FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9422, 571 aa 1>>>pF1KB9422 571 - 571 aa - 571 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.8479+/-0.000582; mu= -11.5254+/- 0.036 mean_var=492.0398+/-102.595, 0's: 0 Z-trim(118.1): 95 B-trim: 96 in 2/54 Lambda= 0.057819 statistics sampled from 30657 (30750) to 30657 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.361), width: 16 Scan time: 9.810 The best scores are: opt bits E(85289) NP_001008213 (OMIM: 137760,602432,606657,613435) o ( 577) 3596 315.3 3.5e-85 NP_001008212 (OMIM: 137760,602432,606657,613435) o ( 577) 3596 315.3 3.5e-85 NP_001008214 (OMIM: 137760,602432,606657,613435) o ( 577) 3596 315.3 3.5e-85 NP_068815 (OMIM: 137760,602432,606657,613435) opti ( 577) 3596 315.3 3.5e-85 NP_001308325 (OMIM: 300248,300291,300301,300584,30 ( 419) 495 56.5 2.1e-07 NP_003630 (OMIM: 300248,300291,300301,300584,30063 ( 419) 495 56.5 2.1e-07 NP_001093327 (OMIM: 300248,300291,300301,300584,30 ( 419) 495 56.5 2.1e-07 NP_001093326 (OMIM: 300248,300291,300301,300584,30 ( 487) 495 56.5 2.3e-07 NP_001308326 (OMIM: 300248,300291,300301,300584,30 ( 418) 493 56.3 2.3e-07 >>NP_001008213 (OMIM: 137760,602432,606657,613435) optin (577 aa) initn: 2279 init1: 2279 opt: 3596 Z-score: 1650.3 bits: 315.3 E(85289): 3.5e-85 Smith-Waterman score: 3596; 99.0% identity (99.0% similar) in 577 aa overlap (1-571:1-577) 10 20 30 40 50 60 pF1KB9 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IRMAEGEAEGSVKEIKHSPGPTRTVSTGT------SRSADGAKNYFEHEELTVSQLLLCL ::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 IRMAEGEAEGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNYFEHEELTVSQLLLCL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE 490 500 510 520 530 540 540 550 560 570 pF1KB9 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII ::::::::::::::::::::::::::::::::::::: NP_001 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII 550 560 570 >>NP_001008212 (OMIM: 137760,602432,606657,613435) optin (577 aa) initn: 2279 init1: 2279 opt: 3596 Z-score: 1650.3 bits: 315.3 E(85289): 3.5e-85 Smith-Waterman score: 3596; 99.0% identity (99.0% similar) in 577 aa overlap (1-571:1-577) 10 20 30 40 50 60 pF1KB9 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IRMAEGEAEGSVKEIKHSPGPTRTVSTGT------SRSADGAKNYFEHEELTVSQLLLCL ::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 IRMAEGEAEGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNYFEHEELTVSQLLLCL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE 490 500 510 520 530 540 540 550 560 570 pF1KB9 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII ::::::::::::::::::::::::::::::::::::: NP_001 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII 550 560 570 >>NP_001008214 (OMIM: 137760,602432,606657,613435) optin (577 aa) initn: 2279 init1: 2279 opt: 3596 Z-score: 1650.3 bits: 315.3 E(85289): 3.5e-85 Smith-Waterman score: 3596; 99.0% identity (99.0% similar) in 577 aa overlap (1-571:1-577) 10 20 30 40 50 60 pF1KB9 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IRMAEGEAEGSVKEIKHSPGPTRTVSTGT------SRSADGAKNYFEHEELTVSQLLLCL ::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_001 IRMAEGEAEGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNYFEHEELTVSQLLLCL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE 490 500 510 520 530 540 540 550 560 570 pF1KB9 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII ::::::::::::::::::::::::::::::::::::: NP_001 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII 550 560 570 >>NP_068815 (OMIM: 137760,602432,606657,613435) optineur (577 aa) initn: 2279 init1: 2279 opt: 3596 Z-score: 1650.3 bits: 315.3 E(85289): 3.5e-85 Smith-Waterman score: 3596; 99.0% identity (99.0% similar) in 577 aa overlap (1-571:1-577) 10 20 30 40 50 60 pF1KB9 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 MSHQPLSCLTEKEDSPSESTGNGPPHLAHPNLDTFTPEELLQQMKELLTENHQLKEAMKL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 NNQAMKGRFEELSAWTEKQKEERQFFEIQSKEAKERLMALSHENEKLKEELGKLKGKSER 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 SSEDPTDDSRLPRAEAEQEKDQLRTQVVRLQAEKADLLGIVSELQLKLNSSGSSEDSFVE 130 140 150 160 170 180 190 200 210 220 230 pF1KB9 IRMAEGEAEGSVKEIKHSPGPTRTVSTGT------SRSADGAKNYFEHEELTVSQLLLCL ::::::::::::::::::::::::::::: ::::::::::::::::::::::::: NP_068 IRMAEGEAEGSVKEIKHSPGPTRTVSTGTALSKYRSRSADGAKNYFEHEELTVSQLLLCL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB9 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 REGNQKVERLEVALKEAKERVSDFEKKTSNRSEIETQTEGSTEKENDEEKGPETVGSEVE 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB9 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 ALNLQVTSLFKELQEAHTKLSEAELMKKRLQEKCQALERKNSAIPSELNEKQELVYTNKK 310 320 330 340 350 360 360 370 380 390 400 410 pF1KB9 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 LELQVESMLSEIKMEQAKTEDEKSKLTVLQMTHNKLLQEHNNALKTIEELTRKESEKVDR 370 380 390 400 410 420 420 430 440 450 460 470 pF1KB9 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 AVLKELSEKLELAEKALASKQLQMDEMKQTIAKQEEDLETMTILRAQMEVYCSDFHAERA 430 440 450 460 470 480 480 490 500 510 520 530 pF1KB9 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_068 AREKIHEEKEQLALQLAVLLKENDAFEDGGRQSLMEMQSRHGARTSDSDQQAYLVQRGAE 490 500 510 520 530 540 540 550 560 570 pF1KB9 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII ::::::::::::::::::::::::::::::::::::: NP_068 DRDWRQQRNIPIHSCPKCGEVLPDIDTLQIHVMDCII 550 560 570 >>NP_001308325 (OMIM: 300248,300291,300301,300584,300636 (419 aa) initn: 598 init1: 216 opt: 495 Z-score: 254.1 bits: 56.5 E(85289): 2.1e-07 Smith-Waterman score: 495; 30.4% identity (64.9% similar) in 345 aa overlap (236-570:83-418) 210 220 230 240 250 260 pF1KB9 STGTSRSADGAKNYFEHEELTVSQLLLCLREGNQKVER--LEVALKEAKERVSDFEKKTS ...:. :. : ..::.. : :. NP_001 RCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLV---ERLGL 60 70 80 90 100 270 280 290 300 310 320 pF1KB9 NRSEIETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKR .. ... : : . .. . .. . .. . ... :::::. ::::....: : . NP_001 EKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQA 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB9 LQEKCQALERKNSAIPSELN--EKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLT :. . .: .. . :: . ..:. : ... :..: .:. . ..::. . .:: ::. NP_001 LEGRARAASEQARQLESEREALQQQHSVQVDQ-LRMQGQSVEAALRMERQAASEEKRKLA 170 180 190 200 210 220 390 400 410 420 430 440 pF1KB9 VLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEM ::.....:.::..: .:. . ::. :..:...:. ::.::..:: .:.. NP_001 QLQVAYHQLFQEYDNHIKS----SVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKL 230 240 250 260 270 280 450 460 470 480 490 500 pF1KB9 KQTIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFE :. ... .::. .:.:: ..: .::.::: ::::. :.:: : :: : .: . .. NP_001 KEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLK 290 300 310 320 330 340 510 520 530 540 550 pF1KB9 DGGRQS--LMEMQSRHGARTSDSD---QQAYLVQRGAEDRDWRQQ-RNIPIHSCPKCGEV . ..: . .:..:: ...:.. ::: . : . :. .. : :::: NP_001 ASCQESARIEDMRKRH-VEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQ 350 360 370 380 390 400 560 570 pF1KB9 LPDIDTLQIHVMDCII ::.::::::::.:: NP_001 APDMDTLQIHVMECIE 410 >>NP_003630 (OMIM: 300248,300291,300301,300584,300636,30 (419 aa) initn: 598 init1: 216 opt: 495 Z-score: 254.1 bits: 56.5 E(85289): 2.1e-07 Smith-Waterman score: 495; 30.4% identity (64.9% similar) in 345 aa overlap (236-570:83-418) 210 220 230 240 250 260 pF1KB9 STGTSRSADGAKNYFEHEELTVSQLLLCLREGNQKVER--LEVALKEAKERVSDFEKKTS ...:. :. : ..::.. : :. NP_003 RCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLV---ERLGL 60 70 80 90 100 270 280 290 300 310 320 pF1KB9 NRSEIETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKR .. ... : : . .. . .. . .. . ... :::::. ::::....: : . NP_003 EKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQA 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB9 LQEKCQALERKNSAIPSELN--EKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLT :. . .: .. . :: . ..:. : ... :..: .:. . ..::. . .:: ::. NP_003 LEGRARAASEQARQLESEREALQQQHSVQVDQ-LRMQGQSVEAALRMERQAASEEKRKLA 170 180 190 200 210 220 390 400 410 420 430 440 pF1KB9 VLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEM ::.....:.::..: .:. . ::. :..:...:. ::.::..:: .:.. NP_003 QLQVAYHQLFQEYDNHIKS----SVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKL 230 240 250 260 270 280 450 460 470 480 490 500 pF1KB9 KQTIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFE :. ... .::. .:.:: ..: .::.::: ::::. :.:: : :: : .: . .. NP_003 KEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLK 290 300 310 320 330 340 510 520 530 540 550 pF1KB9 DGGRQS--LMEMQSRHGARTSDSD---QQAYLVQRGAEDRDWRQQ-RNIPIHSCPKCGEV . ..: . .:..:: ...:.. ::: . : . :. .. : :::: NP_003 ASCQESARIEDMRKRH-VEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQ 350 360 370 380 390 400 560 570 pF1KB9 LPDIDTLQIHVMDCII ::.::::::::.:: NP_003 APDMDTLQIHVMECIE 410 >>NP_001093327 (OMIM: 300248,300291,300301,300584,300636 (419 aa) initn: 598 init1: 216 opt: 495 Z-score: 254.1 bits: 56.5 E(85289): 2.1e-07 Smith-Waterman score: 495; 30.4% identity (64.9% similar) in 345 aa overlap (236-570:83-418) 210 220 230 240 250 260 pF1KB9 STGTSRSADGAKNYFEHEELTVSQLLLCLREGNQKVER--LEVALKEAKERVSDFEKKTS ...:. :. : ..::.. : :. NP_001 RCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLV---ERLGL 60 70 80 90 100 270 280 290 300 310 320 pF1KB9 NRSEIETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKR .. ... : : . .. . .. . .. . ... :::::. ::::....: : . NP_001 EKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQA 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB9 LQEKCQALERKNSAIPSELN--EKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLT :. . .: .. . :: . ..:. : ... :..: .:. . ..::. . .:: ::. NP_001 LEGRARAASEQARQLESEREALQQQHSVQVDQ-LRMQGQSVEAALRMERQAASEEKRKLA 170 180 190 200 210 220 390 400 410 420 430 440 pF1KB9 VLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEM ::.....:.::..: .:. . ::. :..:...:. ::.::..:: .:.. NP_001 QLQVAYHQLFQEYDNHIKS----SVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKL 230 240 250 260 270 280 450 460 470 480 490 500 pF1KB9 KQTIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFE :. ... .::. .:.:: ..: .::.::: ::::. :.:: : :: : .: . .. NP_001 KEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLK 290 300 310 320 330 340 510 520 530 540 550 pF1KB9 DGGRQS--LMEMQSRHGARTSDSD---QQAYLVQRGAEDRDWRQQ-RNIPIHSCPKCGEV . ..: . .:..:: ...:.. ::: . : . :. .. : :::: NP_001 ASCQESARIEDMRKRH-VEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQ 350 360 370 380 390 400 560 570 pF1KB9 LPDIDTLQIHVMDCII ::.::::::::.:: NP_001 APDMDTLQIHVMECIE 410 >>NP_001093326 (OMIM: 300248,300291,300301,300584,300636 (487 aa) initn: 598 init1: 216 opt: 495 Z-score: 253.3 bits: 56.5 E(85289): 2.3e-07 Smith-Waterman score: 495; 30.4% identity (64.9% similar) in 345 aa overlap (236-570:151-486) 210 220 230 240 250 260 pF1KB9 STGTSRSADGAKNYFEHEELTVSQLLLCLREGNQKVER--LEVALKEAKERVSDFEKKTS ...:. :. : ..::.. : :. NP_001 RCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLV---ERLGL 130 140 150 160 170 270 280 290 300 310 320 pF1KB9 NRSEIETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKR .. ... : : . .. . .. . .. . ... :::::. ::::....: : . NP_001 EKLDLKRQKEQALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQA 180 190 200 210 220 230 330 340 350 360 370 380 pF1KB9 LQEKCQALERKNSAIPSELN--EKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLT :. . .: .. . :: . ..:. : ... :..: .:. . ..::. . .:: ::. NP_001 LEGRARAASEQARQLESEREALQQQHSVQVDQ-LRMQGQSVEAALRMERQAASEEKRKLA 240 250 260 270 280 290 390 400 410 420 430 440 pF1KB9 VLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEM ::.....:.::..: .:. . ::. :..:...:. ::.::..:: .:.. NP_001 QLQVAYHQLFQEYDNHIKS----SVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKL 300 310 320 330 340 350 450 460 470 480 490 500 pF1KB9 KQTIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFE :. ... .::. .:.:: ..: .::.::: ::::. :.:: : :: : .: . .. NP_001 KEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLK 360 370 380 390 400 410 510 520 530 540 550 pF1KB9 DGGRQS--LMEMQSRHGARTSDSD---QQAYLVQRGAEDRDWRQQ-RNIPIHSCPKCGEV . ..: . .:..:: ...:.. ::: . : . :. .. : :::: NP_001 ASCQESARIEDMRKRH-VEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQ 420 430 440 450 460 470 560 570 pF1KB9 LPDIDTLQIHVMDCII ::.::::::::.:: NP_001 APDMDTLQIHVMECIE 480 >>NP_001308326 (OMIM: 300248,300291,300301,300584,300636 (418 aa) initn: 598 init1: 216 opt: 493 Z-score: 253.2 bits: 56.3 E(85289): 2.3e-07 Smith-Waterman score: 493; 31.0% identity (64.9% similar) in 345 aa overlap (236-570:83-417) 210 220 230 240 250 260 pF1KB9 STGTSRSADGAKNYFEHEELTVSQLLLCLREGNQKVER--LEVALKEAKERVSDFEKKTS ...:. :. : ..::.. : :. NP_001 RCLEENQELRDAIRQSNQILRERCEELLHFQASQREEKEFLMCKFQEARKLV---ERLGL 60 70 80 90 100 270 280 290 300 310 320 pF1KB9 NRSEIETQTEGSTEKENDEEKGPETVGSEVEALNLQVTSLFKELQEAHTKLSEAELMKKR .. ... : : . .: .. : . .. . ... :::::. ::::....: : . NP_001 EKLDLKRQKEQAL-REVEHLKRCQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQA 110 120 130 140 150 160 330 340 350 360 370 380 pF1KB9 LQEKCQALERKNSAIPSELN--EKQELVYTNKKLELQVESMLSEIKMEQAKTEDEKSKLT :. . .: .. . :: . ..:. : ... :..: .:. . ..::. . .:: ::. NP_001 LEGRARAASEQARQLESEREALQQQHSVQVDQ-LRMQGQSVEAALRMERQAASEEKRKLA 170 180 190 200 210 220 390 400 410 420 430 440 pF1KB9 VLQMTHNKLLQEHNNALKTIEELTRKESEKVDRAVLKELSEKLELAEKALASKQLQMDEM ::.....:.::..: .:. . ::. :..:...:. ::.::..:: .:.. NP_001 QLQVAYHQLFQEYDNHIKS----SVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKL 230 240 250 260 270 280 450 460 470 480 490 500 pF1KB9 KQTIAKQEEDLETMTILRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENDAFE :. ... .::. .:.:: ..: .::.::: ::::. :.:: : :: : .: . .. NP_001 KEEAEQHKIVMETVPVLKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLK 290 300 310 320 330 340 510 520 530 540 550 pF1KB9 DGGRQS--LMEMQSRHGARTSDSD---QQAYLVQRGAEDRDWRQQ-RNIPIHSCPKCGEV . ..: . .:..:: ...:.. ::: . : . :. .. : :::: NP_001 ASCQESARIEDMRKRH-VEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQ 350 360 370 380 390 400 560 570 pF1KB9 LPDIDTLQIHVMDCII ::.::::::::.:: NP_001 APDMDTLQIHVMECIE 410 571 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:17:33 2016 done: Thu Nov 3 23:17:34 2016 Total Scan time: 9.810 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]