FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9295, 203 aa 1>>>pF1KB9295 203 - 203 aa - 203 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2973+/-0.000823; mu= 5.4769+/- 0.050 mean_var=152.9170+/-30.410, 0's: 0 Z-trim(113.4): 24 B-trim: 325 in 1/50 Lambda= 0.103716 statistics sampled from 14037 (14056) to 14037 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.779), E-opt: 0.2 (0.432), width: 16 Scan time: 1.460 The best scores are: opt bits E(32554) CCDS32314.1 HDGFRP3 gene_id:50810|Hs108|chr15 ( 203) 1376 216.6 8.1e-57 CCDS1156.1 HDGF gene_id:3068|Hs108|chr1 ( 240) 624 104.2 6.9e-23 CCDS83348.1 PSIP1 gene_id:11168|Hs108|chr9 ( 329) 613 102.6 2.7e-22 CCDS6480.1 PSIP1 gene_id:11168|Hs108|chr9 ( 333) 613 102.7 2.8e-22 CCDS6479.1 PSIP1 gene_id:11168|Hs108|chr9 ( 530) 613 102.8 3.9e-22 CCDS59336.1 HDGFRP2 gene_id:84717|Hs108|chr19 ( 670) 606 101.8 9.7e-22 CCDS42472.1 HDGFRP2 gene_id:84717|Hs108|chr19 ( 671) 606 101.8 9.7e-22 CCDS44247.1 HDGF gene_id:3068|Hs108|chr1 ( 256) 470 81.2 6.3e-16 CCDS44248.1 HDGF gene_id:3068|Hs108|chr1 ( 233) 465 80.4 9.8e-16 CCDS34347.1 HDGFL1 gene_id:154150|Hs108|chr6 ( 251) 449 78.0 5.4e-15 >>CCDS32314.1 HDGFRP3 gene_id:50810|Hs108|chr15 (203 aa) initn: 1376 init1: 1376 opt: 1376 Z-score: 1133.5 bits: 216.6 E(32554): 8.1e-57 Smith-Waterman score: 1376; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS 130 140 150 160 170 180 190 200 pF1KB9 EGGDAGNDTRNTTSDLQKTSEGT ::::::::::::::::::::::: CCDS32 EGGDAGNDTRNTTSDLQKTSEGT 190 200 >>CCDS1156.1 HDGF gene_id:3068|Hs108|chr1 (240 aa) initn: 636 init1: 576 opt: 624 Z-score: 524.4 bits: 104.2 E(32554): 6.9e-23 Smith-Waterman score: 661; 51.5% identity (69.6% similar) in 227 aa overlap (1-203:1-225) 10 20 30 40 50 pF1KB9 MARP-RPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGP :.: : .::: ::::::::::::::::::::.::.::: :::: .::::::::::::: CCDS11 MSRSNRQKEYKCGDLVFAKMKGYPHWPARIDEMPEAAVKSTANKYQVFFFGTHETAFLGP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 KDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSE--------TE ::::::.: :.:::: ::::::.:::::::::: :: .:::. :..: : .: CCDS11 KDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAE 70 80 90 100 110 120 120 130 140 150 160 pF1KB9 GEG---GNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKS---YTSKKSSKQSRKSPGD :.: :: :..::.::: : : .:.::::.. ::. . : : :.... :. CCDS11 GDGDKKGN-AEGSSDEEGKLVI-DEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGE 130 140 150 160 170 170 180 190 200 pF1KB9 EDDKDCKE---------EENKSSSEGGDAGNDTRNTTSDLQKTSEGT : . : :.:.. :: :.. . .. . .. :.: CCDS11 EKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHE 180 190 200 210 220 230 CCDS11 SL 240 >>CCDS83348.1 PSIP1 gene_id:11168|Hs108|chr9 (329 aa) initn: 604 init1: 572 opt: 613 Z-score: 513.6 bits: 102.6 E(32554): 2.7e-22 Smith-Waterman score: 613; 55.6% identity (78.8% similar) in 160 aa overlap (7-166:3-155) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK :..: :::.:::::::::::::.::.:.::::::.:: :::::::::::::::: CCDS83 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPK 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA :.:::.: :.:.:: :::::::::::::.::: :::.. :: .::.. .. : . . CCDS83 DIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS :.:. :. : : .:: . . . :. :.....:: ... CCDS83 VSKEDTDHEE-----KASNEDV--TKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTAT 120 130 140 150 160 190 200 pF1KB9 EGGDAGNDTRNTTSDLQKTSEGT CCDS83 ASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKK 170 180 190 200 210 220 >>CCDS6480.1 PSIP1 gene_id:11168|Hs108|chr9 (333 aa) initn: 604 init1: 572 opt: 613 Z-score: 513.6 bits: 102.7 E(32554): 2.8e-22 Smith-Waterman score: 613; 55.6% identity (78.8% similar) in 160 aa overlap (7-166:3-155) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK :..: :::.:::::::::::::.::.:.::::::.:: :::::::::::::::: CCDS64 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPK 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA :.:::.: :.:.:: :::::::::::::.::: :::.. :: .::.. .. : . . CCDS64 DIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS :.:. :. : : .:: . . . :. :.....:: ... CCDS64 VSKEDTDHEE-----KASNEDV--TKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTAT 120 130 140 150 160 190 200 pF1KB9 EGGDAGNDTRNTTSDLQKTSEGT CCDS64 ASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKK 170 180 190 200 210 220 >>CCDS6479.1 PSIP1 gene_id:11168|Hs108|chr9 (530 aa) initn: 626 init1: 572 opt: 613 Z-score: 510.8 bits: 102.8 E(32554): 3.9e-22 Smith-Waterman score: 613; 55.6% identity (78.8% similar) in 160 aa overlap (7-166:3-155) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK :..: :::.:::::::::::::.::.:.::::::.:: :::::::::::::::: CCDS64 MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPK 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADA :.:::.: :.:.:: :::::::::::::.::: :::.. :: .::.. .. : . . CCDS64 DIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETS 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 SSEEEGDRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKEEENKSSS :.:. :. : : .:: . . . :. :.....:: ... CCDS64 VSKEDTDHEE-----KASNEDV--TKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTAT 120 130 140 150 160 190 200 pF1KB9 EGGDAGNDTRNTTSDLQKTSEGT CCDS64 ASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKK 170 180 190 200 210 220 >>CCDS59336.1 HDGFRP2 gene_id:84717|Hs108|chr19 (670 aa) initn: 704 init1: 571 opt: 606 Z-score: 503.8 bits: 101.8 E(32554): 9.7e-22 Smith-Waterman score: 645; 50.0% identity (73.5% similar) in 200 aa overlap (6-188:2-201) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK :. .: :::::::::::::::::::.. .:::::: ::::::::::::::::::: CCDS59 MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPK 10 20 30 40 50 70 80 90 100 110 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGE--GGNTA ::::: . :::.:: :::::::::::::.::: ..... .....: :.. :. : CCDS59 DLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDA 60 70 80 90 100 110 120 130 140 150 160 pF1KB9 DASSEEEG-------------DRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGD : ..:..: ::.: :. . ......: ::: . . ::..::. .: CCDS59 DEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSD 120 130 140 150 160 170 170 180 190 200 pF1KB9 EDDKDCK--EEENKSSSEGGDAGNDTRNTTSDLQKTSEGT :. . . ::::. :: .. .: CCDS59 LDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDS 180 190 200 210 220 230 >>CCDS42472.1 HDGFRP2 gene_id:84717|Hs108|chr19 (671 aa) initn: 704 init1: 571 opt: 606 Z-score: 503.8 bits: 101.8 E(32554): 9.7e-22 Smith-Waterman score: 645; 50.0% identity (73.5% similar) in 200 aa overlap (6-188:2-201) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK :. .: :::::::::::::::::::.. .:::::: ::::::::::::::::::: CCDS42 MPHAFKPGDLVFAKMKGYPHWPARIDDIADGAVKPPPNKYPIFFFGTHETAFLGPK 10 20 30 40 50 70 80 90 100 110 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGE--GGNTA ::::: . :::.:: :::::::::::::.::: ..... .....: :.. :. : CCDS42 DLFPYDKCKDKYGKPNKRKGFNEGLWEIQNNPHASYSAPPPVSSSDSEAPEANPADGSDA 60 70 80 90 100 110 120 130 140 150 160 pF1KB9 DASSEEEG-------------DRVEEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGD : ..:..: ::.: :. . ......: ::: . . ::..::. .: CCDS42 DEDDEDRGVMAVTAVTATAASDRMESDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSD 120 130 140 150 160 170 170 180 190 200 pF1KB9 EDDKDCK--EEENKSSSEGGDAGNDTRNTTSDLQKTSEGT :. . . ::::. :: .. .: CCDS42 LDQASVSPSEEENSESSSESEKTSDQDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDS 180 190 200 210 220 230 >>CCDS44247.1 HDGF gene_id:3068|Hs108|chr1 (256 aa) initn: 486 init1: 426 opt: 470 Z-score: 399.5 bits: 81.2 E(32554): 6.3e-16 Smith-Waterman score: 507; 47.3% identity (66.7% similar) in 201 aa overlap (26-203:43-241) 10 20 30 40 50 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETA : :::.::.::: :::: .::::::::: CCDS44 LGHLLATKLKRFLLSKGGRRAQIPDVSRATPHTIDEMPEAAVKSTANKYQVFFFGTHETA 20 30 40 50 60 70 60 70 80 90 100 pF1KB9 FLGPKDLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSE------ ::::::::::.: :.:::: ::::::.:::::::::: :: .:::. :..: : CCDS44 FLGPKDLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEP 80 90 100 110 120 130 110 120 130 140 150 160 pF1KB9 --TEGEG---GNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKS---YTSKKSSKQSRK .::.: :: :..::.::: : : .:.::::.. ::. . : : :.... CCDS44 EAAEGDGDKKGN-AEGSSDEEGKLVI-DEPAKEKNEKGALKRRAGDLLEDSPKRPKEAEN 140 150 160 170 180 190 170 180 190 200 pF1KB9 SPGDEDDKDCKE---------EENKSSSEGGDAGNDTRNTTSDLQKTSEGT :.: . : :.:.. :: :.. . .. . .. :.: CCDS44 PEGEEKEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGI 200 210 220 230 240 250 CCDS44 RDHESL >>CCDS44248.1 HDGF gene_id:3068|Hs108|chr1 (233 aa) initn: 488 init1: 428 opt: 465 Z-score: 396.0 bits: 80.4 E(32554): 9.8e-16 Smith-Waterman score: 502; 47.5% identity (67.0% similar) in 200 aa overlap (27-203:21-218) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK : :::.::.::: :::: .:::::::::::::: CCDS44 MEQRAGGNRVQTSTLNCAGAAVIDEMPEAAVKSTANKYQVFFFGTHETAFLGPK 10 20 30 40 50 70 80 90 100 110 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSE--------TEG :::::.: :.:::: ::::::.:::::::::: :: .:::. :..: : .:: CCDS44 DLFPYEESKEKFGKPNKRKGFSEGLWEIENNPTVKASGYQSSQKKSCVEEPEPEPEAAEG 60 70 80 90 100 110 120 130 140 150 160 pF1KB9 EG---GNTADASSEEEGDRVEEDGKGKRKNEKAGSKRKKS---YTSKKSSKQSRKSPGDE .: :: :..::.::: : : .:.::::.. ::. . : : :.... :.: CCDS44 DGDKKGN-AEGSSDEEGKLVI-DEPAKEKNEKGALKRRAGDLLEDSPKRPKEAENPEGEE 120 130 140 150 160 170 170 180 190 200 pF1KB9 DDKDCKE---------EENKSSSEGGDAGNDTRNTTSDLQKTSEGT . : :.:.. :: :.. . .. . .. :.: CCDS44 KEAATLEVERPLPMEVEKNSTPSEPGSGRGPPQEEEEEEDEEEEATKEDAEAPGIRDHES 180 190 200 210 220 230 CCDS44 L >>CCDS34347.1 HDGFL1 gene_id:154150|Hs108|chr6 (251 aa) initn: 483 init1: 301 opt: 449 Z-score: 382.6 bits: 78.0 E(32554): 5.4e-15 Smith-Waterman score: 449; 41.2% identity (66.0% similar) in 194 aa overlap (9-195:9-192) 10 20 30 40 50 60 pF1KB9 MARPRPREYKAGDLVFAKMKGYPHWPARIDELPEGAVKPPANKYPIFFFGTHETAFLGPK ::.:::::::.::: ::::::... ..: :.: .:::::::::::.:: CCDS34 MSAYGMPMYKSGDLVFAKLKGYAHWPARIEHM----TQP--NRYQVFFFGTHETAFLSPK 10 20 30 40 50 70 80 90 100 110 pF1KB9 DLFPYKEYKDKFGKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSS-----ETEG-EG :::::: :.:::: :::.::. ::::::::: :. . ....:. : :. :: CCDS34 RLFPYKECKEKFGKPNKRRGFSAGLWEIENNPTVQASDCPLASEKGSGDGPWPEPEAAEG 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 GNTADASSEEEGDRV-EEDGKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPGDEDDKDCKE . . . ::.. . : ..::. ::. . . . :. ... :... : CCDS34 DEDKPTHAGGGGDELGKPDDDKPTEEEKGPLKRSAGDPPEDAPKRPKEAAPDQEE----E 120 130 140 150 160 170 180 190 200 pF1KB9 EENKSSSEGGDAGNDTRNTTSDLQKTSEGT : . ..:. :. . :. : CCDS34 AEAERAAEAERAAAAAAATAVDEESPFLVAVENGSAPSEPGLVCEPPQPEEEELREEEVA 180 190 200 210 220 230 203 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:17:13 2016 done: Sat Nov 5 13:17:14 2016 Total Scan time: 1.460 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]