FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9268, 576 aa 1>>>pF1KB9268 576 - 576 aa - 576 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1940+/-0.000535; mu= 10.2702+/- 0.032 mean_var=216.9462+/-48.519, 0's: 0 Z-trim(113.3): 232 B-trim: 1062 in 3/53 Lambda= 0.087076 statistics sampled from 22266 (22540) to 22266 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.264), width: 16 Scan time: 10.780 The best scores are: opt bits E(85289) NP_775767 (OMIM: 610973) MAGUK p55 subfamily membe ( 576) 3774 488.2 3.2e-137 XP_011517639 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 576) 3774 488.2 3.2e-137 NP_001305099 (OMIM: 610973) MAGUK p55 subfamily me ( 576) 3774 488.2 3.2e-137 XP_016871231 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 574) 3749 485.0 2.8e-136 XP_016871230 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 657) 3431 445.1 3.2e-124 XP_011517640 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 451) 2958 385.5 2e-106 XP_005252426 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 318) 2083 275.4 1.9e-73 XP_016871232 (OMIM: 610973) PREDICTED: MAGUK p55 s ( 399) 1740 232.4 2.1e-60 XP_016880147 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 340) 1325 180.2 9.3e-45 NP_001923 (OMIM: 601114) MAGUK p55 subfamily membe ( 585) 1325 180.5 1.3e-44 XP_006721978 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 585) 1325 180.5 1.3e-44 NP_001317162 (OMIM: 601114) MAGUK p55 subfamily me ( 610) 1325 180.5 1.3e-44 XP_016880148 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 321) 1302 177.3 6.7e-44 XP_005268060 (OMIM: 606958) PREDICTED: MAGUK p55 s ( 641) 1227 168.3 7e-41 NP_001243479 (OMIM: 606958) MAGUK p55 subfamily me ( 641) 1227 168.3 7e-41 XP_011535389 (OMIM: 606958) PREDICTED: MAGUK p55 s ( 675) 1227 168.3 7.3e-41 XP_011535388 (OMIM: 606958) PREDICTED: MAGUK p55 s ( 675) 1227 168.3 7.3e-41 NP_071919 (OMIM: 606958) MAGUK p55 subfamily membe ( 675) 1227 168.3 7.3e-41 XP_016880149 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 299) 883 124.6 4.5e-28 XP_016880144 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 385) 883 124.8 5.2e-28 XP_006721979 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 387) 883 124.8 5.2e-28 XP_016880146 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 355) 820 116.8 1.2e-25 XP_016880145 (OMIM: 601114) PREDICTED: MAGUK p55 s ( 383) 820 116.8 1.3e-25 XP_016860109 (OMIM: 606575) PREDICTED: MAGUK p55 s ( 606) 780 112.1 5.5e-24 NP_149055 (OMIM: 606575) MAGUK p55 subfamily membe ( 637) 780 112.1 5.6e-24 NP_001265303 (OMIM: 600723) MAGUK p55 subfamily me ( 413) 643 94.7 6.5e-19 NP_001265304 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 643 94.8 7.7e-19 NP_001265302 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 643 94.8 7.7e-19 NP_001265300 (OMIM: 600723) MAGUK p55 subfamily me ( 541) 643 94.8 7.7e-19 NP_005365 (OMIM: 600723) MAGUK p55 subfamily membe ( 552) 643 94.8 7.8e-19 NP_001265310 (OMIM: 600723) MAGUK p55 subfamily me ( 552) 643 94.8 7.8e-19 NP_001265305 (OMIM: 600723) MAGUK p55 subfamily me ( 569) 643 94.8 8e-19 NP_001265301 (OMIM: 600723) MAGUK p55 subfamily me ( 576) 643 94.8 8e-19 NP_001265299 (OMIM: 600723) MAGUK p55 subfamily me ( 597) 643 94.9 8.2e-19 XP_011523129 (OMIM: 600723) PREDICTED: MAGUK p55 s ( 630) 643 94.9 8.5e-19 XP_005249832 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 428) 615 91.2 7.6e-18 XP_006715802 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 615 91.3 8.8e-18 XP_006715801 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 615 91.3 8.8e-18 XP_016867805 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 615 91.3 8.8e-18 NP_001289966 (OMIM: 606959) MAGUK p55 subfamily me ( 540) 615 91.3 8.8e-18 XP_006715803 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 615 91.3 8.8e-18 XP_016867806 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 615 91.3 8.8e-18 XP_016867804 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 615 91.3 8.8e-18 XP_011513727 (OMIM: 606959) PREDICTED: MAGUK p55 s ( 540) 615 91.3 8.8e-18 NP_057531 (OMIM: 606959) MAGUK p55 subfamily membe ( 540) 615 91.3 8.8e-18 XP_016884811 (OMIM: 300189,300850) PREDICTED: disk ( 498) 602 89.6 2.6e-17 XP_011529185 (OMIM: 300189,300850) PREDICTED: disk ( 835) 602 89.9 3.6e-17 XP_016884812 (OMIM: 300189,300850) PREDICTED: disk ( 494) 584 87.3 1.2e-16 NP_001119527 (OMIM: 300172,300422,300749) peripher ( 897) 588 88.2 1.3e-16 XP_011542297 (OMIM: 300172,300422,300749) PREDICTE ( 903) 588 88.2 1.3e-16 >>NP_775767 (OMIM: 610973) MAGUK p55 subfamily member 7 (576 aa) initn: 3774 init1: 3774 opt: 3774 Z-score: 2584.6 bits: 488.2 E(85289): 3.2e-137 Smith-Waterman score: 3774; 99.8% identity (100.0% similar) in 576 aa overlap (1-576:1-576) 10 20 30 40 50 60 pF1KB9 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RRPEILVQPLKVSNRKSSGFRRSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: NP_775 RRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_775 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD 490 500 510 520 530 540 550 560 570 pF1KB9 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS :::::::::::::::::::::::::::::::::::: NP_775 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS 550 560 570 >>XP_011517639 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (576 aa) initn: 3774 init1: 3774 opt: 3774 Z-score: 2584.6 bits: 488.2 E(85289): 3.2e-137 Smith-Waterman score: 3774; 99.8% identity (100.0% similar) in 576 aa overlap (1-576:1-576) 10 20 30 40 50 60 pF1KB9 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RRPEILVQPLKVSNRKSSGFRRSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: XP_011 RRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD 490 500 510 520 530 540 550 560 570 pF1KB9 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS :::::::::::::::::::::::::::::::::::: XP_011 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS 550 560 570 >>NP_001305099 (OMIM: 610973) MAGUK p55 subfamily member (576 aa) initn: 3774 init1: 3774 opt: 3774 Z-score: 2584.6 bits: 488.2 E(85289): 3.2e-137 Smith-Waterman score: 3774; 99.8% identity (100.0% similar) in 576 aa overlap (1-576:1-576) 10 20 30 40 50 60 pF1KB9 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RRPEILVQPLKVSNRKSSGFRRSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: NP_001 RRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD 490 500 510 520 530 540 550 560 570 pF1KB9 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS :::::::::::::::::::::::::::::::::::: NP_001 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS 550 560 570 >>XP_016871231 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (574 aa) initn: 3431 init1: 3431 opt: 3749 Z-score: 2567.7 bits: 485.0 E(85289): 2.8e-136 Smith-Waterman score: 3749; 99.5% identity (99.7% similar) in 576 aa overlap (1-576:1-574) 10 20 30 40 50 60 pF1KB9 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY :::::::::::::::::::::::::::::::::::::::::::::::::: :::::::: XP_016 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSL--IHEKLHYY 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB9 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB9 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 RRPEILVQPLKVSNRKSSGFRRSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: XP_016 RRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD 480 490 500 510 520 530 550 560 570 pF1KB9 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS :::::::::::::::::::::::::::::::::::: XP_016 KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS 540 550 560 570 >>XP_016871230 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (657 aa) initn: 3431 init1: 3431 opt: 3431 Z-score: 2351.1 bits: 445.1 E(85289): 3.2e-124 Smith-Waterman score: 3431; 99.8% identity (100.0% similar) in 524 aa overlap (53-576:134-657) 30 40 50 60 70 80 pF1KB9 AQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYYEKQSPVPILHGAAALADDLAEE :::::::::::::::::::::::::::::: XP_016 EGRVSGERWADLFLHLASCQLCQRDLGVTLIHEKLHYYEKQSPVPILHGAAALADDLAEE 110 120 130 140 150 160 90 100 110 120 130 140 pF1KB9 LQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEEDSVKIIRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEEDSVKIIRL 170 180 190 200 210 220 150 160 170 180 190 200 pF1KB9 VKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEII 230 240 250 260 270 280 210 220 230 240 250 260 pF1KB9 QILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDIL 290 300 310 320 330 340 270 280 290 300 310 320 pF1KB9 QIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_016 QIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFRK 350 360 370 380 390 400 330 340 350 360 370 380 pF1KB9 SFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLN 410 420 430 440 450 460 390 400 410 420 430 440 pF1KB9 ELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKN 470 480 490 500 510 520 450 460 470 480 490 500 pF1KB9 NYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAK 530 540 550 560 570 580 510 520 530 540 550 560 pF1KB9 IISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKL 590 600 610 620 630 640 570 pF1KB9 ETETHWVPVSWLHS :::::::::::::: XP_016 ETETHWVPVSWLHS 650 >>XP_011517640 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (451 aa) initn: 2958 init1: 2958 opt: 2958 Z-score: 2031.8 bits: 385.5 E(85289): 2e-106 Smith-Waterman score: 2958; 99.8% identity (100.0% similar) in 451 aa overlap (126-576:1-451) 100 110 120 130 140 150 pF1KB9 LKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKK :::::::::::::::::::::::::::::: XP_011 MPEDIDDEEDSVKIIRLVKNREPLGATIKK 10 20 30 160 170 180 190 200 210 pF1KB9 DEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAITFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAITFK 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB9 IIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQA 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB9 KHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFRRSFRLSRKDKKTNK ::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::: XP_011 KHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNK 160 170 180 190 200 210 340 350 360 370 380 390 pF1KB9 SMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQH 220 230 240 250 260 270 400 410 420 430 440 450 pF1KB9 YGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSV 280 290 300 310 320 330 460 470 480 490 500 510 pF1KB9 LAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKP 340 350 360 370 380 390 520 530 540 550 560 570 pF1KB9 FTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWVPVSWLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWVPVSWLH 400 410 420 430 440 450 pF1KB9 S : XP_011 S >>XP_005252426 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (318 aa) initn: 2083 init1: 2083 opt: 2083 Z-score: 1439.5 bits: 275.4 E(85289): 1.9e-73 Smith-Waterman score: 2083; 100.0% identity (100.0% similar) in 318 aa overlap (1-318:1-318) 10 20 30 40 50 60 pF1KB9 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 RRPEILVQPLKVSNRKSSGFRRSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY :::::::::::::::::: XP_005 RRPEILVQPLKVSNRKSS 310 >>XP_016871232 (OMIM: 610973) PREDICTED: MAGUK p55 subfa (399 aa) initn: 1764 init1: 1740 opt: 1740 Z-score: 1205.5 bits: 232.4 E(85289): 2.1e-60 Smith-Waterman score: 1740; 100.0% identity (100.0% similar) in 266 aa overlap (53-318:134-399) 30 40 50 60 70 80 pF1KB9 AQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYYEKQSPVPILHGAAALADDLAEE :::::::::::::::::::::::::::::: XP_016 EGRVSGERWADLFLHLASCQLCQRDLGVTLIHEKLHYYEKQSPVPILHGAAALADDLAEE 110 120 130 140 150 160 90 100 110 120 130 140 pF1KB9 LQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEEDSVKIIRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEEDSVKIIRL 170 180 190 200 210 220 150 160 170 180 190 200 pF1KB9 VKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEII :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEII 230 240 250 260 270 280 210 220 230 240 250 260 pF1KB9 QILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDIL 290 300 310 320 330 340 270 280 290 300 310 320 pF1KB9 QIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSS 350 360 370 380 390 330 340 350 360 370 380 pF1KB9 SFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLN >>XP_016880147 (OMIM: 601114) PREDICTED: MAGUK p55 subfa (340 aa) initn: 853 init1: 829 opt: 1325 Z-score: 924.5 bits: 180.2 E(85289): 9.3e-45 Smith-Waterman score: 1325; 64.8% identity (86.8% similar) in 304 aa overlap (1-302:26-325) 10 20 30 pF1KB9 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDL ::.:: :.::.: :: : .::.: . .:.. XP_016 MELQYPPPPPSPRICRERSGGDNASMPVLS----EDSGLHETLALLTSQLRPDSNHKEEM 10 20 30 40 50 40 50 60 70 80 90 pF1KB9 TFLWDMFGEKSLHSLVKIHEKLHYYEKQSPVPILHGAAALADDLAEELQNKPLNSEIREL :: :.:.:::: :.::::::.:::.:::.:.::.:.:::.:. :::: ..:. ::: XP_016 GFLRDVFSEKSLSYLMKIHEKLRYYERQSPTPVLHSAVALAEDVMEELQAASVHSDEREL 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 LKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDE--EDSVKIIRLVKNREPLGATI :.::: :...:.: :::::::::.::::::.:..::.. :.::::.:::::.::::::: XP_016 LQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEESVKIVRLVKNKEPLGATI 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 KKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAIT ..::..::..:::::::::::::::.:::::::::::: : :::.:: ::::::::.:: XP_016 RRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSIT 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 FKIIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWW .::::...:: ::.:.:..::: ::: ::.::::.:::: :.. ..:...:::: ::: XP_016 LKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWW 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB9 QAKHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFRRSFRLSRKDKKT :::. .:.: :::::::: ::::::. :: XP_016 QAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPP 300 310 320 330 340 >>NP_001923 (OMIM: 601114) MAGUK p55 subfamily member 3 (585 aa) initn: 2093 init1: 829 opt: 1325 Z-score: 921.9 bits: 180.5 E(85289): 1.3e-44 Smith-Waterman score: 2098; 54.1% identity (80.6% similar) in 597 aa overlap (1-574:1-584) 10 20 30 40 50 60 pF1KB9 MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY ::.:: :.::.: :: : .::.: . .:.. :: :.:.:::: :.::::::.:: NP_001 MPVLSE----DSGLHETLALLTSQLRPDSNHKEEMGFLRDVFSEKSLSYLMKIHEKLRYY 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD :.:::.:.::.:.:::.:. :::: ..:. ::::.::: :...:.: :::::::::.: NP_001 ERQSPTPVLHSAVALAEDVMEELQAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFD 60 70 80 90 100 110 130 140 150 160 170 pF1KB9 PVLPPMPEDIDDE--EDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGL :::::.:..::.. :.::::.:::::.:::::::..::..::..::::::::::::::: NP_001 PVLPPLPDNIDEDFDEESVKIVRLVKNKEPLGATIRRDEHSGAVVVARIMRGGAADRSGL 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IHVGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFD .:::::::::::: : :::.:: ::::::::.::.::::...:: ::.:.:..::: NP_001 VHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFH 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB9 YNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRL ::: ::.::::.:::: :.. ..:...:::: ::::::. .:.: :::::::: :::::: NP_001 YNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRL 240 250 260 270 280 290 300 310 320 330 pF1KB9 ALRR-------PEILVQPL--KVSNRKS------------SGFRRSFRLSRKDKKTNKSM . :: :. : .: . .... .:.::::::. ... ... NP_001 SYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQ- 300 310 320 330 340 350 340 350 360 370 380 390 pF1KB9 YECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYG : : :. .. .. :::::. :..: .:. :::::.: .:. :.:::.:.. . ::.: NP_001 -EGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFG 360 370 380 390 400 410 400 410 420 430 440 450 pF1KB9 VTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLA :.:::::: :.:.:..:::: :.::. ::.:...:::.:.::::.: ::::......:.: NP_001 VAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMA 420 430 440 450 460 470 460 470 480 490 500 510 pF1KB9 KNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFT ::::::.::.:...:.::: :::::.::.:: ..: ::. . . .: .: :: NP_001 KNKVCLVDVEPEALKQLRTSEFKPYIIFVKPA----IQEKRKTPPMSPACED--TAAPFD 480 490 500 510 520 520 530 540 550 560 570 pF1KB9 EEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS :.. ::: :: ... .:::: : .....:: :...::....:: .::::::::. NP_001 EQQ-QEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR 530 540 550 560 570 580 576 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 21:15:19 2016 done: Sat Nov 5 21:15:21 2016 Total Scan time: 10.780 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]