FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB9457, 832 aa 1>>>pF1KB9457 832 - 832 aa - 832 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.1749+/-0.00117; mu= 10.8298+/- 0.070 mean_var=345.9862+/-75.281, 0's: 0 Z-trim(113.0): 72 B-trim: 716 in 1/53 Lambda= 0.068952 statistics sampled from 13615 (13681) to 13615 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.42), width: 16 Scan time: 4.530 The best scores are: opt bits E(32554) CCDS6540.1 NFX1 gene_id:4799|Hs108|chr9 ( 833) 6205 632.2 1.1e-180 CCDS6538.1 NFX1 gene_id:4799|Hs108|chr9 (1120) 6043 616.3 9.3e-176 CCDS3478.2 NFXL1 gene_id:152518|Hs108|chr4 ( 911) 861 100.6 1.2e-20 >>CCDS6540.1 NFX1 gene_id:4799|Hs108|chr9 (833 aa) initn: 6435 init1: 6060 opt: 6205 Z-score: 3357.3 bits: 632.2 E(32554): 1.1e-180 Smith-Waterman score: 6205; 99.9% identity (99.9% similar) in 833 aa overlap (1-832:1-833) 10 20 30 40 50 60 pF1KB9 MAEAPPVSGTFKFNTDAAEFIPQEKKNSGLNCGTQRRLDSNRIGRRNYSSPPPCHLSRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MAEAPPVSGTFKFNTDAAEFIPQEKKNSGLNCGTQRRLDSNRIGRRNYSSPPPCHLSRQV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PYDEISAVHQHSYHPSGSKPKSQQTSFQSSPCNKSPKSHGLQNQPWQKLRNEKHHIRVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 PYDEISAVHQHSYHPSGSKPKSQQTSFQSSPCNKSPKSHGLQNQPWQKLRNEKHHIRVKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQSLAEQTSDTAGLESSTRSESGTDLREHSPSESEKEVVGADPRGAKPKKATQFVYSYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 AQSLAEQTSDTAGLESSTRSESGTDLREHSPSESEKEVVGADPRGAKPKKATQFVYSYGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GPKVKGKLKCEWSNRTTPKPEDAGPESTKPVGVFHPDSSEASSRKGVLDGYGARRNEQRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 GPKVKGKLKCEWSNRTTPKPEDAGPESTKPVGVFHPDSSEASSRKGVLDGYGARRNEQRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YPQKRPPWEVEGARPRPGRNPPKQEGHRHTNAGHRNNMGPIPKDDLNERPAKSTCDSENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 YPQKRPPWEVEGARPRPGRNPPKQEGHRHTNAGHRNNMGPIPKDDLNERPAKSTCDSENL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AVINKSSRRVDQEKCTVRRQDPQVVSPFSRGKQNHVLKNVETHTGSLIEQLTTEKYECMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 AVINKSSRRVDQEKCTVRRQDPQVVSPFSRGKQNHVLKNVETHTGSLIEQLTTEKYECMV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CCELVRVTAPVWSCQSCYHVFHLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPNTYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CCELVRVTAPVWSCQSCYHVFHLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPNTYT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 CFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCPPCPAFMTKTCECG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCPPCPAFMTKTCECG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 RTRHTVRCGQAVSVHCSNPCENILNCGQHQCAELCHGGQCQPCQIILNQVCYCGSTSRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 RTRHTVRCGQAVSVHCSNPCENILNCGQHQCAELCHGGQCQPCQIILNQVCYCGSTSRDV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LCGTDVGKSDGFGDFSCLKICGKDLKCGNHTCSQVCHPQPCQQCPRLPQLVRCCPCGQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LCGTDVGKSDGFGDFSCLKICGKDLKCGNHTCSQVCHPQPCQQCPRLPQLVRCCPCGQTP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LSQLLELGSSSRKTCMDPVPSCGKVCGKPLPCGSLDFIHTCEKLCHEGDCGPCSRTSVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LSQLLELGSSSRKTCMDPVPSCGKVCGKPLPCGSLDFIHTCEKLCHEGDCGPCSRTSVIS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 CRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHKCPLICGRKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHKCPLICGRKLR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 CGLHRCEEPCHRGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARVHECDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CGLHRCEEPCHRGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARVHECDH 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 PVYHSCHSEEKCPPCTFLTQKWCMGKHE-SHYWASTQKKRSHYMKKIPAHACL :::::::::::::::::::::::::::: :::::::::::::::::::::::: CCDS65 PVYHSCHSEEKCPPCTFLTQKWCMGKHEQSHYWASTQKKRSHYMKKIPAHACL 790 800 810 820 830 >>CCDS6538.1 NFX1 gene_id:4799|Hs108|chr9 (1120 aa) initn: 6043 init1: 6043 opt: 6043 Z-score: 3268.9 bits: 616.3 E(32554): 9.3e-176 Smith-Waterman score: 6043; 100.0% identity (100.0% similar) in 808 aa overlap (1-808:1-808) 10 20 30 40 50 60 pF1KB9 MAEAPPVSGTFKFNTDAAEFIPQEKKNSGLNCGTQRRLDSNRIGRRNYSSPPPCHLSRQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MAEAPPVSGTFKFNTDAAEFIPQEKKNSGLNCGTQRRLDSNRIGRRNYSSPPPCHLSRQV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB9 PYDEISAVHQHSYHPSGSKPKSQQTSFQSSPCNKSPKSHGLQNQPWQKLRNEKHHIRVKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 PYDEISAVHQHSYHPSGSKPKSQQTSFQSSPCNKSPKSHGLQNQPWQKLRNEKHHIRVKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB9 AQSLAEQTSDTAGLESSTRSESGTDLREHSPSESEKEVVGADPRGAKPKKATQFVYSYGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 AQSLAEQTSDTAGLESSTRSESGTDLREHSPSESEKEVVGADPRGAKPKKATQFVYSYGR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB9 GPKVKGKLKCEWSNRTTPKPEDAGPESTKPVGVFHPDSSEASSRKGVLDGYGARRNEQRR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 GPKVKGKLKCEWSNRTTPKPEDAGPESTKPVGVFHPDSSEASSRKGVLDGYGARRNEQRR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB9 YPQKRPPWEVEGARPRPGRNPPKQEGHRHTNAGHRNNMGPIPKDDLNERPAKSTCDSENL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 YPQKRPPWEVEGARPRPGRNPPKQEGHRHTNAGHRNNMGPIPKDDLNERPAKSTCDSENL 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB9 AVINKSSRRVDQEKCTVRRQDPQVVSPFSRGKQNHVLKNVETHTGSLIEQLTTEKYECMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 AVINKSSRRVDQEKCTVRRQDPQVVSPFSRGKQNHVLKNVETHTGSLIEQLTTEKYECMV 310 320 330 340 350 360 370 380 390 400 410 420 pF1KB9 CCELVRVTAPVWSCQSCYHVFHLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPNTYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CCELVRVTAPVWSCQSCYHVFHLNCIKKWARSPASQADGQSGWRCPACQNVSAHVPNTYT 370 380 390 400 410 420 430 440 450 460 470 480 pF1KB9 CFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCPPCPAFMTKTCECG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CFCGKVKNPEWSRNEIPHSCGEVCRKKQPGQDCPHSCNLLCHPGPCPPCPAFMTKTCECG 430 440 450 460 470 480 490 500 510 520 530 540 pF1KB9 RTRHTVRCGQAVSVHCSNPCENILNCGQHQCAELCHGGQCQPCQIILNQVCYCGSTSRDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 RTRHTVRCGQAVSVHCSNPCENILNCGQHQCAELCHGGQCQPCQIILNQVCYCGSTSRDV 490 500 510 520 530 540 550 560 570 580 590 600 pF1KB9 LCGTDVGKSDGFGDFSCLKICGKDLKCGNHTCSQVCHPQPCQQCPRLPQLVRCCPCGQTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LCGTDVGKSDGFGDFSCLKICGKDLKCGNHTCSQVCHPQPCQQCPRLPQLVRCCPCGQTP 550 560 570 580 590 600 610 620 630 640 650 660 pF1KB9 LSQLLELGSSSRKTCMDPVPSCGKVCGKPLPCGSLDFIHTCEKLCHEGDCGPCSRTSVIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LSQLLELGSSSRKTCMDPVPSCGKVCGKPLPCGSLDFIHTCEKLCHEGDCGPCSRTSVIS 610 620 630 640 650 660 670 680 690 700 710 720 pF1KB9 CRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHKCPLICGRKLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CRCSFRTKELPCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHKCPLICGRKLR 670 680 690 700 710 720 730 740 750 760 770 780 pF1KB9 CGLHRCEEPCHRGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARVHECDH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 CGLHRCEEPCHRGNCQTCWQASFDELTCHCGASVIYPPVPCGTRPPECTQTCARVHECDH 730 740 750 760 770 780 790 800 810 820 830 pF1KB9 PVYHSCHSEEKCPPCTFLTQKWCMGKHESHYWASTQKKRSHYMKKIPAHACL :::::::::::::::::::::::::::: CCDS65 PVYHSCHSEEKCPPCTFLTQKWCMGKHEFRSNIPCHLVDISCGLPCSATLPCGMHKCQRL 790 800 810 820 830 840 >>CCDS3478.2 NFXL1 gene_id:152518|Hs108|chr4 (911 aa) initn: 608 init1: 366 opt: 861 Z-score: 483.9 bits: 100.6 E(32554): 1.2e-20 Smith-Waterman score: 1349; 34.8% identity (55.5% similar) in 587 aa overlap (252-801:43-584) 230 240 250 260 270 280 pF1KB9 SSRKGVLDGYGARRNEQRRYPQKRPPWEVEGARPRPGRNPPKQEGHRHTNAGHRNNMGPI :: : : .: : :.:. . .: CCDS34 GRSRGRATAAPSGNGVHLRGAGGGREKGSVGAVPS-GTSP----GGVATTAAAGSRHSPA 20 30 40 50 60 290 300 310 320 330 pF1KB9 PKDDLNERPAKSTCDSENLAVINKSS----RRVDQEKCTVRRQDPQVVSPFSRGKQNHVL .. :. :. ..... :.:.. :.. .:. . .. . : .:::...: CCDS34 GSQALQTTAASELMSQKKFEEIKKANQAAARKLVEEQFSSSSEEGD--EDF-EGKQGKIL 70 80 90 100 110 120 340 350 360 370 380 pF1KB9 KNV----ETHT-GSLIEQLTTEKY----------ECMVCCELVRVTAPVWSCQSCYHVFH :. :.: :. : :..: :..: :. . ::::..:. .:: CCDS34 ANTFITYTTQTDGDTRELERTKQYVNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFH 130 140 150 160 170 180 390 400 410 420 430 pF1KB9 LNCIKKWARSP----ASQADGQSG-----WRCPAC--QNVSAHVPNTYTCFCGKVKNPEW . ::.:::.. .: .: . : : :: : . ...:. : :.::::..: CCDS34 MPCIQKWAKDSQFLVSSVTDDDFGKKDCPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPL 190 200 210 220 230 240 440 450 460 470 480 490 pF1KB9 SRNEIPHSCGEVCRKK-QPGQDCPHSCNLLCHPGPCPPCPAFMTKTCECGRTRHTVRCGQ . .:::::.::... .: : :.: :::::::::::: ..: :: : ... : . CCDS34 DPWLVPHSCGQVCEREFKP--PCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCS 250 260 270 280 290 300 500 510 520 530 540 550 pF1KB9 AVSVHCSNPCENILNCGQHQCAELCHGGQCQPCQIILNQVCYCGSTSRDVLCGTDVGKSD : :. :: . : ::::.: . ::.:.:::: . : : ::. . :.. . CCDS34 AKEWSCQLPCGQKLLCGQHKCENPCHAGSCQPCPRVSRQKCVCGKKVAERSCASPL---- 310 320 330 340 350 560 570 580 590 600 610 pF1KB9 GFGDFSCLKICGKDLKCGNHTCSQVCHPQPCQQCPRLPQLVRCCPCGQTPLSQLLELGSS . : ..::: : :::::: :::: : .::: . : ::: .. .: CCDS34 ----WHCDQVCGKTLPCGNHTCEQVCHVGACGECPRSGK--RFCPCQKSKFSL------- 360 370 380 390 400 620 630 640 650 660 670 pF1KB9 SRKTCMDPVPSCGKVCGKPLPCGSLDFIHTCEKLCHEGDCGPCSRTSVISCRCSFRTKEL : . ::.:: : : : :: :: : . ::.: : : . :::. .::.. CCDS34 ---PCTEDVPTCGDSCDKVLECG----IHRCSQRCHRGPCETCRQEVEKHCRCGKHTKRM 410 420 430 440 450 680 690 700 710 720 730 pF1KB9 PCTSLKSEDATFMCDKRCNKKRLCGRHKCNEICCVDKEHKCPLICGRKLRCGLHRCEEPC :: . ..:. .: : : : .:.: . :: . : ::: : : :.: : CCDS34 PCHK------PYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVC 460 470 480 490 500 510 740 750 760 770 780 pF1KB9 HRGNCQTCWQASFDELTCHCGASVIYPPVPCG----TRPPECTQTCARVHECDHPVY--H :::.: : .. .. :.:: . . :::: ::::.: . :.: : : : CCDS34 HRGSCYPCPETV--DVKCNCGNTKV--TVPCGRERTTRPPKCKEQCSRPPTCHHTSQEKH 520 530 540 550 560 790 800 810 820 830 pF1KB9 SCHSEEKCPPCTFLTQKWCMGKHESHYWASTQKKRSHYMKKIPAHACL :: .:::: :: CCDS34 RCHFG-SCPPCHQPCQKVLEKCGHLCPAPCHDQALIKQTGRHQPTGPWEQPSEPAFIQTA 570 580 590 600 610 620 832 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Nov 3 23:29:48 2016 done: Thu Nov 3 23:29:49 2016 Total Scan time: 4.530 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]