Result of FASTA (omim) for pF1KB9435
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB9435, 216 aa
  1>>>pF1KB9435 216 - 216 aa - 216 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9106+/-0.000348; mu= 15.4967+/- 0.022
 mean_var=55.7462+/-11.409, 0's: 0 Z-trim(112.5): 28  B-trim: 1109 in 1/52
 Lambda= 0.171778
 statistics sampled from 21390 (21418) to 21390 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.644), E-opt: 0.2 (0.251), width:  16
 Scan time:  4.990

The best scores are:                                      opt bits E(85289)
NP_060691 (OMIM: 609281) MOB kinase activator 1A i ( 216) 1439 364.6 7.1e-101
NP_001304039 (OMIM: 609281) MOB kinase activator 1 ( 215) 1428 361.8 4.7e-100
NP_001304040 (OMIM: 609281) MOB kinase activator 1 ( 258) 1427 361.6 6.5e-100
NP_775739 (OMIM: 609282) MOB kinase activator 1B i ( 216) 1391 352.7 2.7e-97
XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase  ( 247) 1388 352.0 5.1e-97
NP_001231695 (OMIM: 609282) MOB kinase activator 1 ( 221) 1379 349.7 2.2e-96
XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase  ( 221) 1379 349.7 2.2e-96
XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase  ( 240) 1379 349.7 2.3e-96
NP_001304041 (OMIM: 609281) MOB kinase activator 1 ( 138)  922 236.3 1.8e-62
XP_011531250 (OMIM: 609281) PREDICTED: MOB kinase  ( 180)  910 233.4 1.8e-61
NP_001231696 (OMIM: 609282) MOB kinase activator 1 ( 147)  894 229.4 2.3e-60
NP_001165694 (OMIM: 611969) MOB kinase activator 2 ( 268)  551 144.6 1.5e-34
NP_443731 (OMIM: 611969) MOB kinase activator 2 is ( 237)  548 143.8 2.3e-34
NP_001191023 (OMIM: 609361) MOB-like protein phoce ( 193)  190 55.0 9.8e-08
NP_955776 (OMIM: 609361) MOB-like protein phocein  ( 193)  190 55.0 9.8e-08
NP_001094289 (OMIM: 609361) MOB-like protein phoce ( 204)  190 55.0   1e-07
NP_056202 (OMIM: 609361) MOB-like protein phocein  ( 225)  190 55.0 1.1e-07


>>NP_060691 (OMIM: 609281) MOB kinase activator 1A isofo  (216 aa)
 initn: 1439 init1: 1439 opt: 1439  Z-score: 1932.0  bits: 364.6 E(85289): 7.1e-101
Smith-Waterman score: 1439; 98.6% identity (99.1% similar) in 216 aa overlap (1-216:1-216)

               10        20        30        40        50        60
pF1KB9 MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
       : : .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
              130       140       150       160       170       180

              190       200       210      
pF1KB9 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
       ::::::::::::::::::::::::::::::::::::
NP_060 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
              190       200       210      

>>NP_001304039 (OMIM: 609281) MOB kinase activator 1A is  (215 aa)
 initn: 1428 init1: 1428 opt: 1428  Z-score: 1917.3  bits: 361.8 E(85289): 4.7e-100
Smith-Waterman score: 1428; 99.1% identity (99.5% similar) in 213 aa overlap (4-216:3-215)

               10        20        30        40        50        60
pF1KB9 MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
          .: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001  MSFLFSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
                10        20        30        40        50         

               70        80        90       100       110       120
pF1KB9 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
      60        70        80        90       100       110         

              130       140       150       160       170       180
pF1KB9 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
     120       130       140       150       160       170         

              190       200       210      
pF1KB9 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
       ::::::::::::::::::::::::::::::::::::
NP_001 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
     180       190       200       210     

>>NP_001304040 (OMIM: 609281) MOB kinase activator 1A is  (258 aa)
 initn: 1427 init1: 1427 opt: 1427  Z-score: 1914.7  bits: 361.6 E(85289): 6.5e-100
Smith-Waterman score: 1427; 100.0% identity (100.0% similar) in 211 aa overlap (6-216:48-258)

                                        10        20        30     
pF1KB9                          MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEAT
                                     ::::::::::::::::::::::::::::::
NP_001 RCWPWSRIVLSSSDSAHLLALILTNFSCPRSSRSSKTFKPKKNIPEGSHQYELLKHAEAT
        20        30        40        50        60        70       

          40        50        60        70        80        90     
pF1KB9 LGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEY
        80        90       100       110       120       130       

         100       110       120       130       140       150     
pF1KB9 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
       140       150       160       170       180       190       

         160       170       180       190       200       210     
pF1KB9 FRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKD
       200       210       220       230       240       250       

        
pF1KB9 R
       :
NP_001 R
        

>>NP_775739 (OMIM: 609282) MOB kinase activator 1B isofo  (216 aa)
 initn: 1391 init1: 1391 opt: 1391  Z-score: 1867.7  bits: 352.7 E(85289): 2.7e-97
Smith-Waterman score: 1391; 94.4% identity (97.7% similar) in 216 aa overlap (1-216:1-216)

               10        20        30        40        50        60
pF1KB9 MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
       : : ..::::::::::::::::::::::::::::::::::::.:::::::::::::.:::
NP_775 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::.:::: :::::::::.::::::::::::::::::::::::::::
NP_775 TVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
       :::::::::::::::::::::::::::::::::::::::::::::::: :.:::::::::
NP_775 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLN
              130       140       150       160       170       180

              190       200       210      
pF1KB9 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
       ::::::::::::::::::::::::::::::: ::::
NP_775 TSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210      

>>XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase acti  (247 aa)
 initn: 1388 init1: 1388 opt: 1388  Z-score: 1862.8  bits: 352.0 E(85289): 5.1e-97
Smith-Waterman score: 1388; 94.9% identity (98.1% similar) in 214 aa overlap (3-216:34-247)

                                           10        20        30  
pF1KB9                             MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHA
                                     .: .::::::::::::::::::::::::::
XP_016 SGMTTANCSFDFPGSGDPFISNPLPATSSWYYSGSRSSKTFKPKKNIPEGSHQYELLKHA
            10        20        30        40        50        60   

             40        50        60        70        80        90  
pF1KB9 EATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPR
       ::::::::::.:::::::::::::.:::::::::::::::::::.:::: :::::::::.
XP_016 EATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPK
            70        80        90       100       110       120   

            100       110       120       130       140       150  
pF1KB9 YEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTIL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTIL
           130       140       150       160       170       180   

            160       170       180       190       200       210  
pF1KB9 KRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG
       :::::::::::::::: :.:::::::::::::::::::::::::::::::::::::::: 
XP_016 KRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLT
           190       200       210       220       230       240   

           
pF1KB9 SKDR
       ::::
XP_016 SKDR
           

>>NP_001231695 (OMIM: 609282) MOB kinase activator 1B is  (221 aa)
 initn: 1379 init1: 1379 opt: 1379  Z-score: 1851.5  bits: 349.7 E(85289): 2.2e-96
Smith-Waterman score: 1379; 96.2% identity (98.6% similar) in 210 aa overlap (7-216:12-221)

                    10        20        30        40        50     
pF1KB9      MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNE
                  ::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB9 WIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYI
       :.:::::::::::::::::::.:::: :::::::::.:::::::::::::::::::::::
NP_001 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KB9 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: :.::::
NP_001 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
              130       140       150       160       170       180

         180       190       200       210      
pF1KB9 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
       :::::::::::::::::::::::::::::::::::: ::::
NP_001 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210       220 

>>XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase acti  (221 aa)
 initn: 1379 init1: 1379 opt: 1379  Z-score: 1851.5  bits: 349.7 E(85289): 2.2e-96
Smith-Waterman score: 1379; 96.2% identity (98.6% similar) in 210 aa overlap (7-216:12-221)

                    10        20        30        40        50     
pF1KB9      MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNE
                  ::::::::::::::::::::::::::::::::::::.::::::::::::
XP_005 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNE
               10        20        30        40        50        60

          60        70        80        90       100       110     
pF1KB9 WIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYI
       :.:::::::::::::::::::.:::: :::::::::.:::::::::::::::::::::::
XP_005 WVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYI
               70        80        90       100       110       120

         120       130       140       150       160       170     
pF1KB9 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::: :.::::
XP_005 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQE
              130       140       150       160       170       180

         180       190       200       210      
pF1KB9 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
       :::::::::::::::::::::::::::::::::::: ::::
XP_005 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210       220 

>>XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase acti  (240 aa)
 initn: 1379 init1: 1379 opt: 1379  Z-score: 1850.9  bits: 349.7 E(85289): 2.3e-96
Smith-Waterman score: 1379; 96.2% identity (98.6% similar) in 210 aa overlap (7-216:31-240)

                                       10        20        30      
pF1KB9                         MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEATL
                                     ::::::::::::::::::::::::::::::
XP_011 MTPNRVDRGAGQPRRTRWASSLAAEETRSGSRSSKTFKPKKNIPEGSHQYELLKHAEATL
               10        20        30        40        50        60

         40        50        60        70        80        90      
pF1KB9 GSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYH
       ::::::.:::::::::::::.:::::::::::::::::::.:::: :::::::::.::::
XP_011 GSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYH
               70        80        90       100       110       120

        100       110       120       130       140       150      
pF1KB9 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLF
              130       140       150       160       170       180

        160       170       180       190       200       210      
pF1KB9 RVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
       :::::::::::: :.:::::::::::::::::::::::::::::::::::::::: ::::
XP_011 RVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
              190       200       210       220       230       240

>>NP_001304041 (OMIM: 609281) MOB kinase activator 1A is  (138 aa)
 initn: 922 init1: 922 opt: 922  Z-score: 1242.5  bits: 236.3 E(85289): 1.8e-62
Smith-Waterman score: 922; 97.8% identity (98.6% similar) in 138 aa overlap (1-138:1-138)

               10        20        30        40        50        60
pF1KB9 MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
       : : .:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVN
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB9 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB9 WVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLN
       ::::::::::::::::::                                          
NP_001 WVQDQLDDETLFPSKIGV                                          
              130                                                  

>>XP_011531250 (OMIM: 609281) PREDICTED: MOB kinase acti  (180 aa)
 initn: 910 init1: 910 opt: 910  Z-score: 1224.7  bits: 233.4 E(85289): 1.8e-61
Smith-Waterman score: 910; 100.0% identity (100.0% similar) in 133 aa overlap (6-138:48-180)

                                        10        20        30     
pF1KB9                          MLFYLSSRSSKTFKPKKNIPEGSHQYELLKHAEAT
                                     ::::::::::::::::::::::::::::::
XP_011 RCWPWSRIVLSSSDSAHLLALILTNFSCPRSSRSSKTFKPKKNIPEGSHQYELLKHAEAT
        20        30        40        50        60        70       

          40        50        60        70        80        90     
pF1KB9 LGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEY
        80        90       100       110       120       130       

         100       110       120       130       140       150     
pF1KB9 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRL
       :::::::::::::::::::::::::::::::::::::::::::                 
XP_011 HWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGV                 
       140       150       160       170       180                 

         160       170       180       190       200       210     
pF1KB9 FRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKD




216 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 02:14:33 2016 done: Sat Nov  5 02:14:34 2016
 Total Scan time:  4.990 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]
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