FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9213, 839 aa
1>>>pF1KB9213 839 - 839 aa - 839 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.8654+/-0.000426; mu= 8.0129+/- 0.026
mean_var=117.7577+/-23.693, 0's: 0 Z-trim(113.4): 24 B-trim: 129 in 2/53
Lambda= 0.118190
statistics sampled from 22667 (22691) to 22667 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.266), width: 16
Scan time: 13.240
The best scores are: opt bits E(85289)
XP_011524081 (OMIM: 604908) PREDICTED: serine/thre ( 891) 5443 939.9 0
XP_016881594 (OMIM: 604908) PREDICTED: serine/thre ( 949) 4223 731.9 3.3e-210
XP_016881595 (OMIM: 604908) PREDICTED: serine/thre ( 861) 4214 730.3 8.8e-210
XP_016881596 (OMIM: 604908) PREDICTED: serine/thre ( 861) 4214 730.3 8.8e-210
NP_005125 (OMIM: 604908) serine/threonine-protein ( 933) 4214 730.3 9.5e-210
NP_001035847 (OMIM: 604908) serine/threonine-prote ( 950) 4214 730.3 9.6e-210
XP_011524078 (OMIM: 604908) PREDICTED: serine/thre ( 985) 4214 730.3 1e-209
XP_011524077 (OMIM: 604908) PREDICTED: serine/thre (1002) 4214 730.3 1e-209
NP_055040 (OMIM: 605983,616362) serine/threonine-p ( 589) 179 42.3 0.008
XP_016882418 (OMIM: 605983,616362) PREDICTED: seri ( 410) 176 41.7 0.0082
NP_001171034 (OMIM: 211980,603113) serine/threonin ( 474) 176 41.7 0.0093
>>XP_011524081 (OMIM: 604908) PREDICTED: serine/threonin (891 aa)
initn: 5443 init1: 5443 opt: 5443 Z-score: 5019.5 bits: 939.9 E(85289): 0
Smith-Waterman score: 5443; 100.0% identity (100.0% similar) in 836 aa overlap (4-839:56-891)
10 20 30
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIP
::::::::::::::::::::::::::::::
XP_011 GGEAALPPRGGGTPAPTTSEPPPAPDRRRHLSLLQEDLQEDADGFGVDDYSSESDVIIIP
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB9 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB9 ALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAVRQAAFQSLGPFISTFAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAVRQAAFQSLGPFISTFAN
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB9 PSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTME
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB9 DHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQD
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB9 SALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATR
390 400 410 420 430 440
400 410 420 430 440 450
pF1KB9 KELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELP
450 460 470 480 490 500
460 470 480 490 500 510
pF1KB9 NCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQ
510 520 530 540 550 560
520 530 540 550 560 570
pF1KB9 YLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLA
570 580 590 600 610 620
580 590 600 610 620 630
pF1KB9 FSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQL
630 640 650 660 670 680
640 650 660 670 680 690
pF1KB9 QEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKL
690 700 710 720 730 740
700 710 720 730 740 750
pF1KB9 VSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAV
750 760 770 780 790 800
760 770 780 790 800 810
pF1KB9 HLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSD
810 820 830 840 850 860
820 830
pF1KB9 VKYFASIHPASTKISEDAMSTASSTY
::::::::::::::::::::::::::
XP_011 VKYFASIHPASTKISEDAMSTASSTY
870 880 890
>>XP_016881594 (OMIM: 604908) PREDICTED: serine/threonin (949 aa)
initn: 4223 init1: 4223 opt: 4223 Z-score: 3894.8 bits: 731.9 E(85289): 3.3e-210
Smith-Waterman score: 5168; 93.3% identity (93.3% similar) in 871 aa overlap (27-839:79-949)
10 20 30 40 50
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAA
::::::::::::::::::::::::::::::
XP_016 APDRRRHLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAA
50 60 70 80 90 100
60 70 80 90 100 110
pF1KB9 SENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALF
110 120 130 140 150 160
120 130 140 150 160 170
pF1KB9 CQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPV
170 180 190 200 210 220
180 190
pF1KB9 LIELTAPDSNDDVKTEAVA-----------------------------------------
:::::::::::::::::::
XP_016 LIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAAN
230 240 250 260 270 280
200 210 220 230
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
:::::::::::::::::::::::::::::::::::::::::::
XP_016 FGDICSVVGQQATEEMLVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
290 300 310 320 330 340
240 250 260 270 280 290
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
350 360 370 380 390 400
300 310 320 330 340 350
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
410 420 430 440 450 460
360 370 380 390 400 410
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
470 480 490 500 510 520
420 430 440 450 460 470
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
530 540 550 560 570 580
480 490 500 510 520 530
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
590 600 610 620 630 640
540 550 560 570 580 590
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
650 660 670 680 690 700
600 610 620 630 640 650
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
710 720 730 740 750 760
660 670 680 690 700 710
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
770 780 790 800 810 820
720 730 740 750 760 770
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
830 840 850 860 870 880
780 790 800 810 820 830
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
890 900 910 920 930 940
pF1KB9 Y
:
XP_016 Y
>>XP_016881595 (OMIM: 604908) PREDICTED: serine/threonin (861 aa)
initn: 4214 init1: 4214 opt: 4214 Z-score: 3887.2 bits: 730.3 E(85289): 8.8e-210
Smith-Waterman score: 4604; 86.9% identity (87.0% similar) in 853 aa overlap (98-839:9-861)
70 80 90 100 110 120
pF1KB9 RSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYA
.:::::::::::::::::::::::::::::
XP_016 MLQVRTYLTEPTVRAELMEQVPHIALFCQENRPSIPYA
10 20 30
130 140 150 160 170 180
pF1KB9 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
40 50 60 70 80 90
190
pF1KB9 DVKTEAVA----------------------------------------------------
::::::::
XP_016 DVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQ
100 110 120 130 140 150
pF1KB9 -----------------------------------------------------------V
:
XP_016 ATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWV
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB9 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB9 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB9 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB9 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
400 410 420 430 440 450
440 450 460 470 480 490
pF1KB9 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
460 470 480 490 500 510
500 510 520 530 540 550
pF1KB9 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
520 530 540 550 560 570
560 570 580 590 600 610
pF1KB9 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
580 590 600 610 620 630
620 630 640 650 660 670
pF1KB9 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
640 650 660 670 680 690
680 690 700 710 720 730
pF1KB9 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
700 710 720 730 740 750
740 750 760 770 780 790
pF1KB9 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
760 770 780 790 800 810
800 810 820 830
pF1KB9 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
:::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
820 830 840 850 860
>>XP_016881596 (OMIM: 604908) PREDICTED: serine/threonin (861 aa)
initn: 4214 init1: 4214 opt: 4214 Z-score: 3887.2 bits: 730.3 E(85289): 8.8e-210
Smith-Waterman score: 4604; 86.9% identity (87.0% similar) in 853 aa overlap (98-839:9-861)
70 80 90 100 110 120
pF1KB9 RSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYA
.:::::::::::::::::::::::::::::
XP_016 MLQVRTYLTEPTVRAELMEQVPHIALFCQENRPSIPYA
10 20 30
130 140 150 160 170 180
pF1KB9 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSND
40 50 60 70 80 90
190
pF1KB9 DVKTEAVA----------------------------------------------------
::::::::
XP_016 DVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQ
100 110 120 130 140 150
pF1KB9 -----------------------------------------------------------V
:
XP_016 ATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWV
160 170 180 190 200 210
200 210 220 230 240 250
pF1KB9 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNRTRDQEAPEDVQVRPEDTP
220 230 240 250 260 270
260 270 280 290 300 310
pF1KB9 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCTLSSESHQEAASNENDKKP
280 290 300 310 320 330
320 330 340 350 360 370
pF1KB9 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLDIELEQNSGGKPSPEGPEE
340 350 360 370 380 390
380 390 400 410 420 430
pF1KB9 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEVLSAALRASSLDAHEETIS
400 410 420 430 440 450
440 450 460 470 480 490
pF1KB9 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDE
460 470 480 490 500 510
500 510 520 530 540 550
pF1KB9 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRET
520 530 540 550 560 570
560 570 580 590 600 610
pF1KB9 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHD
580 590 600 610 620 630
620 630 640 650 660 670
pF1KB9 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIAL
640 650 660 670 680 690
680 690 700 710 720 730
pF1KB9 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFV
700 710 720 730 740 750
740 750 760 770 780 790
pF1KB9 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQ
760 770 780 790 800 810
800 810 820 830
pF1KB9 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
:::::::::::::::::::::::::::::::::::::::::::
XP_016 EAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASSTY
820 830 840 850 860
>>NP_005125 (OMIM: 604908) serine/threonine-protein phos (933 aa)
initn: 4308 init1: 4214 opt: 4214 Z-score: 3886.7 bits: 730.3 E(85289): 9.5e-210
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:63-933)
50 60 70 80 90 100
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
::::::::::::::::::::::::::::::
NP_005 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
40 50 60 70 80 90
110 120 130 140 150 160
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
100 110 120 130 140 150
170 180 190
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
::::::::::::::::::::::::::
NP_005 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
160 170 180 190 200 210
pF1KB9 ------------------------------------------------------------
NP_005 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
220 230 240 250 260 270
200 210 220 230
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
:::::::::::::::::::::::::::::::::::::::::::
NP_005 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
280 290 300 310 320 330
240 250 260 270 280 290
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
340 350 360 370 380 390
300 310 320 330 340 350
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
400 410 420 430 440 450
360 370 380 390 400 410
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
460 470 480 490 500 510
420 430 440 450 460 470
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
520 530 540 550 560 570
480 490 500 510 520 530
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
580 590 600 610 620 630
540 550 560 570 580 590
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
640 650 660 670 680 690
600 610 620 630 640 650
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
700 710 720 730 740 750
660 670 680 690 700 710
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
760 770 780 790 800 810
720 730 740 750 760 770
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
820 830 840 850 860 870
780 790 800 810 820 830
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
880 890 900 910 920 930
pF1KB9 Y
:
NP_005 Y
>--
initn: 379 init1: 285 opt: 285 Z-score: 266.0 bits: 60.4 E(85289): 4.5e-08
Smith-Waterman score: 349; 77.2% identity (78.5% similar) in 79 aa overlap (1-79:1-62)
10 20 30 40 50 60
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI
::::::::::::::::: .:::::::::::::::::::::::::
NP_005 MADLSLLQEDLQEDADG-----------------SLDFVSQDEMLTPLGRLDKYAASENI
10 20 30 40
70 80 90 100 110 120
pF1KB9 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
:::::::::::::::::::
NP_005 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
50 60 70 80 90 100
>>NP_001035847 (OMIM: 604908) serine/threonine-protein p (950 aa)
initn: 4214 init1: 4214 opt: 4214 Z-score: 3886.5 bits: 730.3 E(85289): 9.6e-210
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:80-950)
50 60 70 80 90 100
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
::::::::::::::::::::::::::::::
NP_001 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
110 120 130 140 150 160
170 180 190
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
::::::::::::::::::::::::::
NP_001 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
170 180 190 200 210 220
pF1KB9 ------------------------------------------------------------
NP_001 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
230 240 250 260 270 280
200 210 220 230
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
:::::::::::::::::::::::::::::::::::::::::::
NP_001 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
290 300 310 320 330 340
240 250 260 270 280 290
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
350 360 370 380 390 400
300 310 320 330 340 350
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
410 420 430 440 450 460
360 370 380 390 400 410
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
470 480 490 500 510 520
420 430 440 450 460 470
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
530 540 550 560 570 580
480 490 500 510 520 530
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
590 600 610 620 630 640
540 550 560 570 580 590
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
650 660 670 680 690 700
600 610 620 630 640 650
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
710 720 730 740 750 760
660 670 680 690 700 710
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
770 780 790 800 810 820
720 730 740 750 760 770
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
830 840 850 860 870 880
780 790 800 810 820 830
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
890 900 910 920 930 940
pF1KB9 Y
:
NP_001 Y
950
>--
initn: 506 init1: 506 opt: 506 Z-score: 469.5 bits: 98.1 E(85289): 2.1e-19
Smith-Waterman score: 506; 100.0% identity (100.0% similar) in 79 aa overlap (1-79:1-79)
10 20 30 40 50 60
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
:::::::::::::::::::
NP_001 FNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQEN
70 80 90 100 110 120
>>XP_011524078 (OMIM: 604908) PREDICTED: serine/threonin (985 aa)
initn: 4288 init1: 4214 opt: 4214 Z-score: 3886.3 bits: 730.3 E(85289): 1e-209
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:115-985)
50 60 70 80 90 100
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
::::::::::::::::::::::::::::::
XP_011 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
150 160 170 180 190 200
170 180 190
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
::::::::::::::::::::::::::
XP_011 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
210 220 230 240 250 260
pF1KB9 ------------------------------------------------------------
XP_011 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
270 280 290 300 310 320
200 210 220 230
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
:::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
330 340 350 360 370 380
240 250 260 270 280 290
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
390 400 410 420 430 440
300 310 320 330 340 350
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
450 460 470 480 490 500
360 370 380 390 400 410
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
510 520 530 540 550 560
420 430 440 450 460 470
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
570 580 590 600 610 620
480 490 500 510 520 530
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
630 640 650 660 670 680
540 550 560 570 580 590
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
690 700 710 720 730 740
600 610 620 630 640 650
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
750 760 770 780 790 800
660 670 680 690 700 710
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
810 820 830 840 850 860
720 730 740 750 760 770
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
870 880 890 900 910 920
780 790 800 810 820 830
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
930 940 950 960 970 980
pF1KB9 Y
:
XP_011 Y
>--
initn: 359 init1: 285 opt: 285 Z-score: 265.6 bits: 60.4 E(85289): 4.7e-08
Smith-Waterman score: 329; 76.3% identity (77.6% similar) in 76 aa overlap (4-79:56-114)
10 20 30
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIP
::::::::::::::
XP_011 GGEAALPPRGGGTPAPTTSEPPPAPDRRRHLSLLQEDLQEDADG----------------
30 40 50 60
40 50 60 70 80 90
pF1KB9 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
.::::::::::::::::::::::::::::::::::::::::::::
XP_011 -SLDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB9 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
XP_011 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
130 140 150 160 170 180
>>XP_011524077 (OMIM: 604908) PREDICTED: serine/threonin (1002 aa)
initn: 4214 init1: 4214 opt: 4214 Z-score: 3886.1 bits: 730.3 E(85289): 1e-209
Smith-Waterman score: 4725; 87.3% identity (87.3% similar) in 871 aa overlap (80-839:132-1002)
50 60 70 80 90 100
pF1KB9 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
::::::::::::::::::::::::::::::
XP_011 RLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQ
110 120 130 140 150 160
110 120 130 140 150 160
pF1KB9 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDV
170 180 190 200 210 220
170 180 190
pF1KB9 ETKVCPVLIELTAPDSNDDVKTEAVA----------------------------------
::::::::::::::::::::::::::
XP_011 ETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHV
230 240 250 260 270 280
pF1KB9 ------------------------------------------------------------
XP_011 RKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRR
290 300 310 320 330 340
200 210 220 230
pF1KB9 -----------------VRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
:::::::::::::::::::::::::::::::::::::::::::
XP_011 TKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQYFKEESKSSEEMSVENKNR
350 360 370 380 390 400
240 250 260 270 280 290
pF1KB9 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TRDQEAPEDVQVRPEDTPSDLSVSNSSVILENTMEDHAAEASGKPLGEISVPLDSSLLCT
410 420 430 440 450 460
300 310 320 330 340 350
pF1KB9 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSSESHQEAASNENDKKPGNYKSMLRPEVGTTSQDSALLDQELYNSFHFWRTPLPEIDLD
470 480 490 500 510 520
360 370 380 390 400 410
pF1KB9 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVKAQVEV
530 540 550 560 570 580
420 430 440 450 460 470
pF1KB9 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKINQEDSVPLISDAVENMDSTLH
590 600 610 620 630 640
480 490 500 510 520 530
pF1KB9 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YIHSDSDLSNNSSFSPDEERRTKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSL
650 660 670 680 690 700
540 550 560 570 580 590
pF1KB9 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNG
710 720 730 740 750 760
600 610 620 630 640 650
pF1KB9 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILL
770 780 790 800 810 820
660 670 680 690 700 710
pF1KB9 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHAATPPTFGVDLINELV
830 840 850 860 870 880
720 730 740 750 760 770
pF1KB9 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTL
890 900 910 920 930 940
780 790 800 810 820 830
pF1KB9 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPASTKISEDAMSTASST
950 960 970 980 990 1000
pF1KB9 Y
:
XP_011 Y
>--
initn: 486 init1: 486 opt: 486 Z-score: 450.7 bits: 94.7 E(85289): 2.3e-18
Smith-Waterman score: 486; 100.0% identity (100.0% similar) in 76 aa overlap (4-79:56-131)
10 20 30
pF1KB9 MADLSLLQEDLQEDADGFGVDDYSSESDVIIIP
::::::::::::::::::::::::::::::
XP_011 GGEAALPPRGGGTPAPTTSEPPPAPDRRRHLSLLQEDLQEDADGFGVDDYSSESDVIIIP
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB9 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISR
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB9 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
XP_011 LADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKFLLPIVVRYLADQNNQVRKTSQA
150 160 170 180 190 200
>>NP_055040 (OMIM: 605983,616362) serine/threonine-prote (589 aa)
initn: 195 init1: 113 opt: 179 Z-score: 171.7 bits: 42.3 E(85289): 0.008
Smith-Waterman score: 264; 24.8% identity (53.6% similar) in 412 aa overlap (386-780:156-546)
360 370 380 390 400 410
pF1KB9 DLDIELEQNSGGKPSPEGPEEESEGPVPSSPNITMATRKELEEMIENLEPHIDDPDVK-A
: .. :.. ::.....:: : : :. :
NP_055 AHFVPLVKRLAGGDWFTSRTSACGLFSVCYPRVSSAVKAELRQYFRNLCSD-DTPMVRRA
130 140 150 160 170 180
420 430 440 450 460
pF1KB9 QVEVLSAALRASSLD-AHEETISIEKR--SDLQDELDINELPNCKIN------QED----
. :. .. :: .. : : . . :: :: . . . : .: :::
NP_055 AASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEAC-VNIAQLLPQEDLEAL
190 200 210 220 230 240
470 480 490 500 510
pF1KB9 SVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVP--QALLDQYLSMTD
.: . .:.:. . ..:. .:. ... .:. ::. :.:: : :. . . .
NP_055 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGPE---ITKT-DLVPAFQNLMKDCEAEVR
250 260 270 280 290
520 530 540 550 560 570
pF1KB9 PSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHEL
. .. : . : .: .. : :..: :.:: . .:. .:: : :
NP_055 AAASHKVKEFCENLSADCRENVIMS---QILPCIKE----LVSDANQHVKSALASVIMGL
300 310 320 330 340 350
580 590 600 610 620 630
pF1KB9 AVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLV
. ::: . : :.:.: . ::: :::......: ... : . . : :.
NP_055 SPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELA
360 370 380 390 400 410
640 650 660 670 680 690
pF1KB9 TDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMV
: .:: : . : . :: . . . : . . .:.: ..: . . ....:
NP_055 EDA--KWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLV
420 430 440 450 460 470
700 710 720 730 740 750
pF1KB9 KKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPH
.:. . .: ... : :.. :.. .: : .:. . : .: . :..:
NP_055 EKFGKEWAHA---TIIPKVLAMSGD-PNYLHRMTTLF-CINVLSEVC-GQDITTKHMLPT
480 490 500 510 520
760 770 780 790 800 810
pF1KB9 LLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYFA
.: .:.: : ::: .::.:..
NP_055 VLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALT
530 540 550 560 570 580
>>XP_016882418 (OMIM: 605983,616362) PREDICTED: serine/t (410 aa)
initn: 193 init1: 113 opt: 176 Z-score: 171.5 bits: 41.7 E(85289): 0.0082
Smith-Waterman score: 236; 24.6% identity (53.0% similar) in 353 aa overlap (441-780:35-367)
420 430 440 450 460
pF1KB9 DVKAQVEVLSAALRASSLDAHEETISIEKRSDLQDELDINELPNCKIN------QED---
:: :: . . . : .: :::
XP_016 AAASKLGEFAKVLELDNVKSEIIPMFSNLASDEQDSVRLLAVEAC-VNIAQLLPQEDLEA
10 20 30 40 50 60
470 480 490 500 510
pF1KB9 -SVPLISDAVENMDSTLHYIHSDSDLSNNSSFSPDEERRTKVQDVVP--QALLDQYLSMT
.: . .:.:. . ..:. .:. ... .: : .: :.:: : :. . . .
XP_016 LVMPTLRQAAEDKSWRVRYMVADKFTELQKAVGP-EITKT---DLVPAFQNLMKDCEAEV
70 80 90 100 110
520 530 540 550 560 570
pF1KB9 DPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHE
. .. : . : .: .. : :..: :.:: . .:. .:: :
XP_016 RAAASHKVKEFCENLSADCRENVIMS---QILPCIKE----LVSDANQHVKSALASVIMG
120 130 140 150 160 170
580 590 600 610 620 630
pF1KB9 LAVILGDQLTAADLVPIFNGFLKD-LDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFL
:. ::: . : :.:.: . ::: :::......: ... : . . : :
XP_016 LSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVEL
180 190 200 210 220 230
640 650 660 670 680 690
pF1KB9 VTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEM
. : .:: : . : . :: . . . : . . .:.: ..: . . ....
XP_016 AEDA--KWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKL
240 250 260 270 280 290
700 710 720 730 740 750
pF1KB9 VKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMP
:.:. . .: ... : :.. :.. .: : .:. . : .: . :..:
XP_016 VEKFGKEWAH---ATIIPKVLAMSGD-PNYLHRMTTLF-CINVLSEVC-GQDITTKHMLP
300 310 320 330 340
760 770 780 790 800 810
pF1KB9 HLLTLANDRVPNVRVLLAKTLRQTLLEKDYFLASASCHQEAVEQTIMALQMDRDSDVKYF
.: .:.: : ::: .::.:..
XP_016 TVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDVDVKYFAQEAL
350 360 370 380 390 400
839 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:06:37 2016 done: Thu Nov 3 23:06:38 2016
Total Scan time: 13.240 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]