Result of FASTA (omim) for pF1KB9131
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9131, 579 aa
  1>>>pF1KB9131 579 - 579 aa - 579 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.7271+/-0.00036; mu= 13.5354+/- 0.023
 mean_var=107.1560+/-21.191, 0's: 0 Z-trim(116.2): 406  B-trim: 0 in 0/58
 Lambda= 0.123898
 statistics sampled from 26826 (27240) to 26826 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.319), width:  16
 Scan time: 10.990

The best scores are:                                      opt bits E(85289)
NP_005117 (OMIM: 602304) nuclear receptor subfamil ( 579) 3895 707.0 4.3e-203
NP_001138897 (OMIM: 602304) nuclear receptor subfa ( 504) 3413 620.8 3.3e-177
XP_006713514 (OMIM: 602304) PREDICTED: nuclear rec ( 448) 3066 558.7 1.4e-158
NP_068370 (OMIM: 602408) nuclear receptor subfamil ( 614) 1722 318.6 3.8e-86
XP_011520181 (OMIM: 600825) PREDICTED: nuclear rec ( 376)  477 95.9 2.5e-19
XP_016877956 (OMIM: 600825) PREDICTED: nuclear rec ( 386)  477 95.9 2.5e-19
XP_011520180 (OMIM: 600825) PREDICTED: nuclear rec ( 386)  477 95.9 2.5e-19
NP_803184 (OMIM: 600409) peroxisome proliferator-a ( 361)  462 93.2 1.5e-18
XP_016866464 (OMIM: 600409) PREDICTED: peroxisome  ( 365)  462 93.2 1.5e-18
XP_011532146 (OMIM: 125853,601487,601665,604367,60 ( 250)  457 92.3 2.1e-18
NP_001317544 (OMIM: 125853,601487,601665,604367,60 ( 250)  457 92.3 2.1e-18
XP_011532145 (OMIM: 125853,601487,601665,604367,60 ( 278)  457 92.3 2.3e-18
XP_011532144 (OMIM: 125853,601487,601665,604367,60 ( 445)  457 92.4 3.4e-18
NP_599023 (OMIM: 600825) nuclear receptor ROR-alph ( 523)  448 90.8 1.2e-17
XP_006724333 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
NP_005027 (OMIM: 170998) peroxisome proliferator-a ( 468)  447 90.6 1.2e-17
XP_011528544 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
XP_006724332 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
XP_011528545 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
XP_005261713 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
XP_011528543 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
NP_001001928 (OMIM: 170998) peroxisome proliferato ( 468)  447 90.6 1.2e-17
XP_005261712 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
XP_011528542 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
XP_011528541 (OMIM: 170998) PREDICTED: peroxisome  ( 468)  447 90.6 1.2e-17
XP_011518110 (OMIM: 602423) PREDICTED: oxysterols  ( 235)  436 88.5 2.7e-17
XP_011518109 (OMIM: 602423) PREDICTED: oxysterols  ( 313)  436 88.6 3.4e-17
XP_005252773 (OMIM: 602423) PREDICTED: oxysterols  ( 313)  436 88.6 3.4e-17
XP_005252772 (OMIM: 602423) PREDICTED: oxysterols  ( 358)  436 88.6 3.8e-17
XP_006718179 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  436 88.6 4.2e-17
NP_001123574 (OMIM: 602423) oxysterols receptor LX ( 402)  436 88.6 4.2e-17
XP_005252767 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  436 88.6 4.2e-17
XP_006718178 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  436 88.6 4.2e-17
XP_016872547 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  436 88.6 4.2e-17
XP_005252766 (OMIM: 602423) PREDICTED: oxysterols  ( 402)  436 88.6 4.2e-17
NP_005684 (OMIM: 602423) oxysterols receptor LXR-a ( 447)  436 88.6 4.6e-17
XP_005252764 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  436 88.6 4.6e-17
XP_005252763 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  436 88.6 4.6e-17
XP_006718176 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  436 88.6 4.6e-17
XP_005252762 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  436 88.6 4.6e-17
XP_011518107 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  436 88.6 4.6e-17
XP_006718175 (OMIM: 602423) PREDICTED: oxysterols  ( 447)  436 88.6 4.6e-17
NP_001238863 (OMIM: 602423) oxysterols receptor LX ( 453)  436 88.6 4.6e-17
NP_001238864 (OMIM: 602423) oxysterols receptor LX ( 453)  436 88.6 4.6e-17
XP_005254641 (OMIM: 600825) PREDICTED: nuclear rec ( 477)  433 88.1   7e-17
XP_011520177 (OMIM: 600825) PREDICTED: nuclear rec ( 504)  433 88.1 7.3e-17
XP_016877955 (OMIM: 600825) PREDICTED: nuclear rec ( 460)  428 87.2 1.3e-16
XP_011520179 (OMIM: 600825) PREDICTED: nuclear rec ( 467)  428 87.2 1.3e-16
NP_599024 (OMIM: 600825) nuclear receptor ROR-alph ( 468)  428 87.2 1.3e-16
XP_011520176 (OMIM: 600825) PREDICTED: nuclear rec ( 525)  428 87.2 1.4e-16


>>NP_005117 (OMIM: 602304) nuclear receptor subfamily 1   (579 aa)
 initn: 3895 init1: 3895 opt: 3895  Z-score: 3767.2  bits: 707.0 E(85289): 4.3e-203
Smith-Waterman score: 3895; 100.0% identity (100.0% similar) in 579 aa overlap (1-579:1-579)

               10        20        30        40        50        60
pF1KB9 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB9 DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 DLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLI
              490       500       510       520       530       540

              550       560       570         
pF1KB9 MKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
       :::::::::::::::::::::::::::::::::::::::
NP_005 MKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
              550       560       570         

>>NP_001138897 (OMIM: 602304) nuclear receptor subfamily  (504 aa)
 initn: 3413 init1: 3413 opt: 3413  Z-score: 3302.5  bits: 620.8 E(85289): 3.3e-177
Smith-Waterman score: 3413; 100.0% identity (100.0% similar) in 504 aa overlap (76-579:1-504)

          50        60        70        80        90       100     
pF1KB9 SSNSDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKV
                                     ::::::::::::::::::::::::::::::
NP_001                               MKTSKSSAPGMTKSHSGVTKFSGMVLLCKV
                                             10        20        30

         110       120       130       140       150       160     
pF1KB9 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCL
               40        50        60        70        80        90

         170       180       190       200       210       220     
pF1KB9 SVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQE
              100       110       120       130       140       150

         230       240       250       260       270       280     
pF1KB9 QLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGE
              160       170       180       190       200       210

         290       300       310       320       330       340     
pF1KB9 RIPKNMEQYNLNHDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIPKNMEQYNLNHDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMN
              220       230       240       250       260       270

         350       360       370       380       390       400     
pF1KB9 FSNAYTQRVCDRVPIDGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSNAYTQRVCDRVPIDGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEF
              280       290       300       310       320       330

         410       420       430       440       450       460     
pF1KB9 SMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLS
              340       350       360       370       380       390

         470       480       490       500       510       520     
pF1KB9 GKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSV
              400       410       420       430       440       450

         530       540       550       560       570         
pF1KB9 EALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP
              460       470       480       490       500    

>>XP_006713514 (OMIM: 602304) PREDICTED: nuclear recepto  (448 aa)
 initn: 3188 init1: 3066 opt: 3066  Z-score: 2968.0  bits: 558.7 E(85289): 1.4e-158
Smith-Waterman score: 3066; 99.8% identity (100.0% similar) in 445 aa overlap (1-445:1-445)

               10        20        30        40        50        60
pF1KB9 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEVNAGGVIAYISSSSSASSPASCHSEGSENSFQSSSSSVPSSPNSSNSDTNGNPKNGDL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSGMVLLCKVCGDVASGFHYGVHAC
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB9 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRPKPQLEQENIKS
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB9 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDH
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB9 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CGNGLSSHFPCSESQQHLNGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPI
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB9 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGFSQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFA
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB9 KRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAG
       ::::::::::::::::::::::::.                                   
XP_006 KRIPGFRDLSQHDQVNLLKAGTFEIDLE                                
              430       440                                        

>>NP_068370 (OMIM: 602408) nuclear receptor subfamily 1   (614 aa)
 initn: 1836 init1: 910 opt: 1722  Z-score: 1667.6  bits: 318.6 E(85289): 3.8e-86
Smith-Waterman score: 1783; 51.1% identity (72.5% similar) in 614 aa overlap (4-577:9-611)

                    10           20        30        40         50 
pF1KB9      MEVNAGGVIAYISSSSSA---SSPASCHSEGSENSFQSSSSSVPSS-PNSSNSDT
               :.::::.::.::.:.   .:: : .:..:..:::: ... :.  : : ... 
NP_068 MTTLDSNNNTGGVITYIGSSGSSPSRTSPESLYSDNSNGSFQSLTQGCPTYFPPSPTGSL
               10        20        30        40        50        60

              60        70        80                             90
pF1KB9 NGNPKNGDLANIEGILKNDRIDCSMKTSKSSA--------PGM-------------TKSH
       . .:  . ...:   :..:    : ..:.::.        ::              .:: 
NP_068 TQDPARS-FGSIPPSLSDDGSPSSSSSSSSSSSSFYNGSPPGSLQVAMEDSSRVSPSKST
                70        80        90       100       110         

              100       110       120       130       140       150
pF1KB9 SGVTKFSGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMR
       :..::..:::::::::::::::::::::::::::::::::::::::::.:::::::::.:
NP_068 SNITKLNGMVLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVR
     120       130       140       150       160       170         

              160       170       180       190       200       210
pF1KB9 MNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQND
       .::::::::::::::::::::::::::::::::::::: ::::::. . :.:.:..   .
NP_068 INRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMN-LANNQLSSQCPLE
     180       190       200       210       220        230        

              220       230                240       250       260 
pF1KB9 TLVEHHEQTALPAQEQLRPKP---------QLEQENIKSSSPPSSDFAKEEVIGMVTRAH
       :   .:  :  :   .  : :         :. :. .     :: . . :.::..:.:::
NP_068 TSPTQHP-TPGPMGPSPPPAPVPSPLVGFSQFPQQ-LTPPRSPSPEPTVEDVISQVARAH
      240        250       260       270        280       290      

             270       280       290       300       310           
pF1KB9 KDTFMYNQEQQENSAESMQPQRGERIPKNMEQYNLNHDHCGNGLSSHFPCSESQQH---L
       .. : : ...  .:  ... ...   :     .  ... :  . ...   . .:.:   :
NP_068 REIFTYAHDKLGSSPGNFNANHASGSPPATTPHRWENQGCPPAPNDNNTLA-AQRHNEAL
        300       310       320       330       340        350     

      320       330       340       350       360          370     
pF1KB9 NGQFKGRNIMHYPNGHAICIANGHCMNFSNAYTQRVCDRVPIDGFSQNENK---NSYLCN
       ::  .. .   ::       :.  : . ::.  .:.:   :   ..  :.:   ::   .
NP_068 NGLRQAPS--SYPPTWPPGPAHHSCHQ-SNSNGHRLC---PTHVYAAPEGKAPANSPRQG
         360         370       380           390       400         

         380       390       400       410       420       430     
pF1KB9 TGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQV
       ..  . :.:::.  :.    .. .::::.:::::::::.:::::::.:::::::::::::
NP_068 NSKNVLLACPMNMYPHGRSGRTVQEIWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQV
     410       420       430       440       450       460         

         440       450       460       470       480       490     
pF1KB9 NLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNA
       .::::::::::::::::::..:..:: :::   ::...: .:: ::::..::.::::::.
NP_068 TLLKAGTFEVLMVRFASLFNVKDQTVMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNS
     470       480       490       500       510       520         

         500       510       520       530       540       550     
pF1KB9 LQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLL
       : :..::..::::::::::::::.::  ::: :::::.::::.:..::.: :.: :::::
NP_068 LALTEEELGLFTAVVLVSADRSGMENSASVEQLQETLLRALRALVLKNRPLETSRFTKLL
     530       540       550       560       570       580         

         560       570          
pF1KB9 LKLPDLRSLNNMHSEELLAFKVHP 
       :::::::.:::::::.::.:.:   
NP_068 LKLPDLRTLNNMHSEKLLSFRVDAQ
     590       600       610    

>>XP_011520181 (OMIM: 600825) PREDICTED: nuclear recepto  (376 aa)
 initn: 339 init1: 204 opt: 477  Z-score: 468.1  bits: 95.9 E(85289): 2.5e-19
Smith-Waterman score: 494; 32.5% identity (65.7% similar) in 335 aa overlap (271-579:19-349)

              250       260       270       280         290        
pF1KB9 SSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAESMQPQRGERI-PK-NMEQYNLN-
                                     ::..  ...:: ..: . :  :.   .:. 
XP_011             MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTE
                           10        20        30        40        

        300       310       320       330                    340   
pF1KB9 -HDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYP-------NG---HAIC---IANG--
        ::  .: ...: : . . .   ..:   .:.  :       ::   . ::    :.:  
XP_011 LHDDLSNYIDGHTPEGSKADSAVSSFY-LDIQPSPDQSGLDINGIKPEPICDYTPASGFF
       50        60        70         80        90       100       

              350       360       370            380       390     
pF1KB9 -HCMNFSNAYTQRVCDRVPIDGFSQNENKN-----SYLCNTGGRMHLVCPMSKSPYVDPH
        .: .:.:. :. . . . .. ..:: .:.     .:: .   ..     ...      .
XP_011 PYC-SFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQN
       110        120       130       140       150       160      

         400       410       420       430       440       450     
pF1KB9 KSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFD
       :. . .:.  ....: :.. :::::::: :: .: :.::. :::::..::...:.   ::
XP_011 KQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFD
        170       180       190       200       210       220      

         460       470       480       490       500       510     
pF1KB9 AKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSAD
       ... :: : .::  : : ..:.:  :... .:::...: ...:...:..::.: ::.:::
XP_011 SQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSAD
        230        240       250       260       270       280     

         520       530       540       550       560       570     
pF1KB9 RSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAF
       :: ...  ..: ::. .  ::. ...:::  : .:.:::. :.  ::.: . :.:.:.::
XP_011 RSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAF
         290       300       310        320       330       340    

                                       
pF1KB9 K-VHP                           
       : ..:                           
XP_011 KAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
          350       360       370      

>>XP_016877956 (OMIM: 600825) PREDICTED: nuclear recepto  (386 aa)
 initn: 388 init1: 204 opt: 477  Z-score: 467.9  bits: 95.9 E(85289): 2.5e-19
Smith-Waterman score: 500; 31.4% identity (64.1% similar) in 357 aa overlap (255-579:9-359)

          230       240       250       260       270          280 
pF1KB9 EQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQ---ENSAESMQP
                                     : ... ..:. .: . :.   ... .. : 
XP_016                       MSRDAVKFGRMSKKQRDS-LYAEVQKHRMQQQQRDHQQ
                                     10         20        30       

             290              300       310       320       330    
pF1KB9 QRGERIPKNMEQYNLN-------HDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYP---
       : ::  : .   ::..       ::  .: ...: : . . .   ..:   .:.  :   
XP_016 QPGEAEPLT-PTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFY-LDIQPSPDQS
        40         50        60        70        80         90     

                       340          350       360       370        
pF1KB9 ----NG---HAIC---IANG---HCMNFSNAYTQRVCDRVPIDGFSQNENKN-----SYL
           ::   . ::    :.:   .: .:.:. :. . . . .. ..:: .:.     .::
XP_016 GLDINGIKPEPICDYTPASGFFPYC-SFTNGETSPTVSMAELEHLAQNISKSHLETCQYL
         100       110       120        130       140       150    

           380       390       400       410       420       430   
pF1KB9 CNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHD
        .   ..     ...      .:. . .:.  ....: :.. :::::::: :: .: :.:
XP_016 REELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQND
          160       170       180       190       200       210    

           440       450       460       470       480       490   
pF1KB9 QVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKL
       :. :::::..::...:.   ::... :: : .::  : : ..:.:  :... .:::...:
XP_016 QIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSL
          220       230       240        250       260       270   

           500       510       520       530       540       550   
pF1KB9 NALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTK
        ...:...:..::.: ::.::::: ...  ..: ::. .  ::. ...:::  : .:.::
XP_016 CSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTK
           280       290       300       310       320        330  

           560       570                                     
pF1KB9 LLLKLPDLRSLNNMHSEELLAFK-VHP                           
       :. :.  ::.: . :.:.:.::: ..:                           
XP_016 LICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
            340       350       360       370       380      

>>XP_011520180 (OMIM: 600825) PREDICTED: nuclear recepto  (386 aa)
 initn: 388 init1: 204 opt: 477  Z-score: 467.9  bits: 95.9 E(85289): 2.5e-19
Smith-Waterman score: 500; 31.4% identity (64.1% similar) in 357 aa overlap (255-579:9-359)

          230       240       250       260       270          280 
pF1KB9 EQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQ---ENSAESMQP
                                     : ... ..:. .: . :.   ... .. : 
XP_011                       MSRDAVKFGRMSKKQRDS-LYAEVQKHRMQQQQRDHQQ
                                     10         20        30       

             290              300       310       320       330    
pF1KB9 QRGERIPKNMEQYNLN-------HDHCGNGLSSHFPCSESQQHLNGQFKGRNIMHYP---
       : ::  : .   ::..       ::  .: ...: : . . .   ..:   .:.  :   
XP_011 QPGEAEPLT-PTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFY-LDIQPSPDQS
        40         50        60        70        80         90     

                       340          350       360       370        
pF1KB9 ----NG---HAIC---IANG---HCMNFSNAYTQRVCDRVPIDGFSQNENKN-----SYL
           ::   . ::    :.:   .: .:.:. :. . . . .. ..:: .:.     .::
XP_011 GLDINGIKPEPICDYTPASGFFPYC-SFTNGETSPTVSMAELEHLAQNISKSHLETCQYL
         100       110       120        130       140       150    

           380       390       400       410       420       430   
pF1KB9 CNTGGRMHLVCPMSKSPYVDPHKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHD
        .   ..     ...      .:. . .:.  ....: :.. :::::::: :: .: :.:
XP_011 REELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQND
          160       170       180       190       200       210    

           440       450       460       470       480       490   
pF1KB9 QVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKL
       :. :::::..::...:.   ::... :: : .::  : : ..:.:  :... .:::...:
XP_011 QIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSL
          220       230       240        250       260       270   

           500       510       520       530       540       550   
pF1KB9 NALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTK
        ...:...:..::.: ::.::::: ...  ..: ::. .  ::. ...:::  : .:.::
XP_011 CSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTK
           280       290       300       310       320        330  

           560       570                                     
pF1KB9 LLLKLPDLRSLNNMHSEELLAFK-VHP                           
       :. :.  ::.: . :.:.:.::: ..:                           
XP_011 LICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
            340       350       360       370       380      

>>NP_803184 (OMIM: 600409) peroxisome proliferator-activ  (361 aa)
 initn: 589 init1: 228 opt: 462  Z-score: 453.9  bits: 93.2 E(85289): 1.5e-18
Smith-Waterman score: 462; 45.8% identity (73.6% similar) in 144 aa overlap (79-212:46-187)

       50        60        70        80          90         100    
pF1KB9 SDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPG--MTKSHSGVTKFS--GMVLLCK
                                     :.::.:   . . . :    :  .. . :.
NP_803 EKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECR
          20        30        40        50        60        70     

          110       120       130       140       150       160    
pF1KB9 VCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKC
       :::: ::::::::::::::::::::.:.....:.:: ..  :.:.. :::.:: :::.::
NP_803 VCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERS--CKIQKKNRNKCQYCRFQKC
          80        90       100       110         120       130   

          170       180       190       200             210        
pF1KB9 LSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ------FSGHLQNDTLVEHHEQ
       :..:::..:.::::.:. ::....  . .   ...: :      :: :. :  :      
NP_803 LALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMT
           140       150       160       170       180       190   

      220       230       240       250       260       270        
pF1KB9 TALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAES
                                                                   
NP_803 KKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTT
           200       210       220       230       240       250   

>--
 initn: 211 init1: 124 opt: 196  Z-score: 196.9  bits: 45.7 E(85289): 0.00031
Smith-Waterman score: 196; 34.1% identity (69.1% similar) in 123 aa overlap (394-512:237-357)

           370       380       390         400       410       420 
pF1KB9 SQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHK--SGHEIWEEFSMSFTPAVKEVVEFAK
                                     :.:  : : .. . . . . .:.:..::::
NP_803 HTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVH-VFYRCQCTTVETVRELTEFAK
        210       220       230       240        250       260     

             430       440       450       460       470           
pF1KB9 RIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGA--
        ::.: .:  .:::.::: :. :.... .::. .     :.  ::   . . :.:.    
NP_803 SIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGF-VTREFLRSLRKPF
         270       280       290       300       310        320    

     480       490       500       510       520       530         
pF1KB9 GDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTL
       .:...  :::. :.:::.:.: ...:: :....                           
NP_803 SDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGGE                       
          330       340       350       360                        

     540       550       560       570         
pF1KB9 IMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP

>>XP_016866464 (OMIM: 600409) PREDICTED: peroxisome prol  (365 aa)
 initn: 589 init1: 228 opt: 462  Z-score: 453.8  bits: 93.2 E(85289): 1.5e-18
Smith-Waterman score: 462; 45.8% identity (73.6% similar) in 144 aa overlap (79-212:46-187)

       50        60        70        80          90         100    
pF1KB9 SDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPG--MTKSHSGVTKFS--GMVLLCK
                                     :.::.:   . . . :    :  .. . :.
XP_016 EKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECR
          20        30        40        50        60        70     

          110       120       130       140       150       160    
pF1KB9 VCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKC
       :::: ::::::::::::::::::::.:.....:.:: ..  :.:.. :::.:: :::.::
XP_016 VCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERS--CKIQKKNRNKCQYCRFQKC
          80        90       100       110         120       130   

          170       180       190       200             210        
pF1KB9 LSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQ------FSGHLQNDTLVEHHEQ
       :..:::..:.::::.:. ::....  . .   ...: :      :: :. :  :      
XP_016 LALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMT
           140       150       160       170       180       190   

      220       230       240       250       260       270        
pF1KB9 TALPAQEQLRPKPQLEQENIKSSSPPSSDFAKEEVIGMVTRAHKDTFMYNQEQQENSAES
                                                                   
XP_016 KKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTT
           200       210       220       230       240       250   

>--
 initn: 211 init1: 124 opt: 196  Z-score: 196.8  bits: 45.7 E(85289): 0.00032
Smith-Waterman score: 196; 34.1% identity (69.1% similar) in 123 aa overlap (394-512:237-357)

           370       380       390         400       410       420 
pF1KB9 SQNENKNSYLCNTGGRMHLVCPMSKSPYVDPHK--SGHEIWEEFSMSFTPAVKEVVEFAK
                                     :.:  : : .. . . . . .:.:..::::
XP_016 HTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVH-VFYRCQCTTVETVRELTEFAK
        210       220       230       240        250       260     

             430       440       450       460       470           
pF1KB9 RIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLFDAKERTVTFLSGKKYSVDDLHSMGA--
        ::.: .:  .:::.::: :. :.... .::. .     :.  ::   . . :.:.    
XP_016 SIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGF-VTREFLRSLRKPF
         270       280       290       300       310        320    

     480       490       500       510       520       530         
pF1KB9 GDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSADRSGIENVNSVEALQETLIRALRTL
       .:...  :::. :.:::.:.: ...:: :....                           
XP_016 SDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGAAAEDG                   
          330       340       350       360                        

     540       550       560       570         
pF1KB9 IMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLAFKVHP

>>XP_011532146 (OMIM: 125853,601487,601665,604367,609338  (250 aa)
 initn: 456 init1: 238 opt: 457  Z-score: 451.4  bits: 92.3 E(85289): 2.1e-18
Smith-Waterman score: 457; 40.1% identity (68.7% similar) in 182 aa overlap (25-198:28-204)

                  10        20        30         40        50      
pF1KB9    MEVNAGGVIAYISSSSSASSPASCHSEGSE-NSFQSSSSSVPSSPNSSNSD-TNGNP
                                  ::.. . . : . . :  :.:.  .   :  .:
XP_011 MTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDP
               10        20        30        40        50        60

          60        70        80        90             100         
pF1KB9 KNGDLANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKF------SGMVLLCKVCGDV
           .:. .  :: .. . ..:.  .: : .... .  .:       : :.. :.:::: 
XP_011 V---VADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDK
                  70        80        90       100       110       

     110       120       130       140       150       160         
pF1KB9 ASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQCRFKKCLSVGM
       ::::::::::::::::::::.:. .. : .:  . :: : . .::.:: :::.:::.:::
XP_011 ASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCRFQKCLAVGM
       120       130       140         150       160       170     

     170       180       190       200       210       220         
pF1KB9 SRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQNDTLVEHHEQTALPAQEQLRP
       :..:.::::.:. ::...: :..: .  .                               
XP_011 SHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARA
         180       190       200       210       220       230     




579 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Nov  3 23:03:45 2016 done: Thu Nov  3 23:03:46 2016
 Total Scan time: 10.990 Total Display time:  0.090

Function used was FASTA [36.3.4 Apr, 2011]
Inquiries or Suggestions ?
Send a message to flexiclone AT kazusagt.com