FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9446, 323 aa 1>>>pF1KB9446 323 - 323 aa - 323 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8678+/-0.000843; mu= 14.9461+/- 0.051 mean_var=104.2718+/-20.797, 0's: 0 Z-trim(109.7): 27 B-trim: 0 in 0/51 Lambda= 0.125600 statistics sampled from 11057 (11076) to 11057 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.34), width: 16 Scan time: 2.660 The best scores are: opt bits E(32554) CCDS32304.1 MORF4L1 gene_id:10933|Hs108|chr15 ( 323) 2170 403.4 1.2e-112 CCDS10307.1 MORF4L1 gene_id:10933|Hs108|chr15 ( 362) 1805 337.3 1.1e-92 CCDS58393.1 MORF4L1 gene_id:10933|Hs108|chr15 ( 235) 1548 290.6 8.3e-79 CCDS14512.1 MORF4L2 gene_id:9643|Hs108|chrX ( 288) 1284 242.8 2.4e-64 >>CCDS32304.1 MORF4L1 gene_id:10933|Hs108|chr15 (323 aa) initn: 2170 init1: 2170 opt: 2170 Z-score: 2135.7 bits: 403.4 E(32554): 1.2e-112 Smith-Waterman score: 2170; 100.0% identity (100.0% similar) in 323 aa overlap (1-323:1-323) 10 20 30 40 50 60 pF1KB9 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 RVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 RVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 GDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 GDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQ 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 LFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 LFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 QYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS32 QYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAK 250 260 270 280 290 300 310 320 pF1KB9 NSATLFSASDYEVAPPEYHRKAV ::::::::::::::::::::::: CCDS32 NSATLFSASDYEVAPPEYHRKAV 310 320 >>CCDS10307.1 MORF4L1 gene_id:10933|Hs108|chr15 (362 aa) initn: 2150 init1: 1796 opt: 1805 Z-score: 1777.6 bits: 337.3 E(32554): 1.1e-92 Smith-Waterman score: 2023; 88.7% identity (89.0% similar) in 355 aa overlap (8-323:8-362) 10 20 30 40 50 pF1KB9 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNK--------- :::::::::::::::::::::::::::::::::::::::::::: CCDS10 MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRS 10 20 30 40 50 60 60 70 80 pF1KB9 ------------------------------NWDEWVPESRVLKYVDTNLQKQRELQKANQ .::::::::::::::::::::::::::::: CCDS10 EKSLKTHEDIVALFPVPEGAPSVHHPLLTSSWDEWVPESRVLKYVDTNLQKQRELQKANQ 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB9 EQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 EQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVD 130 140 150 160 170 180 150 160 170 180 190 200 pF1KB9 PTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 PTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYK 190 200 210 220 230 240 210 220 230 240 250 260 pF1KB9 KSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAP 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB9 HLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 HLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRK 310 320 330 340 350 360 pF1KB9 AV :: CCDS10 AV >>CCDS58393.1 MORF4L1 gene_id:10933|Hs108|chr15 (235 aa) initn: 1548 init1: 1548 opt: 1548 Z-score: 1528.4 bits: 290.6 E(32554): 8.3e-79 Smith-Waterman score: 1548; 100.0% identity (100.0% similar) in 235 aa overlap (89-323:1-235) 60 70 80 90 100 110 pF1KB9 ESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTP :::::::::::::::::::::::::::::: CCDS58 MRGAAPGKKTSGLQQKNVEVKTKKNKQKTP 10 20 30 120 130 140 150 160 170 pF1KB9 GNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 GNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQ 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB9 KQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 KQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFE 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB9 RPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS58 RPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYL 160 170 180 190 200 210 300 310 320 pF1KB9 AKNSATLFSASDYEVAPPEYHRKAV ::::::::::::::::::::::::: CCDS58 AKNSATLFSASDYEVAPPEYHRKAV 220 230 >>CCDS14512.1 MORF4L2 gene_id:9643|Hs108|chrX (288 aa) initn: 1387 init1: 1274 opt: 1284 Z-score: 1268.7 bits: 242.8 E(32554): 2.4e-64 Smith-Waterman score: 1328; 76.1% identity (87.9% similar) in 272 aa overlap (72-323:17-288) 50 60 70 80 90 100 pF1KB9 YFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGL ......: .. .. ..:::::. ::::.: CCDS14 MSSRKQGSQPRGQQSAEEENFKKPTRSNMQRSKMRGASSGKKTAGP 10 20 30 40 110 120 130 140 pF1KB9 QQKNVEV--------------------KTKKNKQKTPGNGDGGSTSETPQPPRKKRARVD ::::.: ::.:::::::::::::::::.::::::::::.: CCDS14 QQKNLEPALPGRWGGRSAENPPSGSVRKTRKNKQKTPGNGDGGSTSEAPQPPRKKRARAD 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB9 PTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYK ::::.::.: ::.:::::::::::::::.::::.::::::: ::::::::.:::.::: : CCDS14 PTVESEEAFKNRMEVKVKIPEELKPWLVEDWDLVTRQKQLFQLPAKKNVDAILEEYANCK 110 120 130 140 150 160 210 220 230 240 250 260 pF1KB9 KSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAP ::.::.::::::::::::::::::::::::::::::::::::::: ::::::::::::: CCDS14 KSQGNVDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILLAHPDAPMSQVYGAP 170 180 190 200 210 220 270 280 290 300 310 320 pF1KB9 HLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRK :::::::::::::::::::::::::::.::::::::::::::.::.::::.:: ::::: CCDS14 HLLRLFVRIGAMLAYTPLDEKSLALLLGYLHDFLKYLAKNSASLFTASDYKVASAEYHRK 230 240 250 260 270 280 pF1KB9 AV :. CCDS14 AL 323 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:25:37 2016 done: Thu Nov 3 23:25:38 2016 Total Scan time: 2.660 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]