Result of FASTA (ccds) for pF1KB9116
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9116, 772 aa
  1>>>pF1KB9116 772 - 772 aa - 772 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.2333+/-0.0011; mu= -2.1809+/- 0.064
 mean_var=364.0412+/-85.066, 0's: 0 Z-trim(111.3): 296  B-trim: 770 in 1/53
 Lambda= 0.067220
 statistics sampled from 11939 (12291) to 11939 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.378), width:  16
 Scan time:  3.480

The best scores are:                                      opt bits E(32554)
CCDS62283.1 TLK2 gene_id:11011|Hs108|chr17         ( 772) 5124 512.0 1.5e-144
CCDS82182.1 TLK2 gene_id:11011|Hs108|chr17         ( 601) 2553 262.5 1.4e-69
CCDS45753.1 TLK2 gene_id:11011|Hs108|chr17         ( 718) 2553 262.6 1.6e-69
CCDS11633.1 TLK2 gene_id:11011|Hs108|chr17         ( 750) 2553 262.6 1.7e-69
CCDS46448.1 TLK1 gene_id:9874|Hs108|chr2           ( 670) 2298 237.8 4.3e-62
CCDS46447.1 TLK1 gene_id:9874|Hs108|chr2           ( 718) 2298 237.9 4.5e-62
CCDS2241.1 TLK1 gene_id:9874|Hs108|chr2            ( 766) 2298 237.9 4.7e-62


>>CCDS62283.1 TLK2 gene_id:11011|Hs108|chr17              (772 aa)
 initn: 5124 init1: 5124 opt: 5124  Z-score: 2708.6  bits: 512.0 E(32554): 1.5e-144
Smith-Waterman score: 5124; 100.0% identity (100.0% similar) in 772 aa overlap (1-772:1-772)

               10        20        30        40        50        60
pF1KB9 MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 RNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 RNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 PRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 ANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 ANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 TVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 TVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 KQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 KQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEE
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAF
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB9 CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
              550       560       570       580       590       600

              610       620       630       640       650       660
pF1KB9 VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISN
              610       620       630       640       650       660

              670       680       690       700       710       720
pF1KB9 KVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 KVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRR
              670       680       690       700       710       720

              730       740       750       760       770  
pF1KB9 CLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS62 CLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
              730       740       750       760       770  

>>CCDS82182.1 TLK2 gene_id:11011|Hs108|chr17              (601 aa)
 initn: 2529 init1: 2529 opt: 2553  Z-score: 1362.5  bits: 262.5 E(32554): 1.4e-69
Smith-Waterman score: 3944; 96.5% identity (96.5% similar) in 623 aa overlap (150-772:1-601)

     120       130       140       150       160       170         
pF1KB9 LPRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQ
                                     ::::::::::::::::::::::::::::::
CCDS82                               MSVMLAKPRLDTEQLAQRGAGLCFTFVSAQ
                                             10        20        30

     180       190       200       210       220       230         
pF1KB9 QNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 QNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLL
               40        50        60        70        80        90

     240       250       260       270       280       290         
pF1KB9 RANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 RANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHF
              100       110       120       130       140       150

     300       310       320       330       340       350         
pF1KB9 TTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 TTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNE
              160       170       180       190       200       210

     360       370       380       390       400       410         
pF1KB9 QKQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKE
       :::::::::::::::                      :::::::::::::::::::::::
CCDS82 QKQRKSKTNGAENET----------------------LTLAEYHEQEEIFKLRLGHLKKE
              220                             230       240        

     420       430       440       450       460       470         
pF1KB9 EAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 EAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKA
      250       260       270       280       290       300        

     480       490       500       510       520       530         
pF1KB9 FDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDS
      310       320       330       340       350       360        

     540       550       560       570       580       590         
pF1KB9 FCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 FCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNIL
      370       380       390       400       410       420        

     600       610       620       630       640       650         
pF1KB9 LVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKIS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 LVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKIS
      430       440       450       460       470       480        

     660       670       680       690       700       710         
pF1KB9 NKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 NKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIR
      490       500       510       520       530       540        

     720       730       740       750       760       770  
pF1KB9 RCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
       :::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 RCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
      550       560       570       580       590       600 

>>CCDS45753.1 TLK2 gene_id:11011|Hs108|chr17              (718 aa)
 initn: 3103 init1: 2529 opt: 2553  Z-score: 1361.5  bits: 262.6 E(32554): 1.6e-69
Smith-Waterman score: 4633; 93.0% identity (93.0% similar) in 772 aa overlap (1-772:1-718)

               10        20        30        40        50        60
pF1KB9 MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 RNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPL
       :::::::::::::::::::::::::::::                               
CCDS45 RNRKRKAEPYETSQGKGTPRGHKISDYFE-------------------------------
               70        80                                        

              130       140       150       160       170       180
pF1KB9 PRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
        :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 -RRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
       90       100       110       120       130       140        

              190       200       210       220       230       240
pF1KB9 NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLR
      150       160       170       180       190       200        

              250       260       270       280       290       300
pF1KB9 ANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 ANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFT
      210       220       230       240       250       260        

              310       320       330       340       350       360
pF1KB9 TVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
      270       280       290       300       310       320        

              370       380       390       400       410       420
pF1KB9 KQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEE
       ::::::::::::::                      ::::::::::::::::::::::::
CCDS45 KQRKSKTNGAENET----------------------LTLAEYHEQEEIFKLRLGHLKKEE
      330       340                             350       360      

              430       440       450       460       470       480
pF1KB9 AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAF
        370       380       390       400       410       420      

              490       500       510       520       530       540
pF1KB9 DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
        430       440       450       460       470       480      

              550       560       570       580       590       600
pF1KB9 CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
        490       500       510       520       530       540      

              610       620       630       640       650       660
pF1KB9 VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISN
        550       560       570       580       590       600      

              670       680       690       700       710       720
pF1KB9 KVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRR
        610       620       630       640       650       660      

              730       740       750       760       770  
pF1KB9 CLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 CLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
        670       680       690       700       710        

>>CCDS11633.1 TLK2 gene_id:11011|Hs108|chr17              (750 aa)
 initn: 2529 init1: 2529 opt: 2553  Z-score: 1361.3  bits: 262.6 E(32554): 1.7e-69
Smith-Waterman score: 4930; 97.2% identity (97.2% similar) in 772 aa overlap (1-772:1-750)

               10        20        30        40        50        60
pF1KB9 MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MMEELHSLDPRRQELLEARFTGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 RNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RNRKRKAEPYETSQGKGTPRGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 PRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 ANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 TVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKRKPPAMGQAPPATNEQ
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 KQRKSKTNGAENETPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEE
       ::::::::::::::                      ::::::::::::::::::::::::
CCDS11 KQRKSKTNGAENET----------------------LTLAEYHEQEEIFKLRLGHLKKEE
              370                             380       390        

              430       440       450       460       470       480
pF1KB9 AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAF
      400       410       420       430       440       450        

              490       500       510       520       530       540
pF1KB9 DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSF
      460       470       480       490       500       510        

              550       560       570       580       590       600
pF1KB9 CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILL
      520       530       540       550       560       570        

              610       620       630       640       650       660
pF1KB9 VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISN
      580       590       600       610       620       630        

              670       680       690       700       710       720
pF1KB9 KVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRR
      640       650       660       670       680       690        

              730       740       750       760       770  
pF1KB9 CLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN
      700       710       720       730       740       750

>>CCDS46448.1 TLK1 gene_id:9874|Hs108|chr2                (670 aa)
 initn: 3202 init1: 1487 opt: 2298  Z-score: 1228.2  bits: 237.8 E(32554): 4.3e-62
Smith-Waterman score: 3253; 71.6% identity (82.6% similar) in 725 aa overlap (51-769:14-666)

               30        40        50        60         70         
pF1KB9 TGVGVSKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAEPY-ETSQGKGT
                                     .::::::... :.::::::   :.::::. 
CCDS46                  MAVLFLYDLKTTGKTPEKKQSESSRGRKRKAENQNESSQGKSI
                                10        20        30        40   

        80        90       100       110       120       130       
pF1KB9 P-RGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGLDGSAAK
         ::::::::::. ::.  :.:: :..::. :: ::.: :.  :    .:          
CCDS46 GGRGHKISDYFEYQGGN--GSSPVRGIPPAIRS-PQNSHSHSTPSSSVRP----------
            50        60          70         80        90          

       140       150       160       170       180       190       
pF1KB9 EATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSS
                                                  :::: :. .  .:   .
CCDS46 -------------------------------------------NSPSPTALAFGDHPIVQ
                                                         100       

       200       210       220       230       240       250       
pF1KB9 QKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKMLE
        ::.:.  .  :.:::. :..:::..: .::::::::::::::::::::::::::::.::
CCDS46 PKQLSF--KIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKLLE
       110         120       130       140       150       160     

       260       270       280       290       300       310       
pF1KB9 KYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGYA
       :::::::.:..:::::::::: :::.. :.::::::::::::::::::::::::::::.:
CCDS46 KYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGFA
         170       180       190       200       210       220     

       320       330       340       350         360        370    
pF1KB9 FQNLIKQQERINSQREEIERQRKMLAKRKPPAMG--QAPPATNEQKQRKSKT-NGAENET
       ::::.:::: .:.:::.::::::.:::::::. .  ::: ...: ::::.:. :::::. 
CCDS46 FQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAEND-
         230       240       250       260       270       280     

          380       390       400       410       420       430    
pF1KB9 PSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVR
       :      .. . : :       ::::::::::::::::::::::::::::::::::::::
CCDS46 P-----FVRPNLPQL-------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERVR
               290              300       310       320       330  

          440       450       460       470       480       490    
pF1KB9 NLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQ
       ::::::::::.::::::::::::::.:::::::::::::::::::::: ::::.::::::
CCDS46 NLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQ
            340       350       360       370       380       390  

          500       510       520       530       540       550    
pF1KB9 LNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDF
       :::.::::::::::::::::::::::::::::::::::::::::.:::::::::::::::
CCDS46 LNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDF
            400       410       420       430       440       450  

          560       570       580       590       600       610    
pF1KB9 YLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITDF
       ::::::::::::::::.:::::::.::::::::::::::::::::::.::::::::::::
CCDS46 YLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITDF
            460       470       480       490       500       510  

          620       630       640       650       660       670    
pF1KB9 GLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQC
       :::::::::::. ::::.:::::::::::::::::::::::::::::::::::::::.::
CCDS46 GLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQC
            520        530       540       550       560       570 

          680       690       700       710       720       730    
pF1KB9 LYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQ
       ::::::::::::::::::::::::::::::: ::::. :::::::::::::::::.::.:
CCDS46 LYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQ
             580       590       600       610       620       630 

          740       750       760       770   
pF1KB9 LACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN 
       :: :::::::.:.: :...   :.....    ..:    
CCDS46 LANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
             640       650       660       670

>>CCDS46447.1 TLK1 gene_id:9874|Hs108|chr2                (718 aa)
 initn: 3342 init1: 1487 opt: 2298  Z-score: 1227.9  bits: 237.9 E(32554): 4.5e-62
Smith-Waterman score: 3448; 70.7% identity (81.8% similar) in 786 aa overlap (2-769:1-714)

               10        20                    30        40        
pF1KB9 MMEELHSLDPRRQELLEARFTGVGV------------SKGPLNSESSNQSLCSVGSLSDK
        :.::::::::::::::::::::.             .:.  :.::::.:. :.::::::
CCDS46  MDELHSLDPRRQELLEARFTGVASGSTGSTGSCSVGAKASTNNESSNHSFGSLGSLSDK
                10        20        30        40        50         

       50        60         70          80        90       100     
pF1KB9 EVETPEKKQNDQ-RNRKRKAEPY-ETSQGKGTP-RGHKISDYFEFAGGSAPGTSPGRSVP
       : :::::::... :.::::::   :.::::.   ::::::::::. ::.  :.:: :..:
CCDS46 ESETPEKKQSESSRGRKRKAENQNESSQGKSIGGRGHKISDYFEYQGGN--GSSPVRGIP
      60        70        80        90       100         110       

         110       120       130       140       150       160     
pF1KB9 PVARSSPQHSLSNPLPRRVEQPLYGLDGSAAKEATEEQSALPTLMSVMLAKPRLDTEQLA
       :. :: ::.: :.  :    .:                                      
CCDS46 PAIRS-PQNSHSHSTPSSSVRP--------------------------------------
       120        130                                              

         170       180       190       200       210       220     
pF1KB9 QRGAGLCFTFVSAQQNSPSSTGSGNTEHSCSSQKQISIQHRQTQSDLTIEKISALENSKN
                      :::: :. .  .:   . ::.:.  .  :.:::. :..:::..: 
CCDS46 ---------------NSPSPTALAFGDHPIVQPKQLSF--KIIQTDLTMLKLAALESNKI
                     140       150       160         170       180 

         230       240       250       260       270       280     
pF1KB9 SDLEKKEGRIDDLLRANCDLRRQIDEQQKMLEKYKERLNRCVTMSKKLLIEKSKQEKMAC
       .::::::::::::::::::::::::::::.:::::::::.:..:::::::::: :::.. 
CCDS46 QDLEKKEGRIDDLLRANCDLRRQIDEQQKLLEKYKERLNKCISMSKKLLIEKSTQEKLSS
             190       200       210       220       230       240 

         290       300       310       320       330       340     
pF1KB9 RDKSMQDRLRLGHFTTVRHGASFTEQWTDGYAFQNLIKQQERINSQREEIERQRKMLAKR
       :.::::::::::::::::::::::::::::.:::::.:::: .:.:::.::::::.::::
CCDS46 REKSMQDRLRLGHFTTVRHGASFTEQWTDGFAFQNLVKQQEWVNQQREDIERQRKLLAKR
             250       260       270       280       290       300 

         350         360        370       380       390       400  
pF1KB9 KPPAMG--QAPPATNEQKQRKSKT-NGAENETPSSGNTELKDTAPALGAHSLLRLTLAEY
       :::. .  ::: ...: ::::.:. :::::. :      .. . : :       ::::::
CCDS46 KPPTANNSQAPSTNSEPKQRKNKAVNGAEND-PF-----VRPNLPQL-------LTLAEY
             310       320       330             340               

            410       420       430       440       450       460  
pF1KB9 HEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRIHNEDNSQFKDHPTLNDRY
       ::::::::::::::::::::::::::::::::::::::::::.::::::::::::::.::
CCDS46 HEQEEIFKLRLGHLKKEEAEIQAELERLERVRNLHIRELKRINNEDNSQFKDHPTLNERY
      350       360       370       380       390       400        

            470       480       490       500       510       520  
pF1KB9 LLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKELD
       :::::::::::::::::::: ::::.:::::::::.::::::::::::::::::::::::
CCDS46 LLLHLLGRGGFSEVYKAFDLYEQRYAAVKIHQLNKSWRDEKKENYHKHACREYRIHKELD
      410       420       430       440       450       460        

            530       540       550       560       570       580  
pF1KB9 HPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYLN
       ::::::::::::::::.:::::::::::::::::::::::::::::::.:::::::.:::
CCDS46 HPRIVKLYDYFSLDTDTFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIVMQIVNALRYLN
      470       480       490       500       510       520        

            590       600       610       620       630       640  
pF1KB9 EIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTYW
       :::::::::::::::::::.:::::::::::::::::::::::. ::::.::::::::::
CCDS46 EIKPPIIHYDLKPGNILLVDGTACGEIKITDFGLSKIMDDDSYG-VDGMDLTSQGAGTYW
      530       540       550       560       570        580       

            650       660       670       680       690       700  
pF1KB9 YLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATEV
       :::::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS46 YLPPECFVVGKEPPKISNKVDVWSVGVIFFQCLYGRKPFGHNQSQQDILQENTILKATEV
       590       600       610       620       630       640       

            710       720       730       740       750       760  
pF1KB9 QFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYLLPHIRKSVSTSSPAGAAIAST
       ::: ::::. :::::::::::::::::.::.::: :::::::.:.: :...   :.....
CCDS46 QFPVKPVVSSEAKAFIRRCLAYRKEDRFDVHQLANDPYLLPHMRRSNSSGNLHMAGLTAS
       650       660       670       680       690       700       

            770   
pF1KB9 SGASNNSSSN 
           ..:    
CCDS46 PTPPSSSIITY
       710        

>>CCDS2241.1 TLK1 gene_id:9874|Hs108|chr2                 (766 aa)
 initn: 3342 init1: 1487 opt: 2298  Z-score: 1227.5  bits: 237.9 E(32554): 4.7e-62
Smith-Waterman score: 3448; 70.7% identity (81.8% similar) in 786 aa overlap (2-769:49-762)

                                            10        20           
pF1KB9                              MMEELHSLDPRRQELLEARFTGVGV------
                                     :.::::::::::::::::::::.       
CCDS22 LSTSPTPGSAAAARSLLNHTPPSGRPREGAMDELHSLDPRRQELLEARFTGVASGSTGST
       20        30        40        50        60        70        

                30        40        50        60         70        
pF1KB9 ------SKGPLNSESSNQSLCSVGSLSDKEVETPEKKQNDQ-RNRKRKAEPY-ETSQGKG
             .:.  :.::::.:. :.::::::: :::::::... :.::::::   :.::::.
CCDS22 GSCSVGAKASTNNESSNHSFGSLGSLSDKESETPEKKQSESSRGRKRKAENQNESSQGKS
       80        90       100       110       120       130        

         80        90       100       110       120       130      
pF1KB9 TP-RGHKISDYFEFAGGSAPGTSPGRSVPPVARSSPQHSLSNPLPRRVEQPLYGLDGSAA
          ::::::::::. ::.  :.:: :..::. :: ::.: :.  :    .:         
CCDS22 IGGRGHKISDYFEYQGGN--GSSPVRGIPPAIRS-PQNSHSHSTPSSSVRP---------
      140       150         160       170        180               

        140       150       160       170       180       190      
pF1KB9 KEATEEQSALPTLMSVMLAKPRLDTEQLAQRGAGLCFTFVSAQQNSPSSTGSGNTEHSCS
                                                   :::: :. .  .:   
CCDS22 --------------------------------------------NSPSPTALAFGDHPIV
                                                    190       200  

        200       210       220       230       240       250      
pF1KB9 SQKQISIQHRQTQSDLTIEKISALENSKNSDLEKKEGRIDDLLRANCDLRRQIDEQQKML
       . ::.:.  .  :.:::. :..:::..: .::::::::::::::::::::::::::::.:
CCDS22 QPKQLSF--KIIQTDLTMLKLAALESNKIQDLEKKEGRIDDLLRANCDLRRQIDEQQKLL
              210       220       230       240       250       260

        260       270       280       290       300       310      
pF1KB9 EKYKERLNRCVTMSKKLLIEKSKQEKMACRDKSMQDRLRLGHFTTVRHGASFTEQWTDGY
       ::::::::.:..:::::::::: :::.. :.::::::::::::::::::::::::::::.
CCDS22 EKYKERLNKCISMSKKLLIEKSTQEKLSSREKSMQDRLRLGHFTTVRHGASFTEQWTDGF
              270       280       290       300       310       320

        320       330       340       350         360        370   
pF1KB9 AFQNLIKQQERINSQREEIERQRKMLAKRKPPAMG--QAPPATNEQKQRKSKT-NGAENE
       :::::.:::: .:.:::.::::::.:::::::. .  ::: ...: ::::.:. :::::.
CCDS22 AFQNLVKQQEWVNQQREDIERQRKLLAKRKPPTANNSQAPSTNSEPKQRKNKAVNGAEND
              330       340       350       360       370       380

           380       390       400       410       420       430   
pF1KB9 TPSSGNTELKDTAPALGAHSLLRLTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
        :      .. . : :       :::::::::::::::::::::::::::::::::::::
CCDS22 -PF-----VRPNLPQL-------LTLAEYHEQEEIFKLRLGHLKKEEAEIQAELERLERV
                    390              400       410       420       

           440       450       460       470       480       490   
pF1KB9 RNLHIRELKRIHNEDNSQFKDHPTLNDRYLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIH
       :::::::::::.::::::::::::::.:::::::::::::::::::::: ::::.:::::
CCDS22 RNLHIRELKRINNEDNSQFKDHPTLNERYLLLHLLGRGGFSEVYKAFDLYEQRYAAVKIH
       430       440       450       460       470       480       

           500       510       520       530       540       550   
pF1KB9 QLNKNWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLD
       ::::.::::::::::::::::::::::::::::::::::::::::.::::::::::::::
CCDS22 QLNKSWRDEKKENYHKHACREYRIHKELDHPRIVKLYDYFSLDTDTFCTVLEYCEGNDLD
       490       500       510       520       530       540       

           560       570       580       590       600       610   
pF1KB9 FYLKQHKLMSEKEARSIIMQIVNALKYLNEIKPPIIHYDLKPGNILLVNGTACGEIKITD
       :::::::::::::::::.:::::::.::::::::::::::::::::::.:::::::::::
CCDS22 FYLKQHKLMSEKEARSIVMQIVNALRYLNEIKPPIIHYDLKPGNILLVDGTACGEIKITD
       550       560       570       580       590       600       

           620       630       640       650       660       670   
pF1KB9 FGLSKIMDDDSYNSVDGMELTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFYQ
       ::::::::::::. ::::.:::::::::::::::::::::::::::::::::::::::.:
CCDS22 FGLSKIMDDDSYG-VDGMDLTSQGAGTYWYLPPECFVVGKEPPKISNKVDVWSVGVIFFQ
       610       620        630       640       650       660      

           680       690       700       710       720       730   
pF1KB9 CLYGRKPFGHNQSQQDILQENTILKATEVQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQ
       :::::::::::::::::::::::::::::::: ::::. :::::::::::::::::.::.
CCDS22 CLYGRKPFGHNQSQQDILQENTILKATEVQFPVKPVVSSEAKAFIRRCLAYRKEDRFDVH
        670       680       690       700       710       720      

           740       750       760       770   
pF1KB9 QLACDPYLLPHIRKSVSTSSPAGAAIASTSGASNNSSSN 
       ::: :::::::.:.: :...   :.....    ..:    
CCDS22 QLANDPYLLPHMRRSNSSGNLHMAGLTASPTPPSSSIITY
        730       740       750       760      




772 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 23:22:53 2016 done: Sat Nov  5 23:22:53 2016
 Total Scan time:  3.480 Total Display time:  0.160

Function used was FASTA [36.3.4 Apr, 2011]
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