FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9434, 216 aa 1>>>pF1KB9434 216 - 216 aa - 216 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.2091+/-0.000782; mu= 13.6939+/- 0.047 mean_var=56.9596+/-11.247, 0's: 0 Z-trim(106.6): 12 B-trim: 46 in 1/50 Lambda= 0.169938 statistics sampled from 9087 (9099) to 9087 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.28), width: 16 Scan time: 1.780 The best scores are: opt bits E(32554) CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 ( 216) 1511 378.4 1.9e-105 CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 ( 217) 1249 314.2 4e-86 CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 ( 216) 1169 294.6 3.2e-80 CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 ( 268) 1169 294.6 3.9e-80 CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 ( 216) 838 213.4 8.7e-56 CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 ( 221) 838 213.4 8.9e-56 CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 ( 216) 835 212.7 1.4e-55 CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 ( 268) 429 113.2 1.6e-25 >>CCDS6520.1 MOB3B gene_id:79817|Hs108|chr9 (216 aa) initn: 1511 init1: 1511 opt: 1511 Z-score: 2006.8 bits: 378.4 E(32554): 1.9e-105 Smith-Waterman score: 1511; 100.0% identity (100.0% similar) in 216 aa overlap (1-216:1-216) 10 20 30 40 50 60 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA 130 140 150 160 170 180 190 200 210 pF1KB9 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH :::::::::::::::::::::::::::::::::::: CCDS65 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 190 200 210 >>CCDS12081.1 MOB3A gene_id:126308|Hs108|chr19 (217 aa) initn: 1249 init1: 1249 opt: 1249 Z-score: 1659.6 bits: 314.2 E(32554): 4e-86 Smith-Waterman score: 1249; 82.1% identity (92.9% similar) in 212 aa overlap (5-216:6-217) 10 20 30 40 50 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDW ::::::::::::::::::::::::::::.::::::.:.::. ::::: ::: ::: CCDS12 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 VAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMN :::::::::::.::::::: . :::..::::::::::::::::. :..::::: ::.::. CCDS12 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 LLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAE :::::::.:::::..::: ::.:::::::: .::: ::::::::::::::::. ::.: CCDS12 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE 130 140 150 160 170 180 180 190 200 210 pF1KB9 AHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH :::::::::::::: :..::: ::::::::::.:::: CCDS12 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 190 200 210 >>CCDS540.1 MOB3C gene_id:148932|Hs108|chr1 (216 aa) initn: 1169 init1: 1169 opt: 1169 Z-score: 1553.6 bits: 294.6 E(32554): 3.2e-80 Smith-Waterman score: 1169; 71.8% identity (90.3% similar) in 216 aa overlap (1-216:1-216) 10 20 30 40 50 60 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV :.. ::::: :::::::...::::::::::.:.:::::.::.::...:.:: ::. .::. CCDS54 MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL :::::::::::::::::. : :.: .::::.:::.:::::::. .:..:. : ::.:: : CCDS54 AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA :::::: ::.::.::: ::::::::: :.: ::: ::::::::::::::: .. ::::: CCDS54 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 130 140 150 160 170 180 190 200 210 pF1KB9 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH ::::::::::::. :..:.:..:::::.::: :.:: CCDS54 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 190 200 210 >>CCDS539.1 MOB3C gene_id:148932|Hs108|chr1 (268 aa) initn: 1169 init1: 1169 opt: 1169 Z-score: 1552.1 bits: 294.6 E(32554): 3.9e-80 Smith-Waterman score: 1169; 71.8% identity (90.3% similar) in 216 aa overlap (1-216:53-268) 10 20 30 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFEL :.. ::::: :::::::...:::::::::: CCDS53 SRRVGMDEMTFHIWYPQVRAPGQQPQAQLAMALCLKQVFAKDKTFRPRKRFEPGTQRFEL 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB9 HKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVM .:.:::::.::.::...:.:: ::. .::.:::::::::::::::::. : :.: .:::: CCDS53 YKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHVVDFFNRINLIYGTMAERCSETSCPVM 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB9 SGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQI .:::.:::::::. .:..:. : ::.:: ::::::: ::.::.::: ::::::::: :. CCDS53 AGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDWIEGLINDEEVFPTRVGVPFPKNFQQV 150 160 170 180 190 200 160 170 180 190 200 210 pF1KB9 CKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEM : ::: ::::::::::::::: .. :::::::::::::::::. :..:.:..:::::.:: CCDS53 CTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNTCYKHFYYFIREFSLVDQRELEPLREM 210 220 230 240 250 260 pF1KB9 TSRMCH : :.:: CCDS53 TERICH >>CCDS34002.1 MOB1B gene_id:92597|Hs108|chr4 (216 aa) initn: 848 init1: 740 opt: 838 Z-score: 1115.0 bits: 213.4 E(32554): 8.7e-56 Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (13-214:11-211) 10 20 30 40 50 60 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV :::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.:: CCDS34 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWV 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL ::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.:.. CCDS34 AVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDY 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA :: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :: . :: CCDS34 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEA 120 130 140 150 160 170 190 200 210 pF1KB9 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH :.:: .::: .:: :.:::::.:: ::.:. .. CCDS34 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR 180 190 200 210 >>CCDS58903.1 MOB1B gene_id:92597|Hs108|chr4 (221 aa) initn: 848 init1: 740 opt: 838 Z-score: 1114.9 bits: 213.4 E(32554): 8.9e-56 Smith-Waterman score: 838; 55.4% identity (82.7% similar) in 202 aa overlap (13-214:16-216) 10 20 30 40 50 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQN :::.::... :....:: :.:.:.:.:: .:. ::.:: ::: : CCDS58 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN 10 20 30 40 50 60 70 80 90 100 110 pF1KB9 DWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQY .::::..:::::.::..:::: .::::..:::::.::::::.: : . ::: ::.: CCDS58 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB9 MNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMG .. :: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :: . CCDS58 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ 120 130 140 150 160 170 180 190 200 210 pF1KB9 AEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH :::.:: .::: .:: :.:::::.:: ::.:. .. CCDS58 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR 180 190 200 210 220 >>CCDS46340.1 MOB1A gene_id:55233|Hs108|chr2 (216 aa) initn: 845 init1: 737 opt: 835 Z-score: 1111.1 bits: 212.7 E(32554): 1.4e-55 Smith-Waterman score: 835; 54.5% identity (82.2% similar) in 202 aa overlap (13-214:11-211) 10 20 30 40 50 60 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV :::.::... :....:: :.:.:.:.:: .:. ::.:: ::: :.:. CCDS46 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWI 10 20 30 40 50 70 80 90 100 110 120 pF1KB9 AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL ::..:::::.::..:::: ::::: .:::::.::.:::.: : . ::: ::.:.. CCDS46 AVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDY 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB9 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA :: :.. :...: .::. .::::::::... : :: :::::..:.: .::: :. . :: CCDS46 LMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEA 120 130 140 150 160 170 190 200 210 pF1KB9 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH :.:: .::: .:: :.:::::.:: ::.:. .. CCDS46 HLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR 180 190 200 210 >>CCDS53591.1 MOB2 gene_id:81532|Hs108|chr11 (268 aa) initn: 252 init1: 252 opt: 429 Z-score: 571.6 bits: 113.2 E(32554): 1.6e-25 Smith-Waterman score: 429; 34.4% identity (67.4% similar) in 215 aa overlap (4-215:31-239) 10 20 30 pF1KB9 MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKR :...:. :.:. .:. : .:.... . . . CCDS53 MLGDHCSLPEDQARPGQSLQSGLCCKMVLQAVSKVLRKSKA-KPNGK-KPAAEERKAYLE 10 20 30 40 50 40 50 60 70 80 90 pF1KB9 AQASLNSGVDL--KAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMS . . .:. : : :: : :.:.: ... ::..::: :.:: :::: .:: .:. CCDS53 PEHTKARITDFQFKELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMA 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB9 GGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQIC . .: : :. : . ::::....:. .. ...:..::: : ::..: .. CCDS53 VC-NTQYYWYDE--RGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLV 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB9 KKILCR-LFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEM .:: :: ::.:..:.: :: ..... ..:.:: : :: :. :.::.: :: . .. CCDS53 RKI-CRHLFHVLAHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDL 180 190 200 210 220 230 pF1KB9 TSRMCH : .: CCDS53 TEVLCSGAGGVHSGGSGDGAGSGGPGAQNHVKER 240 250 260 216 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:02:31 2016 done: Fri Nov 4 17:02:31 2016 Total Scan time: 1.780 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]