FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9445, 672 aa 1>>>pF1KB9445 672 - 672 aa - 672 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.5410+/-0.00056; mu= -2.8164+/- 0.035 mean_var=752.7833+/-204.143, 0's: 0 Z-trim(117.1): 164 B-trim: 1750 in 1/56 Lambda= 0.046745 statistics sampled from 28648 (28815) to 28648 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.338), width: 16 Scan time: 10.750 The best scores are: opt bits E(85289) NP_006768 (OMIM: 300329) transcriptional regulator ( 672) 4391 312.9 2.5e-84 NP_001171671 (OMIM: 300329) transcriptional regula ( 672) 4391 312.9 2.5e-84 XP_006721627 (OMIM: 612308) PREDICTED: zinc finger (1013) 443 46.9 0.00044 XP_011522274 (OMIM: 612308) PREDICTED: zinc finger (1013) 443 46.9 0.00044 NP_065950 (OMIM: 612308) zinc finger and BTB domai (1013) 443 46.9 0.00044 XP_006721626 (OMIM: 612308) PREDICTED: zinc finger (1013) 443 46.9 0.00044 NP_001122305 (OMIM: 612308) zinc finger and BTB do (1013) 443 46.9 0.00044 XP_016861545 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861547 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_005247318 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861544 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861549 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861550 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861541 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861548 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_011510913 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861543 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_005247314 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_005247315 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_016861546 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 NP_001073881 (OMIM: 612218) zinc finger and BTB do (1195) 442 47.0 0.0005 XP_016861542 (OMIM: 612218) PREDICTED: zinc finger (1195) 442 47.0 0.0005 XP_005247313 (OMIM: 612218) PREDICTED: zinc finger (1196) 442 47.0 0.0005 XP_016861540 (OMIM: 612218) PREDICTED: zinc finger (1221) 442 47.0 0.0005 XP_011510909 (OMIM: 612218) PREDICTED: zinc finger (1221) 442 47.0 0.0005 XP_016861539 (OMIM: 612218) PREDICTED: zinc finger (1221) 442 47.0 0.0005 XP_011510910 (OMIM: 612218) PREDICTED: zinc finger (1221) 442 47.0 0.0005 XP_016884158 (OMIM: 607712) PREDICTED: hypermethyl ( 597) 392 43.1 0.0036 XP_011528311 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 392 43.1 0.0037 XP_011528310 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 392 43.1 0.0037 XP_011528312 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 392 43.1 0.0037 XP_011528309 (OMIM: 607712) PREDICTED: hypermethyl ( 615) 392 43.1 0.0037 NP_055909 (OMIM: 607712) hypermethylated in cancer ( 615) 392 43.1 0.0037 >>NP_006768 (OMIM: 300329) transcriptional regulator Kai (672 aa) initn: 4391 init1: 4391 opt: 4391 Z-score: 1634.9 bits: 312.9 E(85289): 2.5e-84 Smith-Waterman score: 4391; 100.0% identity (100.0% similar) in 672 aa overlap (1-672:1-672) 10 20 30 40 50 60 pF1KB9 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 FSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 HMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 HMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 TSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 ATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 EIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 SDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDG 610 620 630 640 650 660 670 pF1KB9 STEFEFIIPESY :::::::::::: NP_006 STEFEFIIPESY 670 >>NP_001171671 (OMIM: 300329) transcriptional regulator (672 aa) initn: 4391 init1: 4391 opt: 4391 Z-score: 1634.9 bits: 312.9 E(85289): 2.5e-84 Smith-Waterman score: 4391; 100.0% identity (100.0% similar) in 672 aa overlap (1-672:1-672) 10 20 30 40 50 60 pF1KB9 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 FSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FSVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIAELGVPL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 SQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SQVKSISGTAQDGNTEPLPPDSGDKNLVIQKSKDEAQDNGATIMPIITESFSLSAEDYEM 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 KKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KKIIVTDSDDDDDDVIFCSEILPTKETLPSNNTVAQVQSNPGPVAISDVAPSASNNSPPL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 TNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNITPTQKLPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPLSTPPNVSSSLPN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 HMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HMPSSINLLVQNQQTPNSAILTGNKANEEEEEEIIDDDDDTISSSPDSAVSNTSLVPQAD 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 TSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSQNTSFDGSLIQKMQIPTLLQEPLSNSLKISDIITRNTNDPGVGSKHLMEGQKIITLDT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ATEIEGLSTGCKVYANIGEDTYDIVIPVKDDPDEGEARLENEIPKTSGSEMANKRMKVKH 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKYPCRYCEKVFPLAEYRTKH 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 EIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQDPSGDSKLYRLHPCRSLQIRQYAYL 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 SDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDRSSTIPAMKDDGIGYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDG 610 620 630 640 650 660 670 pF1KB9 STEFEFIIPESY :::::::::::: NP_001 STEFEFIIPESY 670 >>XP_006721627 (OMIM: 612308) PREDICTED: zinc finger and (1013 aa) initn: 625 init1: 353 opt: 443 Z-score: 194.4 bits: 46.9 E(85289): 0.00044 Smith-Waterman score: 465; 41.9% identity (60.5% similar) in 172 aa overlap (482-637:297-467) 460 470 480 490 500 510 pF1KB9 PDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRR .: .: :.: :.: .:.:::: :.::.: XP_006 GLGAGGAGPGGPAGVDASALPPPVGFRGGPEHVVKVVGGHVLYVCAACERSYVTLSSLKR 270 280 290 300 310 320 520 530 540 550 560 570 pF1KB9 HFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKS : :.:::..::::::::::: :::::::::. :::::::::. : ..:..: ...: .. XP_006 HSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRA 330 340 350 360 370 380 580 590 600 610 pF1KB9 VHS---------QDPSGDSK-------LYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGI :. . :.: : :::: : :. . : : :. . : . XP_006 FHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRAAK-RPYKTYSQGAPEAPLSPTLNT 390 400 410 420 430 440 620 630 640 650 660 670 pF1KB9 GYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY : :: : . . : XP_006 PAPVAMPASPPPGPPPAPEPGPPPSVITFAHPAPSVIVHGGSSSGGGGSGTASTGGSQAA 450 460 470 480 490 500 >>XP_011522274 (OMIM: 612308) PREDICTED: zinc finger and (1013 aa) initn: 625 init1: 353 opt: 443 Z-score: 194.4 bits: 46.9 E(85289): 0.00044 Smith-Waterman score: 465; 41.9% identity (60.5% similar) in 172 aa overlap (482-637:297-467) 460 470 480 490 500 510 pF1KB9 PDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRR .: .: :.: :.: .:.:::: :.::.: XP_011 GLGAGGAGPGGPAGVDASALPPPVGFRGGPEHVVKVVGGHVLYVCAACERSYVTLSSLKR 270 280 290 300 310 320 520 530 540 550 560 570 pF1KB9 HFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKS : :.:::..::::::::::: :::::::::. :::::::::. : ..:..: ...: .. XP_011 HSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRA 330 340 350 360 370 380 580 590 600 610 pF1KB9 VHS---------QDPSGDSK-------LYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGI :. . :.: : :::: : :. . : : :. . : . XP_011 FHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRAAK-RPYKTYSQGAPEAPLSPTLNT 390 400 410 420 430 440 620 630 640 650 660 670 pF1KB9 GYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY : :: : . . : XP_011 PAPVAMPASPPPGPPPAPEPGPPPSVITFAHPAPSVIVHGGSSSGGGGSGTASTGGSQAA 450 460 470 480 490 500 >>NP_065950 (OMIM: 612308) zinc finger and BTB domain-co (1013 aa) initn: 625 init1: 353 opt: 443 Z-score: 194.4 bits: 46.9 E(85289): 0.00044 Smith-Waterman score: 465; 41.9% identity (60.5% similar) in 172 aa overlap (482-637:297-467) 460 470 480 490 500 510 pF1KB9 PDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRR .: .: :.: :.: .:.:::: :.::.: NP_065 GLGAGGAGPGGPAGVDASALPPPVGFRGGPEHVVKVVGGHVLYVCAACERSYVTLSSLKR 270 280 290 300 310 320 520 530 540 550 560 570 pF1KB9 HFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKS : :.:::..::::::::::: :::::::::. :::::::::. : ..:..: ...: .. NP_065 HSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRA 330 340 350 360 370 380 580 590 600 610 pF1KB9 VHS---------QDPSGDSK-------LYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGI :. . :.: : :::: : :. . : : :. . : . NP_065 FHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRAAK-RPYKTYSQGAPEAPLSPTLNT 390 400 410 420 430 440 620 630 640 650 660 670 pF1KB9 GYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY : :: : . . : NP_065 PAPVAMPASPPPGPPPAPEPGPPPSVITFAHPAPSVIVHGGSSSGGGGSGTASTGGSQAA 450 460 470 480 490 500 >>XP_006721626 (OMIM: 612308) PREDICTED: zinc finger and (1013 aa) initn: 625 init1: 353 opt: 443 Z-score: 194.4 bits: 46.9 E(85289): 0.00044 Smith-Waterman score: 465; 41.9% identity (60.5% similar) in 172 aa overlap (482-637:297-467) 460 470 480 490 500 510 pF1KB9 PDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRR .: .: :.: :.: .:.:::: :.::.: XP_006 GLGAGGAGPGGPAGVDASALPPPVGFRGGPEHVVKVVGGHVLYVCAACERSYVTLSSLKR 270 280 290 300 310 320 520 530 540 550 560 570 pF1KB9 HFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKS : :.:::..::::::::::: :::::::::. :::::::::. : ..:..: ...: .. XP_006 HSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRA 330 340 350 360 370 380 580 590 600 610 pF1KB9 VHS---------QDPSGDSK-------LYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGI :. . :.: : :::: : :. . : : :. . : . XP_006 FHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRAAK-RPYKTYSQGAPEAPLSPTLNT 390 400 410 420 430 440 620 630 640 650 660 670 pF1KB9 GYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY : :: : . . : XP_006 PAPVAMPASPPPGPPPAPEPGPPPSVITFAHPAPSVIVHGGSSSGGGGSGTASTGGSQAA 450 460 470 480 490 500 >>NP_001122305 (OMIM: 612308) zinc finger and BTB domain (1013 aa) initn: 625 init1: 353 opt: 443 Z-score: 194.4 bits: 46.9 E(85289): 0.00044 Smith-Waterman score: 465; 41.9% identity (60.5% similar) in 172 aa overlap (482-637:297-467) 460 470 480 490 500 510 pF1KB9 PDEGEARLENEIPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRR .: .: :.: :.: .:.:::: :.::.: NP_001 GLGAGGAGPGGPAGVDASALPPPVGFRGGPEHVVKVVGGHVLYVCAACERSYVTLSSLKR 270 280 290 300 310 320 520 530 540 550 560 570 pF1KB9 HFNIHSWEKKYPCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKS : :.:::..::::::::::: :::::::::. :::::::::. : ..:..: ...: .. NP_001 HSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRA 330 340 350 360 370 380 580 590 600 610 pF1KB9 VHS---------QDPSGDSK-------LYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGI :. . :.: : :::: : :. . : : :. . : . NP_001 FHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRAAK-RPYKTYSQGAPEAPLSPTLNT 390 400 410 420 430 440 620 630 640 650 660 670 pF1KB9 GYKVDTGKEPPVGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY : :: : . . : NP_001 PAPVAMPASPPPGPPPAPEPGPPPSVITFAHPAPSVIVHGGSSSGGGGSGTASTGGSQAA 450 460 470 480 490 500 >>XP_016861545 (OMIM: 612218) PREDICTED: zinc finger and (1195 aa) initn: 756 init1: 442 opt: 442 Z-score: 193.4 bits: 47.0 E(85289): 0.0005 Smith-Waterman score: 786; 30.3% identity (58.9% similar) in 633 aa overlap (14-613:15-592) 10 20 30 40 50 pF1KB9 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQ .: ..:. ::::: .:..::::.:::: ::.::.:.:.::: ::.. XP_016 MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LF-----SVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIA .: ....:.::. ..::.:.::::::::: .: :.. . .: .:. ::..:. XP_016 IFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 ELGVPLSQVKSISGTAQDGNTEPLPPD-SGDKNLVIQKSKDEAQDNGATIM--PIITESF .: : .. .. : : .. :... :.: . . .: : ::..: XP_016 DL------------TDRNFSNSPGPYVFCITEKGVVKEEKNEKRHEEPAITNGPRITNAF 130 140 150 160 180 190 200 210 220 pF1KB9 SLSAEDYEMKKIIVTDSDDDDDDVIFCSEILPT--KETLPSNNTVAQVQSNPGPVAISDV : :: :..... .: : . :.. : :.. .. XP_016 S----------IIETENSNN----MFSPLDLRASFKKVSDSMRTASLCLERTDVCHEAEP 170 180 190 200 210 230 240 250 260 270 280 pF1KB9 APSASNNSPPLTNITPTQK-LPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPL . . ...: ..... . . :. .... . :.:. . .: :. .: . XP_016 VRTLAEHSYAVSSVAEAYRSQPVREHDGSSPGNTGKENCEALAAK----PKTCRKPKT-F 220 230 240 250 260 290 300 310 320 330 340 pF1KB9 STPPNVSSSLPNHMPSSI-NLLVQNQQTPN-SAILTGNKA-NEEEEEEIIDDDDDTISSS : : . .:. : : . :: :.....:. .:.:: .:. :.: . .. .:.. :. XP_016 SIPQDSDSATENIPPPPVSNLEVNQERSPQPAAVLTRSKSPNNEGDVHFSREDENQSSDV 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB9 PDSAVSNTSLVPQADTSQNTSFDGS--LIQKMQIPTLLQEPLSNSLKISDIITRNTNDPG : .... . . . .::.: : .::. :::: . ... : : : XP_016 PGPPAAEVPPLVYNCSCCSKAFDSSTLLSAHMQLHKPTQEPLVCKYCNKQFTTLNRLD-- 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB9 VGSKHLMEGQKIITLDTATEIEGLSTGC-KVYANIGEDTYDIVIPVKDDPDEGEARLENE .: ..: .. : : . . : .::.. ... : .: .: :. .: XP_016 ---RH----EQICMRSSHMPIPGGNQRFLENYPTIGQNGGSFTGP---EPLLSENRI-GE 390 400 410 420 430 470 480 490 500 510 520 pF1KB9 IPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKY . ...:: . . ::. .:.:.. : :.::::::: :.::::: :.:::.. : XP_016 F-SSTGSTLPDT-------DHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTY 440 450 460 470 480 530 540 550 560 570 pF1KB9 PCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQD------ ::.::.::: ::::::.::: :::::::::. : ..:..: ....: :: :. : XP_016 PCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSIS 490 500 510 520 530 540 580 590 600 610 620 pF1KB9 ---------PS-GDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPP :: ::::: : .. .. : : :.:. ... XP_016 KKTANGGLKPSVYPYKLYRLLP---MKCKRAPYKSYRNSSYENARENSQMNESAPGTYVV 550 560 570 580 590 600 630 640 650 660 670 pF1KB9 VGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY XP_016 QNPHSSELPTLNFQDTVNTLTNSPAIPLETSACQDIPTSANVQNAEGTKWGEEALKMDLD 610 620 630 640 650 660 >>XP_016861547 (OMIM: 612218) PREDICTED: zinc finger and (1195 aa) initn: 756 init1: 442 opt: 442 Z-score: 193.4 bits: 47.0 E(85289): 0.0005 Smith-Waterman score: 786; 30.3% identity (58.9% similar) in 633 aa overlap (14-613:15-592) 10 20 30 40 50 pF1KB9 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQ .: ..:. ::::: .:..::::.:::: ::.::.:.:.::: ::.. XP_016 MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LF-----SVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIA .: ....:.::. ..::.:.::::::::: .: :.. . .: .:. ::..:. XP_016 IFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 ELGVPLSQVKSISGTAQDGNTEPLPPD-SGDKNLVIQKSKDEAQDNGATIM--PIITESF .: : .. .. : : .. :... :.: . . .: : ::..: XP_016 DL------------TDRNFSNSPGPYVFCITEKGVVKEEKNEKRHEEPAITNGPRITNAF 130 140 150 160 180 190 200 210 220 pF1KB9 SLSAEDYEMKKIIVTDSDDDDDDVIFCSEILPT--KETLPSNNTVAQVQSNPGPVAISDV : :: :..... .: : . :.. : :.. .. XP_016 S----------IIETENSNN----MFSPLDLRASFKKVSDSMRTASLCLERTDVCHEAEP 170 180 190 200 210 230 240 250 260 270 280 pF1KB9 APSASNNSPPLTNITPTQK-LPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPL . . ...: ..... . . :. .... . :.:. . .: :. .: . XP_016 VRTLAEHSYAVSSVAEAYRSQPVREHDGSSPGNTGKENCEALAAK----PKTCRKPKT-F 220 230 240 250 260 290 300 310 320 330 340 pF1KB9 STPPNVSSSLPNHMPSSI-NLLVQNQQTPN-SAILTGNKA-NEEEEEEIIDDDDDTISSS : : . .:. : : . :: :.....:. .:.:: .:. :.: . .. .:.. :. XP_016 SIPQDSDSATENIPPPPVSNLEVNQERSPQPAAVLTRSKSPNNEGDVHFSREDENQSSDV 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB9 PDSAVSNTSLVPQADTSQNTSFDGS--LIQKMQIPTLLQEPLSNSLKISDIITRNTNDPG : .... . . . .::.: : .::. :::: . ... : : : XP_016 PGPPAAEVPPLVYNCSCCSKAFDSSTLLSAHMQLHKPTQEPLVCKYCNKQFTTLNRLD-- 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB9 VGSKHLMEGQKIITLDTATEIEGLSTGC-KVYANIGEDTYDIVIPVKDDPDEGEARLENE .: ..: .. : : . . : .::.. ... : .: .: :. .: XP_016 ---RH----EQICMRSSHMPIPGGNQRFLENYPTIGQNGGSFTGP---EPLLSENRI-GE 390 400 410 420 430 470 480 490 500 510 520 pF1KB9 IPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKY . ...:: . . ::. .:.:.. : :.::::::: :.::::: :.:::.. : XP_016 F-SSTGSTLPDT-------DHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTY 440 450 460 470 480 530 540 550 560 570 pF1KB9 PCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQD------ ::.::.::: ::::::.::: :::::::::. : ..:..: ....: :: :. : XP_016 PCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSIS 490 500 510 520 530 540 580 590 600 610 620 pF1KB9 ---------PS-GDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPP :: ::::: : .. .. : : :.:. ... XP_016 KKTANGGLKPSVYPYKLYRLLP---MKCKRAPYKSYRNSSYENARENSQMNESAPGTYVV 550 560 570 580 590 600 630 640 650 660 670 pF1KB9 VGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY XP_016 QNPHSSELPTLNFQDTVNTLTNSPAIPLETSACQDIPTSANVQNAEGTKWGEEALKMDLD 610 620 630 640 650 660 >>XP_005247318 (OMIM: 612218) PREDICTED: zinc finger and (1195 aa) initn: 756 init1: 442 opt: 442 Z-score: 193.4 bits: 47.0 E(85289): 0.0005 Smith-Waterman score: 786; 30.3% identity (58.9% similar) in 633 aa overlap (14-613:15-592) 10 20 30 40 50 pF1KB9 MESRKLISATDIQYSGSLLNSLNEQRGHGLFCDVTVIVEDRKFRAHKNILSASSTYFHQ .: ..:. ::::: .:..::::.:::: ::.::.:.:.::: ::.. XP_005 MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKN 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB9 LF-----SVAGQVVELSFIRAEIFAEILNYIYSSKIVRVRSDLLDELIKSGQLLGVKFIA .: ....:.::. ..::.:.::::::::: .: :.. . .: .:. ::..:. XP_005 IFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFLE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB9 ELGVPLSQVKSISGTAQDGNTEPLPPD-SGDKNLVIQKSKDEAQDNGATIM--PIITESF .: : .. .. : : .. :... :.: . . .: : ::..: XP_005 DL------------TDRNFSNSPGPYVFCITEKGVVKEEKNEKRHEEPAITNGPRITNAF 130 140 150 160 180 190 200 210 220 pF1KB9 SLSAEDYEMKKIIVTDSDDDDDDVIFCSEILPT--KETLPSNNTVAQVQSNPGPVAISDV : :: :..... .: : . :.. : :.. .. XP_005 S----------IIETENSNN----MFSPLDLRASFKKVSDSMRTASLCLERTDVCHEAEP 170 180 190 200 210 230 240 250 260 270 280 pF1KB9 APSASNNSPPLTNITPTQK-LPTPVNQATLSQTQGSEKLLVSSAPTHLTPNIILLNQTPL . . ...: ..... . . :. .... . :.:. . .: :. .: . XP_005 VRTLAEHSYAVSSVAEAYRSQPVREHDGSSPGNTGKENCEALAAK----PKTCRKPKT-F 220 230 240 250 260 290 300 310 320 330 340 pF1KB9 STPPNVSSSLPNHMPSSI-NLLVQNQQTPN-SAILTGNKA-NEEEEEEIIDDDDDTISSS : : . .:. : : . :: :.....:. .:.:: .:. :.: . .. .:.. :. XP_005 SIPQDSDSATENIPPPPVSNLEVNQERSPQPAAVLTRSKSPNNEGDVHFSREDENQSSDV 270 280 290 300 310 320 350 360 370 380 390 400 pF1KB9 PDSAVSNTSLVPQADTSQNTSFDGS--LIQKMQIPTLLQEPLSNSLKISDIITRNTNDPG : .... . . . .::.: : .::. :::: . ... : : : XP_005 PGPPAAEVPPLVYNCSCCSKAFDSSTLLSAHMQLHKPTQEPLVCKYCNKQFTTLNRLD-- 330 340 350 360 370 380 410 420 430 440 450 460 pF1KB9 VGSKHLMEGQKIITLDTATEIEGLSTGC-KVYANIGEDTYDIVIPVKDDPDEGEARLENE .: ..: .. : : . . : .::.. ... : .: .: :. .: XP_005 ---RH----EQICMRSSHMPIPGGNQRFLENYPTIGQNGGSFTGP---EPLLSENRI-GE 390 400 410 420 430 470 480 490 500 510 520 pF1KB9 IPKTSGSEMANKRMKVKHDDHYELIVDGRVYYICIVCKRSYVCLTSLRRHFNIHSWEKKY . ...:: . . ::. .:.:.. : :.::::::: :.::::: :.:::.. : XP_005 F-SSTGSTLPDT-------DHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTY 440 450 460 470 480 530 540 550 560 570 pF1KB9 PCRYCEKVFPLAEYRTKHEIHHTGERRYQCLACGKSFINYQFMSSHIKSVHSQD------ ::.::.::: ::::::.::: :::::::::. : ..:..: ....: :: :. : XP_005 PCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSIS 490 500 510 520 530 540 580 590 600 610 620 pF1KB9 ---------PS-GDSKLYRLHPCRSLQIRQYAYLSDRSSTIPAMKDDGIGYKVDTGKEPP :: ::::: : .. .. : : :.:. ... XP_005 KKTANGGLKPSVYPYKLYRLLP---MKCKRAPYKSYRNSSYENARENSQMNESAPGTYVV 550 560 570 580 590 600 630 640 650 660 670 pF1KB9 VGTTTSTQNKPMTWEDIFIQQENDSIFKQNVTDGSTEFEFIIPESY XP_005 QNPHSSELPTLNFQDTVNTLTNSPAIPLETSACQDIPTSANVQNAEGTKWGEEALKMDLD 610 620 630 640 650 660 672 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:03:37 2016 done: Fri Nov 4 17:03:39 2016 Total Scan time: 10.750 Total Display time: 0.090 Function used was FASTA [36.3.4 Apr, 2011]