FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9131, 579 aa
1>>>pF1KB9131 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7271+/-0.00036; mu= 13.5354+/- 0.023
mean_var=107.1560+/-21.191, 0's: 0 Z-trim(116.2): 406 B-trim: 0 in 0/58
Lambda= 0.123898
statistics sampled from 26826 (27240) to 26826 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.319), width: 16
Scan time: 10.990
The best scores are: opt bits E(85289)
NP_005117 (OMIM: 602304) nuclear receptor subfamil ( 579) 3895 707.0 4.3e-203
NP_001138897 (OMIM: 602304) nuclear receptor subfa ( 504) 3413 620.8 3.3e-177
XP_006713514 (OMIM: 602304) PREDICTED: nuclear rec ( 448) 3066 558.7 1.4e-158
NP_068370 (OMIM: 602408) nuclear receptor subfamil ( 614) 1722 318.6 3.8e-86
XP_011520181 (OMIM: 600825) PREDICTED: nuclear rec ( 376) 477 95.9 2.5e-19
XP_016877956 (OMIM: 600825) PREDICTED: nuclear rec ( 386) 477 95.9 2.5e-19
XP_011520180 (OMIM: 600825) PREDICTED: nuclear rec ( 386) 477 95.9 2.5e-19
NP_803184 (OMIM: 600409) peroxisome proliferator-a ( 361) 462 93.2 1.5e-18
XP_016866464 (OMIM: 600409) PREDICTED: peroxisome ( 365) 462 93.2 1.5e-18
XP_011532146 (OMIM: 125853,601487,601665,604367,60 ( 250) 457 92.3 2.1e-18
NP_001317544 (OMIM: 125853,601487,601665,604367,60 ( 250) 457 92.3 2.1e-18
XP_011532145 (OMIM: 125853,601487,601665,604367,60 ( 278) 457 92.3 2.3e-18
XP_011532144 (OMIM: 125853,601487,601665,604367,60 ( 445) 457 92.4 3.4e-18
NP_599023 (OMIM: 600825) nuclear receptor ROR-alph ( 523) 448 90.8 1.2e-17
XP_006724333 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
NP_005027 (OMIM: 170998) peroxisome proliferator-a ( 468) 447 90.6 1.2e-17
XP_011528544 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
XP_006724332 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
XP_011528545 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
XP_005261713 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
XP_011528543 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
NP_001001928 (OMIM: 170998) peroxisome proliferato ( 468) 447 90.6 1.2e-17
XP_005261712 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
XP_011528542 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
XP_011528541 (OMIM: 170998) PREDICTED: peroxisome ( 468) 447 90.6 1.2e-17
XP_011518110 (OMIM: 602423) PREDICTED: oxysterols ( 235) 436 88.5 2.7e-17
XP_011518109 (OMIM: 602423) PREDICTED: oxysterols ( 313) 436 88.6 3.4e-17
XP_005252773 (OMIM: 602423) PREDICTED: oxysterols ( 313) 436 88.6 3.4e-17
XP_005252772 (OMIM: 602423) PREDICTED: oxysterols ( 358) 436 88.6 3.8e-17
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols ( 402) 436 88.6 4.2e-17
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402) 436 88.6 4.2e-17
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols ( 402) 436 88.6 4.2e-17
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols ( 402) 436 88.6 4.2e-17
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols ( 402) 436 88.6 4.2e-17
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols ( 402) 436 88.6 4.2e-17
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447) 436 88.6 4.6e-17
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols ( 447) 436 88.6 4.6e-17
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols ( 447) 436 88.6 4.6e-17
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols ( 447) 436 88.6 4.6e-17
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols ( 447) 436 88.6 4.6e-17
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols ( 447) 436 88.6 4.6e-17
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols ( 447) 436 88.6 4.6e-17
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453) 436 88.6 4.6e-17
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453) 436 88.6 4.6e-17
XP_005254641 (OMIM: 600825) PREDICTED: nuclear rec ( 477) 433 88.1 7e-17
XP_011520177 (OMIM: 600825) PREDICTED: nuclear rec ( 504) 433 88.1 7.3e-17
XP_016877955 (OMIM: 600825) PREDICTED: nuclear rec ( 460) 428 87.2 1.3e-16
XP_011520179 (OMIM: 600825) PREDICTED: nuclear rec ( 467) 428 87.2 1.3e-16
NP_599024 (OMIM: 600825) nuclear receptor ROR-alph ( 468) 428 87.2 1.3e-16
XP_011520176 (OMIM: 600825) PREDICTED: nuclear rec ( 525) 428 87.2 1.4e-16
>>NP_005117 (OMIM: 602304) nuclear receptor subfamily 1 (579 aa)
initn: 3895 init1: 3895 opt: 3895 Z-score: 3767.2 bits: 707.0 E(85289): 4.3e-203
Smith-Waterman score: 3895; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)
10 20 30 40 50 60
pF1KB9 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLI
490 500 510 520 530 540
550 560 570
pF1KB9 MKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
:::::::::::::::::::::::::::::::::::::::
NP_005 MKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
550 560 570
>>NP_001138897 (OMIM: 602304) nuclear receptor subfamily (504 aa)
initn: 3413 init1: 3413 opt: 3413 Z-score: 3302.5 bits: 620.8 E(85289): 3.3e-177
Smith-Waterman score: 3413; 100.0% identity (100.0% similar) in 504 aa overlap (76-579:1-504)
50 60 70 80 90 100
pF1KB9 SSNSDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKV
::::::::::::::::::::::::::::::
NP_001 MKTSKSSAPGMTKSHSGVTKFSGMVLLCKV
10 20 30
110 120 130 140 150 160
pF1KB9 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCL
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB9 SVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQE
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB9 QLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB9 RIPKNMEQYNLNHDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPKNMEQYNLNHDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMN
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB9 FSNAYTQRVCDRVPIDGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAYTQRVCDRVPIDGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEF
280 290 300 310 320 330
410 420 430 440 450 460
pF1KB9 SMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLS
340 350 360 370 380 390
470 480 490 500 510 520
pF1KB9 GKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSV
400 410 420 430 440 450
530 540 550 560 570
pF1KB9 EALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
460 470 480 490 500
>>XP_006713514 (OMIM: 602304) PREDICTED: nuclear recepto (448 aa)
initn: 3188 init1: 3066 opt: 3066 Z-score: 2968.0 bits: 558.7 E(85289): 1.4e-158
Smith-Waterman score: 3066; 99.8% identity (100.0% similar) in 445 aa overlap (1-445:1-445)
10 20 30 40 50 60
pF1KB9 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
::::::::::::::::::::::::.
XP_006 KRIPGFRDLSQHDQVNLLKAGTFEIDLE
430 440
>>NP_068370 (OMIM: 602408) nuclear receptor subfamily 1 (614 aa)
initn: 1836 init1: 910 opt: 1722 Z-score: 1667.6 bits: 318.6 E(85289): 3.8e-86
Smith-Waterman score: 1783; 51.1% identity (72.5% similar) in 614 aa overlap (4-577:9-611)
10 20 30 40 50
pF1KB9 MEVNAGGVIAYISSSSSA---SSPASCHSEGSENSFQSSSSSVPSS-PNSSNSDT
:.::::.::.::.:. .:: : .:..:..:::: ... :. : : ...
NP_068 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL
10 20 30 40 50 60
60 70 80 90
pF1KB9 NGNPKNGDLANIEGILKNDRIDCSMKTSKSSA--------PGM-------------TKSH
. .: . ...: :..: : ..:.::. :: .::
NP_068 TQDPARS-FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKST
70 80 90 100 110
100 110 120 130 140 150
pF1KB9 SGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMR
:..::..:::::::::::::::::::::::::::::::::::::::::.:::::::::.:
NP_068 SNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVR
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB9 MNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQND
.::::::::::::::::::::::::::::::::::::: ::::::. . :.:.:.. .
NP_068 INRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-LANNQLSSQCPLE
180 190 200 210 220 230
220 230 240 250 260
pF1KB9 TLVEHHEQTALPAQEQLRPKP---------QLEQENIKSSSPPSSDFAKEEVIGMVTRAH
: .: : : . : : :. :. . :: . . :.::..:.:::
NP_068 TSPTQHP-TPGPMGPSPPPAPVPSPLVGFSQFPQQ-LTPPRSPSPEPTVEDVISQVARAH
240 250 260 270 280 290
270 280 290 300 310
pF1KB9 KDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDHCGNGLSSHFPCSESQQH---L
.. : : ... .: ... ... : . ... : . ... . .:.: :
NP_068 REIFTYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLA-AQRHNEAL
300 310 320 330 340 350
320 330 340 350 360 370
pF1KB9 NGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENK---NSYLCN
:: .. . :: :. : . ::. .:.: : .. :.: :: .
NP_068 NGLRQAPS--SYPPTWPPGPAHHSCHQ-SNSNGHRLC---PTHVYAAPEGKAPANSPRQG
360 370 380 390 400
380 390 400 410 420 430
pF1KB9 TGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQV
.. . :.:::. :. .. .::::.:::::::::.:::::::.:::::::::::::
NP_068 NSKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQV
410 420 430 440 450 460
440 450 460 470 480 490
pF1KB9 NLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNA
.::::::::::::::::::..:..:: ::: ::...: .:: ::::..::.::::::.
NP_068 TLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNS
470 480 490 500 510 520
500 510 520 530 540 550
pF1KB9 LQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLL
: :..::..::::::::::::::.:: ::: :::::.::::.:..::.: :.: :::::
NP_068 LALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLL
530 540 550 560 570 580
560 570
pF1KB9 LKLPDLRSLNNMHSEELLAFKVHP
:::::::.:::::::.::.:.:
NP_068 LKLPDLRTLNNMHSEKLLSFRVDAQ
590 600 610
>>XP_011520181 (OMIM: 600825) PREDICTED: nuclear recepto (376 aa)
initn: 339 init1: 204 opt: 477 Z-score: 468.1 bits: 95.9 E(85289): 2.5e-19
Smith-Waterman score: 494; 32.5% identity (65.7% similar) in 335 aa overlap (271-579:19-349)
250 260 270 280 290
pF1KB9 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERI-PK-NMEQYNLN-
::.. ...:: ..: . : :. .:.
XP_011 MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTE
10 20 30 40
300 310 320 330 340
pF1KB9 -HDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYP-------NG---HAIC---IANG--
:: .: ...: : . . . ..: .:. : :: . :: :.:
XP_011 LHDDLSNYIDGHTPEGSKADSAVSSFY-LDIQPSPDQSGLDINGIKPEPICDYTPASGFF
50 60 70 80 90 100
350 360 370 380 390
pF1KB9 -HCMNFSNAYTQRVCDRVPIDGFSQNENKN-----SYLCNTGGRMHLVCPMSKSPYVDPH
.: .:.:. :. . . . .. ..:: .:. .:: . .. ... .
XP_011 PYC-SFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQN
110 120 130 140 150 160
400 410 420 430 440 450
pF1KB9 KSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFD
:. . .:. ....: :.. :::::::: :: .: :.::. :::::..::...:. ::
XP_011 KQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFD
170 180 190 200 210 220
460 470 480 490 500 510
pF1KB9 AKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSAD
... :: : .:: : : ..:.: :... .:::...: ...:...:..::.: ::.:::
XP_011 SQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSAD
230 240 250 260 270 280
520 530 540 550 560 570
pF1KB9 RSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAF
:: ... ..: ::. . ::. ...::: : .:.:::. :. ::.: . :.:.:.::
XP_011 RSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAF
290 300 310 320 330 340
pF1KB9 K-VHP
: ..:
XP_011 KAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
350 360 370
>>XP_016877956 (OMIM: 600825) PREDICTED: nuclear recepto (386 aa)
initn: 388 init1: 204 opt: 477 Z-score: 467.9 bits: 95.9 E(85289): 2.5e-19
Smith-Waterman score: 500; 31.4% identity (64.1% similar) in 357 aa overlap (255-579:9-359)
230 240 250 260 270 280
pF1KB9 EQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQ---ENSAESMQP
: ... ..:. .: . :. ... .. :
XP_016 MSRDAVKFGRMSKKQRDS-LYAEVQKHRMQQQQRDHQQ
10 20 30
290 300 310 320 330
pF1KB9 QRGERIPKNMEQYNLN-------HDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYP---
: :: : . ::.. :: .: ...: : . . . ..: .:. :
XP_016 QPGEAEPLT-PTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFY-LDIQPSPDQS
40 50 60 70 80 90
340 350 360 370
pF1KB9 ----NG---HAIC---IANG---HCMNFSNAYTQRVCDRVPIDGFSQNENKN-----SYL
:: . :: :.: .: .:.:. :. . . . .. ..:: .:. .::
XP_016 GLDINGIKPEPICDYTPASGFFPYC-SFTNGETSPTVSMAELEHLAQNISKSHLETCQYL
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB9 CNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHD
. .. ... .:. . .:. ....: :.. :::::::: :: .: :.:
XP_016 REELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQND
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB9 QVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKL
:. :::::..::...:. ::... :: : .:: : : ..:.: :... .:::...:
XP_016 QIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSL
220 230 240 250 260 270
500 510 520 530 540 550
pF1KB9 NALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTK
...:...:..::.: ::.::::: ... ..: ::. . ::. ...::: : .:.::
XP_016 CSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTK
280 290 300 310 320 330
560 570
pF1KB9 LLLKLPDLRSLNNMHSEELLAFK-VHP
:. :. ::.: . :.:.:.::: ..:
XP_016 LICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
340 350 360 370 380
>>XP_011520180 (OMIM: 600825) PREDICTED: nuclear recepto (386 aa)
initn: 388 init1: 204 opt: 477 Z-score: 467.9 bits: 95.9 E(85289): 2.5e-19
Smith-Waterman score: 500; 31.4% identity (64.1% similar) in 357 aa overlap (255-579:9-359)
230 240 250 260 270 280
pF1KB9 EQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQ---ENSAESMQP
: ... ..:. .: . :. ... .. :
XP_011 MSRDAVKFGRMSKKQRDS-LYAEVQKHRMQQQQRDHQQ
10 20 30
290 300 310 320 330
pF1KB9 QRGERIPKNMEQYNLN-------HDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYP---
: :: : . ::.. :: .: ...: : . . . ..: .:. :
XP_011 QPGEAEPLT-PTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFY-LDIQPSPDQS
40 50 60 70 80 90
340 350 360 370
pF1KB9 ----NG---HAIC---IANG---HCMNFSNAYTQRVCDRVPIDGFSQNENKN-----SYL
:: . :: :.: .: .:.:. :. . . . .. ..:: .:. .::
XP_011 GLDINGIKPEPICDYTPASGFFPYC-SFTNGETSPTVSMAELEHLAQNISKSHLETCQYL
100 110 120 130 140 150
380 390 400 410 420 430
pF1KB9 CNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHD
. .. ... .:. . .:. ....: :.. :::::::: :: .: :.:
XP_011 REELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQND
160 170 180 190 200 210
440 450 460 470 480 490
pF1KB9 QVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKL
:. :::::..::...:. ::... :: : .:: : : ..:.: :... .:::...:
XP_011 QIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSL
220 230 240 250 260 270
500 510 520 530 540 550
pF1KB9 NALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTK
...:...:..::.: ::.::::: ... ..: ::. . ::. ...::: : .:.::
XP_011 CSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTK
280 290 300 310 320 330
560 570
pF1KB9 LLLKLPDLRSLNNMHSEELLAFK-VHP
:. :. ::.: . :.:.:.::: ..:
XP_011 LICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
340 350 360 370 380
>>NP_803184 (OMIM: 600409) peroxisome proliferator-activ (361 aa)
initn: 589 init1: 228 opt: 462 Z-score: 453.9 bits: 93.2 E(85289): 1.5e-18
Smith-Waterman score: 462; 45.8% identity (73.6% similar) in 144 aa overlap (79-212:46-187)
50 60 70 80 90 100
pF1KB9 SDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPG--MTKSHSGVTKFS--GMVLLCK
:.::.: . . . : : .. . :.
NP_803 EKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECR
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB9 VCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKC
:::: ::::::::::::::::::::.:.....:.:: .. :.:.. :::.:: :::.::
NP_803 VCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERS--CKIQKKNRNKCQYCRFQKC
80 90 100 110 120 130
170 180 190 200 210
pF1KB9 LSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ------FSGHLQNDTLVEHHEQ
:..:::..:.::::.:. ::.... . . ...: : :: :. : :
NP_803 LALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMT
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB9 TALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAES
NP_803 KKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTT
200 210 220 230 240 250
>--
initn: 211 init1: 124 opt: 196 Z-score: 196.9 bits: 45.7 E(85289): 0.00031
Smith-Waterman score: 196; 34.1% identity (69.1% similar) in 123 aa overlap (394-512:237-357)
370 380 390 400 410 420
pF1KB9 SQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHK--SGHEIWEEFSMSFTPAVKEVVEFAK
:.: : : .. . . . . .:.:..::::
NP_803 HTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVH-VFYRCQCTTVETVRELTEFAK
210 220 230 240 250 260
430 440 450 460 470
pF1KB9 RIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGA--
::.: .: .:::.::: :. :.... .::. . :. :: . . :.:.
NP_803 SIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGF-VTREFLRSLRKPF
270 280 290 300 310 320
480 490 500 510 520 530
pF1KB9 GDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTL
.:... :::. :.:::.:.: ...:: :....
NP_803 SDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGGE
330 340 350 360
540 550 560 570
pF1KB9 IMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
>>XP_016866464 (OMIM: 600409) PREDICTED: peroxisome prol (365 aa)
initn: 589 init1: 228 opt: 462 Z-score: 453.8 bits: 93.2 E(85289): 1.5e-18
Smith-Waterman score: 462; 45.8% identity (73.6% similar) in 144 aa overlap (79-212:46-187)
50 60 70 80 90 100
pF1KB9 SDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPG--MTKSHSGVTKFS--GMVLLCK
:.::.: . . . : : .. . :.
XP_016 EKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECR
20 30 40 50 60 70
110 120 130 140 150 160
pF1KB9 VCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKC
:::: ::::::::::::::::::::.:.....:.:: .. :.:.. :::.:: :::.::
XP_016 VCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERS--CKIQKKNRNKCQYCRFQKC
80 90 100 110 120 130
170 180 190 200 210
pF1KB9 LSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ------FSGHLQNDTLVEHHEQ
:..:::..:.::::.:. ::.... . . ...: : :: :. : :
XP_016 LALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMT
140 150 160 170 180 190
220 230 240 250 260 270
pF1KB9 TALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAES
XP_016 KKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTT
200 210 220 230 240 250
>--
initn: 211 init1: 124 opt: 196 Z-score: 196.8 bits: 45.7 E(85289): 0.00032
Smith-Waterman score: 196; 34.1% identity (69.1% similar) in 123 aa overlap (394-512:237-357)
370 380 390 400 410 420
pF1KB9 SQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHK--SGHEIWEEFSMSFTPAVKEVVEFAK
:.: : : .. . . . . .:.:..::::
XP_016 HTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVH-VFYRCQCTTVETVRELTEFAK
210 220 230 240 250 260
430 440 450 460 470
pF1KB9 RIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGA--
::.: .: .:::.::: :. :.... .::. . :. :: . . :.:.
XP_016 SIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGF-VTREFLRSLRKPF
270 280 290 300 310 320
480 490 500 510 520 530
pF1KB9 GDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTL
.:... :::. :.:::.:.: ...:: :....
XP_016 SDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGAAAEDG
330 340 350 360
540 550 560 570
pF1KB9 IMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
>>XP_011532146 (OMIM: 125853,601487,601665,604367,609338 (250 aa)
initn: 456 init1: 238 opt: 457 Z-score: 451.4 bits: 92.3 E(85289): 2.1e-18
Smith-Waterman score: 457; 40.1% identity (68.7% similar) in 182 aa overlap (25-198:28-204)
10 20 30 40 50
pF1KB9 MEVNAGGVIAYISSSSSASSPASCHSEGSE-NSFQSSSSSVPSSPNSSNSD-TNGNP
::.. . . : . . : :.:. . : .:
XP_011 MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP
10 20 30 40 50 60
60 70 80 90 100
pF1KB9 KNGDLANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKF------SGMVLLCKVCGDV
.:. . :: .. . ..:. .: : .... . .: : :.. :.::::
XP_011 V---VADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDK
70 80 90 100 110
110 120 130 140 150 160
pF1KB9 ASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGM
::::::::::::::::::::.:. .. : .: . :: : . .::.:: :::.:::.:::
XP_011 ASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCRFQKCLAVGM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB9 SRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRP
:..:.::::.:. ::...: :..: . .
XP_011 SHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARA
180 190 200 210 220 230
579 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:03:45 2016 done: Thu Nov 3 23:03:46 2016
Total Scan time: 10.990 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]