FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9279, 311 aa
1>>>pF1KB9279 311 - 311 aa - 311 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9067+/-0.000422; mu= 17.4273+/- 0.026
mean_var=66.8676+/-13.513, 0's: 0 Z-trim(110.1): 234 B-trim: 750 in 1/50
Lambda= 0.156843
statistics sampled from 18143 (18408) to 18143 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.58), E-opt: 0.2 (0.216), width: 16
Scan time: 6.930
The best scores are: opt bits E(85289)
NP_001098117 (OMIM: 616149) solute carrier family ( 311) 1998 461.4 1.1e-129
NP_060625 (OMIM: 616149) solute carrier family 25 ( 310) 1980 457.3 1.8e-128
NP_115691 (OMIM: 610816) solute carrier family 25 ( 321) 1240 289.9 4.6e-78
XP_005247632 (OMIM: 616149) PREDICTED: solute carr ( 204) 1162 272.1 6.7e-73
XP_011540598 (OMIM: 610816) PREDICTED: solute carr ( 258) 1016 239.1 7.1e-63
XP_005263560 (OMIM: 610816) PREDICTED: solute carr ( 254) 986 232.3 7.8e-61
NP_110407 (OMIM: 610815,616839) mitochondrial fola ( 315) 416 103.4 6.1e-22
XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 346 87.5 3.2e-17
NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 346 87.5 3.2e-17
XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 346 87.5 3.2e-17
XP_006716415 (OMIM: 610387) PREDICTED: mitoferrin- ( 266) 346 87.5 3.2e-17
NP_001304743 (OMIM: 610387) mitoferrin-1 isoform 3 ( 266) 346 87.5 3.2e-17
XP_011542852 (OMIM: 610387) PREDICTED: mitoferrin- ( 272) 346 87.5 3.2e-17
NP_057696 (OMIM: 610387) mitoferrin-1 isoform 1 [H ( 338) 346 87.6 3.8e-17
XP_011538513 (OMIM: 139080) PREDICTED: graves dise ( 332) 305 78.3 2.3e-14
NP_689920 (OMIM: 139080) graves disease carrier pr ( 332) 305 78.3 2.3e-14
XP_016869366 (OMIM: 610815,616839) PREDICTED: mito ( 183) 296 76.1 6e-14
NP_077008 (OMIM: 608746) calcium-binding mitochond ( 468) 296 76.4 1.2e-13
XP_011526583 (OMIM: 608746) PREDICTED: calcium-bin ( 515) 296 76.4 1.3e-13
XP_011526580 (OMIM: 608746) PREDICTED: calcium-bin ( 549) 296 76.5 1.4e-13
XP_011526579 (OMIM: 608746) PREDICTED: calcium-bin ( 560) 296 76.5 1.4e-13
XP_016882774 (OMIM: 608746) PREDICTED: calcium-bin ( 562) 296 76.5 1.4e-13
XP_011526577 (OMIM: 608746) PREDICTED: calcium-bin ( 577) 296 76.5 1.5e-13
XP_011526576 (OMIM: 608746) PREDICTED: calcium-bin ( 624) 296 76.5 1.5e-13
XP_005251746 (OMIM: 608745) PREDICTED: calcium-bin ( 366) 293 75.6 1.6e-13
XP_006717012 (OMIM: 608745) PREDICTED: calcium-bin ( 378) 293 75.7 1.7e-13
NP_443133 (OMIM: 608745) calcium-binding mitochond ( 469) 293 75.7 2e-13
XP_006717011 (OMIM: 608745) PREDICTED: calcium-bin ( 481) 293 75.7 2e-13
NP_001006643 (OMIM: 608745) calcium-binding mitoch ( 489) 293 75.7 2.1e-13
NP_001252543 (OMIM: 608745) calcium-binding mitoch ( 501) 293 75.7 2.1e-13
NP_001006642 (OMIM: 608745) calcium-binding mitoch ( 503) 293 75.7 2.1e-13
NP_001317917 (OMIM: 608745) calcium-binding mitoch ( 515) 293 75.8 2.1e-13
XP_016856593 (OMIM: 608744) PREDICTED: calcium-bin ( 271) 289 74.6 2.4e-13
NP_998816 (OMIM: 608744) calcium-binding mitochond ( 458) 289 74.8 3.7e-13
NP_037518 (OMIM: 608744) calcium-binding mitochond ( 477) 289 74.8 3.8e-13
XP_016864579 (OMIM: 616150) PREDICTED: solute carr ( 257) 282 73.0 7e-13
XP_016864576 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13
XP_006714609 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13
XP_016864575 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13
XP_016864577 (OMIM: 616150) PREDICTED: solute carr ( 311) 282 73.1 8.1e-13
XP_011535589 (OMIM: 607571) PREDICTED: mitochondri ( 303) 272 70.8 3.8e-12
NP_112581 (OMIM: 610796) ADP/ATP translocase 4 iso ( 315) 270 70.4 5.4e-12
XP_011535590 (OMIM: 607571) PREDICTED: mitochondri ( 269) 267 69.7 7.7e-12
NP_001164641 (OMIM: 607571) mitochondrial 2-oxodic ( 298) 267 69.7 8.3e-12
NP_085134 (OMIM: 607571) mitochondrial 2-oxodicarb ( 299) 267 69.7 8.3e-12
NP_001311243 (OMIM: 139080) graves disease carrier ( 234) 257 67.3 3.3e-11
NP_001311244 (OMIM: 139080) graves disease carrier ( 234) 257 67.3 3.3e-11
XP_011535591 (OMIM: 607571) PREDICTED: mitochondri ( 267) 257 67.4 3.7e-11
XP_016873060 (OMIM: 610825) PREDICTED: solute carr ( 184) 254 66.6 4.4e-11
XP_016873059 (OMIM: 610825) PREDICTED: solute carr ( 184) 254 66.6 4.4e-11
>>NP_001098117 (OMIM: 616149) solute carrier family 25 m (311 aa)
initn: 1998 init1: 1998 opt: 1998 Z-score: 2449.6 bits: 461.4 E(85289): 1.1e-129
Smith-Waterman score: 1998; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311)
10 20 30 40 50 60
pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 TTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA
250 260 270 280 290 300
310
pF1KB9 TYELVVYLLNG
:::::::::::
NP_001 TYELVVYLLNG
310
>>NP_060625 (OMIM: 616149) solute carrier family 25 memb (310 aa)
initn: 1656 init1: 1601 opt: 1980 Z-score: 2427.6 bits: 457.3 E(85289): 1.8e-128
Smith-Waterman score: 1980; 99.7% identity (99.7% similar) in 311 aa overlap (1-311:1-310)
10 20 30 40 50 60
pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 HMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 TTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TTIAYPH-VVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMA
250 260 270 280 290
310
pF1KB9 TYELVVYLLNG
:::::::::::
NP_060 TYELVVYLLNG
300 310
>>NP_115691 (OMIM: 610816) solute carrier family 25 memb (321 aa)
initn: 876 init1: 640 opt: 1240 Z-score: 1522.4 bits: 289.9 E(85289): 4.6e-78
Smith-Waterman score: 1240; 60.3% identity (84.3% similar) in 312 aa overlap (3-309:8-316)
10 20 30 40 50
pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSV---TLYISEVQLNTMA
...::.::::::::::::::.::::::.::::::: . :.: .:.:.:..
NP_115 MATGGQQKENTLLHLFAGGCGGTVGAIFTCPLEVIKTRLQSSRLALRTVYYPQVHLGTIS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 GASVNR--VVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLN
::.. : :.:: .. :: :::::::.::::::::::::::::::.::: ::. ::..:
NP_115 GAGMVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLVGVAPSRAVYFACYSKAKEQFN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 DVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQT
.: :.:. ::..::. :.: . . ::::..:::.::. . :: ..:....:.: ::::
NP_115 GIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQMNTLQCARYVYQT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 DGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMM
.:..:::::..:::::::::.: :.::::.:. : : ::. .. : :....: :.:
NP_115 EGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTE---KNSTSFFGLM
190 200 210 220 230
240 250 260 270 280 290
pF1KB9 LAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVR
::: :: ::. :::::::.:::::::::::.:: :: :. .:::: ..:::: ..:.:
NP_115 AAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYLAFYRGLFAQLIR
240 250 260 270 280 290
300 310
pF1KB9 QIPNTAIMMATYELVVYLLNG
:::::::...::::.::::
NP_115 QIPNTAIVLSTYELIVYLLEDRTQ
300 310 320
>>XP_005247632 (OMIM: 616149) PREDICTED: solute carrier (204 aa)
initn: 1162 init1: 1162 opt: 1162 Z-score: 1429.7 bits: 272.1 E(85289): 6.7e-73
Smith-Waterman score: 1162; 100.0% identity (100.0% similar) in 183 aa overlap (129-311:22-204)
100 110 120 130 140 150
pF1KB9 FAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRM
::::::::::::::::::::::::::::::
XP_005 MGFFPASNSFVTWKSIMDRSLGFTAITATNPIWLIKTRLQLDARNRGERRM
10 20 30 40 50
160 170 180 190 200 210
pF1KB9 GAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEE
60 70 80 90 100 110
220 230 240 250 260 270
pF1KB9 SVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYG
120 130 140 150 160 170
280 290 300 310
pF1KB9 SLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
:::::::::::::::::::::::::::::::::
XP_005 SLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
180 190 200
>>XP_011540598 (OMIM: 610816) PREDICTED: solute carrier (258 aa)
initn: 650 init1: 631 opt: 1016 Z-score: 1249.8 bits: 239.1 E(85289): 7.1e-63
Smith-Waterman score: 1016; 60.4% identity (84.4% similar) in 250 aa overlap (60-309:7-253)
30 40 50 60 70 80
pF1KB9 VKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLV
:.:: .. :: :::::::.:::::::::::
XP_011 MVRPTSVTPGLFQVLKSILEKEGPKSLFRGLGPNLV
10 20 30
90 100 110 120 130 140
pF1KB9 GVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLD
:::::::.::: ::. ::..: .: :.:. ::..::. :.: . . ::::..:::.::.
XP_011 GVAPSRAVYFACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB9 ARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKT
. :: ..:....:.: ::::.:..:::::..:::::::::.: :.::::.:. : :
XP_011 QKVRGSKQMNTLQCARYVYQTEGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPL
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB9 ASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLS
::. .. : :....: :.: ::: :: ::. :::::::.:::::::::::.:: ::
XP_011 ASSANGTE---KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTAR
160 170 180 190 200 210
270 280 290 300 310
pF1KB9 LLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
:. .:::: ..:::: ..:.::::::::...::::.::::
XP_011 LVFREEGYLAFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ
220 230 240 250
>>XP_005263560 (OMIM: 610816) PREDICTED: solute carrier (254 aa)
initn: 607 init1: 607 opt: 986 Z-score: 1213.2 bits: 232.3 E(85289): 7.8e-61
Smith-Waterman score: 986; 60.6% identity (84.6% similar) in 241 aa overlap (69-309:12-249)
40 50 60 70 80 90
pF1KB9 VTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIY
. :::::::.::::::::::::::::::.:
XP_005 MQCFGHKETEDRSILEKEGPKSLFRGLGPNLVGVAPSRAVY
10 20 30 40
100 110 120 130 140 150
pF1KB9 FAAYSNCKEKLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRM
:: ::. ::..: .: :.:. ::..::. :.: . . ::::..:::.::. . :: ..:
XP_005 FACYSKAKEQFNGIFVPNSNIVHIFSAGSAAFITNSLMNPIWMVKTRMQLEQKVRGSKQM
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB9 GAFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEE
....:.: ::::.:..:::::..:::::::::.: :.::::.:. : : ::. .. :
XP_005 NTLQCARYVYQTEGIRGFYRGLTASYAGISETIICFAIYESLKKYLKEAPLASSANGTE-
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 SVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYG
:....: :.: ::: :: ::. :::::::.:::::::::::.:: :: :. .::::
XP_005 --KNSTSFFGLMAAAALSKGCASCIAYPHEVIRTRLREEGTKYKSFVQTARLVFREEGYL
170 180 190 200 210
280 290 300 310
pF1KB9 SLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
..:::: ..:.::::::::...::::.::::
XP_005 AFYRGLFAQLIRQIPNTAIVLSTYELIVYLLEDRTQ
220 230 240 250
>>NP_110407 (OMIM: 610815,616839) mitochondrial folate t (315 aa)
initn: 434 init1: 162 opt: 416 Z-score: 514.9 bits: 103.4 E(85289): 6.1e-22
Smith-Waterman score: 433; 30.1% identity (60.5% similar) in 306 aa overlap (9-309:25-307)
10 20 30 40
pF1KB9 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYIS
.:.:: ::... . ::..:: :. :.
NP_110 MTGQGQSASGSSAWSTVFRHVRYENLIAGVSGGVLSNLALHPLDLVKIRFAVSD------
10 20 30 40 50
50 60 70 80 90 100
pF1KB9 EVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSN
: . : : :::: .: . .: :.:..:. ::. :.. : ..:: :.
NP_110 --------GLEL-RPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNA
60 70 80 90 100
110 120 130 140 150
pF1KB9 CKE-KLNDVFDPDSTQVHMISAAMAGFTAITATNPIWLIKTRL--QLDARNRGERRM--G
: : . . . ...::: :: .. :::.:. :::: : :: . .:. :
NP_110 IKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKG
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB9 AFECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEES
:. . :.:. .:..:.:.:. . : :. ...:. :: ::. : . .. :.
NP_110 MFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYE-----LLKLKYNQHINRLPEA
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB9 VKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGYGS
. ..... :: :: :.. .::..:::.::... : . ..... ..:: :.
NP_110 QLSTVEYISV---AALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGG
230 240 250 260 270
280 290 300 310
pF1KB9 LYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
.:.:.. .:.: : : ...:: : ..:
NP_110 FYKGIAPNLIRVTPACCITFVVYENVSHFLLDLREKRK
280 290 300 310
>>XP_011542855 (OMIM: 610387) PREDICTED: mitoferrin-1 is (266 aa)
initn: 295 init1: 128 opt: 346 Z-score: 430.3 bits: 87.5 E(85289): 3.2e-17
Smith-Waterman score: 346; 29.6% identity (64.0% similar) in 247 aa overlap (68-309:19-255)
40 50 60 70 80 90
pF1KB9 SVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAI
:: :.. :: .::.. ..:..:..:.
XP_011 MQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM
10 20 30 40
100 110 120 130 140 150
pF1KB9 YFAAYSNCKEKLNDVF--DPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGE
::: : : :. ::::: . .: .. :...:: . .. :: ..: :::. : .
XP_011 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM--YNSQH
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB9 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME
: .:. :.: :..:.:: .:::..... . .: :::. :: ..... ..:
XP_011 R--SAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTY----
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 NDEESVKEASDFVGMMLAAATSK--TCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLV
. .: .. ..: . ::::. .: : . .: : : . . . .. ... .
XP_011 -NPQSHIISGGLAGALAAAATTPLDVCKTLLN-TQENVALSLANISGRLSGMANAFRTVY
170 180 190 200 210
280 290 300 310
pF1KB9 QEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
: .: .. ..:. .... :.:.::: ..::. :.:
XP_011 QLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY
220 230 240 250 260
>>NP_001304742 (OMIM: 610387) mitoferrin-1 isoform 3 [Ho (266 aa)
initn: 295 init1: 128 opt: 346 Z-score: 430.3 bits: 87.5 E(85289): 3.2e-17
Smith-Waterman score: 346; 29.6% identity (64.0% similar) in 247 aa overlap (68-309:19-255)
40 50 60 70 80 90
pF1KB9 SVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAI
:: :.. :: .::.. ..:..:..:.
NP_001 MQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM
10 20 30 40
100 110 120 130 140 150
pF1KB9 YFAAYSNCKEKLNDVF--DPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGE
::: : : :. ::::: . .: .. :...:: . .. :: ..: :::. : .
NP_001 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM--YNSQH
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB9 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME
: .:. :.: :..:.:: .:::..... . .: :::. :: ..... ..:
NP_001 R--SAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTY----
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 NDEESVKEASDFVGMMLAAATSK--TCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLV
. .: .. ..: . ::::. .: : . .: : : . . . .. ... .
NP_001 -NPQSHIISGGLAGALAAAATTPLDVCKTLLN-TQENVALSLANISGRLSGMANAFRTVY
170 180 190 200 210
280 290 300 310
pF1KB9 QEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
: .: .. ..:. .... :.:.::: ..::. :.:
NP_001 QLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY
220 230 240 250 260
>>XP_016869021 (OMIM: 610387) PREDICTED: mitoferrin-1 is (266 aa)
initn: 295 init1: 128 opt: 346 Z-score: 430.3 bits: 87.5 E(85289): 3.2e-17
Smith-Waterman score: 346; 29.6% identity (64.0% similar) in 247 aa overlap (68-309:19-255)
40 50 60 70 80 90
pF1KB9 SVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAI
:: :.. :: .::.. ..:..:..:.
XP_016 MQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAM
10 20 30 40
100 110 120 130 140 150
pF1KB9 YFAAYSNCKEKLNDVF--DPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGE
::: : : :. ::::: . .: .. :...:: . .. :: ..: :::. : .
XP_016 YFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQM--YNSQH
50 60 70 80 90 100
160 170 180 190 200 210
pF1KB9 RRMGAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTME
: .:. :.: :..:.:: .:::..... . .: :::. :: ..... ..:
XP_016 R--SAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNPHRTY----
110 120 130 140 150 160
220 230 240 250 260 270
pF1KB9 NDEESVKEASDFVGMMLAAATSK--TCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLV
. .: .. ..: . ::::. .: : . .: : : . . . .. ... .
XP_016 -NPQSHIISGGLAGALAAAATTPLDVCKTLLN-TQENVALSLANISGRLSGMANAFRTVY
170 180 190 200 210
280 290 300 310
pF1KB9 QEEGYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG
: .: .. ..:. .... :.:.::: ..::. :.:
XP_016 QLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFLTKRQLENRAPY
220 230 240 250 260
311 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:15:24 2016 done: Sat Nov 5 13:15:25 2016
Total Scan time: 6.930 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]