FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9055, 978 aa 1>>>pF1KB9055 978 - 978 aa - 978 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3161+/-0.000397; mu= 12.6278+/- 0.025 mean_var=126.2661+/-26.544, 0's: 0 Z-trim(115.5): 22 B-trim: 914 in 1/57 Lambda= 0.114138 statistics sampled from 25992 (26014) to 25992 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.305), width: 16 Scan time: 11.340 The best scores are: opt bits E(85289) NP_127493 (OMIM: 601679) general transcription fac ( 978) 6456 1075.1 0 NP_001157108 (OMIM: 601679) general transcription ( 976) 6245 1040.4 0 NP_127494 (OMIM: 601679) general transcription fac ( 977) 6233 1038.4 0 NP_127492 (OMIM: 601679) general transcription fac ( 998) 4822 806.1 0 NP_001509 (OMIM: 601679) general transcription fac ( 957) 4587 767.4 0 NP_001267729 (OMIM: 601679) general transcription ( 274) 1777 304.3 5.5e-82 NP_775808 (OMIM: 608899) general transcription fac ( 949) 1588 273.5 3.6e-72 NP_001003795 (OMIM: 608900) general transcription ( 949) 1587 273.4 4.1e-72 XP_016868292 (OMIM: 604318) PREDICTED: general tra ( 959) 634 116.4 7.1e-25 NP_057412 (OMIM: 604318) general transcription fac ( 959) 624 114.8 2.2e-24 XP_016868291 (OMIM: 604318) PREDICTED: general tra ( 975) 624 114.8 2.3e-24 NP_001268376 (OMIM: 608899) general transcription ( 108) 451 85.8 1.4e-16 XP_011515015 (OMIM: 604318) PREDICTED: general tra ( 925) 355 70.5 4.7e-11 XP_016868294 (OMIM: 604318) PREDICTED: general tra ( 941) 355 70.5 4.7e-11 NP_005676 (OMIM: 604318) general transcription fac ( 944) 355 70.5 4.8e-11 XP_016868293 (OMIM: 604318) PREDICTED: general tra ( 944) 355 70.5 4.8e-11 XP_006716245 (OMIM: 604318) PREDICTED: general tra ( 960) 355 70.5 4.8e-11 XP_006716246 (OMIM: 604318) PREDICTED: general tra ( 960) 355 70.5 4.8e-11 NP_001186136 (OMIM: 604318) general transcription ( 976) 355 70.5 4.9e-11 >>NP_127493 (OMIM: 601679) general transcription factor (978 aa) initn: 6456 init1: 6456 opt: 6456 Z-score: 5748.6 bits: 1075.1 E(85289): 0 Smith-Waterman score: 6456; 100.0% identity (100.0% similar) in 978 aa overlap (1-978:1-978) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 910 920 930 940 950 960 970 pF1KB9 IKETDGSSQIKQEPDPTW :::::::::::::::::: NP_127 IKETDGSSQIKQEPDPTW 970 >>NP_001157108 (OMIM: 601679) general transcription fact (976 aa) initn: 4582 init1: 4582 opt: 6245 Z-score: 5560.8 bits: 1040.4 E(85289): 0 Smith-Waterman score: 6245; 97.1% identity (98.1% similar) in 978 aa overlap (1-978:1-976) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP ::::::::::::::: .... .: . : . : : :: .: :.:: ::::::: NP_001 EESEDPDYYQYNIQGPSETDDVDEKQPLSKPLQGS--HHSSEGNEGTEMEVPAEDDDYSP 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 600 610 620 630 640 650 670 680 690 700 710 720 pF1KB9 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 660 670 680 690 700 710 730 740 750 760 770 780 pF1KB9 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 720 730 740 750 760 770 790 800 810 820 830 840 pF1KB9 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 780 790 800 810 820 830 850 860 870 880 890 900 pF1KB9 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 840 850 860 870 880 890 910 920 930 940 950 960 pF1KB9 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 900 910 920 930 940 950 970 pF1KB9 IKETDGSSQIKQEPDPTW :::::::::::::::::: NP_001 IKETDGSSQIKQEPDPTW 960 970 >>NP_127494 (OMIM: 601679) general transcription factor (977 aa) initn: 6217 init1: 4582 opt: 6233 Z-score: 5550.1 bits: 1038.4 E(85289): 0 Smith-Waterman score: 6233; 97.0% identity (98.0% similar) in 979 aa overlap (1-978:1-977) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 EESEDPDYYQYNIQ-GSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYS :::::::::::::: : .... .: . : . : : :: .: :.:: :::::: NP_127 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGS--HHSSEGNEGTEMEVPAEDDDYS 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 PPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 PPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKA 300 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 KGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 KGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL 360 370 380 390 400 410 420 430 440 450 460 470 pF1KB9 NSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 NSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHP 420 430 440 450 460 470 480 490 500 510 520 530 pF1KB9 NDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 NDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTP 480 490 500 510 520 530 540 550 560 570 580 590 pF1KB9 VKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 VKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFR 540 550 560 570 580 590 600 610 620 630 640 650 pF1KB9 SPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 SPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNS 600 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 KVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 KVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVEN 660 670 680 690 700 710 720 730 740 750 760 770 pF1KB9 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA 720 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 KIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 KIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERL 780 790 800 810 820 830 840 850 860 870 880 890 pF1KB9 SKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 SKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPS 840 850 860 870 880 890 900 910 920 930 940 950 pF1KB9 YLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 YLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATE 900 910 920 930 940 950 960 970 pF1KB9 EIKETDGSSQIKQEPDPTW ::::::::::::::::::: NP_127 EIKETDGSSQIKQEPDPTW 960 970 >>NP_127492 (OMIM: 601679) general transcription factor (998 aa) initn: 4816 init1: 4816 opt: 4822 Z-score: 4294.3 bits: 806.1 E(85289): 0 Smith-Waterman score: 6406; 98.0% identity (98.0% similar) in 998 aa overlap (1-978:1-998) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 pF1KB9 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPAEDSTQHVP :::::::::::::: :::::::::::::::::::::::::: NP_127 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB9 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 310 320 330 340 350 360 350 360 370 380 390 400 pF1KB9 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 370 380 390 400 410 420 410 420 430 440 450 460 pF1KB9 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 430 440 450 460 470 480 470 480 490 500 510 520 pF1KB9 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 490 500 510 520 530 540 530 540 550 560 570 580 pF1KB9 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 550 560 570 580 590 600 590 600 610 620 630 640 pF1KB9 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 610 620 630 640 650 660 650 660 670 680 690 700 pF1KB9 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 670 680 690 700 710 720 710 720 730 740 750 760 pF1KB9 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 730 740 750 760 770 780 770 780 790 800 810 820 pF1KB9 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 790 800 810 820 830 840 830 840 850 860 870 880 pF1KB9 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 850 860 870 880 890 900 890 900 910 920 930 940 pF1KB9 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_127 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 910 920 930 940 950 960 950 960 970 pF1KB9 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW :::::::::::::::::::::::::::::::::::::: NP_127 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 970 980 990 >>NP_001509 (OMIM: 601679) general transcription factor (957 aa) initn: 4582 init1: 4582 opt: 4587 Z-score: 4085.4 bits: 767.4 E(85289): 0 Smith-Waterman score: 6271; 97.9% identity (97.9% similar) in 978 aa overlap (1-978:1-957) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP :::::::::::::::::::::::::::::::::: ::::: NP_001 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAED---------------------DDYSP 250 260 270 310 320 330 340 350 360 pF1KB9 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 280 290 300 310 320 330 370 380 390 400 410 420 pF1KB9 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 340 350 360 370 380 390 430 440 450 460 470 480 pF1KB9 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 400 410 420 430 440 450 490 500 510 520 530 540 pF1KB9 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 460 470 480 490 500 510 550 560 570 580 590 600 pF1KB9 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 520 530 540 550 560 570 610 620 630 640 650 660 pF1KB9 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 580 590 600 610 620 630 670 680 690 700 710 720 pF1KB9 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 640 650 660 670 680 690 730 740 750 760 770 780 pF1KB9 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 700 710 720 730 740 750 790 800 810 820 830 840 pF1KB9 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 760 770 780 790 800 810 850 860 870 880 890 900 pF1KB9 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 820 830 840 850 860 870 910 920 930 940 950 960 pF1KB9 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 880 890 900 910 920 930 970 pF1KB9 IKETDGSSQIKQEPDPTW :::::::::::::::::: NP_001 IKETDGSSQIKQEPDPTW 940 950 >>NP_001267729 (OMIM: 601679) general transcription fact (274 aa) initn: 1777 init1: 1777 opt: 1777 Z-score: 1592.9 bits: 304.3 E(85289): 5.5e-82 Smith-Waterman score: 1777; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP ::::::::::::::::::::::::::::::::: NP_001 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEG 250 260 270 310 320 330 340 350 360 pF1KB9 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK >>NP_775808 (OMIM: 608899) general transcription factor (949 aa) initn: 1904 init1: 934 opt: 1588 Z-score: 1416.6 bits: 273.5 E(85289): 3.6e-72 Smith-Waterman score: 1595; 45.5% identity (67.8% similar) in 653 aa overlap (1-642:1-629) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::.::::::.: :::.:::::::.::::::::::::::::::::::::::::::::: NP_775 MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :: ::::.: ::::::.:::: : . ..: .: :.: . : : :::.::::: NP_775 RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI ::::::::: ...::::::::::::::::::::::::::.:::::::::::::::::::: NP_775 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK ::::.:::: :....:: :::::.:::.::. :::::.::::: :::::::. ::.:: NP_775 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 180 190 200 210 220 230 250 260 270 280 290 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSET-SEDPEVEVTIEDDDYS .:::::.:::::.:::: :: .:: :::.: :::: :::: .::::.:: :: . : NP_775 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 PPSKRPKAN--ELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAI :. .: : : : .: : ..:: : .::.::..:: ::...:: NP_775 SSVTNSAAGVEDLNIVQVTVPDN---EKERLSSIEK----IKQLREQVNDLFSRKFGEAI 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 KAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKH- . :: .:: . . . ..:.: :. :. :. : ..::: : : :.:.. . NP_775 GVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 ---ELLNSTREDLQLDKPASGVKEEWYAR--ITKLRKMVDQLFCKKFAEALGSTEAKAVP :: : .. ..:. . .:.: ....... :.::. . .... NP_775 PGLELSNVGKR--KIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQ-SMSVSKEYNLRRH 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB9 YQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEV :: ... : :.: . :. . . . . . .:. .. ..... . NP_775 YQTNHSKHYDQYMERM------RDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSP-- 470 480 490 500 510 540 550 560 570 580 pF1KB9 TQPRTNTPVKEDWNVRITKLRKQVEEI--FNLKFAQALGLTEAVKVPYPVFESNPEFLYV :: ::.. . :::.... . ... . . ....... . . .: NP_775 TQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVS 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 EGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSP : : . .:. . : : . :. .. .:. . .: : : :.:.. : NP_775 EELLDTVPM-TGTKSGNEIFSRVEKSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLK 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 KRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAK NP_775 SRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLY 640 650 660 670 680 690 >>NP_001003795 (OMIM: 608900) general transcription fact (949 aa) initn: 1904 init1: 934 opt: 1587 Z-score: 1415.7 bits: 273.4 E(85289): 4.1e-72 Smith-Waterman score: 1590; 45.5% identity (67.8% similar) in 655 aa overlap (1-642:1-629) 10 20 30 40 50 60 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE :::::.::::::.: :::.:::::::.::::::::::::::::::::::::::::::::: NP_001 MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF :: ::::.: ::::::.:::: : . ..: .: :.: . : : :::.::::: NP_001 RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI ::::::::: ...::::::::::::::::::::::::::.:::::::::::::::::::: NP_001 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK ::::.:::: :....:: :::::.:::.::. :::::.::::: :::::::. ::.:: NP_001 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 180 190 200 210 220 230 250 260 270 280 290 pF1KB9 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSET-SEDPEVEVTIEDDDYS .:::::.:::::.:::: :: .:: :::.: :::: :::: .::::.:: :: . : NP_001 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB9 PPSKRPKAN--ELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAI :. .: : : : .: : ..:: : .::.::..:: ::...:: NP_001 SSVTNSAAGVEDLNIVQVTVPDN---EKERLSSIEK----IKQLREQVNDLFSRKFGEAI 300 310 320 330 340 360 370 380 390 400 410 pF1KB9 KAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKH- . :: .:: . . . ..:.: :. :. :. : ..::: : : :.:.. . NP_001 GVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPL 350 360 370 380 390 400 420 430 440 450 460 470 pF1KB9 ---ELLNSTREDLQLDKPASGVKEEWYAR--ITKLRKMVDQLFCKKFAEALGSTEAKAVP :: : .. ..:. . .:.: ....... :.::. . .... NP_001 PGLELSNVGKR--KIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQ-SMSVSKEYNLRRH 410 420 430 440 450 460 480 490 500 510 520 530 pF1KB9 YQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEV :: ... : :.: . :. . . . . . .:. .. ..... . NP_001 YQTNHSKHYDQYTERM------RDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSP-- 470 480 490 500 510 540 550 560 570 580 pF1KB9 TQPRTNTPVKEDWNVRITKLRKQVEEI--FNLKFAQALGLTEAVKVPYPVFESNPEFLYV :: ::.. . :::.... . ... . . ....... . . .: NP_001 TQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVS 520 530 540 550 560 570 590 600 610 620 630 640 pF1KB9 EGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELV--ISYLPPGMASKINTKALQ : : . .:. . : : . :. .. . :: .. .:: : :.:.. : NP_001 EELLDTVPM-TGTKSGNEIFLRVEKSLK--KFCINWSRLVSVASTGTPAMVDANNGLVTK 580 590 600 610 620 630 650 660 670 680 690 700 pF1KB9 SPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWN NP_001 LKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTL 640 650 660 670 680 690 >>XP_016868292 (OMIM: 604318) PREDICTED: general transcr (959 aa) initn: 1017 init1: 355 opt: 634 Z-score: 567.5 bits: 116.4 E(85289): 7.1e-25 Smith-Waterman score: 1293; 32.8% identity (58.0% similar) in 927 aa overlap (22-910:30-848) 10 20 30 40 50 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYET ..: :.:::.:::. :.: .:::::.::.. XP_016 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 10 20 30 40 50 60 60 70 80 90 100 pF1KB9 DVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQAN-------RMSVD ..::::::.:: :.:.::..:.::...: : : .. :.. ... : :.. XP_016 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 -AVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPEN . .. ::: ::. : :..:::...:::.:::..::. . ..:::::::.::..: . XP_016 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 YDLATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEP :: .: :::.. : : .::: :: ::: :. . : : : . XP_016 YDPKALMAILEHSHRIRFKLKRP-LED----GGR----DSKALVELNGVSLIP-----KG 190 200 210 220 230 240 250 260 270 280 pF1KB9 TEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAE-DSTQHVPSET ..: : :. : : .. : . .. . .:. . . :. : : .::. XP_016 SRDCG--LHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDL 230 240 250 260 270 280 290 300 310 320 330 pF1KB9 SED---PEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKR---KVREFNFEKWNAR . . :: ..: .: . ...: . : :. . ..:.:: .. . . :::.: XP_016 GLSRPMPEPKATGAQDFSDCCGQKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAF 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB9 ITD------LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRP : . ::. :. ::. .::.:. : .:: . : . . :.:. :::.:: XP_016 IKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRP 350 360 370 380 390 400 400 410 420 430 440 pF1KB9 STYGIPRLERILLAKERIRFVIKKH--ELL---NSTREDLQLDKPASGVKEEWYARITK- :::.:.:.::: .. :.:.::. : . :. .: .::: :. :.... XP_016 CTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASP-PEDTSAEVSRA 410 420 430 440 450 460 450 460 470 480 490 pF1KB9 -LRKMVDQLFCKK--FAEALG-STEAKAVPYQKFEAHPNDLYV--EGLPENIPFRSPSWY . .. . : ..: : .: .. . .. .:.:: . .:. : XP_016 TVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTD 470 480 490 500 510 520 500 510 520 530 540 550 pF1KB9 GIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIF ..: . : . :.:: : .: .: :::::: .: XP_016 SMPGHLPSEDSGYGM-------EMLTDSHGDVIRP----------------LRKQVELLF 530 540 550 560 570 580 590 600 610 pF1KB9 NLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKI : ..:.:.:..: ::::: : .:: :.: :::::: .: :. ::: .:..:...::.: XP_016 NTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSI 560 570 580 590 600 610 620 630 640 650 660 670 pF1KB9 KFVVKKPELVISYLP-PGMASKINTKALQ-SPKRPRSPGSNSKVPEIEVTVEGPNNNNPQ .::.:.:::. . : : :. ....: :: : : :: ....: XP_016 QFVIKRPELLTEGVKEPIMDSQGTASSLGFSP--PALP------PE-------RDSGDPL 620 630 640 650 660 680 690 700 710 720 730 pF1KB9 TSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQA .. .: .: . ...: ..: . :...:..:::.: :::::.: XP_016 VDE------------SLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYP 670 680 690 700 710 740 750 760 770 780 790 pF1KB9 VKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETA :.::. ..: : . .:::: :.:::.: ::: ::.:: :::: . .: :. XP_016 VQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP--FQGL 720 730 740 750 760 800 810 820 830 840 850 pF1KB9 IKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVND : :. :. .:: .::. ::. :::::.. XP_016 I---------PK-----PD-------------------EDDANRLG--EKV-ILREQVKE 770 780 790 860 870 880 890 900 910 pF1KB9 LFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAE ::..:.:::.:.. :: :::. : .: : : :.: . :. :. .: ...:: XP_016 LFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKARE 800 810 820 830 840 850 920 930 940 950 960 970 pF1KB9 FIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEP XP_016 HVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSV 860 870 880 890 900 910 >>NP_057412 (OMIM: 604318) general transcription factor (959 aa) initn: 1017 init1: 355 opt: 624 Z-score: 558.6 bits: 114.8 E(85289): 2.2e-24 Smith-Waterman score: 1318; 33.0% identity (59.2% similar) in 928 aa overlap (22-910:30-864) 10 20 30 40 50 pF1KB9 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYET ..: :.:::.:::. :.: .:::::.::.. NP_057 MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDE 10 20 30 40 50 60 60 70 80 90 100 pF1KB9 DVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQAN-------RMSVD ..::::::.:: :.:.::..:.::...: : : .. :.. ... : :.. NP_057 SAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLE 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB9 -AVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPEN . .. ::: ::. : :..:::...:::.:::..::. . ..:::::::.::..: . NP_057 HGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAE 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB9 YDLATLKWILENKAGISFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEP :: .: :::.. : : .::: :: ::: :. . : : : . NP_057 YDPKALMAILEHSHRIRFKLKRP-LED----GGR----DSKALVELNGVSLIP-----KG 190 200 210 220 230 240 250 260 270 280 pF1KB9 TEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAE-DSTQHVPSET ..: : :. : : .. : . .. . .:. . . :. : : .::. NP_057 SRDCG--LHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDL 230 240 250 260 270 280 290 300 310 320 330 pF1KB9 SED---PEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKR---KVREFNFEKWNAR . . :: ..: .: . ...: . : :. . ..:.:: .. . . :::.: NP_057 GLSRPMPEPKATGAQDFSDCCGQKPTG---PGGPLIQNVHASKRILFSIVHDKSEKWDAF 290 300 310 320 330 340 340 350 360 370 380 390 pF1KB9 ITD------LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRP : . ::. :. ::. .::.:. : .:: . : . . :.:. :::.:: NP_057 IKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRP 350 360 370 380 390 400 400 410 420 430 440 pF1KB9 STYGIPRLERILLAKERIRFVIKKH--ELL---NSTREDLQLDKPASGVKEEWYARITK- :::.:.:.::: .. :.:.::. : . :. .: .::: :. :.... NP_057 CTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASP-PEDTSAEVSRA 410 420 430 440 450 460 450 460 470 480 490 pF1KB9 -LRKMVDQLFCKK--FAEALG-STEAKAVPYQKFEAHPNDLYV--EGLPENIPFRSPSWY . .. . : ..: : .: .. . .. .:.:: . .:. : NP_057 TVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTD 470 480 490 500 510 520 500 510 520 530 540 550 pF1KB9 GIPRLEKIIQVGNRIKFVIKRPELLT-HSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEI ..: . : . :.:: .. .: ..:. . ::... . : :::::: . NP_057 SMPGHLPSEDSGYGM-------EMLTDKGLSEDARPE-ERPVEDSHGDVIRPLRKQVELL 530 540 550 560 570 560 570 580 590 600 610 pF1KB9 FNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNK :: ..:.:.:..: ::::: : .:: :.: :::::: .: :. ::: .:..:...::. NP_057 FNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNS 580 590 600 610 620 630 620 630 640 650 660 670 pF1KB9 IKFVVKKPELVISYLP-PGMASKINTKALQ-SPKRPRSPGSNSKVPEIEVTVEGPNNNNP :.::.:.:::. . : : :. ....: :: : : :: ....: NP_057 IQFVIKRPELLTEGVKEPIMDSQGTASSLGFSP--PALP------PE-------RDSGDP 640 650 660 670 680 690 700 710 720 730 pF1KB9 QTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQ .. .: .: . ...: ..: . :...:..:::.: :::::.: NP_057 LVDE------------SLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKY 680 690 700 710 720 740 750 760 770 780 790 pF1KB9 AVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFET :.::. ..: : . .:::: :.:::.: ::: ::.:: :::: . .: :. NP_057 PVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP--FQG 730 740 750 760 770 780 800 810 820 830 840 850 pF1KB9 AIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVN : :. :. .:: .::. ::. :::::. NP_057 LI---------PK-----PD-------------------EDDANRLG--EKV-ILREQVK 790 800 860 870 880 890 900 910 pF1KB9 DLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSA .::..:.:::.:.. :: :::. : .: : : :.: . :. :. .: ...:: NP_057 ELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAR 810 820 830 840 850 860 920 930 940 950 960 970 pF1KB9 EFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQE NP_057 EHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDS 870 880 890 900 910 920 978 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 22:58:48 2016 done: Thu Nov 3 22:58:50 2016 Total Scan time: 11.340 Total Display time: 0.310 Function used was FASTA [36.3.4 Apr, 2011]