FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9448, 487 aa 1>>>pF1KB9448 487 - 487 aa - 487 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.5677+/-0.00095; mu= 12.3649+/- 0.057 mean_var=92.3129+/-18.137, 0's: 0 Z-trim(107.6): 29 B-trim: 440 in 1/51 Lambda= 0.133488 statistics sampled from 9639 (9652) to 9639 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.296), width: 16 Scan time: 3.440 The best scores are: opt bits E(32554) CCDS2307.1 NAB1 gene_id:4664|Hs108|chr2 ( 487) 3199 626.3 2.2e-179 CCDS82545.1 NAB1 gene_id:4664|Hs108|chr2 ( 486) 3180 622.6 2.8e-178 CCDS81701.1 NAB2 gene_id:4665|Hs108|chr12 ( 461) 617 129.0 1e-29 CCDS8930.1 NAB2 gene_id:4665|Hs108|chr12 ( 525) 617 129.1 1.2e-29 >>CCDS2307.1 NAB1 gene_id:4664|Hs108|chr2 (487 aa) initn: 3199 init1: 3199 opt: 3199 Z-score: 3333.8 bits: 626.3 E(32554): 2.2e-179 Smith-Waterman score: 3199; 100.0% identity (100.0% similar) in 487 aa overlap (1-487:1-487) 10 20 30 40 50 60 pF1KB9 MAAALPRTLGELQLYRILQKANLLSYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 MAAALPRTLGELQLYRILQKANLLSYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPTWLGISCSSYERSSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 KPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPTWLGISCSSYERSSNA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REPHLKIPKCAATTCVQSLGQGKSDVVGSLALQSVGESRLWQGHHATESEHSLSPADLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 REPHLKIPKCAATTCVQSLGQGKSDVVGSLALQSVGESRLWQGHHATESEHSLSPADLGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PASPKESSEALDAAAALSVAECVERMAPTLPKSDLNEVKELLKTNKKLAKMIGHIFEMND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PASPKESSEALDAAAALSVAECVERMAPTLPKSDLNEVKELLKTNKKLAKMIGHIFEMND 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 DDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ARQISREVTYKYTYRTTKSKCGERDELSPKRIKVEDGFPDFQDSVQTLFQQARAKSEELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 ARQISREVTYKYTYRTTKSKCGERDELSPKRIKVEDGFPDFQDSVQTLFQQARAKSEELA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ALSSQQPEKVMAKQMEFLCNQAGYERLQHAERRLSAGLYRQSSEEHSPNGLTSDNSDGQG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 ALSSQQPEKVMAKQMEFLCNQAGYERLQHAERRLSAGLYRQSSEEHSPNGLTSDNSDGQG 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 ERPLNLRMPNLQNRQPHHFVVDGELSRLYPSEAKSHSSESLGILKDYPHSAFTLEKKVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 ERPLNLRMPNLQNRQPHHFVVDGELSRLYPSEAKSHSSESLGILKDYPHSAFTLEKKVIK 430 440 450 460 470 480 pF1KB9 TEPEDSR ::::::: CCDS23 TEPEDSR >>CCDS82545.1 NAB1 gene_id:4664|Hs108|chr2 (486 aa) initn: 2382 init1: 2382 opt: 3180 Z-score: 3314.1 bits: 622.6 E(32554): 2.8e-178 Smith-Waterman score: 3180; 99.8% identity (99.8% similar) in 487 aa overlap (1-487:1-486) 10 20 30 40 50 60 pF1KB9 MAAALPRTLGELQLYRILQKANLLSYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MAAALPRTLGELQLYRILQKANLLSYFDAFIQQGGDDVQQLCEAGEEEFLEIMALVGMAS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 KPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPTWLGISCSSYERSSNA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 KPLHVRRLQKALRDWVTNPGLFNQPLTSLPVSSIPIYKLPEGSPTWLGISCSSYERSSNA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 REPHLKIPKCAATTCVQSLGQGKSDVVGSLALQSVGESRLWQGHHATESEHSLSPADLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 REPHLKIPKCAATTCVQSLGQGKSDVVGSLALQSVGESRLWQGHHATESEHSLSPADLGS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 PASPKESSEALDAAAALSVAECVERMAPTLPKSDLNEVKELLKTNKKLAKMIGHIFEMND :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 PASPKESSEALDAAAALSVAECVERMAPTLPKSDLNEVKELLKTNKKLAKMIGHIFEMND 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 DDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 DDPHKEEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFAL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 ARQISREVTYKYTYRTTKSKCGERDELSPKRIKVEDGFPDFQDSVQTLFQQARAKSEELA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ARQISREVTYKYTYRTTKSKCGERDELSPKRIKVEDGFPDFQDSVQTLFQQARAKSEELA 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 ALSSQQPEKVMAKQMEFLCNQAGYERLQHAERRLSAGLYRQSSEEHSPNGLTSDNSDGQG ::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ALSSQ-PEKVMAKQMEFLCNQAGYERLQHAERRLSAGLYRQSSEEHSPNGLTSDNSDGQG 370 380 390 400 410 430 440 450 460 470 480 pF1KB9 ERPLNLRMPNLQNRQPHHFVVDGELSRLYPSEAKSHSSESLGILKDYPHSAFTLEKKVIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 ERPLNLRMPNLQNRQPHHFVVDGELSRLYPSEAKSHSSESLGILKDYPHSAFTLEKKVIK 420 430 440 450 460 470 pF1KB9 TEPEDSR ::::::: CCDS82 TEPEDSR 480 >>CCDS81701.1 NAB2 gene_id:4665|Hs108|chr12 (461 aa) initn: 1089 init1: 576 opt: 617 Z-score: 646.9 bits: 129.0 E(32554): 1e-29 Smith-Waterman score: 1072; 51.1% identity (71.1% similar) in 370 aa overlap (2-342:33-391) 10 20 30 pF1KB9 MAAALPRTLGELQLYRILQKANLLSYFDAFI : :::::::::::::.::.::::::...:: CCDS81 RAPSPTAEQPPGGGDSARRTLQPRLKPSARAMALPRTLGELQLYRVLQRANLLSYYETFI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 QQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALRDWVTNPGLFNQPLTSLPV ::::::::::::::::::::::::::::.:::::::::::::.:.::::::.::. ..:: CCDS81 QQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALREWATNPGLFSQPVPAVPV 70 80 90 100 110 120 100 110 120 130 140 pF1KB9 SSIPIYKLPEGSPTWLGISCSSY----ERSSNAREPHLKIPKCAATTCVQSLGQGKSDVV ::::..:. : . : : ... :....:: : : ::. : . CCDS81 SSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSPKSP--------LELGEKLSPLP 130 140 150 160 170 150 160 170 180 190 pF1KB9 GSLALQSVGESRLWQGHHATESE-HSLSPADLGSPA-SPK------ESSEALDAAAALS- :. ..:. :.: :. . ::. . . . ::: :: :.. : ::. . CCDS81 GG---PGAGDPRIWPGRSTPESDVGAGGEEEAGSPPFSPPAGGGVPEGTGAGGLAAGGTG 180 190 200 210 220 230 200 210 220 230 240 pF1KB9 -------------VAECVERMAPTLPKSDLNEVKELLKTNKKLAKMIGHIFEMNDDDPHK :.: :::. ..:..: .:: ::: :::::. .::::::.:.: .: CCDS81 GGPDRLEPEMVRMVVESVERIFRSFPRGDAGEVTSLLKLNKKLARSVGHIFEMDDNDSQK 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB9 EEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFALARQIS :::::::: :::::::::..::.:.:::::.::::::.:..::.:: :: :::.:.::.. CCDS81 EEEIRKYSIIYGRFDSKRREGKQLSLHELTINEAAAQFCMRDNTLLLRRVELFSLSRQVA 300 310 320 330 340 350 310 320 330 340 350 360 pF1KB9 REVTYKYTYRTTKSKCGERDELSPKRIKVEDG---FPDFQDSVQTLFQQARAKSEELAAL :: :: . . .. . : :..: : : :..: CCDS81 RESTYLSSLKGSRLHPEELGGPPLKKLKQEVGEQSHPEIQQPPPGPESYVPPYRPSLEED 360 370 380 390 400 410 370 380 390 400 410 420 pF1KB9 SSQQPEKVMAKQMEFLCNQAGYERLQHAERRLSAGLYRQSSEEHSPNGLTSDNSDGQGER CCDS81 SASLSGESLDGHLQEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ 420 430 440 450 460 >>CCDS8930.1 NAB2 gene_id:4665|Hs108|chr12 (525 aa) initn: 1095 init1: 576 opt: 617 Z-score: 646.0 bits: 129.1 E(32554): 1.2e-29 Smith-Waterman score: 1072; 51.1% identity (71.1% similar) in 370 aa overlap (2-342:33-391) 10 20 30 pF1KB9 MAAALPRTLGELQLYRILQKANLLSYFDAFI : :::::::::::::.::.::::::...:: CCDS89 RAPSPTAEQPPGGGDSARRTLQPRLKPSARAMALPRTLGELQLYRVLQRANLLSYYETFI 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB9 QQGGDDVQQLCEAGEEEFLEIMALVGMASKPLHVRRLQKALRDWVTNPGLFNQPLTSLPV ::::::::::::::::::::::::::::.:::::::::::::.:.::::::.::. ..:: CCDS89 QQGGDDVQQLCEAGEEEFLEIMALVGMATKPLHVRRLQKALREWATNPGLFSQPVPAVPV 70 80 90 100 110 120 100 110 120 130 140 pF1KB9 SSIPIYKLPEGSPTWLGISCSSY----ERSSNAREPHLKIPKCAATTCVQSLGQGKSDVV ::::..:. : . : : ... :....:: : : ::. : . CCDS89 SSIPLFKISETAGTRKGSMSNGHGSPGEKAGSARSFSPKSP--------LELGEKLSPLP 130 140 150 160 170 150 160 170 180 190 pF1KB9 GSLALQSVGESRLWQGHHATESE-HSLSPADLGSPA-SPK------ESSEALDAAAALS- :. ..:. :.: :. . ::. . . . ::: :: :.. : ::. . CCDS89 GG---PGAGDPRIWPGRSTPESDVGAGGEEEAGSPPFSPPAGGGVPEGTGAGGLAAGGTG 180 190 200 210 220 230 200 210 220 230 240 pF1KB9 -------------VAECVERMAPTLPKSDLNEVKELLKTNKKLAKMIGHIFEMNDDDPHK :.: :::. ..:..: .:: ::: :::::. .::::::.:.: .: CCDS89 GGPDRLEPEMVRMVVESVERIFRSFPRGDAGEVTSLLKLNKKLARSVGHIFEMDDNDSQK 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB9 EEEIRKYSAIYGRFDSKRKDGKHLTLHELTVNEAAAQLCVKDNALLTRRDELFALARQIS :::::::: :::::::::..::.:.:::::.::::::.:..::.:: :: :::.:.::.. CCDS89 EEEIRKYSIIYGRFDSKRREGKQLSLHELTINEAAAQFCMRDNTLLLRRVELFSLSRQVA 300 310 320 330 340 350 310 320 330 340 350 360 pF1KB9 REVTYKYTYRTTKSKCGERDELSPKRIKVEDG---FPDFQDSVQTLFQQARAKSEELAAL :: :: . . .. . : :..: : : :..: CCDS89 RESTYLSSLKGSRLHPEELGGPPLKKLKQEVGEQSHPEIQQPPPGPESYVPPYRPSLEED 360 370 380 390 400 410 370 380 390 400 410 420 pF1KB9 SSQQPEKVMAKQMEFLCNQAGYERLQHAERRLSAGLYRQSSEEHSPNGLTSDNSDGQGER CCDS89 SASLSGESLDGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLVS 420 430 440 450 460 470 487 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:26:17 2016 done: Thu Nov 3 23:26:17 2016 Total Scan time: 3.440 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]