FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9409, 289 aa 1>>>pF1KB9409 289 - 289 aa - 289 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1677+/-0.000352; mu= 15.8923+/- 0.022 mean_var=64.1065+/-13.165, 0's: 0 Z-trim(113.7): 56 B-trim: 1871 in 2/50 Lambda= 0.160186 statistics sampled from 23167 (23229) to 23167 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.272), width: 16 Scan time: 7.460 The best scores are: opt bits E(85289) NP_001750 (OMIM: 123833,615938) G1/S-specific cycl ( 289) 1928 454.2 1.4e-127 NP_444284 (OMIM: 168461,193300,254500) G1/S-specif ( 295) 1190 283.6 3e-76 NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 i ( 292) 1174 279.9 3.9e-75 NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D ( 242) 923 221.9 9.6e-58 XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specif ( 276) 862 207.8 1.9e-53 NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D ( 211) 819 197.8 1.5e-50 NP_001129597 (OMIM: 123834) G1/S-specific cyclin-D ( 220) 548 135.2 1.1e-31 XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specif ( 195) 507 125.7 7e-29 XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 303 78.7 2.1e-14 XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 303 78.7 2.1e-14 NP_001104516 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 303 78.7 2.1e-14 XP_011533598 (OMIM: 604036) PREDICTED: cyclin-A1 i ( 421) 303 78.7 2.1e-14 NP_001104517 (OMIM: 604036) cyclin-A1 isoform c [H ( 421) 303 78.7 2.1e-14 NP_001104515 (OMIM: 604036) cyclin-A1 isoform b [H ( 464) 303 78.8 2.2e-14 NP_003905 (OMIM: 604036) cyclin-A1 isoform a [Homo ( 465) 303 78.8 2.2e-14 XP_011515668 (OMIM: 603775) PREDICTED: G1/S-specif ( 288) 294 76.6 6.4e-14 NP_001274363 (OMIM: 123834) G1/S-specific cyclin-D ( 96) 288 74.9 6.7e-14 NP_001129598 (OMIM: 123834) G1/S-specific cyclin-D ( 96) 288 74.9 6.7e-14 XP_016869448 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 295 76.9 7.2e-14 NP_477097 (OMIM: 603775) G1/S-specific cyclin-E2 [ ( 404) 295 76.9 7.2e-14 XP_016869447 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 295 76.9 7.2e-14 XP_016869446 (OMIM: 603775) PREDICTED: G1/S-specif ( 404) 295 76.9 7.2e-14 NP_001228 (OMIM: 123835) cyclin-A2 [Homo sapiens] ( 432) 293 76.4 1e-13 NP_001309191 (OMIM: 123837) G1/S-specific cyclin-E ( 395) 271 71.3 3.3e-12 XP_011525742 (OMIM: 123837) PREDICTED: G1/S-specif ( 407) 271 71.3 3.4e-12 NP_001229 (OMIM: 123837) G1/S-specific cyclin-E1 i ( 410) 271 71.3 3.4e-12 NP_114172 (OMIM: 123836) G2/mitotic-specific cycli ( 433) 244 65.1 2.7e-10 NP_001309188 (OMIM: 123837) G1/S-specific cyclin-E ( 365) 231 62.1 1.9e-09 NP_004692 (OMIM: 602755) G2/mitotic-specific cycli ( 398) 231 62.1 2e-09 NP_001752 (OMIM: 600227) cyclin-F isoform 1 [Homo ( 786) 212 57.9 7.4e-08 XP_016879311 (OMIM: 600227) PREDICTED: cyclin-F is ( 867) 212 57.9 8e-08 NP_066970 (OMIM: 607752,615872) cyclin-O [Homo sap ( 350) 202 55.3 1.9e-07 NP_001310467 (OMIM: 600227) cyclin-F isoform 2 [Ho ( 478) 196 54.0 6.4e-07 NP_954854 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 190 52.5 1.1e-06 NP_004051 (OMIM: 601578) cyclin-G1 [Homo sapiens] ( 295) 190 52.5 1.1e-06 NP_004345 (OMIM: 603203) cyclin-G2 [Homo sapiens] ( 344) 163 46.3 9.6e-05 XP_011530700 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 163 46.3 9.6e-05 XP_011530701 (OMIM: 603203) PREDICTED: cyclin-G2 i ( 344) 163 46.3 9.6e-05 NP_149020 (OMIM: 300456) G2/mitotic-specific cycli (1395) 169 48.1 0.00012 XP_016885407 (OMIM: 300456) PREDICTED: G2/mitotic- (1395) 169 48.1 0.00012 XP_016885406 (OMIM: 300456) PREDICTED: G2/mitotic- (1396) 169 48.1 0.00012 XP_016885405 (OMIM: 300456) PREDICTED: G2/mitotic- (1403) 169 48.1 0.00012 XP_016885402 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 169 48.1 0.00012 XP_016885403 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 169 48.1 0.00012 XP_016885404 (OMIM: 300456) PREDICTED: G2/mitotic- (1404) 169 48.1 0.00012 NP_001186118 (OMIM: 601953) cyclin-H isoform 2 [Ho ( 270) 133 39.3 0.0096 XP_016865503 (OMIM: 601953) PREDICTED: cyclin-H is ( 272) 133 39.3 0.0096 XP_005248686 (OMIM: 601953) PREDICTED: cyclin-H is ( 276) 133 39.3 0.0097 >>NP_001750 (OMIM: 123833,615938) G1/S-specific cyclin-D (289 aa) initn: 1928 init1: 1928 opt: 1928 Z-score: 2411.7 bits: 454.2 E(85289): 1.4e-127 Smith-Waterman score: 1928; 100.0% identity (100.0% similar) in 289 aa overlap (1-289:1-289) 10 20 30 40 50 60 pF1KB9 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLTA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRKH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTDV 190 200 210 220 230 240 250 260 270 280 pF1KB9 DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL 250 260 270 280 >>NP_444284 (OMIM: 168461,193300,254500) G1/S-specific c (295 aa) initn: 1176 init1: 1059 opt: 1190 Z-score: 1489.9 bits: 283.6 E(85289): 3e-76 Smith-Waterman score: 1190; 61.8% identity (81.9% similar) in 293 aa overlap (2-289:4-295) 10 20 30 40 50 pF1KB9 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRM .::: ::. .::: : ::: .::::. .: :: :. ::::::::.. : ::.. NP_444 MEHQLLCCEVETIRRAYPDANLL-NDRVLRAMLKAEETCAPSVSYFKCVQKEVLPSMRKI 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPL ::::::::::::::::::::::::::::::. :. ::.::::::.:::.:::.::: :: NP_444 VATWMLEVCEEQKCEEEVFPLAMNYLDRFLSLEPVKKSRLQLLGATCMFVASKMKETIPL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 TAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIR :::::::::::::.:.:::. ::....::::::::.::::::::.: :.:. .:. ..:: NP_444 TAEKLCIYTDNSIRPEELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPEAEENKQIIR 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 KHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNT ::::::.:::::: :: ::::.:.::: ::. ::. . :. ::..:... . NP_444 KHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLNLRSPNNFLSYYRLTRFLSRVIKC 180 190 200 210 220 230 240 250 260 270 280 pF1KB9 DVDCLKACQEQIEAVLLNSLQQYRQDQ-----RDGSKSEDELDQASTPTDVRDIDL : :::.::::::::.: .::.: .:.. .. . :.:.: : :::::::.:. NP_444 DPDCLRACQEQIEALLESSLRQAQQNMDPKAAEEEEEEEEEVDLACTPTDVRDVDI 240 250 260 270 280 290 >>NP_001751 (OMIM: 123834) G1/S-specific cyclin-D3 isofo (292 aa) initn: 1171 init1: 977 opt: 1174 Z-score: 1469.9 bits: 279.9 E(85289): 3.9e-75 Smith-Waterman score: 1174; 61.6% identity (81.8% similar) in 297 aa overlap (1-289:1-292) 10 20 30 40 50 pF1KB9 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV ::::: : . . :: : :: :.::::.:: .::::.:. :::.:::..:.:.::.:. NP_001 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT : :::::::::.:::::::::::::::.:. ::: :..:::::::::.:::::.::.::: NP_001 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK ::::::::....:..: .::..:::::::.:::: :::. ::..: :.. .:..: NP_001 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD :::::.::::::. :::::::::::::.:::. :: . :.. : :::::: ::.:. NP_001 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG----ACSMSGDELTELLAGITGTE 190 200 210 220 230 240 250 260 270 280 pF1KB9 VDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL ::::.::::::::.: .::.. : . . ::.:. .:.:::::: : : NP_001 VDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 240 250 260 270 280 290 >>NP_001274356 (OMIM: 123834) G1/S-specific cyclin-D3 is (242 aa) initn: 915 init1: 746 opt: 923 Z-score: 1157.7 bits: 221.9 E(85289): 9.6e-58 Smith-Waterman score: 923; 62.3% identity (82.3% similar) in 231 aa overlap (66-289:17-242) 40 50 60 70 80 90 pF1KB9 RYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPK :::::.:::::::::::::::.:. ::: : NP_001 MKSAGGSGRSLLPSPRVCEEQRCEEEVFPLAMNYLDRYLSCVPTRK 10 20 30 40 100 110 120 130 140 150 pF1KB9 SHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVT ..:::::::::.:::::.::.::: ::::::::....:..: .::..:::::::.:::: NP_001 AQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVI 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB9 PHDFIEHILRKLPQQREKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQ :::. ::..: :.. .:..::::::.::::::. :::::::::::::.:::. :: NP_001 AHDFLAFILHRLSLPRDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG 110 120 130 140 150 160 220 230 240 250 260 pF1KB9 QDEEVSSLTCDALTELLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRD-------G . :.. : :::::: ::.:.::::.::::::::.: .::.. : . . : NP_001 ----ACSMSGDELTELLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRG 170 180 190 200 210 220 270 280 pF1KB9 SKSEDELDQASTPTDVRDIDL :.:. .:.:::::: : : NP_001 SSSQGP-SQTSTPTDVTAIHL 230 240 >>XP_011513273 (OMIM: 123834) PREDICTED: G1/S-specific c (276 aa) initn: 867 init1: 842 opt: 862 Z-score: 1080.6 bits: 207.8 E(85289): 1.9e-53 Smith-Waterman score: 862; 65.4% identity (86.9% similar) in 191 aa overlap (1-190:1-191) 10 20 30 40 50 pF1KB9 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV ::::: : . . :: : :: :.::::.:: .::::.:. :::.:::..:.:.::.:. XP_011 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT : :::::::::.:::::::::::::::.:. ::: :..:::::::::.:::::.::.::: XP_011 AYWMLEVCEEQRCEEEVFPLAMNYLDRYLSCVPTRKAQLQLLGAVCMLLASKLRETTPLT 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK ::::::::....:..: .::..:::::::.:::: :::. ::..: :.. .:..: XP_011 IEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB9 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD :::::.::::: XP_011 HAQTFLALCATGLPAGLSGADRSCTQGEPQGSLSDQLQPSAQSPPGLQQPRAQPDQHSYR 190 200 210 220 230 240 >>NP_001129489 (OMIM: 123834) G1/S-specific cyclin-D3 is (211 aa) initn: 811 init1: 642 opt: 819 Z-score: 1028.6 bits: 197.8 E(85289): 1.5e-50 Smith-Waterman score: 819; 60.2% identity (81.0% similar) in 216 aa overlap (81-289:1-211) 60 70 80 90 100 110 pF1KB9 IQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLAS ::::::.:. ::: :..:::::::::.::: NP_001 MNYLDRYLSCVPTRKAQLQLLGAVCMLLAS 10 20 30 120 130 140 150 160 170 pF1KB9 KLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQ ::.::.::: ::::::::....:..: .::..:::::::.:::: :::. ::..: NP_001 KLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB9 REKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTE :.. .:..::::::.::::::. :::::::::::::.:::. :: . :.. : ::: NP_001 RDRQALVKKHAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG----ACSMSGDELTE 100 110 120 130 140 240 250 260 270 280 pF1KB9 LLAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTD ::: ::.:.::::.::::::::.: .::.. : . . ::.:. .:.::::: NP_001 LLAGITGTEVDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTD 150 160 170 180 190 200 pF1KB9 VRDIDL : : : NP_001 VTAIHL 210 >>NP_001129597 (OMIM: 123834) G1/S-specific cyclin-D3 is (220 aa) initn: 565 init1: 371 opt: 548 Z-score: 689.9 bits: 135.2 E(85289): 1.1e-31 Smith-Waterman score: 643; 43.4% identity (58.9% similar) in 297 aa overlap (1-289:1-220) 10 20 30 40 50 pF1KB9 MELLCHE-VDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMV ::::: : . . :: : :: :.::::.:: .::::.:. :::.:::..:.:.::.:. NP_001 MELLCCEGTRHAPRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKML 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 ATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLKETSPLT : :::: NP_001 AYWMLE------------------------------------------------------ 120 130 140 150 160 170 pF1KB9 AEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREKLSLIRK .::..:::::::.:::: :::. ::..: :.. .:..: NP_001 ------------------DWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKK 70 80 90 100 180 190 200 210 220 230 pF1KB9 HAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTELLAKITNTD :::::.::::::. :::::::::::::.:::. :: . :.. : :::::: ::.:. NP_001 HAQTFLALCATDYTFAMYPPSMIATGSIGAAVQGLG----ACSMSGDELTELLAGITGTE 110 120 130 140 150 160 240 250 260 270 280 pF1KB9 VDCLKACQEQIEAVLLNSLQQYRQDQRD-------GSKSEDELDQASTPTDVRDIDL ::::.::::::::.: .::.. : . . ::.:. .:.:::::: : : NP_001 VDCLRACQEQIEAALRESLREASQTSSSPAPKAPRGSSSQGP-SQTSTPTDVTAIHL 170 180 190 200 210 220 >>XP_011513274 (OMIM: 123834) PREDICTED: G1/S-specific c (195 aa) initn: 507 init1: 507 opt: 507 Z-score: 639.5 bits: 125.7 E(85289): 7e-29 Smith-Waterman score: 507; 65.5% identity (89.1% similar) in 110 aa overlap (81-190:1-110) 60 70 80 90 100 110 pF1KB9 IQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLAS ::::::.:. ::: :..:::::::::.::: XP_011 MNYLDRYLSCVPTRKAQLQLLGAVCMLLAS 10 20 30 120 130 140 150 160 170 pF1KB9 KLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQ ::.::.::: ::::::::....:..: .::..:::::::.:::: :::. ::..: XP_011 KLRETTPLTIEKLCIYTDHAVSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB9 REKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDALTE :.. .:..::::::.::::: XP_011 RDRQALVKKHAQTFLALCATGLPAGLSGADRSCTQGEPQGSLSDQLQPSAQSPPGLQQPR 100 110 120 130 140 150 >>XP_011533597 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa) initn: 251 init1: 251 opt: 303 Z-score: 379.7 bits: 78.7 E(85289): 2.1e-14 Smith-Waterman score: 309; 29.1% identity (59.4% similar) in 254 aa overlap (24-275:169-407) 10 20 30 40 50 pF1KB9 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQP ... : : : :. :. :.: : :: XP_011 SPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKK-QPDITE 140 150 160 170 180 190 60 70 80 90 100 110 pF1KB9 YMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLK :: ... :..:: :: : . :.. ::.:.:::::. . . ...:::.:.. :.:::: . XP_011 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYE 200 210 220 230 240 250 120 130 140 150 160 170 pF1KB9 ETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREK : : .... ::.. ..::. : ..: : ..:.. : ..:. . ::. . XP_011 EIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT 260 270 280 290 300 310 180 190 200 210 220 230 pF1KB9 LSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDA--LTEL .: . :. ..: .: : : ::.::. ::.: ... : . : XP_011 ENLAKYVAE--LSLLEAD-PFLKYLPSLIAA----AAFC-------LANYTVNKHFWPET 320 330 340 350 360 240 250 260 270 280 pF1KB9 LAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL :: .:. ... . : ... . :. .. .: :. :. : XP_011 LAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 370 380 390 400 410 420 >>XP_011533596 (OMIM: 604036) PREDICTED: cyclin-A1 isofo (421 aa) initn: 251 init1: 251 opt: 303 Z-score: 379.7 bits: 78.7 E(85289): 2.1e-14 Smith-Waterman score: 309; 29.1% identity (59.4% similar) in 254 aa overlap (24-275:169-407) 10 20 30 40 50 pF1KB9 MELLCHEVDPVRRAVRDRNLLRDDRVLQNLLTIEERYLPQCSYFKCVQKDIQP ... : : : :. :. :.: : :: XP_011 SPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKK-QPDITE 140 150 160 170 180 190 60 70 80 90 100 110 pF1KB9 YMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKSHLQLLGAVCMFLASKLK :: ... :..:: :: : . :.. ::.:.:::::. . . ...:::.:.. :.:::: . XP_011 GMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYE 200 210 220 230 240 250 120 130 140 150 160 170 pF1KB9 ETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQREK : : .... ::.. ..::. : ..: : ..:.. : ..:. . ::. . XP_011 EIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRT 260 270 280 290 300 310 180 190 200 210 220 230 pF1KB9 LSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVSSLTCDA--LTEL .: . :. ..: .: : : ::.::. ::.: ... : . : XP_011 ENLAKYVAE--LSLLEAD-PFLKYLPSLIAA----AAFC-------LANYTVNKHFWPET 320 330 340 350 360 240 250 260 270 280 pF1KB9 LAKITNTDVDCLKACQEQIEAVLLNSLQQYRQDQRDGSKSEDELDQASTPTDVRDIDL :: .:. ... . : ... . :. .. .: :. :. : XP_011 LAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ 370 380 390 400 410 420 289 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 18:25:11 2016 done: Thu Nov 3 18:25:12 2016 Total Scan time: 7.460 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]