FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9351, 1944 aa 1>>>pF1KB9351 1944 - 1944 aa - 1944 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5021+/-0.000438; mu= 18.8177+/- 0.027 mean_var=97.8948+/-20.060, 0's: 0 Z-trim(111.8): 40 B-trim: 527 in 1/58 Lambda= 0.129627 statistics sampled from 20416 (20444) to 20416 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.24), width: 16 Scan time: 22.010 The best scores are: opt bits E(85289) NP_073153 (OMIM: 608473) anaphase-promoting comple (1944) 12962 2436.1 0 XP_011509935 (OMIM: 608473) PREDICTED: anaphase-pr (1948) 12944 2432.7 0 XP_016860200 (OMIM: 608473) PREDICTED: anaphase-pr (1917) 12725 2391.7 0 XP_016860199 (OMIM: 608473) PREDICTED: anaphase-pr (1921) 12707 2388.4 0 XP_016860201 (OMIM: 608473) PREDICTED: anaphase-pr (1846) 12301 2312.4 0 XP_011509936 (OMIM: 608473) PREDICTED: anaphase-pr (1850) 12283 2309.1 0 XP_016860203 (OMIM: 608473) PREDICTED: anaphase-pr (1784) 11885 2234.6 0 XP_016860202 (OMIM: 608473) PREDICTED: anaphase-pr (1788) 11867 2231.3 0 XP_016860204 (OMIM: 608473) PREDICTED: anaphase-pr (1473) 9555 1798.9 0 XP_011509938 (OMIM: 608473) PREDICTED: anaphase-pr (1079) 7111 1341.7 0 XP_011509939 (OMIM: 608473) PREDICTED: anaphase-pr (1031) 6658 1257.0 0 XP_016860339 (OMIM: 612705) PREDICTED: RANBP2-like (1813) 1182 233.0 2.1e-59 XP_016860338 (OMIM: 612705) PREDICTED: RANBP2-like (1814) 1182 233.0 2.1e-59 XP_016860337 (OMIM: 612705) PREDICTED: RANBP2-like (1828) 1182 233.0 2.1e-59 XP_016860334 (OMIM: 612705) PREDICTED: RANBP2-like (1917) 1182 233.1 2.2e-59 XP_011531154 (OMIM: 612704) PREDICTED: RANBP2-like (1697) 496 104.7 8.3e-21 XP_011531153 (OMIM: 612704) PREDICTED: RANBP2-like (1698) 496 104.7 8.3e-21 XP_011531152 (OMIM: 612704) PREDICTED: RANBP2-like (1712) 496 104.7 8.4e-21 XP_011531151 (OMIM: 612704) PREDICTED: RANBP2-like (1724) 496 104.7 8.4e-21 XP_016859596 (OMIM: 612704) PREDICTED: RANBP2-like (1740) 496 104.7 8.5e-21 XP_011531147 (OMIM: 612704) PREDICTED: RANBP2-like (1801) 496 104.8 8.7e-21 XP_016859592 (OMIM: 612704) PREDICTED: RANBP2-like (1805) 496 104.8 8.7e-21 XP_016859593 (OMIM: 612704) PREDICTED: RANBP2-like (1780) 316 71.1 1.2e-10 >>NP_073153 (OMIM: 608473) anaphase-promoting complex su (1944 aa) initn: 12962 init1: 12962 opt: 12962 Z-score: 13093.0 bits: 2436.1 E(85289): 0 Smith-Waterman score: 12962; 100.0% identity (100.0% similar) in 1944 aa overlap (1-1944:1-1944) 10 20 30 40 50 60 pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_073 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQ 1870 1880 1890 1900 1910 1920 1930 1940 pF1KB9 LKMPVRALLRLAPLLLGNPQPMVM :::::::::::::::::::::::: NP_073 LKMPVRALLRLAPLLLGNPQPMVM 1930 1940 >>XP_011509935 (OMIM: 608473) PREDICTED: anaphase-promot (1948 aa) initn: 6665 init1: 6665 opt: 12944 Z-score: 13074.8 bits: 2432.7 E(85289): 0 Smith-Waterman score: 12944; 99.8% identity (99.8% similar) in 1948 aa overlap (1-1944:1-1948) 10 20 30 40 50 60 pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB9 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB9 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB9 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB9 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB9 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB9 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB9 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB9 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB9 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KB9 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KB9 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KB9 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KB9 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLF 1870 1880 1890 1900 1910 1920 1920 1930 1940 pF1KB9 KFKQLKMPVRALLRLAPLLLGNPQPMVM :::::::::::::::::::::::::::: XP_011 KFKQLKMPVRALLRLAPLLLGNPQPMVM 1930 1940 >>XP_016860200 (OMIM: 608473) PREDICTED: anaphase-promot (1917 aa) initn: 12725 init1: 12725 opt: 12725 Z-score: 12853.5 bits: 2391.7 E(85289): 0 Smith-Waterman score: 12725; 100.0% identity (100.0% similar) in 1907 aa overlap (1-1907:1-1907) 10 20 30 40 50 60 pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY 910 920 930 940 950 960 970 980 990 1000 1010 1020 pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMN 970 980 990 1000 1010 1020 1030 1040 1050 1060 1070 1080 pF1KB9 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMAL 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 1140 pF1KB9 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNG 1090 1100 1110 1120 1130 1140 1150 1160 1170 1180 1190 1200 pF1KB9 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKG 1150 1160 1170 1180 1190 1200 1210 1220 1230 1240 1250 1260 pF1KB9 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLV 1210 1220 1230 1240 1250 1260 1270 1280 1290 1300 1310 1320 pF1KB9 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLN 1270 1280 1290 1300 1310 1320 1330 1340 1350 1360 1370 1380 pF1KB9 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNN 1330 1340 1350 1360 1370 1380 1390 1400 1410 1420 1430 1440 pF1KB9 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSIS 1390 1400 1410 1420 1430 1440 1450 1460 1470 1480 1490 1500 pF1KB9 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLS 1450 1460 1470 1480 1490 1500 1510 1520 1530 1540 1550 1560 pF1KB9 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHM 1510 1520 1530 1540 1550 1560 1570 1580 1590 1600 1610 1620 pF1KB9 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLV 1570 1580 1590 1600 1610 1620 1630 1640 1650 1660 1670 1680 pF1KB9 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDL 1630 1640 1650 1660 1670 1680 1690 1700 1710 1720 1730 1740 pF1KB9 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISA 1690 1700 1710 1720 1730 1740 1750 1760 1770 1780 1790 1800 pF1KB9 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRL 1750 1760 1770 1780 1790 1800 1810 1820 1830 1840 1850 1860 pF1KB9 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWL 1810 1820 1830 1840 1850 1860 1870 1880 1890 1900 1910 1920 pF1KB9 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQ ::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGLLKDLAGDSG 1870 1880 1890 1900 1910 1930 1940 pF1KB9 LKMPVRALLRLAPLLLGNPQPMVM >>XP_016860199 (OMIM: 608473) PREDICTED: anaphase-promot (1921 aa) initn: 6665 init1: 6665 opt: 12707 Z-score: 12835.3 bits: 2388.4 E(85289): 0 Smith-Waterman score: 12707; 99.8% identity (99.8% similar) in 1911 aa overlap (1-1907:1-1911) 10 20 30 40 50 60 pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_016 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB9 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB9 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB9 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB9 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB9 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB9 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM 1450 1460 1470 1480 1490 1500 1500 1510 1520 1530 1540 1550 pF1KB9 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHL 1510 1520 1530 1540 1550 1560 1560 1570 1580 1590 1600 1610 pF1KB9 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEP 1570 1580 1590 1600 1610 1620 1620 1630 1640 1650 1660 1670 pF1KB9 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RLLVPVDVDTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWEL 1630 1640 1650 1660 1670 1680 1680 1690 1700 1710 1720 1730 pF1KB9 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LIDLSKGTQHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPE 1690 1700 1710 1720 1730 1740 1740 1750 1760 1770 1780 1790 pF1KB9 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TISAFTSDPALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQA 1750 1760 1770 1780 1790 1800 1800 1810 1820 1830 1840 1850 pF1KB9 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IRRLGRREMSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTL 1810 1820 1830 1840 1850 1860 1860 1870 1880 1890 1900 1910 pF1KB9 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLF ::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DQWLQVGGDMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGLLKDLAGDS 1870 1880 1890 1900 1910 1920 1920 1930 1940 pF1KB9 KFKQLKMPVRALLRLAPLLLGNPQPMVM XP_016 G >>XP_016860201 (OMIM: 608473) PREDICTED: anaphase-promot (1846 aa) initn: 12301 init1: 12301 opt: 12301 Z-score: 12425.3 bits: 2312.4 E(85289): 0 Smith-Waterman score: 12301; 100.0% identity (100.0% similar) in 1846 aa overlap (99-1944:1-1846) 70 80 90 100 110 120 pF1KB9 KQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALW :::::::::::::::::::::::::::::: XP_016 MVIWSKGSKSQALAVYKAFTVDSPVQQALW 10 20 30 130 140 150 160 170 180 pF1KB9 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB9 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB9 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB9 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB9 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB9 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB9 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB9 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB9 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM 520 530 540 550 560 570 670 680 690 700 710 720 pF1KB9 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL 580 590 600 610 620 630 730 740 750 760 770 780 pF1KB9 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE 640 650 660 670 680 690 790 800 810 820 830 840 pF1KB9 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV 700 710 720 730 740 750 850 860 870 880 890 900 pF1KB9 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV 760 770 780 790 800 810 910 920 930 940 950 960 pF1KB9 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS 820 830 840 850 860 870 970 980 990 1000 1010 1020 pF1KB9 DWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DWPEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIW 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KB9 SEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFT 940 950 960 970 980 990 1090 1100 1110 1120 1130 1140 pF1KB9 LFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIA 1000 1010 1020 1030 1040 1050 1150 1160 1170 1180 1190 1200 pF1KB9 PASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGL 1060 1070 1080 1090 1100 1110 1210 1220 1230 1240 1250 1260 pF1KB9 LLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRH 1120 1130 1140 1150 1160 1170 1270 1280 1290 1300 1310 1320 pF1KB9 TAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQY 1180 1190 1200 1210 1220 1230 1330 1340 1350 1360 1370 1380 pF1KB9 MVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLR 1240 1250 1260 1270 1280 1290 1390 1400 1410 1420 1430 1440 pF1KB9 APDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPC 1300 1310 1320 1330 1340 1350 1450 1460 1470 1480 1490 1500 pF1KB9 SEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTG 1360 1370 1380 1390 1400 1410 1510 1520 1530 1540 1550 1560 pF1KB9 PHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLG 1420 1430 1440 1450 1460 1470 1570 1580 1590 1600 1610 1620 pF1KB9 GGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNT 1480 1490 1500 1510 1520 1530 1630 1640 1650 1660 1670 1680 pF1KB9 PCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLK 1540 1550 1560 1570 1580 1590 1690 1700 1710 1720 1730 1740 pF1KB9 SILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALL 1600 1610 1620 1630 1640 1650 1750 1760 1770 1780 1790 1800 pF1KB9 SFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSET 1660 1670 1680 1690 1700 1710 1810 1820 1830 1840 1850 1860 pF1KB9 SELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCV 1720 1730 1740 1750 1760 1770 1870 1880 1890 1900 1910 1920 pF1KB9 HAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRAL 1780 1790 1800 1810 1820 1830 1930 1940 pF1KB9 LRLAPLLLGNPQPMVM :::::::::::::::: XP_016 LRLAPLLLGNPQPMVM 1840 >>XP_011509936 (OMIM: 608473) PREDICTED: anaphase-promot (1850 aa) initn: 6308 init1: 6308 opt: 12283 Z-score: 12407.0 bits: 2309.1 E(85289): 0 Smith-Waterman score: 12283; 99.8% identity (99.8% similar) in 1850 aa overlap (99-1944:1-1850) 70 80 90 100 110 120 pF1KB9 KQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSPVQQALW :::::::::::::::::::::::::::::: XP_011 MVIWSKGSKSQALAVYKAFTVDSPVQQALW 10 20 30 130 140 150 160 170 180 pF1KB9 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLL 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB9 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVF 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB9 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSL 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB9 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQR 220 230 240 250 260 270 370 380 390 400 410 420 pF1KB9 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQAS 280 290 300 310 320 330 430 440 450 460 470 480 pF1KB9 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTM 340 350 360 370 380 390 490 500 510 520 530 540 pF1KB9 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSL 400 410 420 430 440 450 550 560 570 580 590 600 pF1KB9 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRIT 460 470 480 490 500 510 610 620 630 640 650 660 pF1KB9 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMM 520 530 540 550 560 570 670 680 690 700 710 720 pF1KB9 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSL 580 590 600 610 620 630 730 740 750 760 770 780 pF1KB9 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVE 640 650 660 670 680 690 790 800 810 820 830 840 pF1KB9 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWV 700 710 720 730 740 750 850 860 870 880 890 900 pF1KB9 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQV 760 770 780 790 800 810 910 920 930 940 950 960 pF1KB9 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPAS 820 830 840 850 860 870 970 980 990 1000 1010 1020 pF1KB9 DWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGMNDMNHEVM ::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: XP_011 DWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGMNDMNHEVM 880 890 900 910 920 930 1030 1040 1050 1060 1070 1080 pF1KB9 SLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGR 940 950 960 970 980 990 1090 1100 1110 1120 1130 1140 pF1KB9 GMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAG 1000 1010 1020 1030 1040 1050 1150 1160 1170 1180 1190 1200 pF1KB9 LKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMT 1060 1070 1080 1090 1100 1110 1210 1220 1230 1240 1250 1260 pF1KB9 SIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGT 1120 1130 1140 1150 1160 1170 1270 1280 1290 1300 1310 1320 pF1KB9 AHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 AHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQ 1180 1190 1200 1210 1220 1230 1330 1340 1350 1360 1370 1380 pF1KB9 LYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIA 1240 1250 1260 1270 1280 1290 1390 1400 1410 1420 1430 1440 pF1KB9 DWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEI 1300 1310 1320 1330 1340 1350 1450 1460 1470 1480 1490 1500 pF1KB9 ELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNA 1360 1370 1380 1390 1400 1410 1510 1520 1530 1540 1550 1560 pF1KB9 SVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGL 1420 1430 1440 1450 1460 1470 1570 1580 1590 1600 1610 1620 pF1KB9 LFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LFLGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDV 1480 1490 1500 1510 1520 1530 1630 1640 1650 1660 1670 1680 pF1KB9 DTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DTNTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGT 1540 1550 1560 1570 1580 1590 1690 1700 1710 1720 1730 1740 pF1KB9 QHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QHLKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSD 1600 1610 1620 1630 1640 1650 1750 1760 1770 1780 1790 1800 pF1KB9 PALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRRE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PALLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRRE 1660 1670 1680 1690 1700 1710 1810 1820 1830 1840 1850 1860 pF1KB9 MSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGG 1720 1730 1740 1750 1760 1770 1870 1880 1890 1900 1910 1920 pF1KB9 DMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DMCVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMP 1780 1790 1800 1810 1820 1830 1930 1940 pF1KB9 VRALLRLAPLLLGNPQPMVM :::::::::::::::::::: XP_011 VRALLRLAPLLLGNPQPMVM 1840 1850 >>XP_016860203 (OMIM: 608473) PREDICTED: anaphase-promot (1784 aa) initn: 11885 init1: 11885 opt: 11885 Z-score: 12005.0 bits: 2234.6 E(85289): 0 Smith-Waterman score: 11885; 100.0% identity (100.0% similar) in 1784 aa overlap (161-1944:1-1784) 140 150 160 170 180 190 pF1KB9 FIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFE :::::::::::::::::::::::::::::: XP_016 MHSIEGKDYIASLPFQVANVWPTKYGLLFE 10 20 30 200 210 220 230 240 250 pF1KB9 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB9 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB9 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB9 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB9 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB9 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB9 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB9 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY 460 470 480 490 500 510 680 690 700 710 720 730 pF1KB9 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL 520 530 540 550 560 570 740 750 760 770 780 790 pF1KB9 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL 580 590 600 610 620 630 800 810 820 830 840 850 pF1KB9 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS 640 650 660 670 680 690 860 870 880 890 900 910 pF1KB9 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ 700 710 720 730 740 750 920 930 940 950 960 970 pF1KB9 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW 760 770 780 790 800 810 980 990 1000 1010 1020 1030 pF1KB9 PEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIWSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEAVCLLIGRQDLSKQACEGNLPKGKSVLSSDVPSGTETEEEDDGMNDMNHEVMSLIWSE 820 830 840 850 860 870 1040 1050 1060 1070 1080 1090 pF1KB9 DLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGMFTLF 880 890 900 910 920 930 1100 1110 1120 1130 1140 1150 pF1KB9 SYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLKIAPA 940 950 960 970 980 990 1160 1170 1180 1190 1200 1210 pF1KB9 SQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLL 1000 1010 1020 1030 1040 1050 1220 1230 1240 1250 1260 1270 pF1KB9 GVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRHTA 1060 1070 1080 1090 1100 1110 1280 1290 1300 1310 1320 1330 pF1KB9 EVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLYQYMV 1120 1130 1140 1150 1160 1170 1340 1350 1360 1370 1380 1390 pF1KB9 GGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADWLRAP 1180 1190 1200 1210 1220 1230 1400 1410 1420 1430 1440 1450 pF1KB9 DTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIELPCSE 1240 1250 1260 1270 1280 1290 1460 1470 1480 1490 1500 1510 pF1KB9 DLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASVTGPH 1300 1310 1320 1330 1340 1350 1520 1530 1540 1550 1560 1570 pF1KB9 NLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLFLGGG 1360 1370 1380 1390 1400 1410 1580 1590 1600 1610 1620 1630 pF1KB9 RYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPC 1420 1430 1440 1450 1460 1470 1640 1650 1660 1670 1680 1690 pF1KB9 YALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQHLKSI 1480 1490 1500 1510 1520 1530 1700 1710 1720 1730 1740 1750 pF1KB9 LSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPALLSF 1540 1550 1560 1570 1580 1590 1760 1770 1780 1790 1800 1810 pF1KB9 AEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSE 1600 1610 1620 1630 1640 1650 1820 1830 1840 1850 1860 1870 pF1KB9 LWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHA 1660 1670 1680 1690 1700 1710 1880 1890 1900 1910 1920 1930 pF1KB9 YLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVRALLR 1720 1730 1740 1750 1760 1770 1940 pF1KB9 LAPLLLGNPQPMVM :::::::::::::: XP_016 LAPLLLGNPQPMVM 1780 >>XP_016860202 (OMIM: 608473) PREDICTED: anaphase-promot (1788 aa) initn: 6308 init1: 6308 opt: 11867 Z-score: 11986.8 bits: 2231.3 E(85289): 0 Smith-Waterman score: 11867; 99.8% identity (99.8% similar) in 1788 aa overlap (161-1944:1-1788) 140 150 160 170 180 190 pF1KB9 FIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPTKYGLLFE :::::::::::::::::::::::::::::: XP_016 MHSIEGKDYIASLPFQVANVWPTKYGLLFE 10 20 30 200 210 220 230 240 250 pF1KB9 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVVDHAMKIVFLN 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB9 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSSLTAHLRSLSK 100 110 120 130 140 150 320 330 340 350 360 370 pF1KB9 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGVHSFSGVQRFN 160 170 180 190 200 210 380 390 400 410 420 430 pF1KB9 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNIREKNSQASKV 220 230 240 250 260 270 440 450 460 470 480 490 pF1KB9 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAAPVEKIDTMLV 280 290 300 310 320 330 500 510 520 530 540 550 pF1KB9 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKPLSKLLGSLDE 340 350 360 370 380 390 560 570 580 590 600 610 pF1KB9 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELSNGSMVRITIP 400 410 420 430 440 450 620 630 640 650 660 670 pF1KB9 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLFVTCLMNMMGY 460 470 480 490 500 510 680 690 700 710 720 730 pF1KB9 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVESHLLNRSLCL 520 530 540 550 560 570 740 750 760 770 780 790 pF1KB9 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMGEGICSLVELL 580 590 600 610 620 630 800 810 820 830 840 850 pF1KB9 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSEPPSIYQWVSS 640 650 660 670 680 690 860 870 880 890 900 910 pF1KB9 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRITIAPQKLQVEQ 700 710 720 730 740 750 920 930 940 950 960 970 pF1KB9 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIYHCREQPASDW 760 770 780 790 800 810 980 990 1000 1010 1020 pF1KB9 PEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGMNDMNHEVMSL ::::::::::::::::::::::::::: ::::::::::::::::::::::::::::: XP_016 PEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGMNDMNHEVMSL 820 830 840 850 860 870 1030 1040 1050 1060 1070 1080 pF1KB9 IWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQRTMALPVGRGM 880 890 900 910 920 930 1090 1100 1110 1120 1130 1140 pF1KB9 FTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWASFHNGVAAGLK 940 950 960 970 980 990 1150 1160 1170 1180 1190 1200 pF1KB9 IAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSI 1000 1010 1020 1030 1040 1050 1210 1220 1230 1240 1250 1260 pF1KB9 GLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAH 1060 1070 1080 1090 1100 1110 1270 1280 1290 1300 1310 1320 pF1KB9 RHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGMSDLNVPEQLY 1120 1130 1140 1150 1160 1170 1330 1340 1350 1360 1370 1380 pF1KB9 QYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYLKTNNRSIADW 1180 1190 1200 1210 1220 1230 1390 1400 1410 1420 1430 1440 pF1KB9 LRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRENSISLSEIEL 1240 1250 1260 1270 1280 1290 1450 1460 1470 1480 1490 1500 pF1KB9 PCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFMTYLSAPNASV 1300 1310 1320 1330 1340 1350 1510 1520 1530 1540 1550 1560 pF1KB9 TGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMKTGGEMNYGFHLAHHMALGLLF 1360 1370 1380 1390 1400 1410 1570 1580 1590 1600 1610 1620 pF1KB9 LGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGGGRYSLSTSNSSIAALLCALYPHFPAHSTDNRYHLQALRHLYVLAAEPRLLVPVDVDT 1420 1430 1440 1450 1460 1470 1630 1640 1650 1660 1670 1680 pF1KB9 NTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NTPCYALLEVTYKGTQWYEQTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLSKGTQH 1480 1490 1500 1510 1520 1530 1690 1700 1710 1720 1730 1740 pF1KB9 LKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKSILSKDGVLYVKLRAGQLSYKEDPMGWQSLLAQTVANRNSEARAFKPETISAFTSDPA 1540 1550 1560 1570 1580 1590 1750 1760 1770 1780 1790 1800 pF1KB9 LLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LLSFAEYFCKPTVNMGQKQEILDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMS 1600 1610 1620 1630 1640 1650 1810 1820 1830 1840 1850 1860 pF1KB9 ETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ETSELWQIKLVLEFFSSRSHQERLQNHPKRGLFMNSEFLPVVKCTIDNTLDQWLQVGGDM 1660 1670 1680 1690 1700 1710 1870 1880 1890 1900 1910 1920 pF1KB9 CVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CVHAYLSGQPLEESQLSMLACFLVYHSVPAPQHLPPIGLEGSTSFAELLFKFKQLKMPVR 1720 1730 1740 1750 1760 1770 1930 1940 pF1KB9 ALLRLAPLLLGNPQPMVM :::::::::::::::::: XP_016 ALLRLAPLLLGNPQPMVM 1780 >>XP_016860204 (OMIM: 608473) PREDICTED: anaphase-promot (1473 aa) initn: 9570 init1: 6665 opt: 9555 Z-score: 9651.4 bits: 1798.9 E(85289): 0 Smith-Waterman score: 9555; 99.5% identity (99.7% similar) in 1439 aa overlap (1-1435:1-1439) 10 20 30 40 50 60 pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_016 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR 1030 1040 1050 1060 1070 1080 1080 1090 1100 1110 1120 1130 pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS 1090 1100 1110 1120 1130 1140 1140 1150 1160 1170 1180 1190 pF1KB9 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FHNGVAAGLKIAPASQIDSAWIVYNKPKHAELANEYAGFLMALGLNGHLTKLATLNIHDY 1150 1160 1170 1180 1190 1200 1200 1210 1220 1230 1240 1250 pF1KB9 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LTKGHEMTSIGLLLGVSAAKLGTMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVG 1210 1220 1230 1240 1250 1260 1260 1270 1280 1290 1300 1310 pF1KB9 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGLVYQGTAHRHTAEVLLAEIGRPPGPEMEYCTDRESYSLAAGLALGMVCLGHGSNLIGM 1270 1280 1290 1300 1310 1320 1320 1330 1340 1350 1360 1370 pF1KB9 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SDLNVPEQLYQYMVGGHRRFQTGMHREKHKSPSYQIKEGDTINVDVTCPGATLALAMIYL 1330 1340 1350 1360 1370 1380 1380 1390 1400 1410 1420 1430 pF1KB9 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQIIRE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::... XP_016 KTNNRSIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVPQVVQI 1390 1400 1410 1420 1430 1440 1440 1450 1460 1470 1480 1490 pF1KB9 NSISLSEIELPCSEDLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDFM XP_016 EYFLSEMLGTRSVFGFWNTRNYTYWLSIPHLKL 1450 1460 1470 >>XP_011509938 (OMIM: 608473) PREDICTED: anaphase-promot (1079 aa) initn: 6659 init1: 6659 opt: 7111 Z-score: 7183.3 bits: 1341.7 E(85289): 0 Smith-Waterman score: 7111; 99.6% identity (99.6% similar) in 1073 aa overlap (1-1069:1-1073) 10 20 30 40 50 60 pF1KB9 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSNFYEERTTMIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASELWSSDGAAGLVGS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQEVTIHEKQKESWQLRKGVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPVQQALWCDFIISQDKSEKAYSSNEVEKCICILQSSCINMHSIEGKDYIASLPFQVANV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WPTKYGLLFERSASSHEVPPGSPREPLPTMFSMLHPLDEITPLVCKSGSLFGSSRVQYVV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DHAMKIVFLNTDPSIVMTYDAVQNVHSVWTLRRVKSEEENVVLKFSEQGGTPQNVATSSS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LTAHLRSLSKGDSPVTSPFQNYSSIHSQSRSTSSPSLHSRSPSISNMAALSRAHSPALGV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HSFSGVQRFNISSHNQSPKRHSISHSPNSNSNGSFLAPETEPIVPELCIDHLWTETITNI 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 REKNSQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESNDKTQLIFGSVTNIPAKDAA 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPGLPAPSLTMSNTMPRPSTPLDGVSTPKP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LSKLLGSLDEVVLLSPVPELRDSSKLHDSLYNEDCTFQQLGTYIHSIRDPVHNRVTLELS 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKWYNVHSAPGGPSYHSEWNLF 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VTCLMNMMGYNTDRLAWTRNFDFEGSLSPVIAPKKARPSETGSDDDWEYLLNSDYHQNVE 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SHLLNRSLCLSPSEASQMKDEDFSQNLSLDSSTLLFTHIPAIFFVLHLVYEELKLNTLMG 730 740 750 760 770 780 790 800 810 820 830 840 pF1KB9 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 EGICSLVELLVQLARDLKLGPYVDHYYRDYPTLVRTTGQVCTIDPGQTGFMHHPSFFTSE 790 800 810 820 830 840 850 860 870 880 890 900 pF1KB9 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PPSIYQWVSSCLKGEGMPPYPYLPGICERSRLVVLSIALYILGDESLVSDESSQYLTRIT 850 860 870 880 890 900 910 920 930 940 950 960 pF1KB9 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IAPQKLQVEQEENRFSFRHSTSVSSLAERLVVWMTNVGFTLRDLETLPFGIALPIRDAIY 910 920 930 940 950 960 970 980 990 1000 1010 pF1KB9 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKS----VLSSDVPSGTETEEEDDGM ::::::::::::::::::::::::::::::::::::: ::::::::::::::::::: XP_011 HCREQPASDWPEAVCLLIGRQDLSKQACEGNLPKGKSSVTQVLSSDVPSGTETEEEDDGM 970 980 990 1000 1010 1020 1020 1030 1040 1050 1060 1070 pF1KB9 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRLLQLCQR ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NDMNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSDHEFIEEKENRPQKWYF 1030 1040 1050 1060 1070 1080 1090 1100 1110 1120 1130 pF1KB9 TMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTVDLNSGNIDVPPNMTSWAS 1944 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:11:17 2016 done: Thu Nov 3 23:11:20 2016 Total Scan time: 22.010 Total Display time: 1.500 Function used was FASTA [36.3.4 Apr, 2011]