FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9128, 902 aa 1>>>pF1KB9128 902 - 902 aa - 902 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9437+/-0.000556; mu= 12.7816+/- 0.034 mean_var=137.9478+/-27.843, 0's: 0 Z-trim(110.2): 350 B-trim: 301 in 1/54 Lambda= 0.109199 statistics sampled from 18066 (18479) to 18066 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.553), E-opt: 0.2 (0.217), width: 16 Scan time: 12.840 The best scores are: opt bits E(85289) NP_001165350 (OMIM: 311030) proto-oncogene DBL iso ( 941) 5584 892.9 0 XP_011529641 (OMIM: 311030) PREDICTED: proto-oncog (1001) 5584 893.0 0 XP_016885020 (OMIM: 311030) PREDICTED: proto-oncog (1001) 5584 893.0 0 NP_001165347 (OMIM: 311030) proto-oncogene DBL iso (1001) 5584 893.0 0 XP_005262470 (OMIM: 311030) PREDICTED: proto-oncog (1044) 5584 893.0 0 XP_016885021 (OMIM: 311030) PREDICTED: proto-oncog ( 938) 5521 883.0 0 XP_016885018 (OMIM: 311030) PREDICTED: proto-oncog (1041) 5521 883.0 0 XP_016885019 (OMIM: 311030) PREDICTED: proto-oncog ( 979) 5045 808.0 0 NP_005360 (OMIM: 311030) proto-oncogene DBL isofor ( 925) 3155 510.3 1.8e-143 NP_001093325 (OMIM: 311030) proto-oncogene DBL iso ( 985) 3155 510.3 1.9e-143 NP_001165348 (OMIM: 311030) proto-oncogene DBL iso ( 821) 2715 440.9 1.2e-122 NP_001165349 (OMIM: 311030) proto-oncogene DBL iso ( 860) 2616 425.3 6.1e-118 XP_016875987 (OMIM: 609499) PREDICTED: guanine nuc (1087) 1513 251.6 1.5e-65 XP_016875986 (OMIM: 609499) PREDICTED: guanine nuc (1096) 1513 251.6 1.5e-65 NP_079255 (OMIM: 609499) guanine nucleotide exchan (1123) 1513 251.7 1.5e-65 NP_001106203 (OMIM: 609499) guanine nucleotide exc (1125) 1513 251.7 1.5e-65 NP_001307745 (OMIM: 609499) guanine nucleotide exc (1129) 1513 251.7 1.5e-65 XP_016875984 (OMIM: 609499) PREDICTED: guanine nuc (1182) 1513 251.7 1.6e-65 XP_011535793 (OMIM: 609499) PREDICTED: guanine nuc (1143) 1474 245.5 1.1e-63 XP_011535792 (OMIM: 609499) PREDICTED: guanine nuc (1152) 1474 245.5 1.1e-63 XP_011535790 (OMIM: 609499) PREDICTED: guanine nuc (1163) 1474 245.5 1.1e-63 XP_011535789 (OMIM: 609499) PREDICTED: guanine nuc (1179) 1474 245.5 1.1e-63 XP_011535787 (OMIM: 609499) PREDICTED: guanine nuc (1181) 1474 245.5 1.1e-63 XP_011535786 (OMIM: 609499) PREDICTED: guanine nuc (1185) 1474 245.5 1.1e-63 XP_016875983 (OMIM: 609499) PREDICTED: guanine nuc (1187) 1474 245.5 1.1e-63 XP_011535785 (OMIM: 609499) PREDICTED: guanine nuc (1211) 1474 245.5 1.1e-63 XP_011535784 (OMIM: 609499) PREDICTED: guanine nuc (1211) 1474 245.5 1.1e-63 XP_011535788 (OMIM: 609499) PREDICTED: guanine nuc (1238) 1474 245.5 1.2e-63 NP_001307746 (OMIM: 609499) guanine nucleotide exc ( 984) 1467 244.4 2.1e-63 XP_016875988 (OMIM: 609499) PREDICTED: guanine nuc (1043) 1467 244.4 2.2e-63 XP_016875985 (OMIM: 609499) PREDICTED: guanine nuc (1112) 1467 244.4 2.3e-63 NP_001307744 (OMIM: 609499) guanine nucleotide exc (1148) 1467 244.4 2.3e-63 XP_016875982 (OMIM: 609499) PREDICTED: guanine nuc (1207) 1467 244.4 2.4e-63 NP_891992 (OMIM: 610215) rho guanine nucleotide ex ( 580) 631 112.5 6.2e-24 NP_001104740 (OMIM: 610215) rho guanine nucleotide ( 619) 631 112.5 6.5e-24 XP_016865292 (OMIM: 601893,617061) PREDICTED: trip (2612) 609 109.5 2.1e-22 XP_016865291 (OMIM: 601893,617061) PREDICTED: trip (2880) 609 109.6 2.3e-22 XP_011512412 (OMIM: 601893,617061) PREDICTED: trip (3038) 609 109.6 2.4e-22 XP_011512411 (OMIM: 601893,617061) PREDICTED: trip (3048) 609 109.6 2.4e-22 XP_011512410 (OMIM: 601893,617061) PREDICTED: trip (3058) 609 109.6 2.4e-22 XP_011512409 (OMIM: 601893,617061) PREDICTED: trip (3076) 609 109.6 2.4e-22 XP_016865290 (OMIM: 601893,617061) PREDICTED: trip (3093) 609 109.6 2.4e-22 NP_009049 (OMIM: 601893,617061) triple functional (3097) 609 109.6 2.4e-22 NP_001309919 (OMIM: 604605,608901) kalirin isoform (1650) 576 104.2 5.6e-21 XP_016862923 (OMIM: 604605,608901) PREDICTED: kali (1652) 576 104.2 5.6e-21 NP_003938 (OMIM: 604605,608901) kalirin isoform 2 (1663) 576 104.2 5.6e-21 XP_006713878 (OMIM: 604605,608901) PREDICTED: kali (1665) 576 104.2 5.6e-21 NP_001309921 (OMIM: 604605,608901) kalirin isoform (1613) 574 103.8 6.8e-21 NP_001309920 (OMIM: 604605,608901) kalirin isoform (1641) 574 103.9 6.9e-21 XP_016862924 (OMIM: 604605,608901) PREDICTED: kali (1643) 574 103.9 6.9e-21 >>NP_001165350 (OMIM: 311030) proto-oncogene DBL isoform (941 aa) initn: 5583 init1: 5583 opt: 5584 Z-score: 4764.9 bits: 892.9 E(85289): 0 Smith-Waterman score: 5838; 95.8% identity (95.8% similar) in 934 aa overlap (8-902:8-941) 10 20 30 40 50 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLP--- :::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLPVVM 10 20 30 40 50 60 60 70 80 pF1KB9 ------------------------------------AIENFALTVKEMAQMLQSFGTELA :::::::::::::::::::::::: NP_001 LSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIENFALTVKEMAQMLQSFGTELA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB9 ETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHR 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 QISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB9 QAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRC 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB9 NELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQ 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB9 KALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAG 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB9 FRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGYSFFQACKLFSKGKKTWRQNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGYSFFQACKLFSKGKKTWRQNQS 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB9 NLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAE 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB9 MDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDD 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB9 FQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB9 LLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWI 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB9 GHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVG 730 740 750 760 770 780 750 760 770 780 790 800 pF1KB9 ITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQD 790 800 810 820 830 840 810 820 830 840 850 860 pF1KB9 QLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQ 850 860 870 880 890 900 870 880 890 900 pF1KB9 SAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMALLY ::::::::::::::::::::::::::::::::::::::::: NP_001 SAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMALLY 910 920 930 940 >>XP_011529641 (OMIM: 311030) PREDICTED: proto-oncogene (1001 aa) initn: 5583 init1: 5583 opt: 5584 Z-score: 4764.5 bits: 893.0 E(85289): 0 Smith-Waterman score: 5779; 95.1% identity (95.6% similar) in 932 aa overlap (10-902:70-1001) 10 20 30 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRT :. ... .:::::::::::::::::::::: XP_011 TYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQRT 40 50 60 70 80 90 40 50 60 pF1KB9 FTDIGFWFSQEDFMLKLP---------------------------------------AIE :::::::::::::::::: ::: XP_011 FTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIE 100 110 120 130 140 150 70 80 90 100 110 120 pF1KB9 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL 160 170 180 190 200 210 130 140 150 160 170 180 pF1KB9 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ 220 230 240 250 260 270 190 200 210 220 230 240 pF1KB9 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI 280 290 300 310 320 330 250 260 270 280 290 300 pF1KB9 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD 340 350 360 370 380 390 310 320 330 340 350 360 pF1KB9 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ 400 410 420 430 440 450 370 380 390 400 410 420 pF1KB9 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY 460 470 480 490 500 510 430 440 450 460 470 480 pF1KB9 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL 520 530 540 550 560 570 490 500 510 520 530 540 pF1KB9 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS 580 590 600 610 620 630 550 560 570 580 590 600 pF1KB9 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR 640 650 660 670 680 690 610 620 630 640 650 660 pF1KB9 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING 700 710 720 730 740 750 670 680 690 700 710 720 pF1KB9 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG 760 770 780 790 800 810 730 740 750 760 770 780 pF1KB9 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE 820 830 840 850 860 870 790 800 810 820 830 840 pF1KB9 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE 880 890 900 910 920 930 850 860 870 880 890 900 pF1KB9 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL 940 950 960 970 980 990 pF1KB9 LY :: XP_011 LY 1000 >>XP_016885020 (OMIM: 311030) PREDICTED: proto-oncogene (1001 aa) initn: 5583 init1: 5583 opt: 5584 Z-score: 4764.5 bits: 893.0 E(85289): 0 Smith-Waterman score: 5779; 95.1% identity (95.6% similar) in 932 aa overlap (10-902:70-1001) 10 20 30 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRT :. ... .:::::::::::::::::::::: XP_016 TYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQRT 40 50 60 70 80 90 40 50 60 pF1KB9 FTDIGFWFSQEDFMLKLP---------------------------------------AIE :::::::::::::::::: ::: XP_016 FTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIE 100 110 120 130 140 150 70 80 90 100 110 120 pF1KB9 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL 160 170 180 190 200 210 130 140 150 160 170 180 pF1KB9 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ 220 230 240 250 260 270 190 200 210 220 230 240 pF1KB9 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI 280 290 300 310 320 330 250 260 270 280 290 300 pF1KB9 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD 340 350 360 370 380 390 310 320 330 340 350 360 pF1KB9 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ 400 410 420 430 440 450 370 380 390 400 410 420 pF1KB9 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY 460 470 480 490 500 510 430 440 450 460 470 480 pF1KB9 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL 520 530 540 550 560 570 490 500 510 520 530 540 pF1KB9 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS 580 590 600 610 620 630 550 560 570 580 590 600 pF1KB9 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR 640 650 660 670 680 690 610 620 630 640 650 660 pF1KB9 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING 700 710 720 730 740 750 670 680 690 700 710 720 pF1KB9 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG 760 770 780 790 800 810 730 740 750 760 770 780 pF1KB9 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE 820 830 840 850 860 870 790 800 810 820 830 840 pF1KB9 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE 880 890 900 910 920 930 850 860 870 880 890 900 pF1KB9 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL 940 950 960 970 980 990 pF1KB9 LY :: XP_016 LY 1000 >>NP_001165347 (OMIM: 311030) proto-oncogene DBL isoform (1001 aa) initn: 5583 init1: 5583 opt: 5584 Z-score: 4764.5 bits: 893.0 E(85289): 0 Smith-Waterman score: 5779; 95.1% identity (95.6% similar) in 932 aa overlap (10-902:70-1001) 10 20 30 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRT :. ... .:::::::::::::::::::::: NP_001 TYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQRT 40 50 60 70 80 90 40 50 60 pF1KB9 FTDIGFWFSQEDFMLKLP---------------------------------------AIE :::::::::::::::::: ::: NP_001 FTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIE 100 110 120 130 140 150 70 80 90 100 110 120 pF1KB9 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL 160 170 180 190 200 210 130 140 150 160 170 180 pF1KB9 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ 220 230 240 250 260 270 190 200 210 220 230 240 pF1KB9 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI 280 290 300 310 320 330 250 260 270 280 290 300 pF1KB9 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD 340 350 360 370 380 390 310 320 330 340 350 360 pF1KB9 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ 400 410 420 430 440 450 370 380 390 400 410 420 pF1KB9 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY 460 470 480 490 500 510 430 440 450 460 470 480 pF1KB9 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL 520 530 540 550 560 570 490 500 510 520 530 540 pF1KB9 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS 580 590 600 610 620 630 550 560 570 580 590 600 pF1KB9 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR 640 650 660 670 680 690 610 620 630 640 650 660 pF1KB9 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING 700 710 720 730 740 750 670 680 690 700 710 720 pF1KB9 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG 760 770 780 790 800 810 730 740 750 760 770 780 pF1KB9 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE 820 830 840 850 860 870 790 800 810 820 830 840 pF1KB9 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE 880 890 900 910 920 930 850 860 870 880 890 900 pF1KB9 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL 940 950 960 970 980 990 pF1KB9 LY :: NP_001 LY 1000 >>XP_005262470 (OMIM: 311030) PREDICTED: proto-oncogene (1044 aa) initn: 5583 init1: 5583 opt: 5584 Z-score: 4764.3 bits: 893.0 E(85289): 0 Smith-Waterman score: 5779; 95.1% identity (95.6% similar) in 932 aa overlap (10-902:113-1044) 10 20 30 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRT :. ... .:::::::::::::::::::::: XP_005 TYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQRT 90 100 110 120 130 140 40 50 60 pF1KB9 FTDIGFWFSQEDFMLKLP---------------------------------------AIE :::::::::::::::::: ::: XP_005 FTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIE 150 160 170 180 190 200 70 80 90 100 110 120 pF1KB9 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL 210 220 230 240 250 260 130 140 150 160 170 180 pF1KB9 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ 270 280 290 300 310 320 190 200 210 220 230 240 pF1KB9 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI 330 340 350 360 370 380 250 260 270 280 290 300 pF1KB9 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD 390 400 410 420 430 440 310 320 330 340 350 360 pF1KB9 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ 450 460 470 480 490 500 370 380 390 400 410 420 pF1KB9 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY 510 520 530 540 550 560 430 440 450 460 470 480 pF1KB9 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL 570 580 590 600 610 620 490 500 510 520 530 540 pF1KB9 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS 630 640 650 660 670 680 550 560 570 580 590 600 pF1KB9 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR 690 700 710 720 730 740 610 620 630 640 650 660 pF1KB9 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING 750 760 770 780 790 800 670 680 690 700 710 720 pF1KB9 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG 810 820 830 840 850 860 730 740 750 760 770 780 pF1KB9 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE 870 880 890 900 910 920 790 800 810 820 830 840 pF1KB9 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE 930 940 950 960 970 980 850 860 870 880 890 900 pF1KB9 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL 990 1000 1010 1020 1030 1040 pF1KB9 LY :: XP_005 LY >>XP_016885021 (OMIM: 311030) PREDICTED: proto-oncogene (938 aa) initn: 5520 init1: 5520 opt: 5521 Z-score: 4711.3 bits: 883.0 E(85289): 0 Smith-Waterman score: 5775; 95.8% identity (95.8% similar) in 924 aa overlap (8-892:8-931) 10 20 30 40 50 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLP--- :::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLPVVM 10 20 30 40 50 60 60 70 80 pF1KB9 ------------------------------------AIENFALTVKEMAQMLQSFGTELA :::::::::::::::::::::::: XP_016 LSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIENFALTVKEMAQMLQSFGTELA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB9 ETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHR 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 QISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB9 QAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRC 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB9 NELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQ 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB9 KALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAG 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB9 FRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGYSFFQACKLFSKGKKTWRQNQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGYSFFQACKLFSKGKKTWRQNQS 430 440 450 460 470 480 450 460 470 480 490 500 pF1KB9 NLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAE 490 500 510 520 530 540 510 520 530 540 550 560 pF1KB9 MDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDD 550 560 570 580 590 600 570 580 590 600 610 620 pF1KB9 FQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKE 610 620 630 640 650 660 630 640 650 660 670 680 pF1KB9 LLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWI 670 680 690 700 710 720 690 700 710 720 730 740 pF1KB9 GHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVG 730 740 750 760 770 780 750 760 770 780 790 800 pF1KB9 ITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQD 790 800 810 820 830 840 810 820 830 840 850 860 pF1KB9 QLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQ 850 860 870 880 890 900 870 880 890 900 pF1KB9 SAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMALLY ::::::::::::::::::::::::::::::: XP_016 SAEISEEPAEWSSNYFYPTYDENEEENRPLMLWYQKIK 910 920 930 >>XP_016885018 (OMIM: 311030) PREDICTED: proto-oncogene (1041 aa) initn: 5520 init1: 5520 opt: 5521 Z-score: 4710.6 bits: 883.0 E(85289): 0 Smith-Waterman score: 5716; 95.0% identity (95.6% similar) in 922 aa overlap (10-892:113-1034) 10 20 30 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRT :. ... .:::::::::::::::::::::: XP_016 TYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQRT 90 100 110 120 130 140 40 50 60 pF1KB9 FTDIGFWFSQEDFMLKLP---------------------------------------AIE :::::::::::::::::: ::: XP_016 FTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIE 150 160 170 180 190 200 70 80 90 100 110 120 pF1KB9 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL 210 220 230 240 250 260 130 140 150 160 170 180 pF1KB9 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ 270 280 290 300 310 320 190 200 210 220 230 240 pF1KB9 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI 330 340 350 360 370 380 250 260 270 280 290 300 pF1KB9 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD 390 400 410 420 430 440 310 320 330 340 350 360 pF1KB9 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ 450 460 470 480 490 500 370 380 390 400 410 420 pF1KB9 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY 510 520 530 540 550 560 430 440 450 460 470 480 pF1KB9 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL 570 580 590 600 610 620 490 500 510 520 530 540 pF1KB9 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS 630 640 650 660 670 680 550 560 570 580 590 600 pF1KB9 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR 690 700 710 720 730 740 610 620 630 640 650 660 pF1KB9 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING 750 760 770 780 790 800 670 680 690 700 710 720 pF1KB9 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG 810 820 830 840 850 860 730 740 750 760 770 780 pF1KB9 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE 870 880 890 900 910 920 790 800 810 820 830 840 pF1KB9 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE 930 940 950 960 970 980 850 860 870 880 890 900 pF1KB9 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL :::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMLWYQKIK 990 1000 1010 1020 1030 1040 pF1KB9 LY >>XP_016885019 (OMIM: 311030) PREDICTED: proto-oncogene (979 aa) initn: 5044 init1: 5044 opt: 5045 Z-score: 4305.7 bits: 808.0 E(85289): 0 Smith-Waterman score: 5240; 94.6% identity (95.2% similar) in 848 aa overlap (10-818:113-960) 10 20 30 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRT :. ... .:::::::::::::::::::::: XP_016 TYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQRT 90 100 110 120 130 140 40 50 60 pF1KB9 FTDIGFWFSQEDFMLKLP---------------------------------------AIE :::::::::::::::::: ::: XP_016 FTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIE 150 160 170 180 190 200 70 80 90 100 110 120 pF1KB9 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL 210 220 230 240 250 260 130 140 150 160 170 180 pF1KB9 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ 270 280 290 300 310 320 190 200 210 220 230 240 pF1KB9 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI 330 340 350 360 370 380 250 260 270 280 290 300 pF1KB9 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD 390 400 410 420 430 440 310 320 330 340 350 360 pF1KB9 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ 450 460 470 480 490 500 370 380 390 400 410 420 pF1KB9 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY 510 520 530 540 550 560 430 440 450 460 470 480 pF1KB9 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL 570 580 590 600 610 620 490 500 510 520 530 540 pF1KB9 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS 630 640 650 660 670 680 550 560 570 580 590 600 pF1KB9 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR 690 700 710 720 730 740 610 620 630 640 650 660 pF1KB9 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING 750 760 770 780 790 800 670 680 690 700 710 720 pF1KB9 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG 810 820 830 840 850 860 730 740 750 760 770 780 pF1KB9 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE 870 880 890 900 910 920 790 800 810 820 830 840 pF1KB9 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE :::::::::::::::::::::::::::::::::::::: XP_016 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEDLCRRWLSYIDEATMSNGK 930 940 950 960 970 850 860 870 880 890 900 pF1KB9 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL >>NP_005360 (OMIM: 311030) proto-oncogene DBL isoform b (925 aa) initn: 3530 init1: 3150 opt: 3155 Z-score: 2696.9 bits: 510.3 E(85289): 1.8e-143 Smith-Waterman score: 5733; 94.2% identity (94.2% similar) in 941 aa overlap (1-902:1-925) 10 20 30 40 50 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLP--- ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRTFTDIGFWFSQEDFMLKLPVVM 10 20 30 40 50 60 60 70 80 pF1KB9 ------------------------------------AIENFALTVKEMAQMLQSFGTELA :::::::::::::::::::::::: NP_005 LSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIENFALTVKEMAQMLQSFGTELA 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB9 ETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKILLTNLEVPDTEGAVSSRLECHR 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 QISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQLWKFEQDFQQLVTEVEFLLNQ 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB9 QAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVILHGHKLAANHHYALDLICQRC 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB9 NELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCDEGECLLANQEIDKFQSKEDAQ 310 320 330 340 350 360 330 340 350 360 370 380 pF1KB9 KALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 KALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQMKTIQLKLENIRSIFENQQAG 370 380 390 400 410 420 390 400 410 420 430 440 pF1KB9 FRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGYSFFQACKLFSKGKKTWRQNQS :::::::::::::::::::::::::::::::::: :::::::::: NP_005 FRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQ----------------GKKTWRQNQS 430 440 450 460 450 460 470 480 490 500 pF1KB9 NLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 NLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAE 470 480 490 500 510 520 510 520 530 540 550 560 pF1KB9 MDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERVGPCFLERKDD 530 540 550 560 570 580 570 580 590 600 610 620 pF1KB9 FQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKE 590 600 610 620 630 640 630 640 650 660 670 680 pF1KB9 LLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 LLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAINGYIGNLNELGKMIMQGGFSVWI 650 660 670 680 690 700 690 700 710 720 730 740 pF1KB9 GHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 GHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESGEGSDRYPSYSFKHCWKMDEVG 710 720 730 740 750 760 750 760 770 780 790 800 pF1KB9 ITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 ITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKEIRNILLKQQELLTVKKRKQQD 770 780 790 800 810 820 810 820 830 840 850 860 pF1KB9 QLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVEVCEAIASVQAEANTVWTEASQ 830 840 850 860 870 880 870 880 890 900 pF1KB9 SAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMALLY ::::::::::::::::::::::::::::::::::::::::: NP_005 SAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMALLY 890 900 910 920 >>NP_001093325 (OMIM: 311030) proto-oncogene DBL isoform (985 aa) initn: 3424 init1: 3150 opt: 3155 Z-score: 2696.5 bits: 510.3 E(85289): 1.9e-143 Smith-Waterman score: 5627; 93.3% identity (93.9% similar) in 932 aa overlap (10-902:70-985) 10 20 30 pF1KB9 MAEANPRRGKMRFRRNAASFPGNLHLVLVLRPTSFLQRT :. ... .:::::::::::::::::::::: NP_001 TYLTSIARQNGSDSRFTIILDRRLDTWSSLKISLQKISASFPGNLHLVLVLRPTSFLQRT 40 50 60 70 80 90 40 50 60 pF1KB9 FTDIGFWFSQEDFMLKLP---------------------------------------AIE :::::::::::::::::: ::: NP_001 FTDIGFWFSQEDFMLKLPVVMLSSVSDLLTYIDDKQLTPELGGTLQYCHSEWIIFRNAIE 100 110 120 130 140 150 70 80 90 100 110 120 pF1KB9 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NFALTVKEMAQMLQSFGTELAETELPDDIPSIEEILAIRAERYHLLKNDITAVTKEGKIL 160 170 180 190 200 210 130 140 150 160 170 180 pF1KB9 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTNLEVPDTEGAVSSRLECHRQISGDWQTINKLLTQVHDMETAFDGFWEKHQLKMEQYLQ 220 230 240 250 260 270 190 200 210 220 230 240 pF1KB9 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LWKFEQDFQQLVTEVEFLLNQQAELADVTGTIAQVKQKIKKLENLDENSQELLSKAQFVI 280 290 300 310 320 330 250 260 270 280 290 300 pF1KB9 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHGHKLAANHHYALDLICQRCNELRYLSDILVNEIKAKRIQLSRTFKMHKLLQQARQCCD 340 350 360 370 380 390 310 320 330 340 350 360 pF1KB9 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGECLLANQEIDKFQSKEDAQKALQDIENFLEMALPFINYEPETLQYEFDVILSPELKVQ 400 410 420 430 440 450 370 380 390 400 410 420 pF1KB9 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQVGVGY ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTIQLKLENIRSIFENQQAGFRNLADKHVRPIQFVVPTPENLVTSGTPFFSSKQ----- 460 470 480 490 500 510 430 440 450 460 470 480 pF1KB9 SFFQACKLFSKGKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -----------GKKTWRQNQSNLKIEVVPDCQEKRSSGPSSSLDNGNSLDVLKNHVLNEL 520 530 540 550 560 490 500 510 520 530 540 pF1KB9 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKKDILFGNMAEIYEFHNDIFLSS 570 580 590 600 610 620 550 560 570 580 590 600 pF1KB9 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LENCAHAPERVGPCFLERKDDFQMYAKYCQNKPRSETIWRKYSECAFFQECQRKLKHRLR 630 640 650 660 670 680 610 620 630 640 650 660 pF1KB9 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LDSYLLKPVQRITKYQLLLKELLKYSKDCEGSALLKKALDAMLDLLKSVNDSMHQIAING 690 700 710 720 730 740 670 680 690 700 710 720 pF1KB9 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YIGNLNELGKMIMQGGFSVWIGHKKGATKMKDLARFKPMQRHLFLYEKAIVFCKRRVESG 750 760 770 780 790 800 730 740 750 760 770 780 pF1KB9 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EGSDRYPSYSFKHCWKMDEVGITEYVKGDNRKFEIWYGEKEEVYIVQASNVDVKMTWLKE 810 820 830 840 850 860 790 800 810 820 830 840 pF1KB9 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IRNILLKQQELLTVKKRKQQDQLTERDKFQISLQQNDEKQQGAFISTEETELEHTSTVVE 870 880 890 900 910 920 850 860 870 880 890 900 pF1KB9 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VCEAIASVQAEANTVWTEASQSAEISEEPAEWSSNYFYPTYDENEEENRPLMRPVSEMAL 930 940 950 960 970 980 pF1KB9 LY :: NP_001 LY 902 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:03:04 2016 done: Thu Nov 3 23:03:06 2016 Total Scan time: 12.840 Total Display time: 0.350 Function used was FASTA [36.3.4 Apr, 2011]