FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9284, 195 aa 1>>>pF1KB9284 195 - 195 aa - 195 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.5989+/-0.000387; mu= -9.2903+/- 0.024 mean_var=355.0660+/-74.735, 0's: 0 Z-trim(123.0): 20 B-trim: 0 in 0/58 Lambda= 0.068064 statistics sampled from 41987 (42010) to 41987 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.493), width: 16 Scan time: 6.320 The best scores are: opt bits E(85289) XP_016872904 (OMIM: 616316) PREDICTED: protein FAM ( 193) 923 103.1 2.9e-22 NP_055974 (OMIM: 616316) protein FAM168A isoform 2 ( 235) 731 84.3 1.6e-16 NP_001272979 (OMIM: 616316) protein FAM168A isofor ( 244) 724 83.7 2.6e-16 >>XP_016872904 (OMIM: 616316) PREDICTED: protein FAM168A (193 aa) initn: 1017 init1: 510 opt: 923 Z-score: 520.7 bits: 103.1 E(85289): 2.9e-22 Smith-Waterman score: 923; 66.2% identity (85.6% similar) in 195 aa overlap (1-195:1-193) 10 20 30 40 50 60 pF1KB9 MNPVYSPGSSGVPYANAKGIGYPAGFPMGYAAAAPAYSPNMYPGANPTFQTGYTPGTPYK ::::::: . :.::.: :...: .:.: .: ::::::.:..:: .:.. ::: ::::: XP_016 MNPVYSPVQPGAPYGNPKNMAY-TGYPTAYPAAAPAYNPSLYPTNSPSYAPGYTAGTPYK 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 VSCSPTSGAVPPYSSSPNPYQTAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTT : . .. : :::: ::::::::.::.:::::::. ::: :.:::::.::: :::::::: XP_016 VPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQ-GAYYTQPVYAAQPHVIHHTT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 VVQPNGMPATVYPAPIPPPRGNGVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTY :::::..:...::::. :: :::.::::::::::::::::::. . : .. :::..::: XP_016 VVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTY 120 130 140 150 160 170 190 pF1KB9 RAPGTPTYSYVPPQW :: :::.::::::.: XP_016 RAQGTPAYSYVPPHW 180 190 >>NP_055974 (OMIM: 616316) protein FAM168A isoform 2 [Ho (235 aa) initn: 955 init1: 510 opt: 731 Z-score: 417.7 bits: 84.3 E(85289): 1.6e-16 Smith-Waterman score: 779; 54.2% identity (70.9% similar) in 227 aa overlap (11-195:11-235) 10 20 30 40 pF1KB9 MNPVYSPGSSGVPYANAKGIGYPAGFPMGYAAAAPAYSPNMYPGANPTF----------- :.::.: :...: .:.: .: ::::::.:..:: .:.. NP_055 MNPVYSPVQPGAPYGNPKNMAY-TGYPTAYPAAAPAYNPSLYPTNSPSYAPATLLMKQAW 10 20 30 40 50 50 60 70 pF1KB9 -----------------QTG--------------YTPGTPYKVSCSPTSGAVPPYSSSPN .:: :: :::::: . .. : :::: ::: NP_055 PQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPN 60 70 80 90 100 110 80 90 100 110 120 130 pF1KB9 PYQTAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPATVYPAPIPP :::::.::.:::::::. ::: :.:::::.::: :::::::::::::..:...::::. NP_055 PYQTAMYPIRSAYPQQNLYAQ-GAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAA 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB9 PRGNGVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTYRAPGTPTYSYVPPQW :: :::.::::::::::::::::::. . : .. :::..::::: :::.::::::.: NP_055 PRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW 180 190 200 210 220 230 >>NP_001272979 (OMIM: 616316) protein FAM168A isoform 1 (244 aa) initn: 955 init1: 510 opt: 724 Z-score: 413.8 bits: 83.7 E(85289): 2.6e-16 Smith-Waterman score: 730; 52.8% identity (67.7% similar) in 229 aa overlap (18-195:18-244) 10 20 30 40 50 pF1KB9 MNPVYSPGSSGVPYANAKGIGYPAGFPMGYAAAAPAYSPNMYPGANPT----FQ------ :...: .:.: .: ::::::.:..:: .:. :: NP_001 MNPVYSPVQPGAPYGNPKNMAY-TGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAY 10 20 30 40 50 60 pF1KB9 ---------------------------TG--------------YTPGTPYKVSCSPTSGA :: :: :::::: . .. : NP_001 ATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTA 60 70 80 90 100 110 70 80 90 100 110 120 pF1KB9 VPPYSSSPNPYQTAVYPVRSAYPQQSPYAQQGTYYTQPLYAAPPHVIHHTTVVQPNGMPA :::: ::::::::.::.:::::::. ::: :.:::::.::: :::::::::::::..:. NP_001 PPPYSPSPNPYQTAMYPIRSAYPQQNLYAQ-GAYYTQPVYAAQPHVIHHTTVVQPNSIPS 120 130 140 150 160 170 130 140 150 160 170 180 pF1KB9 TVYPAPIPPPRGNGVTMGMVAGTTMAMSAGTLLTAHSPTPVAPHPVTVPTYRAPGTPTYS ..::::. :: :::.::::::::::::::::::. . : .. :::..::::: :::.:: NP_001 AIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYS 180 190 200 210 220 230 190 pF1KB9 YVPPQW ::::.: NP_001 YVPPHW 240 195 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:16:01 2016 done: Sat Nov 5 13:16:02 2016 Total Scan time: 6.320 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]