Result of FASTA (omim) for
pF1KB9123
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9123, 505 aa
1>>>pF1KB9123 505 - 505 aa - 505 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.6243+/-0.000534; mu= -24.4549+/- 0.034
mean_var=1000.7394+/-205.930, 0's: 0 Z-trim(125.8): 150 B-trim: 0 in 0/62
Lambda= 0.040543
statistics sampled from 50082 (50287) to 50082 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.821), E-opt: 0.2 (0.59), width: 16
Scan time: 12.720
The best scores are: opt bits E(85289)
NP_003932 (OMIM: 605056) neural Wiskott-Aldrich sy ( 505) 3600 225.9 2.2e-58
NP_000368 (OMIM: 300299,300392,313900) wiskott-Ald ( 502) 863 65.8 3.4e-10
XP_016885275 (OMIM: 300299,300392,313900) PREDICTE ( 590) 863 65.9 3.8e-10
XP_011542279 (OMIM: 300299,300392,313900) PREDICTE ( 450) 724 57.6 9e-08
NP_008921 (OMIM: 605875) wiskott-Aldrich syndrome ( 498) 489 43.9 0.0013
XP_016857330 (OMIM: 606373,616193) PREDICTED: form (1102) 498 44.8 0.0015
XP_016857329 (OMIM: 606373,616193) PREDICTED: form (1102) 498 44.8 0.0015
XP_016857328 (OMIM: 606373,616193) PREDICTED: form (1159) 498 44.9 0.0016
XP_011542539 (OMIM: 606373,616193) PREDICTED: form (1360) 498 44.9 0.0017
XP_016857327 (OMIM: 606373,616193) PREDICTED: form (1384) 498 45.0 0.0017
XP_016857326 (OMIM: 606373,616193) PREDICTED: form (1417) 498 45.0 0.0018
NP_064450 (OMIM: 606373,616193) formin-2 isoform 2 (1722) 498 45.1 0.002
NP_001292353 (OMIM: 606373,616193) formin-2 isofor (1726) 498 45.1 0.002
>>NP_003932 (OMIM: 605056) neural Wiskott-Aldrich syndro (505 aa)
initn: 3600 init1: 3600 opt: 3600 Z-score: 1169.1 bits: 225.9 E(85289): 2.2e-58
Smith-Waterman score: 3600; 100.0% identity (100.0% similar) in 505 aa overlap (1-505:1-505)
10 20 30 40 50 60
pF1KB9 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAADRNCMWSKK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 CSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNLPMATVDIKNPEITTNRFYGPQVN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVGALMEVMQKRSK
430 440 450 460 470 480
490 500
pF1KB9 AIHSSDEDEDEDDEEDFEDDDEWED
:::::::::::::::::::::::::
NP_003 AIHSSDEDEDEDDEEDFEDDDEWED
490 500
>>NP_000368 (OMIM: 300299,300392,313900) wiskott-Aldrich (502 aa)
initn: 1526 init1: 606 opt: 863 Z-score: 303.9 bits: 65.8 E(85289): 3.4e-10
Smith-Waterman score: 1574; 48.7% identity (66.8% similar) in 536 aa overlap (11-505:16-502)
10 20 30 40 50
pF1KB9 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DR
: :. : :: .::. :: .::.::.:...:::::: :
NP_000 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 NCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGD
:.:. :..:.::::::.:::.:.. .. :.::::::::...::..: .:::::::
NP_000 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
70 80 90 100 110 120
120 130 140 150
pF1KB9 TCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRD----------------------
::..::::.:.::. :: : . . .: ::.: ::.
NP_000 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
130 140 150 160 170 180
160 170 180 190 200
pF1KB9 -------PPNGP-NLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKAD
:: :: .: .:::::.::.::..:. : . . : . .:..:: :...:::
NP_000 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGK---KKISKAD
190 200 210 220 230
210 220 230 240 250 260
pF1KB9 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT
::.::.:.:..::::::..:::.:::::.:..::. ::::::: : ::::.::::::
NP_000 IGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQ
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB9 GGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA
::.:::..:.::: : ::::::::: : :: ... .::..: :: .: .
NP_000 GGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGN------KGRSGPLPP---VPLG
300 310 320 330 340
330 340 350 360 370 380
pF1KB9 APPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP
:::: : ::::.: ::::: :... ::: :::: : :: ::::::::
NP_000 IAPPPPTPR-----GPPPPGRGGPPPPPP-PATGRSGPLPPPPPGAG-GPPMPPPPPPPP
350 360 370 380 390 400
390 400 410 420 430
pF1KB9 PPP----GPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDA
::: :: ::: :. :: ::. : :. :: :
NP_000 PPPSSGNGPAPPPLPPA----LVP--AGGLAP-------GG---------------GRGA
410 420 430
440 450 460 470 480 490
pF1KB9 LLDQIRQGIQLKSVADGQESTPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDE
:::::::::::... . ::. : : : :.:::::.::::::.::::::: ::. .
NP_000 LLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGD
440 450 460 470 480 490
500
pF1KB9 EDFEDDDEWED
:: .::::.:
NP_000 ED--EDDEWDD
500
>>XP_016885275 (OMIM: 300299,300392,313900) PREDICTED: w (590 aa)
initn: 1299 init1: 614 opt: 863 Z-score: 303.1 bits: 65.9 E(85289): 3.8e-10
Smith-Waterman score: 1497; 48.4% identity (66.5% similar) in 516 aa overlap (11-485:16-484)
10 20 30 40 50
pF1KB9 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DR
: :. : :: .::. :: .::.::.:...:::::: :
XP_016 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 NCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGD
:.:. :..:.::::::.:::.:.. .. :.::::::::...::..: .:::::::
XP_016 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
70 80 90 100 110 120
120 130 140 150
pF1KB9 TCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRD----------------------
::..::::.:.::. :: : . . .: ::.: ::.
XP_016 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
130 140 150 160 170 180
160 170 180 190 200
pF1KB9 -------PPNGP-NLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKAD
:: :: .: .:::::.::.::..:. : . . : . .:..: ::...:::
XP_016 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSG---KKKISKAD
190 200 210 220 230
210 220 230 240 250 260
pF1KB9 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT
::.::.:.:..::::::..:::.:::::.:..::. ::::::: : ::::.::::::
XP_016 IGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQ
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB9 GGVEAVKNELRRQAP--PPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTA
::.:::..:.::: : ::::::::: : :: ... .::..: :: .: .
XP_016 GGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGN------KGRSGPLPP---VPLG
300 310 320 330 340
330 340 350 360 370 380
pF1KB9 APPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPP
:::: : ::::.: ::::: :... ::: :::: : :: ::::::::
XP_016 IAPPPPTPRG-----PPPPGRGGPPPPPP-PATGRSGPLPPPPPGAG-GPPMPPPPPPPP
350 360 370 380 390 400
390 400 410 420 430
pF1KB9 PPP----GPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDA
::: :: ::: :. :: ::. : :. :: :
XP_016 PPPSSGNGPAPPPLPPA----LVP--AGGLAP-------GG---------------GRGA
410 420 430
440 450 460 470 480 490
pF1KB9 LLDQIRQGIQLKSVADGQESTPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDE
:::::::::::... . ::. : : : :.:::::.::::::.:::::
XP_016 LLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSGSRSVSQAG
440 450 460 470 480 490
500
pF1KB9 EDFEDDDEWED
XP_016 VQWCNHGSVQPQPPRLKRSSRLSSQSSWDYRRVPPYLANFWCFFGSDELSLPSSHYSHVA
500 510 520 530 540 550
>>XP_011542279 (OMIM: 300299,300392,313900) PREDICTED: w (450 aa)
initn: 1515 init1: 484 opt: 724 Z-score: 260.5 bits: 57.6 E(85289): 9e-08
Smith-Waterman score: 1346; 45.2% identity (61.6% similar) in 531 aa overlap (11-505:16-450)
10 20 30 40 50
pF1KB9 MSSVQQQPPPPRRVTNVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DR
: :. : :: .::. :: .::.::.:...:::::: :
XP_011 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 NCMWSKKCSGVACLVKDNPQRSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGD
:.:. :..:.::::::.:::.:.. .. :.::::::::...::..: .:::::::
XP_011 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
70 80 90 100 110 120
120 130 140 150
pF1KB9 TCQVALNFANEEEAKKFRKAVTDLLGRR-QRKSEKRRD----------------------
::..::::.:.::. :: : . . .: ::.: ::.
XP_011 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
130 140 150 160 170 180
160 170 180 190 200
pF1KB9 -------PPNGP-NLPMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKAD
:: :: .: .:::::.::.::..:. : . . : . .:..:: :...:::
XP_011 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGK---KKISKAD
190 200 210 220 230
210 220 230 240 250 260
pF1KB9 IGTPSNFQHIGHVGWDPNTGFDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKT
::.::.:.:..::::::..:::.:::::.:..::. ::::::: : ::::.::::::
XP_011 IGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQ
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB9 GGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAP-PPPPSRAPTAA
::.:::..:.:::. :::::::::: : ::..: :::: : :.
XP_011 GGLEAVRQEMRRQG-------RGGPPPPPPP----------ATGRSGPLPPPP---PGAG
300 310 320 330
330 340 350 360 370 380
pF1KB9 PPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPP
:: .::::: ::::::: : :: :::: ::
XP_011 GPP---------MPPPPP------------------PPPPPPSS-GNGP-APPPLPPALV
340 350 360
390 400 410 420 430 440
pF1KB9 PPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQI
: : : : :: ::::::
XP_011 PAGGLAPGG------------------------------------------GRGALLDQI
370 380
450 460 470 480 490
pF1KB9 RQGIQLKSVADGQESTPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFED
::::::... . ::. : : : :.:::::.::::::.::::::: ::. .:: .
XP_011 RQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDED--E
390 400 410 420 430 440
500
pF1KB9 DDEWED
::::.:
XP_011 DDEWDD
450
>>NP_008921 (OMIM: 605875) wiskott-Aldrich syndrome prot (498 aa)
initn: 342 init1: 342 opt: 489 Z-score: 185.8 bits: 43.9 E(85289): 0.0013
Smith-Waterman score: 561; 29.9% identity (52.2% similar) in 385 aa overlap (128-505:162-498)
100 110 120 130 140 150
pF1KB9 FVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKAVTDLLGRRQRKSEKRRDPPNGPNL
.:. . . :.. ..... ....: :: :.
NP_008 PLNNLTPYRDDGKEALKFYTDPSYFFDLWKEKMLQDTKDIMKEKRKHRKEKKDNPNRGNV
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB9 PMATVDIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGW
. .. : .. : . . ..::: .. :. . :. . ... ..
NP_008 NPRKIKTRKEEWEKMKM-GQE---FVESKEKLGTSGYPPTLVYQN-GSIGCVENVDASSY
200 210 220 230 240
220 230 240 250 260 270
pF1KB9 DPNTGFD-LNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTG-GVEAVK-NELRR
: : .. .: . :: .: .. : .. : :. . : . .
NP_008 PPPPQSDSASSPSPSF---------SEDNLPP-PPAEFSYPVDNQRGSGLAGPKRSSVVS
250 260 270 280 290
280 290 300 310 320 330
pF1KB9 QAPPPPPPSRGGPPPPPP---PPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPS
. ::: : :.:: : : :: ::::: : ::::: . . ::::: ::
NP_008 PSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMI--GIPPPPPPVGFGSPGTPPPPSPPS
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB9 VAVPPPPPNRMYPPPPPALPSSA-PSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPG
:: :. ::::: :.. :. :::: . : . ::::::::::::::::
NP_008 F---PPHPDFAAPPPPPPPPAADYPTLPPPPLSQPTG----GAPPPPPPPPPPGPPPPPF
360 370 380 390 400
400 410 420 430 440 450
pF1KB9 LPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSV
.::. .: : : . ..: :. ..:. ::. ::::.::. :
NP_008 TGADGQPAIPPP------LSDTTKP--------KSSLPAVSDARSDLLSAIRQGFQLRRV
410 420 430 440 450
460 470 480 490 500
pF1KB9 ADGQESTPPTPAPTSGIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED
. .:. .:: . .. .: :.. :: .::: .: :.:.: :
NP_008 EEQREQE------KRDVVGNDVATILSRRIAVEYSD---SEDDSSEF-DEDDWSD
460 470 480 490
>>XP_016857330 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 376 init1: 376 opt: 498 Z-score: 184.7 bits: 44.8 E(85289): 0.0015
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:356-553)
250 260 270 280 290 300
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
::::: .: ::::: : . ::::: :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
330 340 350 360 370 380
310 320 330 340 350
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
: ::::: : :. ::::: :....::::: . ::::: ::... : ::
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
390 400 410 420 430 440
360 370 380 390 400
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
:::: . :.: . :::: ::::: :: :::: ::. : : :
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
450 460 470 480 490 500
410 420 430 440 450 460
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
. :: . :. .: : :: : :: : : .::
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
510 520 530 540 550
470 480 490 500
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
560 570 580 590 600 610
>>XP_016857329 (OMIM: 606373,616193) PREDICTED: formin-2 (1102 aa)
initn: 376 init1: 376 opt: 498 Z-score: 184.7 bits: 44.8 E(85289): 0.0015
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:356-553)
250 260 270 280 290 300
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
::::: .: ::::: : . ::::: :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
330 340 350 360 370 380
310 320 330 340 350
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
: ::::: : :. ::::: :....::::: . ::::: ::... : ::
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
390 400 410 420 430 440
360 370 380 390 400
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
:::: . :.: . :::: ::::: :: :::: ::. : : :
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
450 460 470 480 490 500
410 420 430 440 450 460
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
. :: . :. .: : :: : :: : : .::
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
510 520 530 540 550
470 480 490 500
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
560 570 580 590 600 610
>>XP_016857328 (OMIM: 606373,616193) PREDICTED: formin-2 (1159 aa)
initn: 376 init1: 376 opt: 498 Z-score: 184.4 bits: 44.9 E(85289): 0.0016
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:413-610)
250 260 270 280 290 300
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
::::: .: ::::: : . ::::: :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
390 400 410 420 430 440
310 320 330 340 350
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
: ::::: : :. ::::: :....::::: . ::::: ::... : ::
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
450 460 470 480 490
360 370 380 390 400
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
:::: . :.: . :::: ::::: :: :::: ::. : : :
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
500 510 520 530 540 550
410 420 430 440 450 460
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
. :: . :. .: : :: : :: : : .::
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
560 570 580 590 600 610
470 480 490 500
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
620 630 640 650 660 670
>>XP_011542539 (OMIM: 606373,616193) PREDICTED: formin-2 (1360 aa)
initn: 376 init1: 376 opt: 498 Z-score: 183.6 bits: 44.9 E(85289): 0.0017
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:980-1177)
250 260 270 280 290 300
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
::::: .: ::::: : . ::::: :
XP_011 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
950 960 970 980 990 1000
310 320 330 340 350
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
: ::::: : :. ::::: :....::::: . ::::: ::... : ::
XP_011 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
1010 1020 1030 1040 1050 1060
360 370 380 390 400
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
:::: . :.: . :::: ::::: :: :::: ::. : : :
XP_011 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
1070 1080 1090 1100 1110 1120
410 420 430 440 450 460
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
. :: . :. .: : :: : :: : : .::
XP_011 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
1130 1140 1150 1160 1170
470 480 490 500
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED
XP_011 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
1180 1190 1200 1210 1220 1230
>>XP_016857327 (OMIM: 606373,616193) PREDICTED: formin-2 (1384 aa)
initn: 376 init1: 376 opt: 498 Z-score: 183.6 bits: 45.0 E(85289): 0.0017
Smith-Waterman score: 508; 41.8% identity (51.4% similar) in 208 aa overlap (277-467:980-1177)
250 260 270 280 290 300
pF1KB9 KDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARG
::::: .: ::::: : . ::::: :
XP_016 PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG
950 960 970 980 990 1000
310 320 330 340 350
pF1KB9 RGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPP--NRMYPPPPPALPSSA-PSGPP----
: ::::: : :. ::::: :....::::: . ::::: ::... : ::
XP_016 AGIPPPPP--LPGAGIPPPPPL-PGAGIPPPPPLPGAGIPPPPP-LPGAGIPPPPPLPGA
1010 1020 1030 1040 1050 1060
360 370 380 390 400
pF1KB9 --PPPPSVLGVGPVAPPPP------PPPPPPPGP--PPPPGLPSDGDHQVPTTAGNKAAL
:::: . :.: . :::: ::::: :: :::: ::. : : :
XP_016 GIPPPPPLPGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP
1070 1080 1090 1100 1110 1120
410 420 430 440 450 460
pF1KB9 LDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAPTSGIVG
. :: . :. .: : :: : :: : : .::
XP_016 PPPL-PGAGIPP----PPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP
1130 1140 1150 1160 1170
470 480 490 500
pF1KB9 ALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED
XP_016 PPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPP
1180 1190 1200 1210 1220 1230
505 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:40:12 2016 done: Sat Nov 5 19:40:14 2016
Total Scan time: 12.720 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]