FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9443, 307 aa 1>>>pF1KB9443 307 - 307 aa - 307 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8622+/-0.000745; mu= 5.7036+/- 0.046 mean_var=137.3165+/-27.348, 0's: 0 Z-trim(114.7): 5 B-trim: 3 in 1/54 Lambda= 0.109449 statistics sampled from 15219 (15223) to 15219 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.784), E-opt: 0.2 (0.468), width: 16 Scan time: 2.800 The best scores are: opt bits E(32554) CCDS11273.1 CDK5R1 gene_id:8851|Hs108|chr17 ( 307) 2038 332.2 3e-91 CCDS2427.1 CDK5R2 gene_id:8941|Hs108|chr2 ( 367) 820 140.0 2.7e-33 >>CCDS11273.1 CDK5R1 gene_id:8851|Hs108|chr17 (307 aa) initn: 2038 init1: 2038 opt: 2038 Z-score: 1751.8 bits: 332.2 E(32554): 3e-91 Smith-Waterman score: 2038; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307) 10 20 30 40 50 60 pF1KB9 MGTVLSLSPSYRKATLFEDGAATVGHYTAVQNSKNAKDKNLKRHSIISVLPWKRIVAVSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 MGTVLSLSPSYRKATLFEDGAATVGHYTAVQNSKNAKDKNLKRHSIISVLPWKRIVAVSA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KKKNSKKVQPNSSYQNNITHLNNENLKKSLSCANLSTFAQPPPAQPPAPPASQLSGSQTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 KKKNSKKVQPNSSYQNNITHLNNENLKKSLSCANLSTFAQPPPAQPPAPPASQLSGSQTG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 GSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 VDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 VDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 ISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS11 ISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKR 250 260 270 280 290 300 pF1KB9 LLLGLDR ::::::: CCDS11 LLLGLDR >>CCDS2427.1 CDK5R2 gene_id:8941|Hs108|chr2 (367 aa) initn: 917 init1: 419 opt: 820 Z-score: 711.2 bits: 140.0 E(32554): 2.7e-33 Smith-Waterman score: 936; 52.0% identity (72.6% similar) in 325 aa overlap (4-292:4-328) 10 20 30 40 pF1KB9 MGTVLSLSPS-----YRKATLFED-------GAATVGHYTAVQNSKNAKDKN-LKRHSI- ::::::. : . : :. : ..: : : .:..: .. ::: :. CCDS24 MGTVLSLSPASSAKGRRPGGLPEEKKKAPPAGDEALGGYGAPPVGKGGKGESRLKRPSVL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB9 ISVLPWKRIVAVSAKKKN-SKKVQPNSSYQNN---ITHLNNENL-KKSLSCANLSTFAQP ::.: :::.::.:::::. :::: :. . . . . : ::: .:. . . . :.: CCDS24 ISALTWKRLVAASAKKKKGSKKVTPKPASTGPDPLVQQRNRENLLRKGRDPPDGGGTAKP 70 80 90 100 110 120 110 120 130 140 pF1KB9 ---P-PAQPPA-----PPASQLSGSQTGGSSSVKKAPHPAVTS-------AGTPKRVIVQ : :. : : ::.. ...: ::.. : : : . .:.:.::::: CCDS24 LAVPVPTVPAAAATCEPPSGGSAAAQPPGSGGGKPPPPPPPAPQVAPPVPGGSPRRVIVQ 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 ASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLY :::.:::::::.:.::::::::.::: . : :.:.:::::::::::::.::::::.::.: CCDS24 ASTGELLRCLGDFVCRRCYRLKELSPGELVGWFRGVDRSLLLQGWQDQAFITPANLVFVY 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB9 MLCRDVI-SSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSV .:::. . ..:..: ::::..::::::.:::::::::::::::::: :: ::.::: . CCDS24 LLCRESLRGDELASAAELQAAFLTCLYLAYSYMGNEISYPLKPFLVEPDKERFWQRCLRL 250 260 270 280 290 300 270 280 290 300 pF1KB9 INLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR :. .: .::..:::::.:::::.::::: CCDS24 IQRLSPQMLRLNADPHFFTQVFQDLKNEGEAAASGGGPPSGGAPAASSAARDSCAAGTKH 310 320 330 340 350 360 307 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:24:16 2016 done: Thu Nov 3 23:24:16 2016 Total Scan time: 2.800 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]