FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9213, 839 aa 1>>>pF1KB9213 839 - 839 aa - 839 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4611+/-0.00111; mu= 10.2925+/- 0.066 mean_var=101.8011+/-20.311, 0's: 0 Z-trim(105.9): 38 B-trim: 284 in 1/48 Lambda= 0.127115 statistics sampled from 8656 (8666) to 8656 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.266), width: 16 Scan time: 4.440 The best scores are: opt bits E(32554) CCDS42413.1 PPP4R1 gene_id:9989|Hs108|chr18 ( 933) 4214 783.9 0 CCDS42412.1 PPP4R1 gene_id:9989|Hs108|chr18 ( 950) 4214 783.9 0 >>CCDS42413.1 PPP4R1 gene_id:9989|Hs108|chr18 (933 aa) initn: 4308 init1: 4214 opt: 4214 Z-score: 4176.1 bits: 783.9 E(32554): 0 Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:63-933) 50 60 70 80 90 100 pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ :::::::::::::::::::::::::::::: CCDS42 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ 40 50 60 70 80 90 110 120 130 140 150 160 pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV 100 110 120 130 140 150 170 180 190 pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA---------------------------------- :::::::::::::::::::::::::: CCDS42 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV 160 170 180 190 200 210 pF1KB9 ------------------------------------------------------------ CCDS42 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR 220 230 240 250 260 270 200 210 220 230 pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR ::::::::::::::::::::::::::::::::::::::::::: CCDS42 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR 280 290 300 310 320 330 240 250 260 270 280 290 pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT 340 350 360 370 380 390 300 310 320 330 340 350 pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD 400 410 420 430 440 450 360 370 380 390 400 410 pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV 460 470 480 490 500 510 420 430 440 450 460 470 pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH 520 530 540 550 560 570 480 490 500 510 520 530 pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL 580 590 600 610 620 630 540 550 560 570 580 590 pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG 640 650 660 670 680 690 600 610 620 630 640 650 pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL 700 710 720 730 740 750 660 670 680 690 700 710 pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV 760 770 780 790 800 810 720 730 740 750 760 770 pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL 820 830 840 850 860 870 780 790 800 810 820 830 pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST 880 890 900 910 920 930 pF1KB9 Y : CCDS42 Y >>CCDS42412.1 PPP4R1 gene_id:9989|Hs108|chr18 (950 aa) initn: 4214 init1: 4214 opt: 4214 Z-score: 4176.0 bits: 783.9 E(32554): 0 Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:80-950) 50 60 70 80 90 100 pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ :::::::::::::::::::::::::::::: CCDS42 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ 50 60 70 80 90 100 110 120 130 140 150 160 pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV 110 120 130 140 150 160 170 180 190 pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA---------------------------------- :::::::::::::::::::::::::: CCDS42 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV 170 180 190 200 210 220 pF1KB9 ------------------------------------------------------------ CCDS42 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR 230 240 250 260 270 280 200 210 220 230 pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR ::::::::::::::::::::::::::::::::::::::::::: CCDS42 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR 290 300 310 320 330 340 240 250 260 270 280 290 pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT 350 360 370 380 390 400 300 310 320 330 340 350 pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD 410 420 430 440 450 460 360 370 380 390 400 410 pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV 470 480 490 500 510 520 420 430 440 450 460 470 pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH 530 540 550 560 570 580 480 490 500 510 520 530 pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL 590 600 610 620 630 640 540 550 560 570 580 590 pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG 650 660 670 680 690 700 600 610 620 630 640 650 pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL 710 720 730 740 750 760 660 670 680 690 700 710 pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV 770 780 790 800 810 820 720 730 740 750 760 770 pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL 830 840 850 860 870 880 780 790 800 810 820 830 pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST 890 900 910 920 930 940 pF1KB9 Y : CCDS42 Y 950 >-- initn: 506 init1: 506 opt: 506 Z-score: 500.9 bits: 103.9 E(32554): 1.4e-21 Smith-Waterman score: 506; 100.0% identity (100.0% similar) in 79 aa overlap (1-79:1-79) 10 20 30 40 50 60 pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN ::::::::::::::::::: CCDS42 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN 70 80 90 100 110 120 839 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:06:36 2016 done: Thu Nov 3 23:06:36 2016 Total Scan time: 4.440 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]