FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9348, 273 aa 1>>>pF1KB9348 273 - 273 aa - 273 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1590+/-0.000721; mu= 7.3544+/- 0.044 mean_var=110.4149+/-21.519, 0's: 0 Z-trim(113.1): 31 B-trim: 2 in 1/52 Lambda= 0.122056 statistics sampled from 13751 (13778) to 13751 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.771), E-opt: 0.2 (0.423), width: 16 Scan time: 2.590 The best scores are: opt bits E(32554) CCDS46716.1 TEF gene_id:7008|Hs108|chr22 ( 273) 1784 324.0 6.9e-89 CCDS14014.1 TEF gene_id:7008|Hs108|chr22 ( 303) 1668 303.6 1.1e-82 CCDS11585.1 HLF gene_id:3131|Hs108|chr17 ( 295) 1002 186.3 2.1e-47 CCDS82164.1 HLF gene_id:3131|Hs108|chr17 ( 210) 815 153.4 1.3e-37 CCDS12728.1 DBP gene_id:1628|Hs108|chr19 ( 325) 753 142.5 3.6e-34 >>CCDS46716.1 TEF gene_id:7008|Hs108|chr22 (273 aa) initn: 1784 init1: 1784 opt: 1784 Z-score: 1709.3 bits: 324.0 E(32554): 6.9e-89 Smith-Waterman score: 1784; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273) 10 20 30 40 50 60 pF1KB9 MDMPEVLKSLLEHSLPWPEKRTDKEKGKEKLEEDEAAAASTMAVSASLMPPIWDKTIPYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 MDMPEVLKSLLEHSLPWPEKRTDKEKGKEKLEEDEAAAASTMAVSASLMPPIWDKTIPYD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 GESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAELEGKESASSSTASPPSSSTAIFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAELEGKESASSSTASPPSSSTAIFQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 PSETVSSTESSLEKERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 PSETVSSTESSLEKERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 EDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 EDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEK 190 200 210 220 230 240 250 260 270 pF1KB9 ENTALRTEVAELRKEVGKCKTIVSKYETKYGPL ::::::::::::::::::::::::::::::::: CCDS46 ENTALRTEVAELRKEVGKCKTIVSKYETKYGPL 250 260 270 >>CCDS14014.1 TEF gene_id:7008|Hs108|chr22 (303 aa) initn: 1641 init1: 1641 opt: 1668 Z-score: 1598.2 bits: 303.6 E(32554): 1.1e-82 Smith-Waterman score: 1668; 96.3% identity (97.4% similar) in 270 aa overlap (4-273:36-303) 10 20 30 pF1KB9 MDMPEVLKSLLEHSLPWPEKRTDKEKGKEKLEE : :::.:.:. : : : ::::::::::: CCDS14 GGKKPPVDPQAGPGPGPGRAAGERGLSGSFPLVLKKLMEN--PPREARLDKEKGKEKLEE 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 DEAAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 DEAAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB9 PVAELEGKESASSSTASPPSSSTAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 PVAELEGKESASSSTASPPSSSTAIFQPSETVSSTESSLEKERETPSPIDPNCVEVDVNF 130 140 150 160 170 180 160 170 180 190 200 210 pF1KB9 NPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKN 190 200 210 220 230 240 220 230 240 250 260 270 pF1KB9 NVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYGPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 NVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYGPL 250 260 270 280 290 300 >>CCDS11585.1 HLF gene_id:3131|Hs108|chr17 (295 aa) initn: 978 init1: 732 opt: 1002 Z-score: 964.5 bits: 186.3 E(32554): 2.1e-47 Smith-Waterman score: 1002; 56.8% identity (79.1% similar) in 278 aa overlap (6-273:21-295) 10 20 30 40 pF1KB9 MDMPEVLKSLLEHSLPWPEKRTD---KEKGKEKLEEDEAAAASTM ::.::::. : : .. : :.: ::: .::. . :. CCDS11 MEKMSRPLPLNPTFIPPPYGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSP-TV 10 20 30 40 50 50 60 70 80 90 100 pF1KB9 AVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAELEGKE :: : : .::::.::::..:.::::::.::: ::::: ::.. :. : :. CCDS11 PQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPP--GLQPAS 60 70 80 90 100 110 110 120 130 140 150 pF1KB9 SASSSTASPPSSSTAIFQPSETVSSTESS-------LEKERETPSPIDPNCVEVDVNFNP ::. :. . : ..: ..:. . .: : .:.:::::::. ..: :...: CCDS11 SAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEP 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 DPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRKKNNV :::::.:::.:: :.:.:::.::.::.::::::::::.:::.::. ::.:::.::.:::. CCDS11 DPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRRKNNM 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB9 AAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYGPL ::::::::::::::::.:::.::::::.::: :::.::::.::::.:..:::...::: CCDS11 AAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL 240 250 260 270 280 290 >>CCDS82164.1 HLF gene_id:3131|Hs108|chr17 (210 aa) initn: 809 init1: 732 opt: 815 Z-score: 788.9 bits: 153.4 E(32554): 1.3e-37 Smith-Waterman score: 815; 59.0% identity (81.6% similar) in 212 aa overlap (69-273:1-210) 40 50 60 70 80 90 pF1KB9 ASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLENGIPASPTHLAHNLLLPVAEL :::.::: ::::: ::.. :. : : CCDS82 MDLEEFLSENGIPPSPSQHDHSPHPP--GL 10 20 100 110 120 130 140 150 pF1KB9 EGKESASSSTASPPSSSTAIFQPSETVSSTESS-------LEKERETPSPIDPNCVEVDV . ::. :. . : ..: ..:. . .: : .:.:::::::. ..: : CCDS82 QPASSAAPSVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPV 30 40 50 60 70 80 160 170 180 190 200 210 pF1KB9 NFNPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKKAKKVFVPDEQKDEKYWTRRK ...::::::.:::.:: :.:.:::.::.::.::::::::::.:::.::. ::.:::.::. CCDS82 GYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKDDKYWARRR 90 100 110 120 130 140 220 230 240 250 260 270 pF1KB9 KNNVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAELRKEVGKCKTIVSKYETKYG :::.::::::::::::::::.:::.::::::.::: :::.::::.::::.:..:::...: CCDS82 KNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHG 150 160 170 180 190 200 pF1KB9 PL :: CCDS82 PL 210 >>CCDS12728.1 DBP gene_id:1628|Hs108|chr19 (325 aa) initn: 738 init1: 638 opt: 753 Z-score: 726.9 bits: 142.5 E(32554): 3.6e-34 Smith-Waterman score: 753; 51.3% identity (76.3% similar) in 232 aa overlap (48-273:100-325) 20 30 40 50 60 70 pF1KB9 PEKRTDKEKGKEKLEEDEAAAASTMAVSASLMPPIWDKTIPYDGESFHLEYMDLDEFLLE : : .:..:.:. :. .::.::: :::: CCDS12 TAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPF-GD---VEYVDLDAFLLE 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB9 NGIPASPTHLAHNLLLPVAELEGKES---ASSSTASPPSSSTAIFQPSETVSSTESSLEK .:.: :: . : : .: ..::: :: :.... .: :. . CCDS12 HGLPPSPPPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPG--HAPARAALGTASGHRA 130 140 150 160 170 180 140 150 160 170 180 190 pF1KB9 ---ERETPSPIDPNCVEVDVNFNPDPADLVLSSVPGGELFNPRKHKFAEEDLKPQPMIKK :.::::.::. ::: ..:.::::::.:::.:: : :.::.:.:.::.:::::..:: CCDS12 GLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPIMKK 190 200 210 220 230 240 200 210 220 230 240 250 pF1KB9 AKKVFVPDEQKDEKYWTRRKKNNVAAKRSRDARRLKENQITIRAAFLEKENTALRTEVAE :.:. ::.::::::::.:: ::: ::::::::::::::::..:::::::::. :: ::. CCDS12 ARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVA 250 260 270 280 290 300 260 270 pF1KB9 LRKEVGKCKTIVSKYETKYGPL .:.:... ....:.:....: : CCDS12 VRQELSHYRAVLSRYQAQHGAL 310 320 273 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:22:13 2016 done: Thu Nov 3 18:22:14 2016 Total Scan time: 2.590 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]