FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9451, 332 aa 1>>>pF1KB9451 332 - 332 aa - 332 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 12.0626+/-0.000403; mu= -12.9465+/- 0.025 mean_var=446.5607+/-90.409, 0's: 0 Z-trim(124.6): 22 B-trim: 62 in 1/61 Lambda= 0.060692 statistics sampled from 46408 (46464) to 46408 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.795), E-opt: 0.2 (0.545), width: 16 Scan time: 10.430 The best scores are: opt bits E(85289) NP_002347 (OMIM: 177061) myristoylated alanine-ric ( 332) 2119 199.0 1.2e-50 NP_075385 (OMIM: 602940) MARCKS-related protein [H ( 195) 310 40.4 0.0038 >>NP_002347 (OMIM: 177061) myristoylated alanine-rich C- (332 aa) initn: 2119 init1: 2119 opt: 2119 Z-score: 1030.5 bits: 199.0 E(85289): 1.2e-50 Smith-Waterman score: 2119; 100.0% identity (100.0% similar) in 332 aa overlap (1-332:1-332) 10 20 30 40 50 60 pF1KB9 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 EAAVAPEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAAPAEE 250 260 270 280 290 300 310 320 330 pF1KB9 PAAAAASSACAAPSQEAQPECSPEAPPAEAAE :::::::::::::::::::::::::::::::: NP_002 PAAAAASSACAAPSQEAQPECSPEAPPAEAAE 310 320 330 >>NP_075385 (OMIM: 602940) MARCKS-related protein [Homo (195 aa) initn: 359 init1: 163 opt: 310 Z-score: 177.5 bits: 40.4 E(85289): 0.0038 Smith-Waterman score: 352; 37.8% identity (55.4% similar) in 267 aa overlap (1-263:1-195) 10 20 30 40 50 60 pF1KB9 MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQA ::.: :: : .:...:: ::: ..::.::::::::::: ::: :: .. NP_075 MGSQSSK-APRGDVTAE---EAA-GASPAKANGQENGHVKSNGDLSP-----------KG 10 20 30 40 70 80 90 100 110 120 pF1KB9 NGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGASPVEKEAPAEGEAAEPGSPT .: .: .. . ::...: : ::: : :..: :: NP_075 EGESPPVNGTDEAAGATGDAI-------EPA----P-----------PSQG--AE----- 50 60 70 130 140 150 160 170 180 pF1KB9 AAEGEAASAASSTSSPKAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGE :.::. : .:::::::: ::::: :::::.:::.:.::.: NP_075 -AKGEV-------------------PPKETPKKKKK-FSFKKPFKLSGLSFKRNRKEGGG 80 90 100 110 190 200 210 220 230 pF1KB9 GGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAP--GEEAAAGEEGAAGGDPQEAK . : .:. : .. : .: . :. : :. ::.: : : : :..:... .:: NP_075 DSSASSPTEE---EQEQGEIGACSDEGTAQEGKAAATPESQEPQAKGAEASAASE-EEAG 120 130 140 150 160 170 240 250 260 270 280 290 pF1KB9 PQEAAVAPEKP--PASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPGAPPEQEAA :: :. : : : : : :. : .. NP_075 PQ--ATEPSTPSGPESGPTPASAEQNE 180 190 332 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:04:13 2016 done: Fri Nov 4 17:04:14 2016 Total Scan time: 10.430 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]