FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9376, 411 aa 1>>>pF1KB9376 411 - 411 aa - 411 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1621+/-0.00105; mu= 12.2953+/- 0.063 mean_var=69.4505+/-13.633, 0's: 0 Z-trim(103.7): 19 B-trim: 0 in 0/51 Lambda= 0.153899 statistics sampled from 7527 (7537) to 7527 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.596), E-opt: 0.2 (0.232), width: 16 Scan time: 2.520 The best scores are: opt bits E(32554) CCDS48159.1 LAMP2 gene_id:3920|Hs108|chrX ( 411) 2689 606.4 1.6e-173 CCDS14600.1 LAMP2 gene_id:3920|Hs108|chrX ( 410) 2564 578.6 3.6e-165 CCDS14599.1 LAMP2 gene_id:3920|Hs108|chrX ( 410) 2547 574.9 4.9e-164 CCDS41909.1 LAMP1 gene_id:3916|Hs108|chr13 ( 417) 877 204.1 2.1e-52 CCDS3242.1 LAMP3 gene_id:27074|Hs108|chr3 ( 416) 361 89.5 6.4e-18 >>CCDS48159.1 LAMP2 gene_id:3920|Hs108|chrX (411 aa) initn: 2689 init1: 2689 opt: 2689 Z-score: 3228.8 bits: 606.4 E(32554): 1.6e-173 Smith-Waterman score: 2689; 100.0% identity (100.0% similar) in 411 aa overlap (1-411:1-411) 10 20 30 40 50 60 pF1KB9 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS48 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV 370 380 390 400 410 >>CCDS14600.1 LAMP2 gene_id:3920|Hs108|chrX (410 aa) initn: 2585 init1: 2438 opt: 2564 Z-score: 3078.8 bits: 578.6 E(32554): 3.6e-165 Smith-Waterman score: 2564; 95.1% identity (98.5% similar) in 411 aa overlap (1-411:1-410) 10 20 30 40 50 60 pF1KB9 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV :::::.::: :.: ..:::. ::..:. ::::. :.:.:::::: .:::.. CCDS14 KYSTAQECSLDDD-TILIPIIVGAGLSGLIIVIVIAYVIGRRKSYAGYQTL 370 380 390 400 410 >>CCDS14599.1 LAMP2 gene_id:3920|Hs108|chrX (410 aa) initn: 2545 init1: 2441 opt: 2547 Z-score: 3058.4 bits: 574.9 E(32554): 4.9e-164 Smith-Waterman score: 2547; 94.4% identity (99.0% similar) in 409 aa overlap (1-409:1-408) 10 20 30 40 50 60 pF1KB9 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 MVCFRLFPVPGSGLVLVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNKT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 YKTVTISDHGTVTYNGSICGDDQNGPKIAVQFGPGFSWIANFTKAASTYSIDSVSFSYNT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 GDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 TVSTNEFLCDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 LNITQDKVASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS14 ISMYLVNGSVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQG 310 320 330 340 350 360 370 380 390 400 410 pF1KB9 KYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV :::::..::::.: :::.:.:::.::. ..:.:...:.:: .. ..::. CCDS14 KYSTAQDCSADDD-NFLVPIAVGAALAGVLILVLLAYFIGLKHHHAGYEQF 370 380 390 400 410 >>CCDS41909.1 LAMP1 gene_id:3916|Hs108|chr13 (417 aa) initn: 776 init1: 289 opt: 877 Z-score: 1054.4 bits: 204.1 E(32554): 2.1e-52 Smith-Waterman score: 877; 36.0% identity (68.3% similar) in 419 aa overlap (10-411:4-417) 10 20 30 40 50 pF1KB9 MVCFRLFPVPGSG-----LVLVCLVLGAVRSYALELNLTDSENAT-CLYAKWQMNFTVRY :::. :.:. :.:: .. . . .. . :.: :..:... :.: : CCDS41 MAAPGSARRPLLLLLLLLLLGLMHCASAAMFMVKNGNGTACIMANFSAAFSVNY 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 ET-TNKTYKTVTISDHGTVTYNGSICG-DDQNGPKIAVQFGPGFSWIANFTKAASTYSID .: .. : . . .::. : : :: .. . :.... :: : . :::. :. ::.. CCDS41 DTKSGPKNMTFDLPSDATVVLNRSSCGKENTSDPSLVIAFGRGHTLTLNFTRNATRYSVQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 SVSFSYNTGDNTTFPDAEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVL .:: :: .:. ::.: .: : ::. . :: .. .:: : . .. :.:. :. CCDS41 LMSFVYNLSDTHLFPNASSKEIKTVESITDIRADIDKKYRCVSGTQVHMNNVTVTLHDAT 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 VQAFVQNGTVSTNEFLCDKDKTS-TVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDT .::...:.. : .: :..:. : :.:: . :::. .:.:: .: . :.:.. : : CCDS41 IQAYLSNSSFSRGETRCEQDRPSPTTAPP---APPSPSPSPVPK-SPSVDKYNVSGTNGT 180 190 200 210 220 230 240 250 260 270 280 pF1KB9 CLLATMGLQLNITQDK-----VASVININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVF ::::.::::::.: .. :. ..::::: : ..::: .: . :.:.: : : : CCDS41 CLLASMGLQLNLTYERKDNTTVTRLLNINPNKTSASGSCGAHLVTLELHSEGTTVLLFQF 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB9 AVK-NENRFYLKEVNISMYLVNGS--VFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAF ... . .::.:. .... : .. .:. ::..: .: .:.:: :: :. : :. :: CCDS41 GMNASSSRFFLQGIQLNTILPDARDPAFKAANGSLRALQATVGNSYKCNAEEHVRVTKAF 300 310 320 330 340 350 350 360 370 380 390 400 pF1KB9 QINTFDLRVQPFNVTQGKYSTAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRK ..: : . :: :.: :.....::: : . ..:::.::: ::. :...:.:.:..::.. CCDS41 SVNIFKVWVQAFKVEGGQFGSVEECLLDEN-SMLIPIAVGGALAGLVLIVLIAYLVGRKR 360 370 380 390 400 410 pF1KB9 SRTGYQSV :..:::.. CCDS41 SHAGYQTI 410 >>CCDS3242.1 LAMP3 gene_id:27074|Hs108|chr3 (416 aa) initn: 199 init1: 76 opt: 361 Z-score: 435.2 bits: 89.5 E(32554): 6.4e-18 Smith-Waterman score: 374; 28.0% identity (60.4% similar) in 379 aa overlap (46-411:75-416) 20 30 40 50 60 70 pF1KB9 LVCLVLGAVRSYALELNLTDSENATCLYAKWQMNFTVRYETTNK--TYKTVTISD--HGT .: ::. ::. : .:.: : . CCDS32 VQDIKKPVQQPAKQAPHQTLAARFMDGHITFQTAATVKIPTTTPATTKNTATTSPITYTL 50 60 70 80 90 100 80 90 100 110 120 pF1KB9 VTYNGSICGDDQNGPKIAVQFGPG---FSWIANFTKAASTYSIDSVSFSYNTGDNTTFPD :: ... .. : : ::. .: ..: : : . .: . :..:: ::: :. CCDS32 VTTQATPNNSHTAPPVTEVTVGPSLAPYSLPPTITPPAHTTGTSSSTVSHTTG-NTTQPS 110 120 130 140 150 160 130 140 150 160 170 180 pF1KB9 AEDKGILTVDELLAIRIPLNDLFRCNSLSTLEKNDVVQHYWDVLVQAFVQNGTVSTNEFL . :. :.: .:.:. . :. :: ::... . CCDS32 NQT----TLPATLSI--------------ALHKSTTGQKP----VQPTHAPGTTAAAH-- 170 180 190 190 200 210 220 230 240 pF1KB9 CDKDKTSTVAPTIHTTVPSPTTTPTPKEKPEAGTYSVNNGNDTCLLATMGLQLNITQDK- . : :.::. .:::.:: .: :. . ..: :.: ::. :. : ::.:: :.::: CCDS32 ---NTTRTAAPA--STVPGPTLAPQPS-SVKTGIYQVLNGSRLCIKAEMGIQL-IVQDKE 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB9 -VAS---VININPNTTHSTGSCRSHTALLRLNSSTIKYLDFVFAVKNENRFYLKEVNISM : : .::.::.:...:.: .. . : :: . .....:. :.:. .:..::. . CCDS32 SVFSPRRYFNIDPNATQASGNCGTRKSNLLLNFQG-GFVNLTFT-KDEESYYISEVGAYL 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB9 YLVNG-SVFSIANNNLSYWDAPLGSSYMCNKEQTVSVSGAFQINTFDLRVQPFNVTQGKY . . .... .. . .... .: :. : .::....:. .:..: :...: :. . .. CCDS32 TVSDPETIYQGIKHAVVMFQTAVGHSFKCVSEQSLQLSAHLQVKTTDVQLQAFDFEDDHF 320 330 340 350 360 370 370 380 390 400 410 pF1KB9 STAEECSADSDLNFLIPVAVGVALGFLIIVVFISYMIGRRKSRTGYQSV ....::: :: ....:: ....:. .. . . : : : . .::: . CCDS32 GNVDECS--SDYTIVLPVIGAIVVGLCLMGMGV-YKIRLRCQSSGYQRI 380 390 400 410 411 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 13:17:44 2016 done: Sat Nov 5 13:17:44 2016 Total Scan time: 2.520 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]