FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9414, 713 aa 1>>>pF1KB9414 713 - 713 aa - 713 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 9.5488+/-0.00036; mu= 2.8918+/- 0.023 mean_var=269.8781+/-56.254, 0's: 0 Z-trim(122.4): 12 B-trim: 524 in 1/55 Lambda= 0.078071 statistics sampled from 40410 (40423) to 40410 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.474), width: 16 Scan time: 12.940 The best scores are: opt bits E(85289) NP_001177779 (OMIM: 604911) CCR4-NOT transcription ( 713) 4901 565.5 2.6e-160 XP_016867724 (OMIM: 604911) PREDICTED: CCR4-NOT tr ( 713) 4901 565.5 2.6e-160 NP_001177778 (OMIM: 604911) CCR4-NOT transcription ( 710) 4859 560.8 6.8e-159 NP_001177776 (OMIM: 604911) CCR4-NOT transcription ( 642) 3773 438.4 4.2e-122 NP_037448 (OMIM: 604911) CCR4-NOT transcription co ( 639) 3731 433.7 1.1e-120 NP_001177777 (OMIM: 604911) CCR4-NOT transcription ( 575) 3708 431.0 6.1e-120 NP_001008226 (OMIM: 604911) CCR4-NOT transcription ( 572) 3666 426.3 1.6e-118 >>NP_001177779 (OMIM: 604911) CCR4-NOT transcription com (713 aa) initn: 4901 init1: 4901 opt: 4901 Z-score: 2999.2 bits: 565.5 E(85289): 2.6e-160 Smith-Waterman score: 4901; 100.0% identity (100.0% similar) in 713 aa overlap (1-713:1-713) 10 20 30 40 50 60 pF1KB9 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH 670 680 690 700 710 >>XP_016867724 (OMIM: 604911) PREDICTED: CCR4-NOT transc (713 aa) initn: 4901 init1: 4901 opt: 4901 Z-score: 2999.2 bits: 565.5 E(85289): 2.6e-160 Smith-Waterman score: 4901; 100.0% identity (100.0% similar) in 713 aa overlap (1-713:1-713) 10 20 30 40 50 60 pF1KB9 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF 610 620 630 640 650 660 670 680 690 700 710 pF1KB9 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH ::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH 670 680 690 700 710 >>NP_001177778 (OMIM: 604911) CCR4-NOT transcription com (710 aa) initn: 4861 init1: 3025 opt: 4859 Z-score: 2973.7 bits: 560.8 E(85289): 6.8e-159 Smith-Waterman score: 4859; 99.4% identity (99.6% similar) in 713 aa overlap (1-713:1-710) 10 20 30 40 50 60 pF1KB9 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP :::::::::::::::::::::::::::::: .:::::::::::::::::::::::::: NP_001 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQ---SPIDKPSDSLSIGNGDNSQQISNSDTP 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW 540 550 560 570 580 590 610 620 630 640 650 660 pF1KB9 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF 600 610 620 630 640 650 670 680 690 700 710 pF1KB9 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH 660 670 680 690 700 710 >>NP_001177776 (OMIM: 604911) CCR4-NOT transcription com (642 aa) initn: 3743 init1: 3743 opt: 3773 Z-score: 2313.2 bits: 438.4 E(85289): 4.2e-122 Smith-Waterman score: 4272; 90.0% identity (90.0% similar) in 713 aa overlap (1-713:1-642) 10 20 30 40 50 60 pF1KB9 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW :: NP_001 VA---------------------------------------------------------- 610 620 630 640 650 660 pF1KB9 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF ::::::::::::::::::::::::::::::::::::::::::::::: NP_001 -------------GIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF 550 560 570 580 670 680 690 700 710 pF1KB9 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH 590 600 610 620 630 640 >>NP_037448 (OMIM: 604911) CCR4-NOT transcription comple (639 aa) initn: 3701 init1: 1865 opt: 3731 Z-score: 2287.6 bits: 433.7 E(85289): 1.1e-120 Smith-Waterman score: 4230; 89.5% identity (89.6% similar) in 713 aa overlap (1-713:1-639) 10 20 30 40 50 60 pF1KB9 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP :::::::::::::::::::::::::::::: .:::::::::::::::::::::::::: NP_037 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQ---SPIDKPSDSLSIGNGDNSQQISNSDTP 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW :: NP_037 VA---------------------------------------------------------- 610 620 630 640 650 660 pF1KB9 DSPGSWTDPAIITGIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF ::::::::::::::::::::::::::::::::::::::::::::::: NP_037 -------------GIPASSGNSLDSLQDDNPPHWLKSLQALTEMDGPSAAPSQTHHSAPF 540 550 560 570 580 670 680 690 700 710 pF1KB9 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 STQIPLHRASWNPYPPPSNPSSFHSPPPGFQTAFRPPSKTPTDLLQSSTLDRH 590 600 610 620 630 >>NP_001177777 (OMIM: 604911) CCR4-NOT transcription com (575 aa) initn: 3708 init1: 3708 opt: 3708 Z-score: 2274.3 bits: 431.0 E(85289): 6.1e-120 Smith-Waterman score: 3708; 100.0% identity (100.0% similar) in 542 aa overlap (1-542:1-542) 10 20 30 40 50 60 pF1KB9 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW :: NP_001 VAGEEEVKVSTMPLSTSSHSLQQGQQPTSLHTTVA 550 560 570 >>NP_001008226 (OMIM: 604911) CCR4-NOT transcription com (572 aa) initn: 3668 init1: 1850 opt: 3666 Z-score: 2248.7 bits: 426.3 E(85289): 1.6e-118 Smith-Waterman score: 3666; 99.3% identity (99.4% similar) in 542 aa overlap (1-542:1-539) 10 20 30 40 50 60 pF1KB9 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSRSPDAKEDPVECPLCMEPLEIDDINFFPCTCGYQICRFCWHRIRTDENGLCPACRKPY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PEDPAVYKPLSQEELQRIKNEKKQKQNERKQKISENRKHLASVRVVQKNLVFVVGLSQRL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ADPEVLKRPEYFGKFGKIHKVVINNSTSYAGSQGPSASAYVTYIRSEDALRAIQCVNNVV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VDGRTLKASLGTTKYCSYFLKNMQCPKPDCMYLHELGDEAASFTKEEMQAGKHQEYEQKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQRYDTPIDKPSDSLSIGNGDNSQQISNSDTP :::::::::::::::::::::::::::::: .:::::::::::::::::::::::::: NP_001 LQELYKLNPNFLQLSTGSVDKNKNKVTPLQ---SPIDKPSDSLSIGNGDNSQQISNSDTP 250 260 270 280 290 310 320 330 340 350 360 pF1KB9 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPPPGLSKSNPVIPISSSNHSARSPFEGAVTESQSLFSDNFRHPNPIPSGLPPFPSSPQT 300 310 320 330 340 350 370 380 390 400 410 420 pF1KB9 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSDWPTAPEPQSLFTSETIPVSSSTDWQAAFGFGSSKQPEDDLGFDPFDVTRKALADLIE 360 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KELSVQDQPSLSPTSLQNSSSHTTTAKGPGSGFLHPAAATNANSLNSTFSVLPQRFPQFQ 420 430 440 450 460 470 490 500 510 520 530 540 pF1KB9 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QHRAVYNSFSFPGQAARYPWMAFPRNSIMHLNHTANPTSNSNFLDLNLPPQHNTGLGGIP 480 490 500 510 520 530 550 560 570 580 590 600 pF1KB9 VADNSSSVESLNMKEWQDGLRALLPNININFGGLPNSSSPSNANHSAPTSNTATTDSLSW :: NP_001 VAGEEEVKVSTMPLSTSSHSLQQGQQPTSLHTTVA 540 550 560 570 713 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:14:14 2016 done: Thu Nov 3 23:14:15 2016 Total Scan time: 12.940 Total Display time: 0.110 Function used was FASTA [36.3.4 Apr, 2011]