... : :.. CCDS55 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 -AVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPEN . .. ::: ::. : :..:::...:::.:::..::. . ..:::::::.::..: . CCDS55 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 YDLATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEP :: .: :::.. : : .::: :: ::: :. . : : : . CCDS55 YDPKALMAILEHSHRIRFKLKRP-LED----GGR----DSKALVELNGVSLIP-----KG 190 200 210 220 230 240 250 260 270 280 pF1KB9 TEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAE-DSTQHVPSET ..: : :. : : .. : . .. . .:. . . :. : : .::. CCDS55 SRDCG--LHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDL 230 240 250 260 270 280 290 300 310 320 330 pF1KB9 SED---PEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKR---KVREFNFEKWNAR . . :: ..: .: . ...: . : :. . ..:.:: .. . . :::.: CCDS55 GLSRPMPEPKATGAQDFSDCCGQKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAF 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB9 ITD------LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRP : . ::. :. ::. .::.:. : .:: . : . . :.:. :::.:: CCDS55 IKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRP 350 360 370 380 390 400 400 410 420 430 440 pF1KB9 STYGIPRLERILLAKERIRFVIKKH--ELL---NSTREDLQLDKPASGVKEEWYARITK- :::.:.:.::: .. :.:.::. : . :. .: .::: :. :.... CCDS55 CTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASP-PEDTSAEVSRA 410 420 430 440 450 460 450 460 470 480 490 pF1KB9 -LRKMVDQLFCKK--FAEALG-STEAKAVPYQKFEAHPNDLYV--EGLPENIPFRSPSWY . .. . : ..: : .: .. . .. .:.:: . .:. : CCDS55 TVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTD 470 480 490 500 510 520 500 510 520 530 540 550 pF1KB9 GIPRLEKIIQVGNRIKFVIKRPELLT-HSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEI ..: . : . :.:: .. .: ..:. . ::... . : :::::: . CCDS55 SMPGHLPSEDSGYGM-------EMLTDKGLSEDARPE-ERPVEDSHGDVIRPLRKQVELL 530 540 550 560 570 560 570 580 590 600 610 pF1KB9 FNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNK :: ..:.:.:..: ::::: : .:: :.: :::::: .: :. ::: .:..:...::. CCDS55 FNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNS 580 590 600 610 620 630 620 630 640 650 660 670 pF1KB9 IKFVVKKPELVISYLP-PGMASKINTKALQ-SPKRPRSPGSNSKVPEIEVTVEGPNNNNP :.::.:.:::. . : : :. ....: :: : : :: ....: CCDS55 IQFVIKRPELLTEGVKEPIMDSQGTASSLGFSP--PALP------PE-------RDSGDP 640 650 660 670 680 690 700 710 720 730 pF1KB9 QTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQ .. .: .: . ...: ..: . :...:..:::.: :::::.: CCDS55 LVDE------------SLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKY 680 690 700 710 720 740 750 760 770 780 790 pF1KB9 AVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET :.::. ..: : . .:::: :.:::.: ::: ::.:: :::: . .: :. CCDS55 PVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP--FQG 730 740 750 760 770 780 800 810 820 830 840 850 pF1KB9 AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVN : :. :. .:: .::. ::. :::::. CCDS55 LI---------PK-----PD-------------------EDDANRLG--EKV-ILREQVK 790 800 860 870 880 890 900 910 pF1KB9 DLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSA .::..:.:::.:.. :: :::. : .: : : :.: . :. :. .: ...:: CCDS55 ELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAR 810 820 830 840 850 860 920 930 940 950 960 970 pF1KB9 EFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE CCDS55 EHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDS 870 880 890 900 910 920 >>CCDS64682.1 GTF2IRD2 gene_id:84163|Hs108|chr7 (108 aa) initn: 451 init1: 451 opt: 451 Z-score: 429.1 bits: 87.7 E(32554): 1.4e-17 Smith-Waterman score: 451; 88.8% identity (96.2% similar) in 80 aa overlap (1-80:1-80) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::.::::::.: :::.:::::::.::::::::::::::::::::::::::::::::: CCDS64 MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :: ::::.: ::::::.::: CCDS64 RGCAFVNARTDFQKDFAKYCRCFNFILCIPNLKRIAGKTSTVFSSKLS 70 80 90 100 >>CCDS47613.1 GTF2IRD1 gene_id:9569|Hs108|chr7 (944 aa) initn: 1286 init1: 355 opt: 355 Z-score: 326.7 bits: 71.8 E(32554): 7.1e-12 Smith-Waterman score: 1290; 32.6% identity (58.3% similar) in 926 aa overlap (22-910:30-849) 10 20 30 40 50 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYET ..: :.:::.:::. :.: .:::::.::.. CCDS47 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 10 20 30 40 50 60 60 70 80 90 100 pF1KB9 DVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQAN-------RMSVD ..::::::.:: :.:.::..:.::...: : : .. :.. ... : :.. CCDS47 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 -AVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPEN . .. ::: ::. : :..:::...:::.:::..::. . ..:::::::.::..: . CCDS47 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 YDLATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEP :: .: :::.. : : .::: :: ::: :. . : : : . CCDS47 YDPKALMAILEHSHRIRFKLKRP-LED----GGR----DSKALVELNGVSLIP-----KG 190 200 210 220 230 240 250 260 270 280 pF1KB9 TEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAE-DSTQHVPSET ..: : :. : : .. : . .. . .:. . . :. : : .::. CCDS47 SRDCG--LHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDL 230 240 250 260 270 280 290 300 310 320 330 pF1KB9 SED---PEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKR---KVREFNFEKWNAR . . :: ..: .: . ...: . : :. . ..:.:: .. . . :::.: CCDS47 GLSRPMPEPKATGAQDFSDCCGQKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAF 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB9 ITD------LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRP : . ::. :. ::. .::.:. : .:: . : . . :.:. :::.:: CCDS47 IKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRP 350 360 370 380 390 400 400 410 420 430 440 pF1KB9 STYGIPRLERILLAKERIRFVIKKH--ELL---NSTREDLQLDKPASGVKEEWYARITK- :::.:.:.::: .. :.:.::. : . :. .: .::: :. :.... CCDS47 CTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASP-PEDTSAEVSRA 410 420 430 440 450 460 450 460 470 480 490 pF1KB9 -LRKMVDQLFCKK--FAEALG-STEAKAVPYQKFEAHPNDLYV--EGLPENIPFRSPSWY . .. . : ..: : .: .. . .. .:.:: . .:. : CCDS47 TVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTD 470 480 490 500 510 520 500 510 520 530 540 550 pF1KB9 GIPRLEKIIQVGNRIKFVIKRPELLT-HSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEI ..: . : . :.:: .. .: ..:. . ::... . : :::::: . CCDS47 SMPGHLPSEDSGYGM-------EMLTDKGLSEDARPE-ERPVEDSHGDVIRPLRKQVELL 530 540 550 560 570 560 570 580 590 600 610 pF1KB9 FNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNK :: ..:.:.:..: ::::: : .:: :.: :::::: .: :. ::: .:..:...::. CCDS47 FNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNS 580 590 600 610 620 630 620 630 640 650 660 670 pF1KB9 IKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQT :.::.:.::: : :. : ..: .: .: : .. .. CCDS47 IQFVIKRPEL----LTEGVKEPI----MDSQER------DSGDPLVDESL---------- 640 650 660 680 690 700 710 720 730 pF1KB9 SAVRTPTQTNGSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAV : .: . ...: ..: . :...:..:::.: :::::.: : CCDS47 ----------------KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPV 670 680 690 700 710 740 750 760 770 780 790 pF1KB9 KVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAI .::. ..: : . .:::: :.:::.: ::: ::.:: :::: . .: :. : CCDS47 QVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP--FQGLI 720 730 740 750 760 770 800 810 820 830 840 850 pF1KB9 KESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDL :. :. .:: .::. ::. :::::..: CCDS47 ---------PK-----PD-------------------EDDANRLG--EKV-ILREQVKEL 780 790 860 870 880 890 900 910 pF1KB9 FSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEF :..:.:::.:.. :: :::. : .: : : :.: . :. :. .: ...:: CCDS47 FNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREH 800 810 820 830 840 850 920 930 940 950 960 970 pF1KB9 IKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPD CCDS47 VRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVA 860 870 880 890 900 910 978 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:58:47 2016 done: Thu Nov 3 22:58:48 2016 Total Scan time: 4.850 Total Display time: 0.330 Function used was FASTA [36.3.4 Apr, 2011]