FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9239, 1430 aa 1>>>pF1KB9239 1430 - 1430 aa - 1430 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.0264+/-0.00198; mu= -0.8089+/- 0.113 mean_var=436.4045+/-96.698, 0's: 0 Z-trim(104.7): 759 B-trim: 0 in 0/50 Lambda= 0.061395 statistics sampled from 7195 (8045) to 7195 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.247), width: 16 Scan time: 4.980 The best scores are: opt bits E(32554) CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430) 9549 863.2 0 CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 ( 370) 1656 163.4 1.1e-39 CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 ( 454) 1543 153.5 1.3e-36 CCDS43141.1 MYLK gene_id:4638|Hs108|chr3 (1845) 913 98.4 2e-19 CCDS46896.1 MYLK gene_id:4638|Hs108|chr3 (1914) 913 98.5 2e-19 CCDS2315.1 STK17B gene_id:9262|Hs108|chr2 ( 372) 865 93.3 1.4e-18 CCDS5470.1 STK17A gene_id:9263|Hs108|chr7 ( 414) 857 92.7 2.5e-18 CCDS34330.1 MYLK4 gene_id:340156|Hs108|chr6 ( 388) 823 89.6 1.9e-17 CCDS76861.1 MYLK3 gene_id:91807|Hs108|chr16 ( 478) 817 89.2 3.2e-17 CCDS10723.2 MYLK3 gene_id:91807|Hs108|chr16 ( 819) 817 89.5 4.4e-17 CCDS13191.1 MYLK2 gene_id:85366|Hs108|chr20 ( 596) 789 86.8 2e-16 CCDS3028.1 KALRN gene_id:8997|Hs108|chr3 (1289) 796 87.9 2.1e-16 CCDS7092.1 CAMK1D gene_id:57118|Hs108|chr10 ( 357) 754 83.4 1.3e-15 CCDS7091.1 CAMK1D gene_id:57118|Hs108|chr10 ( 385) 752 83.3 1.5e-15 CCDS2582.1 CAMK1 gene_id:8536|Hs108|chr3 ( 370) 736 81.9 3.9e-15 CCDS3883.1 TRIO gene_id:7204|Hs108|chr5 (3097) 757 84.9 4e-15 CCDS4103.1 CAMK4 gene_id:814|Hs108|chr5 ( 473) 733 81.7 5.4e-15 CCDS48189.1 PNCK gene_id:139728|Hs108|chrX ( 360) 730 81.3 5.5e-15 CCDS35503.2 PNCK gene_id:139728|Hs108|chrX ( 426) 730 81.4 6.1e-15 CCDS43064.1 DCLK3 gene_id:85443|Hs108|chr3 ( 648) 716 80.4 1.9e-14 CCDS1486.1 CAMK1G gene_id:57172|Hs108|chr1 ( 476) 695 78.4 5.6e-14 CCDS82950.1 CAMK2D gene_id:817|Hs108|chr4 ( 498) 689 77.9 8.4e-14 CCDS43263.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 688 77.8 8.7e-14 CCDS3704.1 CAMK2D gene_id:817|Hs108|chr4 ( 478) 688 77.8 8.7e-14 CCDS3703.1 CAMK2D gene_id:817|Hs108|chr4 ( 499) 688 77.8 8.9e-14 CCDS42824.1 SPEG gene_id:10290|Hs108|chr2 (3267) 703 80.2 1.1e-13 CCDS10851.1 PSKH1 gene_id:5681|Hs108|chr16 ( 424) 679 76.9 1.4e-13 CCDS82948.1 CAMK2D gene_id:817|Hs108|chr4 ( 512) 675 76.6 2e-13 CCDS43386.1 CAMK2A gene_id:815|Hs108|chr5 ( 478) 674 76.5 2e-13 CCDS82949.1 CAMK2D gene_id:817|Hs108|chr4 ( 533) 675 76.7 2.1e-13 CCDS54797.1 CAMK2D gene_id:817|Hs108|chr4 ( 489) 673 76.4 2.2e-13 CCDS7336.1 CAMK2G gene_id:818|Hs108|chr10 ( 495) 672 76.4 2.4e-13 CCDS47127.1 CAMK2D gene_id:817|Hs108|chr4 ( 492) 667 75.9 3.2e-13 CCDS54421.1 TTN gene_id:7273|Hs108|chr2 (26926) 706 81.6 3.4e-13 CCDS54423.1 TTN gene_id:7273|Hs108|chr2 (27051) 706 81.6 3.4e-13 CCDS54422.1 TTN gene_id:7273|Hs108|chr2 (27118) 706 81.6 3.5e-13 CCDS54424.1 TTN gene_id:7273|Hs108|chr2 (33423) 706 81.7 3.9e-13 CCDS74610.1 TTN gene_id:7273|Hs108|chr2 (34350) 706 81.7 4e-13 CCDS59435.1 TTN gene_id:7273|Hs108|chr2 (35991) 706 81.8 4.1e-13 CCDS7338.1 CAMK2G gene_id:818|Hs108|chr10 ( 556) 663 75.6 4.4e-13 CCDS5488.1 CAMK2B gene_id:816|Hs108|chr7 ( 479) 661 75.4 4.6e-13 CCDS43387.1 CAMK2A gene_id:815|Hs108|chr5 ( 489) 659 75.2 5.2e-13 CCDS5484.1 CAMK2B gene_id:816|Hs108|chr7 ( 542) 658 75.2 5.9e-13 CCDS5483.1 CAMK2B gene_id:816|Hs108|chr7 ( 666) 658 75.3 6.7e-13 CCDS7337.1 CAMK2G gene_id:818|Hs108|chr10 ( 527) 654 74.8 7.4e-13 CCDS73153.1 CAMK2G gene_id:818|Hs108|chr10 ( 539) 654 74.8 7.5e-13 CCDS73561.1 DCLK1 gene_id:9201|Hs108|chr13 ( 422) 650 74.3 8.3e-13 CCDS55895.1 DCLK1 gene_id:9201|Hs108|chr13 ( 433) 650 74.3 8.4e-13 CCDS5487.1 CAMK2B gene_id:816|Hs108|chr7 ( 492) 651 74.5 8.6e-13 CCDS9354.1 DCLK1 gene_id:9201|Hs108|chr13 ( 729) 650 74.6 1.2e-12 >>CCDS43842.1 DAPK1 gene_id:1612|Hs108|chr9 (1430 aa) initn: 9549 init1: 9549 opt: 9549 Z-score: 4597.4 bits: 863.2 E(32554): 0 Smith-Waterman score: 9549; 99.9% identity (100.0% similar) in 1430 aa overlap (1-1430:1-1430) 10 20 30 40 50 60 pF1KB9 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 KQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 FSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 ARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 RHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEET 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNAC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLNAC 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 DKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 DKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCEAN 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 CNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 CNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAG 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 LLARLRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHSGSGKTTLVESLKCGLLRSFFRRRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LLARLRKDTHRGLFIQQLRPTQNLQPRIKLKLFGHSGSGKTTLVESLKCGLLRSFFRRRR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 PRLSSTNSSRFPPSPLASKPTVSVSINNLYPGCENVSVRSRSMMFEPGLTKGMLEVFVAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PRLSSTNSSRFPPSPLASKPTVSVSINNLYPGCENVSVRSRSMMFEPGLTKGMLEVFVAP 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 THHPHCSADDQSTKAIDIQNAYLNGVGDFSVWEFSGNPVYFCCYDYFAANDPTSIHVVVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 THHPHCSADDQSTKAIDIQNAYLNGVGDFSVWEFSGNPVYFCCYDYFAANDPTSIHVVVF 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 SLEEPYEIQLNQVIFWLSFLKSLVPVEEPIAFGGKLKNPLQVVLVATHADIMNVPRPAGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 SLEEPYEIQLNQVIFWLSFLKSLVPVEEPIAFGGKLKNPLQVVLVATHADIMNVPRPAGG 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 EFGYDKDTSLLKEIRNRFGNDLHISNKLFVLDAGASGSKDMKVLRNHLQEIRSQIVSVCP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 EFGYDKDTSLLKEIRNRFGNDLHISNKLFVLDAGASGSKDMKVLRNHLQEIRSQIVSVCP 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 PMTHLCEKIISTLPSWRKLNGPNQLMSLQQFVYDVQDQLNPLASEEDLRRIAQQLHSTGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PMTHLCEKIISTLPSWRKLNGPNQLMSLQQFVYDVQDQLNPLASEEDLRRIAQQLHSTGE 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 INIMQSETVQDVLLLDPRWLCTNVLGKLLSVETPRALHHYRGRYTVEDIQRLVPDSDVEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 INIMQSETVQDVLLLDPRWLCTNVLGKLLSVETPRALHHYRGRYTVEDIQRLVPDSDVEE 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 LLQILDAMDICARDLSSGTMVDVPALIKTDNLHRSWADEEDEVMVYGGVRIVPVEHLTPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LLQILDAMDICARDLSSGTMVDVPALIKTDNLHRSWADEEDEVMVYGGVRIVPVEHLTPF 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 PCGIFHKVQVNLCRWIHQQSTEGDADIRLWVNGCKLANRGAELLVLLVNHGQGIEVQVRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PCGIFHKVQVNLCRWIHQQSTEGDADIRLWVNGCKLANRGAELLVLLVNHGQGIEVQVRG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 LETEKIKCCLLLDSVCSTIENVMATTLPGLLTVKHYLSPQQLREHHEPVMIYQPRDFFRA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LETEKIKCCLLLDSVCSTIENVMATTLPGLLTVKHYLSPQQLREHHEPVMIYQPRDFFRA 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 QTLKETSLTNTMGGYKESFSSIMCFGCHDVYSQASLGMDIHASDLNLLTRRKLSRLLDPP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 QTLKETSLTNTMGGYKESFSSIMCFGCHDVYSQASLGMDIHASDLNLLTRRKLSRLLDPP 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 DPLGKDWCLLAMNLGLPDLVAKYNTNNGAPKDFLPSPLHALLREWTTYPESTVGTLMSKL :::::::::::::::::::::::::.:::::::::::::::::::::::::::::::::: CCDS43 DPLGKDWCLLAMNLGLPDLVAKYNTSNGAPKDFLPSPLHALLREWTTYPESTVGTLMSKL 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 pF1KB9 RELGRRDAADFLLKASSVFKINLDGNGQEAYASSCNSGTSYNSISSVVSR :::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 RELGRRDAADFLLKASSVFKINLDGNGQEAYASSCNSGTSYNSISSVVSR 1390 1400 1410 1420 1430 >>CCDS10188.1 DAPK2 gene_id:23604|Hs108|chr15 (370 aa) initn: 1604 init1: 1604 opt: 1656 Z-score: 825.6 bits: 163.4 E(32554): 1.1e-39 Smith-Waterman score: 1656; 68.7% identity (89.6% similar) in 355 aa overlap (1-350:11-362) 10 20 30 40 50 pF1KB9 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTK : :.:..:.:.:: ::::::::::.:::::::::::.:::::::::... CCDS10 MFQASMRSPNMEPFKQQKVEDFYDIGEELGSGQFAIVKKCREKSTGLEYAAKFIKKRQSR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 SSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKES .::::::::.::::::::... : ::::::.::::.:::.::::::.:::::::::.::: CCDS10 ASRRGVSREEIEREVSILRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKES 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 LTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDF :.::::: :.::::.:: :::. .:::::::::::::::.:.: :.::.:::::::.:. CCDS10 LSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIED 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 GNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVS : ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.. CCDS10 GVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANIT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 AVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASA ::.:.:..:.::.:: :::::::.::::. .::.:::..:.:::: : :.:::. :. :. CCDS10 AVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESV 250 260 270 280 290 300 300 310 320 330 340 pF1KB9 VNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTL-----DEEDSFVM ::.:.:.: .:..:: : ..:::..:.::.... .. : :. : : :.... CCDS10 VNLENFRKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHL---RPDEDLRNCESDTEEDIAR 310 320 330 340 350 350 360 370 380 390 400 pF1KB9 KAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRI . .: CCDS10 RKALHPRRRSSTS 360 370 >>CCDS12116.1 DAPK3 gene_id:1613|Hs108|chr19 (454 aa) initn: 1606 init1: 1543 opt: 1543 Z-score: 770.5 bits: 153.5 E(32554): 1.3e-36 Smith-Waterman score: 1543; 82.2% identity (97.1% similar) in 276 aa overlap (1-276:1-276) 10 20 30 40 50 60 pF1KB9 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSSRRGVSRED :..::::.:.:.:. ::::::::::.:.:::.:.:: .:::::::::: .:::::::::. CCDS12 MSTFRQEDVEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 IEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFL :::::.::.::.:::.::::...::::::.::::::.::::::::::::::::.:::.:: CCDS12 IEREVNILREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 KQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGT ::::.::.:::: .:::::::::::::::.:::.::::.::::.::::. :::::::::: CCDS12 KQILDGVHYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGT 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANVSAVNYEFEDEY :::::::::::::::::::::::::::::::::::::::.::::::.:.:::::.:..:: CCDS12 PEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 FSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFA ::::: :::::::::::::::.:::: .::.: ::: CCDS12 FSNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVRGEDSGRKPERRRLKTT 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL CCDS12 RLKEYTIKSHSSLPPNNSYADFERFSKVLEEAAAAEEGLRELQRSRRLCHEDVEALAAIY 310 320 330 340 350 360 >>CCDS43141.1 MYLK gene_id:4638|Hs108|chr3 (1845 aa) initn: 882 init1: 489 opt: 913 Z-score: 462.2 bits: 98.4 E(32554): 2e-19 Smith-Waterman score: 913; 41.5% identity (72.7% similar) in 366 aa overlap (1-355:1383-1734) 10 20 30 pF1KB9 MTVFRQENVDDYYDTGEELGSGQFAVVKKC .:. ...:.:.:: :.::::.:. : . CCDS43 TTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRL 1360 1370 1380 1390 1400 1410 40 50 60 70 80 90 pF1KB9 REKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVI ::.: .:.::.: .: .:.:..:.::.. ..::... ...:.:.... CCDS43 VEKKTRKVWAGKFFKAYSAKE------KENIRQEISIMNCLHHPKLVQCVDAFEEKANIV 1420 1430 1440 1450 1460 100 110 120 130 140 pF1KB9 LILELVAGGELFDFLAEKE-SLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLD ..::.:.:::::. . ... :::.: ....:: .:: :.:. :.:.:::::::: .. CCDS43 MVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVN 1470 1480 1490 1500 1510 1520 150 160 170 180 190 200 pF1KB9 RNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYI .. :::.::::::.... .. .: .::::::::::..::::.: .:::::::: :: CCDS43 KT--GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYI 1530 1540 1550 1560 1570 1580 210 220 230 240 250 260 pF1KB9 LLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDS :.:: :::.::. .::::::......:.:: :.. : ::::: :: :: :.:. . CCDS43 LVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQC 1590 1600 1610 1620 1630 1640 270 280 290 300 310 320 pF1KB9 LQHPWIKPKDTQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSR----SFLSR :::::. :::.. ..: : ...::. ::.::... . ::: : :: CCDS43 LQHPWLM-KDTKNMEAKKLSK---DRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSG 1650 1660 1670 1680 1690 1700 330 340 350 360 370 pF1KB9 SNMSVARSDDTLD------EEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHG . :.. . :. ::: : .:...:. .. CCDS43 RKSSTGSPTSPLNAEKLESEED--VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAAR 1710 1720 1730 1740 1750 380 390 400 410 420 430 pF1KB9 TPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLD CCDS43 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1760 1770 1780 1790 1800 1810 >>CCDS46896.1 MYLK gene_id:4638|Hs108|chr3 (1914 aa) initn: 882 init1: 489 opt: 913 Z-score: 462.1 bits: 98.5 E(32554): 2e-19 Smith-Waterman score: 913; 41.5% identity (72.7% similar) in 366 aa overlap (1-355:1452-1803) 10 20 30 pF1KB9 MTVFRQENVDDYYDTGEELGSGQFAVVKKC .:. ...:.:.:: :.::::.:. : . CCDS46 TTVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTINTEQKVSDFYDIEERLGSGKFGQVFRL 1430 1440 1450 1460 1470 1480 40 50 60 70 80 90 pF1KB9 REKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVI ::.: .:.::.: .: .:.:..:.::.. ..::... ...:.:.... CCDS46 VEKKTRKVWAGKFFKAYSAKE------KENIRQEISIMNCLHHPKLVQCVDAFEEKANIV 1490 1500 1510 1520 1530 100 110 120 130 140 pF1KB9 LILELVAGGELFDFLAEKE-SLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLD ..::.:.:::::. . ... :::.: ....:: .:: :.:. :.:.:::::::: .. CCDS46 MVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVN 1540 1550 1560 1570 1580 1590 150 160 170 180 190 200 pF1KB9 RNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYI .. :::.::::::.... .. .: .::::::::::..::::.: .:::::::: :: CCDS46 KT--GTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYI 1600 1610 1620 1630 1640 1650 210 220 230 240 250 260 pF1KB9 LLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDS :.:: :::.::. .::::::......:.:: :.. : ::::: :: :: :.:. . CCDS46 LVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQC 1660 1670 1680 1690 1700 1710 270 280 290 300 310 320 pF1KB9 LQHPWIKPKDTQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSR----SFLSR :::::. :::.. ..: : ...::. ::.::... . ::: : :: CCDS46 LQHPWLM-KDTKNMEAKKLSK---DRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSG 1720 1730 1740 1750 1760 330 340 350 360 370 pF1KB9 SNMSVARSDDTLD------EEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHG . :.. . :. ::: : .:...:. .. CCDS46 RKSSTGSPTSPLNAEKLESEED--VSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAAR 1770 1780 1790 1800 1810 1820 380 390 400 410 420 430 pF1KB9 TPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLD CCDS46 FDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNS 1830 1840 1850 1860 1870 1880 >>CCDS2315.1 STK17B gene_id:9262|Hs108|chr2 (372 aa) initn: 789 init1: 420 opt: 865 Z-score: 446.9 bits: 93.3 E(32554): 1.4e-18 Smith-Waterman score: 873; 42.5% identity (72.4% similar) in 369 aa overlap (5-367:24-370) 10 20 30 40 pF1KB9 MTVFRQENVDDYYD-TGEELGSGQFAVVKKCREKSTGLQYA ..:: ...: :..::: :.::::..: :::: .:: CCDS23 MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA 10 20 30 40 50 60 50 60 70 80 90 pF1KB9 AKFIKKRRTKSSRRGVS-REDIEREVSILKEIQH-PNVITLHEVYENKTDVILILELVAG :::.:::: :: . : .: .:...:. . : ::.::::::: ...::::: .:: CCDS23 AKFLKKRR-----RGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAG 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 GELFDF-LAE-KESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPR ::.:.. : : : ..:... ...::::.::::::. .:.:.::::.:: ::. : CCDS23 GEIFSLCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNI-LLSSIYPLGD 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 IKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASP :::.:::...:: . :...:.::::..::::.::.:. .:::.::.:.:.::. .:: CCDS23 IKIVDFGMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSP 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 FLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK :.:. .::: :.: :: .. .: ::..: :: :::. ::::.:.:: : . :.: :.. CCDS23 FVGEDNQETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQ 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 PKDTQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSD-D : .. . . .. .. . .::: : .. :.: : .. : : . CCDS23 QWDFENLFHPEETS---------SSSQTQDHSVR--SSEDKTSKS--SCNGTCGDREDKE 300 310 320 330 340 340 350 360 370 380 390 pF1KB9 TLDEEDSFVMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQIL .. :..:.: : . ::..:. ..:...: CCDS23 NIPEDSSMVSKRFRF---DDSLPNPHELVSDLLC 350 360 370 400 410 420 430 440 450 pF1KB9 QLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARY >>CCDS5470.1 STK17A gene_id:9263|Hs108|chr7 (414 aa) initn: 717 init1: 469 opt: 857 Z-score: 442.6 bits: 92.7 E(32554): 2.5e-18 Smith-Waterman score: 857; 45.2% identity (76.9% similar) in 294 aa overlap (3-291:49-337) 10 20 30 pF1KB9 MTVFRQENVDDYYDT--GEELGSGQFAVVKKC : : : .: :. :.::: :.::::.:: CCDS54 GSGRAGRGLSGPCRPPPPPQARGLLTEIRAVVRTEPFQDGYSLCPGRELGRGKFAVVRKC 20 30 40 50 60 70 40 50 60 70 80 pF1KB9 REKSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQ-HPNVITLHEVYENKTDV .:..: ..::::..::: .. : .: .:...:. : .: ::.::::::. ... CCDS54 IKKDSGKEFAAKFMRKRRKGQD----CRMEIIHEIAVLELAQDNPWVINLHEVYETASEM 80 90 100 110 120 130 90 100 110 120 130 140 pF1KB9 ILILELVAGGELFD-FLAEKE-SLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIML ::.:: .::::.:: .:..: .. :... ....:::.::..::. ...:.::::.::.: CCDS54 ILVLEYAAGGEIFDQCVADREEAFKEKDVQRLMRQILEGVHFLHTRDVVHLDLKPQNILL 140 150 160 170 180 190 150 160 170 180 190 200 pF1KB9 LDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVIT ... : :::.::::.. . ..:...:.::::.:::::..:.:... .:::::::.: CCDS54 TSES-PLGDIKIVDFGLSRILKNSEELREIMGTPEYVAPEILSYDPISMATDMWSIGVLT 200 210 220 230 240 250 210 220 230 240 250 260 pF1KB9 YILLSGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQ :..:.: :::::. ::::. :.: .: . .: :. : : :::: :::: :. : : . CCDS54 YVMLTGISPFLGNDKQETFLNISQMNLSYSEEEFDVLSESAVDFIRTLLVKKPEDRATAE 260 270 280 290 300 310 270 280 290 300 310 320 pF1KB9 DSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSN . :.:::. .. :. : .:. CCDS54 ECLKHPWLTQSSIQEPSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIVTEELIVV 320 330 340 350 360 370 >>CCDS34330.1 MYLK4 gene_id:340156|Hs108|chr6 (388 aa) initn: 696 init1: 435 opt: 823 Z-score: 426.6 bits: 89.6 E(32554): 1.9e-17 Smith-Waterman score: 823; 43.7% identity (77.5% similar) in 284 aa overlap (5-285:96-371) 10 20 30 pF1KB9 MTVFRQENVDDYYDTG--EELGSGQFAVVKKCRE .: :...: .. : ::.:.:. :.::.: CCDS34 RMPVKSKRTSALAVDIPAPPAPFDHRIVTAKQGAVNSFYTVSKTEILGGGRFGQVHKCEE 70 80 90 100 110 120 40 50 60 70 80 90 pF1KB9 KSTGLQYAAKFIKKRRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILI .:::. :::.:: : : ..:... :.:......: :.: :....:.:.:..:. CCDS34 TATGLKLAAKIIKTRGMK------DKEEVKNEISVMNQLDHANLIQLYDAFESKNDIVLV 130 140 150 160 170 100 110 120 130 140 150 pF1KB9 LELVAGGELFD-FLAEKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRN .: : :::::: .. :. .::: .. :.::: .:. ..:.. : :.:::::::. ..:. CCDS34 MEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRD 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB9 VPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILL . . :::::::::.. ...: ::::::.:::.:::. ... .::::.:::.:.:: CCDS34 AKQ--IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLL 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB9 SGASPFLGDTKQETLANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQ :: ::::::. ::: :. : ...::: :.. : ::.:: .::.:. . :.. ...:. CCDS34 SGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALK 300 310 320 330 340 350 280 290 300 310 320 330 pF1KB9 HPWIKPKDTQQALSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVA :::.. . .. :. CCDS34 HPWLSDHKLHSRLNAQKKKNRGSDAQDFVTK 360 370 380 >>CCDS76861.1 MYLK3 gene_id:91807|Hs108|chr16 (478 aa) initn: 694 init1: 417 opt: 817 Z-score: 422.8 bits: 89.2 E(32554): 3.2e-17 Smith-Waterman score: 817; 43.4% identity (72.5% similar) in 309 aa overlap (17-322:178-474) 10 20 30 40 pF1KB9 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKK : ::.:.:. :..: :::::: :::.:: CCDS76 DSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKV 150 160 170 180 190 200 50 60 70 80 90 100 pF1KB9 RRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLA . .:. :::.. :..:.....: :.: :....:.: . :..: : :::::: .. CCDS76 KSAKD------REDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT 210 220 230 240 250 260 110 120 130 140 150 160 pF1KB9 -EKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA :: ::: ... : .:: .::.:::. : :.:::::::. .... .::::::::: CCDS76 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQT--GHQIKIIDFGLA 270 280 290 300 310 170 180 190 200 210 220 pF1KB9 HKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET .. ...: ::::::.:::.:::: ... .::::.:::::.:::: :::::.: :: CCDS76 RRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAET 320 330 340 350 360 370 230 240 250 260 270 280 pF1KB9 LANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK--PKDTQQA . . ...:. . : . : ::::. :::::. . ::. . :.: :.. : .... CCDS76 MNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRS 380 390 400 410 420 430 290 300 310 320 330 340 pF1KB9 LSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSF .: : . .. :. :..:::. ... .:: :.: CCDS76 KTRLKSQLLLQ---KYIAQRKWKKHFYVVTAANRL-RKFPTSP 440 450 460 470 350 360 370 380 390 400 pF1KB9 VMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGS >>CCDS10723.2 MYLK3 gene_id:91807|Hs108|chr16 (819 aa) initn: 694 init1: 417 opt: 817 Z-score: 420.2 bits: 89.5 E(32554): 4.4e-17 Smith-Waterman score: 817; 43.4% identity (72.5% similar) in 309 aa overlap (17-322:519-815) 10 20 30 40 pF1KB9 MTVFRQENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKK : ::.:.:. :..: :::::: :::.:: CCDS10 DSPAPPAPFEHRVVSVKETSISAGYEVCQHEVLGGGRFGQVHRCTEKSTGLPLAAKIIKV 490 500 510 520 530 540 50 60 70 80 90 100 pF1KB9 RRTKSSRRGVSREDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLA . .:. :::.. :..:.....: :.: :....:.: . :..: : :::::: .. CCDS10 KSAKD------REDVKNEINIMNQLSHVNLIQLYDAFESKHSCTLVMEYVDGGELFDRIT 550 560 570 580 590 600 110 120 130 140 150 160 pF1KB9 -EKESLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLA :: ::: ... : .:: .::.:::. : :.:::::::. .... .::::::::: CCDS10 DEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVNQT--GHQIKIIDFGLA 610 620 630 640 650 660 170 180 190 200 210 220 pF1KB9 HKIDFGNEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQET .. ...: ::::::.:::.:::: ... .::::.:::::.:::: :::::.: :: CCDS10 RRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAET 670 680 690 700 710 720 230 240 250 260 270 280 pF1KB9 LANVSAVNYEFEDEYFSNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIK--PKDTQQA . . ...:. . : . : ::::. :::::. . ::. . :.: :.. : .... CCDS10 MNFIVNCSWDFDADTFEGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNNLPAKASRS 730 740 750 760 770 780 290 300 310 320 330 340 pF1KB9 LSRKASAVNMEKFKKFAARKKWKQSVRLISLCQRLSRSFLSRSNMSVARSDDTLDEEDSF .: : . .. :. :..:::. ... .:: :.: CCDS10 KTRLKSQLLLQ---KYIAQRKWKKHFYVVTAANRL-RKFPTSP 790 800 810 350 360 370 380 390 400 pF1KB9 VMKAIIHAINDDNVPGLQHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGS 1430 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:07:23 2016 done: Thu Nov 3 23:07:24 2016 Total Scan time: 4.980 Total Display time: 0.150 Function used was FASTA [36.3.4 Apr, 2011]