FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9423, 217 aa 1>>>pF1KB9423 217 - 217 aa - 217 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2318+/-0.000743; mu= 13.6567+/- 0.044 mean_var=57.6396+/-11.655, 0's: 0 Z-trim(107.5): 13 B-trim: 0 in 0/50 Lambda= 0.168933 statistics sampled from 9585 (9594) to 9585 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.295), width: 16 Scan time: 1.780 The best scores are: opt bits E(32554) CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 ( 217) 1507 375.2 1.7e-104 CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 ( 216) 1249 312.3 1.5e-85 CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 ( 216) 1181 295.8 1.4e-80 CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 ( 268) 1181 295.8 1.7e-80 CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 ( 216) 857 216.8 8.3e-57 CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 ( 221) 857 216.8 8.5e-57 CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 ( 216) 841 212.9 1.2e-55 CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 ( 268) 440 115.2 4e-26 >>CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 (217 aa) initn: 1507 init1: 1507 opt: 1507 Z-score: 1989.4 bits: 375.2 E(32554): 1.7e-104 Smith-Waterman score: 1507; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217) 10 20 30 40 50 60 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE 130 140 150 160 170 180 190 200 210 pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH ::::::::::::::::::::::::::::::::::::: CCDS12 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 190 200 210 >>CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 (216 aa) initn: 1249 init1: 1249 opt: 1249 Z-score: 1649.6 bits: 312.3 E(32554): 1.5e-85 Smith-Waterman score: 1249; 82.1% identity (92.9% similar) in 212 aa overlap (6-217:5-216) 10 20 30 40 50 60 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW ::::::::::::::::::::::::::::.::::::.:.::. ::::: ::: ::: CCDS65 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDW 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD :::::::::::.::::::: . :::..::::::::::::::::. :..::::: ::.::. CCDS65 VAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE :::::::.:::::..::: ::.:::::::: .::: ::::::::::::::::. ::.: CCDS65 LLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAE 120 130 140 150 160 170 190 200 210 pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH :::::::::::::: :..::: ::::::::::.:::: CCDS65 AHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 180 190 200 210 >>CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 (216 aa) initn: 1181 init1: 1181 opt: 1181 Z-score: 1560.1 bits: 295.8 E(32554): 1.4e-80 Smith-Waterman score: 1181; 74.1% identity (92.9% similar) in 212 aa overlap (6-217:5-216) 10 20 30 40 50 60 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW ::::: :::::::...::::::::::.:::::::..::::: .:.:::::...:: CCDS54 MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDW 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD .::::::::::.::::::... :.: :::::.:::.::::::::...:.:. ::::::: CCDS54 IAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMA 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE :::::::. ::.:..::: ::.:::::: :. :::.::::::::::::::: : .::.: CCDS54 LLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAE 120 130 140 150 160 170 190 200 210 pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH :::::::::::::..::.:.: .:::::.::: :.:: CCDS54 AHVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 180 190 200 210 >>CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 (268 aa) initn: 1181 init1: 1181 opt: 1181 Z-score: 1558.6 bits: 295.8 E(32554): 1.7e-80 Smith-Waterman score: 1181; 74.1% identity (92.9% similar) in 212 aa overlap (6-217:57-268) 10 20 30 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKA ::::: :::::::...::::::::::.::: CCDS53 GMDEMTFHIWYPQVRAPGQQPQAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKA 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 QASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGP ::::..::::: .:.:::::...::.::::::::::.::::::... :.: :::::.::: CCDS53 QASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVMAGGP 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 KYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKI .::::::::...:.:. ::::::: :::::::. ::.:..::: ::.:::::: :. :: CCDS53 RYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKI 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 LSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARM :.::::::::::::::: : .::.::::::::::::::..::.:.: .:::::.::: :. CCDS53 LTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREMTERI 210 220 230 240 250 260 pF1KB9 CH :: CCDS53 CH >>CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 (216 aa) initn: 874 init1: 770 opt: 857 Z-score: 1133.3 bits: 216.8 E(32554): 8.3e-57 Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:11-211) 10 20 30 40 50 60 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW :::.::... :....:: :.:.:.:..: .::.::.:: :::::.: CCDS34 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEW 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD :::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.:.: CCDS34 VAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYID 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. : CCDS34 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEE 120 130 140 150 160 170 190 200 210 pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH ::.:: .::: .::.::.::: .:: ::.:. .. CCDS34 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR 180 190 200 210 >>CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 (221 aa) initn: 874 init1: 770 opt: 857 Z-score: 1133.1 bits: 216.8 E(32554): 8.5e-57 Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:16-216) 10 20 30 40 50 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLN :::.::... :....:: :.:.:.:..: .::.::.:: ::::: CCDS58 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 DWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRY .::::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.: CCDS58 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 MDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMG .: :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. CCDS58 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ 120 130 140 150 160 170 180 190 200 210 pF1KB9 SEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH :::.:: .::: .::.::.::: .:: ::.:. .. CCDS58 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR 180 190 200 210 220 >>CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 (216 aa) initn: 858 init1: 754 opt: 841 Z-score: 1112.2 bits: 212.9 E(32554): 1.2e-55 Smith-Waterman score: 841; 53.5% identity (85.1% similar) in 202 aa overlap (14-215:11-211) 10 20 30 40 50 60 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW :::.::... :....:: :.:.:.:..: .:: ::.:: :::::.: CCDS46 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEW 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD .::..:::::..:..::::.. ::: ::::::.::.:::.: : ...:: :::.:.: CCDS46 IAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYID 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. : CCDS46 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEE 120 130 140 150 160 170 190 200 210 pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH ::.:: .::: .::.::.::: .:: ::.:. .. CCDS46 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR 180 190 200 210 >>CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 (268 aa) initn: 276 init1: 276 opt: 440 Z-score: 582.6 bits: 115.2 E(32554): 4e-26 Smith-Waterman score: 440; 33.8% identity (68.1% similar) in 213 aa overlap (6-216:32-239) 10 20 30 pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKA ...:. :.:. .:. : .:.... . . . CCDS53 LGDHCSLPEDQARPGQSLQSGLCCKMVLQAVSKVLRKSKA-KPNGK-KPAAEERKAYLEP 10 20 30 40 50 40 50 60 70 80 90 pF1KB9 QASLNAGLDLRLA--VQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSG . . :... : :: :::.:.: ... ::...:: :.:::. :: ..: .:. CCDS53 EHTKARITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAV 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 GPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVR . .: : ::. : . .::.:.:..:. .. ...::.:::. : ::..: . :: CCDS53 C-NTQYYWYDERG--KKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVR 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 KILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTA :: .::.:..:.: :: . . ..:.:: : :: :..::.:.: :: . ..: CCDS53 KICRHLFHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTE 180 190 200 210 220 230 pF1KB9 RMCH .: CCDS53 VLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER 240 250 260 217 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:18:06 2016 done: Thu Nov 3 23:18:06 2016 Total Scan time: 1.780 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]